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The Design, Enactment, And Impact Of An Inquiry-Based Undergraduate Astronomy Laboratory Learning Environment, Steven A. Stewart

Science Teaching - Dissertations

This study investigated the design, enactment, and impact of an undergraduate, inquiry-based astronomy laboratory learning environment. The professor, Richard, adopted laboratory materials from the Center for Astronomy and Physics Education Research [CAPER] which were described by the group as inquiry-based. Students worked through these laboratory materials under the supervision of teaching assistants [TAs], and Richard led weekly TA meetings to monitor and instruct the TAs on his expectations. This study suggests that Richard was unsure of laboratory materials' learning goals and had received limited guidance on how to use and implement CAPER's materials. TAs also received limited guidance on how …

The Future Of Gene Patents And The Implications For Medicine, Jacob S. Sherkow, Henry Greely

Other Publications

The Supreme Court decision in Myriad Genetics struck down the patenting of human genomic DNA. What will this mean for genetic testing and medicine, more broadly?

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 2013), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 2013 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Message from the President
• PCOM Updates
• Development News
• Institutional Heritage: Founders’ Day 2013
• Thoughts on Ethics, Values and Healing:
• Body, Mind, Spirit: How Can We Improve Mental Health Services?
• The Ethics of Youth Suicide and Risk Assessment in Practice
• Linking Faith, Health and Healing
• Ethics in Healthcare Education
• Making Ethical Decisions in Pharmacy Practice
• Class Notes
• In Memoriam
• My Turn Essay
• The Fund for PCOM

Distribution And Length Frequency Of Invasive Lionfish (Pterois Sp.) In The Northern Gulf Of Mexico, Alexander Q. Fogg, Eric R. Hoffmayer, William B. Driggers Iii, Matthew D. Campbell, Gilmore J. Pellegrin, William Stein

Gulf and Caribbean Research

The purpose of this communication is to document continued spatial expansion of lionfish farther west into the northern Gulf of Mexico. Furthermore, we provide the first length— mass relationships and length frequency information for lionfishes captured within the northern GOM based on data collected as part of a broader on—going study of lionfish life history in this region.

Effects Of Black Mangrove (Avicennia Germinans) Expansion On Saltmarsh (Spartina Alterniflora) Benthic Communities Of The South Texas Coast, Jessica Lunt, Kimberly Mcglaun, Elizabeth M. Robinson

Gulf and Caribbean Research

This study examined the effects of mangrove expansion on benthic communities. This was accomplished by examining plant composition, benthic community composition, and belowground root biomass. Two sites were examined: Corpus Christi Pass, Corpus Christi, TX where mangroves have become more common in the last decade and the Lower Laguna Madre, South Padre Island, TX where mangroves are well established. This research seeks to provide preliminary results to provide direction for future studies examining the interplay of S. alterniflora and A. germinans habitat on benthic communities. We hypothesize that the more established site of South Padre Island will have greater numbers …

Multifunctional Hydroxyapatite And Poly(D,L-Lactide-Co-Glycolide) Nanoparticles For The Local Delivery Of Cholecalciferol, Nenad Ignjatović, Vuk Uskoković, Zorica Ajduković, Dragan Uskoković

Pharmacy Faculty Articles and Research

Cholecalciferol, vitamin D3, plays an important role in bone metabolism by regulating extracellular levels of calcium. Presented here is a study on the effects of the local delivery of cholecalciferol (D3) using nanoparticulate carriers composed of hydroxyapatite (HAp) and poly(D,L-lactide-co-glycolide) (PLGA). Multifunctional nanoparticulate HAp-based powders were prepared for the purpose of: (a) either fast or sustained, local delivery of cholecalciferol, and (b) the secondary, osteoconductive and defect-filling effect of the carrier itself. Two types of HAp-based powders with particles of narrowly dispersed sizes in the nano range were prepared and tested in this study: HAp nanoparticles as direct cholecalciferol delivery …

The Antiinflammatory Action And Pharmacokinetics Of A Novel Glucosamine-Based Di-Peptide Aminosugar, Mohammad H. Gilzad-Kohan, Kamaljit Kaur, Fakhreddin Jamali

Pharmacy Faculty Articles and Research

Purpose. We have previously shown favorable in vitro gut permeability for three novel dipeptide esters of glucosamine (GlcN) likely facilitated by the peptide transporter 1 (PepT1). Herein, we report the development of a novel assay for the determination of bioavailability of the peptide ester of interest, the anti-inflammatory properties of a glycine-valine ester derivative of GlcN (GVG) as well as its pharmacokinetics under healthy and inflammatory conditions.

Methods. A pre-column derivatization (with 9-fluorenylmethoxycarbonyl) HPLC assay was developed to study bioavailability of GVG, GlcN or cleaved GlcN in the rats that were cannulated in their right jugular vein for …

The Bulletin, Undergraduate Catalog 2013-2014 (2013), Minnesota State University Moorhead

Undergraduate Bulletins (Catalogs)

No abstract provided.

Graduate Bulletin, 2013-2014, Minnesota State University Moorhead

Graduate Bulletins (Catalogs)

No abstract provided.

“You Will See My Family Became So American”: Immigration, Racial Visibility, And Specular Citizenship, Sherally Munshi

Studio for Law and Culture

This paper explores the vexed relationship between legal form and personhood that arises in the context of Indian immigration and naturalization in the early twentieth century. In 1932, Dinshah P. Ghadiali received notice that the government was seeking to cancel his citizenship on grounds of “racial ineligibility.” In his self-published writing about the trial, Ghadiali wondered whether he been singled out for persecution by professional rivals. In fact, he had been caught in a larger campaign to denaturalize citizens of Indian origin after the Supreme Court, in United States v. Bhagat Singh Thind (1923), determined that “Hindus” were racially ineligible …

Hackback: Permitting Retaliatory Hacking By Non-State Actors As Proportionate Countermeasures To Transboundary Cyberharm, Jan E. Messerschmidt

National Security Law Program

Cyberespionage has received even greater attention in the wake of reports of persistent and brazen cyberexploitation of U.S. and Canadian firms by the Chinese military. But the recent disclosures about NSA surveillance programs have made clear that a national program of cyberdefense of private firms' intellectual property is politically infeasible. Following the lead

of companies like Google, private corporations may increasingly resort to the use of self-defense, hacking back against cross-border incursions on the Internet. Most scholarship, however, has surprisingly viewed such actions as outside the ambit of international law. This Note provides a novel account of how international law …

Good Lovin': The Effects Of Stressors On Sexual Satisfaction Among Non-Cohabitating, Cohabiting, And Married Couples, Wylie E. Rhoads

EWU Masters Thesis Collection

"The negative relationship between stress and sexual satisfaction is one that has not been studied extensively when it comes to the differences between non-cohabitating, cohabitating, and married couples. It is important to understand how stress may affect sexual satisfaction in different groups so that each group can develop the proper coping mechanisms to defend against the damage stress can cause. The present study examined whether married couples would report more sexual satisfaction before and after a stress- induced priming task due to more effective coping strategies compared to non- cohabitating and cohabitating couples. Men and women in sexually active, monogamous …

Theorizing The Effects Of Color, Environmental Space, Culture And Gender On Communication, David A. Brucker

Browse all Theses and Dissertations

Extant literature indicates it is our physical, psychological interactions, and perceptions with certain colors and space and our culture and gender influence the way we verbally and nonverbally communicate. I discuss how the meanings of different colors have been depicted throughout history. Summarize my research on the physiological and psychological effects on individuals and show how certain colors are used. Describe environmental space in terms of natural, acute, chronic space and the psychological effects of different spaces. Describe how the perception and use of space affects how we feel. Explore how culture strongly influences the "windows" of the world we …

Histone Deacetylation As A Mechanism Of Ypel3 Down-Regulation In Er-A Positive Breast Cancer Cell Lines, Remah Ali

Browse all Theses and Dissertations

YPEL3 is a growth inhibitory gene that was established by our laboratory to trigger senescence in both primary and tumor cells. We recently reported YPEL3 to be directly repressed by estrogen in estrogen receptor-a positive (ER-a +ve) breast cancer cell lines. Here, we set out to determine whether the repression of YPEL3 involves histone deacetylation and, if so, elucidate the molecular mechanism of this activity. MCF-7, T-47D, and ZR-75.1 (all ER-a +ve) breast cancer cell lines were treated with varying doses of the global histone deacetylase inhibitors (HDACIs), trichostatin A (TSA) or suberoyl anilide hydroxamic acid (SAHA), for 24, 48 …

Stochastic Optimization: Theory And Applications, Bin Wang, Lotfollah Najjar, Neal N. Xiong, Rung Ching Chen

Information Systems and Quantitative Analysis Faculty Publications

As an important branch of applied mathematics, optimization theory, especially stochastic optimization, becomes an important tool for solving multiobjective decision-making problems in random process recently. Many kinds of industrial, biological, engineering, and economic problems can be viewed as stochastic systems, for example, area of communication, gene, signal processing, geography, civil engineering, aerospace, banking, and so forth. Stochastic optimization is suitable to solve the decision-making problems in these stochastic systems.

Bringing Families Together: Parent-Student Reunification Procedures In School Crisis Planning, Ashleigh Welko

Master of Public Health Program Student Publications

The purpose of this paper is to evaluate and review current best practices with regard to parent-student reunification procedures following crises in schools. No national recommendations for school crisis planning exist, resulting in varying degrees of completeness in school planning. Parent-student reunification is one of the most frequently ignored or under-developed aspects of school emergency planning, yet a poorly developed reunification plan has the potential to become an enormous source of chaos in the aftermath of school crisis. Expedient reunification reduces the potential for lasting trauma to both children and their parents. A best practices review of existing literature was …

Parasites In Paraguay: An Analysis Of The Presentation And Management Of Intestinal Parasites By Short-Term Medical Mission Volunteers In Paraguay, Robert A. Eick

Master of Public Health Program Student Publications

Introduction. International medical aid in the form of short-term medical missions (STTMs) receives more than $250 million in annual donations. Needs assessments prior to the STTM and outcomes analysis for improvement are often lacking. Objective. Describe the patient population attended to during a one-week STTM in Paraguay, South America, while examining “parasites” as a presenting concern, as a diagnosis by the providers, and the prescription of antiparasitic treatment. This analysis identified variance in intestinal parasite presentation and management by age, gender, and location. The administration frequency of antiparasitic medication was considered as prophylactic versus disease-treatment based.

Methods. This study was …

A Case For Gun Violence Prevention In Medical And Public Health Curriculum, Shaun Hamilton

Master of Public Health Program Student Publications

Gun violence profoundly impacts the landscape of violence in the United States. The costs of gun injuries are, estimated to be $100 billion each year in the United States. Although many physicians and health professionals agree that they have a role to play in the prevention of violence (American Academy of Pediatrics [AAP], 2002), there is a distinct disconnect between perceived responsibility and actual practice (Sidelinger, Guerrero, Rodriguez-Frau, & Mirabal-Colon, 2005). Physicians inherently have a role to play in the prevention of violence. The nature of their occupation places them in the “process” of violence in the form of treatment. …

Caspase-Cleaved Glial Fibrillary Acidic Protein Within Cerebellar White Matter Of The Alzheimer's Disease Brain, Troy T. Rohn, Lindsey W. Catlin, Wayne W. Poon

Biology Faculty Publications and Presentations

Although the cerebellum is generally thought of as an area spared of Alzheimer's disease (AD) pathology, recent evidence suggests that balance and mobility dysfunction may be magnified in affected individuals. In the present study, we sought to determine the degree of pathological changes within the cerebellum utilizing an antibody that specifically detects caspase-cleaved GFAP within degenerating astrocytes. Compared to control subjects, application of this antibody, termed the GFAP caspase-cleavage product (GFAPccp) antibody, revealed widespread labeling in cerebellar white matter with little staining observed in grey matter. Staining was observed within damaged astrocytes, was often localized near blood vessels and co-localized …

Cancer Treatment Using Natriuretic Peptides, David L. Vesely

USF Patents

The present invention includes a method of utilizing four peptide hormones to inhibit the growth of cancer(s). A dramatic decrease in the number of human pancreatic adenocarcinoma cells (i.e., the type of cancer with the highest mortality, with patients only surviving four months) was observed responsive to treatment. The application of the invention would be to utilize one or more of these peptide hormones alone and/or in combination to treat cancer. The ability of these peptide hormones to decrease the number of adenocarcinoma cells has implications for adenocarcinomas at other sites in the body with the majority of cancers of …

Effects Of Endothelial Progenitor Cell-Derived Microvesicles On Hypoxia/Reoxygenation-Induced Endothelial Dysfunction And Apoptosis, Jinju Wang, Shuzhen Chen, Xioatang Ma, Chuanfang Cheng, Xiang Xiao, Ji Chen, Shiming Liu, Bin Zhao, Yanfang Chen

Pharmacology and Toxicology Faculty Publications

Oxidative stress-induced endothelial dysfunction plays a key role in ischemia/reperfusion injury. Recent evidence indicates that endothelial progenitor cell-derived microvesicles (EPC-MVs) can promote angiogenesis of endothelial cells (ECs). Here, we investigated the potential effects of EPC-MVs on hypoxia/reoxygenation (H/R) injury in human brain microvascular ECs (hb-ECs). MVs were prepared from EPCs cultured in a serum deprivation (SD) medium (starving stress, sEPC-MVs) or SD medium containing tumor necrosis factor-α (TNFα) (apoptotic stress, aEPC-MVs). H/R injury model of hb-ECs was produced by 6 hr hypoxia (1% O₂) and 24 hr reoxygenation. The H/R hb-ECs were co-cultured with EPC-MVs. Results showed that …

Annual Report Ay 2012-13, Center For Innovative Pedagogy

Annual Reports and Newsletters

No abstract provided.

Survival In Soviet Gulags: A Secondary Analysis, Kimberly M. Maas, Paul Prew, Elizabeth J. Sandell

Elementary and Literacy Education Department Publications

One of the most common book series on the subject of Soviet Gulags is Evgenia Ginzburg’s “Journey into the Whirlwind” and “Within the Whirlwind.” This paper will use secondary analysis from anthology works with stories similar to Ginzburg's in combination with the works of several other authors like Anne Applebaum (2011) and Geith and Jolluck (2011). It shall also examine extensively Raphaël Lemkin’s definition of genocide and how it fits to what happened in the Gulags. It shall be argued why certain situations that occurred within the Gulags fit this definition. It will also explore the intimate details and lives …

Stop Talking: Indigenous Ways Of Teaching And Learning And Difficult Dialogues In Higher Education, Larry Merculieff, Libby Roderick

Books

It was the end of spring semester here in Anchorage, Alaska. The snow was gone in all but the shadiest of places, but the trees were not yet in leaf, and a brown dust blew lightly over the still winter-flattened earth. It was a season of endings and beginnings. Finals were over, grades turned in, robes donned, commencement hats flung. Summer was on its way. Just before the faculty went off contract and scattered to the mid-May winds, we held the last meeting of our Ford Foundation-sponsored Difficult Dialogues project. We’d been working together for the past two years on …

Herbicide-Resistant Soybeans In Arkansas: Lessons Learned And Future Direction, Amy May West, Raven Bough, Hayley Jernigan, Mike Norton, Katie Beth Thomas, Curt R. Rom, Michael E. Vayda

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

In Arkansas Delta soybean production, glyphosate resistant (GR) Palmer amaranth has significantly impacted weed management. The incidence of herbicide resistant (HR) weeds has far-reaching crop science, economic, and communications implications, which have been explored by the corresponding expertise of our research team members to form a comprehensive literature review. The review was used to develop policy recommendations to address current and future HR genetically modified (GM) crop use and the associated issues. The review of crop science research indicated an overall increase in herbicide application, as well as an increase in weed management programs focused around glyphosate rather than the …

Evaluation Of Cover Crops In High Tunnel Vegetable Rotation, Tyler A. Patrick, Neal Mays, Jason Mcafee, Curt R. Rom

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Organic vegetable production within high tunnels allows for an extended growing season, crop protection, and environmental control. The USDA National Organic Program (NOP) standards mandate evidence that the soil has been maintained and improved over the course of production. Previous studies have indicated the potential of cover crops for reducing competitive vegetation, and improving soil quality, thus resulting in greater plant growth, nutrient uptake, and yield. However, there has been limited work in the confines of high tunnels as part of a tunnel-system rotation. Ten nitrogen-fixing and ten non-legume cover crops were established under a high tunnel and evaluated for …

Tannic Acid Coated Gold Nanorods Demonstrate A Distinctive Form Of Endosomal Uptake And Unique Distribution Within Cells, Emily A. Untener, Kristen K. Comfort, Elizabeth I. Maurer, Christin M. Grabinski, Donald A. Comfort, Saber M. Hussain

Chemical and Materials Engineering Faculty Publications

One of the primary challenges associated with nanoparticle-dependent biological applications is that endosomal entrapment in a physiological environment severely limits the desired targeting and functionality of the nanoconstructs. This study sought to overcome that challenge through a systematic approach of gold nanorod (GNR) functionalization: evaluating the influence of both aspect ratio and surface chemistry on targeted cellular internalization rates and preservation of particle integrity. Owing to their unique spectral properties and enhanced surface area, GNRs possess great potential for the advancement of nanobased delivery and imaging applications. However, their ability for efficient intracellular delivery while maintaining their specific physiochemical parameters …

Can Marijuana Be Harmful When Used Prenatally Or During Adolescence?, Penninah Dean

The Science Journal of the Lander College of Arts and Sciences

Marijuana is a popular recreational drug with a strong following campaigning to legalize it for both medicinal and recreational use. This paper serves to illustrate the harmful effects of marijuana use as it pertains to prenatal, adolescent and adult use. By understanding the methods of absorption and mechanism of interaction in the body, we can see a correlation between the effects of marijuana and its toxicity. Through extensive research of case studies on marijuana use we were able to determine marijuana’s harmful effects physically, developmentally and cognitively. Through these methods of research, it can be concluded that marijuana has detrimental …

Full Issue: Volume 6, Number 2

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

The Carcinogenic Effects Of Aspartame, Devora Sara Gelbfish

The Science Journal of the Lander College of Arts and Sciences

Aspartame, one of the most common artificial sweeteners, is used as a food additive worldwide. Because of early experimentation with rats linking aspartame to higher risk of cancer, there is much concern regarding the safety of aspartame. However, analytical review and numerous subsequent studies have disproven previous experimentation and reaffirmed that aspartame consumption in humans does not increase the risk of cancers. At the current time there is no credible evidence to support the idea that aspartame is carcinogenic. The evidence confirms that at current levels of consumption aspartame is a safe alternative to sucrose.