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Health Service Utilization And Stigma Among Hiv-Positive Men-Who-Have-Sex-With Men (Msm) In Rural Appalachia, Roger L. Blackwell Jr

Electronic Theses and Dissertations

ABSTRACT

Health Service Utilization and Stigma among

HIV-Positive Men-Who-Have-Sex-With-Men (MSM) in Rural Appalachia

by

Roger Lee Blackwell

The world has now entered the third decade of the AIDS epidemic. Men-who-have-sex-with-men continue to be disproportionately affected by HIV/AIDS. The United States still struggles in its response to this ongoing crisis in many areas: disease prevention, treatment, and HIV related stigma, prejudice and discrimination. Much of the information reported on MSM living with HIV has come from urban population centers, but only a few studies have focused on HIV positive MSM living in rural areas. Therefore, the overall aim of this dissertation …

Mechanisms Of The Anti-Pneumococcal Function Of C-Reactive Protein, Toh B. Gang

Electronic Theses and Dissertations

Human C-reactive protein (CRP) increases survival of and decreases bacteremia in mice infected with Streptococcus pneumoniae. Such protection of mice against pneumococcal infection is seen only when CRP is administered into mice 6 hours before to 2 hours after the injection of pneumococci, but not when CRP is given to mice at a later time. Our first aim was to define the mechanism of CRP-mediated initial protection of mice against infection. It was proposed that CRP binds to phosphocholine (PCh) moieties present in the cell wall and activates the complement system on the pneumococcal surface that kills the pathogen. …

Chronic Joint Disease Caused By Persistent Chikungunya Virus Infection Is Controlled By The Adaptive Immune Response, David W. Hawman, Kristina A. Stoermer, Stephanie A. Montgomery, Pankaj Pal, Lauren Oko, Michael S. Diamond, Thomas E. Morrison

Open Access Publications

No abstract provided.

Characteristics Of Mild Dengue Virus Infection In Thai Children, In-Kyu Yoon, Anon Srikiatkhachorn, Laura Hermann, Darunee Buddhari, Thomas W. Scott, Richard G. Jarman, Jared Aldstadt, Ananda Nisalak, Suwich Thammapalo, Piraya Bhoomiboonchoo, Mammen P. Mammen, Sharone Green, Robert V. Gibbons, Timothy P. Endy, Alan L. Rothman

Institute for Immunology and Informatics Faculty Publications

A four-year longitudinal cohort and geographic cluster study in rural Thailand was conducted to characterize the clinical spectrum of dengue virus (DENV) infection. Symptomatic DENV infections in the cohort were detected by active school absence-based surveillance that triggered cluster investigations around ill cohort children. Data from 189 cohort children with symptomatic DENV infection and 126 contact children in the clusters with DENV infection were analyzed. Of infected contacts, only 19% were asymptomatic; 81% were symptomatic, but only 65.9% reported fever. Symptom-based case definitions were unreliable for diagnosis. Symptomatic infections in contacts were milder with lower DENV RNA levels than the …

Impacts Of Climate Change On Water Resources And Corresponding Adaptation Strategies Of The Nam Ngum River Basin, Laos, Dumindu Lasitha Jayasekera

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Nam Ngum River Basin (NNRB) in Laos has received attention of foreign investors due to high hydropower development potential and low per capita electricity consumption. The NNRB is rapidly developing due to its hydropower generation potentials while water demands will increase for agricultural and domestic purposes due to population increase and land-use changes. Water availability conditions will be affected with the increasing water demand and climate change may worsen the water availability conditions. Climate is often defined as the weather averaged over time whereas weather describes atmospheric conditions at a particular place and time in terms of air temperature, …

First Report Of Ndm-1-Producing Acinetobacter Baumannii In East Africa, Gunturu Revathi, Kristopher L. Siu, Po-Liang Lu, Li-Yueh Huang

Pathology, East Africa

Background: The emergence of carbapenem-resistant Acinetobacter baumannii (CRAB) was observed in a Kenyan hospital from 2009 to 2010. Further investigation of the dissemination of CRAB isolates and the molecular characterization of associated resistance determinants were therefore performed.

Methods: Antibiotic susceptibilities were determined by broth microdilution and Etest. Metallo-blactamases were detected by Etest method. Clonal relationships were studied by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). b-Lactam and aminoglycoside resistance determinants and the clonal relatedness to widespread European clones were studied by PCR and sequencing.

Results: Sixteen CRAB isolates from 10 patients possessed six pulsotypes; half of the isolates …

High Hiv Incidence Among Persons Who Inject Drugs In Pakistan: Greater Risk With Needle Sharing And Injecting Frequently Among The Homeless., Rab Nawaz Samo, Arshad Altaf, Ajmal Agha, Omrana Pasha, Shafquat Rozi, Ashraf Memon, Saleem Azam, Meridith Blevins, Sten Vermund, Sharaf Ali Shah

Community Health Sciences

BACKGROUND:

The incidence of HIV among persons who inject drugs (PWIDU) has fallen in many nations, likely due to successes of clean needle/syringe exchange and substance abuse treatment and service programs. However in Pakistan, prevalence rates for PWID have risen dramatically. In several cities, prevalence exceeded 20% by 2009 compared to a 2003 baseline of just 0.5%. However, no cohort study of PWID has ever been conducted.

METHODS:

We enrolled a cohort of 636 HIV seronegative PWID registered with three drop-in centers that focus on risk reduction and basic social services in Karachi. Recruitment began in 2009 (March to June) …

Better A Broader Diagnosis Than A Misdiagnosis: The Study Of A Neoplastic Condition In A Male Individual Who Died In Early 20th Century (Coimbra, Portugal), Carina Marques, Ana Luisa Santos, Eugénia Cunha

Anthropology Faculty Publications

The paleopathological record of neoplastic conditions in the past is considered scarce. The detection of tumours in ancient populations is hindered by the quality and quantity of signs visible on the skeleton, the methodological approach, the preservation of remains, and by difficulties of differential diagnosis. The aims of this paper are to report the extensive and multiple osteolytic lesions observed in an adult male and to discuss the possible etiology of these lesions. The individual, a 71-year-old male who died in 1932, is part of the Coimbra Identified Skeletal Collection. Records indicate that he died of a ‘heart lesion’. The …

Bacterial Causes Tonsillitis In Children, Study The Resistance To Antimicrobials And The Effect Of Clove Extracts On Selected Isolated Bacteria., Esam J. Alkalifawi

Baghdad Science Journal

In this study Isolated Pathogenic bacteria which causes Tonsillitis in Children with ages between 3-17 years. They are admitted to Central Children Hospital (Al-Karch) and Ebn-Albalady Hospital (Al-Rusafa). 200 cases were collected which include 120 Male and 80 Female. The result of the recent study shows that the isolation percentage was 40% from Male and 35% from Female. In this study Fifty six isolated were Identified, 20 were β-hemolytic Streptococcus which was Streptococcus pyogenes, formed (36%) from all isolated.6 Pathogenic bacteria wereβ- hemolytic Streptococcus which was Streptococcus pneumoniae formed (11%). The number of Moraxella catarrhalis bacteria was 12 formed (21%), …

Tumor Necrosis Factor -Α, Interleukin-10, Intercellular And Vascular Adhesion Molecules Are Possible Biomarkers Of Disease Severity In Complicated Plasmodium Vivax Isolates From Pakistan., Afsheen Raza, Najia K. Ghanchi, Ali Bin Sarwar Zubairi, Ahmed Raheem, Sobia Nizami, Mohammad Asim Beg

Department of Medicine

Background: Cytokine-mediated endothelial activation pathway is a known mechanism of pathogenesis employed by Plasmodium falciparum to induce severe disease symptoms in human host. Though considered benign, complicated cases of Plasmodium vivax are being reported worldwide and from Pakistan. It has been hypothesized that P.vivax utilizes similar mechanism of pathogenesis, as that of P.falciparum for manifestations of severe malaria. Therefore, the main objective of this study was to characterize the role of cytokines and endothelial activation markers in complicated Plasmodium vivax isolates from Pakistan.

Methods and Principle Findings: A case control study using plasma samples from well-characterized groups suffering from P.vivax …

Distribution And Abundance Of Anopheles Spp. In The Lower Rio Grande Valley, South Texas, Norma Hermelinda Martinez

Theses and Dissertations - UTB/UTPA

This study investigated the relationship between Anopheles abundance, collection sites and environmental variables in the Lower Rio Grande Valley, South Texas. In addition, species composition in the Lower Rio Grande Valley was determined in 2011. A total of 6772 female mosquitoes were identified to six genera and 27 species. The most prevalent genera collected were Culex (53.9%), Ochlerotatus (25.6%) and Aedes (13.6%). Anopheles mosquitoes were collected using resting boxes during summer 2012 at multiple locations along the Lower Rio Grande Valley. ArcGIS was used to identify land cover characteristics and nearest water sources at mosquito collection sites. Estero Llano Grande …

Electrostatic Spray Application Of Food-Grade Organic Acids And Plant Extracts To Decrease Escherichia Coli O157:H7 And Salmonella Typhimurium On Select Produce, Leighanna Maeree Massey

Graduate Theses and Dissertations

Both consumers and suppliers have been negatively affected by an increase in foodborne pathogens contaminating fruits. Consequently, there is a need for the development of more efficient antimicrobials and application techniques to decrease contamination. Natural preservatives such as organic acids and plant extracts have demonstrated promising results in decontaminating produce. In addition, the effectiveness of such preservatives may be enhanced by the use of an electrostatic sprayer. The objective of this research was to determine the combinations and concentrations of organic acids and plant extract that were able to reduce Salmonella Typhimurium (ST) and Escherichia coli O157:H7 (EC) inoculated fruits …

Effect Of Electrostatic Spraying Of Food-Grade Organic And Inorganic Acids, And Grape Seed Extract On Salmonella Typhimurium And Escherichia Coli O157:H7 On Spinach And Iceberg Lettuce, Vijayalakshmi Ganesh

Graduate Theses and Dissertations

The safety of fresh produce is often challenged by the sporadic incidences of outbreaks owing to Salmonella Typhimurium (S.T.) and Escherichia coli O157:H7 (E.c.). Washing and current disinfection strategies do not completely decontaminate leafy greens such as spinach and iceberg lettuce. Therefore, more effective treatments are essential to ensure the microbial safety of the produce at the selling point. Here, a multiple hurdle approach was applied: (1) Natural antimicrobials - organic acids (malic, lactic and tartaric acids; MA, LA, TA, respectively) and plant extract (grape seed extract, GSE) and (2) Application method - Electrostatic spraying, was …

Does The Existing Human Rights Regime Have Political Authority?, Christopher Heath Wellman

San Diego Law Review

In this Article I consider whether the existing international legal human rights regime enjoys political authority over sovereign states. In particular, I explore whether, just as states can cite their role as the primary institutions that protect human rights in order to justify their claim to authority over their citizens, perhaps the current human rights regime might plausibly cite its secondary role in securing human rights in order to ground its authority over these states.

Us Medical Specialty Global Health Training And The Global Burden Of Disease, Vanessa B. Kerry, Rochelle P. Walensky, Alexander C. Tsai, Regan W. Bergmark, Brian A. Bergmark, Chaturia Rouse, David R. Bangsberg

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Rapid growth in global health activity among US medical specialty education programs has lead to heterogeneity in types of activities and global health training models. The breadth and scope of this activity is not well chronicled.

Methods: Using a standardized search protocol, we examined the characteristics of US medical residency global health programs by number of programs, clinical specialty, nature of activity (elective, research, extended curriculum based field training), and geographic location across seven different clinical medical residency education specialties. We tabulated programmatic activity by clinical discipline, region and country. We calculated the Spearman's rank correlation coefficient to estimate …

Pengaruh Jenis Kelamin Dan Kebiasaan Merokok Terhadap Kadar Timbal Darah, Wirsal Hasan, Abdul Rahim Matondang, Alvi Syahrin, Chatarina Umbul Wahyuni

Kesmas

Penarik becak dayung dan becak bermesin, pengatur lalu lintas, pedagang asongan, dan pedagang kaki lima banyak terpapar dengan polusi timbal dari udara ambien yang merupakan ancaman terhadap para pekerja pinggir jalan. Penelitian ini bertujuan mengetahui hubungan karakteristik responden dengan kadar timbal dalam darah. Sampel dalam penelitian ini berjumlah 109 orang terdiri dari 58 orang penarik becak dayung, 30 orang penarik becak bermesin dan 21 orang pedagang kaki lima yang ditarik secara consecutive sampling. Hasil penelitian menunjukkan bahwa tidak ada korelasi yang signifikan antara variabel usia, tekanan darah sistolik dan tekanan darah diastolik terhadap kadar timbal dalam darah (p>0,05). Rerata …

Pentingnya Analisis Cluster Berbasis Spasial Dalam Penanggulangan Tuberkulosis Di Indonesia, Dyah Wulan Sumekar Rengganis Wardani, Lutfan Lazuardi, Hari Kusnanto

Kesmas

Pengendalian tuberkulosis telah meningkatkan angka kesembuhan dan menyelamatkan banyak jiwa, tetapi kurang berhasil menurunkan insiden tuberkulosis. Oleh karena itu, pengendalian tuberkulosis menekankan pada kebijakan determinan sosial karena determinan sosial secara langsung dan melalui faktor risiko tuberkulosis berpengaruh terhadap tuberkulosis. Hasil telaah literatur menunjukkan bahwa stratifikasi determinan sosial menyebabkan clustering tuberkulosis, berupa pengelompokkan penderita tuberkulosis menurut lokasi geografis yang secara statistik signifikan. Pengetahuan tentang clustering sangat bermanfaat dalam pengendalian tuberkulosis, khususnya untuk menurunkan insiden tuberkulosis karena dapat memberikan informasi tentang lokasi populasi yang berisiko. Selain itu, telaah literatur menunjukkan bahwa implementasi analisis spasial memerlukan dukungan sumber daya yang tidak sedikit. Oleh …

Konseling Model Transteoritik Dalam Perubahan Perilaku Merokok Pada Remaja, Adhitya Mardhika Saputra, Noni Mardeka Sary

Kesmas

Perkembangan perokok di kalangan anak-anak dan remaja semakin meningkat, baik secara kuantitas maupun kualitas. Data Global Youth Tobacco Survey terakhir di tahun 2009, menunjukkan 20,3% anak sekolah 13 - 15 tahun merokok. Perokok pemula usia 10 - 14 tahun naik 2 kali lipat dalam 10 tahun terakhir dari 9,5% pada tahun 2001 menjadi 17,5% pada tahun 2010. Angka perokok pada usia remaja yang tinggi meningkatkan risiko penyakit. Berdasarkan penelitian, para perokok yang terus merokok dalam jangka panjang memiliki risiko kematian tiga kali lebih tinggi daripada mereka yang bukan perokok. Individu mulai merokok disebabkan oleh pengaruh lingkungan sosial, seperti teman-teman, orang …

Praktik Peracikan Puyer Untuk Anak Penderita Tuberkulosis Di Indonesia, Selma Siahaan, Ully Adhie Mulyani

Kesmas

Masih banyak ditemukan resep obat antituberkulosis anak dengan kombinasi beberapa obat dalam racikan puyer yang tidak sesuai standar program pemberantasan tuberkulosis (TB) paru Kementerian Kesehatan Republik Indonesia. Studi ini bertujuan untuk mengetahui situasi dan permasalahan berhubungan praktik peresepan puyer sebagai obat anti tuberkulosis (OAT). Pada periode Mei hingga Desember tahun 2009, penelitian diawali dengan pengukuran persentase peracikan OAT dalam bentuk puyer, dilanjutkan dengan penelitian kualitatif eksploratif. Data dikumpulkan dari rumah sakit, puskesmas, apotek dan dinas kesehatan di Jakarta, Bandung, Medan, dan Makassar. Pada tiap fasilitas kesehatan, 30 sampel resep pengobatan diambil untuk pasien tuberkulosis anak usia 1 - 12 tahun. …

Mikroorganisme Patogen Pada Feses Tikus, Dyah Widiastuti, Nova Pramestuti, Endang Setiyani, Harjianti Fajar Rahayu

Kesmas

Tikus liar dan domestikasi mempunyai potensi faktor risiko bagi kesehatan masyarakat. Mereka dapat membawa mikroorganisme yang dapat ditransmisi melalui kontak dengan urine maupun feses atau melalui ektoparasit yang ada di tubuh mereka. Pada penelitian ini, diamati prevalensi mikroorganisme zoonotik pada tikus yang tertangkap di Pasar Kota Kabupaten Banjarnegara. Bakteri Salmonella paratyphi B dan Salmonella paratyphi C menunjukkan prevalensi yang paling tinggi (masing-masing 20%). Spesies bakteri lain yang ditemukan antara lain Salmonella typhimurium, Citrotobacter, Citrotobacter frendii, Enterotobacter cloacae, Escherichia coli (E. coli) dan Proteus miriabilis. Hasil penelitian ini mengindikasikan bahwa tikus yang berada di pasar dapat berperan sebagai reservoir untuk berbagai …

Pemetaan Dan Analisis Faktor Risiko Leptospirosis, Dwi Sarwani Sri Rejeki, Sri Nurlaela, Devi Octaviana

Kesmas

Sampai dengan tahun 2013 dilaporkan ada 13 kasus leptospirosis di Kabupaten Banyumas.Terjadinya peningkatan kasus selama dua tahun terakhir perlu mendapat perhatian dari berbagai pihak agar kasus leptospirosis bisa segera ditangani. Tujuan penelitian ini adalah memetakan kasus leptospirosis dan menganalisis faktor risiko lingkungan dan perilaku yang memengaruhi leptospirosis. Penelitian ini menggunakan desain studi observasional kasus kontrol. Pengumpulan data dilakukan dengan wawancara, observasi, dan pengukuran. Analisis data menggunakan analisis spasial, analisis univariat, dan bivariat. Kasus adalah penderita leptospirosis berjumlah 13 orang dan kontrol adalah tetangga kasus yang tidak menderita leptospirosis berjumlah 52 orang. Hasil pemetaan menunjukkan kasus leptospirosis di Kabupaten Banyumas termasuk …

Hubungan Penggunaan Kontrasepsi Pil Dengan Usia Menopause, Fitriyani Fitriyani, Ratna Djuwita

Kesmas

Menopause merupakan menstruasi yang berhenti secara permanen yang disebabkan kehilangan fungsi folikel sel-sel telur. Wanita yang memasuki menopause mengalami penurunan hormon estrogen yang mengganggu aktivitas sehari-hari, bahkan menurunkan kualitas hidup. Penggunaan kontrasepsi pil berhubungan dengan penundaan usia dan keluhan menopause. Penelitian ini bertujuan mengetahui hubungan antara penggunaan kontrasepsi pil terhadap usia menopause. Penelitian ini menggunakan desain potong lintang. Populasi adalah wanita menopause di Pos Pembinaan Terpadu (Posbindu) Kota Depok. Sampel pada penelitian adalah wanita menopause yang berusia 45 - 60 tahun. Teknik pengambilan sampel secara purposive sampling subjek dengan besar sampel 407 orang. Analisis multivariat pada penelitian ini menggunakan cox …

Pendidikan Ibu Dan Durasi Pemberian Air Susu Ibu Dalam Peningkatan Kecerdasan Siswa Usia Sekolah Dasar, Maryam Said, Hadi Pratomo

Kesmas

Riwayat pemberian Air Susu Ibu (ASI), karakteristik ibu dan anak serta pola asuh berpengaruh terhadap kecerdasan anak. Penelitian ini bertujuan untuk mengetahui proporsi tingkat kecerdasan anak, riwayat pemberian ASI, karakteristik ibu dan anak, serta faktor dominan yang berhubungan dengan tingkat kecerdasan anak pada siswa SDSN Pekayon Jaya VI Kota Bekasi. Penelitian kuantitatif dengan desain potong lintang dengan metode systematic random sampling dengan jumlah sampel sebesar 166 responden (siswa/i yang berumur 7 - 9 tahun) beserta ibunya. Penelitian ini dilaksanakan pada bulan Mei 2013. Pada siswa dilakukan tes kecerdasan menggunakan tes Raven sedangkan ibunya mengisi kuesioner. Hasil penelitian menunjukkan tingkat kecerdasan …

Comparing Papanicolau Smear, Visual Inspection With Acetic Acid And Human Papillomavirus Cervical Cancer Screening Methods Among Hiv-Positive Women By Immune Status And Antiretroviral Therapy, Michael Chung, K. P. Mckenzie, H. D. Vuyst, B. A. Richardson, Farzana Rana, R. Pamnani, J. W. Njoroge, E. Nyongesa-Malava, S. R. Sakr, G. C. John-Stewart, N. R. Mugo

Internal Medicine, East Africa

Background: A rigorous comparison of cervical cancer screening methods utilizing data on immune status, antiretroviral therapy (ART) and colposcopy-directed biopsy has not been performed among HIV-positive women.

Methods: Between June and November 2009, 500 HIV-positive women were enrolled at an HIV treatment clinic in Nairobi, Kenya, and underwent Papanicolau (Pap) smear, visual inspection with acetic acid (VIA), human papillomavirus (HPV) and colposcopydirected biopsy (gold standard). Positive Pap smear (ASCUS, LSIL, HSIL), VIA, HPV and their combinations were compared with CIN2/3+. Sensitivity, specificity and AUC (sensitivity and 1-specificity) were compared using pairwise tests and multivariate logistic regression models that included age, …

Evolution Of The Pygmy Phenotype: Evidence Of Positive Selection From Genome-Wide Scans In African, Asian, And Melanesian Pygmies, Andrea Bamberg Migliano, Irene Gallego Romero, Mait Metspalu, Matthew Leavesley, Luca Pagani, Tiago Antao, Da-Wei Huang, Brad T. Sherman, Katharine Siddle, Clarissa Scholes, Georgi Hudjashov, Elton Kaitokai, Avis Babalu, Maggie Belatti, Alex Cagan, Bryony Hopkinshaw, Colin Shaw, Mari Nelis, Ene Metspalu, Reedik Mägi, Richard A. Lempicki, Richard Villems, Marta Mirazon Lahr, Toomis Kivisild

Human Biology

Human pygmy populations inhabit different regions of the world, from Africa to Melanesia. In Asia, short-statured populations are often referred to as "negritos." Their short stature has been interpreted as a consequence of thermoregulatory, nutritional, and/or locomotory adaptations to life in tropical forests. A more recent hypothesis proposes that their stature is the outcome of a life history trade-off in high-mortality environments, where early reproduction is favored and, consequently, early sexual maturation and early growth cessation have coevolved. Some serological evidence of deficiencies in the growth hormone/insulin-like growth factor axis have been previously associated with pygmies’ short stature. Using genome-wide …

Mount Pinatubo, Inflammatory Cytokines, And The Immunological Ecology Of Aeta Hunter-Gatherers, Robin M. Bernstein, Nathaniel J. Dominy

Human Biology

Early growth cessation and reproduction are predicted to maximize fitness under conditions of high adult mortality, factors that could explain the pygmy phenotype of many rainforest hunter-gatherers. This life-history hypothesis is elegant but contentious in part because it lacks a clear biological mechanism. One mechanism stems from the field of human immunological ecology and the concept of inflammation "memory" across the life cycle and into subsequent generations. Maternal exposures to disease can infl uence immunological cues present in breast milk; because maternal provisioning via lactation occurs during critical periods of development, it is plausible that these cues can also mediate …

Introduction: Revisiting The "Negrito" Hypothesis: A Transdisciplinary Approach To Human Prehistory In Southeast Asia, Phillip Endicott

Human Biology

The "negrito" hypothesis predicts that a shared phenotype among various contemporary groups of hunter-gatherers in Southeast Asia - dark skin, short stature, tight curly hair - is due to common descent from a region-wide, pre-Neolithic substrate of humanity. The alternative is that their distinctive phenotype results from convergent evolution. The core issues of the negrito hypothesis are today more relevant than ever to studies of human evolution, including the out-of-Africa migration, admixture with Denisovans, and the effects of environment and ecology on life-history traits. Understanding the current distribution of the negrito phenotype dictates a wide-ranging remit for study, including the …

The Cord (November 27, 2013)

The Cord

No abstract provided.

Personal And Household Hygiene, Environmental Contamination, And Health In Undergraduate Residence Halls In New York City, 2011, Benjamin A. Miko, Bevin Cohen, Katharine Haxall, Laurie Conway, Nicole Kelly, Dianne Stare, Christina Tropiano, Allan Gilman, Samuel L. Seward, Elaine Larson

Publications and Research

Background While several studies have documented the importance of hand washing in the university setting, the added role of environmental hygiene remains poorly understood. The purpose of this study was to characterize the personal and environmental hygiene habits of college students, define the determinants of hygiene in this population, and assess the relationship between reported hygiene behaviors, environmental contamination, and health status. Methods 501 undergraduate students completed a previously validated survey assessing baseline demographics, hygiene habits, determinants of hygiene, and health status. Sixty survey respondents had microbiological samples taken from eight standardized surfaces in their dormitory environment. Bacterial contamination was …

Correction: Association Of Pol Diversity With Antiretroviral Atment Outcomes Among Hiv-Infected African Children, Iris Chen, Leila Khaki, Jane C. Lindsey, Carrie Fry, Matthew M. Cousins, Robert F. Siliciano, Avy Violari, Paul Palumbo, Susan H. Eshleman

Dartmouth Scholarship

Background: In HIV-infected children, viral diversity tends to increase with age in the absence of antiretroviral treatment (ART). We measured HIV diversity in African children (ages 6–36 months) enrolled in a randomized clinical trial comparing two ART regimens (Cohort I of the P1060 trial). Children in this cohort were exposed to single dose nevirapine (sdNVP) at birth. Methods: HIV diversity was measured retrospectively using a high resolution melting (HRM) diversity assay. Samples were obtained from 139 children at the enrollment visit prior to ART initiation. Six regions of the HIV genome were analyzed: two in gag , one in pol …