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Networking Customary Law, Scott Sullivan

Journal Articles

In United States v. Jones, the U.S. Supreme Court considered whether gathering four weeks of GPS information capturing a suspect’s movement on public roads constituted an unlawful search under the Fourth Amendment of the U.S. Constitution.

In two separate concurring opinions, Justices Alito and Sotomayor rejected the notion that all of a citizen’s movements in public were free from the Amendment’s protection. A unifying theme for both justices was the power of contemporary technology to aggregate isolated acts into a comprehensive knowledge of a person’s private life. Justice Alito writing on behalf of four Justices notes that, over time, the …

Calcifying Nanoparticles As Novel Etiologic Agents Of Idiopathic Preterm Birth And Preterm Premature Rupture Of The Membranes, Lydia Shook

Yale Medicine Thesis Digital Library

Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality. In many cases, preterm birth is preceded by preterm premature rupture of the membranes (PPROM) without any identifiable cause. Pathological calcification, i.e. the deposition of hydroxyapatite (HA) in non-skeletal tissue, has been implicated in degenerative diseases of soft tissue, such as atherosclerosis. Multiple pathogenic mechanisms have been described, including the aberrant aggregation of HA into calcifying nanoparticles (CNPs) and the HA-induced differentiation of mesenchymal cells into osteoblasts in a process called ectopic osteogenesis. The objective of this thesis was to explore the possibility that CNPs form in human …

Urinary Biomarkers And Association With Recovery From Severe Aki, Rahul Agarwal

Yale Medicine Thesis Digital Library

Few studies have examined the ability of urinary biomarkers to associate with recovery from acute kidney injury (AKI), a common complication for hospitalized patients that is independently associated with severe morbidity and mortality. We hypothesized that urinary biomarkers of kidney injury (NGAL, IL-18) or repair (YKL-40) would be associated with renal recovery in patients with severe AKI.

We prospectively enrolled 48 patients admitted at Yale New Haven Hospital with severe AKI (AKIN Stage 3). Daily morning urine samples were collected (until recovery up to max of 9 days). Levels of urinary YKL-40, NGAL, and IL-18 were measured. The primary exposures …

Brain Derived Neurotrophic Factor: A Foray Into Predicting Neonatal Outcomes In Premature Infants, Vladimir Vladislav Glinskii

Yale Medicine Thesis Digital Library

The need to accurately predict the ability of a prematurely born infant to recover from hypoxia induced damage associated with prematurity is rooted in our need to develop better interventions, with fewer side-effects, with which to treat these complicated patients. Previous work done in murine models mimicking hypoxia induced damage and its neurological sequelae have suggested hypoxia induced factor-1alpha; (HIF-1alpha), and its downstream effector molecules, brain derived neurotrophic factor (BDNF) and stromal derived factor-1 (SDF-1), may play an integral role in protecting the developing brain from the deleterious effects of low O2. Moreover, a number of single nucleotide polymorphisms (SNPs) …

Altered Circulating Follicular Helper T Cell Phenotype In Systemic Lupus Erythematosus, Hsi-En Ho

Yale Medicine Thesis Digital Library

Autoreactive B cells in Systemic Lupus Erythematosus (SLE) undergo autoantigen selection, suggesting a requirement for germinal center follicular helper T (Tfh) cells in their maturation. However, evidence for dysregulation of Tfh cells in SLE and their contribution to disease activity remains unclear. Recently, blood CXCR5hi CD4 T cells, a heterogeneous pool consisting of functionally distinct Th1-, Th2-, Th17-like subsets, have been proposed to be the circulating counterpart of Tfh cells. The purpose of this study was to examine the hypothesis that Tfh dysregulation, as reflected in altered phenotype of blood CXCR5hi population, was associated with SLE disease activity. Blood samples …

Spatial Distribution Of Alitta Virens And Clymenella Torquata With Respect To Rigid Boundaries In Mud And Sand, Kevin T. Du Clos, Sara M. Lindsay, Peter A. Jumars

Journal of Marine Research

Recent advances in understanding of sediment material properties and of burrowing mechanics suggest likely differences in the behavior of organisms burrowing in mud and sand. The path of least resistance in the mud may lead an infaunal organism to burrow along a rigid wall. By contrast, in sand, force chains may prevent a burrowing organism from reaching a rigid wall. Burrowing in mud occurs primarily by the propagation of cracks. Cracks, and hence burrows, tend to propagate along rigid walls. In sand, force chains comprise collections of particles that experience much more stress than their neighbors. Stress chains tend to …

We Are Always Already Imprisoned: Hyper-Incarceration And Black Male Identity Performance, Frank Rudy Cooper

Scholarly Works

In this Essay, Professor Frank Rudy Cooper recenters the experiences of men of color, particularly those of black men, in light of Reagan's War on Drugs and recent scholarship illustrating the over-representation of men of color in prison for petty drug use. The mainstream's depiction of black men as always already imprisoned disciplines us into the never-finished quest to prove we are a "Good Black Man," rather than a "Bad Black Man." In order to propose greater empathy for black men's imprisonment, this article proceeds in the following manner. In Part I, Professor Cooper sets the stage for considering the …

Nfib V. Sebelius: Proportionality In The Exercise Of Congressional Power, David Orentlicher

Scholarly Works

With its opinion on the constitutionality of the Affordable Care Act (ACA), the U.S. Supreme Court sparked much discussion regarding the implications of the case for other federal statutes. In particular, scholars have debated the significance of the Court's recognition of an anticoercion limit to the Spending Clause power.

When it recognized an anticoercion limit for the ACA's Medicaid expansion, the Court left considerable uncertainty as to the parameters of that limit. This essay sketches out one valuable and very plausible interpretation of the Court's new anticoercion principle. It also indicates how this new principle can address a long-standing problem …

From “Food Miles” To “Moneyball”: How We Should Be Thinking About Food And Climate, Bret C. Birdsong

Scholarly Works

Since Michael Pollan popularized the push to eat local food in his bestseller, The Omnivore’s Dilemma, the concept of “food miles” has been something of a rallying cry and an organizing principle in the marketing of the local food movement. Among locavores and their sympathizers, the term seems to encapsulate all that is wrong with the food system. Fresh grapes from Chile make their way to supermarkets from Maine to Minnesota, and even California. Major food conglomerates process commodity ingredients like corn, soy, and wheat into packaged food that travels across the country and across oceans before landing on …

Of Carts And Horses: Organizing Remedies For The Classroom, Elaine W. Shoben

Scholarly Works

No abstract provided.

Where Do The Prophets Stand?: Hamdi, Myth And The Master's Tools, Linda H. Edwards

Scholarly Works

No abstract provided.

Medicine@Yale March 2013 Volume 9, Issue 1, Yale School Of Medicine Office Of Communications

Medicine@Yale - development newsletter

Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.

Regulation Of Alpha Synuclein Following Chronic Methamphetamine Administration In Guinea Pigs: Correlation With Memory And Synaptic Plasticity, Adnouse Blanc

PCOM Biomedical Studies Student Scholarship

Methamphetamine (METH) is a highly addictive drug of abuse that has a severe impact on neuronal changes in the brain including modulations of plasticity, cognitive dysfunction, as well as memory impairment. These changes can be seen as modifications in the expression of biochemical markers associated with synaptic plasticity. One such marker associated with memory impairment is alpha synuclein (α-syn). Alteration of α-syn expression has been linked to memory impairment in patients with Alzheimer’s disease (AD) and Parkinson’s disease (PD). Here we assess the effect of chronic METH treatment in correlation to cognitive functions.

Twenty-nine guinea pigs (male, 150-250 g) were …

Molecular Mechanisms Related To Endotoxemia In Primary Human Cardiomyocytes In Culture, Atijah J. Collins

PCOM Biomedical Studies Student Scholarship

Cardiovascular disease (CVD) is the leading cause of death in the United States and has been for the past 80 years. Development of novel therapeutic agents to address the large number of CVD deaths requires an in depth understanding of the structural and functional properties of human cardiomyocytes. Over the last few years we have been developing an in vitro paradigm to assess molecular cardiodynamics in Primary Human Cardiomyocyte in culture (PHCC). We tested the hypothesis whether endotoxemia would exhibit a marked decrease in contractile proteins and cause apoptosis in PHCC. In the current series of experiments, we induced endotoxemia …

When Certainty Dissolves Into Probability: A Legal Vision Of Toxic Causation For The Post-Genomic Era, Steve C. Gold

Washington and Lee Law Review

Proof of causation in toxic torts has presented persistent problems for the legal system, because the probabilities that science can know fit poorly with the demands for particularistic proof imposed by the law’s deterministic model of causation. Some scholars have hoped that genomic and molecular information will at last provide scientific certainty—definitive, individualized proof of toxic causation. This Article argues that the opposite is true. Scientific research will increasingly elucidate the ways in which environmental exposures and human genes interact to produce disease, but this deeper knowledge will extend rather than resolve the problem of causal indeterminacy in toxic torts. …

Yale School Of Nursing : Celebrating 90 Years Of Excellence ; Ysn: A Brief History, Helen Varney Burst Cnm, Msn, Dhl (Hon.), Facnm

Yale School of Nursing Alumni Newsletters and Magazines

This book is a brief history of Yale University's School of Nursing for the past 90 years, from 1923-2013.

The Moral Trauma Of America's Warriors: Why We Must Treat Combat Posttraumatic Stress Disorder As A Bio-Psycho-Social-Spiritual Phenomenon, E. Ann Jeschke

Nova Law Review

No abstract provided.

The Aftermath Of International Conflicts: Veterans Domestic Violence Cases And Veterans Treatment Courts, Linda J. Fresneda

Nova Law Review

No abstract provided.

Reconstructing Fuller's Argument Against Legal Positivism, Dan Priel

Articles & Book Chapters

No abstract provided.

The Indirect Influence Of Politics On Tort Liability Of Public Authorities In English Law, Dan Priel

Articles & Book Chapters

No abstract provided.

Validation Of The Ottawa Ankle Rules At A Tertiary Teaching Hospital: A Cross-Sectional Study, Mark Karanja Tharao

Master of Medicine in General Surgery

Introduction: Ankle joint and foot injuries are among the commonest injuries seen at the Accident and Emergency Department of any hospital. Within the United States it is the second most common musculoskeletal injury seen by physicians. Assessment of these injuries is done clinically and when deemed necessary a radiograph is requested. Studies have shown that radiographs are ordered in over 95% of cases yet the prevalence of fractures is in the range of 15-20%. This means that more than 80% of patients are exposed to unnecessary radiation. The Ottawa ankle rules have been designed to reduce the need for performing …

Ships Of The Fleet: An Essay On The Weltanschauung Of The Apostolate And The Mission Of The Spirit, Art Mcphee

The Asbury Journal

In honor of Bishop Sundo Kim

This paper was presented in Asbury Theological Seminary, on November 14, 2012, at Dr. Art McPhee’s installation in the Sundo Kim Chair for Evangelism and Practical Theology Expertise: Evangelization Studies. In this essay, he explores the role of the Holy Spirit in mission and evangelism as an often-overlooked subject in the Church today.

Understanding Christian Perfection And Its Struggle With Antinomianism, Victoria L. Campbell

The Asbury Journal

Every so often, a professor at Asbury Theological Seminary will notice a current student with exceptional promise. The Asbury Journal wants to help highlight the work of rising academics by publishing works from such students. This paper is an example of such a work, brought to the attention of the editor by Dr. Larry Wood.

Much of the confusion regarding John Wesley’s phrase, Christian perfection, comes from the western tendency to define “perfection” as a state of infallibility (from the Latin perfectio) rather than a process of spiritual maturing based upon the Greek word for perfection, teleios (Matthew …

The Rise And Decline Of The Church Growth Movement, Elmer Towns

Great Commission Research Journal

Dr. Towns surveys the movements and personalities that brought the Church Growth Movement into being and gave it a focus in the American church scene. Then he discusses the several accomplishments in its golden age of influence. After 20 years of ministry in various areas, the Church Growth Movement began to decline as evidenced by nine trends surveyed by Dr. Towns. Then he noted seven continuing influences of the Church Growth Movement on today’s church culture. Finally he reminds the reader of what God can do through the church and that God is still using churches today.

How Culture Shapes Personality: A Preliminary Study, Hing Man Amy Wong

Theses and Dissertations

The purpose of this study was to explore the relevance of a collectivistic personality attribute indigenous to the Chinese culture to non-Asian collectivistic cultures. To measure this attribute, the CPAI-2 Interpersonal Relatedness factor scales were administered to current college students who self-identified as Mexican American, Chinese American, or Caucasian. Only less acculturated Mexican American and Chinese American participants, as measured by the ARMSA-II or SL-ASIA, respectively, were included in the analysis. Although the Mexican American and Chinese American participants did not significantly differ from one another, these two groups did significantly differ from the Caucasian participants on two scales, Traditionalism-Modernity …

Maternal Hydration And Infant Weight: A Case-Control Study In Breastfeeding Infants Delivered By Cesarean Section, Diane J. Thulier

Open Access Dissertations

Growing evidence suggests that infants may experience increased weight loss due to maternal medical interventions during labor such as intravenous fluid hydration. When breast fed infants lose ≥ 7% of their birth weight, formula supplementation is often initiated. Formula supplementation is a variable unequivocally associated with shorter breastfeeding duration. Supplementation should not be initiated if the cause of infant weight loss is unrelated to breastfeeding adequacy. The purpose of this study is to examine the impact of intrapartum maternal hydration and regional anesthesia on infant weight.

A retrospective, case-control research study was designed. Data was collected from maternal and infant …

Seasonal Particle And Carbon Dynamics In The Eastern Bering Sea, Matthew S. Baumann

Open Access Dissertations

The ocean margins of high-latitude seas, such as the eastern Bering Sea, are recognized as important areas for the enhanced scavenging removal of particle reactive chemicals and for the potential to sequester atmospheric carbon dioxide via photosynthetic conversion to biogenic particles and subsequent downward particle transport to deeper waters. This region is expected to warm in the future, and with the warming will come a reduction in the extent and duration of seasonal sea-ice. This physical process exerts an important control on the timing, location, and magnitude of the spring primary production bloom. Within the context that 2008-2010 are characterized …

Sequence Effects On The Repair And Replication Of Arylamine-Dna Adducts, Vipin Jain

Open Access Dissertations

Cancer is a collection of diseases defined by uncontrolled cell growth and dissemination of abnormal cells. It is the second most deadly disease in the United States. Exposure to chemicals, both endogeneous and exogeneous is one of the major causes of cancer initiation. The role of chemicals in carcinogenesis was observed back in the eighteenth century when surgeon Pott observed a large number of scrotal cancer cases in chimney sweeps and associated it with to the soot exposure. However, research in the field of chemical carcinogenesis was renewed when Yamagawa and Ichikawa reported the development of malignant tumor on the …

Application Of Silver Nanoparticles In Drinking Water Purification, Hongyin Zhang

Open Access Dissertations

Nanotechnology is an emerging and fast-growing technology. Currently, there are more than 1,317 nanotechnology-based products on the market. Silver nanoparticles account for more than 23% of all nano-products. The extensive application of the silver nanoparticle (AgNP) results in their inevitable release into the environment. Silver nanoparticles are known as excellent antimicrobial agents, and therefore they could be used as alternative disinfectant agents. On the other hand, released silver nanoparticles could pose a threat to naturally occurring microorganisms.

In Chapter 1, we introduce the background information on the environmental fate, toxicological effects, and application of AgNP and review the current knowledge …

The Impact Of Predator-Prey Relationships On The Formation Of Harmful Algal Blooms In Heterosigma Akashiwo, Elizabeth L. Harvey

Open Access Dissertations

Heterotrophic protists are the primary grazers of phytoplankton in the marine environment, and changes in the rates of consumption will influence phytoplankton abundance, community composition, and ecological function. The objective of this research was to investigate the influence of predators on the formation and promotion of harmful algal blooms (HABs), specifically blooms of the toxic raphidophyte alga, Heterosigma akashiwo. To observe microscopic predator-prey interactions and their macroscopic distributions, video and image analysis were used to simultaneously quantify population distributions and individual 3D movements of both protistan predators and prey cells in laboratory tanks with realistic salinity structures. In behavioral experiments, …