Digital Commons Network^™

July 6, 2012 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Assessment Of A Microbicide Candidate Among A Diverse Cohort Of Urban Southern Us Women And Their Male Sexual Partners, Paula M. Frew, Kimberly Parker, Takeia Horton, Brooke Hixson, Lisa Flowers, Frances Priddy, Lisa Grohskopf, Christine Mauck, Kimberly Workowski

Environmental & Global Health Faculty Research

Background: This mixed methods study reports on product acceptance from a Phase I clinical trial of a candidate non-nucleoside reverse transcriptase inhibitor (NNRTI) vaginal microbicide product (UC781). The product was evaluated in the context of a Phase I clinical trial in an area characterized by high HIV prevalence among minority women. The findings will inform the development of an acceptable microbicide that will address the needs of diverse women and their partners. Methods: This is a mixed methods study of 34 racially and ethnically diverse female participants and 10 male partners in Atlanta, Georgia. Chi-square tests for marginal homogeneity and …

A Case Of Otogenic Tetanus., Mohammad Adeel, Shaheryar Ahmed Rajput, Muhammad Sohail Awan, Asif Arain

Section of Otolaryngology, Head & Neck Surgery

The authors are presenting our experience of managing an interesting case of a 12-year-old girl who presented to our clinic with otorrhea for 3 months and trismus for 1 week. Examination showed bilateral ear discharge with central perforations in tympanic membranes, palatal paralysis and trismus. Systemic examination revealed only mild stiffness of hand muscles. CT-scan head and neck was done to look for intracranial complications of otitis media. However, it revealed only decreased pneumatisation of mastoid cells. She was admitted in the hospital and started on intravenous and local antibiotics after sending ear swab and blood cultures. But she showed …

Responsiveness Of The Federal Health System To The Needs Of 18-45 Year Old Adults With Physical Disabilities In Islamabad, Pakistan, Shaista Habibullah

USF Tampa Graduate Theses and Dissertations

Abstract

The health system has been defined as all people, institutions and resources that undertake actions with the primary intent of improving health, while responsiveness of the health system refers to its objective of responding to the legitimate expectations of the population it serves. Although responsiveness is a non-health objective of the health system, it affects the health status of the population by influencing treatment compliance, patient-provider communication and health services utilization. Furthermore, responsiveness has a fundamental value as it concerns basic human rights of the individuals being served by the health system.

This study was undertaken to determine how …

Law In The Book And Law In Practice: Criminal Liability Over Vessel-Source Marine Pollution In China, Nengye Liu

Global Environmental Law at a Crossroads

Nowadays, criminal liability over vessel-source pollution is a debatable issue worldwide. For example, after Erika and Prestige oil tanker spill disasters, the EU adopted Directive 2005/35/EC, which imposes criminal liability over vessel-source pollution. This raised the Intertanko Case in the European Court of Justice. The shipping industry tried to challenge the legality of Directive 2005/35/EC under international law.

China is now a great shipping power as well as the second largest seafarers supplier in the world. Meanwhile, vast sea areas under China’s jurisdiction are under threat of vessel-source pollution. This presentation addresses criminal liability over vessel-source pollution in China. Relevant …

Bjc Today

BJC Today

No abstract provided.

Types Of Bacteria Associated With Neonatal Sepsis In Al-Thawra University Hospital, Sana’A, Yemen, And Their Antimicrobial Profile, Hassan A. Al-Shamahy, Amal A. Sabrah, Abdul Baki Naser, Samarih M.

Sultan Qaboos University Medical Journal

Objectives: This study was undertaken to investigate the organisms causing sepsis in the Neonatal Unit at Al-Thawra Hospital, Sana’a, Yemen, determine their resistance to antibiotics, and recommend policy for empirical treatment. Methods: A total of 158 neonates having one or more signs of sepsis, and aged from 0 to 28 days, were enrolled in this study. A blood sample was taken from each subject, cultured, and then antibacterial susceptibility tests were performed for isolates. Results: 90 (57%) cases yielded positive cultures. Early-onset sepsis showed higher positive culture results (61.7%) than late-onset sepsis (32%). Significant positive culture results were found among …

Misdiagnosis Of Myasthenia Gravis And Subsequent Clinical Implication : A Case Report And Review Of Literature, Abdullah Al-Asmi, Ramachandiran Nandhagopal, P C. Gujjar, Arunodaya

Sultan Qaboos University Medical Journal

The autoimmune disease, myasthenia gravis (MG), can mimic a variety of neurological disorders leading to a delay in diagnosis and treatment. On occasions, misdiagnosis of MG could lead to unnecessary and potentially harmful therapeutic interventions. We report on a 12 year-old boy, in whom MG was mistaken for meningitic sequelae and subsequently for critical neuropathy/myopathy resulting in considerable morbidity for nearly a decade. Subsequent correct diagnosis and optimal management resulted in significant improvement in his functional status. We discuss the importance of considering MG as one of the potential differential diagnoses among cases of recurrent respiratory pump failure, or unexplained …

Infective Endocarditis Of The Aortic Valve Caused By Pseudomonas Aeruginosa And Treated Medically In A Patient On Haemodialysis, Kowthar S. Hassan, Dawood Al-Riyami

Sultan Qaboos University Medical Journal

Infective endocarditis (IE) in patients on dialysis is a serious infection with a high mortality rate. It is usually caused by Gram positive bacteria with Gram negative organisms being relatively rare as a cause. Recommended treatment usually involves surgical valve replacement and the extended use of antibiotics. Successful treatment with antibiotics alone is rare. We report a case of IE caused by Pseudomonas aeruginosa in a patient on dialysis treated solely with antibiotics.

A Structural Perspective Of Antibody Neutralization Of Dengue Virus, Stephen Kyle Austin

All Theses and Dissertations (ETDs)

The four dengue viruses: DENV) are mosquito-borne flaviviruses and are considered the world's most significant arboviruses in terms of worldwide disease burden. Symptoms of dengue disease are classified into dengue fever, a mild, febrile illness, and the potentially fatal severe dengue, which can include hemorrhaging and shock. Antibody protection against DENV correlates with the production of neutralizing antibodies against the envelope: E) glycoprotein.

To understand the role of antibodies in DENV infection, we sought to dissect the relationship between epitope and function. Virologic studies had identified that the most potently neutralizing antibodies are against domain III: DIII) of the E …

Efficacy Comparison Of Various Pcr Master Mixes And Thermal Cycling Parameters For Detection Of Brucella Abortus In Multiplex Assays, Kevin J. Testo, Jason A. Olivas, Alda C. Carrillo, Pejman Naraghi-Arani

STAR Program Research Presentations

Diagnostic testing for bioterrorism agents in food is essential for the safety and welfare of the general populace. Multiplex assays provide the means to test for multiple pathogen signatures with a single polymerase chain reaction (PCR) test. PCR, Luminex xMAP ® infrared fluorophore bead technology, and flow cytometry, multiplex diagnostic assays are incredibly specific and sensitive to highly conserved regions at various loci in a microbe’s genome. In order to increase the effectiveness of the PCR and the resulting fluorescent response of the beads, different PCR master mix commercial kits were compared to the standard AgPath RT-PCR mix. This study …

Newsletter Summer 2012

Newsletter

No abstract provided.

Clinic Connection: Summer 2012, Centracare Clinic

Clinic Connection

• President’s Message: "CentraCare strives for cultural competency and workforce diversity"
• Pre-visit planning increases quality of time with patients
• Radiofrequency ablation treats Barrett’s esophagus
• WPS Medicare Part B changes HPI reporting
• Keeping pediatric cancer care closer to home
• Gain the collaboration you desire through service

Com Outlook Summer 2012, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Gastrointestinal Cell Mediated Immunity And The Microsporidia, Magali M. Moretto, Imtiaz A. Khan, Louis M. Weiss

Microbiology, Immunology, and Tropical Medicine Faculty Publications

No abstract provided.

Germline Transgenesis And Insertional Mutagenesis In Schistosoma Mansoni Mediated By Murine Leukemia Virus, Gabriel Rinaldi, Sabine E. Eckert, Isheng J. Tsai, Suttas Suttiprapa, Kristine J. Kines, Jose F. Tort, Victoria H. Mann, Daniel J. Turner, Matthew Berriman, Paul J. Brindley

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Functional studies will facilitate characterization of role and essentiality of newly available genome sequences of the human schistosomes, Schistosoma mansoni, S. japonicum and S. haematobium. To develop transgenesis as a functional approach for these pathogens, we previously demonstrated that pseudotyped murine leukemia virus (MLV) can transduce schistosomes leading to chromosomal integration of reporter transgenes and short hairpin RNA cassettes. Here we investigated vertical transmission of transgenes through the developmental cycle of S. mansoni after introducing transgenes into eggs. Although MLV infection of schistosome eggs from mouse livers was efficient in terms of snail infectivity, >10-fold higher transgene copy …

Is Human Immunodeficiency Virus Infection A Risk Factor For Strongyloides Stercoralis Hyperinfection And Dissemination, Marc O. Siegel, Gary L. Simon

Medicine Faculty Publications

No abstract provided.

Systemic Sclerosis Disease Modification Clinical Trials Design: Quo Vadis?, Fabian A. Mendoza, Md, Lynette L Keyes-Elstein, Sergio A. Jimenez

Scleroderma Center Faculty Papers

The purpose of this manuscript is to discuss relevant aspects of clinical trials for Systemic Sclerosis (SSc) and to identify important considerations for the design of SSc disease modification clinical trials. Placebo randomized controlled trials with appropriate identification of SSc patients with diffuse progressive SSc skin involvement of recent onset, along with a rescue strategy for patients with worsening lung and skin involvement are suggested. If change in skin thickening is a major outcome of the study, the selection of patients with recent onset of disease and a predetermined degree of skin involvement are crucial requirements. The trial duration should …

Shamans As Healers, Counselors, And Psychotherapists, Stanley Krippner

International Journal of Transpersonal Studies

Shamanic models of healing, counseling, and psychotherapy differ from Western models in that

they emphasize closeness to the natural world as well as to one’s body and life’s spiritual dimensions.

Shamanic practices reflect the ideals of harmony and knowledge. In shamanism, there is no division

between “mind” and “body,” hence what Westerners refer to as “mental illness” is seen as part of

the total client being treated by a shaman, a perspective that often includes the client’s family,

community, and the world of “spirits.”

"Re-Redefining" International Securing: Bringing Intent Back In, Nicholas D. Anderson

Josef Korbel Journal of Advanced International Studies

The tectonic geopolitical shifts that have taken place since the end of the Cold War have led many to put forth a need to rethink and revise the concept of international security. The traditional definition, they assert, is no longer sufficient in the face of the modern era’s most pressing security issues and threats. What are and will be the distinguishing features of international security problems? What should be considered an international security issue, and what should not? How can “international security” or “international security issue” be defined to allow academics and policymakers to most capably think about and deal …

Scwds Briefs: Volume 28, Number 2 (July 2012), Jeanenne Brewton, Michael J. Yabsley

Southeastern Cooperative Wildlife Disease Study: Publications

CWD News, July 2012

Does Heat + Drought = HD?

Cats on Candid Camera

Gray Bats and WNS

California or Bust

Recent SCWDS Publications Available

The Accelerator, Volume 5 Issue 10, Summer 2012, Christa Santos

The Accelerator

No abstract provided.

Not Congruent But Quite Complementary: U.S. And Chinese Approaches To Nontraditional Security, Lyle J. Goldstein

CMSI Red Books

U.S.-China relations, difficult in the best of times, have lurched in a dangerous direction since 2009. Against the backdrop of a weakened global economy and sharpened ideological tensions, there has been a disturbing new atmosphere of crisis in East Asia over the last two years, with incidents occurring in greater frequency and sowing serious doubts about the sustainability of the "long peace" that this region has enjoyed for decades. Indeed, any one of the following incidents could have escalated into a serious regional crisis: the sinking of the South Korean frigate Cheonan; the collision between a Japanese coast guard …

The Effects Of Genetic Ancestry And Sociocultural Factors On Pulmonary Tuberculosis Susceptibility In Northeastern Mexico, Bonnie Nadyne Young

Anthropology ETDs

Genetic and environmental factors contribute to variation in tuberculosis (TB) disease risk among individuals in the Americas, although the relative contribution of each of these factors remains unclear. Genetic ancestry may serve as a proxy for underlying genetic differences in TB risk between the European, Native American, and African groups that formed many populations in the Americas, but this has never been tested. Such tests are complicated by the fact that genetic ancestry and important potential social predictors of TB are usually confounded. The urban center of Nuevo León, the Monterrey Metropolitan Area (MMA), presents a unique setting to tease …

Combining Socio-Economic And Ecological Modelling To Inform Natural Resource Management Strategies, Johannes P. M. Heinonen, Justin M. J. Travis, Steve M. Redpath, Michelle A. Pinard

International Congress on Environmental Modelling and Software

Effective management of natural resources requires understanding both the dynamics of the natural systems being subjected to management and the decision-making behaviour of stakeholders who are involved in the management process. We suggest that simulation modelling techniques can provide a powerful method platform for the transdisciplinary integration of ecological, economic and sociological aspects that is needed for exploring the likely outcomes of different management approaches and options. A concise review of existing literature on ecological and socio-economic modelling and approaches at the interface of these fields is presented followed by a framework coupling an individual-based ecological model with an agent-based …

A Computer System For Forecasting Malaria Epidemic Risk Using Remotely- Sensed Environmental Data, Michael C. Wimberly, Ting-Wu Chuang, Geoffrey M. Henebry, Yi Liu, Alemayehu Midekisa, Paulos Semuniguse, Gabriel Senay

International Congress on Environmental Modelling and Software

Epidemic malaria is a major public health problem in the highlands of East Africa. Identifying the climatic triggers that increase malaria risk affords a basis for developing environmentally-driven early warning systems. Satellite remote sensing provides a wide range of environmental metrics that are sensitive to temperature, rainfall, and other climatic variables. The goals of this study were to develop a computer application for automatically acquiring and processing remote sensing data, and to test the utility of these data for modelling and forecasting malaria epidemics in the Amhara region of Ethiopia. The application was programmed using JAVA for user interface development …

Species Distribution Modelling And Open Source Gis: Why Are They Still So Loosely Connected?, Anne Ghisla, Duccio Rocchini, Markus Neteler, Michael Forster, Birgit Kleinschmit

International Congress on Environmental Modelling and Software

Species Distribution Models (SDMs) are correlative models that use environmental and/or geographical information to explain patterns of species occurrences. Those models are being used in various fields including climate change, invasive species research, evolutionary biology and epidemiology. Thanks to the availability of increasing computational resources, new methods continue to be developed. However, software packages that include the SDM algorithms usually focus on one or few methods, and have different degrees of integration with other geographical and statistical software. Specifically, SDM implementations are often standalone programs developed by university laboratories, either as extensions to statistical software. In few cases they are …

Checkup, Lehigh Valley Health Network

Checkup

No abstract provided.

Expanding Horizons: Scientific Frontiers, Legal Regulation And Globalization, Belinda Bennett

Indiana Journal of Global Legal Studies

In the six decades since the discovery of the double helix structure of DNA by Watson and Crick in 1953, developments in genetic science have transformed our understanding of human health and disease. These developments, along with those in other areas such as computer science, biotechnology, and nanotechnology, have opened exciting new possibilities for the future. In addition, the increasing trend for technologies to converge and build upon each other potentially increases the pace of change, constantly expanding the boundaries of the scientific frontier. At the same time, however, scientific advances are often accompanied by public unease over the potential …