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Hypoplastic Right-Heart Syndrome Presenting As Multiple Miscarriages, Chadi Dib, Philip A Araoz, Norman P Davies, Joseph A Dearani, Naser M Ammash

The Texas Heart Institute Journal

Reversible causes of miscarriage are many, but they affect only 1% of women who are trying to conceive. Herein, we describe the case of a 23-year-old woman who presented for evaluation of repeated miscarriages and was found to have hypoxemia and erythrocytosis. Further evaluation revealed hypoplastic right-heart syndrome with an intracardiac shunt. She underwent hybrid repair with pulmonary valve balloon valvuloplasty, followed by surgery to perform atrial septal defect closure and a Glenn anastomosis. The erythrocytosis and hypoxemia resolved, and she was able to conceive and deliver a healthy baby at term 2 years later.

This is a unique case …

Species Identification Of Invasive Yeasts Including Candida In Pakistan: Limitations Of Phenotypic Methods, Joveria Farooqi, Kauser Jabeen, Noureen Saeed, Afia Zafar, Mary Eleanor Brandt, Rumina Hasan

Department of Pathology and Laboratory Medicine

Objective: To compare phenotypic and genotypic methods of yeast identification. Methods: The in-vitro cross-sectional study was conducted from January 2006 to May 2009. Invasive yeasts isolated at the clinical microbiology laboratory at the Aga Khan University (AKU), Karachi, Pakistan, were identified. Speciation by phenotypic and molecular methods was compared. All yeasts isolated during the study period from blood and other invasive sites were identified using standard methods. Isolates were shipped to Mycotic Diseases Branch, Centres for Disease Control and Prevention, Atlanta, Georgia, USA, for identification by Luminex flow cytometric multianalyte profiling (xMAP) system. Ribosomal ITS2 DNA sequencing was performed …

Admonitions Or Accountability?: U.S. Implementation Of The Hague Adoption Convention Requirements For The Collection And Disclosure Of Medical And Social History Of Transnationally Adopted Children, Marianne Blair

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.

Evidence-Based Approaches To Protecting Adolescent Girls At Risk Of Hiv, Judith Bruce, Miriam Temin, Kelly Hallman

Adolescents and Young People

No abstract provided.

What Does The ¹⁴C Method For Estimating Photosynthetic Rates In The Ocean Really Measure?, Shaofeng Pei

LSU Doctoral Dissertations

The ¹⁴C method has been used extensively by both limnologists and oceanographers to measure photosynthetic rates in aquatic systems, and the large database of ¹⁴C measurements that now exists is the ground truth with which satellite algorithms for estimating marine photosynthetic rates on a basin and global scale have been calibrated. However, disconcerting uncertainties still remain with respect to whether and under what circumstances the ¹⁴C method provides an estimate of net or gross photosynthesis, or something in between. My study combined batch and continuous culture studies to clarify this ambiguous issue. The batch culture work with …

Single-Molecule Detection Of Molecular Beacons Generated From Ldr On Thermoplastic Microfluidic Device For Bioanalysis, Zhiyong Peng

LSU Doctoral Dissertations

Current clinical techniques for nucleic acid detection and analysis often involve PCR, lacking adequate specificity or sensitivity to meet the stringent requirements in certain applications. This research aims to develop an innovative molecular assay and the associated hardware to rapidly signal the presence of certain targets using reporter sequence found in their genome without requiring PCR. This assay coupled the sensitivity of single-pair fluorescence resonance energy transfer (spFRET) with the specificity of ligase detection reaction (LDR) to provide near real-time readout of target biomarkers. Heightened concerns on potential bioterrorism threats, such as rapid dissemination of pathogenic bacteria or viruses into …

A Preliminary Examination Of A Program That Provides Free Blood Glucose Testing Meters, And Subsidies On Test-Strips To Adult Diabetics, Cecil White

Abraham S. Fischler College of Education ETD Archive

This applied dissertation was designed to conduct a preliminary examination of the effects of the provision of free glucose testing meters, and test-strips subsidies on blood glucose control among diabetics. The study examined whether there was any impact on the frequency of testing, and whether there was a correlation between the frequency of testing and blood sugar control, as measured by HbA1c tests.

The researcher conducted a study of the program using a quasi-experimental design, and used the Glucose Monitoring Patient Questionnaire to compare the results between a test group and a control group of participants. Independent t tests were …

Structural Characterization Of A Conserved, Calcium-Dependent Periplasmic Protease From Legionella Pneumophila, Debashree Chatterjee, Chelsea D. Boyd, George A. O'Toole, Holger Sondermann

Dartmouth Scholarship

The bacterial dinucleotide second messenger c-di-GMP has emerged as a central molecule in regulating bacterial behavior, including motility and biofilm formation. Proteins for the synthesis and degradation of c-di-GMP and effectors for its signal transmission are widely used in the bacterial domain. Previous work established the GGDEF-EAL domain-containing receptor LapD as a central switch in Pseudomonas fluorescens cell adhesion. LapD senses c-di-GMP inside the cytosol and relays this signal to the outside by the differential recruitment of the periplasmic protease LapG. Here we identify the core components of an orthologous system in Legionella pneumophila. Despite only moderate sequence conservation at …

Lymphangioma Circumscriptum In The Scrotum: A Case Report, Saroona Haroon, Sheema H. Hasan

Department of Pathology and Laboratory Medicine

Introduction:
Lymphangioma circumscriptum is a rare benign skin disorder involving hamartomatous lymphatic malformation of deep dermal and subcutaneous lymphatic channels. It is a therapeutic challenge for the dermatologist when it occurs at common sites such as axilla, shoulder, groin and buttocks and a diagnostic challenge for the surgeon when it occurs at rare sites such as the scrotum. Surgical treatment is the most commonly used method to treat scrotal lymphangioma circumscriptum but there are high rates of recurrence.
Case Presentation:
We report the case of a 30-year-old Pakistani man who presented with scrotal swelling which was clinically misinterpreted as an …

Outcome Of Match Related Allogeneic Stem Cell Transplantation Procedures Performed From 2004 Till 2011, Natasha Ali, Salman Naseem Adil, Mohammad Usman Shaikh, Munira Moosajee, Nehal Masood

Department of Pathology and Laboratory Medicine

We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n=34 (35%), followed by beta-Thalassemia major in n=21 (21.6%) and chronic myeloid leukemia in n=11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival …

Consumer Health Information Technology And Public Health, Julie Gleason-Comstock

Michigan Journal of Public Health

No abstract provided.

Using Community-Based Participatory Research To Investigate The Effectiveness Of Hiv/Aids Risk Reduction Counseling In An Urban African-American Community, Alicia Streater, Julie Gleason-Comstock, Cindy B. Calhoun, Barbara Jones, Silas Norman Jr.

Michigan Journal of Public Health

Introduction: Risk reduction counseling is an important component in HIV/AIDS prevention. Community-based participatory research (CBPR) was conducted to determine if a single counseling session was as effective as a two-session intervention in reducing risk behavior. Methods: Community and academic investigators jointly developed the study design. A convenience sample of 242 persons was randomized to receive either a two session intervention with Conventional HIV Testing (CHT) or a one session intervention with HIV Rapid Testing (HRT). Participants completed a risk assessment immediately preceding the test and a risk reduction plan after the test; CHT participants received a second risk reduction session. …