Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2012

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 1621 - 1650 of 1992

Full-Text Articles in Entire DC Network

Predictors Of Carbapenem Resistant Gram-Negative Bacteria In A Consortium Of Academic Medical Center Hospitals, Mera Ababneh Jan 2012

Predictors Of Carbapenem Resistant Gram-Negative Bacteria In A Consortium Of Academic Medical Center Hospitals, Mera Ababneh

Theses and Dissertations

Background: Gram-negative resistance is a growing problem worldwide. It is generally believed that rates of resistant bacteria within a hospital are a function of antibiotic use, resistant organisms brought into the hospital, infection control efforts, and underlying severity of patient illness. The relative contribution of each to a particular resistance phenotype is unclear. P. aeruginosa is responsible for many hospital acquired infections and it may become resistant to carbapenems. In addition, newer threats to the future utility of the carbapenems are carbapenemase-producing K. pneumoniae Purpose: To determine if there is an association between the volume and composition of antibiotic use, …


The Parasite That Causes Whirling Disease, Myxobolus Cerebralis, Is Genetically Variable Within And Across Spatial Scales, Nilanjan Lodh, Billie L. Kerans, Lori Stevens Jan 2012

The Parasite That Causes Whirling Disease, Myxobolus Cerebralis, Is Genetically Variable Within And Across Spatial Scales, Nilanjan Lodh, Billie L. Kerans, Lori Stevens

Clinical Lab Sciences Faculty Research and Publications

Understanding the genetic structure of parasite populations on the natural landscape can reveal important aspects of disease ecology and epidemiology and can indicate parasite dispersal across the landscape. Myxobolus cerebralis (Myxozoa: Myxosporea), the causative agent of whirling disease in the definitive host Tubifex tubifex, is native to Eurasia and has spread to more than 25 states in the USA. The small amounts of data available to date suggest that M. cerebralis has little genetic variability. We examined the genetic variability of parasites infecting the definitive host T. tubifex in the Madison River, MT, and also from …


Essential Role Of Monocyte Chemoattractant Protein-1 In Gram-Negative Bacterial Pneumonia, Gayathriy Balamayooran Jan 2012

Essential Role Of Monocyte Chemoattractant Protein-1 In Gram-Negative Bacterial Pneumonia, Gayathriy Balamayooran

LSU Doctoral Dissertations

Acute gram-negative bacterial infections are a leading cause of mortality among the nosocomial infections. Increasing numbers of immunosuppressed individuals and growing numbers of antibiotic resistant strains make antibiotic treatment difficult. Neutrophils are the first cells recruited to the site of infection and are critical players in the host defense against gram-negative bacterial pneumonia. Therefore, identification of targets that boost neutrophil-associated host defense in the lung is essential in designing better therapies to control pulmonary infections. Production of chemokines is an important step for neutrophil recruitment. Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that is important for monocyte and T-lymphocyte influx. …


Koutango: Under Reported Arboviral Disease In West Africa, Jaime Matias De Araujo Lobo Jan 2012

Koutango: Under Reported Arboviral Disease In West Africa, Jaime Matias De Araujo Lobo

LSU Doctoral Dissertations

Arthropod-borne viruses (arboviruses) are among the most common agents of human febrile illnesses worldwide. As crucially important emerging pathogens, they have caused multiple, notable epidemics of human disease and unnoticed epizootics over recent decades. Despite the public health relevance, very little is known about the geographic distribution of the agents and vectors, relative impact, and risk factors associated to the arboviral infection in many regions of the world and in the tropics in particular. Presented in this dissertation is an experimental study that explores the serology screening of serum samples from 151 patients whom were diagnosed with undifferentiated febrile illness …


Demography And Reproductive Biology Of The Gopher Tortoise (Gopherus Polyphemus) Population At White Oak Plantation, Nassau County, Florida, Julia Rachel Smith Jan 2012

Demography And Reproductive Biology Of The Gopher Tortoise (Gopherus Polyphemus) Population At White Oak Plantation, Nassau County, Florida, Julia Rachel Smith

UNF Graduate Theses and Dissertations

The demography and reproductive biology of the gopher tortoise (Gopherus polyphemus) was studied for two years at White Oak Plantation (WOP), located in northeast Florida along the St. Mary’s river. Two sub‐populations were studied in regions I referred to as Site A and Site B. I located 312 burrows and captured 109 different tortoises, either by hand or using bucket traps. Tortoise density was 4.48/ha at Site A and only 1.15/ha at Site B. Juveniles were the most abundant age class overall, while hatchlings were numerous at Site A but virtually absent at Site B. The combined sex ratio for …


An Occupational Therapy-Based Education Program For Caregivers Of Individuals With Cerebral Palsy: A Culturally Conscious Perspective, Allison L. Kalb, Diana L. Huettl Jan 2012

An Occupational Therapy-Based Education Program For Caregivers Of Individuals With Cerebral Palsy: A Culturally Conscious Perspective, Allison L. Kalb, Diana L. Huettl

Occupational Therapy Capstones

Introduction: Individuals with cerebral palsy (CP) are able to lead functional, productive, and fulfilling lives when provided the opportunity. In the country of Ghana, the prevalence of CP is estimated to be one out of every 300 births (Purple Field Productions [PFP], 2011), however, a lack of education about CP and other disabilities, limited access to healthcare services, and scarce resources hamper the Ghanaian people’s opportunities for habilitation (Reynolds, 2010; Tinney, Chiodo, Haig, & Wiredu, 2007). In addition, cultural beliefs and societal attitudes toward people with disabilities in Ghana pose a barrier for those individuals to fully participate in occupation. …


A Hospital For Maine: Part 1- The Rise Of Maine General Hospital, Maine Medical Center Jan 2012

A Hospital For Maine: Part 1- The Rise Of Maine General Hospital, Maine Medical Center

Histories

Part One: The story of Maine Medical Center is rooted in Victorian America and owes much to the social conscience of the times. Great changes were taking place in the years preceding the construction of Maine’s first general hospital. Industrialization, European immigration, breakthroughs in medical science, new public health policies, and the Civil War formed the crucible out of which it emerged. Only 100 years before, such an institution would have been virtually unimaginable.


A Hospital For Maine: Part 8- Index, Maine Medical Center Jan 2012

A Hospital For Maine: Part 8- Index, Maine Medical Center

Histories

No abstract provided.


Beyond Nuremberg: A Critique Of Informed Consent In Third World Human Subject Research , Jacob Schuman Jan 2012

Beyond Nuremberg: A Critique Of Informed Consent In Third World Human Subject Research , Jacob Schuman

Journal of Law and Health

This Article discusses the history of informed consent, critically analyzes this principle, and suggests an alternative approach to informed consent. Part II explores the concept of informed consent, including its philosophical bases, its implementation through FDA regulations, and current proposals on how to protect the principle in drug testing conducted abroad. Part III performs a critical analysis of the principle of informed consent; first providing an empirical examination of the realities of Third World human subject research, and then questioning both the coherence of an abstract “right” to informed consent, as well as the possibility of truly autonomous “consent” to …


Bullies In A Wired World: The Impact Of Cyberspace Victimization On Adolescent Mental Health And The Need For Cyberbullying Legislation In Ohio, Kelly A. Albin Jan 2012

Bullies In A Wired World: The Impact Of Cyberspace Victimization On Adolescent Mental Health And The Need For Cyberbullying Legislation In Ohio, Kelly A. Albin

Journal of Law and Health

This Note examines cyberbullying's impact on adolescents' mental health and psychological development and explores an Ohio-specific legislative response to the problem. Part II addresses the urgent need for cyberbullying legislation, the inadequacy of Ohio law, and the detrimental effects that may result when juveniles are targeted by cyberbullies. Part III demonstrates how other states have reacted to the cyberbullying problem by amending already enacted bullying statutes or by creating new and specific cyberbullying laws. Part IV proposes a new cyberbullying statute that criminalizes the more extreme cases of cyberbullying, incorporates age as a sentencing factor, and introduces school-employee liability for …


Yellow, In Peril: How Public Health Discourse On Tuberculosis (Tb) Reveals, Refines, And Reinforces The Racial Stigmatization Of Asian Americans, Laura Dellplain Jan 2012

Yellow, In Peril: How Public Health Discourse On Tuberculosis (Tb) Reveals, Refines, And Reinforces The Racial Stigmatization Of Asian Americans, Laura Dellplain

Honors Papers

In this paper, I argue that while public health discourse on tuberculosis may reveal existent epidemiological trends in and among particular social groups, the discursive framing of this data unnecessarily racializes the disease. More specifically, public health discourse uses frameworks of "othering" and an imagined transnationalism to reflect but also refine and reinforce historicized stigmas of Asian Americans as non-normative, perpetual outsiders, and disease carriers. I assert that this discursive raciliazation of TB superficially constructs a causal link between Asian Americans and the incidence of TB in America and consequently results in significant social and political costs for many Asian …


Computational Investigation Of The Mechanism Of N5-Carboxyaminoimidazole Ribonculeotide Synthetase, Venkata Pakkala Jan 2012

Computational Investigation Of The Mechanism Of N5-Carboxyaminoimidazole Ribonculeotide Synthetase, Venkata Pakkala

Electronic Theses and Dissertations

N5-CAIR synthetase catalyzes the conversion of 5-amino-imidazole ribonucleotide (AIR), Mg2ATP, and bicarbonate into N5-CAIR, Mg2ADP, and inorganic phosphate. DFT and ONIOM QM/MM computations revealed that the first step in the reaction mechanism of N5-CAIR synthetase involves the formation of dianionic carboxyphosphate (CP) from the attack of bicarbonate on the γ- phosphate of Mg2ATP, through an SN2 type transition structure. Properties of CP were never reported, as this compound is extremely unstable (t1/2 of 70 ms). Therefore, high level ab inito (MP2 and CCSD(T)), and DFT (B3LYP, BB1K, M05-2X, M06-2X and MPW1K) methods were used to investigate the structure and energetics …


A Hospital For Maine: Part 5- A New Millennium, Maine Medical Center Jan 2012

A Hospital For Maine: Part 5- A New Millennium, Maine Medical Center

Histories

Part Five: The turn of a new century at Maine Medical Center.


Retrospective Epidemiologic Analysis Of Influenza Pandemics In Arkansas, A, A. J. Gray, D. Nguyen, B. M. Rowley Jan 2012

Retrospective Epidemiologic Analysis Of Influenza Pandemics In Arkansas, A, A. J. Gray, D. Nguyen, B. M. Rowley

Journal of the Arkansas Academy of Science

This study compares influenza mortality in Arkansas during the pandemics of: 1918 (aka Spanish flu), 1957, 1968, and 2009 (H1N1, aka Swine flu). Death certificate and U.S. census data were gathered and analyzed for statistical differences in mortalities based on sex, age, and geographic regions of Arkansas for each pandemic. The geographic regions were defined by the five Public Health Units classified by the Arkansas Department of Health. Regional mortalities were also analyzed across all pandemics to investigate how the different pandemics affected each individual region. Chi-square analyses for each pandemic showed only the 1918 pandemic had statistical differences between …


Molecular Characterization Of Multidrug Resistant Pseudomonas Aeruginosa / Abdelkodose Mohammed Hussen Abdulla, Abdelkodose Mohammed Hussen Abdulla Jan 2012

Molecular Characterization Of Multidrug Resistant Pseudomonas Aeruginosa / Abdelkodose Mohammed Hussen Abdulla, Abdelkodose Mohammed Hussen Abdulla

Student Works (2010-2019)

Pseudomonas aeruginosa is one of the main causes of healthcare-associated infections among hospitalized patients. Healthcare-associated infections predominantly lead to pneumonia, urinary tract infections, as well as skin and soft-tissue infections. This organism is commonly multiresistant and leads to morbidity and mortality. In this study, the resistance mechanisms of 88 clinical P. aeruginosa isolates from the Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia were evaluated. The antibiotics resistance profiles of these isolates were determined and this was followed by evaluating the expression levels of AmpC cephalosporinase, the multidrug efflux pumps, the OprD outer membrane porin …


Detection Of Teeth Surface Defects Using Fiber Optic Displacement Sensor / Adi Izhar Che Ani, Che Ani Adi Izhar Jan 2012

Detection Of Teeth Surface Defects Using Fiber Optic Displacement Sensor / Adi Izhar Che Ani, Che Ani Adi Izhar

Student Works (2010-2019)

Fiber optic displacement sensor has been used recently for general medical diagnostics and in industry for the characterization and detection of defects in engineering components. However the lack of understanding of parameter performance of such a sensor in teeth has largely precluded its application to dentistry. This research describes sensor system adopting an intensity modulation technique that used a concentric type bundled optical fiber as a probe in conjunction with the real teeth, artificial teeth, hybrid composite resin teeth and mirror as the reflecting targets. The performance of the sensor is investigated on the linear range, sensitivity and the peak …


Antimicrobial Activity Of Mesophilic And Psychrotrophic Microfungi Isolate From: King George Island And Greenwich Island, Maritime Antarctica / Wessam Mansour Filfilan, Wessam Mansour Filfilan Jan 2012

Antimicrobial Activity Of Mesophilic And Psychrotrophic Microfungi Isolate From: King George Island And Greenwich Island, Maritime Antarctica / Wessam Mansour Filfilan, Wessam Mansour Filfilan

Student Works (2010-2019)

This research was made to study the antimicrobial activity of fungal isolates from different regions of maritime, Antarctica, namely, King George Island and Greenwich Island (Barrientos Island, Dee Island and Ambato point). A total of 17 isolates composed of 7 mesophilic and 10 psychrotrophic fungi were tested in-vitro against Gram-positive, Gram-negative bacteria and yeast human pathogens. Initial antimicrobial activity screening of Antarctic isolates was made using plug assay method. Five test-microorganisms namely Candida albicans, Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa were used. Only five (out of 17) fungal isolates showed inhibition potency against the test-microorganisms and majority …


16s Rrna Pcr-Dgge Based Bacterial Community Structure In Activated Sludge Systems / Ang Pey Pey, Pey Pey Ang Jan 2012

16s Rrna Pcr-Dgge Based Bacterial Community Structure In Activated Sludge Systems / Ang Pey Pey, Pey Pey Ang

Student Works (2010-2019)

We studied bacterial community structure in three different sewage treatment plants (STPs), namely STP 1, 2 and 3, in Klang Valley. STP 1, 2 and 3 were located in residential, commercial and light-industrial areas, respectively. Cu and Pb pollution detected in STP 3 was shown to affect its sludge production and biomass. Investigation by 16S rRNA PCR-DGGE demonstrated that bacterial community structures in the three STPs were different; and heavy metal resistant bacteria were predominant at STP 3. In order to determine the effects of heavy metal pollution on bacterial community structures, we used the canonical correspondence analysis, and showed …


Studies On Antioxidant And Cytotoxic Activities Of Dichloromethane Extract Of Marasmius Species / Teesilia Mohamed Nor, Teesilia Mohamed Nor Jan 2012

Studies On Antioxidant And Cytotoxic Activities Of Dichloromethane Extract Of Marasmius Species / Teesilia Mohamed Nor, Teesilia Mohamed Nor

Student Works (2010-2019)

Although much research has been focused on the therapeutic and medicinal effects of wild mushrooms, there is still paucity of information on the pharmacological properties of Marasmius species. The present study was undertaken to evaluate the cytotoxic and antioxidant activities of M. guyanensis (KUM 20044, KUM 20222, and KUM 20117), M. kanchingnensis (KUM 20160), Marasmius sp. (KUM 20067), M. ruforotula (KUM 20111, KUM 20112) and M. selangorensis (KUM 20181). Crude dichloromethane extracts were prepared from the mycelial biomass grown in liquid Glucose-Yeast-Malt- Peptone (GYMP) using a soxhlet extractor system. The cytotoxic effect of the Marasmius extracts was screened using Neutral …


Micropropagation, Antioxidant And Antimicrobial Activities Of Asparagus Officinalis Cv. Mary Washington In Vivo And In Vitro / Arash Khorasani Esmaeili, Arash Khorasani Esmaeili Jan 2012

Micropropagation, Antioxidant And Antimicrobial Activities Of Asparagus Officinalis Cv. Mary Washington In Vivo And In Vitro / Arash Khorasani Esmaeili, Arash Khorasani Esmaeili

Student Works (2010-2019)

In recent years there has been renewed interest in natural medicines that are obtained from plant parts or plant extracts. Asparagus officinalis is a herbaceous perennial plant that belongs to Liliaceae family, a valued vegetable for its medicinal properties. The present study was carried out in order to establish an efficient in vitro propagation protocol for Asparagus officinalis. For this purpose, the nodal explants of Asparagus officinalis Cv. Mary Washington were cultured on MS medium containing 3% sucrose and different concentrations of NAA and BAP or IBA and Kn, mixed or separately with range of 0-1.5 mg/l for BAP/Kn and …


Antioxidant And Antimicrobial Activities Of Sonneratia Albain Vitro And In Vivo : Comparative Study With Rhizophora Mucronata And Bruguiera Gymnorrhiza / Md. Imdadul Haq, Haq Md. Imdadul Jan 2012

Antioxidant And Antimicrobial Activities Of Sonneratia Albain Vitro And In Vivo : Comparative Study With Rhizophora Mucronata And Bruguiera Gymnorrhiza / Md. Imdadul Haq, Haq Md. Imdadul

Student Works (2010-2019)

The present study evaluated the antioxidant and antimicrobial potential of three mangrove species namely, Sonneratial alba, Rhizophora mucronat and Bruguiera gymnorrhiza. The bioactivities of methanol, ethanol and chloroform extracts of in vivo and in vitro explants of S. alba and in vivo explants of R. mucronata and B. gymnorrhiza were evaluated. The effects of growth regulators on seed germination of S. alba, to obtain the in vitro explants, were also studied. In the first part of bioactivity study, total phenolic contents were detected by using the Folin-ciocalteu assay. Ethanol extract of leaves of R. mucronata had the highest result for …


Effects Of Brucea Javanica And Piper Betle Extracts On Oral Candida Spp / Mohd-Al-Faisal Nordin, Nordin Mohd Al-Faisal Jan 2012

Effects Of Brucea Javanica And Piper Betle Extracts On Oral Candida Spp / Mohd-Al-Faisal Nordin, Nordin Mohd Al-Faisal

Student Works (2010-2019)

Candida species is an opportunistic microorganism residing in the human oral cavity. There is increasing prevalence of candidal infections in the oral cavity largely because of the increasing size of the population at risk. The rise in diagnosed cases of oral candidiasis is also due to the immunosuppressive effect of prescribed antifungal agents on resistant hosts. The ability of Candida species to adhere on mucosal tissues and/or denture surfaces, and the production of hydrolytic enzymes along with defective host immunity are among the known key factors of invasions and pathogenesis of oral candida. Although Candida albicans remains as the most …


Microbial Assessment Of Dental Unit Waterline System (Duws)/ Chua Chong Sing, Chong Sing Chua Jan 2012

Microbial Assessment Of Dental Unit Waterline System (Duws)/ Chua Chong Sing, Chong Sing Chua

Student Works (2010-2019)

Introduction: Dental Unit Waterline System (DUWS) is an interconnected water network found inside a dental chair unit (DCU) that allows water to pass through and deliver to the patient’s mouth during treatment. Many previous studies demonstrated the DUWS water was often heavily contaminated and might pose a risk of infection to the patients as well as dental personnel. Objective: To determine the sanitary level of output water from DCUs and assess the effectiveness of silver-coated tubing used in DCU in reducing microbial counts in DUWS water. Methods: Water from sources which include the air-water syringe, low speed handpiece, high speed …


Early Childhood Caries, Dietary Habits And Nutritional Status Of Toddlers : An Intervention Study In Kelantan / Ruhaya Hasan, Ruhaya Hasan Jan 2012

Early Childhood Caries, Dietary Habits And Nutritional Status Of Toddlers : An Intervention Study In Kelantan / Ruhaya Hasan, Ruhaya Hasan

Student Works (2010-2019)

The aim of this study was to assess the effectiveness of a health promotion intervention program (TIPTOP package) in preventing early childhood caries (ECC), to improve nutritional status and dietary habits among toddlers. The study design was an intervention prospective study and conducted in Tumpat and Pasir Mas districts in Kelantan. The intervention group was 2-3 year old toddlers in Tumpat and received the TIPTOP package, while the control group was in Pasir Mas and received the normal toddlers’ oral health program under the MOH. Baseline information on a proxy population of 527 preschool children (5-6 years old) showed that …


The Development Of Single-Chain Variable Fragment (Scfv) Antibodies Against Toxoplasma Gondii By Phage-Display / Sherene Lim Swee Yin, Sherene Swee Yin Lim Jan 2012

The Development Of Single-Chain Variable Fragment (Scfv) Antibodies Against Toxoplasma Gondii By Phage-Display / Sherene Lim Swee Yin, Sherene Swee Yin Lim

Student Works (2010-2019)

The obligate intracellular protozoan parasite, Toxoplasma gondii, is the etiologic agent of an opportunistic infection affecting mainly immunocompromised patients, infants and neonates with immature immune system. There is a need for alternative antiparasitic treatment for toxoplasmosis due to the associated toxicity and teratogenicity of the current drug treatment regime. To investigate a potential alternative strategy, we have used the phage-display system and developed a novel biopanning procedure to isolate single-chain Fv (scFv) antibodies probed against tachyzoites – the rapidly replicating form of T. gondii responsible for acute disease. The resulting scFv antibody library (complexity of 1.62 X 104 independent transformants) …


Genetic And Phenotypic Characterisation Of Clinical Methicillin-Resistant Staphylococcus Aureus In A Malaysian Hospital / Lim King Ting, King Ting Lim Jan 2012

Genetic And Phenotypic Characterisation Of Clinical Methicillin-Resistant Staphylococcus Aureus In A Malaysian Hospital / Lim King Ting, King Ting Lim

Student Works (2010-2019)

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the main bacterial pathogens responsible for a variety of nosocomial infections ranging from soft-tissue infections to bacteremia. Since most MRSA is often resistant to multiple antibiotics, this has raised a concern over the limited choice of antimicrobial-agents for treatment of life-threatening cases. The objectives of this study were to determine the antimicrobial resistance profiles, presence of resistance and virulence genes, to investigate the molecular epidemiology of MRSA and their evolution over a six-year period. The antibiograms of 188 MRSA strains isolated from UMMC were analyzed by disk-diffusion test and minimum inhibitory concentrations. The …


Identification Of Bcl-Xl Induced Micrornas Involved In The Apoptotic Properties Of Human Lung Adenocarcinoma Cells, A549 / Norahayu Othman, Norahayu Othman Jan 2012

Identification Of Bcl-Xl Induced Micrornas Involved In The Apoptotic Properties Of Human Lung Adenocarcinoma Cells, A549 / Norahayu Othman, Norahayu Othman

Student Works (2010-2019)

Bcl-xL is an anti-apoptotic protein that is frequently found to be overexpressed in lung adenocarcinoma leading to an inhibition of apoptosis and associated with poor prognosis of this disease. Recently, the roles of microRNAs (miRNAs) in regulating apoptosis and cell survival during tumorigenesis have become evident, with cancer cells showing perturbed expression of various miRNAs. In this project, we utilized miRNA microarrays to determine if miRNA dysregulation in bcl-xL silenced A549 lung adenocarcinoma cells could be involved in apoptotic behavior. Data from qRT-PCR and Western blotting indicated that a siRNA-based transfection induced a decrease of bcl-xL expression in A549 cells …


Antimicrobial Activity Of Mesophilic And Psychrotropic Microfungi Isolates From: King George Island And Greenwich Island, Maritime Antarctica / Wessam Mansour Filfilan, Mansour Filfilan Wessam Jan 2012

Antimicrobial Activity Of Mesophilic And Psychrotropic Microfungi Isolates From: King George Island And Greenwich Island, Maritime Antarctica / Wessam Mansour Filfilan, Mansour Filfilan Wessam

Student Works (2010-2019)

This research was made to study the antimicrobial activity of fungal isolates from different regions of maritime, Antarctica, namely, King George Island and Greenwich Island (Barrientos Island, Dee Island and Ambato point). A total of 17 isolates composed of 7 mesophilic and 10 psychrotrophic fungi were tested in-vitro against Gram-positive, Gram-negative bacteria and yeast human pathogens. Initial antimicrobial activity screening of Antarctic isolates was made using plug assay method. Five test-microorganisms namely Candida albicans, Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa were used. Only five (out of 17) fungal isolates showed inhibition potency against the test-microorganisms and majority …


Quorum Sensing And Quorum Quenching Studies In Clinical Acinetobacter Isolates From Ummc / Deepa Anbazhagan, Deepa Anbazhagan Jan 2012

Quorum Sensing And Quorum Quenching Studies In Clinical Acinetobacter Isolates From Ummc / Deepa Anbazhagan, Deepa Anbazhagan

Student Works (2010-2019)

Quorum sensing is a term that describes an environmental sensing system that allows bacteria to monitor their own population density. Many gram negative bacteria use N-acyl-homoserine lactones (AHLs) as autoinducing quorum sensing signal molecules. This cell-density dependent regulation of gene expression contributes significantly to the size and development of the biofilm. Acinetobacter spp. are now emerging as important nosocomoial pathogens and it has been shown that they form biofilms with enhanced antibiotic resistance. In this study, we sought to find out if the biofilm formation among clinical isolates of Acinetobacter spp. is under the control of autoinducing quorum sensing molecules. …


Adherence To Highly Active Anti-Retroviral Treatment (Haart) And Its Associated Factors Among Hiv-Positive Patients In Sungai Buloh Hospital, Malaysia / Umar Yagoub Mohammed Yousif, Umar Yagoub Mohammed Yousif Jan 2012

Adherence To Highly Active Anti-Retroviral Treatment (Haart) And Its Associated Factors Among Hiv-Positive Patients In Sungai Buloh Hospital, Malaysia / Umar Yagoub Mohammed Yousif, Umar Yagoub Mohammed Yousif

Student Works (2010-2019)

HIV/AIDS is one of the most destructive health diseases of modern times, affecting approximately 45.5 million people worldwide. But the advent of the Highly Active Antiretroviral Therapy (HAART) in 1996 has significantly reduced HIV/AIDS-related mortality and morbidity and it has allowed many previously bed-ridden patients to live healthier and more productive lives. In order for the treatments to be successful, a very high level of adherence to HAART is required. It is estimated that at least 95% adherence to antiretroviral treatment is essential to reduce the replication of the virus and prevent the development of resistance to treatment. Generally, adherence …