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2012

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Articles 1471 - 1500 of 1992

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Never Say Never: "Never Events" In Medicare, John Crist Jan 2012

Never Say Never: "Never Events" In Medicare, John Crist

Health Matrix: The Journal of Law-Medicine

No abstract provided.

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Understanding Viral Transmission Behavior Via Protein Intrinsic Disorder Prediction: Coronaviruses, Gerard Kian-Meng Goh, A. Keith Dunker, Vladimir N. Uversky Jan 2012

Understanding Viral Transmission Behavior Via Protein Intrinsic Disorder Prediction: Coronaviruses, Gerard Kian-Meng Goh, A. Keith Dunker, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Besides being a common threat to farm animals and poultry, coronavirus (CoV) was responsible for the human severe acute respiratory syndrome (SARS) epidemic in 2002–4. However, many aspects of CoV behavior, including modes of its transmission, are yet to be fully understood. We show that the amount and the peculiarities of distribution of the protein intrinsic disorder in the viral shell can be used for the efficient analysis of the behavior and transmission modes of CoV. The proposed model allows categorization of the various CoVs by the peculiarities of disorder distribution in their membrane (M) and nucleocapsid (N). This categorization …

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Professional Product Review Vol. 7 No. 3, American Dental Association, Council On Scientific Affairs Jan 2012

Professional Product Review Vol. 7 No. 3, American Dental Association, Council On Scientific Affairs

Professional Product Review

A user-friendly newsletter from the ADA Council on Scientific Affairs offering scientifically sound, unbiased, and clinically relevant information to member dentists about professional dental products tested by the ADA. This collection is historical and may not reflect current standards. For up-to-date information contact the ADA.

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Modulation Of Anti-Tumor Immune Response By Tgf-Β-Inducible Early Gene 1 (Tieg1), Andi Cani Jan 2012

Modulation Of Anti-Tumor Immune Response By Tgf-Β-Inducible Early Gene 1 (Tieg1), Andi Cani

Wayne State University Theses

Cancer immunotherapy has had limited clinical efficacy partly because regulatory T cells (Treg) suppress the immune response to tumor-associated antigens. Inducible regulatory T cells (iTreg), which are converted from naïve CD4 T cells by TGF-β, an abundant cytokine in the tumor microenvironment, may contribute to this immune suppression. Induction of Foxp3 by TGF-β is mediated by the transcription factor TIEG1 and abrogation of this protein prevents Foxp3 expression. We are testing the hypothesis that blockade of TIEG1 to prevent iTreg conversion will enhance immune response in DNA vaccination to the tumor associated antigen Her-2. Wild type and TIEG1 knockout mice …

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Ada News Convention Daily - 2012 Day 4, American Dental Association, Publishing Division Jan 2012

Ada News Convention Daily - 2012 Day 4, American Dental Association, Publishing Division

ADA News

The ADA News Daily (also called the ADA News Convention Daily) is a special edition of the ADA News published each day during American Dental Association Annual Sessions.

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Study Guide For United In Anger: A History Of Act Up, Matt Brim Jan 2012

Study Guide For United In Anger: A History Of Act Up, Matt Brim

Open Educational Resources

The United in Anger Study Guide facilitates classroom and activist engagement with Jim Hubbard’s 2012 documentary, United in Anger: A History of ACT UP. The Study Guide contains discussion sections, projects and exercises, and resources for further research about the activism of the New York chapter of ACT UP (AIDS Coalition to Unleash Power). The Study Guide is a free, interactive, multimedia resource for understanding the legacy of ACT UP, the film’s role in preserving that legacy, and its meaning for viewers' lives.

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Antibody Production During Ehrlichial Infection : Development And Specificity Of T Cell-Independent Igm, Derek Daniel Jones Jan 2012

Antibody Production During Ehrlichial Infection : Development And Specificity Of T Cell-Independent Igm, Derek Daniel Jones

Legacy Theses & Dissertations (2009 - 2024)

Historically, the role for antibodies in mediating protective immunity against intracellular pathogens was thought to be minimal. However, our previous studies demonstrated that antibodies were both necessary and sufficient to establish protective immunity against Ehrlichia muris, a tick-transmitted intracellular bacterium. The identification of a unique population of CD11c-expressing IgM-secreting plasmablasts in the spleen during early infection of mice led to the appreciation that IgM was a critical component of the humoral immune response, and that IgM was required for control of acute ehrlichial infection. Here, we addressed the generation of the IgM-secreting cells, as well as the properties of the …

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Prognostic Implications Of Oral Health Status In Hiv-Positive Women In St. Petersburg, Russia, Anna Vinogradova Jan 2012

Prognostic Implications Of Oral Health Status In Hiv-Positive Women In St. Petersburg, Russia, Anna Vinogradova

Legacy Theses & Dissertations (2009 - 2024)

Objective: To assess state of oral health in HIV-positive women in St. Petersburg, Russia and to study the association of oral health with pregnancy status and other factors in this sample.

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The Burden Of Hepatitis C Virus In New York State, Rachel Hart Malloy Jan 2012

The Burden Of Hepatitis C Virus In New York State, Rachel Hart Malloy

Legacy Theses & Dissertations (2009 - 2024)

Hepatitis C virus (HCV) infection is estimated to be the most common chronic blood-borne infection in the United States (US). Annual incidence of HCV in the US peaked in the late 1980's, declined steadily through the 1990's and has plateaued since 2003 with approximately 18,000 new cases in 2008. The morbidity and mortality associated with HCV is expected to rise until at least 2015. Due to the high rate of asymptomatic cases, inherent limitations with target screening recommendations, limitations with screening technologies and scarce resources for surveillance nationwide, quantification of the burden is difficult. US estimates of disease burden have …

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Influenza In The 21st Century : Assessment Of The 2009 H1n1 Pandemic Severity, Enhanced Surveillance Methods, And Pediatric Influenza-Associated Deaths, Dina M. Hoefer Jan 2012

Influenza In The 21st Century : Assessment Of The 2009 H1n1 Pandemic Severity, Enhanced Surveillance Methods, And Pediatric Influenza-Associated Deaths, Dina M. Hoefer

Legacy Theses & Dissertations (2009 - 2024)

Influenza is among the most important of the endemic, epidemic, and pandemic diseases infecting humans. In June 2009, the World Health Organization raised the worldwide pandemic alert level to Phase 6 in response to the ongoing global spread of 2009 pandemic influenza A (H1N1) virus (pH1N1).1 The 2009 H1N1 influenza pandemic presented a unique opportunity and provided resources to monitor and study influenza in a way that would and could not be supported during a `typical' influenza season. Research objectives included: 1) characterizing the severity of illness among hospitalized patients infected with pH1N1; 2) assessing the utility of hospital discharge …

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Identification Of Epitopes On Ricin Toxin's Enzymatic Subunit (Rta) Critical For Eliciting Neutralizing Antibodies And Protective Immunity, Joanne Marie O'Hara Jan 2012

Identification Of Epitopes On Ricin Toxin's Enzymatic Subunit (Rta) Critical For Eliciting Neutralizing Antibodies And Protective Immunity, Joanne Marie O'Hara

Legacy Theses & Dissertations (2009 - 2024)

Ricin toxin's enzymatic subunit (RTA) is a 267 amino acid RNA N-glycosidase that selectively depurinates eukaryotic ribosomal RNA and arrests protein synthesis. The crystal structure of RTA revealed that the protein assumes three distinct folding domains (FD). Residues within FD1 and FD2 form RTA's active site pocket and are proposed to interface with ribosomal proteins, while FD3's primary function is to associate with ricin's B subunit (RTB). In this study I sought to identify the regions of RTA that are important in eliciting toxin-neutralizing antibodies (TNA), as this information is critical for current efforts to develop RTA-based subunit vaccines. I …

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Body Size And Mortality In Post-Medieval England, Gail Margaret Hughes-Morey Jan 2012

Body Size And Mortality In Post-Medieval England, Gail Margaret Hughes-Morey

Legacy Theses & Dissertations (2009 - 2024)

Short stature and body mass at both extremes of the distribution have consistently been linked to poor health outcomes in modern populations, but the nature of the relationship between body size and mortality is poorly understood. This dissertation examines the relationship between stature, body mass, and mortality, and how that relationship may have varied with socioeconomic status and evidence of morbidity in post-medieval England. Adults from Chelsea Old Church, an 18th-19th century high status skeletal collection from the outskirts of London, and Lower Saint Bride's, an 18th-19th century low status skeletal collection from central London, both housed at the Museum …

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Detection And Epidemiological Patterns Of Drug Resistance Mutations In Nys Plasmodium Falciparum Clinical Malaria Specimens, Jennifer L. Conaway Jan 2012

Detection And Epidemiological Patterns Of Drug Resistance Mutations In Nys Plasmodium Falciparum Clinical Malaria Specimens, Jennifer L. Conaway

Legacy Theses & Dissertations (2009 - 2024)

Plasmodium falciparum is a human-infective parasite that causes the most severe form of malaria. Resistance to a wide spectrum of antimalarials has been documented in this species, and single strains may be resistant to several drugs. A new technology, pyrosequencing, has been shown to be useful for the rapid detection of SNPs involved in drug resistance. It can be used in a clinical setting and readily detects new mutants, which frequently appear in this species due to strong selection for antimalarial resistance. In this study, a pyrosequencing protocol was developed to identify mutations in the Plasmodium falciparum genes Pfcrt, Pfdhps, …

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Occupational Exposure And Risk Of Skin Cancer In A Multinational European Study, Simona Surdu Jan 2012

Occupational Exposure And Risk Of Skin Cancer In A Multinational European Study, Simona Surdu

Legacy Theses & Dissertations (2009 - 2024)

Non-melanoma skin cancers (NMSC) comprise more than one third of all cancers, and are increasing worldwide. The most common NMSC are Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC). Studies on humans and animals suggest that sunlight and arsenic play important roles in the pathogenesis of these skin malignancies. However, the number of epidemiological studies focusing on NMSC in workers exposed to ultraviolet (UV) radiation or airborne arsenic is limited, and the findings are contradictory.

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Health Behind And Beyond Bars : Understanding The Link Between Incarceration And Health, Lauren C. Porter Jan 2012

Health Behind And Beyond Bars : Understanding The Link Between Incarceration And Health, Lauren C. Porter

Legacy Theses & Dissertations (2009 - 2024)

The primary aim of this dissertation is to better understand the link between incarceration and health. Drawing on a sample of young adults from the National Longitudinal Study of Adolescent Health (Add Health), the effect of incarceration on self-rated health, serious injury, STD infection, cold/flu symptoms, and blood pressure is assessed. The effect of incarceration on health behavior is also examined, including diet, smoking, binge drinking, and physical activity. In order to rule out selection bias, current and former inmates are compared to respondents who have been arrested (or arrested and convicted of a crime), but not incarcerated. Findings suggest …

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Intra And Interhost Dynamics Shaping Arbovirus Adaptation And Evolution, Alexander T. Ciota Jan 2012

Intra And Interhost Dynamics Shaping Arbovirus Adaptation And Evolution, Alexander T. Ciota

Legacy Theses & Dissertations (2009 - 2024)

Arthropod-borne viruses (arboviruses), which are predominately mosquito-borne and almost exclusively RNA viruses, are maintained in nature in complex transmission cycles involving blood sucking invertebrates and vertebrate hosts. Although over 120 arboviruses are human pathogens responsible for causing a significant and expanding global health burden, a detailed understanding of the complex interactions between these pathogens and their hosts, particularly invertebrate hosts, is lacking. Defining these interactions is necessary if we are to understand the selective pressures and, therefore, evolutionary, adaptive, and epidemiological potential of arboviruses. This requires experimental infection and evolution studies, particularly in vivo, with natural hosts. The results presented …

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Good Intentions, Bad Consequences: How Congress’S Efforts To Eradicate Hiv/Aids Stifle The Speech Of Humanitarian Organizations, Garima Malhotra Jan 2012

Good Intentions, Bad Consequences: How Congress’S Efforts To Eradicate Hiv/Aids Stifle The Speech Of Humanitarian Organizations, Garima Malhotra

Catholic University Law Review

No abstract provided.

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Identification Of 23 Specific Nucleotide Patterns In The Hn Gene Of Newcastle Disease Viruses Isolated From Iran, Majid Esmaelizad, Mehdi P. Ashtiani, Saber Jelokhani Niaraki, Khadije Hashemnejad Jan 2012

Identification Of 23 Specific Nucleotide Patterns In The Hn Gene Of Newcastle Disease Viruses Isolated From Iran, Majid Esmaelizad, Mehdi P. Ashtiani, Saber Jelokhani Niaraki, Khadije Hashemnejad

Turkish Journal of Biology

Newcastle disease is considered the most contagious poultry disease and may cause severe economic loss in the poultry industry. The present study was undertaken to focus on molecular and phylogenetic analyses of the hemagglutinin-neuraminidase (HN) gene in the Iranian isolates. The nucleotide sequence of the HN (780-903 nt) coding region of 6 Newcastle disease viruses (NDVs), isolated from various outbreaks in Iran, was determined and aligned with previously published sequences of 26 NDV isolates in GenBank; the resulting alignment was then analyzed in terms of genetic variation. The number of nucleotide sequence variations presented by each of the isolates indicated …

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Antimicrobial And Antiviral Effects Of Essential Oils From Selected Umbelliferae And Labiatae Plants And Individual Essential Oil Components, İlkay Erdoğan Orhan, Berri̇n Özçeli̇k, Murat Kartal, Yüksel Kan Jan 2012

Antimicrobial And Antiviral Effects Of Essential Oils From Selected Umbelliferae And Labiatae Plants And Individual Essential Oil Components, İlkay Erdoğan Orhan, Berri̇n Özçeli̇k, Murat Kartal, Yüksel Kan

Turkish Journal of Biology

The essential oils obtained from Anethum graveolens, Foeniculum vulgare collected at fully-mature and flowering stages, Mentha piperita, Mentha spicata, Lavandula officinalis, Ocimum basilicum (green- and purple-leaf varieties), Origanum onites, O. vulgare, O. munitiflorum, O. majorana, Rosmarinus officinalis, Salvia officinalis, and Satureja cuneifolia, as well as the widely encountered components in essential oils (\gamma-terpinene, 4-allylanisole, (-)-carvone, dihydrocarvone, D-limonene, (-)-phencone, cuminyl alcohol, cuminyl aldehyde, cuminol, trans-anethole, camphene, isoborneol, (-)-borneol, L-bornyl acetate, 2-decanol, 2-heptanol, methylheptane, farnesol, nerol, isopulegol, citral, citronellal, citronellol, geraniol, geranyl ester, linalool, linalyl oxide, linalyl ester, \alpha-pinene, \beta-pinene, piperitone, (-)-menthol, isomenthone, carvacrol, thymol, vanillin, and eugenol), were screened for their …

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Evaluation Of Antiinflammatory And Antinociceptive Effects Of Some Juniperus Species Growing In Turkey, Ni̇lüfer Orhan, Esra Akkol, Fatma Ergun Jan 2012

Evaluation Of Antiinflammatory And Antinociceptive Effects Of Some Juniperus Species Growing In Turkey, Ni̇lüfer Orhan, Esra Akkol, Fatma Ergun

Turkish Journal of Biology

Different parts and products of Juniperus species have been used as folk medicine for various infectious diseases, rheumatism, and wounds in Turkey. In order to evaluate this traditional usage, antiinflammatory and antinociceptive activities of leaf and berry extracts of 3 Juniperus species (J. excelsa, J. foetidissima, and J. sabina) were investigated. Additionally, antiinflammatory and antinociceptive activities of subextracts of J. oxycedrus subsp. oxycedrus (Joso) berries and leaves were evaluated. The p-benzoquinone-induced writhing test for antinociceptive activity and the carrageenan-induced hind paw edema model for antiinflammatory activity in mice were employed. Ethanol extract prepared from berries of J. foetidissima provided a …

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Evaluation Of Nested Pcr Method For Diagnosis Of Meningitis Due To Neisseria Meningitidis And Haemophilus Influenzae, Zahra Hojjati Bonab, Safar Farajnia, Reza Ghotaslou, Elhameh Nikkhah Jan 2012

Evaluation Of Nested Pcr Method For Diagnosis Of Meningitis Due To Neisseria Meningitidis And Haemophilus Influenzae, Zahra Hojjati Bonab, Safar Farajnia, Reza Ghotaslou, Elhameh Nikkhah

Turkish Journal of Biology

Meningitis due to Neisseria meningitidis and Haemophilus influenzae is a common infectious disease among infants and children that can be fatal in the absence of rapid and proper diagnosis and treatment. Therefore, a rapid and sensitive method for diagnosis is a high priority. The aim of this study was to compare the performance of culture, conventional polymerase chain reaction (PCR), and nested PCR methods for diagnosis of meningitis caused by N. meningitidis and H. influenzae. A total of 106 cerebrospinal fluid samples were collected from infants and children suspected of having meningitis. A portion of these samples were used for …

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Cutaneous Anthrax Patients In Eastern Anatolia, Turkey: A Review Of 44 Adults Cases, Kemaletti̇n Özden, Zülal Özkurt, Serpi̇l Erol, Muhammet Hami̇dullah Uyanik, Mehmet Parlak Jan 2012

Cutaneous Anthrax Patients In Eastern Anatolia, Turkey: A Review Of 44 Adults Cases, Kemaletti̇n Özden, Zülal Özkurt, Serpi̇l Erol, Muhammet Hami̇dullah Uyanik, Mehmet Parlak

Turkish Journal of Medical Sciences

Anthrax is a zoonotic infectious disease caused by B. anthracis. It remains as an important issue in developing countries and it is a potential threat for the world because of its use as a biological weapon. In this study, we evaluated the epidemiological, clinical, and laboratory characteristics of 44 patients with cutaneous anthrax in our region. Materials and methods: The study included 44 cutaneous anthrax patients admitted to our hospital from the Eastern Anatolia Region of Turkey between 2005 and 2008. Results: Out of 44 cases, 24 (54.5%) were male and 20 (45.5%) female. The mean age was 41 ± …

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Seroprevalence Of Major Blood-Borne Infections Among Blood Donors In Kano, Nigeria, Emmanuel Nwankwo, Imoru Momodu, Ismaila Umar, Babashani Musa, Solomon Adeleke Jan 2012

Seroprevalence Of Major Blood-Borne Infections Among Blood Donors In Kano, Nigeria, Emmanuel Nwankwo, Imoru Momodu, Ismaila Umar, Babashani Musa, Solomon Adeleke

Turkish Journal of Medical Sciences

To examine the seroprevalence of common blood infections among blood donors, which remains a major concern in transfusion medicine in Nigeria. Blood transfusion is one of the known therapeutic interventions that cut across a number of clinical disciplines. Materials and methods: The seroprevalences of human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B surface antigen (HBsAg), and syphilis among 280 blood donors at the Murtala Mohammed Specialist Hospital (MMSH) were determined. The seroprevalences of the pathogens were determined with regard to age, sex, donor category, and occurrence of association pathogens. Between June and December 2008, 276 males (98.6%) and …

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Plasma Lipid Levels In Patients With Acute Bacterial Infections, Mohammad Nassaji, Raheb Ghorbani Jan 2012

Plasma Lipid Levels In Patients With Acute Bacterial Infections, Mohammad Nassaji, Raheb Ghorbani

Turkish Journal of Medical Sciences

To assess the impact of acute bacterial infections on plasma lipid levels and to determine the value of plasma lipid measurements in the diagnosis of acute bacterial infection. Materials and methods: A cross-sectional study was conducted involving 112 patients with acute bacterial infections admitted in hospital and 112 healthy individuals as controls. Levels of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein, and triglycerides were measured in blood samples of all subjects. Mean levels of serum lipids were compared in both groups. Results: Both groups were matched based on age (P = 0.10), sex (P = 0.789), BMI (P = 0.515), …

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A Retrospective Study Of Borrelia Burgdorferi Antibodies In Dogs In Minnesota, Aneela Durrani, Sagar Goyal Jan 2012

A Retrospective Study Of Borrelia Burgdorferi Antibodies In Dogs In Minnesota, Aneela Durrani, Sagar Goyal

Turkish Journal of Veterinary & Animal Sciences

In order to determine the seroprevalence of Borrelia burgdorferi antibodies in suspected dogs in Minnesota, the present study examines the database of the Veterinary Diagnostic Laboratory at the University of Minnesota over a 10 year period (2001-June 2010). A total of 1081 serum samples from dogs suspected of having borreliosis were submitted by 112 private veterinary clinics. The samples were tested using an indirect fluorescent antibody (IFA) test. Samples with titers of =>1:320 were considered positive. The rate of seroprevalence of antibodies was 88%. The increase in the rate of yearly seroprevalence of Borrelia burgdorferi antibodies in dogs was …

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Comments On: In Vitro Efficacy Of Hyperbaric Oxygen Therapy Against Leishmania Tropica Promastigotes And Amastigotes, Yalçin Önem, Vedat Turhan Jan 2012

Comments On: In Vitro Efficacy Of Hyperbaric Oxygen Therapy Against Leishmania Tropica Promastigotes And Amastigotes, Yalçin Önem, Vedat Turhan

Turkish Journal of Medical Sciences

No abstract provided.

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The Role Of Quantitative D-Dimer Levels In The Follow-Up And Differential Diagnosis Of Pulmonary Thromboembolism And Community-Acquired Pneumonia, Ayhan Varol, Nurdan Köktürk, Hati̇ce Kiliç, Müge Aydoğdu, Numan Nadi̇r Eki̇m Jan 2012

The Role Of Quantitative D-Dimer Levels In The Follow-Up And Differential Diagnosis Of Pulmonary Thromboembolism And Community-Acquired Pneumonia, Ayhan Varol, Nurdan Köktürk, Hati̇ce Kiliç, Müge Aydoğdu, Numan Nadi̇r Eki̇m

Turkish Journal of Medical Sciences

Aim: To identify the quantitative D-dimer levels in pulmonary thromboembolism (PTE) and hospitalized-community acquired pneumonia (CAP) patients, and to determine the alteration of D-dimer levels with anticoagulant or antibacterial therapy. It is not well known that the quantitative analysis of D-dimer has a role in the differential diagnosis of PTE from other diseases. Materials and methods: Serum D-dimer levels were measured and compared prospectively with a latex-enhanced immunoturbidimetric method at admission, before initiating any antibiotic or anticoagulant therapy and then at days 3, 10, and 30 of treatment in PTE and CAP patients. Results: A total of 80 patients (45 …

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High Cerebrospinal Fluid Protein Level In West Nile Virus Ncephalitis: Report Of Five Cases, Oğuz Karabay, Nazan Tuna, Mehmet Yahyaoğlu, Gökçen Kayan Jan 2012

High Cerebrospinal Fluid Protein Level In West Nile Virus Ncephalitis: Report Of Five Cases, Oğuz Karabay, Nazan Tuna, Mehmet Yahyaoğlu, Gökçen Kayan

Turkish Journal of Medical Sciences

An outbreak of West Nile virus (WNV) occurred in Greece, Russia, and Turkey in 2010. We diagnosed 5 WNV encephalitis patients, who presented with high cerebrospinal fluid (CSF) protein level and encephalitis relevant symptoms in the last days of summer or in the first days of autumn. Here, we aimed to present a retrospective analysis of 5 WNV encephalitis cases in Turkey in terms of their clinical and laboratory findings.

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Risk Factors For Mortality In Patients With Nosocomial Staphylococcus Aureus Bacteremia, Ali̇ye Baştuğ, Gülruhsar Yilmaz, Bi̇rcan Kayaaslan, Esragül Akinci, Hurrem Bodur Jan 2012

Risk Factors For Mortality In Patients With Nosocomial Staphylococcus Aureus Bacteremia, Ali̇ye Baştuğ, Gülruhsar Yilmaz, Bi̇rcan Kayaaslan, Esragül Akinci, Hurrem Bodur

Turkish Journal of Medical Sciences

Bloodstream infections (BSIs) due to Staphylococcus aureus have become increasingly common in hospitals worldwide. The aim of this study was to evaluate the risk factors for mortality of nosocomial BSI due to S. aureus. Materials and methods: We analyzed risk factors for mortality of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) bacteremia in a prospective case control study in a 1196-bed tertiary referral medical center. Logistic regression analyses were used to determine risk factors and prognostic factors of mortality. Results: Between July 2006 and January 2009, 176 patients were identified with clinically significant and microbiologically confirmed nosocomial bacteremia …

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Tax Deductions For Charitable Contributions: Domestic Activities, Foreign Activities, Or None Of The Above, Eric M. Zolt Jan 2012

Tax Deductions For Charitable Contributions: Domestic Activities, Foreign Activities, Or None Of The Above, Eric M. Zolt

UC Law Journal

Warren Buffett, Bill Gates, and sixty-seven other billionaires have pledged to give a majority of their wealth for charitable purposes. The total dollar amount of potential funding for charitable activities is staggering. So is the potential loss of tax revenue. Because of past, current, and future tax benefits, U.S. taxpayers have funded and will fund a substantial portion of these charitable activities without any input in how the money is spent. These billionaires are not just being generous with their own money, but with the money of the American people. Should we allow tax benefits to subsidize charitable activities and …

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