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2011

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Articles 15031 - 15060 of 20343

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Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel Jan 2011

Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel

Open Access Publications

No abstract provided.


Identification Of Dhx33 As A Mediator Of Rrna Synthesis And Cell Growth, Yandong Zhang, Jason T. Forys, Alexander P. Miceli, Abigail S. Gwinn, Jason D. Weber Jan 2011

Identification Of Dhx33 As A Mediator Of Rrna Synthesis And Cell Growth, Yandong Zhang, Jason T. Forys, Alexander P. Miceli, Abigail S. Gwinn, Jason D. Weber

Open Access Publications

No abstract provided.


Statistical Analysis And Interpretation Of Prenatal Diagnostic Imaging Studies, Part 2: Descriptive And Inferential Statistical Methods, Methodius G. Tuuli, Anthony O. Odibo Jan 2011

Statistical Analysis And Interpretation Of Prenatal Diagnostic Imaging Studies, Part 2: Descriptive And Inferential Statistical Methods, Methodius G. Tuuli, Anthony O. Odibo

Open Access Publications

No abstract provided.


Sequencing A Mouse Acute Promyelocytic Leukemia Genome Reveals Genetic Events Relevant For Disease Progression, Lukas D. Wartman, David E. Larson, Zhifu Xiang, Li Ding, Ken Chen, Ling Lin, Patrick Cahan, Jeffery M. Klco, John S. Welch, Cheng Li, Jacqueline E. Payton, Geoffrey L. Uy, Nobish Varghese, Rhonda E. Ries, Et Al. Jan 2011

Sequencing A Mouse Acute Promyelocytic Leukemia Genome Reveals Genetic Events Relevant For Disease Progression, Lukas D. Wartman, David E. Larson, Zhifu Xiang, Li Ding, Ken Chen, Ling Lin, Patrick Cahan, Jeffery M. Klco, John S. Welch, Cheng Li, Jacqueline E. Payton, Geoffrey L. Uy, Nobish Varghese, Rhonda E. Ries, Et Al.

Open Access Publications

No abstract provided.


Structural Correlates Of Cytoplasmic And Chloroplast Lipid Body Synthesis In Chlamydomonas Reinhardtii And Stimulation Of Lipid Body Production With Acetate Boost, Carrie Goodson, Robyn Roth, Zi Teng Wang, Ursula Goodenough Jan 2011

Structural Correlates Of Cytoplasmic And Chloroplast Lipid Body Synthesis In Chlamydomonas Reinhardtii And Stimulation Of Lipid Body Production With Acetate Boost, Carrie Goodson, Robyn Roth, Zi Teng Wang, Ursula Goodenough

Open Access Publications

No abstract provided.


The Transcriptional Diversity Of 25 Drosophila Cell Lines, Marijke J. Van Baren, Laura Langton, Aaron E. Tenney, Michael R. Brent Jan 2011

The Transcriptional Diversity Of 25 Drosophila Cell Lines, Marijke J. Van Baren, Laura Langton, Aaron E. Tenney, Michael R. Brent

Open Access Publications

No abstract provided.


Chimeric 16s Rrna Sequence Formation And Detection In Sanger And 454-Pyrosequenced Pcr Amplicons, Erica Sodergren, Et Al Jan 2011

Chimeric 16s Rrna Sequence Formation And Detection In Sanger And 454-Pyrosequenced Pcr Amplicons, Erica Sodergren, Et Al

Open Access Publications

No abstract provided.


Biome Representational In Silico Karyotyping, Valliammai Muthappan, Aaron Y. Lee, Tamara L. Lamprecht, Lakshmi Akileswaran, Suzanne M. Dintzis, Choli Lee, Vincent Magrini, Elaine R. Mardis, Jay Shendure, Russell N. Van Gelder Jan 2011

Biome Representational In Silico Karyotyping, Valliammai Muthappan, Aaron Y. Lee, Tamara L. Lamprecht, Lakshmi Akileswaran, Suzanne M. Dintzis, Choli Lee, Vincent Magrini, Elaine R. Mardis, Jay Shendure, Russell N. Van Gelder

Open Access Publications

No abstract provided.


The Genetic Association Between Personality And Major Depression Or Bipolar Disorder. A Polygenic Score Analysis Using Genome-Wide Association Data, P. A. F. Madden, A. C. Heath, M. L. Pergadia, A. Agrawal, P. Lin, R. A. Grucza, L. J. Bierut, Et Al Jan 2011

The Genetic Association Between Personality And Major Depression Or Bipolar Disorder. A Polygenic Score Analysis Using Genome-Wide Association Data, P. A. F. Madden, A. C. Heath, M. L. Pergadia, A. Agrawal, P. Lin, R. A. Grucza, L. J. Bierut, Et Al

Open Access Publications

No abstract provided.


Investigation Of A Pharmaceutical Compound With Artificial Streams: Effects Of The Antihistamine Cimetidine On Stream Ecosystem Function., Paul David Hoppe Jan 2011

Investigation Of A Pharmaceutical Compound With Artificial Streams: Effects Of The Antihistamine Cimetidine On Stream Ecosystem Function., Paul David Hoppe

Master's Theses

Pharmaceutical compounds have been widely detected in surface waters but their effects on stream ecosystems are unknown. Cimetidine (Tagamet®), a widely used H2 histamine antagonist has been detected in surface waters. To measure chronic effects of cimetidine on stream invertebrates, I conducted a long-term (83d) artificial-stream experiment. A range of cimetidine concentrations (0.07 μg L-1 to 70.0 μg L-1) were added to streams supporting populations of the amphipod Gammarus fasciatus and beetle Psephenus herricki. P. herricki individual growth rates were reduced in the presence of cimetidine, but G. fasciatus individual growth rates were not different among treatments. G. fasciatus size …


A Study Of Mo(4+)Quinoxalyl-Dithiolenes As Models For The Non-Innocent Pyranopterin In The Molybdenum Cofactor, Kelly G. Matz, Regina P. Mte, Rebecca Rothstein, Martin L. Kirk, Sharon J. Nieter Burgmayer Jan 2011

A Study Of Mo(4+)Quinoxalyl-Dithiolenes As Models For The Non-Innocent Pyranopterin In The Molybdenum Cofactor, Kelly G. Matz, Regina P. Mte, Rebecca Rothstein, Martin L. Kirk, Sharon J. Nieter Burgmayer

Chemistry Faculty Research and Scholarship

A model system for the molybdenum cofactor has been developed that illustrates the noninnocent behavior of an N-heterocycle appended to a dithiolene chelate on molybdenum. The pyranopterin of the molybdenum cofactor is modeled by a quinoxalyldithiolene ligand (S(2)BMOQO) formed from the reaction of molybdenum tetrasulfide and quinoxalylalkyne. The resulting complexes TEA[Tp*MoX(S(2)BMOQO)] [1, X = S; 3, X = O; TEA = tetraethylammonium; Tp* = hydrotris(3,5-dimethylpyrazolyl)borate] undergo a dehydration-driven intramolecular cyclization within quinoxalyldithiolene, forming Tp*MoX(pyrrolo-S(2)BMOQO) (2, X = S; 4, X = O). 4 can be oxidized by one electron to produce the molybdenum(5+) complex 5. In a preliminary report of …


Pterin Chemistry And Its Relationship To The Molybdenum Cofactor, Partha Basu, Sharon J. Nieter Burgmayer Jan 2011

Pterin Chemistry And Its Relationship To The Molybdenum Cofactor, Partha Basu, Sharon J. Nieter Burgmayer

Chemistry Faculty Research and Scholarship

The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to perform a variety of biological functions. This article describes the basic nomenclature of pterin, their biological roles, structure, chemical synthesis and redox reactivity. In addition, the biosynthesis of pterin sand current models of the molybdenum cofactor are discussed.


Video-Rate Fluorescence Diffuse Optical Tomography For In Vivo Sentinel Lymph Node Imaging, Metasebya Solomon, Brian R. White, Ralph E. Nothdruft, Walter Akers, Gail Sudlow, Adam T. Eggebrecht, Samuel Achilefu, Joseph P. Culver Jan 2011

Video-Rate Fluorescence Diffuse Optical Tomography For In Vivo Sentinel Lymph Node Imaging, Metasebya Solomon, Brian R. White, Ralph E. Nothdruft, Walter Akers, Gail Sudlow, Adam T. Eggebrecht, Samuel Achilefu, Joseph P. Culver

Open Access Publications

No abstract provided.


Study Of Rotational Dynamics Of Receptor-Targeted Contrast Agents In Cancerous And Normal Prostate Tissues Using Time-Resolved Picosecond Emission Spectroscopy, Yang Pu, Wubao B. Wang, Samuel Achilefu, Robert R. Alfano Jan 2011

Study Of Rotational Dynamics Of Receptor-Targeted Contrast Agents In Cancerous And Normal Prostate Tissues Using Time-Resolved Picosecond Emission Spectroscopy, Yang Pu, Wubao B. Wang, Samuel Achilefu, Robert R. Alfano

Open Access Publications

No abstract provided.


Tnf-Stimulated Map Kinase Activation Mediated By A Rho Family Gtpase Signaling Pathway, Shashi Kant, Wojciech Swat, Sheng Zhang, Zhong-Yin Zhang, Benjamin G. Neel, Richard A. Flavell Jan 2011

Tnf-Stimulated Map Kinase Activation Mediated By A Rho Family Gtpase Signaling Pathway, Shashi Kant, Wojciech Swat, Sheng Zhang, Zhong-Yin Zhang, Benjamin G. Neel, Richard A. Flavell

Open Access Publications

No abstract provided.


Fine-Tuning P53 Activity Through C-Terminal Modification Significantly Contributes To Hsc Homeostasis And Mouse Radiosensitivity, Yunyuan V. Wang, Mathias Leblanc, Norma Fox, Jian-Hua Mao, Kelsey L. Tinkum, Kurt Krummel, Dannielle Engle, David Piwnica-Worms, Helen Piwnica-Worms, Allan Balmain, Kenneth Kaushanszy, Geoffrey M. Wahl Jan 2011

Fine-Tuning P53 Activity Through C-Terminal Modification Significantly Contributes To Hsc Homeostasis And Mouse Radiosensitivity, Yunyuan V. Wang, Mathias Leblanc, Norma Fox, Jian-Hua Mao, Kelsey L. Tinkum, Kurt Krummel, Dannielle Engle, David Piwnica-Worms, Helen Piwnica-Worms, Allan Balmain, Kenneth Kaushanszy, Geoffrey M. Wahl

Open Access Publications

No abstract provided.


The Nuclear Receptor Pparβ/Δ Programs Muscle Glucose Metabolism In Cooperation With Ampk And Mef2, Zhenji Gan, Eileen M. Burkart-Hartman, Dong-Ho Han, Brian Finck, Teresa C. Leone, Emily Y. Smith, Julio E. Ayala, John Holloszy, Daniel P. Kelly Jan 2011

The Nuclear Receptor Pparβ/Δ Programs Muscle Glucose Metabolism In Cooperation With Ampk And Mef2, Zhenji Gan, Eileen M. Burkart-Hartman, Dong-Ho Han, Brian Finck, Teresa C. Leone, Emily Y. Smith, Julio E. Ayala, John Holloszy, Daniel P. Kelly

Open Access Publications

No abstract provided.


The Parkinsonian Mimetic, Mpp+, Specifically Impairs Mitochondrial Transport In Dopamine Axons, Jeong S. Kim-Han, Jo Ann Antenor-Dorsey, Karen L. O'Malley Jan 2011

The Parkinsonian Mimetic, Mpp+, Specifically Impairs Mitochondrial Transport In Dopamine Axons, Jeong S. Kim-Han, Jo Ann Antenor-Dorsey, Karen L. O'Malley

Open Access Publications

No abstract provided.


The Mammalian Cone Visual Cycle Promotes Rapid M/L-Cone Pigment Regeneration Independently Of The Interphotoreceptor Retinoid-Binding Protein, Alexander V. Kolesnikov, Peter H. Tang, Ryan O. Parker, Rosalie K. Crouch, Vladimir J. Kefalov Jan 2011

The Mammalian Cone Visual Cycle Promotes Rapid M/L-Cone Pigment Regeneration Independently Of The Interphotoreceptor Retinoid-Binding Protein, Alexander V. Kolesnikov, Peter H. Tang, Ryan O. Parker, Rosalie K. Crouch, Vladimir J. Kefalov

Open Access Publications

No abstract provided.


Critical Role Of Astroglial Apolipoprotein E And Liver X Receptor-Α Expression For Microglial Aβ Phagocytosis, Dick Terwel, Knut R. Steffensen, Philip B. Verghese, Markus P. Kummer, Jan-Åke Gustafsson, David M. Holtzman, Michael T. Heneka Jan 2011

Critical Role Of Astroglial Apolipoprotein E And Liver X Receptor-Α Expression For Microglial Aβ Phagocytosis, Dick Terwel, Knut R. Steffensen, Philip B. Verghese, Markus P. Kummer, Jan-Åke Gustafsson, David M. Holtzman, Michael T. Heneka

Open Access Publications

No abstract provided.


Specification Of A Foxj1-Dependent Lineage In The Forebrain Is Required For Embryonic-To-Postnatal Transition Of Neurogenesis In The Olfactory Bulb, Benoit V. Jacquet, Nagendran Muthusamy, Laura J. Sommerville, Guanxi Xiao, Huixuan Liang, Yong Zhang, Michael J. Holtzman, H. T. Ghashghaei Jan 2011

Specification Of A Foxj1-Dependent Lineage In The Forebrain Is Required For Embryonic-To-Postnatal Transition Of Neurogenesis In The Olfactory Bulb, Benoit V. Jacquet, Nagendran Muthusamy, Laura J. Sommerville, Guanxi Xiao, Huixuan Liang, Yong Zhang, Michael J. Holtzman, H. T. Ghashghaei

Open Access Publications

No abstract provided.


A Sensitive High-Throughput Assay For Evaluating Host-Pathogen Interactions In Cryptococcus Neoformans Infection, Deepa Srikanta, Meng Yang, Matthew Williams, Tamara L. Doering Jan 2011

A Sensitive High-Throughput Assay For Evaluating Host-Pathogen Interactions In Cryptococcus Neoformans Infection, Deepa Srikanta, Meng Yang, Matthew Williams, Tamara L. Doering

Open Access Publications

No abstract provided.


Toward An Interactive Article: Integrating Journals And Biological Databases, Arun Rangarajan, Tim Schedl, Karen Yook, Juancarlos Chan, Stephen Haenel, Lolly Otis, Sharon Faelten, Tracey Depellegrin-Connelly, Ruth Isaacson, Marek S. Skrzypek, Steven J. Marygold, Raymund Raymund, J Michael Cherry, Paul W. Sternberg, Hans-Michael Müller Jan 2011

Toward An Interactive Article: Integrating Journals And Biological Databases, Arun Rangarajan, Tim Schedl, Karen Yook, Juancarlos Chan, Stephen Haenel, Lolly Otis, Sharon Faelten, Tracey Depellegrin-Connelly, Ruth Isaacson, Marek S. Skrzypek, Steven J. Marygold, Raymund Raymund, J Michael Cherry, Paul W. Sternberg, Hans-Michael Müller

Open Access Publications

No abstract provided.


Lung Transplantation For Pulmonary Fibrosis In Dyskeratosis Congenita: Case Report And Systematic Literature Review, Neelam Giri, Rees Lee, Albert Faro, Charles B. Huddleston, Frances V. White, Blanche P. Alter, Sharon A. Savage Jan 2011

Lung Transplantation For Pulmonary Fibrosis In Dyskeratosis Congenita: Case Report And Systematic Literature Review, Neelam Giri, Rees Lee, Albert Faro, Charles B. Huddleston, Frances V. White, Blanche P. Alter, Sharon A. Savage

Open Access Publications

No abstract provided.


Identification Of Transcriptional Regulatory Networks Specific To Pilocytic Astrocytoma, Hrishikesh Deshmukh, Jinsheng Yu, Jahangheer Shaik, Tobey J. Macdonald, Arie Perry, Jacqueline E. Payton, David H. Gutmann, Mark A. Watson, Rakesh Nagarajan Jan 2011

Identification Of Transcriptional Regulatory Networks Specific To Pilocytic Astrocytoma, Hrishikesh Deshmukh, Jinsheng Yu, Jahangheer Shaik, Tobey J. Macdonald, Arie Perry, Jacqueline E. Payton, David H. Gutmann, Mark A. Watson, Rakesh Nagarajan

Open Access Publications

No abstract provided.


Opposing Synaptic Regulation Of Amyloid-Β Metabolism By Nmda Receptors In Vivo, Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, John R. Cirrito Jan 2011

Opposing Synaptic Regulation Of Amyloid-Β Metabolism By Nmda Receptors In Vivo, Deborah K. Verges, Jessica L. Restivo, Whitney D. Goebel, David M. Holtzman, John R. Cirrito

Open Access Publications

No abstract provided.


Hiv Protease Inhibitors Act As Competitive Inhibitors Of The Cytoplasmic Glucose Binding Site Of Gluts With Differing Affinities For Glut1 And Glut4, Richard C. Hresko, Paul W. Hruz Jan 2011

Hiv Protease Inhibitors Act As Competitive Inhibitors Of The Cytoplasmic Glucose Binding Site Of Gluts With Differing Affinities For Glut1 And Glut4, Richard C. Hresko, Paul W. Hruz

Open Access Publications

No abstract provided.


Exenatide Improves Glucose Homeostasis And Prolongs Survival In A Murine Model Of Dilated Cardiomyopathy, Arpita Kalla Vyas, Kai-Chen Yang, Dennis Woo, Anatoly Tzekov, Attila Kovacs, Patrick Y. Jay, Paul W. Hruz Jan 2011

Exenatide Improves Glucose Homeostasis And Prolongs Survival In A Murine Model Of Dilated Cardiomyopathy, Arpita Kalla Vyas, Kai-Chen Yang, Dennis Woo, Anatoly Tzekov, Attila Kovacs, Patrick Y. Jay, Paul W. Hruz

Open Access Publications

No abstract provided.


Actin Depolymerizing Factor Controls Actin Turnover And Gliding Motility In Toxoplasma Gondii, Simren Mehta, L. David Sibley Jan 2011

Actin Depolymerizing Factor Controls Actin Turnover And Gliding Motility In Toxoplasma Gondii, Simren Mehta, L. David Sibley

Open Access Publications

No abstract provided.


Genetic Variants In Lpl, Oasl And Tomm40/Apoe-C1-C2-C4 Genes Are Associated With Multiple Cardiovascular-Related Traits, Rita Ps Middelberg, Manuel Ar Ferreira, Anjali K. Henders, Andrew C. Heath, Pamela Af Madden, Grant W. Montgomery, Nicholas G. Martin, John B. Whitfield Jan 2011

Genetic Variants In Lpl, Oasl And Tomm40/Apoe-C1-C2-C4 Genes Are Associated With Multiple Cardiovascular-Related Traits, Rita Ps Middelberg, Manuel Ar Ferreira, Anjali K. Henders, Andrew C. Heath, Pamela Af Madden, Grant W. Montgomery, Nicholas G. Martin, John B. Whitfield

Open Access Publications

No abstract provided.