Digital Commons Network^™

2011 Annual Report Usf System, Usf

USF Accountability Reports

No abstract provided.

2011 Work Plan Usf System, Usf

USF Accountability Reports

No abstract provided.

Thiol Peroxidases Mediate Specific Genome-Wide Regulation Of Gene Expression In Response To Hydrogen Peroxide, Dmitri E. Fomenko, Ahmet Koc, Natalia Agisheva, Michael Jacobsen, Alaattin Kaya, Mikalai Malinouski, Julian C. Rutherford, Kam-Leung Siu, Dong-Yan Jin, Dennis R. Winge, Vadim N. Gladyshev

Department of Biochemistry: Faculty Publications

Hydrogen peroxide is thought to regulate cellular processes by direct oxidation of numerous cellular proteins, whereas antioxidants, most notably thiol peroxidases, are thought to reduce peroxides and inhibit H₂O₂ response. However, thiol peroxidases have also been implicated in activation of transcription factors and signaling. It remains unclear if these enzymes stimulate or inhibit redox regulation and whether this regulation is widespread or limited to a few cellular components. Herein, we found that Saccharomyces cerevisiae cells lacking all eight thiol peroxidases were viable and withstood redox stresses. They transcriptionally responded to various redox treatments, but were unable to …

Focus Emu, May 10, 2011, Office Of Public Information

Focus EMU

No abstract provided.

Focus Emu, March 29, 2011, Office Of Public Information

Focus EMU

No abstract provided.

Focus Emu, April 5, 2011, Office Of Public Information

Focus EMU

No abstract provided.

2011 Annual Report, Office Of Research Development

ORDA Annual Reports​

No abstract provided.

Faces Of Research At Loma Linda University Health, Loma Linda University

Scope

In this issue . . .

2 | ICE on the summit
Innovative study takes ischemic pre-conditioning to new heights

6 |The science behind caring for others
Nursing professor looks at placement decisions in caregiving

8 | A voice for the children
Loma Linda researcher looks at ways to better help maltreated children

10 | The explanation of exploitation
Investigating the issues behind human trafficking in Thailand

14 | A risky ride
Study suggests higher risk of amputation in multi-rider ATV accidents

16 | Saving the sea turtles
Loma Linda researcher works to save hawksbill turtles and their habitat

18 …

Research, Monitoring, Assessment And Development Plan 2010 – 2011, Department Of Fisheries

Fisheries Occasional Publications

No abstract provided.

Laser-Induced Breakdown Spectroscopy (Libs): An Innovative Tool For Studying Bacteria, Qassem I. Mohaidat

Wayne State University Dissertations

Laser-induced breakdown spectroscopy (LIBS) has gained a reputation as a flexible and convenient technique for rapidly determining the elemental composition of samples with minimal or no sample preparation. In this dissertation, I will describe the benefits of using LIBS for the rapid discrimination and identification of bacteria (both pathogenic and non-pathogenic) based on the relative concentration of trace inorganic elements such as Mg, P, Ca, and Na. The speed, portability, and robustness of the technique suggest that LIBS may be applicable as a rapid point-of-care medical diagnostic technology.

LIBS spectra of multiple genera of bacteria such as Escherichia, Streptococcus, Mycobacterium, …

A Multi-Species Analysis Of Biomechanical Responses Of The Head To A Shock Wave, Richard Bolander

Wayne State University Dissertations

Shock wave induced brain injury remains a field of research that has great consequences for the rehabilitation of soldiers and civilians that are exposed to an explosion. As such, for the research to be successful in developing strategies to mitigate the effects of these injuries, appropriate research methods need to be developed. Animal models are currently employed to understand the brain's response to a shock wave exposure. Unfortunately no criteria have been established that indicates in what way the mechanical inputs that the cells in an animal's brain are subjected to are similar to a human. The purpose of this …

The Relationship Between Study Abroad And Motivation, Attitude And Anxiety In University Students Learning A Foreign Language, Stefania Gabriella Morreale

Wayne State University Dissertations

The objective of this dissertation was to discover the program effects of long- and short-term study abroad for university students at a midwestern, public university. Affective outcomes, such as motivation, attitude and anxiety, were examined using Gardner's Attitudes and Motivational Test Battery (AMTB) survey and a student demographic questionnaire. Quantitative data from the student demographic survey reported that the typical foreign language student surveyed is female, between the ages of 18-22, a junior, a liberal arts major with non-native fluency in the target language. The typical study abroad program attended by this sample is: short-term (less than eight weeks), most …

Analysis Of Gaba And Glutamate In The Mouse Dorsal Striatum, Stella Wisidagamage

Wayne State University Theses

ABSTRACT

ANALYSIS OF GABA AND GLUTAMATE IN MICE BRAIN

by

STELLA WISIDAGAMA

May 2011

Advisor: Dr. Tiffany Mathews

Major: Chemistry (Analytical)

Degree: Master of Science

GABA and glutamate are the predominant inhibitory and excitatory amino acid neurotransmitters in the central nervous system (CNS), respectively. However, their altered levels cause several neurological diseases including Parkinson's and Huntington's disease, schizophrenia, and epilepsy. It is important to measure their levels in the extra- and intracellular environments to better understand and develop improved therapeutics that will treat these neurological disorders. The principle aim of this study is to study the impacts of different endogenous …

Supercritical Carbon Dioxide-Processed Resorbable Polymer Nanocomposites For Bone Graft Substitute Applications, Kevin Baker

Wayne State University Dissertations

Numerous clinical situations necessitate the use of bone graft materials to enhance bone formation. While autologous and allogenic materials are considered the gold standards in the setting of fracture healing and spine fusion, their disadvantages, which include donor site morbidity and finite supply have stimulated research and development of novel bone graft substitute materials. Among the most promising candidate materials are resorbable polymers, composed of lactic and/or glycolic acid. While the characteristics of these materials, such as predictable degradation kinetics and biocompatibility, make them an excellent choice for bone graft substitute applications, they lack mechanical strength when synthesized with the …

Computational Simulation Of Skull Fracture Patterns In Pediatric Subjects Using A Porcine Model, Christina Devito Wagner

Wayne State University Dissertations

In cases of suspected child abuse with skeletal trauma, it is often the role of the injury biomechanist, forensic pathologist, clinical radiologist, and forensic anthropologist to determine the mechanism of injury when the child victims cannot speak for themselves. This is a challenging task, especially for the head, as comprehensive biomechanical data on skull fracture in infants and children do not currently exist, and frequently the determination regarding cause of injury is based on anecdotal evidence from the medical literature and unsubstantiated eyewitness accounts. The current process may result in unreliable autopsy interpretation and miscarriages of justice due to a …

Table Of Contents, Loyola University Chicago Law Journal

Loyola University Chicago Law Journal

No abstract provided.

A New Hepato-Protective Flavone Glycoside From The Flowers Of Onopordum Alexandrinum Growing In Egypt, Maha Salama, Shahira Mohammed Ezzat

Pharmacy

A bioactivity-guided fractionation of the ethyl acetate fraction of the flowers of Onopordum alexandrinum L. (Asteraceae) yielded a new flavonoidal glycoside designated as acacetin-7-O-galacturonide (9), alongside with nine known flavonoids; 6-methoxy-apigenin (hispidulin) (1), acacetin (2), apigenin (3), luteolin (4), kaempferol (5), eriodictyol (6), apigenin-7-O-glucoside (7), luteolin-7-O-glucoside (8), and kaempferol-3-O-rutinoside (10). The compounds were assayed for their hepatoprotective activity against CCl4-induced hepatic cell damage in rats and free radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl (DPPH). Compounds 4, 6, 9, and 10 have not been previously reported from flowers of O. alexandrinum L., and this is the first report of acacetin-7-O-galacturonide (9) in …

A Perfusion Mri Study Of Emotional Valence And Arousal In Parkinson's Disease, Sunsern Limsoontarakul, Meghan C. Campbell, Kevin J. Black

Open Access Publications

No abstract provided.

More Than 200 Genes Required For Methane Formation From H₂ And Co₂ And Energy Conservation Are Present In Methanothermobacter Marburgensis And Methanothermobacter Thermautotrophicus, Anne-Kristin Kaster, Meike Goenrich, Henning Seedorf, Heiko Liesegang, Antje Wollherr, Gerhard Gottschalk, Rudolf K. Thauer

Open Access Publications

No abstract provided.

Cxcr7 Antagonism Prevents Axonal Injury During Experimental Autoimmune Encephalomyelitis As Revealed By In Vivo Axial Diffusivity, Lillian Cruz-Orengo, Ying-Jr Chen, Joong Hee Kim, Denise Dorsey, Sheng-Kwei Song, Robyn S. Klein

Open Access Publications

No abstract provided.

Engraftment Of Insulin-Producing Cells From Porcine Islets In Non-Immune-Suppressed Rats Or Nonhuman Primates Transplanted Previously With Embryonic Pig Pancreas, Marc R. Hammerman

Open Access Publications

No abstract provided.

Diagnosis And Management Of Fetal Growth Restriction, Jacqueline E. A. K. Bamfo, Anthony O. Odibo

Open Access Publications

No abstract provided.

An Evolutionary Genomic Approach To Identify Genes Involved In Human Birth Timing, Jevon Plunkett, Scott Doniger, Guilherme Orabona, Thomas Morgan, Ritva Haataja, Mikko Hallman, Hilkka Puttonen, Ramkumar Menon, Edward Kuczynski, Errol Norwitz, Victoria Snegovskikh, Aarno Palotie, Leena Peltonen, Vineta Fellman, Emily A. Defranco, Bimal P. Chaudhari, Tracy L. Mcgregor, Jude J. Mcelroy, Matthew T. Oetjens, Kari Teramo, Ingrid Borecki, Justin Fay, Louis Muglia

Open Access Publications

No abstract provided.

Dynamic Analysis Of Amyloid Β-Protein In Behaving Mice Reveals Opposing Changes In Isf Versus Parenchymal Aβ During Age-Related Plaque Formation, Soyon Hong, Omar Quintero-Monzon, Beth L. Ostaszewski, Daniel R. Podlisny, William T. Cavanaugh, Ting Yang, David M. Holtzman, John R. Cirrito, Dennis J. Selkoe

Open Access Publications

No abstract provided.

Micrornas Modulate Schwann Cell Response To Nerve Injury By Reinforcing Transcriptional Silencing Of Dedifferentiation-Related Genes, Andreu Viader, Li-Wei Chang, Timothy Fahrner, Rakesh Nagarajan, Jeffrey Milbrandt

Open Access Publications

No abstract provided.

Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel

Open Access Publications

No abstract provided.

Identification Of Dhx33 As A Mediator Of Rrna Synthesis And Cell Growth, Yandong Zhang, Jason T. Forys, Alexander P. Miceli, Abigail S. Gwinn, Jason D. Weber

Open Access Publications

No abstract provided.

Statistical Analysis And Interpretation Of Prenatal Diagnostic Imaging Studies, Part 2: Descriptive And Inferential Statistical Methods, Methodius G. Tuuli, Anthony O. Odibo

Open Access Publications

No abstract provided.

Sequencing A Mouse Acute Promyelocytic Leukemia Genome Reveals Genetic Events Relevant For Disease Progression, Lukas D. Wartman, David E. Larson, Zhifu Xiang, Li Ding, Ken Chen, Ling Lin, Patrick Cahan, Jeffery M. Klco, John S. Welch, Cheng Li, Jacqueline E. Payton, Geoffrey L. Uy, Nobish Varghese, Rhonda E. Ries, Et Al.

Open Access Publications

No abstract provided.

Structural Correlates Of Cytoplasmic And Chloroplast Lipid Body Synthesis In Chlamydomonas Reinhardtii And Stimulation Of Lipid Body Production With Acetate Boost, Carrie Goodson, Robyn Roth, Zi Teng Wang, Ursula Goodenough

Open Access Publications

No abstract provided.