Digital Commons Network^™

Get M.A.D.D.: America's Battle To Overcome Drunk Driving, Elizabeth Martinez

Honors Thesis and Capstone Projects

No abstract provided.

Monitor Newsletter November 22, 2010, Bowling Green State University

Monitor

Official Publication of Bowling Green State University for Faculty and Staff

The Daily Egyptian, November 22, 2010, Daily Egyptian Staff

November 2010

No abstract provided.

November 22, 2010 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Savings Outcomes Of An Ida Program For Survivors Of Domestic Violence, Cynthia Sanders

Center for Social Development Research

Savings Outcomes of an IDA Program for Survivors of Domestic Violence

Interview With Michael O'Brien, Osd, 2010 (Audio), Michael O'Brien

All Sustainability History Project Oral Histories

Interview of Michael O'Brien by Ian Caputo in North Portland, Oregon on November 22nd, 2010.

The interview index is available for download.

Accounting For Disability Insurance In The Dynamic Relationship Between Disability Onset And Earnings, Perry Singleton

Economics - All Scholarship

The onset of a work-limiting disability coincides with an immediate decline in earnings with little recovery. This study examines whether this relationship is attributable to the labor disincentives of disability insurance. The data come from the Survey of Income and Program Participation linked to administrative data from the Social Security Administration. The analysis suggests that disability insurance accounts for little of the initial drop in earnings at the time of disability onset, but its effect may increase as time since disability onset elapses. The results highlight the advantages of immediate, though temporary disability benefits.

Regression Approach To Adjust Wia Performance Standards, Timothy J. Bartik, Randall W. Eberts, Kenneth J. Kline

Presentations

No abstract provided.

Safety Standards And Indigenous Products: What Role For Traditional Knowledge?, Meredith Kolsky Lewis

Contributions to Books

Published as Chapter 8 in International Economic Law and National Autonomy, Meredith Kolsky Lewis & Susy Frankel, eds.

Indigenous communities have used native plants as foods and for medicinal purposes for thousands of years. Some of these indigenous products have proven sufficiently popular that individuals outside the indigenous community have sought to consume, purchase and market them. In certain instances, new products have been derived from the indigenous plant and sold outside the indigenous community. In other cases, the indigenous product has been exported in its original form, but utilized in non-traditional ways in the export market. In recent years, …

The Role Of The Internal Market In Ireland's Economic Growth, Noel Cahill, Rory O'Donnell

Documents

No abstract provided.

Bjc Today

BJC Today

No abstract provided.

Jpm (E Goldstein) Letter To Gary Cohen Re Disclosure Of Confidential Material, Eric Goldstein

Documents

This letter is addressed to Gary J. Cohen

An Archaeal Trna-Synthetase Complex That Enhances Aminoacylation Under Extreme Conditions, Vlatka Godinic-Mikulcic, Jelena Jaric, Corinne D. Hausmann, Michael Ibba, Ivana Weygand-Durasevic

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Aminoacyl-tRNA synthetases (aaRSs) play an integral role in protein synthesis, functioning to attach the correct amino acid with its cognate tRNA molecule. AaRSs are known to associate into higher-order multi-aminoacyl-tRNA synthetase complexes (MSC) involved in archaeal and eukaryotic translation, although the precise biological role remains largely unknown. To gain further insights into archaeal MSCs, possible protein-protein interactions with the atypical Methanothermobacter thermautotrophicus seryl-tRNA synthetase (MtSerRS) were investigated. Yeast two-hybrid analysis revealed arginyl-tRNA synthetase (MtArgRS) as an interacting partner of MtSerRS. Surface plasmon resonance confirmed stable complex formation, with a dissociation constant (KD) of 250 nm. Formation of the MtSerRS·MtArgRS complex …

Ectopic T Cell Receptor-Α Locus Control Region Activity In B Cells Is Suppressed By Direct Linkage To Two Flanking Genes At Once, Stefan Knirr, Janette Gomos-Klein, Blanca E. Andino, Faith Harrow, Karl F. Erhard, Damian Kovalovsky, Derek B. Sant'angelo, Benjamin D. Ortiz

Publications and Research

The molecular mechanisms regulating the activity of the TCRα gene are required for the production of the circulating T cell repertoire. Elements of the mouse TCRα locus control region (LCR) play a role in these processes. We previously reported that TCRα LCR DNA supports a gene expression pattern that mimics proper thymus-stage, TCRα gene-like developmental regulation. It also produces transcription of linked reporter genes in peripheral T cells. However, TCRα LCR-driven transgenes display ectopic transcription in B cells in multiple reporter gene systems. The reasons for this important deviation from the normal TCRα gene regulation pattern are unclear. In its …

Infant Pain Management, Breanne Ziraldo

Senior Honors Theses

Emphasis on infant pain management has recently become prominent in the medical field. Though it was once thought that infants do not feel pain or remember pain, this thinking has changed due to recent research on the subject. This research has found that infants’ underdeveloped nervous systems actually leads to increased pain rather than decreased pain as previously thought. Research has also found that there are long-term developmental risks associated with prolonged or unmanaged pain in infancy. However, this has not been applied to clinical practice. Studies show that infants are still being under-medicated, if medicated at all, for painful …

Prophets And Pastors, David Hamstra

Memory, Meaning & Faith

No abstract provided.

Alumna Assisting Special Needs Inmates, Rachel Hatch

News and Events (Discontinued Series)

No abstract provided.

Florida Sentinel Bulletin, November 22, 2010, Gwen Hayes

Florida Sentinel Bulletin Collection

The November 22, 2010, issue of the Florida Sentinel Bulletin.

Mouse Cd8alpha+ Dcs And Human Bdca3+ Dcs Are Major Producers Of Ifn-Lambda In Response To Poly Ic., Henning Lauterbach, Barbara Bathke, Stefanie Gilles, Claudia Traidl-Hoffmann, Christian A. Luber, György Fejer, Marina A. Freudenberg, Gayle M. Davey, David Vremec, Axel Kallies, Li Wu, Ken Shortman, Paul Chaplin, Mark Suter, Meredith O'Keeffe, Hubertus Hochrein

School of Biomedical Sciences

Polyinosinic:polycytidylic acid (poly IC), a double-stranded RNA, is an effective adjuvant in vivo. IFN-λs (also termed IL-28/29) are potent immunomodulatory and antiviral cytokines. We demonstrate that poly IC injection in vivo induces large amounts of IFN-λ, which depended on hematopoietic cells and the presence of TLR3 (Toll-like receptor 3), IRF3 (IFN regulatory factor 3), IRF7, IFN-I receptor, Fms-related tyrosine kinase 3 ligand (FL), and IRF8 but not on MyD88 (myeloid differentiation factor 88), Rig-like helicases, or lymphocytes. Upon poly IC injection in vivo, the IFN-λ production by splenocytes segregated with cells phenotypically resembling CD8α(+) conventional dendritic cells (DCs [cDCs]). In …

Medical School Watercooler Newsletter - November 21, 2010, Lindsey Lyle

Watercooler Newsletter

This is the November 21, 2010 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Orthopaedic Department Receives Gift from HJW Foundation
• Mark your calendars
• Holiday Toy Drive - Donate Today
• Reminder for USA Health & Dental Plan Members

Deafdigest: Gold Edition, November 21, 2010, Barry Strassler

DeafDigest Gold 2010

No abstract provided.

Deafdigest: Blue Edition, November 21, 2010, Barry Strassler

DeafDigest Blue 2010

No abstract provided.

Vol. 61, No. 3, November 20, 2010, University Of Michigan Law School

Res Gestae

•Where in the World Were You on Wednesday? •The Beer Gal •When You Were Cooler •Sudoku •Zach Letter Law •Law & Lit •Food Court •Kicking it Old School •Nannes Challenge Results •Halloween Party Pics •Crossword

November 20, 2010 (Pages 6627-6762), Pennsylvania Legislative Reference Bureau

Volume 40 (2010)

No abstract provided.

The Murray Ledger And Times, November 20, 2010, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

11/20/2010, Slutzker Center For International Students

Newsletters from Slutzker Center for International Services - SCIS News

No abstract provided.

Examining Preschoolers' Trajectories Of Individual Learning Behaviors: The Influence Of Approaches To Learning On School Readiness, Michelle Filomena Maier

Open Access Dissertations

This study integrated variable- and child-centered techniques to investigate trajectories of four learning behaviors (initiative, persistence, planning, and problem-solving flexibility) and their influence on Head Start preschoolers' academic school readiness. Variable-centered findings revealed differential, quadratic growth trajectories for each of the four learning behaviors. However, where children began the year (intercept), how much they changed across the year (slope), and how much their rate of change changed across the year (quadratic) differed depending on the learning behavior. Initiative and problem-solving flexibility emerged as significant predictors of end-of-year academic school readiness skills, controlling for persistence and planning. There was no evidence …

Applying Ecodevelopmental Theory And The Theory Of Reasoned Action To Understand Hiv Risk Behaviors Among Hispanic Adolescents, Johis Ortega

Open Access Dissertations

The number of adolescents in the U.S. who engage in risk behaviors such as alcohol and drug use and unsafe sexual practices has reached alarming levels, with Hispanic adolescents in particular reporting high rates of substance use and sexual activity. This study explored risk and protective factors that influence high-risk behaviors in Hispanic adolescents. A theoretical model was developed based on an integration of Ecodevelopmental Theory and the Theory of Reasoned Action to investigate individual and social factors that affect the risk behaviors of Hispanic adolescents. This study was a cross-sectional, descriptive, secondary investigation of the baseline data of a …

Static And Dynamic Efficiency Of Irreversible Health Care Investments Under Alternative Payment Rules, Rosella Levaggi, Michele Moretto, Paolo Pertile

Fondazione Eni Enrico Mattei Working Papers

The paper studies the incentive for providers to invest in new health care technologies under alternative payment systems, when the patients' benefits are uncertain. If the reimbursement by the purchaser includes both a variable (per patient) and a lump-sum component, efficiency can be ensured both in the timing of adoption (dynamic) and the intensity of use of the technology (static). If the second instrument is unavailable, a trade-off may emerge between static and dynamic efficiency. In this context, we also discuss how the regulator could use the control of the level of uncertainty faced by the provider as an instrument …

Role Of Alpha 7 Nicotinic Acetylcholine Receptor In Calcium Signaling Induced By Prion Protein Interaction With Stress-Inducible Protein 1, Flavio H. Beraldo, Camila P. Arantes, Tiago G. Santos, Nicolle G. T. Queiroz, Kirk Young, Jane R. Rylett, Regina P. Markus, Marco A. M. Prado, Vilma R. Martins

Anatomy and Cell Biology Publications

The prion protein (PrP(C)) is a conserved glycosylphosphatidyl-inositol-anchored cell surface protein expressed by neurons and other cells. Stress-inducible protein 1 (STI1) binds PrP(C) extracellularly, and this activated signaling complex promotes neuronal differentiation and neuroprotection via the extracellular signal-regulated kinase 1 and 2 (ERK1/2) and cAMP-dependent protein kinase 1 (PKA) pathways. However, the mechanism by which the PrPC-STI1 interaction transduces extracellular signals to the intracellular environment is unknown. We found that in hippocampal neurons, STI1-PrP(C) engagement induces an increase in intracellular Ca(2+) levels. This effect was not detected in PrP(C)-null neurons or wild-type neurons treated with an STI1 mutant unable to …