Digital Commons Network^™

Role Of Alpha Synuclein In Noise Induced Hearing Loss, Melissa Mooney

Independent Studies and Capstones

The recent discovery of the contribution of alpha synuclein in the auditory system prompted further investigation of its functional role. Auditory brainstem response (ABR) and gap detection testing were completed on wild-type and transgenic M83 mice to assess the role of alpha synuclein in noise-induced hearing loss and central auditory function.

Marginal Cell Density In Young And Old Cba/J And Cba/Caj Mice, Ashley Dahl

Independent Studies and Capstones

The goal of the present study was to compare aging characteristics of the cochlear lateral wall in inbred mouse strains (CBA/J and CBA/CaJ) having very different endocochlear potential (EP)-versus-age profiles to see which anatomic differences might predict their EP differences.

Efficacy Of 1000 Hz Tympanometry In Infants Birth To 4 Months Of Age: A Follow Up Study, Jamie Glater

Independent Studies and Capstones

Interpretation of 1000 Hz tympanometry is not standardized. Several compensated and uncompensated measures were analyzed and compared to otologic findings. Results of auditory brainstem testing and otoacoustic emissions were considered to better obtain middle ear status. Findings were inconclusive due to small sample size.

Immunohistochemistry Of Synergistic Effects Of Kanamycin And Furosemide In The Murine Model, Katherine Gorton

Independent Studies and Capstones

Adult CBA/CaJ mice were injected with large single dose of both kanamycin and furosemide in order to study hair cell lesion and macrophage recruitment within the cochlea.

Nrxn3 Is A Novel Locus For Waist Circumference: A Genome-Wide Association Study From The Charge Consortium, Mary F. Feitosa, Aldi Kraja, Michael A. Province, Qunyuan Zhang, Ingrid B. Borecki

ICTS Faculty Publications

No abstract provided.

Klassevirus 1, A Previously Undescribed Member Of The Family Picornaviridae, Is Globally Widespread, Lori R. Holtz, Stacy R. Finkbeiner, Guoyan Zhao, Carl D. Kirkwood, Rosina Girones, James M. Pipas, David Wang

ICTS Faculty Publications

No abstract provided.

Outlook Magazine, Winter 2009

Outlook Magazine

No abstract provided.

Remarkable Creatures: Epic Adventures In The Search For The Origin Of Species By Sean B. Carroll, Houghton Mifflin Harcourt 2009, Michael Zimmerman

LAS Faculty Book Reviews

No abstract provided.

Epa's Council For Regulatory Environmental Modeling : A Case Study Of Science Policy Implementation , Genevieve M. Borg

Dissertations, Master's Theses and Master's Reports - Open

As environmental problems became more complex, policy and regulatory decisions become far more difficult to make. The use of science has become an important practice in the decision making process of many federal agencies. Many different types of scientific information are used to make decisions within the EPA, with computer models becoming especially important. Environmental models are used throughout the EPA in a variety of contexts and their predictive capacity has become highly valued in decision making.

The main focus of this research is to examine the EPA’s Council for Regulatory Modeling (CREM) as a case study in addressing science …

Robots In War: Issues Of Risk And Ethics, Patrick Lin, George A. Bekey, Keith Abney

Philosophy

War robots clearly hold tremendous advantages-from saving the lives of our own soldiers, to safely defusing roadside bombs, to operating in inaccessible and dangerous environments such as mountainside caves and underwater. Without emotions and other liabilities on the battlefield, they could conduct warfare more ethically and effectively than human soldiers who are susceptible to overreactions, anger, vengeance, fatigue, low morale, and so on. But the use of robots, especially autonomous ones, raises a a host of ethical and risk issues. This paper offers a a survey of such emerging issues in this new but rapidly advancing area of technology.

East Bayside Neighborhood Study : Prepared By The Planning Workshop, 2009 - Muskie School Of Public Service Community Planning & Development Program.

Individual Documents

Planning Workshop is an annual course offering in Muskie's Community Planning and Development Program. It brings students and clients together on community planning issues. This study was the product of the Planning Workshop 2009 and includes the group's analysis of East Bayside along with recommendations that address community concerns such as reconnecting the street grid, improving housing, and redeveloping the industrial district.

On Whether Or Not Merleau-Ponty's Phenomenology Of Lived Body Experience Can Enrich St. Thomas Aquinas's Integral Anthropology, Joshua Miller

Electronic Theses and Dissertations

I argue that Merleau-Ponty's phenomenology of lived body experience can be used to enrich Aquinas's integral anthropology. In Chapter One I lay out the possibilities of such an enrichment by examining contemporary philosophers of mind who draw on Aquinas and Merleau-Ponty in strikingly similar ways. Analytical Thomists, as represented by Eric LaRock, and thinkers seeking to integrate neuropsychology and phenomenology, like Ralph Ellis, argue that that the concept of form (taken from Aquinas and Merleau-Ponty respectively) is necessary for properly understanding the human being as an integral unity of intellectual principle and body. I then pose potential objections to my …

Demonstrating Sustainable Farm Management Systems. Final Report For Rcg05-Ord13, Tara Slaven, Francis Bright, Jodie Hawley, Joe Sherrard

Natural resources research reports

The Ord River Irrigation Area (ORIA) has a 'flow through' irrigation system. That is, irrigation water is diverted from Lake Kununurra and any waste water from the irrigation system and farms flows directly back into the river downstream. This means that any sediment, nutrient or chemicals in tailwater from farms flows straight into the river.

The Ord Land and Water Management Plan 2000 specifies goals to improve surface water quality. The goals are to reduce the load of chemical and nutrient contamination and sediment in tailwater by 40 per cent.

The aim of this project was to develop and demonstrate …

An Inventory And Condition Survey Of The Lower Murchison River Area, Western Australia, P Hennig

Technical Bulletins

The inventory and condition survey of the lower Murchison River area, undertaken by the Department of Agriculture and Food, Western Australia (DAFWA) between 2002 and 2003, describes and maps the natural resources of the region’s pastoral leasehold land. This survey report provides a baseline record of the existence and condition of the natural area’s resources, to assist with the planning and implementation of land management practices. The report identified and described the condition of soils, landforms, vegetation, habitat, ecosystems, and declared plants and animals. It also assessed the impact of pastoralism and made land management recommendations. This survey report presents …

A History And Analysis Of Laws Protecting Native American Cultures, Marilyn Phelan

Tulsa Law Review

This paper was presented at the 2009 Native American law Symposium.

Mckee Library Annual Report 2008-2009, Southern Adventist University

Annual Reports

The 2008-2009 Annual Report includes statistics on library usage, updates on renovations to the library's main floor, pictures from library events, and the newsletters.

Pacific Review Winter 2009, Alumni Association Of The University Of The Pacific

Pacific Magazine and Pacific Review

No abstract provided.

N- And C-Terminal Domains In Human Holocarboxylase Synthetase Participate In Substrate Recognition, Yousef I. Hassan, Hideaki Moriyama, Lars J. Olsen, Xin Bi, Janos Zempleni

Hideaki Moriyama Publications

Holocarboxylase synthetase (HCS) catalyzes the binding of the vitamin biotin to carboxylases and histones. Carboxylases mediate essential steps in macronutrient metabolism. For example, propionyl- CoA carboxylase (PCC) catalyzes the carboxylation of propionyl-CoA in the metabolism of oddchain fatty acids. HCS comprises four putative domains, i.e., the N-terminus, the biotin transfer/ATP binding domain, a putative linker domain, and the C-terminus. Both N- and C-termini are essential for biotinylation of carboxylases by HCS, but the exact functions of these two domains in enzyme catalysis are unknown. Here we tested the hypothesis that N- and C-termini play roles in substrate recognition by HCS. …

Phase-Transfer Catalyzed Asymmetric Synthesis Of S-Naproxen, M. A. Binkley, Michael A. Christiansen, K. H. Harper, M. B. Andrus

Chemistry and Biochemistry Faculty Presentations

This presentation explores a modified approach to Kurasoin B.

Assessing Stereotype Incongruities Using The N400 Erp Component, Katherine White, Stephen Crites Jr., Jennifer Taylor, Guadalupe Corral

Selected Works Temporary Series

Numerous discoveries regarding stereotypes have been uncovered by utilizing techniques and methods developed by cognitive psychologists. The present study continues this tradition by borrowing psychophysiological techniques used for the study of memory and language, and applying them to the study of stereotypes. In this study, participants were primed with either the gender category ’Women’ or ’Men’, followed by a word which was either consistent with gender stereotypes (e.g. Women: Nurturing) or inconsistent (e.g. Women: Aggressive). Their task was to indicate whether the words matched or did not match, according to gender stereotypes. Both response times and event-related brain potentials (ERPs) …

Nerve, Muscle, Blood, Toil, Tears, And Sweat: England’S Pioneering Biophysicist, Soldier, And Statesman, Arshad Khan

Selected Works Temporary Series

No abstract provided.

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Pdf Of All O'Dell Manuscripts, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

Selected Works Temporary Series

No abstract provided.

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Selected Works Temporary Series

No abstract provided.

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Selected Works Temporary Series

No abstract provided.