Digital Commons Network^™

Investigator Initiated Studies For The Study Coordinator: Some Protocol Issues That Warrant Special Attention, Sarah Fowler-Dixon

2009 Necessary Elements in the Fundamentals of Human Subjects Research: Investigator Initiated Studies for the Study Coordinator

No abstract provided.

Closed-Channel Block Of Bk Potassium Channels By Bbtba Requires Partial Activation, Qiong-Yao Tang, Xu-Hui Zeng, Christopher J. Lingle

Open Access Publications

No abstract provided.

The 9-Methyl Group Of Retinal Is Essential For Rapid Meta Ii Decay And Phototransduction Quenching In Red Cones, Maureen E. Estevez, Alexander V. Kolesnikov, Petri Ala-Laurila, Rosalie K. Crouch, Victor I. Govardovskii, M. Carter Cornwall

Open Access Publications

No abstract provided.

A Therapeutic Antibody Against West Nile Virus Neutralizes Infection By Blocking Fusion Within Endosomes, Bruce S. Thompson, Bastiaan Moesker, Jolanda M. Smit, Jan Wilschut, Michael S. Diamond, Daved H. Fremont

Open Access Publications

No abstract provided.

Disease-Associated Mutant Ubiquitin Causes Proteasomal Impairment And Enhances The Toxicity Of Protein Aggregates, Elizabeth M. H. Tank, Heather L. True

Open Access Publications

No abstract provided.

Evolution Of A Bacterial Regulon Controlling Virulence And Mg(2+) Homeostasis, J. Christian Perez, Dongwoo Shin, Igor Zwir, Tammy Latifi, Tricia J. Hadley, Eduardo A. Groisman

Open Access Publications

No abstract provided.

Immunopurification Of Pathological Prion Protein Aggregates, Emiliano Biasini, Laura Tapella, Susanna Mantovani, Matteo Stravalaci, Marco Gobbi, David A. Harris, Roberto Chiesa

Open Access Publications

No abstract provided.

Biomechanics Of Running Indicates Endothermy In Bipedal Dinosaurs, Herman Pontzer, Vivian Allen, John R. Hutchinson

Open Access Publications

No abstract provided.

Defects In Erbb-Dependent Establishment Of Adult Melanocyte Stem Cells Reveal Independent Origins For Embryonic And Regeneration Melanocytes, Keith A. Hultman, Erine H. Budi, Daniel C. Teasley, Andrew Y. Gottlieb, David M. Parichy, Stephen L. Johnson

Open Access Publications

No abstract provided.

Modeling The Quantitative Specificity Of Dna-Binding Proteins From Example Binding Sites, Dana S. F. Homsi, Vineet Gupta, Gary D. Stormo

Open Access Publications

No abstract provided.

A Novel Role For Stat1 In Phagosome Acidification And Natural Host Resistance To Intracellular Infection By Leishmania Major, Gerald F. Spath, Paul Schlesinger, Robert Schreiber, Stephen M. Beverley

Open Access Publications

No abstract provided.

Regulation Of The Drosophila Enhancer Of Split And Invected-Engrailed Gene Complexes By Sister Chromatid Cohesion Proteins, Cheri A. Schaaf, Ziva Misulovin, Gurmukh Sahota, Akbar M. Siddiqui, Yuri B. Schwartz, Tatyana G. Kahn, Vincenzo Pirrotta, Maria Gause, Dale Dorsett

Open Access Publications

No abstract provided.

Divergent Mechanisms Controlling Hypoxic Sensitivity And Lifespan By The Daf-2/Insulin/Igf-Receptor Pathway, Meghann E. Mabon, Barbara A. Scott, C. Michael Crowder

Open Access Publications

No abstract provided.

Helicobacter Pylori’S Plasticity Zones Are Novel Transposable Elements, Dangeruta Kersulyte, Wookon Lee, Dharmalingam Subramaniam, Shrikant Anant, Phabiola Herrera, Lilia Cabrera, Jacqueline Balqui, Orsolya Brabas, Awdhesh Kalia, Robert H. Gilman, Douglas E. Berg

Open Access Publications

No abstract provided.

Expression Of Kingella Kingae Type Iv Pili Is Regulated By Σ54, Pils, And Pilr, Thomas E. Kehl-Fie, Eric A. Porsch, Sara E. Miller, Joseph W. Stgeme Iii

Open Access Publications

No abstract provided.

Washington University School Of Medicine Bulletin, 2009

Washington University School of Medicine Bulletins

No abstract provided.

Structural Determinants Of Autoproteolysis Of The Haemophilus Influenzae Hap Autotransporter, Roma Kenjale, Guoyu Meng, Doran L. Fink, Twyla Juehne, Tomoo Ohashi, Harold P. Erickson, Gabriel Waksman, Joseph W. St. Geme Iii

Open Access Publications

No abstract provided.

Plumbing The Depths Of Urinary Tract Obstruction By Using Murine Models, Feng Chen

Open Access Publications

No abstract provided.

Requirements Of Hsp104p Activity And Sis1p Binding For Propagation Of The [Rnq+] Prion, J. Patrick Bardill, Jennifer E. Dulle, Jonathan R. Fisher, Heather L. True

Open Access Publications

No abstract provided.

Detection And Landing Behavior Of Emerald Ash Borer, Agrilus Planipennis, At Low Population Density, Melissa J. Porter

Dissertations, Master's Theses and Master's Reports - Open

The exotic emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae), was first discovered in North America in southeastern Michigan, USA, and Windsor, Ontario, Canada in 2002. Significant ash (Fraxinus spp.) mortality has been caused in areas where this insect has become well established, and new infestations continue to be discovered in several states in the United States and in Canada. This beetle is difficult to detect when it invades new areas or occurs at low density. Girdled trap tree and ground surveys have been important tools for detecting emerald ash borer populations, and more recently, purple baited prism traps …

Immobilizing Bacteriorhodopsin On A Single Electron Transistor, Karl A. Walczak

Dissertations, Master's Theses and Master's Reports - Open

As awareness of potential human and environmental impacts from toxins has increased, so has the development of innovative sensors. Bacteriorhodopsin (bR) is a light activated proton pump contained in the purple membrane (PM) of the bacteria Halobacterium salinarum. Bacteriorhodopsin is a robust protein which can function in both wet and dry states and can withstand extreme environmental conditions. A single electron transistor(SET) is a nano-scale device that exploits the quantum mechanical properties of electrons to switch on and off. SETs have tremendous potential in practical applications due to their size, ultra low power requirements, and electrometer-like sensitivity.

The main …

Physical And Sexual Violence And Incident Sexually Transmitted Infections, Jenifer E. Allsworth, Mallika Anand, Colleen A. Redding, Jeffrey F. Peipert

Open Access Publications

No abstract provided.

Human Dna2 Is A Nuclear And Mitochondrial Dna Maintenance Protein, Julien P. Duxin, Benjamin Dao, Peter Martinsson, Nina Rajala, Lionel Guittat, Judith L. Campbell, Johannes N. Spelbrink, Sheila A. Stewart

Open Access Publications

No abstract provided.

Bcl3 Interacts Cooperatively With Peroxisome Proliferator-Activated Receptor Gamma (Pparγ) Coactivator 1Α To Coactivate Nuclear Receptors Estrogen-Related Receptor Α And Pparα, John Yang, R. Sanders Williams, Daniel P. Kelly

Open Access Publications

No abstract provided.

Homodimerization Controls The Fibroblast Growth Factor 9 Subfamily’S Receptor Binding And Heparan Sulfate-Dependent Diffusion In The Extracellular Matrix, Juliya Kalinina, Sara A. Byron, Helen P. Makarenkova, Shaun K. Olsen, Anna V. Eliseenkova, William J. Larochelle, Mohanraj Dhanabal, Steven Blais, David M. Ornitz, Loren A. Day, Thomas A. Neubert, Pamela M. Pollock, Moosa Mohammadi

Open Access Publications

No abstract provided.

Serine 58 Of 14-3-3Ζ Is A Molecular Switch Regulating Ask1 And Oxidant Stress-Induced Cell Death, Jibin Zhou, Zhili Shao, Risto Kerkela, Hidenori Ichijo, Anthony J. Muslin, Celia Pombo, Thomas Force

Open Access Publications

No abstract provided.

Targeted Knock-In Mice Expressing Mutations Of Cd28 Reveal An Essential Pathway For Costimulation, Lindzy F. Dodson, Jonathan S. Boomer, Christine M. Deppong, Dulari D. Shah, Julia Sim, Traci L. Bricker, John H. Russell, Jonathan M. Green

Open Access Publications

No abstract provided.

Cell Cycle Checkpoint Defects Contribute To Genomic Instability In Pten Deficient Cells Independent Of Dna Dsb Repair, Arun Gupta, Qin Yang, Raj K. Pandita, Clayton R. Hunt, Tao Xiang, Sandeep Misri, Sicong Zeng, Rakesh Kumar, Zhihui Feng, Simon N. Powell, Audesh Bhat, Tej K. Pandita, Et Al

Open Access Publications

No abstract provided.

Hypercholesterolemia Is Associated With Hyperactive Cardiac Mtorc1 And Mtorc2 Signaling, Hilary P. Glazer, Robert M. Osipov, Richard T. Clements, Frank W. Sellke, Cesario Bianchi

Open Access Publications

No abstract provided.

Role Of Alpha Synuclein In Noise Induced Hearing Loss, Melissa Mooney

Independent Studies and Capstones

The recent discovery of the contribution of alpha synuclein in the auditory system prompted further investigation of its functional role. Auditory brainstem response (ABR) and gap detection testing were completed on wild-type and transgenic M83 mice to assess the role of alpha synuclein in noise-induced hearing loss and central auditory function.