Digital Commons Network^™

Redescription Of The Frog Bladder Fluke Gorgoderina Attenuata From The Northern Leopard Frog, Rana Pipiens, Matthew G. Bolek, Scott D. Snyder, John J. Janovy Jr.

John J. Janovy, Jr. Publications

Morphological characters used to differentiate North American bladder flukes, Gorgoderina spp., are problematic and different authors use different morphological characteristics for distinguishing species. More importantly, no type specimens exist for four of the 12 North American species infecting anuran and caudatan hosts. A redescription of Gorgoderina attenuata (Stafford, 1902) Stafford, 1905 is based on new collections from 6 species of anurans from Arkansas, Nebraska, New York, and Wisconsin. Morphological comparisons between gravid G. attenuata recovered from bullfrogs and northern leopard frogs indicated statistically significant differences in 11 of 28 morphological characters examined. However, there was overlap among all of these …

Alternative Life Cycle Strategies And Colonization Of Young Anurans By Gorgoderina Attenuata In Nebraska, Matthew G. Bolek, Scott D. Snyder, John J. Janovy Jr.

John J. Janovy, Jr. Publications

Studies on life cycles and epizootiology of North American frog bladder flukes indicate that adult frogs become infected predominantly by ingesting tadpoles or other frogs that serve as second intermediate hosts for gorgoderid metacercariae. Other studies have indicated that newly metamorphosed frogs are rarely infected with these parasites because they are gape-limited predators that cannot feed on large intermediate hosts such as tadpoles and other frogs. We examined the role of potential intermediate hosts in the recruitment of the frog bladder fluke, Gorgoderina attenuata, to metamorphosed northern leopard frogs, Woodhouse’s toads, and bullfrogs from western Nebraska. We completed the …

Pattern Of Congenital Heart Disease In Southern Yemeni Children Referred For Echocardiography, Hussein K. Saleh

Saudi Medical Journal

OBJECTIVE: To study the distribution of age, gender, and the relative frequency of congenital heart defects at the time of the diagnosis in Southern Yemeni children. METHODS: This retrospective study focused on echocardiographic findings of 393 symptomatic children affected by congenital heart disease. It was conducted in the Echocardiography Department of a referral hospital for Aden city and surrounding governorates, Yemen, from January 2001 to December 2005. RESULTS: Out of 987 referred children, congenital heart defects were detected in 393 (39.8%); mean age was 3.45±4 years; of them, 48% males and 52% females. They were 85% non-cyanotic and 15% cyanotic. …

Robustostrongylus Aferensis Gen. Nov. Et Sp. Nov. (Nematoda: Trichostrongyloidea) In Kob (Kobus Kob) And Hartebeest (Alcelaphus Buselaphus Jacksoni) (Artiodactyla) From Sub-Saharan Africa, With Further Ruminations On The Ostertagiinae, Eric P. Hoberg, Arthur Abrams, Patricia A. Pilitt

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Abomasal nematodes (Ostertagiinae: Trichostrongyloidea), representing a previously unrecognized genus and species, were discovered in kob (Kobus kob) and kongoni (hartebeest) (Alcelaphus buselaphus jacksoni) from Uganda during surveys of ungulate parasites in the 1960s. Robustostrongylus aferensis gen. nov. et sp. nov. is characterized by a ventriculus-like, bilobed valve at the junction of the esophagus and intestine, a synlophe with unusually robust ridges, cervical papillae and excretory pore situated posterior to the mid-length of the esophagus, a unique body form and large diameter in males and females, a relatively anterior position for the vulva, and strongly convoluted and …

Daggerblade Grass Shrimp (Palaemonetes Pugio): A Reservoir Host For Yellow-Head Virus (Yhv), Hongwei Ma, Robin M. Overstreet, Jean A. Jovonovich

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Yellow-head virus (YHV) is a major pathogen in penaeid shrimps. We surveyed 13 crustacean species in eight families from two orders that are commonly found in the Mississippi coastal area and freshwater environments as potential reservoir or carrier hosts of YHV. Using semi-nested polymerase chain reaction (PCR) on relatively small sample sizes, we did not detect any natural infection. However, when the daggerblade grass shrimp, Palaemonetes pugio, and the blue crab, Callinectes sapidus, were exposed to YHV by injection and per os, YHV was detected in the tissue of P. pugio and in the hemolymph of C. sapidus …

A Mathematical Model Of Cutaneous Leishmaniasis, Karthik Bathena

Theses

A SIS model for Cutaneous Leishmaniasis is developed and analyzed. The model contains a human population of incidental hosts, along with animals that are the reservoir hosts and the sandfly vector. Reproductive rates for the persistence of the infection are derived from the model. Conditions for the existence of endemic and disease-free equilibrium are obtained. The stability analysis of the disease-free equilibrium is investigated and numerical simulations for the model are provided.

Prion Protein Glycosylation Is Not Required For Strain-Specific Neurotropism, Justin R. Piro, Brent T. Harris, Koren Nishina, Claudio Soto, Rodrigo Morales, Judy R. Rees, Surachai Supattapone

Dartmouth Scholarship

In this study, we tested the hypothesis that the glycosylation of the pathogenic isoform of the prion protein (PrP^Sc) might encode the selective neurotropism of prion strains. We prepared unglycosylated cellular prion protein (PrP^C) substrate molecules from normal mouse brain by treatment with PNGase F and used reconstituted serial protein cyclic misfolding amplification reactions to produce RML and 301C mouse prions containing unglycosylated PrP^Sc molecules. Both RML- and 301C-derived prions containing unglycosylated PrP^Sc molecules were infectious to wild-type mice, and neuropathological analysis showed that mice inoculated with these samples maintained strain-specific patterns of PrP …

Enhancing Accountability: Servsafe™ Impact Template Delivers, Renee Boyer, Matthew C. Benson, Heather H. Boyd, Mena Forrester, Nancy Franz, Karen Gehrt, Patsy Pelland, Kirsten Roan

Journal of Extension

Generating statewide impact data from Extension programs can be challenging. To streamline reporting, Extension specialists, with the help of county agents and administrators, generated a statewide impact statement for the ServSafe™ program in Virginia. This template includes knowledge gain, behavior change, and economic impact from participants generated from current standardized evaluation methods used by all Extension educators across the state. Providing this template for agents resulted in easier, more consistent yearly reporting for those agents administering the program.

Determinants Of Risky Sexual Behaviors Of Kenyan Immigrant Men In The Us And During Visits In Kenya, Japheth K. Kaluyu

Dissertations

Kenyan immigrant men originate from sub-Saharan Africa with the highest HIV prevalence in the world. The study hypotheses were: 1) Attitude towards condom use differs between Kenya and the US, 2) Condom use behavior with primary sex partners differ between Kenya and the US, 3) Condom use behavior with casual sex partners differ between Kenya and the US, 4) Sexual behaviors with casual partners differ between Kenya and the US, 5)Age affects risky sexual behaviors in the US, 6) Age affects risky sexual behaviors during visits in Kenya, 7) Income affects risky sexual behaviors in the US, 8) Income affects …

Commencement, Philadelphia (2009), Philadelphia College Of Osteopathic Medicine

Commencements

Philadelphia Campus D.O. Commencement program, 118th Class. Degrees include Doctorate in Osteopathic Medicine.

Impact Of Infection Control Activities On The Rate Of Needle Stick Injuries At A Tertiary Care Hospital Of Pakistan Over A Period Of Six Years: An Observational Study., Afia Zafar, Faiza Habib, Roshan Hadwani, Muslima Ejaz, Khurshid Khowaja, Rozina Khowaja, Seema Irfan

Department of Pathology and Laboratory Medicine

Background:Accidental exposure to blood and body fluids is frequent among health care workers. They are at high risk of nosocomial transmission of blood borne pathogens due to injuries caused by used sharps. We are reporting impact of surveillance and educational program on the rate of needle stick injuries among health care workers at a tertiary care hospital in Pakistan.

Methods:

At Aga Khan University Hospital sharp injuries are reported to infection control office. To reduce these incidents a quality improvement project was inducted in the year 2005. Health care workers were educated, surveillance data from 2002 to 2007 was …

Uropathogenic E. Coli Employ A Conserved Intracellular Infection Pathway That Can Be Inhibited By Novel Anti-Virulence Therapeutics, Corinne Cusumano

All Theses and Dissertations (ETDs)

Urinary tract infections: UTIs) affect 13 million women annually in the United States and are predominately caused by uropathogenic Escherichia coli: UPEC). In a murine cystitis model, UPEC utilize a multistep pathogenic pathway in which they invade and form intracellular bacterial communities: IBCs) within bladder facet cells. Type 1 pili expressing the adhesin, FimH, are necessary for UPEC binding and invasion of urothelial cells and formation of IBCs. UPEC ultimately disperse from the IBC, many with filamentous morphology, and infect other host urothelial cells. Using a panel of UPEC clinical isolates, this work evaluates the conservation of the IBC pathway …

Addressing Amphibian Decline Through The Amphibian Conservation Action Plan, Dante B. Fenolio

Open Access Dissertations

The amphibian decline phenomenon now involves in excess of a third of the roughly 6000 species of amphibians on the planet. The problems that drive the declines are diverse with no end in sight. The Amphibian Conservation Action Plan (ACAP) aims to stem amphibian decline through four recommended actions by researchers and conservation biologists: (1) Expand scientific understanding of amphibian declines and extinctions; (2) continue to document amphibian diversity and ecology and how they are changing; (3) develop and implement long-term conservation programs; (4) prepare emergency response actions for eminent crises. This Dissertation focused on two of those recommendations: expanding …

A Network-Aware Distributed Membership Protocol For Collaborative Defense, David Zage, Carl Livadas, Eve M. Schooler

Department of Computer Science Technical Reports

No abstract provided.

Spectator 2009-05-20, Editors Of The Spectator

The Spectator

No abstract provided.

Recombinant Aav Gene Therapy And Delivery, Nikisha Christine Carty

USF Tampa Graduate Theses and Dissertations

Alzheimer's disease (AD), first characterized in the early 20th century, is a common form of dementia which can occur as a result of genetic mutations in the genes encoding presenilin 1, presenilin 2, or amyloid precursor protein (APP). These genetic alterations can accelerate the pathological characteristics of AD, including the formation of extracellular neuritic plaques composed of amyloid beta peptides and the formation of intracellular neurofibrillary tangles consisting of hyperphosphorylated tau protein. Ultimately, AD results in gross neuron loss in the brain which is evidenced clinically as a progressive decline in mental capacity. A strong body of scientific evidence has …

An Exploratory Study Of Adherence To Prescribed Health Care Recommendations Among A Community Sample Of Drug Users And Non-Drug Users From Similar Neighborhoods In Miami-Dade County, Karen L. Pierre

Open Access Dissertations

This dissertation had three specific aims: to estimate the prevalence of adherence among drug users, to determine whether drug use was directly associated with adherence, and to assess whether factors drawn from the Behavioral Model of Health Care Utilization (BMHCU) are associated with adherence. The self-reported prevalence of adherence to prescribed health care recommendations in the past 12 months among the community sample of drug users and non-drug users from similar low-income areas in the study sample ranged from 53%-74%. Non-drug users consistently had higher rates of adherence than drug users, except for adherence to female health care recommendations, yet …

Central Florida Future, Vol. 41 No. 45, May 18, 2009

Central Florida Future

Tuition will increase 15 percent this fall; Tuition hike explained; Tipping protocol causes confusion at area eateries; Construction cramps space; Food service tipping; Research may lessen HIV risk.

Lessons From The River: Identifying Factors That Influence The Comprehension Of Genetics Research In A Yup'ik Eskimo Community, Kathleen Mcglone West

Biological Sciences

"The Center for Alaska Native Health Research (CANHR) follows a Community-Based Participatory Research (CBPR) approach to study genetic, nutritional, behavioral and cultural protective factors for obesity and Type 2 diabetes in Yup'ik Eskimo communities. As a multidisciplinary center, investigators have returned results of many of their research projects to participants and participating communities. However, traditionally, genetics research results are only returned to participants under specific conditions, which are not necessarily compatible with a CBPR approach. I ask how CANHR can improve its dissemination efforts, especially in the area of genetics research. I identify factors that influence how community members receive …

Direct To Consumer Drug Advertisements: A Dangerous Game Of Pitching Products To Parents, Lynne Graziano

Annual Conference Presentations, Papers, and Posters

The annual budget for drug advertising in the United States exceeds that for all undergraduate and postgraduate medical education and comes close to the entire budget of the National Institutes of Health. In 2008 drug advertisers spent $4.7 billion, down from a record $4.8 billion in 2006, but up from $2.6 billion in 2002. Since the relaxation of full disclosure rules for television advertising, the amount spent on direct-to-consumer advertisements (DTCA) has soared, leading to increased sales of certain pharmaceuticals, as advertisements are placed in magazines, newspapers, internet websites and on television. These prescription-drug ads prompt nearly one-third of Americans …

Hiv Policy: The Path Forward--A Joint Position Paper Of The Hiv Medicine Association Of The Infectious Diseases Society Of America And The American College Of Physicians., Christine Lubinski, Judith Aberg, Arlene D Bardeguez, Richard Elion, Patricia Emmanuel, Daniel Kuritzkes, Michael Saag, Kathleen E Squires, Andrea Weddle, Jennifer Rainey, M Renee Zerehi, J Fred Ralston, David A Fleming, David Bronson, Molly Cooke, Charles Cutler, Yul Ejnes, Robert Gluckman, Mark Liebow, Kenneth Musana, Mark E Mayer, Mark W Purtle, P Preston Reynolds, Lavanya Viswanathan, Kevin B Weiss, Baligh Yehia

Department of Medicine Faculty Papers

Executive Summary

The American College of Physicians (ACP) and the Infectious Diseases Society of America (IDSA) have jointly published 3 policy statements on AIDS, the first in 1986 [1], the second in 1988 [2], and the third in 1994 [3]. In 2001, the IDSA created the HIV Medicine Association (HIVMA), and this updated policy paper is a collaboration between the ACP and the HIVMA of the IDSA. Since the last statement, many new developments call for the need to reexamine and update our policies relating to HIV infection. First, there have been major advances …

Genome Degradation In Brucella Ovis Corresponds With Narrowing Of Its Host Range And Tissue Tropism, Renee M. Tsolis, Rekha Seshadri, Renato L. Santos, Felix J. Sangari, Juan M. García Lobo, Maarten F. De Jong, Qinghu Ren, Garry Myers, Lauren M. Brinkac, William C. Nelson, Robert T. Deboy, Samuel Angiuoli, Hoda Khouri, George Dimitrov, Jeffrey R. Robinson, Stephanie Mulligan, Richard L. Walker, Philip E. Elzer, Karl A. Hassan, Ian T. Paulsen

Faculty Publications

Brucella ovis is a veterinary pathogen associated with epididymitis in sheep. Despite its genetic similarity to the zoonotic pathogens B. abortus, B. melitensis and B. suis, B. ovis does not cause zoonotic disease. Genomic analysis of the type strain ATCC25840 revealed a high percentage of pseudogenes and increased numbers of transposable elements compared to the zoonotic Brucella species, suggesting that genome degradation has occurred concomitant with narrowing of the host range of B. ovis. The absence of genomic island 2, encoding functions required for lipopolysaccharide biosynthesis, as well as inactivation of genes encoding urease, nutrient uptake and utilization, and outer …

Synthesis And Evaluation Of Stimulatory Properties Of Glycolipids For Natural Killer T Cells, Xiangtian Long

Theses and Dissertations

Natural killer T cells (NKT cells) are a subset of T cells. They regulate a wide range of diseases including infection, tumor growth, and autoimmune diseases, through recognizing glycolipid antigens in the context of CD1d. An understanding of the scope of glycolipid antigens would facilitate use of this cell type in controlling immune responses. Till today, a lysosomal glycolipid, isoglobotrihexosylceramide (iGb3), is the only natural glycolipid that has been found to be recognized by both human and mouse NKT cells. To elucidate the molecular basis of this specific recognition, iGb3 variants were designed and prepared: i) replacement of the C26 …

A Case Study On Using The Via Christi Breastfeeding Assessment Tool In A Clinical Setting, Rouba Taha

Honors Scholar Theses

Aims- The goal of this study is to obtain a subjective point of view of the use, benefits, and shortcomings of the Via Christi breastfeeding Assessment Tool in a clinical setting.

Methods- This case study is based on a single yet detailed interview with a lactation consultant who has utilized the Via Christi Breastfeeding Tool in a clinical setting.

Findings- Advantages of the Via Christi Breastfeeding Assessment Tool include that the tool is practical and concrete, encompassing both a subjective dimension and the basic elements of breastfeeding. Shortcomings of the tool include its non-specificity in focus on the feeding technique …

Head And Neck Embryology: An Overview Of Development, Growth And Defect In The Human Fetus, Allison Baylis

Honors Scholar Theses

The purpose of this research is to explore the growth and formation of the head and neck from embryological development through puberty in order to understand how this knowledge is necessary for the development of dental and medical treatments and procedures. This is a necessary aspect of the medical and dental school curriculum at the University of Connecticut Health Center Schools of Medicine and Dental Medicine that needs to be incorporated into the current study of embryology for first-year students. Working with Dr. Christine Niekrash, D.M.D, this paper will cover the embryology and growth of the head, face and oral …

To Vaccinate, Or Not? Health Care Providers And The Hpv Controversy, Nicole Elizabeth Hanbury

Honors Scholar Theses

Gardasil® – the vaccine was first thought to be a medical breakthrough in the fight against cancer, but it quickly became plagued with controversy. Despite wide media coverage, little attention has been paid to today’s health care professionals who are ultimately responsible for prescribing the vaccine, and who may be the most knowledgeable about it. The present study seeks to expand on previous literature by investigating health care providers’ current beliefs and practices with the human papillomavirus (HPV) immunization. It is essential that more recent research be performed in order to encompass current views of the vaccine, post FDA-approval.

Data …

Characterizing The Role Of Phaeobacter In The Mortality Of The Squid, Euprymna Scolopes, Brian Shawn Wong Won

Honors Scholar Theses

The subject of our study is the Hawaiian bobtail squid, Euprymna scolopes, which is known for its model symbiotic relationship with the bioluminescent bacterium, Vibrio fischeri. The interactions between E. scolopes and V. fischeri provide an exemplary model of the biochemical and molecular dynamics of symbiosis since both members can be cultivated separately and V. fischeri can be genetically modified 1. However, in a laboratory setting, the mortality of embryonic E. scolopes can be a recurrent problem. In many of these fatalities, the egg cases display a pink-hued biofilm, and rosy pigmentation has also been noted in the deaths of …

Differences In Resting And Exercising Pulmonary Function Among Sedentary, Resistance-Trained And Aerobically-Trained, Early Symptomatic, Hiv-1 Seropositive Men, Craig C. Talluto

Open Access Dissertations

The human immunodeficiency virus (HIV)-1 can compromise pulmonary function at all stages of the disease. The present study examined whether there were differences in resting and exercising pulmonary function among sedentary, resistance-trained and aerobically-trained, early symptomatic, HIV-1+ men. Forty five subjects, 15 per group, were enrolled. An analysis of variance (ANOVA) showed differences in demographics for age [F (2, 42) = 5.14, p

A Human Security Population-Based Approach To Achieve Equity, Solidarity And Gender Sensitivity For The Population Living In Southwestern Bateyes Of The Dominican Republic, Eddy Nelson Perez

Open Access Dissertations

The present study was designed to contribute to the application of human security principles in vulnerable populations, using the Bateyes (sugar mill camps) from the Dominican Republic (DR) as a case study. Following the Robin Hood principle of using resources allocated for the identification and treatment of human immunodeficiency virus (HIV) as a base from which to build infrastructure for other health and human security needs, this project sought to reduce inequalities and promote equal rights in a vulnerable population living in isolated rural areas of the DR. The impact of a human security model versus non-intervention (standard of care) …

The Relationship Between Nurse To Population Ratio And State Health Ranking, Jeri Bigbee

Nursing Faculty Publications and Presentations

Objective: To evaluate the relationship between nurse to population ratio and population health, as indicated by state health ranking.

Design: Secondary analysis correlational design.

Sample: The sample consisted of all fifty states in the U.S.

Measurements: Data sources included the United Health Foundation’s 2006 state health rankings, the 2004 National Sample Survey for Registered Nurses, and the U.S. Health Workforce Profile from the New York Center for Health Workforce Studies.

Results: Significant relationships between nurse to population ratio and state health ranking (rho = -.446, p =.001) and 11 of the 18 components of the overall ranking (motor vehicle death …