Digital Commons Network^™

Ada News - 10/19/2009, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Group I Introns And Inteins: Disparate Origins But Convergent Parasitic Strategies, Rahul Raghavan, Michael F. Minnick

Biological Sciences Faculty Publications

No abstract provided.

The International Response To Climate Change: An Agenda For Global Health, Lindsay F. Wiley, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

As the international community negotiates a successor to the Kyoto Protocol of the United Nations Framework Convention on Climate Change (UNFCCC), there is new reason to hope that meaningful action might be taken to prevent devastating climate change. Even the more ambitious mitigation targets currently under negotiation, however, will not be sufficient to avoid a profound effect on the public's health in coming decades, with the world's poorest, most vulnerable populations bearing the disproportionate burden. The influence of historic and current emissions will be so substantial that it is imperative to reduce global emissions while at the same time preparing …

Heritable Factors Play A Major Role In Determining Host Responses To Wuchereria Bancrofti Infection In An Isolated South Pacific Island Population, Karen T. Cuenco, Eric A. Ottesen, Steven A. Williams, Thomas B. Nutman, Cathy Steel

Biological Sciences: Faculty Publications

Background. It is increasingly recognized that host genetic factors may play an important role in determining the outcome of filarial infections. To test this hypothesis in bancroftian lymphatic filariasis, pedigree data were collected twice during an 18-year period from an isolated Polynesian population living on a Pacific island where lymphatic filariasis is endemic. Methods. Using variance-component analysis, we examined the contribution of shared genetic and environmental effects on host clinical and immune responses to filarial infection, along with potential confounding determinants. Results. Sex was found to have a negligible influence on heritability estimates, but shared-household effects accounted for up to …

Washington University Record, October 15, 2009

Washington University Record

No abstract provided.

Healthy Planet, Healthy People: Integrating Global Health Into The International Response To Climate Change, Lindsay F. Wiley

Georgetown Law Faculty Publications and Other Works

The potentially groundbreaking negotiations currently underway on the international response to climate change and national implementation of commitments under the United Nations Framework Convention on Climate Change (UNFCCC) include a number of hotly contested issues: (1) what degree of climate change is acceptable as a basis for emissions targets, (2) to what extent and in what ways climate change mitigation should incorporate emissions reductions or increased sinks for developing countries, (3) whether the legal regime governing mitigation can take advantage of the huge mitigation potential of changed practices in the land use and agricultural sectors, (4) how adaptation should be …

Targeting Of Long Chain Triacylglycerol Hydrolase Gene For Tuberculosis Treatment, Pappachan Kolattukudy, Jaiyanth Daniel, Chirajyoti Deb

UCF Patents

Tuberculosis, caused by the organism Mycobacterium tuberculosis, is one of the major public health threats in the world. The emergence of multidrug resistant strains poses serious threats to the control of this disease due to the complex nature of second-line drug treatment. Upon infection, the bacterium goes through an initial replication phase after which it enters a nonreplicative, drug-resistant state of dormancy. The bacterium is able to survive in this dormant state for decades until the hosts immune system is weakened when it reactivates and causes the infectious disease.

Monitoring Early Season Mosquito And Bird Populations: Implications For West Nile Virus In Lancaster County, Nebraska, Jason Thiele, Trevor Hefley, Lindsay Beck-Johnson, Emily Matthews

RURALS: Review of Undergraduate Research in Agricultural and Life Sciences

West Nile virus (WNV) surveillance efforts in Nebraska focus on the late summer and early fall months. We studied mosquito and bird populations in Lancaster County, Nebraska to evaluate the potential for WNV transmission in the late spring and early summer, prior to occurrences of human WNV infections. Culex tarsalis is the most important vector of WNV in Nebraska and was the focal species for the study. Mosquitoes were trapped at six locations representing three habitat types from May 14 to July 11, 2007. The C. tarsalis population, as estimated by the number of individuals caught in the traps each …

Protection Against Mucosal Shiv Challenge By Peptide And Helper-Dependent Adenovirus Vaccines, Eric A. Weaver, Pramod N. Nehete, Bharti P. Nehete, Stephanie J. Buchl, Donna Palmer, David C. Montefiori, Philip Ng, K. Jagannadha Sastry, Michael A. Barry

Nebraska Center for Virology: Faculty Publications

Groups of rhesus macaques that had previously been immunized with HIV-1 envelope (env) peptides and first generation adenovirus serotype 5 (FG-Ad5) vaccines expressing the same peptides were immunized intramuscularly three times with helperdependent adenovirus (HD-Ad) vaccines expressing only the HIV-1 envelope from JRFL. No gag, pol, or other SHIV genes were used for vaccination. One group of the FG-Ad5- immune animals was immunized three times with HD-Ad5 expressing env. One group was immunized by serotype-switching with HD-Ad6, HD-Ad1, and HD-Ad2 expressing env. Previous work demonstrated that serum antibody levels against env were significantly higher in the serotype-switched group than in …

Sbs General Campus Announcement 2009-10-09, Darren Johnson

Southampton Announcements and News

No abstract provided.

Washington University Record, October 8, 2009

Washington University Record

No abstract provided.

Development: Creating Sustainable Justice, Paul Farmer

Joan B. Kroc Distinguished Lecture Series

Table of Contents:

Joan B. Kroc Institute for Peace & Justice--p.4.
Joan B. Kroc Distinguished Lecture Series--p.6.
Biography--p.10.
Interview--p.12.
Welcome and Introduction--p.28.
Lecture--p.33.
Questions and Answers--p.57.
Related Resources--p.75.
About the University--p.76.

The Winonan, Winona State University

The Winonan - 2000s

No abstract provided.

The Colby Echo (2009-10-07), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

H1n1 Nasal Spray Vaccine Goes To Students In Um Residence Halls, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Utility Of Repeat Screening For Asymptomatic Bacteriuria In Pregnancy, Sara Whetstone

Yale Medicine Thesis Digital Library

UTILITY OF REPEAT SCREENING FOR ASYMPTOMATIC BACTERIURIA IN PREGNANCY Sara Whetstone, Stephen Thung, and Jessica Illuzzi. Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, School of Medicine, New Haven, CT. Asymptomatic bacteriuria (ASB) during pregnancy is associated with an increased risk of developing pyelonephritis. The objectives of our study were to determine the incidence of ASB throughout the first two trimesters of pregnancy and to compare the cost effectiveness of performing repeat screening with a single screening strategy for ASB to prevent pyelonephritis. In this prospective cohort study, 206 pregnant women at an urban academic obstetric clinic provided urine …

Current, October 05, 2009, University Of Missouri-St. Louis

Current (2000s)

No abstract provided.

Reporter - October 2nd 2009, Rit Reporter Staff

University Publications

No abstract provided.

Uconn School Of Medicine Dean's Newsletter, Fall 2009, Cato T. Laurencin

Annual Reports - Education

Welcome to the first issue of our new publication. Designed to be a quick and easy read, our goal is to convey the energy and passion found throughout the dynamic University of Connecticut School of Medicine.

I became the seventh dean of the UConn School of Medicine and vice president for Health Affairs at the UConn Health Center just a year ago. I joined the UConn community from the University of Virginia, where I served as the Lillian T. Pratt Distinguished Professor and chair of the Department of Orthopaedic Surgery. Since my arrival, I have been continually impressed with the …

Animal-Assisted Therapy As A Pain Relief Intervention For Children, Carie Braun, T. Stangler, J. Narveson, S. Pettingel

Nursing Faculty Publications

Animal-assisted therapy (AAT) is a healing modality involving a patient, an animal therapist, and handler with a goal of achieving a specified therapeutic outcome. Despite the myriad of studies documenting the benefits of AAT, no studies have yet determined the impact of animals on alleviation of pain in children. Therefore, a quasi-experimental intervention design was used to capture the change in pain and vital signs with (n = 18) or without (n = 39) AAT in children ages 3–17 in one acute care pediatric setting. The AAT intervention group experienced a significant reduction in pain level compared to …

Checkup, Lehigh Valley Health Network

Checkup

No abstract provided.

How To Build A Health Clinic: Disease Burden, Health Seeking Behavior And Clinic Structures In The Kibera Slums, Samuel Mcgowan

Independent Study Project (ISP) Collection

This study seeks to determine a model for a health clinic to be run by the Kibera School for Girls in the Katwekera village of Nairobi’s Kibera slums. The study examines the disease burden of the school’s initial target population, the health-seeking behavior of the community, and current clinic structures in Kibera. Using these methodological tactics, the study suggests the Kibera School for Girls should start a small, locally-run clinic that offers basic primary health care to a target population of about 5,000 Kibera residents.

The Statesman, V. 53, I. 08, Stony Brook University

Stony Brook Statesman-Sucolian

v. 53, i. 08

Assembly Of Arenavirus Envelope Glycoprotein Gpc In Detergent-Soluble Membrane Microdomains, Sudhakar S. Agnihothram, Brooke Dancho, Kenneth W. Grant, Mark L. Grimes, Douglas S. Lyles, Jack H. Nunberg

Biomedical and Pharmaceutical Sciences Faculty Publications

The family Arenaviridae includes a number of highly pathogenic viruses that are responsible for acute hemorrhagic fevers in humans. Genetic diversity among arenavirus species in their respective rodent hosts supports the continued emergence of new pathogens. In the absence of available vaccines or therapeutic agents, the hemorrhagic fever arenaviruses remain a serious public health and biodefense concern. Arenaviruses are enveloped virions that assemble and bud from the plasma membrane. In this study, we have characterized the microdomain organization of the virus envelope glycoprotein (GPC) on the cell surface by using immunogold electron microscopy. We find that Junin virus (JUNV) GPC …

Ectopic T-Bet Expression Licenses Dendritic Cells For Il-12-Independent Priming Of Type 1 T Cells In Vitro, Michael Lipscomb

Department of Biology Faculty Publications

T-bet (TBX21) is a transcription factor required for the optimal development of type 1 immune responses. Although initially characterized for its intrinsic role in T cell functional polarization, endogenous T-bet may also be critical to the licensing of type 1-biasing APCs. Here, we investigated whether human dendritic cells (DC) genetically engineered to express high levels of T-bet (i.e., DC.Tbet) promote superior type 1 T cell responses in vitro. We observed that DC.Tbet were selective activators of type 1 effector T cells developed from the naive pool of responder cells, whereas DC.Tbet and control DC promoted type 1 responses equitably from …

Countering Weapons Of Mass Destruction: Looking Back, Looking Ahead, Paul I. Bernstein, John P. Caves Jr., W. Seth Carus

WMD Occasional Papers

Nearly 20 years have passed since the United States began worrying in earnest about the risks of regional weapons of mass destruction (WMD) proliferation. In the run-up to Operation Desert Storm in 1990, the Department of Defense (DOD) had no systematic understanding of or approach to prosecuting a regional war against an adversary armed with and prepared to use nuclear, biological, or chemical weapons. The improvisational efforts to prepare for possible Iraqi WMD use gave way after the war to a concerted effort during the Bill Clinton administration to prepare the Armed Forces to confront WMD-armed regional adversaries, while working …

Controlling The Dengue Mosquito (Aedes Aegypti): Assessment Of The Effects Of Metofluthrin, A Novel Vapor-Active Pyrethroid, On Mosquito Behavior In A Modeled Domestic Setting., Randy Kring

Independent Study Project (ISP) Collection

Dengue fever is a potentially life-threatening illness that is endemic in over 100 countries and threatens approximately half of the world’s population. The dengue virus is transmitted between humans by a mosquito vector, principally the dengue mosquito, Aedes aegypti. This mosquito prefers to live and feed in and around people’s homes. As a result, preventing mosquito bites within a domestic setting is essential to controlling the dengue virus. Although several methods of bite prevention are currently available to the public, most of these methods only provide short-term protection from the dengue mosquito. In contrast, a recently developed synthetic pyrethroid called …

Global Fund To Fight Aids, Tuberculosis And Malaria: A New Legal And Conceptual Framework For Providing International Development Aid, Anna Triponel

North Carolina Journal of International Law

No abstract provided.

Deep Ecology And End-Of-Life Care, Paul Carrick

Philosophy Faculty Publications

Physicians and nurses caring for terminally ill patients are expected to center their moral concerns almost exclusively on the needs and welfare of the dying patient and the patients family. But what about the relationship of traditional medical ethics to the emerging new theories of environmental ethics, like deep ecology? As we glide into the twenty-first century, can anyone seriously doubt that the mounting global concerns of environmental ethics will eventually influence the ethics of medicine too?

For example, suppose physicians were to integrate the core values of an ecocentric environmental ethic like deep ecology into contemporary North American norms …

The Production Of Antibody By Invading B Cells Is Required For The Clearance Of Rabies Virus From The Central Nervous System., D Craig Hooper, Timothy W Phares, Marzena J Fabis, Anirban Roy

Department of Cancer Biology Faculty Papers

BACKGROUND: The pathogenesis of rabies is associated with the inability to deliver immune effectors across the blood-brain barrier and to clear virulent rabies virus from CNS tissues. However, the mechanisms that facilitate immune effector entry into CNS tissues are induced by infection with attenuated rabies virus.

METHODOLOGY/PRINCIPAL FINDINGS: Infection of normal mice with attenuated rabies virus but not immunization with killed virus can promote the clearance of pathogenic rabies virus from the CNS. T cell activity in B cell-deficient mice can control the replication of attenuated virus in the CNS, but viral mRNA persists. Low levels of passively administered rabies …