Digital Commons Network^™

Genetic Variation In Mother-Child Acute Seroconverter Pairs From Zambia, Federico G. Hoffmann, Xiang He, John T. West, Philippe Lemey, Chipepo Kankasa, Charles Wood

School of Biological Sciences: Faculty Publications

Objective: To characterize the envelope (Env) glycoprotein of HIV-1 in mother-infant pairs (MIP) that underwent near simultaneous or acute-phase seroconversion, we examined the Env sequence of the transmitted viruses and compare viral evolution within the pair.

Design: Three MIP from a Zambian cohort that seroconverted at the same sampling time were identified and followed longitudinally.

Methods: The V1-V5 region of the HIV-1 Env gene was sequenced for each sample collected. Phylogenetic and population genetics analyses were carried out to subtype the viruses, estimate relationships among viral genotypes, and compare molecular evolution between the viral populations.

Results: Genetic analyses demonstrated a …

Disruption Of C-Jun Reduces Cellular Migration And Invasion Through Inhibition Of C-Src And Hyperactivation Of Rock Ii Kinase., Xuanmao Jiao, Sanjay Katiyar, Manran Liu, Susette C Mueller, Michael P. Lisanti, Anping Li, Timothy G Pestell, Kongming Wu, Xiaoming Ju, Zhiping Li, Erwin F Wagner, Tatsuo Takeya, Chenguang Wang, Richard G Pestell

Kimmel Cancer Center Faculty Papers

The spread of metastatic tumors to different organs is associated with poor prognosis. The metastatic process requires migration and cellular invasion. The protooncogene c-jun encodes the founding member of the activator protein-1 family and is required for cellular proliferation and DNA synthesis in response to oncogenic signals and plays an essential role in chemical carcinogenesis. The role of c-Jun in cellular invasion remains to be defined. Genetic deletion of c-Jun in transgenic mice is embryonic lethal; therefore, transgenic mice encoding a c-Jun gene flanked by LoxP sites (c-jun(f/f)) were used. c-jun gene deletion reduced c-Src expression, hyperactivated ROCK II signaling, …

Measuring Bite Force In Small Mammals With A Piezo-Resistive Sensor, Patricia W. Freeman, Cliff A. Lemen

University of Nebraska State Museum: Mammalogy Papers

We tested the use of piezo-resistive force sensors to measure bite force in small mammals. These force sensors are thin (less than 1 mm) and can be used to measure forces up to 4,500 N. A battery-operated unit, ideal for field research, can be built easily and inexpensively. We tested this sensor in the laboratory and in the field on a variety of small mammals. Although our results indicate that the sensor is somewhat less accurate (coefficient of variation = 4%) than a conventional load cell, the small size and ease of use of the piezo-resistive detector is highly desirable. …

Gene Expression Profiling In Women With Breast Cancer In A Saudi Population, Suad M. Bin-Amer, Zakia Maqbool, Maimoona S. Nirmal, Amal T. Qattan, Syed S Hussain, Hatim A. Jeprel, Asma M. Tulbah, Osama A. Malik, Taher A. Al-Tweigeri

Saudi Medical Journal

OBJECTIVE: To generate consensus gene expression profiles of invasive breast tumors from a small cohort of Saudi females, and to explore the possibility that they may be broadly conserved between Caucasian and Middle Eastern populations. METHODS: This study was performed at King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia, from January 2005 to January 2007. Gene expression profiles were generated from 38 invasive breast tumors, and 8 tumor adjacent tissues TATs using BD Atlas cDNA expression arrays containing 1176 genes. Results were confirmed by reverse transcriptase polymerase chain reaction, and analyzed by 2-dimensional unsupervised hierarchical clustering. …

Campylobacter Jejuni Induces Diverse Kinetics And Profiles Of Cytokine Genes In Int-407 Cells, Ahlam I. Al-Amri, Giuseppe A. Botta, Khaled S. Tabbara, Abdelrahman Y. Ismaeel, Ali E. Al-Mahmeed, Ahmed Y. Qareeballa, Moiz O. Bakhiet

Saudi Medical Journal

OBJECTIVE: To examine the kinetic ability of embryonic human epithelial INT-407 cells to express messenger ribonucleic acid mRNA for various cytokines and chemokines in response to Campylobacter jejuni C. jejuni stimulation. METHODS: In an experimental single-blind study, cultured embryonic human epithelial INT-407 cells were treated with different concentrations of viable C. jejuni, its sonicated, and filtered supernatant. A modified non-radioactive in situ hybridization using probe cocktails was used to measure mRNA levels for the pro-inflammatory cytokines interleukin IL-1beta, IL-6, interferon-gamma IFN-gamma, tumour necrosis factor TNF-alpha, transforming growth factor TGF-beta1, and IL-8, and the anti-inflammatory cytokines, IL-4 and IL-10. The study …

Usefulness Of Procalcitonin And Some Inflammatory Parameters In Septic Patients, Wael R. Tasabehji, Faizah A. Al-Quobaili, Nizar A. Al-Daher

Saudi Medical Journal

OBJECTIVE: To evaluate the efficacy of procalcitonin PCT to identify critically ill patients with sepsis in comparison with leukocyte count, body temperature, C-reactive protein CRP, erythrocyte sedimentation rate ESR, and interleukin-6 IL-6. METHODS: We performed our prospective observational study in 75 patients admitted with acute systemic inflammatory response and suspected infection. The final diagnosis was systemic inflammatory response syndrome SIRS in 38 patients, sepsis in 22, severe sepsis in 10, and suspected viral sepsis in 5. Blood samples were taken on the first day of hospitalization in Al Mwasaa Hospital, Damascus, Syrian Arab Republic, from July 2006 to January 2007. …

Apoptosis Is The Most Efficient Death-Pathway In Tumor Cells After Topoisomerase Ii Inhibition, Raafat A. El-Awady, Mahmoud M. Ali, Ekram M. Saleh, Fayek M. Ghaleb

Saudi Medical Journal

OBJECTIVE: To compare the efficiency of apoptosis and other modes of cell death in killing tumor cells after the induction of DNA damage by topoisomerase inhibitors like etoposide. METHODS: This study was carried out in the Tumor Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt, from September 2005 to August 2007. The breast cancer MCF7, the cervix carcinoma, human cervical adenocarcinoma Hela, and the brain tumor U251 cell lines were exposed to etoposide. Apoptosis was detected using the flow cytometry and the DNA ladder formation methods. Cell viability was determined by a colorimetric assay, and the residual DNA double-strand …

Circulatory Neutrophil Chemokines In Statin-Treated Diabetic Patients, Assim A. Alfadda, Mohammed A. Alzoghaibi

Saudi Medical Journal

OBJECTIVE: To assess the effect of statins on the circulatory levels of neutrophil chemokines, namely, granulocyte chemotactic protein-2 GCP-2, growth regulated oncogene-alpha GRO-a and epithelial-cell-derived neutrophil-activating peptide-78 ENA-78 in patients with diabetes. METHODS: We studied 91 diabetic patients 46 were statin-treated and 45 were not and 28 healthy subjects. We measured the levels of GCP-2, GRO-a, and ENA-78 in the serum for the 3 groups using an enzyme linked immunosorbent assay. This cross-sectional study was conducted at King Khalid University Hospital KKUH, Riyadh, Kingdom of Saudi Arabia, from January 2006 to July 2007. RESULTS: Circulating levels of GCP-2, ENA-78, and …

Microbial Yield In Febrile Sickle Cell Disease Patients With Acute Painful Episode From A University Hospital In The Sultanate Of Oman, Asem A. Alghzaly, Salam S. Alkindi, Anil V. Pathare

Saudi Medical Journal

No abstract provided.

A Hole Of Human Immunodeficiency Virus Hiv/Aids And Hunger In Rural Nigerian Communities, Ogboi S. Johnbull

Saudi Medical Journal

No abstract provided.

Emergence Of Multi And Pan-Drug Resistance Acinetobacter Baumannii Carrying Blaoxa-Type-Carbapenemase Genes Among Burn Patients In Tehran, Iran, Morrovat Taherikalani, Gelavizh Etemadi, Keramat N. Geliani, Bahram Fatollahzadeh, Setareh Soroush, Mohammad M. Feizabadi

Saudi Medical Journal

No abstract provided.

Severe Personality Disorders, Abdulrahman Al-Asmari

Saudi Medical Journal

No abstract provided.

New Genus And Species Of Aporocotylidae (Digenea) From A Basal Actinopterygian, The American Paddlefish, Polyodon Spathula, (Acipenseriformes: Polyodontidae) From The Mississippi Delta, Stephen A. Bullard, Scott D. Snyder, Kirsten Jensen, Robin M. Overstreet

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Acipensericola petersoni n. gen., n. sp. (Digenea: Aporocotylidae) infects the heart of the American paddlefish Polyodon spathula (Walbaum, 1792) in the Mississippi Delta. It has robust, spike-like body spines arranged in ventrolateral transverse rows; a bowl-shaped anterior sucker centered on the mouth and having minute spines on the inner anteroventral surface only; a pharynx; an inverse U-shaped ceca extending to near the posterior body end; intercecal testes comprising a pre-ovarian testicular column plus a single testis posteriorly; an extensively lobed ovary located medially and immediately posterior to the testicular column; a spherical ootype that is intercecal and post-ovarian; a Laurer’s …

California Drought, An Update April 2008, Baryohay Davidoff, Fawzi Karajeh, Dean Reynolds, Eric Senter, John Woodling

United States Geological Survey: Staff Publications

TABLE OF CONTENTS

CHAPTER 1. RECENT HYDROLOGIC CONDITIONS AND IMPACTS

Introduction....................................................... 1

Water Year 2007 .................................................. 1

Drought in the Colorado River Basin ..................................................... 5

Drought and Dry Conditions in the Early 2000s .................................... 7

The 2001 Klamath Basin Drought Emergency ............................... 11

CHAPTER 2. PROGRAMMATIC AND INSTITUTIONAL UPDATES

The San Francisco Bay-Sacramento/San Joaquin River Delta.................................................................. 15

The Colorado River .................................................................... 16

State Financial Assistance to Local Agencies.................................... 17

Urban Water Management Planning ................................................... 20

Water Transfers .............................................................................. 20

Small Water Systems and Drought Preparedness ................................. 21

Too Little, Too Late: The Current Generation Of College Women And Sexual Health Education, Nicole C. Schumaker

Masters Theses

This research was conceived when I acknowledged the ways in which women of my generation have been educated about their bodies and about their sexuality. In a review of the literature on adolescent female sexuality, there is substantial evidence to suggest that in regards to early female sex education, adolescent sexuality is linked with danger, victimization, and passivity. Accordingly, it is asserted that these understandings of female sexuality disallow young girls to see themselves as initiators and decision-makers thus compromising their development of sexual subjectivity and responsibility in adulthood.

Data for this project were collected through ten semi-structured interviews with …

Prospects And Limitations For Ecocultural Tourism In The City: Developing An Urban Heritage Water Trail On The Portage Creek, Eric Mark Kerney

Masters Theses

The decline in Michigan's economy and rapid loss of manufacturing jobs has forced communications to look towards new possibilities. The state's abundant water resources have potential to enhance regional economies and improve the quality of life. The Michigan Heritage Water Trails Program was initiated in 2002 by Michigan Public Act 454 in response to a lack of established routes in the state. The Portage Creek is located within the Kalamazoo River Watershed, which is being explored as a pilot project for a connected system of regional water trails. The study area of the Portage Creek is located entirely within the …

Habitat Suitability Modeling For Lake Huron Tansy In Michigan, Cathryn Elizabeth Whately

Masters Theses

Little scientific research has been published that addresses the habitat requirement of the Lake Huron tansy, a Michigan threatened species. Adequate protection of the tansy, location of new populations, and identification of potential restoration sites all depend on defining suitable habitat. Mahalanobis distance and partitioned Mahalanobis distance were combined with geographic information systems (GIS) to spatially model habitat suitability for Lake Huron tansy in Michigan. Several models were created for shoreline areas within the 14 counties in northern Michigan where the tansy is found. Results suggested elevation, distance to shore, slope, direction to shore and aspect were important variables for …

Using Composite Sampling Techniques To Monitor Bathing Beach Water Quality In Kalamazoo County, Michigan, Jeffrey David Reicherts

Masters Theses

The Kalamazoo County Health and Community Services Department conducts water quality monitoring at public bathing beaches to determine public health risks and compliance with Michigan water quality standards. These standards require local health departments to collect and analyze a minimum of three water samples during each sampling event. Water samples are analyzed for Escherichia coli (E. coli) bacteria, an organism that indicates the presence of fecal contamination. During the 2007 sampling season, nine bathing beaches were monitored once each week. Three individual point samples (n = 486) and a composite sample (n = 144) were analyzed for each sampling …

Poster Abstracts, Sigma Xi Research Day 2008

Sigma Xi Student Research Day

No abstract provided.

K-Sketch: A 'Kinetic' Sketch Pad For Novice Animators, Richard C. Davis, Brien Colwell, James A. Landay

Research Collection School Of Computing and Information Systems

Because most animation tools are complex and timeconsuming to learn and use, most animations today are created by experts. To help novices create a wide range of animations quickly, we have developed a general-purpos informal, 2D animation sketching system called K-Sketch. Field studies investigating the needs of animatorsnd would-be animators helped us collect a library of usage scenarios for our tool. A novel optimization technique enabled us to design an interface that is simultaneously fast, simple, and powerful. The result is a pen-based system that relies on users’ intuitive sense of space and time while still supporting a wide range …

Limnological Assistance For The Lake Mead National Recreation Area In Meeting The Challenge Of The Water 2025 Initiative: Quarterly Progress Report, Period Ending: April 1, 2008, Margaret N. Rees

Limnological Studies

Hiring: A decision is anticipated in the upcoming weeks regarding the hiring of a limnologist. Two candidates were selected from among three qualified applicants for telephone interviews; they were subsequently interviewed in-person.

Project 1: Review of the draft Boulder Basin Adaptive Management Plan is on-going. Meetings of the Systems Conveyance and Operations Program (SCOP) Technical Advisory Teams were attended.

Project 2: Development of a white paper expressing the joint needs of the entities involved in Water 2025 projects is on-going; scientific review of data and reports related to bacteria in high-use areas of Lake Mead is underway.

Project 3: Discussions …

Fire Effects On Gambel Oak In Southwestern Ponderosa Pine-Oak Forests, Scott R. Abella, Peter Z. Fule

Public Policy and Leadership Faculty Research

Gambel oak (Quercus gambelii) is ecologically and aesthetically valuable in southwestern ponderosa pine (Pinus ponderosa) forests. Fire effects on Gambel oak are important because fire may be used in pine-oak forests to manage oak directly or to accomplish other management objectives. We used published literature to: (1) ascertain historical fire regimes in pine-oak forests, (2) discern prescribed burning effects on Gambel oak survival and diameter growth, and (3) provide suggestions for using fire to manage oak. Frequent fire is part of Gambel oak’s historical environment, as historical fire return intervals often averaged less than 10 years in pine-oak forests. More …

Plant Community Response To Fire: A Chronosequence Study, Scott R. Abella, E. Cayenne Engel

Public Policy and Leadership Faculty Research

Fires are becoming more prevalent events across the landscape in the southwestern US. Over the next several decades the already arid southwest is predicted to become warmer and drier, with longer summers, and an increase of “extreme” weather events such as lightening inducing thunderstorms. While the “hotter and drier” forecast may indicate less abundant plant life, and thus less available biomass for fuel, exotic invasive plant species are becoming more dominant across the landscape with increases in human travel and commerce. Exotic species (particularly many of the invasive grasses) are adding fuel for the fires to burn when the annuals …

Connections Newsletter Spring 2008

Connections Newsletter

No abstract provided.

Inside Unlv, Shane Bevell, Mamie Peers, David Ashley, Diane Russell, Michelle Mouton, Grace Russell

Inside UNLV

No abstract provided.

Mojave Applied Ecology Notes Spring 2008, Lesley Defalco, E. Cayenne Engel, Scott R. Abella, Jessica E. Spencer, Jill E. Craig

Mojave Applied Ecology Notes

Post-fire restoration, fire chronosequence study, Joint Fire Science update, Weed Sentry program and DNWR surveys

Unlv Magazine, Tony Allen, Afsha Bawany, Barbara Cloud, Holly Ivy De Vore, Gian Galassi, Matthew K. Jacobsen, Michelle Mouton, Erin O'Donnell, Shane Bevell, Cate Weeks

UNLV Magazine

No abstract provided.

Substrates Preparation From Woody Tropical Waste Biomass For Biohydrogen Production, Dwi Susilaningsih, Theresia Umi Harwati, Khairul Anam, Yopi Yopi

Makara Journal of Technology

Substrates Preparation from Woody Tropical Waste Biomass for Biohydrogen Production. Addressing to the global warming problem, energy crisis and pollution, hydrogen production by micro-organisms using biotechnological approach should be considered, since it fulfils the recent society requirement to safely produce, renewable and environmental friendly energy. Hydrogen is one of the most promising green energy sources, because it is easily converted to electricity and cleanly combustible. There are three types of micro-organisms for hydrogen production, the first is cyanobacteria through the photosynthesis process, the second is anaerobic bacteria, which use organic substances as electron donor and energy and convert them to …

Biomass Production Chlorella Vulgaris Buitenzorg Using Series Of Bubble Column Photo Bioreactor With A Periodic Illumination, Anondho Wijanarko, Dianursanti Dianursanti, Muryanto Muryanto, Josia Simanjuntak, Praswasti Pembangun Dyah Kencana Wulan, Heri Hermansyah, Misri Gozan, Roekmijati Widaningroem Soemantojo

Makara Journal of Technology

Chlorella vulgaris Buitenzorg cultivation using three bubble column photo bioreactors arranged in series with a volume of 200 mL for 130 hours shows an increase of biomass production of Chlorella vulgaris Buitenzorg up to 1.20 times and a decrease of the ability of CO2 fixation compared to single reactor at a periodic sun illumination cycle. The operation conditions on cultivation are as following: T, 29.0oC; P,1 atm.; UG, 2.40 m/h; CO2, 10%; Benneck medium; and illumination source by Phillip Halogen Lamp 20W /12V/ 50Hz. Other research parameters such as microbial carbon dioxide transferred rate (qco2), CO2 transferred rate (CTR), energy …

Volume 01, Jessica Fields, Stephanie Neeley, Derek W. Hambright, Mary E. Lehman, Andrew R. Grzankowski, Zachary Johnson, Boone M. Prentice, Ashley M. Swandby, Victoria Morgan, Katie Williamson, Kristine G. Bender, Katelyn N. Romaine, D. Nicole Swann, Jessica Fox, Mike Mcateer, Alex Grabiec, Laura Nodtvedt, Nick Costa, Rachel Wolfe, Zack Dalton

Incite: The Journal of Undergraduate Scholarship

Introduction from Dean Dr. Charles Ross

Three Decades of Digging: Undergraduate Archeology at Longwood by Jessica Fields and Stephanie Neeley

Interactions of Allelopathy and Heat Stress in Plants by Derek W. Hambright and Mary E. Lehman

Inertial Electrostatic Confinement D-D Fusion Device: Construction and Simulation by Andrew R. Grzankowski

Shackled Nim by Zachary Johnson

Development of GC-MS and Chemometric Methods for the Analysis of Accelerants in Arson Cases by Boone M. Prentice

A Comparison of Image Analysis Methods in cDNA Microarrays by Ashley M. Swandby

Perceived Sexual Activity of Short and Long-Term Relationships by Victoria Morgan and Katie Williamson

Elderly …