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Articles 6631 - 6660 of 15511
Full-Text Articles in Entire DC Network
The Tiger Vol. 102 Issue 12 2008-04-18, Clemson University
The Tiger Vol. 102 Issue 12 2008-04-18, Clemson University
Tiger Newspapers
No abstract provided.
A Deletion Mutant Of Vitronectin Lacking The Somatomedin B Domain Exhibits Residual Plasminogen Activator Inhibitor-1-Binding Activity, Christine R. Schar, Grant E. Blouse, Kenneth H. Minor, Cynthia B. Peterson
A Deletion Mutant Of Vitronectin Lacking The Somatomedin B Domain Exhibits Residual Plasminogen Activator Inhibitor-1-Binding Activity, Christine R. Schar, Grant E. Blouse, Kenneth H. Minor, Cynthia B. Peterson
Faculty Publications
Vitronectin and plasminogen activator inhibitor-1 (PAI-1) are important physiological binding partners that work in concert to regulate cellular adhesion, migration, and fibrinolysis. The high affinity binding site for PAI-1 is located within the N-terminal somatomedin B domain of vitronectin; however, several studies have suggested a second PAI-1-binding site within vitronectin. To investigate this secondary site, a vitronectin mutant lacking the somatomedin B domain (rΔsBVN) was engineered. The short deletion had no effect on heparin-binding, integrin-binding, or cellular adhesion. Binding to the urokinase receptor was completely abolished while PAI-1 binding was still observed, albeit with a lower affinity. Analytical ultra-centrifugation on …
Co2 Fixation Kinetics Of Halothiobacillus Neapolitanus Mutant Carboxysomes Lacking Carbonic Anhydrase Suggest The Shell Acts As A Diffusional Barrier For Co2, Zhicheng Dou, Sabine Heinhorst, Eric B. Williams, C. Daniel Murin, Jessup M. Shively, Gordon C. Cannon
Co2 Fixation Kinetics Of Halothiobacillus Neapolitanus Mutant Carboxysomes Lacking Carbonic Anhydrase Suggest The Shell Acts As A Diffusional Barrier For Co2, Zhicheng Dou, Sabine Heinhorst, Eric B. Williams, C. Daniel Murin, Jessup M. Shively, Gordon C. Cannon
Faculty Publications
The widely accepted models for the role of carboxysomes in the carbon-concentrating mechanism of autotrophic bacteria predict the carboxysomal carbonic anhydrase to be a crucial component. The enzyme is thought to dehydrate abundant cytosolic bicarbonate and provide ribulose 1.5-bisphosphate carboxylase/oxygenase (RubisCO) sequestered within the carboxysome with sufficiently high concentrations of its substrate, CO2, to permit its efficient fixation onto ribulose 1,5-bisphosphate. In this study, structure and function of carboxysomes purified from wild type Halothiobacillus neapolitanus and from a high CO2-requiring mutant that is devoid of carboxysomal carbonic anhydrase were compared. The kinetic constants for the carbon …
Characterization Of Histone Acetylation During Sv40 Transcription, Lata Balakrishnan
Characterization Of Histone Acetylation During Sv40 Transcription, Lata Balakrishnan
Theses and Dissertations
Compaction of DNA by histone proteins helps to package the DNA into the nucleus at the expense of acting as a bather to biological processes that require access to the DNA. Addition and removal of acetyl groups from the histone tails with the help of enzymes known as histone acetyltransferases (HATs) and histone deacetylases (HDACs) appear to play a critical role in maintaining the structure of chromosomes and the regulation of gene expression. In order to better understand the role of histone hyperacetylation in the regulation of gene expression I studied histone hyperacetylation in Simian Virus 40 (SV40) chromosomes during …
Toward A New Perspective In Literary Criticism: Transgenerational Psychoanalysis And Anasemic Procedures, Gustav Arnold
Toward A New Perspective In Literary Criticism: Transgenerational Psychoanalysis And Anasemic Procedures, Gustav Arnold
Theses and Dissertations
This dissertation—Toward a New Perspective in Literary Criticism: Transgenerational Psychoanalysis and Anasemic Procedures"—is a contribution to literary criticism. It offers a new perspective in psychoanalytical criticism on how characters in literary narratives can be interpreted. By examining key concepts in psychoanalysis, which have been used in the humanities for decades, the present inquiry draws on transgenerational psychology, as elaborated by German and French theorists, and anasemic interpretations generated by M. Torok and N. Abraham's psychoanalytical approach. Based on the assumption that a character's psychic life is determined by factors that cannot be confined to intrapsychic processes alone, the transgenerational perspective …
Altered Signaling By Fibronectin Fragments Creates A Potent Chondrolytic State, Lei Ding
Altered Signaling By Fibronectin Fragments Creates A Potent Chondrolytic State, Lei Ding
Theses and Dissertations
It has been shown that fibronectin fragments (Fn-fs) greatly augment cartilage proteoglycan (PG) depletion by up-regulating matrix metalloproteinases (MMPs) and catabolic cytokines. The activities of three different Fn-fs have been studied: an amino terminal 29-kDa which is most potent with a weak affinity to the α5β1, integrin, the receptor for native fibronetin (Fn); a 50-kDa gelatin-binding Fn-f with no known interaction with Fn receptor; and a 140-kDa Fn-f which is the least potent and has a RGDS sequence which can bind to the α5β1 integrin. Confocal studies showed that Fn-fs caused diffusion of α5β 1 integrin clusters which were seen …
Neural Characteristics Of Affectionate Communicators: Trait Affection And Asymmetry In The Prefrontal Cortex, Robert Joel Lewis
Neural Characteristics Of Affectionate Communicators: Trait Affection And Asymmetry In The Prefrontal Cortex, Robert Joel Lewis
Theses
Individual differences in thresholds for affectionate communication should be reflected by differences in neurological structure and function. A theoretical schema from several overlapping literatures including evolutionary psychology, social neuroscience, fundamental personality, and communication are examined to make the case that high-affection communicators have greater relative electrical activity in the left prefrontal cortex (PFC) versus the right PFC reflected in asymmetrical baseline EEG recordings. Participants (N=16) reported trait-affection levels using Floyd?s (2002) TAS-G, which measures an individual?s threshold for expressing affection. Participants? baseline electrical activity was then recorded. Asymmetry was operationalized as the difference between microvolt (μV) values of laterally opposed …
Regulation Of Pro-Inflammatory Responses By Ligands Of The Nuclear Receptor Pparγ, Andrew P. Woster
Regulation Of Pro-Inflammatory Responses By Ligands Of The Nuclear Receptor Pparγ, Andrew P. Woster
Theses and Dissertations
Inflammation-related neurotoxicity is evident in a number of different models neurodegenerative conditions, including Alzheimer's and Parkinson's diseases, Multiple Sclerosis, and HIV-associated dementia. Peroxisome proliferator-activated receptor gamma (PPARγ) agonists inhibit a number of select pro-inflammatory changes in models of CNS and systemic inflammation. Recent reports suggest that these anti-inflammatory effects are due to mechanisms other than canonical nuclear receptor-mediated transcriptional alteration. Results reported here demonstrate that rosiglitazone, a PPARγ-activating thiazolidinedione, decreases tumor necrosis factor α (TNFα) secretion in both primary microglia and the monocytic cell line, THP-1. Cells were pretreated with various PPARγ ligands, including rosiglitazone, prior to stimulation with lipopolysaccharide …
Governors State University Board Of Trustees Meeting Minutes - April 18, 2008, Board Of Trustees
Governors State University Board Of Trustees Meeting Minutes - April 18, 2008, Board Of Trustees
Board of Trustees Meetings Materials and Recordings
Agenda for the Governors State University Board of Trustees Meeting with Committees, and Minutes for the Governors State University Board of Trustees Meeting - April 18, 2008
Light Induced Changes In The Photoreceptor Outer Segments, Vikram Palamalai
Light Induced Changes In The Photoreceptor Outer Segments, Vikram Palamalai
Theses and Dissertations
Light induced retinal degeneration in animals has been used to study human retinal degenerative disorders. Apoptosis is the final common pathway for photoreceptor degeneration in both the experimental model and human disease but the mechanism is unknown. Oxidative stress plays a role because antioxidants have been shown to be protective against experimental degeneration. Inhibitors of nitric oxide synthases (NOS) are also protective suggesting a role for nitric oxide. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) a key enzyme in glycolysis was identified as one of the proteins undergoing significant nitration in our studies on light induced retinal degeneration. This study focuses on the changes …
Um Research Conference Award Winners Announced, University Of Montana--Missoula. Office Of University Relations
Um Research Conference Award Winners Announced, University Of Montana--Missoula. Office Of University Relations
University of Montana News Releases, 1928, 1956-present
No abstract provided.
Chanticleer | Vol 56, Issue 26, Jacksonville State University
Chanticleer | Vol 56, Issue 26, Jacksonville State University
Chanticleer
No abstract provided.
Nor'easter News Volume 1 Issue 6, Nor'easter News Staff
Nor'easter News Volume 1 Issue 6, Nor'easter News Staff
Nor'easter News
The sixth issue of the University of New England's student-run newspaper, Nor'easter News.
Spartan Daily, April 17, 2008, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily, April 17, 2008, San Jose State University, School Of Journalism And Mass Communications
Spartan Daily (School of Journalism and Mass Communications)
Volume 130, Issue 43
College Senate Minutes April 17, 2008, Bronx Community College Senate
College Senate Minutes April 17, 2008, Bronx Community College Senate
BCC Governance Archives
Minutes for the meeting of the College Senate on April 17, 2008.
Faculty Senate Minutes April 17, 2008, Missouri University Of Science And Technology Faculty Senate
Faculty Senate Minutes April 17, 2008, Missouri University Of Science And Technology Faculty Senate
Minutes & Agendas
No abstract provided.
Prospectus, April 17, 2008, Kathleen Serino, Briana Stodden, Chuck Shepherd, Aaron Geiger, Beth Voigt, Jason Hardimon, Shane Swearingen, Gavin J. Dow
Prospectus, April 17, 2008, Kathleen Serino, Briana Stodden, Chuck Shepherd, Aaron Geiger, Beth Voigt, Jason Hardimon, Shane Swearingen, Gavin J. Dow
Prospectus 2008
No abstract provided.
Ay 07-08 Meeting 2008-04-17, Faculty Senate
Ay 07-08 Meeting 2008-04-17, Faculty Senate
Faculty Senate Minutes
No abstract provided.
April 17, 2008, James Madison University
April 17, 2008, James Madison University
The Breeze, 2000-2009
The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.
Population Dynamics Of Freshwater Invertebrates In Beltrami County, Amanda Johnson
Population Dynamics Of Freshwater Invertebrates In Beltrami County, Amanda Johnson
Honors Capstones
Capstone submitted as a graduate requirement for the BSU Honors Program.
The Setonian, April 17, 2008, Seton Hall University
Illinois State University Report, April 17, 2008, Illinois State University
Illinois State University Report, April 17, 2008, Illinois State University
Illinois State University Report (1966-2012)
Illinois State University bi-weekly employee newsletter.
Former Grisham Writer-In-Residence Janisse Ray Returns To Speak April 24, Rebecca Lauck Cleary
Former Grisham Writer-In-Residence Janisse Ray Returns To Speak April 24, Rebecca Lauck Cleary
University of Mississippi News
OXFORD, Miss. - Passion for the environment and literature come together in a lecture Thursday (April 24) at the University of Mississippi.
The Pan American (2008-04-17), Sandra Gonzalez
The Pan American (2008-04-17), Sandra Gonzalez
UTPA Archives - The Pan American Newspaper
59th Year, No. 27
The Effects Of Perchlorate Exposure On A Model Vertebrate Species: The Threespine Stickleback, Richard R. Bernhardt
The Effects Of Perchlorate Exposure On A Model Vertebrate Species: The Threespine Stickleback, Richard R. Bernhardt
Biological Sciences
Few studies have examined the effects of chronic perchlorate exposure during multiple stages of development, and fewer still have analyzed the effects of perchlorate over multiple generations. Perchlorate exposure is known to cause thyrocyte hypertrophy (suggesting glandular stimulation), interference with thyroid hormone synthesis, and ultimately altered levels of circulating thyroid hormones, but whether these effects represent adaptive mechanisms or actual impairment is often debated within the scientific community. My research attempts to clarify whether exposure to environmentally relevant concentrations of perchlorate cause impairment at the organismal level. I examine ecologically significant endpoints to provide an indication if a contaminated population …
Surface Structure Of Hydrated And Iron(Ii) Reacted Hematite(11(-)02) And (0001), Kunaljeet S. Tanwar
Surface Structure Of Hydrated And Iron(Ii) Reacted Hematite(11(-)02) And (0001), Kunaljeet S. Tanwar
Chemistry and Biochemistry
Reactions on naturally abundant hematite (alpha-Fe2O 3) surfaces significantly influence the transport and bio-availability of a number of important nutrients and contaminants. The surface reactivity of alpha-Fe2O3 is dependent on the surface structure, i.e. the identity and coordination of chemical moieties exposed at the surface. The surface structure is strongly influenced by the presence of water and common aqueous species such as Fe(II). Therefore, it is important to understand how the surface structure evolves in the presence of water and aqueous species (e.g. Fe(II)) in order to model the surface reactivity of hematite in natural aquatic systems. The current study …
A Narrative Study Of The Lived Experience Of Contemporary American Women In Intimate Relationships With Men Who Have Chronic Low Back Pain, Gina Heath
Communication
Everyone experiences pain to one degree or another, but pain that has outlived its usefulness in assisting the body to avoid injury, and causes other physical and emotional complications, is known as chronic pain. In American medicine, chronic pain is described as that which persists longer than six months and is not relieved by standard medical care. Chronic pain usually leads to a spectrum of other physical and emotional complications, including sleep disturbance, loss of appetite, and severe depression, among many others. Creating and maintaining relationships with others takes effort and energy, and this is especially true in a marital …
Who Is In Charge Here? A Feminist Communicology Of Followership And Leadership In An Academic Organization, Robert Locke Jordan
Who Is In Charge Here? A Feminist Communicology Of Followership And Leadership In An Academic Organization, Robert Locke Jordan
Communication
This feminist critical study explicates the ways that followership is conceptualized at an academic organization in the Pacific Northwest. Through the use of qualitative methods, stories were solicited providing descriptions of events that define the hegemonically masculine ways that followership is conceptualized, suggesting the need for a feminist critical analysis and revisioning. A number of themes emerged from conversational interviews including: conceptual verisimilitude, archetypes of leadership, alternative conceptions of followership, the role of action in leadership and followership, and the emergent organization. The capta gathered from this qualitative study suggest a revisioning of human organization and recognizes leadership and followership …