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Most Downloaded Documents For June 2008, University Of Nebraska–Lincoln Digital Commons

Institutional Repository Information

Shows the 199 most-downloaded documents for the month of June 2008 from http://digitalcommons.unl.edu
For the month, 123,338 downloads of open-access documents were furnished (a new high).
81% of available documents were downloaded at least once.
The average number of downloads per available document was 8.0.

The top 15 were: VOLE CONTROL IN THE EASTERN UNITED STATES - 1,231
Arthur Paul Afghanistan Collection Bibliography - Volume II: English and European Languages (2000)- 736
The Constitutions of the Free-Masons (1734). An Online Electronic Edition - 460
EFFECTS OF OFFSHORE OIL AND GAS DEVELOPMENT: A CURRENT AWARENESS BIBLIOGRAPHY - 417
A REMARKABLE NEW …

Promotion Of Tumor Cell Death Through The Induction Of, Tuyen Nguyen

Theses and Dissertations

Microtubule poisons have proven to be effective in the treatment of a variety of malignancies. Although taxol-based derivatives promote microtubule stabilization, there is continuing interest in compounds that, like colchicines, act as microtubule destabilizing agents. Previous work from this laboratory showed that the novel microtubule poison, JG- 03-14, was active against breast tumor cells, promoting autophagic cell death. In the current work, we studied the influence of JG-03-14 on p53 wild type HCT116 colon carcinoma cells. A crystal violet sensitivity assay indicated that JG-03-14 induced growth inhibition, with 75% suppression of growth evident at a concentration of 500 nM. Time …

Directed Self-Assembly Of Gold Nanorods Using Surface Modification, David A. Walker

USF Tampa Graduate Theses and Dissertations

Metallic nanoparticles are unique materials for optical, electronic, catalytic, and sensing applications. Due to the vast flexibility in controlling the surface chemistry of these particles through functionalization there is a great deal of interest in using metallic nanoparticles as building blocks in the development of more complex nanostructures through the use of a 'bottom-up' approach. Using self assembly techniques, one can exploit spontaneous chemical interactions to build complex constructs on the nanometer scale.

Towards this end, gold nanorods have been synthesized and modified with various polymers, inorganic oxides and organic ligands to establish principles for self-assembly of these unique nanomaterials. …

Phoenix, 2008-07-09, Student Life

Phoenix

The Phoenix is a student newspaper published at Governors State University since August 2002. The newspaper features student reporting, opinions, news, and photos.

Social Representations Among Health Professionals On Sexual Violence Against Women: A Study Conducted In Three Public Maternity Hospitals In Rio De Janeiro, Brazil, L Fontenele, R Gomes, M C. Minayo

English

Objectives: To analyze the social representations of sexual violence against women held by health professionals in Rio de Janeiro.

Highly Efficient Circulating Tumor Cell Isolation From Whole Blood And Label-Free Enumeration Using Polymer-Based Microfluidics With An Integrated Conductivity Sensor, André A. Adams, Paul I. Okagbare, Juan Feng, Matuesz L. Hupert, Don Patterson, Jost Götten, Robin L. Mccarley, Dimitris Nikitopoulos, Michael C. Murphy, Steven A. Soper

Faculty Publications

A novel microfluidic device that can selectively and specifically isolate exceedingly small numbers of circulating tumor cells (CTCs) through a monoclonal antibody (mAB) mediated process by sampling large input volumes (≥1 mL) of whole blood directly in short time periods (<37 >min) was demonstrated. The CTCs were concentrated into small volumes (190 nL), and the number of cells captured was read without labeling using an integrated conductivity sensor following release from the capture surface. The microfluidic device contained a series (51) of high-aspect ratio microchannels (35 μm width x 150 μm depth) that were replicated in poly(methyl methacrylate), PMMA, from …

Volume 45, Number 46: July 09, 2008, University Of North Dakota

University Letter Archive

No abstract provided.

Susceptibility To Glaucoma: Differential Comparison Of The Astrocyte Transcriptome From Glaucomatous African American And Caucasian American Donors, Thomas J. Lukas, Haixi Miao, Lin Chen, Sean M. Riordan, Wenjun Li, Andrea M. Crabb, Alexandria Wise, Pan Du, Simon M. Lin, M Rosario Hernandez

Publications and Research

Comparison of gene expression in normal and glaucomatous eyes from Caucasian American and African American donors reveals differences that might reflect different susceptibility to glaucoma.

Using A Chelator-Buffered Nutrient System To Study Phosphorus, Manganese And Zinc Interactions In Russet Burbank Potato, Steven A. Barben

Theses and Dissertations

Potato production requires high phosphorus (P) application with potential negative environmental or nutritional consequences for potato as well as for subsequent crops. Impacts of high available P on yield and plant nutrition of species in potato cropping rotations are inadequately understood, and could result in antagonistic interactions with cationic micronutrients such as zinc (Zn) and manganese (Mn). Three hydroponic experiments were conducted with Russet Burbank potato to elucidate P and Zn relationships and associated interactions with other nutrients. In the first experiment, P solution concentration was constant at 256 µM while Zn concentration varied: 0.1, 2, 6, 18, 54, 162 …

Sequence Information Encoded In Dna That May Influence Long-Range Chromatin Structure Correlates With Human Chromosome Functions., Taichi E. Takasuka, Alfred Cioffi, Arnold Stein

Department of Biological Sciences Faculty Publications

Little is known about the possible function of the bulk of the human genome. We have recently shown that long-range regular oscillation in the motif non-T, A/T, G (VWG) existing at ten-nucleotide multiples influences large-scale nucleosome array formation. In this work, we have determined the locations of all 100 kb regions that are predicted to form distinctive chromatin structures throughout each human chromosome (except Y). Using these data, we found that a significantly greater fraction of 300 kb sequences lacked annotated transcripts in genomic DNA regions ≥300 kb that contained nearly continuous chromatin organizing signals than in control regions. We …

Disciplinarization Of The Mouth, The Autonomy Of The Individual In A Working Society, D Kovaleski, S Torres, C Botazzo

English

Objectives: To analyze the dental health-illness process using the "buccality" concept proposed by Botazzo.

Knowledge, Awareness And Practices Regarding Dengue Fever Among The Adult Population Of Dengue Hit Cosmopolitan., Ahmed Itrat, Abdullah Khan, Sunniya Javaid, Mahwash Kamal, Hassan Khan, Sannia Javed, Saira Kalia, Adil Haleem Khan, Muhammad Imran Sethi, Imtiaz Jehan

Community Health Sciences

Background: The World health Organization (WHO) declares dengue and dengue hemorrhagic fever to be endemic in South Asia. Despite the magnitude of problem, no documented evidence exists in Pakistan which reveals the awareness and practices of the country's adult population regarding dengue fever, its spread, symptoms, treatment and prevention. This study was conducted to assess the level of knowledge, attitudes and practices regarding dengue fever in people visiting tertiary care hospitals in Karachi, Pakistan.
Methods: A cross-sectional pilot study was conducted among people visiting tertiary care hospitals in Karachi. Through convenience sampling, a pre-tested and structured questionnaire was administered through …

Body Shape Dissatisfaction: Patterns Of Concern Among Subgroups Of College Freshmen Women, Kristina S Withers Hansen

Theses and Dissertations

This study seeks to determine if there are patterns of differences according to college major in terms of the percentage of freshmen women who score in the clinically significant range on a measure of attitude toward body shape. Participants (N = 1,982) completed a demographic questionnaire and the Body Shape Questionnaire (BSQ) and were divided into subgroups according to their stated college major. Descriptive statistics regarding BSQ scores were calculated for the total sample and subgroups. Results indicated that a greater percentage of participants in Theater, Communications, Psychology, Dance, Business, and Dietetics majors scored within clinically significant ranges on the …

Role Of Foxo Factors As The Nuclear Mediator For Pten-Ar Antagonism In Prostate Cancer Cells, Qiuping Ma

USF Tampa Graduate Theses and Dissertations

FoxO proteins are transcriptional factors acting downstream of the tumor suppressor PTEN. Their activity is negatively regulated by AKT-mediated phosphorylation. Our previous studies showed a mutual suppression between PTEN and the androgen receptor (AR) in regulating growth and apoptosis in prostate cancer (PCa) cells. We hypothesize that nuclear FoxO proteins are involved in mediating this mutual antagonism. In this dissertation, we report that PTEN inhibits AR activity through FoxO1 and provide evidence for the involvement of FoxO factors in the androgen-mediated suppression of PTEN-induced apoptosis. Our studies identify a novel mechanism for AR inhibition by FoxO1 and demonstrated the participation …

The Bg News July 9, 2008, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. July 9, 2008. Volume 98-Issue 159.

Structural Diversity In Metal-Organic Materials, Gregory J. Mcmanus

USF Tampa Graduate Theses and Dissertations

The interest in metal-organic materials namely, coordination polymers and metal-organic frameworks has risen dramatically over the past few years. To a certain extent this interest is a consequence of the realization chemists have discovered how to play a form of molecular Lego® in which metal cations or metal clusters represent the bricks (or nodes) and organic ligands such as 4,4-bipyridine (bipy) or benzene-dicarboxylate represents the glue (or spacers). The "node-and-spacer" approach to self-assembly can be invoked in such a manner that a plethora of infinite architectures and discrete polyhedra can be generated from geometric principles, some of which are unprecedented …

Gardens At Home, Gardens At School: Diet And Food Crop Diversity In Two Q'Eqchi' Communities In Southern Belize, Douglas Carl Reeser

USF Tampa Graduate Theses and Dissertations

A district-wide school garden project has been initiated in the Toledo District of Southern Belize in response to reported high rates of poverty and undernutrition. This paper will discuss research conducted in the summer of 2007 with Q'eqchi' Maya in the Toledo District to determine the effect of school gardens on household diet and gardening, the composition of the household diet, and the makeup of homegardens. Food frequency questionnaires and semi-structured interviews were conducted in two rural villages, one with a school garden program and one without. Various members of NGOs working on school garden projects in the district were …

University Of Montana Events Monday, July 14, Through Monday, July 28, 2008, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Meeting Minutes, Wku Council Of Academic Deans

Council of Academic Deans

Meeting regarding campus events, Faculty House, awards, 120 hour degree, scholarships, workdays, position announcement uniformity, student retention and student recruitment.

Fathers: A Contemporary Perspective On Their Role In Child-Driven Materialism, Catriona Nash, Serge Basini

Conference proceedings

This paper explores the contemporary role of fathers in child-driven materialistic consumption, a little explored territory. Commencing with an exploration of the child consumer and their influence in personal and family spending, both of which have grown considerably over that last number of decades, followed by an analysis of changes in families and the role fathers now play in the aforementioned. It is also acknowledged that fathers have previously been ignored to a large extent in the majority of research studies concerning parent-child consumption and purchases. As such, valuable insights emerged through an interpretative framework utilised to explore this area. …

Proteome Discovery Pipeline For Mass Spectrometry-Based Proteomics, Erik Gough

Bindley Publications

We have developed the Proteome Discovery Pipeline, a stand-alone bioinformatics platform used for LC/MS data analysis and biomarker discovery. Data is processed in a series of self-contained analytical steps using modules that are controlled by a graphical user interface. The user interface was developed in Visual C++ 6.0 and provides a multi-threaded, tabbed user interface with each tab representing a step in the analysis process. Modules included are spectrum deconvolution, alignment, normalization, significance tests and pattern recognition. Modules consist of applications developed in C++ and the R scripting language, which are called as external processes from the GUI using inputted …

Genomic Analysis Of Gene Regulation Complexity, Brandon Barker, Jim Lund

Biology Presentations

With multiple metazoan genomes in each family being sequenced promoter analysis is becoming a useful tool in genomic analysis. Aligning the promoter regions in the DNA of C. elegans and C. briggsae identifies conserved promoter elements. While not all promoter elements are conserved and not all conserved regions are promoter elements, we find that conservation is a useful method for determining promoter complexity. Promoter complexity identifies which genes have particularly interesting regulation, identifying gene groups with a strong promoter complexity signal and cases where a gene's promoter complexity differs from the group's promoter complexity.

We identify potential promoter sequence by …

Identifying Regulatory Elements And Gene Boundaries With Comparative Genomic Sequence Analysis, Jim Lund

Biology Presentations

For several groups of organisms multiple genomes have been sequenced either completely or to the unfinished shotgun sequencing stage. Comparative sequence analysis can identify functional sequence elements for pairs of organisms that diverged far enough in the past to allow mutational drift of non-conserved sequences. While analysis of a pair of genomes identifies many of these functional elements adding additional genomes allows additional information to be elicited.

Additional conserved sequence elements are identified as additional genomes are analyzed. These conserved sequence elements are often regulatory elements although they are difficult to classify with in silico analysis. For an individual gene, …

The Daily Egyptian, July 08, 2008, Daily Egyptian Staff

July 2008

No abstract provided.

Surface Charge Effects Involved In The Control Of Stability Of Sols Comprising Uniform Cholesterol Particles, Vuk Uskoković

Pharmacy Faculty Articles and Research

The reported is a method for the preparation of stable dispersions of narrowly dispersed cholesterol crystals, which may provide an excellent model for the aggregation studies thereof. The effects of experimental parameters that include concentration, pH, ionic strength, temperature, and aging on the resulting morphologies are acknowledged. Regardless of the cause of destabilization, the multilayered aggregates of cholesterol particles are formed by “face-to-face” stacking of the original platelets, as promoted by higher surface charge density on particle sides comparing to their faces. In accordance with the crucial involvement of surface charge effects in stabilization of cholesterol dispersions produced hereby, aggregation …

Effect Of Ca And Ph On Disease Severity Of Pink Rot Phytophthora Erythroseptica In Russett Norkotah Potato Solanum Tuberosum, Jared H. Benson

Theses and Dissertations

Phytophthora erythroseptica Pethyb. is a devastating fungal pathogen of potato (Solanum tuberosum). The pathogen causes a disease known as pink rot. Pink rot results in necrosis and decay of tubers; and is responsible for major losses pre and post harvest. Attributes of the disease are progressing toward epidemic proportions. To help prevent such dramatic outbreaks of the disease, understanding the factors associated with incidence will provide opportunities to control the pathogen. A link between pH and disease severity has been observed. We studied the effects of pH and Ca to determine their influence on disease development. Low pH and Ca …

Mitochondrial Dna Evolution In The Anaxyrus Boreas Species Group, Anna M. Goebel, Tom A. Ranker, Paul Stephen Corn, Richard G. Olmstead

United States Geological Survey: Staff Publications

The Anaxyrus boreas species group currently comprises four species in western North America including the broadly distributed A. boreas, and three localized species, Anaxyrus nelsoni, Anaxyrus exsul and Anaxyrus canorus. Phylogenetic analyses of the mtDNA 12S rDNA, cytochrome oxidase I, control region, and restriction sites data, identified three major haplotype clades. The Northwest clade (NW) includes both subspecies of A. boreas and divergent minor clades in the middle Rocky Mountains, coastal, and central regions of the west and Pacific Northwest. The Southwest (SW) clade includes A. exsul, A. nelsoni, and minor clades in southern California. …

A Compliant Threshold Acceleration Sensor Integrated With Radio Frequency Identifiable Tags, Benjamin L. Todd

Theses and Dissertations

Fully compliant bistable mechanisms have been proposed to be used as threshold accelerometers. The advantages to using these devices are that they require no external power to operate and maintain their sensing state. Using this characteristic the devices can be integrated with passive radio frequency identification tags (RFID). This allows for the sensing package to lay dormant with no maintenance needed until the sensor is read by the RFID reader. This thesis presents a successfully fabricated and integrated threshold accelerometer with a passive RFID tag. This in turn has been successfully read with an RFID reader and shown to act …

Can Using One Trainer Solely To Deliver Prompts And Feedback During Role Plays Increase Correct Performance Of Parenting Skills In A Behavioral Parent Training Program?, Michael M. Cripe

USF Tampa Graduate Theses and Dissertations

Behavioral Parent Training refers to a broad range of instructional programs that teach parents and other caregivers ways to build and change behavioral repertoires of children. Most, if not all, such programs employ Behavioral Skills Training (modeling, prompting, role-play practice and feedback) to teach parenting skills. However, specific ways to use prompting during role plays have not been described in the behavioral parent training literature. The present study compared two methods of conducting role plays during parent training. A between group, pretest/posttest design was used to evaluate and compare the effect of using one versus two trainers on the role-play …

Foreign Citizens: Freedmen, Identity, And Cultural Belonging In The Early Empire, Hayley Steptoe

Studies in Mediterranean Antiquity and Classics

No abstract provided.