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Genetic Characterization Of Feline Leukemia Virus From Florida Panthers, Meredith Brown, Mark W. Cunningham, Alfred L. Roca, Jennifer L. Troyer, Warren E. Johnson, Stephen J. O'Brien

Biology Faculty Articles

From 2002 through 2005, an outbreak of feline leukemia virus (FeLV) occurred in Florida panthers (Puma concolor coryi). Clinical signs included lymphadenopathy, anemia, septicemia, and weight loss; 5 panthers died. Not associated with FeLV outcome were the genetic heritage of the panthers (pure Florida vs. Texas/Florida crosses) and co-infection with feline immunodeficiency virus. Genetic analysis of panther FeLV, designated FeLV-Pco, determined that the outbreak likely came from 1 cross-species transmission from a domestic cat. The FeLV-Pco virus was closely related to the domestic cat exogenous FeLV-A subgroup in lacking recombinant segments derived from endogenous FeLV. FeLV-Pco sequences were …

Rapid Preclinical Detection Of Sheeppox Virus By A Real-Time Pcr Assay, C. A. Balinsky, Gustavo A. Delhon, G. Smoliga, M. Prarat, R. A. French, S. J. Geary, S. J. Geary, D. L. Rock, L. L. Rodriguez

Nebraska Center for Virology: Faculty Publications

Sheeppox virus (SPPV) is a member of the Capripoxvirus (CaPV) genus of the Poxviridae family. Members of this genus, which also include goatpox and lumpy skin disease viruses, cause economically significant disease in sheep, goats, and cattle. A rapid diagnostic assay for CaPV would be useful for disease surveillance as well as for detection of CaPV in clinical samples and for outbreak management. Here we describe a fluorogenic probe hydrolysis (TaqMan) PCR assay designed for rapid detection of CaPV and tested on sheep experimentally infected with a virulent strain of SPPV. This assay can detect SPPV in buffy coats, nasal …

The Role Of Phylogeny And Ecology In Experimental Host Specificity: Inisights From A Eugregarine-Host System, Jillian Tikka Detwiler, John J. Janovy Jr.

John J. Janovy, Jr. Publications

The degree to which parasites use hosts is fundamental to host–parasite coevolution studies, yet difficult to assess and interpret in an evolutionary manner. Previous assessments of parasitism in eugregarine–host systems suggest high degrees of host specificity to particular host stages and host species; however, rarely have the evolutionary constraints on host specificity been studied experimentally. A series of experimental infections were conducted to determine the extent of host stadium specificity (larval vs. adult stage) and host specificity among 6 tenebrionid host species and 5 eugregarine parasite species. Eugregarines from all host species infected both the larva and adult stages of …

Transfusion-Transmitted Malaria In A Kidney Transplant Recipient. How Safe Is Our Blood Transfusion?, Ahmed M. Alkhunaizi, Jaffar A. Al-Tawfiq, Mohannad H. Al-Shawaf

Saudi Medical Journal

A 51-year-old male patient with living, unrelated kidney transplantation in Iran in June 2001, developed Plasmodium falciparum P. falciparum infection. He was maintained on cyclosporine A, mycophenolate mofetil, and prednisone. In August 2005, he was admitted to a medical facility in the local community with upper gastrointestinal bleeding, and received several units of blood and blood products. Two months later, he was referred to Dhahran Health Center, and admitted with fever, abdominal pain, dysuria, and severe fatigue. Plasmodium falciparum with a parasitemia of 70% was detected in the peripheral smear. He was treated with intravenous quinidine gluconate and oral doxycycline, …

A Tick From A Prehistoric Arizona Coprolite, Keith L. Johnson, Karl J. Reinhard, Luciana Sianto, Adauto Araújo, Scott Lyell Gardner, John J. Janovy Jr.

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Ticks have never been reported in archaeological analyses. Here, we present the discovery of a tick from a coprolite excavated from Antelope Cave in extreme northwest Arizona. Dietary analysis indicates that the coprolite has a human origin. This archaeological occupation is associated with the Ancestral Pueblo culture (Anasazi). This discovery supports previous hypotheses that ticks were a potential source of disease and that ectoparasites were eaten by ancient people.

Two Cyclocoelids From The Lesser Yellowlegs, Tringa Flavipes (Scolopacidae), From The Central Flyway Of North America, Including The Description Of Haematotrephus Selfi N. Sp. (Digenea: Cyclocoelidae), Norman O. Dronen, Scott Lyell Gardner, F. Agustin Jimenez-Ruiz

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Seven specimens of cyclocoelids (6 specimens representing Haematotrephus selfi n. sp. and 1 specimen representing a second unidentified species of Haematotrephus) collected by the late Dr. J. Teague Self, former professor, Department of Zoology, University of Oklahoma, Norman, Oklahoma, U.S.A., from the body cavities of 3 lesser yellowlegs, Tringa flavipes, (2 birds collected from Roger Mills County, Oklahoma on 23 and 29 August 1963, and 1 collected from Manitoba, Canada on 3 June 1964) and deposited in the Manter Laboratory of Parasitology, University of Nebraska, Lincoln, Nebraska are described. Haematotrephus selfi n. sp. can be distinguished from all …

Focal White Matter Changes In Spasmodic Dysphonia: A Combined Diffusion Tensor Imaging And Neuropathological Study, Kristina Simonyan, Fernanda Tovar-Moll, John Ostuni, Mark Hallett, Victor F Kalasinsky, Michael R Lewin-Smith, Elisabeth J Rushing, Alexander O Vortmeyer, Christy L Ludlow

Faculty, Staff and Student Publications

Spasmodic dysphonia is a neurological disorder characterized by involuntary spasms in the laryngeal muscles during speech production. Although the clinical symptoms are well characterized, the pathophysiology of this voice disorder is unknown. We describe here, for the first time to our knowledge, disorder-specific brain abnormalities in these patients as determined by a combined approach of diffusion tensor imaging (DTI) and postmortem histopathology. We used DTI to identify brain changes and to target those brain regions for neuropathological examination. DTI showed right-sided decrease of fractional anisotropy in the genu of the internal capsule and bilateral increase of overall water diffusivity in …

Aging And Inflammation In Two Epidemiological Worlds, Michael Gurven, Hillard Kaplan, Jeffrey Winking, Caleb Finch, Eileen M. Crimmins

ESI Publications

Humans evolved in a world with high levels of infection resulting in high mortality across the life span and few survivors to advanced ages. Under such conditions, a strong acute-phase inflammatory response was required for survival; however, inflammatory responses can also promote chronic diseases of aging. We hypothesize that global historical increases in life span at older ages are partly explained by reduced lifetime exposure to infection and subsequent inflammation. To begin a test of this hypothesis, we compare C-reactive protein (CRP); levels in two populations with different epidemiological environments: the Tsimane of Bolivia and persons in the United States. …

Food Safety Education As A Risk Management Strategy, Deborah L. Angell

Journal of Extension

What would the consequences be if food at an Extension event caused a food borne illness outbreak? Programs and activities involving the service or preparation of food are common in Extension programs and provide inherent risks that, if not managed, could lead to potential financial loss or harm to people, property, or organizational goodwill. Ohio State University Extension has taken a proactive approach to food safety risk management by adopted Food Preparation/Service Policy and Procedures, requiring training, using The Original Safe Food Handling for Occasional Quantity Cooks curriculum, for all Extension staff and volunteers involved with food programs or events.

The Great Divide: Socioeconomics And Healthcare, Daniel Ruth

Reason and Respect

Socioeconomics is an important factor in determining whether a country is receiving proper healthcare and adequate supplies for the future. Personal economics in relation to healthcare is an issue that often inspires a debate that focuses on the AIDS epidemic in Africa; however, socioeconomics also has a key function in the provision of aid for many other diseases globally.

Rich Honored For Life's Work, Staff

Browse All News

No abstract provided.

Portable Housing For Mexican Migrant Workers, Janet Corzo

Theses

A capable migrant labor force is critical in sustaining the United States' agriculture industry. Yet, migrant farm workers are among the most economically disadvantaged people in the United States (NCFH). The housing available to migrant workers in the United States is typically substandard and subject to other factors, such as local availability, social stigmas and legal status. While housing is usually provided by a grower (on-the-farm) or acquired by the migrant worker himself (off-the-farm), there seem to exist no examples of portable housing that a worker can transport from job to job. This study seeks to explore the viability of …

Using Wavelet And Template Analysis To Classify Hand Postures In Unsupervised Daily Activities, Soha Hassan Saleh

Theses

This project's goal was to identify determinants that characterize different types of activities an individual do in daily life, knowing the quality of hand function is essential to plan more effective rehabilitation therapies and treatments for upper limb movement disorders. The first part of the project was Jebsen-Taylor study where healthy individuals and individuals with brain injury performed seven activities classified as precision grasp, cylindrical grasp, and palmar grasp while metacarpal joint angles were measured in real time. The data from those seven activities was used to determine parameters that characterize each type of activity and which might be used …

Vol.35 N.35 January 24th 2008, Brown Publishing Company

Black Voice News

No abstract provided.

Molecular Studies In Treponema Pallidum Evolution: Toward Clarity?, Connie J. Mulligan, Steven J. Norris, Sheila A. Lukehart

Faculty, Staff and Student Publications

No abstract provided.

Current, January 22, 2008, University Of Missouri-St. Louis

Current (2000s)

No abstract provided.

In Vitro Analysis Of Tobramycin-Treated Pseudomonas Aeruginosa Biofilms On Cystic Fibrosis-Derived Airway Epithelial Cells, Gregory G. Anderson, Sophie Moreau-Marquis, Bruce A. Stanton, George A. O'Toole

Dartmouth Scholarship

P. aeruginosa forms biofilms in the lungs of individuals with cystic fibrosis (CF); however, there have been no effective model systems for studying biofilm formation in the CF lung. We have developed a tissue culture system for growth of P. aeruginosa biofilms on CF-derived human airway cells that promotes the formation of highly antibiotic-resistant microcolonies, which produce an extracellular polysaccharide matrix and require the known abiotic biofilm formation genes flgK and pilB. Treatment of P. aeruginosa biofilms with tobramycin reduced the virulence of the biofilms both by reducing bacterial numbers and by altering virulence gene expression. We performed microarray analysis …

Statistical Methods For Automated Drug Susceptibility Testing: Bayesian Minimum Inhibitory Concentration Prediction From Growth Curves, Xi Zhou, Merlise A. Clyde, James Garrett, Viridiana Lourdes, Michael O'Connell, Giovanni Parmigiani, David J. Turner, Tim Wiles

Johns Hopkins University, Dept. of Biostatistics Working Papers

Determination of the minimum inhibitory concentration (MIC) of a drug that prevents microbial growth is an important step for managing patients with infections. In this paper, we present a novel probabilistic approach that accurately estimates MICs based on a panel of multiple curves reflecting features of bacterial growth. We develop a probabilistic model for determining whether a given dilution of an antimicrobial agent is the MIC given features of the growth curves over time. Because of the potentially large collection of features, we utilize Bayesian model selection to narrow the collection of predictors to the most important variables. In addition …

The Bg News January 17, 2008, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 17, 2008. Volume 98-Issue 85.

The Spinnaker Vol. 31 No. 19, University Of North Florida

Spinnaker

Student newspaper for the UNF community

Microbes And The Days Of Creation, Alan L. Gillen

Faculty Publications and Presentations

The world of germs and microbes has received much attention in recent years. But where do microbes fit into the creation account? Were they created along with the rest of the plants and animals in the first week of creation, or were they created later, after the Fall? These are some questions that creation microbiologists have been asking in recent years. Ongoing research, based on the creation paradigm, appears to provide some answers to these puzzling questions. The answers to these questions are not explicit in Scripture, so the answers cannot be dogmatic. However, a reasonable extrapolation from biological data …

A Tick From A Prehistoric Arizona Coprolite (Galley Proofs), Keith L. Johnson, Karl J. Reinhard, Luciana Sianto, Adauto Araújo, Scott Lyell Gardner, John J. Janovy Jr.

School of Natural Resources: Faculty Publications

Ticks have never been reported in archaeological analyses. Here, we present the discovery of a tick from a coprolite excavated from Antelope Cave in extreme northwest Arizona. Dietary analysis indicates that the coprolite has a human origin. This archaeological occupation is associated with the Ancestral Pueblo culture (Anasazi). This discovery supports previous hypotheses that ticks were a potential source of disease and that ectoparasites were eaten by ancient people.

Antiretroviral Pre-Exposure Prophylaxis Prevents Vaginal Transmission Of Hiv-1 In Humanized Blt Mice, Paul W. Denton, Jacob D. Estes, Zhifeng Sun, Florence A. Othieno, Bangdong L. Wei, Anja K. Wege, Daniel A. Powell, Deborah A. Payne, Ashley T. Haase, J. Victor Garcia

Biology Faculty Publications

Background: Worldwide, vaginal transmission now accounts for more than half of newly acquired HIV-1 infections. Despite the urgency to develop and implement novel approaches capable of preventing HIV transmission, this process has been hindered by the lack of adequate small animal models for preclinical efficacy and safety testing. Given the importance of this route of transmission, we investigated the susceptibility of humanized mice to intravaginal HIV-1 infection.

Methods and Findings: We show that the female reproductive tract of humanized bone marrow–liver–thymus (BLT) mice is reconstituted with human CD4þ T and other relevant human cells, rendering these humanized mice …

The Bg News January 15, 2008, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. January 15, 2008. Volume 98-Issue 83.

Novel Molecules For Intra-Oral Delivery Of Antimicrobials To Prevent And Treat Oral Infectious Diseases, Periathamby A. Raj, Latha Rajkumar, Andrew R. Dentino

School of Dentistry Faculty Research and Publications

New molecules were designed for efficient intra-oral delivery of antimicrobials to prevent and treat oral infection. The salivary statherin fragment, which has high affinity for the tooth enamel, was used as a carrier peptide. This was linked through the side chain of the N-terminal residue to the C-terminus of a defensin-like 12-residue peptide to generate two bifunctional hybrid molecules, one with an ester linkage and the other with an anhydride bond between the carrier and the antimicrobial components. They were examined for their affinity to a HAP (hydroxyapatite) surface. The extent of the antimicrobial release in human whole saliva was …

Parasites As Probes For Prehistoric Human Migrations? (Galley Proofs), Adauto Araújo, Karl J. Reinhard, Luiz F. Ferreira, Scott Lyell Gardner

School of Natural Resources: Faculty Publications

Host-specific parasites of humans are used to track ancient migrations. The archaeoparasitology of some intestinal parasites in the New World points to migration routes other than the Bering Land Bridge. Helminths have been found in mummies and coprolites in North and South America. Hookworms (Necator and Ancylostoma), whipworms (Trichuris trichiura) and other helminths require specific conditions for life-cycle completion. They could not survive in the cold climate of the northern region of the Americas. Therefore, humans would have lost some intestinal parasites while crossing Beringia. Evidence is provided here from published data of pre-Columbian sites for the peopling of the …

Going Too Far? Exploring The Limits Of Smoking Regulations, Simon Chapman

William Mitchell Law Review

No abstract provided.

Trust Me. I Am A Doctor. Your Records Are Safe…, Patricia A. Williams, Craig Valli

Australian Information Security Management Conference

Primary care medical practices in Australia have been identified as a profession in need of assistance with information security practices. Whilst guidelines exist, there is little assistance in an accessible and easily implemented form for medical practices. This research presents the preliminary findings of a study which advocates that information security practices can be improved using a capability operational framework which is contextualised to its target environment.

Equality Of States - Its Meaning In A Constitutionalized Global Order, Ulrich K. Preuss

Chicago Journal of International Law

The Article is divided into six sections. Section II begins with an analysis of the conceptual relation between equality and the essential element of statehood, namely the plurality of states and their formation of an unorganized or anarchical society, followed in Section III by an analysis of the significance of the status of membership in the international society for the concept of "sovereign equality" as established by the United Nations. Section IV deals with the transformations of the structure of international society from its incipient character as a horizontal or anarchical society through the League of Nations to the UNO. …

January 3, 2008 Finance & Facilities (F&F) Committee Meeting, Evp For Administration

Finance and Facilities Committee

Documents related to the January 3, 2008 Board of Regents' Finance and Facilities Committee Meeting. (Agenda, Minutes, eBook)