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The Inkwell, Armstrong Atlantic State University

The Inkwell

No abstract provided.

Perceived Similarity Between Complex Sounds: The Contribution Of Acoustic, Descriptive And Categorical Features, Kirsteen M Aldrich

School of Psychology Theses

The thesis identifies some of the most salient acoustic and descriptive features employed in listeners' representations of sounds focussing on similarity judgements. A range of descriptive data (including word pair and imagery/word use) was collected alongside acoustic measures for the sound stimuli employed. The sounds employed were initially all abstract in nature but environmental sounds were included in later experiments. A painwise comparison task and a grouping task were employed to collect (dis)similarity data for multidimensional scaling and hierarchical cluster analyses. These provided visual output that represented the sounds' perceived similarities. Following participants' similarity judgements correlational techniques identified which of …

Genetic Networks Controlling Retinal Injury, Felix R Vazquez-Chona, Amna N Khan, Chun K Chan, Anthony N Moore, Pramod K Dash, M Rosario Hernandez, Lu Lu, Elissa J Chesler, Kenneth F Manly, Robert W Williams, Eldon E Geisert

Faculty, Staff and Student Publications

PURPOSE: The present study defines genomic loci underlying coordinate changes in gene expression following retinal injury.

METHODS: A group of acute phase genes expressed in diverse nervous system tissues was defined by combining microarray results from injury studies from rat retina, brain, and spinal cord. Genomic loci regulating the brain expression of acute phase genes were identified using a panel of BXD recombinant inbred (RI) mouse strains. Candidate upstream regulators within a locus were defined using single nucleotide polymorphism databases and promoter motif databases.

RESULTS: The acute phase response of rat retina, brain, and spinal cord was dominated by transcription …

The Evidence For A Nascent Biotechnology Cluster In Cork, John W. Hobbs

Theses

Over the past 30 years, encouraged by Ireland’s low rate of corporation tax (currently 12.5 %), and active promotion of FDI by the IDA, foreign owned pharmaceutical plants have set up and multiplied in the Cork area. To Ireland’s advantages of a low tax rate, an English speaking population, a pro-business environment and membership of EU, Cork offered the added attractions of a deepwater port and large natural harbour, good freight connections, an international airport, an educated workforce and excellent sporting and leisure facilities for sailing, golf, etc. (Pfizer, Eli Lilly, Novartis, GlaxoSmithKline, Johnson & Johnson and Schering Plough have …

Exploring Marine Biotoxins Using Analytical Techniques Based On Mass Spectrometry, Mónica Fernández Amandi

Theses

The impact of phycotoxins on human and animal health is of important concern for worldwide authorities and the scientific community. Domoic acid (DA) is a neurotoxin produced by phytoplankton {Pseudonitzchia spp.). It enters the food chain through the consumption of shellfish that feed on toxic diatoms. DA has been responsible for several outbreaks affecting humans and animals all around the world. Yessotoxin (YTX) is produced by dinoflagellate species {Protoceratiuni reticulatum) which are globally distributed. Its toxicity is low when ingested orally. However, the co-extraction of YTX with diarrhetic shellfish poisoning (DSP) toxins, derives false positives when the mouse bioassay is …

Host Blood Proteins And Peptides In The Midgut Of The Tick Dermacentor Variabilis Contribute To Bacterial Control, Daniel E. Sonenshine, Wayne L. Hynes, Shane M. Ceraul, Robert Mitchell, Tiffany Benzine

Biological Sciences Faculty Publications

Antimicrobial midgut proteins and peptides that result from blood digestion in feeding American dog ticks Dermacentor variabilis (Say) were identified. Midgut extracts from these ticks showed antimicrobial activity against Micrococcus luteus, regardless of whether they were challenged with peptidoglycan, blood meal components, rabbit blood, Bacillus subtilis, Escherischia coli or Borrelia burgdorferi. However, no peptide band co-migrating with defensin was found in midgut extracts from the challenged ticks. Partial purification of the midgut extracts using C₁₈ Sep Paks and gel electrophoresis showed the presence of 4 distinct bands with rMW 4.1, 5.3, 5.7 and 8.0 kDa identified …

Demonstration Of Toxicity To Fish And To Mammalian Cells By Pfiesteria Species: Comparison Of Assay Methods And Strains, Joann M. Burkholder, Andrew S. Gordon, Peter D. Moeller, J. Mac Law, Kathryn J. Coyne, Alan J. Lewitus, John S. Ramsdell, Harold G. Marshall, Nora J. Deamer, S. Craig Cary, Jason W. Kempton, Steven L. Morton, Parke A. Rublee

Biological Sciences Faculty Publications

Toxicity and its detection in the dinoflagellate fish predators Pfiesteria piscicida and Pfiesteria shumwayae depend on the strain and the use of reliable assays. Two assays, standardized fish bioassays (SFBs) with juvenile fish and fish microassays (FMAs) with larval fish, were compared for their utility to detect toxic Pfiesteria. The comparison included strains with confirmed toxicity, negative controls (noninducible Pfiesteria strains and a related nontoxic cryptoperidiniopsoid dinoflagellate), and P. shumwayae strain CCMP2089, which previously had been reported as nontoxic. SFBs, standardized by using toxic Pfiesteria (coupled with tests confirming Pfiesteria toxin) and conditions conducive to toxicity expression, reliably detected …

Defensin In Ticks: Molecular Characterization, Expression, And Role In Innate Immunity, Daniel E. Sonenshine, Wayne L. Hynes, Shane M. Ceraul, Michelle Todd

Biological Sciences Faculty Publications

No abstract provided.

Effects Of Human Disturbances On The Behavior Of Wintering Ducks, Melissa L. Pease, Robert K. Rose, Mark J. Butler

Biological Sciences Faculty Publications

Human activity causes wintering waterfowl to expend energy to avoid humans at a time in their annual cycle when energy conservation is important to survival, migration, and breeding reserves. Understanding the effects of recreational activities on waterfowl is important to managing natural resource areas where migratory birds depend on wetland habitat for resting and feeding. We investigated responses of 7 species of dabbling ducks to 5 different experimental human activities, (a pedestrian, a bicyclist, a truck traveling at 2 different speeds, and an electric passenger tram). Responses of ducks depended on type of disturbance, species, and distance from disturbances. Most …

New Species Of Amphipod Crustaceans In The Genera Tegano And Melita (Hadzioidea : Melitidae) From Subterranean Groundwaters In Guam, Palau, And The Philippines, Thomas R. Sawicki, John R. Holsinger, Thomas M. Iliffe

Biological Sciences Faculty Publications

Three new species of Tegano are described, two from caves on Panglao Island, Bohol, Philippines, and one from a cave on Peleliu Island, Palau. Sriha vagabunda from Sri Lanka is reassigned to the genus Tegano based primarily on the high degree of similarity between Sriha vagabunda and species of Tegano and the fact that these species exhibit a great deal of variation in the reduction of the mandibular palp. A new species of Melita with characters intermediate between those defining the genera Abludomelita, Melita, and Paraniphargus is described from a spring on Guam. The characters of the new …

Mechanical Properties Of The Integument Of The Common Gartersnake, Thamnophis Sirtalis (Serpentes: Colubridae), Gabriel Rivera, Alan H. Savitzky, Jeffrey A. Hinkley

Biological Sciences Faculty Publications

The evolution of the ophidian feeding mechanism has involved substantial morphological restructuring associated with the ability to ingest relatively large prey. Previous studies examining the morphological consequences of macrophagy have concentrated on modifications of the skull and cephalic musculature. Although it is evident that macrophagy requires highly compliant skin, the mechanical properties of the ophidian integument have received limited attention, particularly in the context of feeding. We examined mechanical properties of skin along the body axis in Thamnophis sirtalis (Colubridae). Data were collected from tensile tests and were analyzed using a multivariate analysis of variance (MANOVA) and post-hoc multiple comparison …

The Many Faces Of Overcriminalization: From Morals And Mattress Tags To Overfederalization, Sara Sun Beale

Faculty Scholarship

No abstract provided.

Student Expression In The Age Of Columbine: Securing Safety And Protecting First Amendment Rights, David L. Hudson Jr.

Law Faculty Scholarship

"Student Expression in the Age of Columbine" is one in an ongoing series of First Reports, published by the First Amendment Center, on major First Amendment issues of our time.

Content And Context: The Contributions Of William Van Alstyne To First Amendment Interpretation, Rodney A. Smolla

Law Faculty Publications

William Van Alstyne’s contributions to First Amendment interpretation, like his contributions to all of American constitutional law, are characterized by a piercing intellectual honesty and an impish play of intelligence. One feels relentlessly pulled by the elegant currents of Professor Van Alsytne’s arguments, yet, at the same time, restlessly resistant, a resistance borne of the vague but certain wariness that one is but an apprentice forever consigned to a level of awareness several moves behind the master, who almost certainly will produce surprises at the end. ...

A Troubling Equation In Contracts For Government Funded Scientific Research: "Sensitive But Unclassified" = Secret But Unconstitutional, Leslie Gielow Jacobs

McGeorge School of Law Scholarly Articles

No abstract provided.

Effect Of Dietary Fatty Acid Composition On Depot Fat And Exercise Performance In A Migrating Songbird, The Red-Eyed Vireo, Barbara J. Pierce, Scott R. Mcwilliams, Timothy P. O'Connor, Allen R. Place, Christopher G. Guglielmo

Biology Faculty Publications

Most migrating birds accumulate lipid stores as their primary source of energy for fueling long distance flights. Lipid stores of birds during migration are composed of mostly unsaturated fatty acids; whether such a fatty acid composition enhances exercise performance of birds is unknown. We tested this hypothesis by measuring metabolic rate at rest and during intense exercise in two groups of red-eyed vireos, a long-distance migratory passerine, fed either a diet containing 82% unsaturated fat (82%U), or one containing 58% unsaturated fat (58%U). Vireos fed the 82%U diet had fat stores containing (77%) unsaturated fatty acids, whereas vireos fed the …

Ab Initio : A New Concept In Engineering Education, A History Of The Design, Creation And Implementation Of A New School Of Engineering In Richmond, Virginia (1990-2000), Henry A. Mcgee Jr.

VCU University History Books

Dr. Henry A. McGee, Jr., Founding Dean Emeritus of the School of Engineering at Virginia Commonwealth University, chronicles the history of the School of Engineering through his term as Founding Dean, 1994–1999. McGee details the process of creating a program aimed to balance innovation and entrepreneurship.

Front Matter (Pdf), North American Bird Bander

North American Bird Bander

No abstract provided.

Front Matter (Pdf), North American Bird Bander

North American Bird Bander

No abstract provided.

Dean Lindsey Cowen Business Law Lecture: Justified Monopolies: Regulating Pharmaceuticals And Telecommunications, Richard A. Epstein

Case Western Reserve Law Review

No abstract provided.

Undergraduate Catalog 2005-2006, University Of North Florida

UNF Course Catalogs

No abstract provided.

An Experimental Study Of Substrate Selection In American Toad (Bufo Americanus) Metamorphs, Geoffrey R. Smith

Faculty Publications

No abstract provided.

Survivorship Of Xenosaurus Newmanorum (Sauria: Xenosauridae) From A Seasonal Tropical Environment In Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, R. E. Ballinger

Faculty Publications

No abstract provided.

Judicial Triage: Reflections On The Debate Over Unpublished Opinions, Mitu Gulati, David C. Vladeck

Faculty Scholarship

No abstract provided.

State Of The Fisheries Report 2003/04, J. W. Penn, W. J. Fletcher, F. Head

Status Reports of the Fisheries and Aquatic Resources

The State ofthe Fisheries Report is published annually to provide an additional level of detailed reporting of the management of fish stocks and their environment undertaken by the Department of Fisheries. A summary report from the document is included in the Department's Annual Report to Parliament, which includes the Department's non-financial (fishery) performance indicators.

By summarising management changes, compliance activities and research data including stock assessments and breeding stock levels, this document provides a valuable reference point for Western Australian fisheries of major importance to the commercial and recreational sectors, and the developing aquaculture sector.

This year's State of the …

The Presence Of Plasmodium Falciparum Gametocytes In Human Blood Increases The Gravidity Of Anopheles Gambiae Mosquitoes, Heather M. Ferguson, Louis C. Gouagna, Peter Obare, Andrew F. Read, Hamza Babiker, John Githure, John C. Beier

All Peer-Reviewed Publications

We conducted a field study in an area of endemic malaria transmission in western Kenya to determine whether mosquitoes that feed on gametocyte-infected blood but do not become infected have reduced or enhanced fecundity in comparison to mosquitoes fed on uninfected blood. Fifteen paired membrane-feeding experiments were conducted in which two strains of Anopheles gambiae mosquitoes were simultaneously fed on either Plasmodium falciparum-infected blood from children or uninfected control blood from adults. The presence of noninfecting gametocytes in blood increased the probability that An. gambiae would produce eggs after one blood meal by sixfold (odds ratio for control relative to …

Prime-Boost Vaccination With Plasmid And Adenovirus Gene Vaccines Control Her2/Neu+ Metastatic Breast Cancer In Mice, Xiaoyan Wang, Jian-Ping Wang, Xiao-Mei Rao, Janet E Price, Heshan S Zhou, Lawrence B Lachman

Faculty, Staff and Student Publications

INTRODUCTION: Once metastasis has occurred, the possibility of completely curing breast cancer is unlikely, particularly for the 30 to 40% of cancers overexpressing the gene for HER2/neu. A vaccine targeting p185, the protein product of the HER2/neu gene, could have therapeutic application by controlling the growth and metastasis of highly aggressive HER2/neu+ cells. The purpose of this study was to determine the effectiveness of two gene vaccines targeting HER2/neu in preventive and therapeutic tumor models.

METHODS: The mouse breast cancer cell line A2L2, which expresses the gene for rat HER2/neu and hence p185, was injected into the mammary fat pad …

An Examination Of Ethical Issues Pertaining To Educational Research, Greg Gallagher

Level 3

The social sciences in general and educational researchers in particular have become more and more conscious of ethical propriety and the need for universally acceptable codes of ethical conduct in recent years. This newfound interest stems in part from criticisms of innovative contemporary research methodologies, and the fear that they may be at odds with certain fundamental ethical principles. This, in turn, has resulted in the integrity and validity of some of these new contemporary styles of research being held up to scrutiny and debated by adherents to the more conventional research methodologies.

This paper begins by tracing back to …

The Effect Of Red Blood Cell Velocity On Oxygenation Measurements Using Resonance Raman Spectroscopy, Derrick Williams

Theses and Dissertations

Resonance Raman spectroscopy can be used to estimate the hemoglobin oxygen saturation. Previous studies have demonstrated that exposure of oxygenated red blood cells to laser illumination may result in photo-induced displacement of oxygen from hemoglobin. In this study, an in vitro model was used to evaluate the relationship between this photo-induced effect and the red blood cell velocity. A computer-controlled system was implemented to acquire variables such as red cell velocity, microvessel diameter and hemoglobin oxygen saturation at multiple sites in selected microvascular networks. Using this system, resonance Raman spectroscopy was employed to measure hemoglobin oxygen saturation gradients in arterioles …

Codes Of Interaction, Timothy Michael Martin

Theses and Dissertations

The ideas within this thesis are meant to clarify my explorations, research and painting practice during my studies at Virginia Commonwealth University. I expand on my general statements about being fascinated by advancing technologies and concerned about the after effects of these advancements. The writing explores my curiosity about the internal, skeletal structure of things and how they operate. I explain how the paintings are idiosyncratic hybrids that evoke animation, imaginary scientific propositions, blueprints, maps, and advancing technologies. The work combines these interests with my observations of day-to-day experiences. Isolated events provide found compositions which I then manipulate: a seemingly …