Digital Commons Network^™

Qsar Study Of Skin Sensitization Using Local Lymph Node Assay Data, Adam Fedorowicz, Lingyi Zheng, Harshinder Singh, Eugene Demchuk

Faculty & Staff Scholarship

Allergic Contact Dermatitis (ACD) is a common work-related skin disease that often develops as a result of repetitive skin exposures to a sensitizing chemical agent. A variety of experimental tests have been suggested to assess the skin sensitization potential. We applied a method of Quantitative Structure-Activity Relationship (QSAR) to relate measured and calculated physical-chemical properties of chemical compounds to their sensitization potential. Using statistical methods, each of these properties, called molecular descriptors, was tested for its propensity to predict the sensitization potential. A few of the most informative descriptors were subsequently selected to build a model of skin sensitization. In …

Electrostatic Potential On Human Leukocyte Antigen: Implications For Putative Mechanism Of Chronic Beryllium Disease., James A. Snyder, Ainsley Weston, Sally S. Tinkle, Eugene Demchuk

Faculty & Staff Scholarship

The pathobiology of chronic beryllium disease (CBD) involves the major histocompatibility complex class II human leukocyte antigen (HLA). Although occupational exposure to beryllium is the cause of CBD, molecular epidemiologic studies suggest that specific (Italic)HLA-DPB1(/Italic) alleles may be genetic susceptibility factors. We have studied three-dimensional structural models of HLA-DP proteins encoded by these genes. The extracellular domains of HLA-DPA1*0103/B1*1701, *1901, *0201, and *0401, and HLA-DPA1*0201/B1*1701, *1901, *0201, and *0401 were modeled from the X-ray coordinates of an HLA-DR template. Using these models, the electrostatic potential at the molecular surface of each HLA-DP was calculated and compared. These comparisons identify specific …

Koinonia, Jim Mccormick, Lisa Burch, Stuart C. Lord, Jenny Collins, Tracy Balzer, Steve Austin, Todd Ream, Skip Trudeau

Koinonia

Themed Housing
Theme Houses: Getting to the Foundations of Community, Jim McCormick

A Year in the Little Yellow House, Lisa Burch

Conference Spotlight
Building Cross Cultural Community, Stuart C. Lord

Articles
Standards of Excellence in Short-Term Mission, Jenny Collins

"Follow Me": Intimacy with God Through Spiritual Direction, Tracy Balzer

Faith, Wisdom and Grace: Walt Campbell Interviews, Steve Austin

Features
The President's Corner

Editor's Disk

Thinking Theologically: Learning Communities, Todd Ream

Taylor University Catalog 2004-2005, Taylor University

Undergraduate Catalogs

The 2004-2005 academic catalog of Taylor University in Upland, Indiana.

Center For Lifelong Learning 2004-2006, Taylor University Fort Wayne

Institute of Correspondence Studies

The 2004-2006 catalog of the Center for Lifelong Learning at Taylor University Fort Wayne.

Montana Journalism Review, 2004, University Of Montana--Missoula. School Of Journalism

Montana Journalism Review

Newsroom Diversity -- A One-Man Band in Iraq -- Iraq’s long road to a free press -- Waking the Sleeping Giant -- The good, the bad, the blog -- Reflections on Libby -- Scenic Writing -- Photo Story: Montana Family Ranches -- The Accidental Editor -- End of the Bulldog Edition -- Connecting the Dots -- Politics’ Funny Side -- Eye for the Extraordinary -- Lying to the Press -- Stringing Readers Along -- Sex for Sale -- Injustice Ignored

Annual Reports Of The Town Of Gilford, New Hampshire, For The Year Ending December 31, 2003., Gilford Town Representatives

Gilford, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Occupational Therapy Program 2004, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

2004-2005 Graduate Catalog, Northern Illinois University

Course Catalogs Archives

No abstract provided.

Casco Bay Environmental Monitoring Program, Casco Bay Estuary Partnership

Publications

The goals of the Casco Bay Environmental Monitoring Program are: to measure the effectiveness of management actions and programs implemented under the Casco Bay Plan, and to provide essential information that can be used to redirect and refocus the Casco Bay Plan.

New Meadows River Watershed Management Plan, New Meadows River Watershed Project Steering Committee, Mary Gilbertson, Anne Hayden

Publications

No abstract provided.

Attoc159 Is A Selective Transit Peptide Receptor For The Import Of Nucleus-Encoded Chloroplast Proteins, Matthew D. Smith, Caleb M. Rounds, Fei Wang, Kunhua Chen, Meshack Afitlhile, Danny J. Schnell

Biology Faculty Publications

The members of the Toc159 family of GTPases act as the primary receptors for the import of nucleus-encoded preproteins into plastids. Toc159, the most abundant member of this family in chloroplasts, is required for chloroplast biogenesis (Bauer, J., K. Chen, A. Hiltbrunner, E. Wehrli, M. Eugster, D. Schnell, and F. Kesller, 2000, Nature, 403: 203-207) and has been shown to covalently cross-link to bound preproteins at the chloroplast surface (Ma, Y., A. Kouranov, S. LaSala, and D.J. Schnell, 1996, J. Cell Biol. 134: 1-13; Perry, S.E., and K. Keegstra, 1994, Plant Cell. 6: 93-105). These reports led to the …

America's Struggle To Develop A Consistent Legal Approach To Controversial Human Embryonic Stem Cell Research And Therapeutic Cloning: Are The Politics Getting In The Way Of Hope?, Melissa S. Burchell

Syracuse Journal of International Law and Commerce

Part I of this note evaluates human embryonic stem cell research, including an explanation of the potential benefits of this procedure and the ethical debates surrounding this type of research. Part I also identifies the legal approach to human embryonic stem cell research currently used in the U.S. Next, Part I addresses therapeutic cloning. First, therapeutic cloning is explained and then distinguished from reproductive cloning. Second, Part I discusses the ethical concerns that arise from therapeutic cloning. Third, Part I outlines the current U.S. legal approach to therapeutic cloning. Part II of this note explains the British approach to both …

Alumni Journal, Donald C. Doerr, Kate Gaetano, Samantha Whitehorne, David Marc, Tanya Fletcher, Margaret Costello, Cori Bolger

Syracuse University Magazine

No abstract provided.

Sedimentology And Geochemistry Of An Urban Coastal Lake System: Coombabah Lake Nature Reserve, Gold Coast, Queensland, Tracy D. Frank, Christopher R. Fielding

Department of Earth and Atmospheric Sciences: Faculty Publications

A study was initiated to address environmental concerns associated with changes in land use in the catchment area of Coombabah Lake, a brackish coastal lake system located in southeast Queensland. Sedimentological and geochemical data derived from a series of cores that penetrate the ca. 0–6000 year-old lacustrine sequence indicate that throughout much of its history, Coombabah Lake has remained a quiet, shallow, water body fed by fine-grained sediment dropped from suspension. Discrete and laterally continuous, shelly horizons form the basis for the stratigraphy developed for the lake sequence. A lithological transition in the upper 50 cm of the sediment column, …

The Quality Of Learners' Knowledge About Teaching And Learning, Helen Askell-Williams

Shannon Research Press

The aim of this monograph is to report the development and application of a framework for identifying quality in teachers' and learners' knowledge about teaching and learning.

Research Experience For Undergraduates Program, 2004, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Research Experience for Undergraduates

"Supported by the National Science Foundation."

Opposing Force Operations, United States Army

United States Army: Field Manuals

Opposing Force Operations, United States Army Field Manual FM 7-100.1

A Docking Score Function For Estimating Ligand-Protein Interactions: Application To Acetylcholinesterase Inhibition, Jianxin Guo, Margaret M. Hurley, Jeffery B. Wright, Gerald H. Lushington

United States Army: Publications

Acetylcholinesterase (AChE) inhibition is an important research topic because of its wide range of associated health implications. A receptor-specific scoring function was developed herein for predicting binding affinities for human AChE (huAChE) inhibitors. This method entails a statistically trained weighted sum of electrostatic and van der Waals (VDW) interactions between ligands and the receptor residues. Within the 53 ligand training set, a strong correlation was found (R² = 0.89) between computed and experimental inhibition constants. Leave-oneout cross-validation indicated high predictive power (Q² = 0.72), and analysis of a separate 16-compound test set also produced very good correlation with …

Insights- February 2004, Erika Malek

Insights

No abstract provided.

Risk Management Criteria For Metals At Blm Mining Sites, Karl L. Ford

United States Bureau of Land Management: Staff Publications

This report sets forth acceptable soil and sediment criteria for heavy metals released from abandoned hard rock mining sites as they relate to ecosystem management and protection of human health and wildlife. The USDI Bureau of Land Management (BLM) manages approximately 270 million acres of public lands, primarily in the Western U.S. These lands include several hundred thousand abandoned mining sites, some of which may be releasing heavy metals into the environment at levels toxic to wildlife.

Eos Spheres, Vol. 3, Issue 3 (Fall 2004), University Of New Hampshire. Institute For The Study Of Earth, Oceans And Space

EOS Spheres

Newsletter of the Institute for the Study of Earth, Oceans, and Space, at the University of New Hampshire.

Surfo Technical Report No. 2005-01, Surfo

SURFO Technical Reports

The 2004 technical reports written by undergraduate students participating in the SURFO (Summer Undergraduate Research Fellowships in Oceanography) Program while at the University of Rhode Island.

Pooled And Individual Bycatch Quotas: Exploring Tradeoffs Between Observer Coverage Levels, Bycatch Frequency, Pool Size, And The Precision Of Bycatch Estimates, Landon S. Jensen, Joe Koebbe, Keith R. Criddle

Economic Research Institute Study Papers

The North Pacific Ocean is highly productive, hosting many of the world's largest groundfish populations and supporting a thriving fishing industry. Numerous regulations have been implemented to control the incidental take of non-target bycatch. Individual and Pooled Bycatch Quotas have recently been proposed as instruments that could further encourage the avoidance of such bycatch and increase enforceability of by catch caps at less-than-entire-fishery levels of operation. The recent advent of fishing cooperatives such as the Pacific Whiting Conservation Cooperative and the Pollock Conservation Cooperatives create an additional impetus for examining the characteristics of pool and vessel specific bycatch quotas. We …

The Equivalence Of Evolutionary Games And Distributed Monte Carlo Learning, Yuya Sasaki

Economic Research Institute Study Papers

This paper presents a tight relationship between evolutionary game theory and distributed intelligence models. After reviewing some existing theories of replicator dynamics and distributed Monte Carlo learning, we make fonnulations and proofs of the equivalence between these two models. The relationship will be revealed not only from a theoretical viewpoint, but also by experimental simulations of the models by taking a simple symmetric zero-sum game as an example. As a consequence, it will be verified that seemingly chaotic macro dynamics generated by distributed micro-decisions can be explained with theoretical models.

An Economic Analysis Of The Pacific Halibut Commercial Fishery, Keith R. Criddle, Mark Herrmann

Economic Research Institute Study Papers

No abstract provided.

New Hampshire General Court, Journal Of The House Of Representatives, Containing The 2004 Session January 5, 2004 Through June 17, 2004., New Hampshire. General Court. House Of Representatives

Journals of the Senate and the House of Representatives of NH

Titles and imprints vary; Some volumes include miscellaneous state documents and reports; "Rules" of the House of Representatives

Dentalgram - Vol. 18, No. 01, Loma Linda University School Of Dentistry

Dentalgram

In this issue:

• Kathleen Moore named assistant dean
• New appointments
• Alumni Student Convention, 2004
• Department news
• Early selection program agreement with Antillean Adventist University
• Dean's List for autumn quarter
• In memoriam - Erwin A. McDonald, SD'61

The Thomistic Cosmological Argument, W. David Beck

SOR Faculty Publications and Presentations

No abstract provided.

Do Moms And Dads Matter? Evidence From The Social Sciences On Family Structure And The Best Interests Of The Child, Maggie Gallagher, Joshua K. Baker

University of Maryland Law Journal of Race, Religion, Gender and Class

No abstract provided.