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Pharmacotherapies Of Addiction, Naseem A. Qureshi, Tariq A. Al-Habeeb, Yaseer S. Al-Ghamdy

Neurosciences

OBJECTIVE: Millions of drug addicts worldwide require proper treatment together with good quality care. This article aims to critically review the psychopharmacology of drug addictions. METHODS: MEDLINE was systematically searched for studies describing drug treatment of addictions. Numerous studies were obtained and grouped according to the drug used to treat addictions. RESULTS: Although there are many effective antiaddictive drugs in the therapeutic armamentarium of drug addictions, a great number of patients tend to develop poor drug compliance, multiple relapses, and continue to suffer from chronic addictions coupled with negative biopsychosocial consequences. CONCLUSION: Aside from enhancing the public awareness of the …

Momentum, October 2003, Population Council

Momentum

No abstract provided.

Biodefense: Who's In Charge?, Victoria Sutton

Health Matrix: The Journal of Law-Medicine

No abstract provided.

Am I Too Fat? Bulimia As An Epidemic, Christopher Kribs, Beverly Gonzalez, Emilia Huerta-Sanchez, Angela Ortiz-Nieves, Terannie Vazquez-Alvarez

Mathematics Faculty Publications - Archive

For at least the past ten years, eating disorders have had a major impact in the physical and mental health of women, particularly young women. Anorexia and bulimia nervosa are closely linked eating disorders. Anorexia often precedes bulimia. However, there are about 2 million women in college that have been exclusively bulimic. In this article, we focus on the role of college-peer pressure on the dynamics of anorexia-free bulimia. The model looks at bulimia as a progressive disease and explores the impact of intervention (treatment) at two stages of disease progression. The impact of relapse (a common occurrence among bulimics) …

Structural Analyses Of Phycodnaviridae And Iridoviridae, Alan A. Simpson, Narayanasamy Nandhagopal, James L. Van Etten, Michael G. Rossmann

Nebraska Center for Virology: Faculty Publications

The Phycodnaviridae, Iridoviridae and related viruses, with diameters of 1500±2000 A Ê , are formed from large trigonal arrays of hexagonally close-packed capsomers forming the faces of icosahedra [Yan et al. (2000), Nature Struct. Biol. 7, 101-103; Nandhagopal et al. (2002), Proc. Natl Acad. Sci. USA, 99, 14758-14763]. Caspar and Klug predicted that such structures could be assembled from hexameric capsomers [Caspar & Klug (1962), Cold Spring Harbor. Symp. Quant. Biol. 27, 1-24], as was subsequently found in numerous icosahedral viruses. During the course of evolution, some viruses, including the virus families …

G03-1513 Understanding Fungal (Mold) Toxins (Mycotoxins), Michael P. Carlson, Steveb M. Ensley

University of Nebraska-Lincoln Extension: Historical Materials

Mycotoxins are chemicals produced by fungi (molds) under certain conditions. They are not essential for fungal growth or reproduction, and are toxic to animals or humans.

This NebGuide briefly discusses mycotoxins commonly encountered in grains and feeds used in Nebraska and the mycotoxicoses they cause. Mycotoxin sources and clinical signs, lesions, diagnostic aids and treatment for each mycotoxicosis are listed.

Scale-Up Of The Fermentation And Purification Of The Recombinant Heavy Chain Fragment C Of Botulinum Neurotoxin Serotype F, Expressed In Pichia Pastoris, Scott K. Johnson, Wenhui Zhang, Leonard A. Smith, Karen J. Hywood-Potter, S. Todd Swanson, Vicki L. Schlegel, Michael M. Meagher

Michael Meagher Publications

A recombinant heavy chain fragment C of botulinum neurotoxin serotype F (BoNTF(Hc)) has been expressed in Pichia pastoris for use as an antigen in a proposed human vaccine. P. pastoris cells were grown using glycerol batch, glycerol fed-batch, and methanol fedbatch methods to achieve high cell densities. The total cellular protein recovered after homogenization was 72 mg/g of cell paste. BoNTF(Hc) was purified from soluble Pichia cell lysate employing ion-exchange chromatographic (IEC) and hydrophobic interaction chromatographic (HIC) methods developed at the bench scale using 10–100mL columns. The process was performed at the pilot scale using 1–4 L columns for evaluation …

Depression: Clinical Definition And Case Histories, Manuel Garcia Barroso

International Journal of Transpersonal Studies

NA

Black Vultures Feeding On Vegetables And Tortoise Dung, Eric D. Stolen

Florida Field Naturalist

No abstract provided.

Am I My Brother's Keeper: Disabilities, Paternalism, And Threats To Self, D. Aaron Lacy

Santa Clara Law Review

No abstract provided.

Uri Undergraduate And Graduate Course Catalog 2003-2004, University Of Rhode Island

URI Course Catalogs Archive

This is a digitized, downloadable version of the University of Rhode Island course catalog.

Coastal Versus Inland Shorebird Species: Interlinked Fundamental Dichotomies Between Their Life- And Demographic Histories?, Theunis Piersma

Wader Study Group Bulletin

No abstract provided.

Yrg Care Base Model Report: Integrated Prevention, Care, And Support Services, Christopher Castle

HIV and AIDS

In September 1999, YRG CARE embarked on a research project in collaboration with the Horizons Program and the International HIV/AIDS Alliance entitled “Scaling Up Affordable and Appropriate Care and Support Services for People Living with HIV/AIDS in South India.” The study aims to better understand the affordability and appropriateness of an integrated care and support model in an emerging epidemic situation to meet the needs of people living with HIV/AIDS (PLHA) and improve their quality of life. A second aim is to examine the process and costs of scaling up this model. A critical step toward achieving both goals is …

Ending Child Labor: A Role For International Human Rights Law?, James J. Silk, Meron Makonnen

Saint Louis University Public Law Review

No abstract provided.

Age, Temperature, And Parasitaemia Predict Chloroquine Treatment Failure And Anaemia In Children With Uncomplicated Plasmodium Falciparum Malaria, D.H. Hamer, W.B. Macleod, E. Addo-Yobo, C.P Duggan, B. Estrella, W.W. Fawzi, J.K. Konde-Lule, V. Mwanakasale, Zul Premji, F. Sempertegui, F.P. Ssengooba, K. Yeboah-Antwi, J.L. Simon

Pathology, East Africa

The prevalence of chloroquine-resistant Plasmodium falciparum malaria has been increasing in sub-Saharan Africa and parts of South America over the last 2 decades, and has been associated with increased anaemia-associated morbidity and higher mortality rates. Prospectively collected clinical and parasitological data from a multicentre study of 788 children aged 6-59 months with uncomplicated P. falciparum malaria were analysed in order to identify risk factors for chloroquine treatment failure and to assess its impact on anaemia after therapy. The proportion of chloroquine treatment failures (combined early and late treatment failures) was higher in the central-eastern African countries (Tanzania, 53%; Uganda, 80%; …

Community-Level Hiv Prevention Intervention: The Effects Of Gay Men's Health Retreats, Rigmor Berg Carneiro

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.

Isovolumetric Regulation In Mammal Cells: Role Of Taurine, B. Ordaz, R. Franco, National University Of Mexico Tuz

School of Veterinary and Biomedical Sciences: Faculty Publications

The ability to regulate cell volume is an ancient conserved trait present in essentially all species through evolution. The maintenance of a constant cell volume is a homeostatic imperative in animal cells. Changes in cell water content affecting the concentration of intracellular messenger molecules impair the complex signaling network, crucial for cell functioning and intercellular communication. Although the renal homeostatic mechanisms exert a precise control of extracellular fluid osmolarity, this is challenged in a variety of pathological situations. The intracellular volume constancy is continuously compromised by the generation of local and transient osmotic microgradients, associated with nutrients uptake, secretion, cytoskeleton …

Plasma Membrane Topology Of Syncytial Domains Of Herpes Simplex Virus Type 1 Glycoprotein K (Gk): The Ul20 Protein Enables Cell Surface Localization Of Gk But Not Gk-Mediated Cell-To-Cell Fusion, Timothy P. Foster, Xavier Alvarez, Konstantin G. Kousoulas

Faculty Publications

Most spontaneously occurring mutations that cause extensive herpes simplex virus type 1 (HSV-1)-induced cell fusion are single amino acid changes within glycoprotein K (gK). Despite the strong genetic association of gK with virus-induced cell fusion, its direct involvement in cellular membrane fusion has been controversial, largely due to previously unsuccessful efforts to detect gK expression on virion and cellular surfaces. Recently, we showed that gK is expressed on HSV-1 virions and functioned in virus entry (T. P. Foster, G. V. Rybachuk, and K. G. Kousoulas, J. Virol. 75:12431-12438, 2001). To determine whether gK is expressed on cellular surfaces, as well …

Natural Bovine Lentiviral Type 1 Infection In Holstein Dairy Cattle. I. Clinical, Serological, And Pathological Observations, T. G. Snider, B. F. Jenny, P. G. Hoyt, K. S. Coats, K. F. Graves, C. R. Cooper, R. W. Storts, D. G. Luther

Faculty Publications

Clinical, serological, and pathological abnormalities observed in Holstein cows naturally infected with bovine lentivirus 1 bovine immunodeficiency virus (BIV) and other infections were progressive and most commonly associated with weight loss, lymphoid system deficiency, and behavioral changes. Clinical evidence of meningoencephalitis was dullness, stupor, and occasional head or nose pressing postures. The polymerase chain reactions associated the BIV provirus with the lesions in the central nervous system and lymphoid tissues. Multiple concurrent infections developed in retrovirally infected cows undergoing normal stresses associated with parturition and lactation. A major functional correlate of the lymphoreticular alterations was the development of multiple secondary …

A Look At Climate Change And The Evolution Of The Kyoto Protocol, Todd M. Lopez

Natural Resources Journal

No abstract provided.

Looking Backward: The Twentieth Century Revolutions In Psychiatry, Law And Public Mental Health, Sheldon Gelman

Law Faculty Articles and Essays

Do histories of psychiatry make a difference--or have legal implications--in the present? Does our current situation help explain what historians say about psychiatry's past? Focusing on the past half century--the era of medications-- this paper explores the reciprocal relationship between the present and the past in psychiatry. Part II sketches the medical developments that constitute the subjects of any history of psychiatry. This Part also examines related developments in law. Part III introduces some problems of psychiatric historiography and examines some historians' attempts to deal with them. Part IV analyzes the account of psychiatry's past contained in Edward Shorter's well-regarded …

Chronic Wasting Disease In Deer And Elk: A Critique Of Current Models And Their Application, Eric M. Schauber, Alan Woolf

Publications

Chronic wasting disease (CWD), a fatal transmissible spongiform encephalopathy of deer (Odocoileus spp.) and elk (Cervus elaphus), presents a challenge to wildlife managers because little is known about its transmission, yet it could severely threaten wildlife populations if action is not taken rapidly. Published mathematical models predict that CWD could devastate populations of free-living deer and elk, prompting wildlife managers to attempt large-scale eradication of deer in hopes of containing CWD outbreaks. Our objective is to critically examine the theoretical and empirical support for current models of CWD epizootiology, in light of herd health-management actions. We identify …

A Method For Testing Low-Value Spatial Clustering For Rare Diseases, Ge Lin, Tonglin Zhang

Regional Research Institute Working Papers

This paper proposes a method that tests for the existence of low-value spatial clustering while accounting for the influence of high-value clustering. Although the method was developed in reference to the Tango test, it can be extended to other testing methods. The simulation results showed that the proposed method is able to effectively detect low-value clustering with substantially lower rates of type I errors than those of the Tango test, while maintaining comparable statistical power. Applying the method in a case study of leukemia in Minnesota demonstrated an overall tendency toward low-value clustering of leukemia mortality for males but provided …

Annual Report On Research Activities 2002-2003, Lingnan University (Hong Kong, China)

Annual Report on Research Activities to Research Grants Council

No abstract provided.

Excellence In Clinical Practice [Complete Issue - Digital Origin : Fourth Quarter 2003, Vol. 4, 4], Sigma Theta Tau International

Sigma Past Publishing - Excellence Newsletters

Publishing History: Nursing Excellence published yearly in 1998 and 1999. The publication became Excellence in the first quarter 2000. It transitioned to Excellence in Nursing Education, Excellence in Nursing Administration, and Excellence in Clinical Practice in the second quarter 2000 with volume 1, number 2. Excellence in Nursing Education transitioned to Excellence in Nursing Education & Research in the first quarter 2002.

Publishing Frequency: Yearly 1998, 1999; Quarterly 2000 - 2004.

Format: Print 1999 - third quarter 2002; Online fourth quarter 2002 - first quarter 2004. Ceased publishing in 2004.

Select features in this issue:

Kids at school. Nurses at …

The Duty To “Expect The Unexpected”: Mitigating Extreme Natural Threats To The Global Commons Such As Asteroid Impacts With The Earth, Evan R. Seamone

Journal Articles

This Article develops a framework to govern the interactions of nations cooperating to mitigate the threat of unexpected natural disasters that potentially could affect them all. It uses asteroid impact with the Earth as the representative example because this is an "unusual and extreme" disaster that has created difficulty for lawmakers due to its many unanswerable questions. By explaining a number of the legal requirements necessary to mitigate such threats, this Article identifies legal principles that apply equally to natural threats throughout the global commons. The law involved in this analysis arises, in great part, from the judicial recognition of …

Quarantine Redux: Bioterrorism, Aids And The Curtailment Of Individual Liberty In The Name Of Public Health, Wendy E. Parmet

Health Matrix: The Journal of Law-Medicine

No abstract provided.

Florida's Scarlet Letter Repealed: A Retrospective Analysis Of The Constitutionality Of The Florida Adoption Notification Provision And A Commentary On The Future Of The Right To Privacy, Nicholas Ciappetta

Hofstra Law Review

No abstract provided.

Racism Or Realpolitik? U.S. Foreign Policy And The Hiv/Aids Catastrophe In Sub-Saharan Africa, David P. Fidler

Articles by Maurer Faculty

No abstract provided.

Biol 495.80: From The Black Death To Aids, The Cultural And Scientific Impact Of Plagues, Herbert M. Swick

University of Montana Course Syllabi

No abstract provided.