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Articles 1231 - 1260 of 3985
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Thiol Isomerase Erp57 Targets And Modulates The Lectin Pathway Of Complement Activation, Oskar Eriksson, Joyce Chiu, Philip J. Hogg, John P. Atkinson, M. Kathryn Liszewski, Robert Flaumenhaft, Bruce Furie
Thiol Isomerase Erp57 Targets And Modulates The Lectin Pathway Of Complement Activation, Oskar Eriksson, Joyce Chiu, Philip J. Hogg, John P. Atkinson, M. Kathryn Liszewski, Robert Flaumenhaft, Bruce Furie
Open Access Publications
No abstract provided.
Photoreceptors In A Mouse Model Of Leigh Syndrome Are Capable Of Normal Light-Evoked Signaling, Sidney M. Gospe Iii, Amanda M. Travis, Alexander V. Kolesnikov, Mikael Klingeborn, Luyu Wang, Vladimir J. Kefalov, Vadim Y. Arshavsky
Photoreceptors In A Mouse Model Of Leigh Syndrome Are Capable Of Normal Light-Evoked Signaling, Sidney M. Gospe Iii, Amanda M. Travis, Alexander V. Kolesnikov, Mikael Klingeborn, Luyu Wang, Vladimir J. Kefalov, Vadim Y. Arshavsky
Open Access Publications
No abstract provided.
Nfat5 Up-Regulates Expression Of The Kidney-Specific Ubiquitin Ligase Gene Rnf183 Under Hypertonic Conditions In Inner-Medullary Collecting Duct Cells, Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, Masayuki Kaneko
Nfat5 Up-Regulates Expression Of The Kidney-Specific Ubiquitin Ligase Gene Rnf183 Under Hypertonic Conditions In Inner-Medullary Collecting Duct Cells, Yujiro Maeoka, Yan Wu, Takumi Okamoto, Soshi Kanemoto, Xiao Peng Guo, Atsushi Saito, Rie Asada, Koji Matsuhisa, Takao Masaki, Kazunori Imaizumi, Masayuki Kaneko
Open Access Publications
No abstract provided.
A Stable Tetramer Is Not The Only Oligomeric State That Mitochondrial Single-Stranded Dna Binding Proteins Can Adopt, Saurabh P. Singh, Vandna Kukshal, Roberto Galletto
A Stable Tetramer Is Not The Only Oligomeric State That Mitochondrial Single-Stranded Dna Binding Proteins Can Adopt, Saurabh P. Singh, Vandna Kukshal, Roberto Galletto
Open Access Publications
No abstract provided.
The Structure Of Acinetobacter-Secreted Protease Cpaa Complexed With Its Chaperone Cpab Reveals A Novel Mode Of A T2ss Chaperone–Substrate Interaction, Darya V. Urusova, Rachel L. Kinsella, Nichole D. Salinas, M. Florencia Haurat, Mario F. Feldman, Niraj H. Tolia
The Structure Of Acinetobacter-Secreted Protease Cpaa Complexed With Its Chaperone Cpab Reveals A Novel Mode Of A T2ss Chaperone–Substrate Interaction, Darya V. Urusova, Rachel L. Kinsella, Nichole D. Salinas, M. Florencia Haurat, Mario F. Feldman, Niraj H. Tolia
Open Access Publications
No abstract provided.
Association Between The Hla-Drb1*03:01-Dqb1*02:01 Haplotype And Pf4/Heparin Antibodies, Ray Zhang, Brian F. Duffy, Vinzenz Lange, Charles S. Eby, Chang Liu
Association Between The Hla-Drb1*03:01-Dqb1*02:01 Haplotype And Pf4/Heparin Antibodies, Ray Zhang, Brian F. Duffy, Vinzenz Lange, Charles S. Eby, Chang Liu
Open Access Publications
No abstract provided.
Hepatic Monoacylglycerol Acyltransferase 1 Is Induced By Prolonged Food Deprivation To Modulate The Hepatic Fasting Response, Andrew J. Lutkewitte, Kyle S. Mccommis, George G. Schweitzer, Kari T. Chambers, Mark J. Graham, Lingjue Wang, Gary J. Patti, Angela M. Hall, Brian N. Finck
Hepatic Monoacylglycerol Acyltransferase 1 Is Induced By Prolonged Food Deprivation To Modulate The Hepatic Fasting Response, Andrew J. Lutkewitte, Kyle S. Mccommis, George G. Schweitzer, Kari T. Chambers, Mark J. Graham, Lingjue Wang, Gary J. Patti, Angela M. Hall, Brian N. Finck
Open Access Publications
No abstract provided.
An Overview Of Mechanical Circulatory Support In Single-Ventricle Patients, Jacob R Miller, Timothy S Lancaster, Connor Callahan, Aaron M Abarbanell, Pirooz Eghtesady
An Overview Of Mechanical Circulatory Support In Single-Ventricle Patients, Jacob R Miller, Timothy S Lancaster, Connor Callahan, Aaron M Abarbanell, Pirooz Eghtesady
Open Access Publications
The population of people with a single-ventricle is continually increasing due to improvements across the spectrum of medical care. Unfortunately, a proportion of these patients will develop heart failure. Often, for these patients, mechanical circulatory support (MCS) represents the only available treatment option. While single-ventricle patients currently represent a small proportion of the total number of patients who receive MCS, as the single-ventricle patient population increases, this number will increase as well. Outcomes for these complex single-ventricle patients who require MCS has begun to be evaluated. When considering the entire population, survival to hospital discharge is 30-50%, though this must …
Insulin-Independent Reversal Of Type-1 Diabetes Following Transplantation Of Adult Brown Adipose Tissue Supplemented With Igf-1, Subhadra C. Gunawardana, David W. Piston
Insulin-Independent Reversal Of Type-1 Diabetes Following Transplantation Of Adult Brown Adipose Tissue Supplemented With Igf-1, Subhadra C. Gunawardana, David W. Piston
Open Access Publications
No abstract provided.
High-Density Speckle Contrast Optical Tomography Of Cerebral Blood Flow Response To Functional Stimuli In The Rodent Brain, Tanja Dragojević, Ernesto E. Vidal Rosas, Joseph L. Hollmann, Joseph P. Culver, Carles Justicia, Turgut Durduran
High-Density Speckle Contrast Optical Tomography Of Cerebral Blood Flow Response To Functional Stimuli In The Rodent Brain, Tanja Dragojević, Ernesto E. Vidal Rosas, Joseph L. Hollmann, Joseph P. Culver, Carles Justicia, Turgut Durduran
Open Access Publications
No abstract provided.
Visual Field Loss In Patients With Diabetes In The Absence Of Clinically-Detectable Vascular Retinopathy In A Nationally Representative Survey, Yicheng K. Bao, Yan Yan, Mae Gordon, Janet B. Mcgill, Michael Kass, Rithwick Rajagopal
Visual Field Loss In Patients With Diabetes In The Absence Of Clinically-Detectable Vascular Retinopathy In A Nationally Representative Survey, Yicheng K. Bao, Yan Yan, Mae Gordon, Janet B. Mcgill, Michael Kass, Rithwick Rajagopal
Open Access Publications
No abstract provided.
Graft Immaturity And Safety Concerns In Transplanted Human Kidney Organoids, Sun Ah Nam, Kohei Uchimura, Benjamin D. Humphreys, Et Al.
Graft Immaturity And Safety Concerns In Transplanted Human Kidney Organoids, Sun Ah Nam, Kohei Uchimura, Benjamin D. Humphreys, Et Al.
Open Access Publications
No abstract provided.
Two-Photon Microperimetry: Sensitivity Of Human Photoreceptors To Infrared Light, Daniel Ruminski, Grazyna Palczewska, Maciej Nowakowski, Agnieszka Zielińska, Vladimir J Kefalov, Katarzyna Komar, Krzysztof Palczewski, Maciej Wojtkowski
Two-Photon Microperimetry: Sensitivity Of Human Photoreceptors To Infrared Light, Daniel Ruminski, Grazyna Palczewska, Maciej Nowakowski, Agnieszka Zielińska, Vladimir J Kefalov, Katarzyna Komar, Krzysztof Palczewski, Maciej Wojtkowski
Open Access Publications
Microperimetry is a subjective ophthalmologic test used to assess retinal function at various specific and focal locations of the visual field. Historically, visible light has been described as ranging from 400 to 720 nm. However, we previously demonstrated that infra-red light can initiate visual transduction in rod photoreceptors by a mechanism of two-photon absorption by visual pigments. Here we introduce a newly designed and constructed two-photon microperimeter. We provide for the first time evidence of the presence of a nonlinear process occurring in the human retina based on psychophysical tests using newly developed instrumentation. Since infra-red light penetrates the aged …
Congenital Aortic Valve Stenosis, Gautam K Singh
Congenital Aortic Valve Stenosis, Gautam K Singh
Open Access Publications
Aortic valve stenosis in children is a congenital heart defect that causes fixed form of hemodynamically significant left ventricular outflow tract obstruction with progressive course. Neonates and young infants who have aortic valve stenosis, usually develop congestive heart failure. Children and adolescents who have aortic valve stenosis, are mostly asymptomatic, although they may carry a small but significant risk of sudden death. Transcatheter or surgical intervention is indicated for symptomatic patients or those with moderate to severe left ventricular outflow tract obstruction. Many may need reintervention.
Standard Operating Procedure For Somatic Variant Refinement Of Sequencing Data With Paired Tumor And Normal Samples, Erica K. Barnell, Peter Ronning, Katie M. Campbell, Kilannin Krysiak, Benjamin J. Ainscough, Lana M. Sheta, Shahil P. Pema, Alina D. Schmidt, Megan Richters, Kelsy C. Cotto, Arpad M. Danos, Cody Ramirez, Zachary L. Skidmore, Nicholas C. Spies, Jasreet Hundal, Malik S. Sediqzad, Jason Kunisaki, Felicia Gomez, Lee Trani, Matthew Matlock, Alex H. Wagner, S. Joshua Swamidass, Malachi Griffith, Obi L. Griffith
Standard Operating Procedure For Somatic Variant Refinement Of Sequencing Data With Paired Tumor And Normal Samples, Erica K. Barnell, Peter Ronning, Katie M. Campbell, Kilannin Krysiak, Benjamin J. Ainscough, Lana M. Sheta, Shahil P. Pema, Alina D. Schmidt, Megan Richters, Kelsy C. Cotto, Arpad M. Danos, Cody Ramirez, Zachary L. Skidmore, Nicholas C. Spies, Jasreet Hundal, Malik S. Sediqzad, Jason Kunisaki, Felicia Gomez, Lee Trani, Matthew Matlock, Alex H. Wagner, S. Joshua Swamidass, Malachi Griffith, Obi L. Griffith
Open Access Publications
No abstract provided.
Early Increase Of Csf Strem2 In Alzheimer's Disease Is Associated With Tau Related-Neurodegeneration But Not With Amyloid-Β Pathology, Marc Suarez-Calvet, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Et Al
Early Increase Of Csf Strem2 In Alzheimer's Disease Is Associated With Tau Related-Neurodegeneration But Not With Amyloid-Β Pathology, Marc Suarez-Calvet, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Et Al
Open Access Publications
No abstract provided.
Pcna Accelerates The Nucleotide Incorporation Rate By Dna Polymerase Δ, Tanumoy Mondol, Joseph L. Stodola, Roberto Galletto, Peter M. Burgers
Pcna Accelerates The Nucleotide Incorporation Rate By Dna Polymerase Δ, Tanumoy Mondol, Joseph L. Stodola, Roberto Galletto, Peter M. Burgers
Open Access Publications
No abstract provided.
Me-Class2 Reveals Context Dependent Regulatory Roles For 5-Hydroxymethylcytosine, Christopher E. Schlosberg, Dennis Y. Wu, Harrison W. Gabel, John R. Edwards
Me-Class2 Reveals Context Dependent Regulatory Roles For 5-Hydroxymethylcytosine, Christopher E. Schlosberg, Dennis Y. Wu, Harrison W. Gabel, John R. Edwards
Open Access Publications
No abstract provided.
Csf1r Antagonism Limits Local Restimulation Of Antiviral Cd8+ T Cells During Viral Encephalitis, Kristen E. Funk, Robyn S. Klein
Csf1r Antagonism Limits Local Restimulation Of Antiviral Cd8+ T Cells During Viral Encephalitis, Kristen E. Funk, Robyn S. Klein
Open Access Publications
No abstract provided.
Aebp1 Down Regulation Induced Cell Death Pathway Depends On Pten Status Of Glioma Cells, Swati Sinha, Arun Renganathan, Prathima B. Nagendra, Vasudeva Bhat, Brian Steve Mathew, Manchanahalli R. Satyanarayana Rao
Aebp1 Down Regulation Induced Cell Death Pathway Depends On Pten Status Of Glioma Cells, Swati Sinha, Arun Renganathan, Prathima B. Nagendra, Vasudeva Bhat, Brian Steve Mathew, Manchanahalli R. Satyanarayana Rao
Open Access Publications
No abstract provided.
Study Of Environmental Enteropathy And Malnutrition (Seem) In Pakistan: Protocols For Biopsy Based Biomarker Discovery And Validation, Najeeha T. Iqbal, Ta-Chiang Liu, Michael J. Barratt, Vanderlene L. Kung, Jeffrey I. Gordon, Et Al
Study Of Environmental Enteropathy And Malnutrition (Seem) In Pakistan: Protocols For Biopsy Based Biomarker Discovery And Validation, Najeeha T. Iqbal, Ta-Chiang Liu, Michael J. Barratt, Vanderlene L. Kung, Jeffrey I. Gordon, Et Al
Open Access Publications
No abstract provided.
Optical Resolution Photoacoustic Microscopy Of Ovary And Fallopian Tube, Bin Rao, Xiandong Leng, Yifeng Zeng, Yixiao Lin, Ruimin Chen, Qifa Zhou, Andrea R. Hagemann, Lindsay M. Kuroki, Carolyn K. Mccourt, David G. Mutch, Matthew A. Powell, Ian S. Hagemann, Quing Zhu
Optical Resolution Photoacoustic Microscopy Of Ovary And Fallopian Tube, Bin Rao, Xiandong Leng, Yifeng Zeng, Yixiao Lin, Ruimin Chen, Qifa Zhou, Andrea R. Hagemann, Lindsay M. Kuroki, Carolyn K. Mccourt, David G. Mutch, Matthew A. Powell, Ian S. Hagemann, Quing Zhu
Open Access Publications
No abstract provided.
Abcc9-Related Intellectual Disability Myopathy Syndrome Is A Katp Channelopathy With Loss-Of-Function Mutations In Abcc9, Conor Mcclenaghan, Theresa Harter, Monica Sala-Rabanal, Chris H. Emfinger, Yan Huang, Soma S. Singareddy, Colin G. Nichols, Jamie Gunn, David F. Wozniak, Attila Kovacs, Maria S. Remedi, Et Al.
Abcc9-Related Intellectual Disability Myopathy Syndrome Is A Katp Channelopathy With Loss-Of-Function Mutations In Abcc9, Conor Mcclenaghan, Theresa Harter, Monica Sala-Rabanal, Chris H. Emfinger, Yan Huang, Soma S. Singareddy, Colin G. Nichols, Jamie Gunn, David F. Wozniak, Attila Kovacs, Maria S. Remedi, Et Al.
Open Access Publications
No abstract provided.
Fast Objective Coupled Planar Illumination Microscopy, Cody J. Greer, Timothy E. Holy
Fast Objective Coupled Planar Illumination Microscopy, Cody J. Greer, Timothy E. Holy
Open Access Publications
No abstract provided.
Updated Results From The Phase 3 Helios Study Of Ibrutinib, Bendamustine, And Rituximab In Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Nancy Lee Bartlett, Et Al.
Updated Results From The Phase 3 Helios Study Of Ibrutinib, Bendamustine, And Rituximab In Relapsed Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Nancy Lee Bartlett, Et Al.
Open Access Publications
No abstract provided.
Shared Autonomic Pathways Connect Bone Marrow And Peripheral Adipose Tissues Across The Central Neuraxis, Natalie K Y Wee, Madelyn R Lorenz, Yusuf Bekirov, Mark F Jacquin, Erica L Scheller
Shared Autonomic Pathways Connect Bone Marrow And Peripheral Adipose Tissues Across The Central Neuraxis, Natalie K Y Wee, Madelyn R Lorenz, Yusuf Bekirov, Mark F Jacquin, Erica L Scheller
Open Access Publications
Bone marrow adipose tissue (BMAT) is increased in both obesity and anorexia. This is unique relative to white adipose tissue (WAT), which is generally more attuned to metabolic demand. It suggests that there may be regulatory pathways that are common to both BMAT and WAT and also those that are specific to BMAT alone. The central nervous system (CNS) is a key mediator of adipose tissue function through sympathetic adrenergic neurons. Thus, we hypothesized that central autonomic pathways may be involved in BMAT regulation. To test this, we first quantified the innervation of BMAT by tyrosine hydroxylase (TH) positive nerves …
Perturbing Cohesin Dynamics Drives Mre11 Nuclease-Dependent Replication Fork Slowing, Denisse Carvajal-Maldonado, Andrea K. Byrum, Jessica Jackson, Sarah Wessel, Delphine Lemacon, Laure Guitton-Sert, Annabel Quinet, Stephanie Tirman, Simona Graziano, Jean-Yves Masson, David Cortez, Susana Gonzalo, Nima Mosammaparast, Alessandro Vindigni
Perturbing Cohesin Dynamics Drives Mre11 Nuclease-Dependent Replication Fork Slowing, Denisse Carvajal-Maldonado, Andrea K. Byrum, Jessica Jackson, Sarah Wessel, Delphine Lemacon, Laure Guitton-Sert, Annabel Quinet, Stephanie Tirman, Simona Graziano, Jean-Yves Masson, David Cortez, Susana Gonzalo, Nima Mosammaparast, Alessandro Vindigni
Open Access Publications
No abstract provided.
Spatiotemporal Dynamics Of Multidrug Resistant Bacteria On Intensive Care Unit Surfaces, Alaric W. D'Souza, Robert F. Potter, Meghan Wallace, Angela Shupe, Sanket Patel, Xiaoqing Sun, Danish Gul, Jennie H. Kwon, Saadia Andleeb, Carey-Ann D. Burnham, Gautam Dantas
Spatiotemporal Dynamics Of Multidrug Resistant Bacteria On Intensive Care Unit Surfaces, Alaric W. D'Souza, Robert F. Potter, Meghan Wallace, Angela Shupe, Sanket Patel, Xiaoqing Sun, Danish Gul, Jennie H. Kwon, Saadia Andleeb, Carey-Ann D. Burnham, Gautam Dantas
Open Access Publications
No abstract provided.
Metabolomic Networks Connect Host-Microbiome Processes To Human Clostridioides Difficile Infections, John I. Robinson, William H. Weir, Jan R. Crowley, Tiffany Hink, Kimberly A. Reske, Jennie H. Kwon, Carey-Ann D. Burnham, Erik R. Dubberke, Peter J. Mucha, Jeffrey P. Henderson
Metabolomic Networks Connect Host-Microbiome Processes To Human Clostridioides Difficile Infections, John I. Robinson, William H. Weir, Jan R. Crowley, Tiffany Hink, Kimberly A. Reske, Jennie H. Kwon, Carey-Ann D. Burnham, Erik R. Dubberke, Peter J. Mucha, Jeffrey P. Henderson
Open Access Publications
No abstract provided.
Web-Based Prescription Opioid Abuse Prevention For Adolescents: Program Development And Formative Evaluation, Sarah K. Moore, Michael Grabinski, Sarah Bessen, Jacob T. Borodovsky, Lisa A. Marsch
Web-Based Prescription Opioid Abuse Prevention For Adolescents: Program Development And Formative Evaluation, Sarah K. Moore, Michael Grabinski, Sarah Bessen, Jacob T. Borodovsky, Lisa A. Marsch
Open Access Publications
No abstract provided.