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Resting State Functional Connectivity Predictors Of Treatment Response To Electroconvulsive Therapy In Depression, M. Moreno-Ortega, J. Prudic, S. Rowny, G. H. Patel, A. Kangarlu, S. Lee, J. Grinband, T. Palomo, T. Perera, M. F. Glasser, D. C. Javitt Jan 2019

Resting State Functional Connectivity Predictors Of Treatment Response To Electroconvulsive Therapy In Depression, M. Moreno-Ortega, J. Prudic, S. Rowny, G. H. Patel, A. Kangarlu, S. Lee, J. Grinband, T. Palomo, T. Perera, M. F. Glasser, D. C. Javitt

Open Access Publications

No abstract provided.


Chd4 Regulates The Dna Damage Response And Rad51 Expression In Glioblastoma, Lisa D. Mckenzie, John W. Leclair, Kayla N. Miller, Averey D. Strong, Hilda L. Chan, Edward L. Oates, Keith L. Ligon, Cameron W. Brennan, Milan G. Chheda Jan 2019

Chd4 Regulates The Dna Damage Response And Rad51 Expression In Glioblastoma, Lisa D. Mckenzie, John W. Leclair, Kayla N. Miller, Averey D. Strong, Hilda L. Chan, Edward L. Oates, Keith L. Ligon, Cameron W. Brennan, Milan G. Chheda

Open Access Publications

No abstract provided.


Evidence For Altered Neurodevelopment And Neurodegeneration In Wolfram Syndrome Using Longitudinal Morphometry, Heather M. Lugar, Jonathan M. Koller, Jerrel Rutlin, Sarah A. Eisenstein, Olga Neyman, Anagha Narayanan, Ling Chen, Joshua S. Shimony, Tamara Hershey Jan 2019

Evidence For Altered Neurodevelopment And Neurodegeneration In Wolfram Syndrome Using Longitudinal Morphometry, Heather M. Lugar, Jonathan M. Koller, Jerrel Rutlin, Sarah A. Eisenstein, Olga Neyman, Anagha Narayanan, Ling Chen, Joshua S. Shimony, Tamara Hershey

Open Access Publications

No abstract provided.


Hepatic Arginase 2 (Arg2) Is Sufficient To Convey The Therapeutic Metabolic Effects Of Fasting, Yiming Zhang, Cassandra B. Higgins, Hannah M. Fortune, Phillip Chen, Alicyn I. Stothard, Allyson L. Mayer, Benjamin M. Swarts, Brian J. Debosch Jan 2019

Hepatic Arginase 2 (Arg2) Is Sufficient To Convey The Therapeutic Metabolic Effects Of Fasting, Yiming Zhang, Cassandra B. Higgins, Hannah M. Fortune, Phillip Chen, Alicyn I. Stothard, Allyson L. Mayer, Benjamin M. Swarts, Brian J. Debosch

Open Access Publications

No abstract provided.


The Bin1 Rs744373 Snp Is Associated With Increased Tau-Pet Levels And Impaired Memory, N Franzmeier, A Rubinski, J Neitzel, M Ewers, John Morris, Marcus Raichle, David Holtzman, Nigel J. Cairns, Erin Householder, Lisa Taylor-Reinwald, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, Angela Oliver Jan 2019

The Bin1 Rs744373 Snp Is Associated With Increased Tau-Pet Levels And Impaired Memory, N Franzmeier, A Rubinski, J Neitzel, M Ewers, John Morris, Marcus Raichle, David Holtzman, Nigel J. Cairns, Erin Householder, Lisa Taylor-Reinwald, Beau Ances, Maria Carroll, Sue Leon, Mark A. Mintun, Stacy Schneider, Angela Oliver

Open Access Publications

No abstract provided.


Two-Year Evaluation Of Mandatory Bundled Payments For Joint Replacement, Michael L. Barnett, Andrew Wilcock, J. Michael Mcwilliams, Arnold M. Epstein, Karen E. Joynt Maddox, E. John Orav, David C. Grabowski, Ateev Mehrotra Jan 2019

Two-Year Evaluation Of Mandatory Bundled Payments For Joint Replacement, Michael L. Barnett, Andrew Wilcock, J. Michael Mcwilliams, Arnold M. Epstein, Karen E. Joynt Maddox, E. John Orav, David C. Grabowski, Ateev Mehrotra

Open Access Publications

No abstract provided.


Repetitive Concussive And Subconcussive Injury In A Human Tau Mouse Model Results In Chronic Cognitive Dysfunction And Disruption Of White Matter Tracts, But Not Tau Pathology, Mihika Gangolli, Joseph Benetatos, Thomas J. Esparza, Emeka M. Fountain, Shamilka Seneviratne, David L. Brody Jan 2019

Repetitive Concussive And Subconcussive Injury In A Human Tau Mouse Model Results In Chronic Cognitive Dysfunction And Disruption Of White Matter Tracts, But Not Tau Pathology, Mihika Gangolli, Joseph Benetatos, Thomas J. Esparza, Emeka M. Fountain, Shamilka Seneviratne, David L. Brody

Open Access Publications

No abstract provided.


Comparison Of Two Models Of Family-Based Treatment For Childhood Obesity: A Pilot Study, Kristie Bergmann, Zoe Mestre, David Strong, Dawn M. Eichen, Kyung Rhee, Scott Crow, Denise Wilfley, Kerri N. Boutelle Jan 2019

Comparison Of Two Models Of Family-Based Treatment For Childhood Obesity: A Pilot Study, Kristie Bergmann, Zoe Mestre, David Strong, Dawn M. Eichen, Kyung Rhee, Scott Crow, Denise Wilfley, Kerri N. Boutelle

Open Access Publications

No abstract provided.


Repetitive Transcranial Magnetic Stimulation With Resting-State Network Targeting For Treatment-Resistant Depression In Traumatic Brain Injury: A Randomized, Controlled, Double-Blinded Pilot Study, Shan H. Siddiqi, Nicholas T. Trapp, Carl D. Hacker, Timothy O. Laumann, Sridhar Kandala, Xin Hong, Ludwig Trillo, Pashtun Shahim, Eric C. Leuthardt, Alexandre R. Carter, David L. Brody Jan 2019

Repetitive Transcranial Magnetic Stimulation With Resting-State Network Targeting For Treatment-Resistant Depression In Traumatic Brain Injury: A Randomized, Controlled, Double-Blinded Pilot Study, Shan H. Siddiqi, Nicholas T. Trapp, Carl D. Hacker, Timothy O. Laumann, Sridhar Kandala, Xin Hong, Ludwig Trillo, Pashtun Shahim, Eric C. Leuthardt, Alexandre R. Carter, David L. Brody

Open Access Publications

No abstract provided.


Visual Impairment And Objectively Measured Physical Activity And Sedentary Behaviour In Us Adolescents And Adults: A Cross-Sectional Study, Lee Smith, Sarah E. Jackson, Shahina Pardhan, Guillermo Felipe López-Sánchez, Liang Hu, Chao Cao, Davy Vancampfort, Ai Koyanagi, Brendon Stubbs, Joseph Firth, Lin Yang Jan 2019

Visual Impairment And Objectively Measured Physical Activity And Sedentary Behaviour In Us Adolescents And Adults: A Cross-Sectional Study, Lee Smith, Sarah E. Jackson, Shahina Pardhan, Guillermo Felipe López-Sánchez, Liang Hu, Chao Cao, Davy Vancampfort, Ai Koyanagi, Brendon Stubbs, Joseph Firth, Lin Yang

Open Access Publications

No abstract provided.


Psychosocial Moderation Of Polygenic Risk For Cannabis Involvement: The Role Of Trauma Exposure And Frequency Of Religious Service Attendance, Jacquelyn L. Meyers, Emma C. Johnson, Vivia V. Mccutcheon, Kathleen K. Bucholz, Arpana Agrawal, Et Al. Jan 2019

Psychosocial Moderation Of Polygenic Risk For Cannabis Involvement: The Role Of Trauma Exposure And Frequency Of Religious Service Attendance, Jacquelyn L. Meyers, Emma C. Johnson, Vivia V. Mccutcheon, Kathleen K. Bucholz, Arpana Agrawal, Et Al.

Open Access Publications

No abstract provided.


History Of Fatigue In Multiple Sclerosis Is Associated With Grey Matter Atrophy, Miklos Palotai, Aria Nazeri, Michele Cavallari, Brian C. Healy, Bonnie Glanz, Stefan M. Gold, Howard L. Weiner, Tanuja Chitnis, Charles R.G. Guttmann Jan 2019

History Of Fatigue In Multiple Sclerosis Is Associated With Grey Matter Atrophy, Miklos Palotai, Aria Nazeri, Michele Cavallari, Brian C. Healy, Bonnie Glanz, Stefan M. Gold, Howard L. Weiner, Tanuja Chitnis, Charles R.G. Guttmann

Open Access Publications

No abstract provided.


Delineating And Validating Higher-Order Dimensions Of Psychopathology In The Adolescent Brain Cognitive Development (Abcd) Study, Giorgia Michelini, Deanna M. Barch, Yuan Tian, David Watson, Daniel N. Klein, Roman Kotov Jan 2019

Delineating And Validating Higher-Order Dimensions Of Psychopathology In The Adolescent Brain Cognitive Development (Abcd) Study, Giorgia Michelini, Deanna M. Barch, Yuan Tian, David Watson, Daniel N. Klein, Roman Kotov

Open Access Publications

No abstract provided.


Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya Jan 2019

Zbtb32 Restrains Antibody Responses To Murine Cytomegalovirus Infections, But Not Other Repetitive Challenges, Arijita Jash, You W. Zhou, Diana K. Gerardo, Tyler J. Ripperger, Bijal A. Parikh, Sytse Piersma, Deepa R. Jamwal, Pawel R. Kiela, Adrianus C. M. Boon, Wayne M. Yokoyama, Chyi S. Hsieh, Deepta Bhattacharya

Open Access Publications

No abstract provided.


Associations Of Autozygosity With A Broad Range Of Human Phenotypes, David W. Clark, Lihua Wang, Mary Feitosa, Dabeeru C. Rao, Et Al. Jan 2019

Associations Of Autozygosity With A Broad Range Of Human Phenotypes, David W. Clark, Lihua Wang, Mary Feitosa, Dabeeru C. Rao, Et Al.

Open Access Publications

No abstract provided.


Association Of Polygenic Liability For Alcohol Dependence And Eeg Connectivity In Adolescence And Young Adulthood, Jacquelyn L. Meyers, Emma C Johnson, Arpana Agrawal, Et Al Jan 2019

Association Of Polygenic Liability For Alcohol Dependence And Eeg Connectivity In Adolescence And Young Adulthood, Jacquelyn L. Meyers, Emma C Johnson, Arpana Agrawal, Et Al

Open Access Publications

Differences in the connectivity of large-scale functional brain networks among individuals with alcohol use disorders (AUD), as well as those at risk for AUD, point to dysfunctional neural communication and related cognitive impairments. In this study, we examined how polygenic risk scores (PRS), derived from a recent GWAS of DSM-IV Alcohol Dependence (AD) conducted by the Psychiatric Genomics Consortium, relate to longitudinal measures of interhemispheric and intrahemispheric EEG connectivity (alpha, theta, and beta frequencies) in adolescent and young adult offspring from the Collaborative Study on the Genetics of Alcoholism (COGA) assessed between ages 12 and 31. Our findings indicate that …


Contribution And Interaction Of Shiga Toxin Genes To Escherichia Coli O157:H7 Virulence, Gillian A M Tarr, Taryn Stokowski, Smriti Shringi, Phillip I Tarr, Stephen B Freedman, Hanna N Oltean, Peter M Rabinowitz, Linda Chui Jan 2019

Contribution And Interaction Of Shiga Toxin Genes To Escherichia Coli O157:H7 Virulence, Gillian A M Tarr, Taryn Stokowski, Smriti Shringi, Phillip I Tarr, Stephen B Freedman, Hanna N Oltean, Peter M Rabinowitz, Linda Chui

Open Access Publications

No abstract provided.


Association Between Itch And Cancer In 3836 Pediatric Pruritus Patients At A Tertiary Care Center, Micah Belzberg, Valerie A Larson, Raveena Khanna, Kyle A Williams, Yevgeniy Semenov, Sonja Ständer, Anna L Grossberg, Shawn G Kwatra Jan 2019

Association Between Itch And Cancer In 3836 Pediatric Pruritus Patients At A Tertiary Care Center, Micah Belzberg, Valerie A Larson, Raveena Khanna, Kyle A Williams, Yevgeniy Semenov, Sonja Ständer, Anna L Grossberg, Shawn G Kwatra

Open Access Publications

No abstract provided.


Transdermal Fluorescence Detection Of A Dual Fluorophore System For Noninvasive Point-Of-Care Gastrointestinal Permeability Measurement, Richard B Dorshow, J R Johnson, Martin P Debreczeny, I Rochelle Riley, Jeng-Jong Shieh, Thomas E Rogers, Carla Hall-Moore, Nurmohammad Shaikh, L Colleen Rouggly-Nickless, Phillip I Tarr Jan 2019

Transdermal Fluorescence Detection Of A Dual Fluorophore System For Noninvasive Point-Of-Care Gastrointestinal Permeability Measurement, Richard B Dorshow, J R Johnson, Martin P Debreczeny, I Rochelle Riley, Jeng-Jong Shieh, Thomas E Rogers, Carla Hall-Moore, Nurmohammad Shaikh, L Colleen Rouggly-Nickless, Phillip I Tarr

Open Access Publications

The intestinal mucosal barrier prevents macromolecules and pathogens from entering the circulatory stream. Tight junctions in this barrier are compromised in inflammatory bowel diseases, environmental enteropathy, and enteric dysfunction. Dual sugar absorption tests are a standard method for measuring gastrointestinal integrity, however, these are not clinically amenable. Herein, we report on a dual fluorophore system and fluorescence detection instrumentation for which gastrointestinal permeability is determined in a rat small bowel disease model from the longitudinal measured transdermal fluorescence of each fluorophore. This fluorophore technology enables a specimen-free, noninvasive, point-of-care gastrointestinal permeability measurement which should be translatable to human clinical studies.


Mri Quality Control For Low-Field Mr-Igrt Systems: Lessons Learned, H Michael Gach, Austen N Curcuru, Erin J Wittland, Borna Maraghechi, Bin Cai, Sasa Mutic, Olga L Green Jan 2019

Mri Quality Control For Low-Field Mr-Igrt Systems: Lessons Learned, H Michael Gach, Austen N Curcuru, Erin J Wittland, Borna Maraghechi, Bin Cai, Sasa Mutic, Olga L Green

Open Access Publications

PURPOSE: To present lessons learned from magnetic resonance imaging (MRI) quality control (QC) tests for low-field MRI-guided radiation therapy (MR-IGRT) systems.

METHODS: MRI QC programs were established for low-field MRI-

RESULTS: Image noise and artifacts were attributed to room noise sources, unsatisfactory system cabling, and broken RF receiver coils. Gantry angle-dependent magnetic field inhomogeneities were more prominent on the MRI-Linac due to the high volume of steel shielding in the gantry. B

CONCLUSIONS: There are significant technological challenges associated with implementing and maintaining MR-IGRT systems. Most of the performance issues were identified and resolved during commissioning.


Mechanism Of Microtubule Plus-End Tracking By The Plant-Specific Spr1 Protein And Its Development As A Versatile Plus-End Marker, Rachappa Balkunde, Layla Foroughi, Eric Ewan, Ryan Emenecker, Valeria Cavalli, Ram Dixit Jan 2019

Mechanism Of Microtubule Plus-End Tracking By The Plant-Specific Spr1 Protein And Its Development As A Versatile Plus-End Marker, Rachappa Balkunde, Layla Foroughi, Eric Ewan, Ryan Emenecker, Valeria Cavalli, Ram Dixit

Open Access Publications

No abstract provided.


Structural And Functional Evidence That Lipoprotein Lpqn Supports Cell Envelope Biogenesis In Mycobacterium Tuberculosis, Geoff C. Melly, Haley Stokas, Jennifer L. Dunaj, Fong Fu Hsu, Malligarjunan Rajavel, Chih-Chia Su, Edward W. Yu, Georgiana E. Purdy Jan 2019

Structural And Functional Evidence That Lipoprotein Lpqn Supports Cell Envelope Biogenesis In Mycobacterium Tuberculosis, Geoff C. Melly, Haley Stokas, Jennifer L. Dunaj, Fong Fu Hsu, Malligarjunan Rajavel, Chih-Chia Su, Edward W. Yu, Georgiana E. Purdy

Open Access Publications

No abstract provided.


Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen Jan 2019

Developmental Pathology Of Congenital Kidney And Urinary Tract Anomalies, Sanjay Jain, Feng Chen

Open Access Publications

No abstract provided.


Card And Rbpa Modify The Kinetics Of Initial Transcription And Slow Promoter Escape Of The Mycobacterium Tuberculosis Rna Polymerase, Drake Jensen, Ana R. Manzano, Christina L. Stallings, Eric A. Galburt Jan 2019

Card And Rbpa Modify The Kinetics Of Initial Transcription And Slow Promoter Escape Of The Mycobacterium Tuberculosis Rna Polymerase, Drake Jensen, Ana R. Manzano, Christina L. Stallings, Eric A. Galburt

Open Access Publications

No abstract provided.


Are The Intrinsically Disordered Linkers Involved In Ssb Binding To Accessory Proteins?, Min Kyung Shinn, Alexander G. Kozlov, Bihn Nguyen, Wlodek M. Bujalowski, Timothy M. Lohman Jan 2019

Are The Intrinsically Disordered Linkers Involved In Ssb Binding To Accessory Proteins?, Min Kyung Shinn, Alexander G. Kozlov, Bihn Nguyen, Wlodek M. Bujalowski, Timothy M. Lohman

Open Access Publications

No abstract provided.


Multiple Changes Underlie Allelic Divergence Of Cup2 Between Saccharomyces Species, Xueing C. Li, Justin C. Fay Jan 2019

Multiple Changes Underlie Allelic Divergence Of Cup2 Between Saccharomyces Species, Xueing C. Li, Justin C. Fay

Open Access Publications

No abstract provided.


Anchor Surgeon Views Of Patient Selection And Expectations For Periacetabular Osteotomy, Adam I. Edelstein, Karen Kaiser Tegal, Sara Shaunfield, Anchor Group, John C. Clohisy, Michael D. Stover Jan 2019

Anchor Surgeon Views Of Patient Selection And Expectations For Periacetabular Osteotomy, Adam I. Edelstein, Karen Kaiser Tegal, Sara Shaunfield, Anchor Group, John C. Clohisy, Michael D. Stover

Open Access Publications

No abstract provided.


Complications Associated With Combined Surgical Hip Dislocation And Periacetabular Osteotomy For Complex Hip Deformities, Adam I. Edelstein, Stephen T. Duncan, Sean Akers, Gail Pashos, Perry L. Schoenecker, John C. Clohisy Jan 2019

Complications Associated With Combined Surgical Hip Dislocation And Periacetabular Osteotomy For Complex Hip Deformities, Adam I. Edelstein, Stephen T. Duncan, Sean Akers, Gail Pashos, Perry L. Schoenecker, John C. Clohisy

Open Access Publications

No abstract provided.


Neutralizing Antibodies Against Mayaro Virus Require Fc Effector Functions For Protective Activity, James T. Earnest, Katherine Basore, Vicky Roy, Adam L. Bailey, David Wang, Galit Alter, Daved H. Fremont, Michael S. Diamond Jan 2019

Neutralizing Antibodies Against Mayaro Virus Require Fc Effector Functions For Protective Activity, James T. Earnest, Katherine Basore, Vicky Roy, Adam L. Bailey, David Wang, Galit Alter, Daved H. Fremont, Michael S. Diamond

Open Access Publications

No abstract provided.


Rory Regulates The Nlrp3 Inflammasome, Cyrielle Billon, Meghan H. Murray, Amer Avdagic, Thomas P. Burris Jan 2019

Rory Regulates The Nlrp3 Inflammasome, Cyrielle Billon, Meghan H. Murray, Amer Avdagic, Thomas P. Burris

Open Access Publications

No abstract provided.