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Graduate Theses, Dissertations, and Problem Reports (ETD)

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A Data-Driven Smart Proxy Model For A Comprehensive Reservoir Simulation, Faisal Alenezi Jan 2017

A Data-Driven Smart Proxy Model For A Comprehensive Reservoir Simulation, Faisal Alenezi

Graduate Theses, Dissertations, and Problem Reports (ETD)

The preferred common tool to estimate the performance of oil and gas fields under different production scenarios is numerical reservoir simulation. A comprehensive numerical reservoir model has tens of millions of grid blocks. The massive potential of existing numerical reservoir simulation models have gone unrealized because they are computationally expensive and time-consuming. Therefore, an effective alternative tool is required for fast and reliable decision making. To reduce the required computational time, proxy models have been developed. Traditional proxy models are either statistical or reduced-order models (ROM). They were developed to substitute complex numerical simulation with producing a representation of the …

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Novel Mechanisms Controlling The Expression Of The Antidiabetic Hepatokine Fibroblast Growth Factor 21, Kimberly M. Alonge Jan 2017

Novel Mechanisms Controlling The Expression Of The Antidiabetic Hepatokine Fibroblast Growth Factor 21, Kimberly M. Alonge

Graduate Theses, Dissertations, and Problem Reports (ETD)

The incidence of obesity has increased at an alarming rate during the past thirty years. Current therapies for the treatment and prevention of obesity and metabolic syndrome are ineffective and/or produce undesirable side effects. Fibroblast growth factor 21 (FGF21) is a liver derived hormone that mediates adaptive changes in hepatic glucose and lipid metabolism by elevating energy expenditure and reducing lipid storage. Pharmacological administration of FGF21 analogs in both animal and human models induces striking reversals of obesity and type 2 diabetes. However, the activity of FGF21 analogs exhibit short half-lives in blood circulation and are unsuitable for current treatment. …

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Monitoring And Control Framework For Advanced Power Plant Systems Using Artificial Intelligence Techniques, Ghassan Khalil Ismaeel Al-Sinbol Jan 2017

Monitoring And Control Framework For Advanced Power Plant Systems Using Artificial Intelligence Techniques, Ghassan Khalil Ismaeel Al-Sinbol

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation presents the design, development, and simulation testing of a monitoring and control framework for dynamic systems using artificial intelligence techniques. A comprehensive monitoring and control system capable of detecting, identifying, evaluating, and accommodating various subsystem failures and upset conditions is presented. The system is developed by synergistically merging concepts inspired from the biological immune system with evolutionary optimization algorithms and adaptive control techniques.;The proposed methodology provides the tools for addressing the complexity and multi-dimensionality of the modern power plants in a comprehensive and integrated manner that classical approaches cannot achieve. Current approaches typically address abnormal condition (AC) detection …

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Civil Religion And Ontological Threat, Matthew R. Arp Jan 2017

Civil Religion And Ontological Threat, Matthew R. Arp

Graduate Theses, Dissertations, and Problem Reports (ETD)

Dyadic conflict research within international relations is largely reliant on the analysis of differences in regime or leadership characteristics as a catalyst for conflict. This dissertation challenges traditional scholarship through the introduction of a unique approach that examines more fundamental differences between states. These fundamental historical and cultural differences, which are enshrined in a states' civil religion, offer insights into the behavior of states during crisis. The three primary questions of this dissertation are the following: What role does societal norms and cultural values have in threat perception? Why do states practice restraint in some crises and escalation of belligerence …

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In Vitro Study Of Retentive Properties Of Different Overdenture Attachment Systems On Straight And Divergent Dental Implants, Khalid Abdullaziz Azzouz Jan 2017

In Vitro Study Of Retentive Properties Of Different Overdenture Attachment Systems On Straight And Divergent Dental Implants, Khalid Abdullaziz Azzouz

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objectives: To evaluate the retention of Locator R-TX (ZEST Anchors LLC, Escondido, CA USA), Locator (ZEST Anchors LLC, Escondido, CA USA) and GPS (Implant Direct Sybron International, LLC, California, USA) dental implant attachment systems on parallel and divergent implants after sixteen months of simulated cyclic wear.;Methods: 30 acrylic blocks representing mandibular arches were used. Two Locator R-TX, two Locator, or two GPS abutment analogs were placed parallel or with 10 degrees of divergence in each block. The associated housings were picked up in corresponding acrylic blocks with clear Orthodontic resin (Dentsply GAC, Islandia, NY USA). The black processing liners in …

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Carbon Dioxide Capture Using Amine Functionalized Carbonaceous Materials From Bio-Refinery Waste Streams, Emmanuel Atta-Obeng Jan 2017

Carbon Dioxide Capture Using Amine Functionalized Carbonaceous Materials From Bio-Refinery Waste Streams, Emmanuel Atta-Obeng

Graduate Theses, Dissertations, and Problem Reports (ETD)

One of the greatest challenges in the world today is to replace exhaustible fossil fuel resources with renewable alternatives that will satisfy the increasing worldwide energy and chemical demands in a sustainable way. Using renewable precursors has a low impact on environmental health since it reduces pollution, greenhouse gas emissions and limits global warming and problems associated with waste management. Lignocellulosic biomass is the most available feedstock for developing sustainable chemicals and energy. A major challenge to the efficiency of the forest biorefinery industry is lack of suitable technologies for the conversion of its waste or by-products (lignin and hemicelluloses) …

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Bioacoustics And Behavior Of American Crocodiles In Belize, Miriam Boucher Jan 2017

Bioacoustics And Behavior Of American Crocodiles In Belize, Miriam Boucher

Graduate Theses, Dissertations, and Problem Reports (ETD)

American Crocodiles (Crocodylus acutus) are large-bodied crocodylians broadly distributed throughout coastal and lowland wetlands in the Americas. Despite their being large, charismatic megafauna, the study of American Crocodile ecology is still lacking in many areas. As such we assessed the behavior and bioacoustics of American Crocodiles in Belize to address the paucity of data regarding these two facets of American Crocodile ecology. We conducted behavioral observations from three sites in the coastal zone of Belize. We categorized American Crocodile behavior and recorded activity duration for observed behaviors. In conjunction with behavioral data, we also assessed study sites to quantify the …

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Elucidating Function In Early Diverging Non-Flagellated Fungi Using Metabolomics And Proteomics, Gregory R. Boyce Jan 2017

Elucidating Function In Early Diverging Non-Flagellated Fungi Using Metabolomics And Proteomics, Gregory R. Boyce

Graduate Theses, Dissertations, and Problem Reports (ETD)

The obligate lifestyle of many of the early diverging non-flagellated fungi have long precluded them from functional studies reserved primarily for their easily cultured, more derived counterparts. Modern --omics--based tools including transciptomics, proteomics and metabolomics have facilitated a better understanding of many fungi but have yet to be employed in the study of early diverging non-flagellated fungi with few exceptions. Using global and targeted metabolomics and prototeomics across the symbiotic spectrum, a series of studies were undertaken to better understand metabolism of three symbiotic interactions: two AM fungus-plant associations including Rhizophagus dimorphicus -- grass, R. clarus -- legume, and one …

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The Relationship Between Father Involvement And Paternal Emotion Socialization, Kayla E. Forshee Jan 2017

The Relationship Between Father Involvement And Paternal Emotion Socialization, Kayla E. Forshee

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this study was to examine the relationship between father involvement and emotion socialization. Fathers amount of time and quality of paternal involvement (e.g., engagement in childcare activities, secondary activities, and time spent in children's company) with their preschool aged children was assessed to determine if it influenced how fathers respond to the children's emotion (e.g., disappointment, anger, and anxiety). Heterosexual fathers (M = 39.46 yrs.) of children ages 3-5 years old were recruited from preschools and daycares in the larger metropolitan, D.C. area. Paternal self-report measures were used to measure father's involvement and their socialization strategies. Results …

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The Investigation Of Motor Primitives During Human Reaching Movements And The Quantification Of Post-Stroke Motor Impairment, Erienne Virginia Olesh Jan 2017

The Investigation Of Motor Primitives During Human Reaching Movements And The Quantification Of Post-Stroke Motor Impairment, Erienne Virginia Olesh

Graduate Theses, Dissertations, and Problem Reports (ETD)

Movement is a complex task, requiring precise and coordinated muscle contractions. The forces and torques produced during multi-segmental movement of the upper limbs in humans, must be controlled, in order for movement to be achieved successfully. Although a critical aspect of everyday life, there remain questions regarding the specific controller used by the central nervous system to govern movement. Furthermore, how this system is affected by neurological injuries such as stroke also remains in question. It was the goal of this thesis to examine the neurological control of movement in healthy individuals and apply these findings to the further investigation …

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Unifying The Visible And Passive Infrared Bands: Homogeneous And Heterogeneous Multi-Spectral Face Recognition, Nnamdi C. Osia Jan 2017

Unifying The Visible And Passive Infrared Bands: Homogeneous And Heterogeneous Multi-Spectral Face Recognition, Nnamdi C. Osia

Graduate Theses, Dissertations, and Problem Reports (ETD)

Face biometrics leverages tools and technology in order to automate the identification of individuals. In most cases, biometric face recognition (FR) can be used for forensic purposes, but there remains the issue related to the integration of technology into the legal system of the court. The biggest challenge with the acceptance of the face as a modality used in court is the reliability of such systems under varying pose, illumination and expression, which has been an active and widely explored area of research over the last few decades (e.g. same-spectrum or homogeneous matching). The heterogeneous FR problem, which deals with …

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Geotechnical Laboratory Testing For 2-D Fem Analysis Of Geomorphic And Planar Sloped Caps And Covers For Sustainable Mine Refuse Deposition, Sun Hee Park Jan 2017

Geotechnical Laboratory Testing For 2-D Fem Analysis Of Geomorphic And Planar Sloped Caps And Covers For Sustainable Mine Refuse Deposition, Sun Hee Park

Graduate Theses, Dissertations, and Problem Reports (ETD)

This thesis reports the findings of the application of Geomorphic Landform Design principles to the Royal Scot abandoned coarse coal refuse (CCR) pile located in Greenbrier County, West Virginia. The Royal Scot facility has many environmental concerns including severe erosion, acid-mine/rock drainage, and sediment transport. A cap and cover system is proposed to be implemented which incorporates the GLD principles. A two-layer cap and cover system will be used to reclaim the site and return it back to a stable state and reduce the production of acid-mine drainage. The system is composed of a hydraulic barrier composed of compacted CCR, …

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Historical Phenology Of West Virginia: 130 Years Of Spring Avian Migration And Wildflower Blooming, Lori M. Petrauski Jan 2017

Historical Phenology Of West Virginia: 130 Years Of Spring Avian Migration And Wildflower Blooming, Lori M. Petrauski

Graduate Theses, Dissertations, and Problem Reports (ETD)

Phenology, or the study of biological cycles in relation to the seasons, is a useful approach to study climate change and its effects on species. Analyzing historical records of phenology can give clues to understanding the future of ecosystems in relation to climate change. Specifically, using untapped sources of historical phenological data such as museum specimens, journals written by nature-minded citizens, and dated photographs can expand our temporal range of phenology data and provide a baseline with which to compare current phenology observations.;There is no central database for historical phenology data in West Virginia and there has been little research …

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Exploring Concentration And Duration Dependence In Hormesis, Maren S. Prediger Jan 2017

Exploring Concentration And Duration Dependence In Hormesis, Maren S. Prediger

Graduate Theses, Dissertations, and Problem Reports (ETD)

The phenomenon of hormesis, characterized by beneficial low-exposure stress-protective effects, has experienced increasing interest by the scientific community. Elucidating the underlying cellular signaling pathways that lead to a new homeostatic state can provide crucial information about new therapeutic targets to prevent and treat diseases. Commonly investigated for hormetic behavior are plant-based substances (phytochemicals), such as quercetin, epigallocatechin gallate, curcumin, and resveratrol. The polyphenol resveratrol, found in peanuts, grapes, and subsequently in wine, is known for a variety of effects---beneficial and detrimental---depending on the investigated cell type and concentration. In HepG2 cells, an increase in proliferation has been observed previously at …

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A Literature Review Of The Effects Of Home And Commercial Processing Methods On Nutritional And Sensory Properties Of Green Beans (Phaseolus Vulgaris), Emily Hope Bauman Jan 2017

A Literature Review Of The Effects Of Home And Commercial Processing Methods On Nutritional And Sensory Properties Of Green Beans (Phaseolus Vulgaris), Emily Hope Bauman

Graduate Theses, Dissertations, and Problem Reports (ETD)

A comprehensive review of current literature was conducted to investigate nutrient retention, texture and color during processing and storage of green beans. Consumers do not take into consideration of the effects of processing and storage on the nutritional and sensory quality of the green beans. Freezing and canning are the main processing methods used to extend the shelf-life of green beans. Both frozen and canned green beans are blanched during processing. Green beans are either frozen after blanching or for canning undergo additional thermal processing. Ascorbic acid was found to remain stable after steam blanching at 90°C for 3.5 minutes. …

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Scholars And Knowledge Sharing On Twitter, Pravija Krishna Jan 2017

Scholars And Knowledge Sharing On Twitter, Pravija Krishna

Graduate Theses, Dissertations, and Problem Reports (ETD)

There has always been an invisible gap between members of the scientific community - scholars (professors & researchers), science fans (subject matter experts) and novices (general public who are enthusiastic about science or any other field). This report aims at bridging that gap and exploring to what extent the scientic community is willing and able to share their knowledge with the general public. Several studies were conducted both on Twitter and manually. The results of these studies were vital in proposing a system that could help increase the level of sharing of knowledge by scholars and science fans in addition …

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Exposure Monitoring And Controlling Hazards In Additive Manufacturing Processes, Tyler John Kusich Jan 2017

Exposure Monitoring And Controlling Hazards In Additive Manufacturing Processes, Tyler John Kusich

Graduate Theses, Dissertations, and Problem Reports (ETD)

Additive manufacturing (AM) is a relatively new field that promises advancement in various disciplines such as medical, aerospace, and consumer products. One of the recent developments in additive manufacturing is with the use of metal powders, such as aluminum, nickel, and chromium. AM processes are projected to become more common as the technology advances and the applications spread into a variety of different industries. There are several health and safety risks that have been identified with the use of these powders, including combustible dust and health exposure issues. This study was aimed at looking at some of the issues with …

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Synthesis Of Znse@Zns Core-Shell Quantum Dots (Qds) For Bioimaging Applications, Yang He Jan 2017

Synthesis Of Znse@Zns Core-Shell Quantum Dots (Qds) For Bioimaging Applications, Yang He

Graduate Theses, Dissertations, and Problem Reports (ETD)

To date, malignancies have been categorized as one of the leading life-threatening diseases worldwide, mainly because of lack of imaging devices for detection of cancers at its early stage of development. In this case, the emergence of novel strategies which can be effectively used in early stage cancer detection and therapy continue to become an inevitable need and indispensable scope of and cancer field researchers, for which implementation of new technologies are required to advance the early detection and management of cancers. The biomedical imaging of the organs in the living system offers a viable approach to label and image …

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Dual Targeting Of The Mesenchymal And Amoeboid Pathways: A Viable Therapy Against Metastatic Breast Cancer, Brandon C. Jones Jan 2017

Dual Targeting Of The Mesenchymal And Amoeboid Pathways: A Viable Therapy Against Metastatic Breast Cancer, Brandon C. Jones

Graduate Theses, Dissertations, and Problem Reports (ETD)

Metastasis from the primary tumor site is the major cause of death in breast cancer, and acquisition of migration capacity is a key element for successful metastasis. Recently, it was found that expression of NEDD9, a focal adhesion associated scaffolding protein, could be used to switch between two types of single cell movement known as mesenchymal and amoeboid. Control of this "switch" can potentially open up new avenues of treatment against cancer metastasis. Simultaneous inhibition of both types of single cell movement may prevent cancer migration, thus decreasing cancer spreading and increasing survival of cancer patients. For example, forcibly pushing …

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3d Finite Element Seepage And Slope Stability Modeling Of A Geomorphic Landform Reclamation, Iuri Lira Santos Jan 2017

3d Finite Element Seepage And Slope Stability Modeling Of A Geomorphic Landform Reclamation, Iuri Lira Santos

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Royal Scot coal refuse pile in Greenbrier County, WV is being studied in order to reduce the Acid Mine Drainage (AMD) produced by this site. Two approaches to solve this problem were proposed: 1) a hydraulic barrier cover reclamation with a surface vegetative layer and 2) a land cover slope reclamation with a vegetative growth layer placement at the surface.;This thesis evaluated seepage and slope stability of the two proposed designs with a finite element modeling software in a transient analysis under unsaturated soil mechanics. Results from the model analysis were evaluated and further utilized to compare and contrast …

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Genetic Analysis Of The Biosynthesis Of Pharmaceutically Important Dihydroergot Alkaloids By Heterologous Expression Of Claviceps Gigantea Genes In The Fungus Neosartorya Fumigata, Paige E. Bragg Jan 2017

Genetic Analysis Of The Biosynthesis Of Pharmaceutically Important Dihydroergot Alkaloids By Heterologous Expression Of Claviceps Gigantea Genes In The Fungus Neosartorya Fumigata, Paige E. Bragg

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ergot alkaloids are a family of secondary metabolites produced by several species of fungi. The structural similarities of ergot alkaloids to neurotransmitters give them the ability to help treat several neurological and cognitive diseases, such as dementia, Alzheimer's and Parkinson's disease. These pharmaceuticals are currently being synthesized from more complex ergot alkaloids, however they would be more efficiently synthesized from dihydroergot alkaloids. Understanding the genes involved in the synthesis of dihydroergot alkaloids, such as dihydrolysergol and dihydrolysergic acid, and elucidating their pathways will be beneficial. The Mexican maize ergot pathogen Claviceps gigantea has been reported to produce dihydrolysergol, which is …

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Exploring Staff Turnover In A Large-Scale Ebt Implementation Initiative, Laurel A. Brabson Jan 2017

Exploring Staff Turnover In A Large-Scale Ebt Implementation Initiative, Laurel A. Brabson

Graduate Theses, Dissertations, and Problem Reports (ETD)

Staff turnover in the behavioral health field is a substantial and chronic problem with implications for both agencies and clients (Ben-Dror, 1994). Increased focus on the implementation of evidence-based treatments (EBT) has further highlighted the problems associated with turnover, as EBT trainings are particularly costly and time-consuming for clinicians and their agencies (Cook, Biyanova, & Coyne, 2009). The current study examined rates and predictors of turnover within an EBT implementation initiative designed to assess the effectiveness of three different training models. Data was collected from 110 families, 100 clinicians, 50 supervisors, and 50 administrators involved in the state-wide implementation of …

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Skeletal Muscle Arteriole Dysfunction And Microvessel Density In Metabolic Syndrome And Depression: How Exercise Can Be Used As An Intervention, Kayla Whitney Branyan Jan 2017

Skeletal Muscle Arteriole Dysfunction And Microvessel Density In Metabolic Syndrome And Depression: How Exercise Can Be Used As An Intervention, Kayla Whitney Branyan

Graduate Theses, Dissertations, and Problem Reports (ETD)

The present study examined the effect of unpredictable chronic mild stress (UCMS) on peripheral microvessel function in healthy and metabolic syndrome (MetS) rodents, and whether exercise training could prevent the vascular dysfunction associated with UCMS. Our initial hypothesis was that: 1) LZRs exposed to UCMS would have peripheral microvascular dysfunction similar to that evident in the OZRs controls due to a reduction in NO bioavailability and an increase in ROS production; 2) the comorbidity between MetS exposed to UCMS will exacerbate the already existing peripheral microvascular dysfunction; 3) exercise could limit the peripheral microvascular dysfunction by decreasing oxidative stress and …

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Using Long-Term Records To Investigate Watershed Nitrogen Supply And Demand Dynamics At The Fernow Experimental Forest, West Virginia, Usa, Mark Benjamin Burnham Jan 2017

Using Long-Term Records To Investigate Watershed Nitrogen Supply And Demand Dynamics At The Fernow Experimental Forest, West Virginia, Usa, Mark Benjamin Burnham

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fossil fuel combustion has caused elevated anthropogenic nitrogen (N) deposition onto forests in the northeastern United States since the middle of the 20th century, and has resulted in the supply of N exceeding the ecosystem N demand in many forests across the region. While the supply-demand imbalance is often attributed to elevated N inputs, a reduction in N demand may also make a significant contribution to diminished levels of N retention. Long-term records of N inputs, outputs, and stand dynamics at the Fernow Experimental Forest (FEF) in Tucker County, WV, provide a unique opportunity to study how changes in ecosystem …

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The Effect Of Implant Prostheses Complications On Patient Satisfaction, Jessica Elyse Canallatos Jan 2017

The Effect Of Implant Prostheses Complications On Patient Satisfaction, Jessica Elyse Canallatos

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objectives: To evaluate patient satisfaction with regards to implant prostheses and compare those who have experienced self-reported implant prostheses complications to those who have not. Through this observation, we intend to determine how and if implant-related complications affect the patients' self-reported quality of life.;Methods: In this retrospective study, data were gathered from 176 edentulous and partially dentate patients who have received implant prostheses including implant-supported crowns, implant supported overdentures, and hybrid prostheses from January 1, 2010 to December 31, 2014 at West Virginia University School of Dentistry (Morgantown, WV). Demographics and complications with implant prostheses were self-reported via a survey, …

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Reimagining The Ssmint Software Package, Kelly Cecil Jan 2017

Reimagining The Ssmint Software Package, Kelly Cecil

Graduate Theses, Dissertations, and Problem Reports (ETD)

We examine two proposed indexing algorithms taking advantage of the new SSMinT libraries. The two algorithms primarily differ in their selection of documents for learning. The batch indexing method selects some random number of documents for learning. The iterative indexing method uses a single randomly selected document to discover semantic signatures, which are then used to find additional related documents. The batch indexing method discovers one to three semantic signatures per document, resulting in poor clustering performance as evaluated by human cross-validation of clusters using the Adjusted Rand Index. The iterative indexing method discovers more semantic signatures per document, resulting …

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Recreation In The Brazilian Amazon - Understanding Visitor Profile And Perceptions Of Crowding, Lidiane Castro Gregory Jan 2017

Recreation In The Brazilian Amazon - Understanding Visitor Profile And Perceptions Of Crowding, Lidiane Castro Gregory

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of this thesis was to define the visitor profile of the Brazilian Amazon Basin using data from two different locations: The Tapajos National Forest and Anavilhanas National Park. This study also investigated possible issues regarding crowding. Overall data as well as segmented data were used in the analysis.;The methodology consisted of on-site interviews with survey days spread across weekdays and weekends. A total of 2534 usable surveys were collected from October 2015 to May 2015. All the analysis was conducted on SPSS. Frequencies, valid percentages, and means were used to describe the sample. For comparative analyzes between the …

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Removal Of Zinc Ions From Model Wastewater By Electrocoagulation, Xiujuan Chen Jan 2017

Removal Of Zinc Ions From Model Wastewater By Electrocoagulation, Xiujuan Chen

Graduate Theses, Dissertations, and Problem Reports (ETD)

This study has investigated the removal of zinc ions from the synthetic wastewater models by electrocoagulation (EC) with aluminum for both cathode and anode. The results showed that EC process had a great removal when it comes to zinc contaminated water. The effects of parameters on the EC performance have been systematically investigated, such as solution conductivity, electrode spacing, initial pH, current density and initial zinc concentration. Since the wastewater in real situations usually contains several types of metals, a series of mixed cases were also studied in this work.;The results indicated that current density is critical to EC performance, …

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Narratives Of Fracture: Class And Gender In Irish And Indian Postcolonial Domestic Fiction, Sreya Chatterjee Jan 2017

Narratives Of Fracture: Class And Gender In Irish And Indian Postcolonial Domestic Fiction, Sreya Chatterjee

Graduate Theses, Dissertations, and Problem Reports (ETD)

The world system, core-periphery, and combined and uneven development---all concepts originating in sociology and economic history have enjoyed a fresh resurgence in literary studies (Moretti 2001, Casanova 2007, Deckard et al 2015). This dissertation studies the novel as a "global form," and explores its conceptual engagement with, as well its inflection by, the changing core-periphery relationship in a globalizing world. I focus on five Irish and Indian women novelists, Elizabeth Bowen, Molly Keane, Jennifer Johnston, Mahasweta Devi and Kiran Desai. Arguably, India and Ireland occupy anomalous and analogous positions in the literary world-system. As a growing cultural-economic power, India is …

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Impact Of Incident Cancer On Coronary Artery Disease-Related Concomitant Medication Adherence, Short-Term Health And Economic Outcomes Among Elderly Medicare Beneficiaries With Coronary Artery Diseas, Ishveen Kaur Chopra Jan 2017

Impact Of Incident Cancer On Coronary Artery Disease-Related Concomitant Medication Adherence, Short-Term Health And Economic Outcomes Among Elderly Medicare Beneficiaries With Coronary Artery Diseas, Ishveen Kaur Chopra

Graduate Theses, Dissertations, and Problem Reports (ETD)

Coronary artery disease (CAD) is one of the most burdensome chronic conditions in the elderly. The two key goals of long-term management of CAD are (i) to reduce symptoms and ischemia and (ii) prevent myocardial infarction and death, by lowering lipids and blood pressure. Of all the risk reduction strategies, use and adherence to concomitant pharmacotherapy with statins and beta-blockers, angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin II receptor blockers (ARBs) have been shown to be highly effective and has become the cornerstone of CAD management. However, adherence to concomitant pharmacotherapy can be influenced by many factors including the development of …

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