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Analysis Of Pulsar Discoveries And Pulse Profile Variability: From Pulsar Candidates To Gravitational Wave Detector, William Carl Fiore

Graduate Theses, Dissertations, and Problem Reports (ETD)

Last year, pulsar timing arrays (PTAs) reported evidence of a gravitational-wave (GW) background at nanohertz frequencies, opening a new window into the Universe. PTAs measure GW-induced variations in the timing of radio pulses from millisecond pulsars (MSPs) in our Galaxy. In order for PTA experiments to confidently detect and characterize the GW background, they must continue to regularly observe many MSPs and measure their pulse times of arrival as precisely as possible. This motivates efforts to find new MSPs with pulsar surveys, and to study pulsars whose unusual behavior may give rise to excess noise in PTA data sets, potentially …

Α-Hydroxy C–H Functionalization Of Alcohols Via Boronic Acid, Hat, Photoredox Triad Catalytic System, Seth Christopher Cowan

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores the research that I have conducted in my time at West Virginia University. Most of my work has focused on the development of methods and studies to further understand the α-OH C–H functionalization of alcohols. This work involves a system of catalysts including photocatalysts, HAT catalysts, and boronic acid catalysts. Chapter 1 highlights a background for each of these areas. Photoredox catalysis has been an increasing area of chemistry over the past two decades as this technique can be used to design conditions to form new bonds in a selective manner through the utilization of light energy. …

Measures Of Feed Efficiency In Beef Cattle: Biological Basis And Effect On Response To Dietary Supplementation, Modoluwamu Idowu

Graduate Theses, Dissertations, and Problem Reports (ETD)

During the feedlot receiving period, newly weaned beef cattle face various stressors, including weaning, transportation, vaccination, and exposure to pathogens. Additionally, changes in diet and low dry matter intake contribute to nutrient deficiencies, heightening susceptibility to disease and performance declines. Therefore, we examined the effects of dietary supplementation with a multicomponent blend of prebiotics and probiotics on the health, immune status, metabolism, and performance of newly weaned beef steers during a 35-day receiving period. Our results showed that compared to the control group, the supplemental additive (SYNB) increased average daily gain (ADG), dry matter intake, and meal events during the …

Dough Rheology And Its Influence On Sheeting Behavior, Najat Albarakati

Graduate Theses, Dissertations, and Problem Reports (ETD)

Dough is the starting material for a large number of baked products, including cookies, crackers and bread. In commercial food processing operations, it is desired to obtain the same product and with the same dimensions in a reproducible manner in order to minimize waste. In the case of dough, the flour used, and the nature and amount of ingredients employed depend on the specific product and the market served. This research was aimed at relating cracker dough rheology to sheeting behavior between two counter-rotating rollers. The sheet that is formed is used to punch out the crackers that are then …

Machine Learning-Assisted Multiscale Simulation And Design Optimization Of Composite Jackets Under Low-Velocity Impacts, Masoud Mohammadi

Graduate Theses, Dissertations, and Problem Reports (ETD)

This research presents the development of a data-driven machine learning-assisted approach to simulate and optimize the design of composite materials subjected to low-velocity impacts. It focuses on a specific type of hybrid composite comprised of fiberglass and Kevlar fabrics stitched with Kevlar threads. The study begins by creating a multiscale finite element simulation for the composite under a low-velocity impact, which operates across three scales: microscale, mesoscale, and macroscale. This simulation accepts various inputs, such as different layer configurations and orientations, and provides impact outputs including maximum load and energy absorption capacity and displacement at failure.

Python and MATLAB scripts …

Nickel-Catalyzed Regioselective Three-Component Coupling Of Phenyl Vinyl Sulfones With Alkynes, Stephen M. Long

Graduate Theses, Dissertations, and Problem Reports (ETD)

Benzene rings are some of the most prevalent motifs found in small molecule drugs with only a few dominant substitution patterns, 1-, 1,2-, 1,4-, and 1,2,4-. Nucleophilic aromatic substitution and electrophilic aromatic substitution are traditional methods for the synthesis of substituted benzenes and are robust and commonly used by chemical manufacturers, which explains in part the observed distribution of substitution patterns. Current methods to access substituted benzenes comprise of transition-metal-catalyzed C-H activation, transition-metal-catalyzed cross-coupling, and aryne chemistry. In general, the present methods require directing/leaving groups in specific positions to proceed, which inherently puts a limitation on substrate scope. Transition-metal-catalyzed [2+2+2] …

An Inhibitory Recurrent Network In The Olfactory System, Farzaan Salman

Graduate Theses, Dissertations, and Problem Reports (ETD)

Neuromodulatory circuits are a necessary component of neural flexibility as they are able to act differentially depending on the receptors expressed by their downstream targets. Identifying the synaptic partners of modulatory neurons and determining the neurotransmitter and receptor content of these partners is necessary to identify the rules governing neuromodulatory circuits. In this study, I characterized the circuit of the contralaterally projecting, serotonin-immunoreactive deutocerebral neurons (CSDns), the sole synaptic source of the neuromodulator serotonin in the olfactory circuit of Drosophila melanogaster, by identifying the strongest synaptic partners of the CSDns, and the expression of genes encoding neurotransmitters and receptors of …

Experimental Verification And Time-Resolved Bispectral Analysis Of Nonlinear Coupling In The Toroidicity-Induced Alfv´En Eigenmode Spectrum, Gregory Allen Riggs

Graduate Theses, Dissertations, and Problem Reports (ETD)

In magnetically-confined fusion devices, the toroidicity-induced Alfv´en eigenmode (TAE) is a well-studied, weakly stable solution of the linearized ideal magnetohydrodynamic (MHD) equations. Due to intrinsic coupling of poloidal harmonics of the shear Alfv´en wave (SAW) in toroidal geometry, the rotational transform of magnetic field lines modulates the effective index of refraction, ensuring gaps in the so-called “Alfv´en continuum.” Experimental verification of theoretical predictions for various parameters of interest (i.e., frequency, mode structure, instability threshold, etc.) is established in the literature.

We present the first systematic study of TAE-TAE phase coherence in an experimental device, using the DIII-D tokamak. Crucially, nonlinear …

The Relationship Between Metacognition, Study Strategies, And Students’ Performances In General Chemistry And Organic Chemistry Courses, Nghiem Uy Tieu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Many students find General Chemistry challenging, and studies have shown a link between students’ grades in chemistry and a decrease in interest in STEM fields. Similarly, Organic Chemistry has also been typically identified as a difficult course for many undergraduate students and has a notoriously high failure rate. Numerous studies have explored various methods to enhance students’ performance and experience in both General Chemistry and Organic Chemistry, but there hasn’t been much focus on students’ study strategies. In addition, metacognition, the skill of thinking about one’s thinking, had been proven in studies as a vital role in enhancing students’ achievements. …

The Search, The Localization, And The Characterization: Fast Radio Transients, Reshma Anna Thomas

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fast radio transients are energetic bursts in centimeter or meter wave-lengths, lasting only milliseconds, and originating from both Galactic and extra-Galactic sources. In our Galaxy, these transients primarily originate from pulsars, which are rotating neutron stars. The more energetic extra-galactic transients, known as fast radio bursts (FRBs), have unknown origins. This thesis explores various techniques, including single dish and interferometric observations, to detect and accurately localize fast radio transients. It also investigates how the propagation effects of radio waves can reveal characteristics of the local environment and potential FRB sources. Furthermore, it demonstrates how FRBs can be used to study …

1d Geo-Mechanical Model Analysis Of The Mip 1s And Drilling Process Optimization In The Deep Appalachian Basin, Georges Brown Liwuitekong Dongho

Graduate Theses, Dissertations, and Problem Reports (ETD)

The proposed paper assesses the geological and geomechanical characteristics of the geothermal deep direct-use MIP 1S well in the Appalachian basin. The assessment utilizes a comprehensive suite of well logs, sidewall core analysis, and well injection tests to determine continuous elastic and rock strength properties. Stress and pore pressure profiling are conducted, and a validated 1D-geomechanical model is developed. This model undergoes analysis through wellbore stability assessments and comparisons with drilling events. The 1D-geomechanical model demonstrates a high degree of agreement with wellbore observations, revealing suboptimal execution of drilling practices, particularly utilizing mist air drilling up to 8868 feet. This …

Machine Learning Maintenance Costs Prediction Model For Heavy-Duty Alternative Fuel And Diesel Vehicles, Esteban Fernandez Villar

Graduate Theses, Dissertations, and Problem Reports (ETD)

Medium- and Heavy-Duty Vehicles (MHDVs) are essential to global logistics and transportation. Around 77% of these vehicles are diesel-powered due to its powertrain mechanical characteristics that make them reliable and energy efficient. However, the environmental implications of diesel combustion, particularly its direct contribution to air pollution and greenhouse gas (GHG) emissions, have increased the interest in alternative fuel vehicles (AFVs). These alternatives include Natural Gas (NG), Propane, Hybrid Electric Vehicles (HEVs), and Battery Electric Vehicles (BEVs), each presenting unique benefits and challenges in terms of required fueling infrastructure, energy efficiency, environmental impact, and total cost of operation (TCO). Maintenance costs …

A Multi-Wavelength Determination Of The Total Luminosity And Star Formation Rate Of The Milky Way, Joshua L. Mascoop

Graduate Theses, Dissertations, and Problem Reports (ETD)

The star formation rate (SFR) of the Milky Way is poorly understood in comparison to the SFR of other galaxies. In order to better find the Galaxy's place in the universe, it is imperative to understand the star formation activity occurring within it. We characterize the Galactic \hii\ region luminosity function (LF) at multiple infrared and radio wavelengths using a sample of 797 first Galactic quadrant \hii regions compiled from the WISE Catalog of Galactic \hii Regions. This sample is statistically complete for all regions powered by single stars of type O9.5V and earlier.

We find that neither a single …

Advances In Machine Learning Aided Seismic Interpretation And Inversion For Subsurface Characterization, Tobi Micheal Ore

Graduate Theses, Dissertations, and Problem Reports (ETD)

Geophysical data are used to “remotely sense” the subsurface to illuminate structures, stratigraphy, and features that are of interest in the exploration for energy, suitable storage for carbon dioxide, geothermal development, and environmental considerations. The interpretations of these data typically are regarded as partially an art, as it depends on the experience of the interpreter. This is further exacerbated with the big data era as this data is large and takes several days, even longer, to manually interpret. To bridge this gap of speed and subjective bias, machine learning has been successfully applied to automate the geophysical interpretation process. This …

C–H Alkylation Of Diol Substrates Using Bifunctional Boronic Acid Catalysts, Matthew Ryan Ross

Graduate Theses, Dissertations, and Problem Reports (ETD)

Boronic acid catalysts in combination with a Lewis base have been used in previous work to perform site-selective C–H alkylation reactions targeting the α-hydroxy C–H bond of diols through a photoredox activated hydrogen atom transfer. This is done by accessing a tetracoordinate boronic acid – Lewis base complex which then mediates the hydrogen atom transfer. The research hypothesizes that combining the boronic acid and Lewis base into one molecule not only simplifies the reaction but also has the potential to unlock C–H alkylation sites previously inaccessible. This is plausible because the Lewis base portion of the synthesized bifunctional boronic acid …

Estimating Home Range Size And Density Of White-Tailed Deer (Odocoileus Virginianus) In West Virginia, Sarah M. Pesi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Big game hunting is an important source of revenue and recreation in the United States. Of big game species, white-tailed deer (Odocileus virginianus) are the most heavily pursued. White-tailed deer are a widespread generalist species, capable of existing at high densities. Hunting is often used as the primary method of managing deer populations, particularly in the eastern United States, where there is a lack of large predators. When populations reach high densities, there can be negative effects on the environment and conflicts with humans. Managers must consider both creating adequate hunting opportunities and reducing negative impacts when managing …

Synthetic Elaboration Of Β-Carbonyl Alkylboronic Esters, Mason D. Hamilton Ph.D.

Graduate Theses, Dissertations, and Problem Reports (ETD)

Organoboron compounds are some of the most synthetically versatile compounds in organic chemistry due to the many valuable transformations of the C-B bond. This synthetic versatility combined with the pharmacophoric nature of carboxylic acids has led to an increased interest in the one-pot difunctionalization of vinyl arenes using CO₂ and pinacol boranes. Recently, much progress has been made to improve the scope and versatility of boracarboxylation reactions to now include electron-deficient and α-methyl substituted vinyl arenes. However, the potential transformations of boracarboxylated products have remained unexplored. Here, methodologies to transform the β-aryl alkylboronic ester into new C-C, C-N, and …

Enhancing Pipeline Simulations Through Artificial Intelligence And Machine Learning: A Smart Proxy Modelling Approach, Afeez Shittu

Graduate Theses, Dissertations, and Problem Reports (ETD)

ABSTRACT

Enhancing pipeline simulations is essential for improving operational efficiencies and effectively managing risks in the oil and gas industry. Traditional pipeline simulators, relying heavily on mathematical modeling assumptions, often face limitations due to their high energy and computational demands. This thesis addresses these challenges by introducing an innovative approach that integrates artificial intelligence (AI) and machine learning (ML) through a smart proxy model, offering a more efficient, cost-effective, and flexible alternative to conventional full-physics models used in pipeline simulation software.

The primary aim of this research is to develop and implement a smart proxy model capable of accurately predicting …

Fluid-Rock And Fluid-Steel Interaction In Geothermal Energy Development In The Appalachain Basin, Samuel H. Bowman

Graduate Theses, Dissertations, and Problem Reports (ETD)

The ever-increasing demand for clean energy requires creative solutions. In the United States, unconventional energy sources such as geothermal are conventionally limited to the western half of the country. The Appalachian Basin in the Eastern United States is one such possible creative solution, although the comparatively low temperature gradient presents a significant challenge to delivering economically feasible geothermal energy. An emerging technology is enhanced geothermal systems, these are engineered reservoirs where a working fluid (typically water) is cycled between the subsurface energy source and the energy collection facility at the surface. The liquid water interacts with the geothermal reservoir rock …

Implementation Of Bayesian Statistics To Answer Diverse Engineering Questions: Applications In Cancer Immunology And Engineering Education, Anika C. Pirkey

Graduate Theses, Dissertations, and Problem Reports (ETD)

Quantitative Systems Pharmacology (QSP) refers to a mechanistic modeling approach used for assessing potential therapeutics by linking the molecular and cellular level mechanisms of the disease and therapeutic to the system-wide dynamics and clinical endpoints relevant to the disease. Although the field of QSP is still in its relative infancy, the mathematical methodology employed to predict the kinetics of these systems are not new and can be applied to a wide variety of systems. For instance, similar to QSP’s goal of guiding the development of novel therapeutics for various disease states, there exists a need to develop novel interventions in …

A Quality Improvement Initiative To Reduce Preanalytical Blood Gas Errors, Layla Haver Newbrough

Graduate Theses, Dissertations, and Problem Reports (ETD)

Abstract

Introduction: Laboratory testing is one of the most commonly performed procedures in healthcare and resulting data are paramount to clinical decision making. Background: Preanalytical blood gas laboratory errors often stem from the incorrect recording of a patient’s fraction of inspired oxygen (FiO2) within the laboratory collection application. Incorrect FiO2 may cause erroneous results or delays in reporting results that have the potential to negatively impact patient safety and medical management.

Purpose: The purpose of this quality improvement initiative was to reduce the occurrence of preanalytical blood gas laboratory errors. Methods/Interventions: This initiative combined modification of the laboratory collection application …

Defining Success For An Introductory Mathematics Non-Stem Pathway Course, Clark D. Metz

Graduate Theses, Dissertations, and Problem Reports (ETD)

The enduring debate surrounding college algebra, traditionally a gateway for STEM pathways, underscores the necessity for curricular evolution in response to the rising popularity of non-STEM majors. This dissertation explores the success of an applied college algebra course designed for non-STEM students. The study aimed to determine whether this alternative course could meet diverse student needs while promoting academic achievement and fostering positive attitudes towards mathematics. Findings revealed through a novel approach of a difference-in-differences analysis that students enrolled in the applied college algebra course exhibited higher pass rates due to the introduction of the new course. The lower failure …

Hepatic Mrna Expression Of Innate And Adaptive Immune Genes In Beef Steers With Divergent Residual Body Weight Gain, Deborah Ologunagba

Graduate Theses, Dissertations, and Problem Reports (ETD)

Immune system function is critical to maintaining the health and increasing productivity of cattle, affecting both their growth and their disease resistance. In an efficient immune system, the liver assumes an integral function in detoxification and metabolic processes and contributes substantially to overall production and immunity. In this study, we evaluated the hepatic mRNA expression of genes involved in innate and adaptive immunity in crossbred beef steers with either a positive or negative residual body weight gain (RADG). Positive-RADG beef steers (n = 8; RADG = 0.76 kg/d) and negative-RADG beef steers (n = 8; RADG = -0.64 kg/d) were …

Ung: A Diagnostic Standard C Library, Jakob Knute Kaivo

Graduate Theses, Dissertations, and Problem Reports (ETD)

Undefined behavior in C programs is a major source of unreliable software. Many of the most common exploitable software vulnerabilities can be traced directly to undefined behavior. In the increasingly connected world, a successful attack can cost the victim millions of dollars to recover from. While static program analysis aids in identifying undefined behavior, testing indicates that even the best static analysis tools correctly identifies about 35% of these defects. This dissertation introduces UNG’s Not GNU (UNG), a standard C library designed to mitigate undefined behavior. Where others have seen opportunities for optimization, UNG makes every effort to identify undefined …

Additive-Dependent Regioselective Boracarboxylation Of Alkenes Using Low Valent Copper And Co2, Carly H. Gordon Ph.D.

Graduate Theses, Dissertations, and Problem Reports (ETD)

As a major greenhouse gas, carbon dioxide (CO₂) is an abundant and renewable C₁ feedstock, and developing methods for fixing CO₂ into high-value products is a major interest for the movement of greener chemistry. The boracarboxylation of alkenes provides access to difunctionalized products containing pharmaceutically relevant motifs, including carboxylic acids and boron-containing moieties. Significant work has been done to improve the versatility and efficiency of this methodology, with the recent expansion into a wide variety of terminal alkenes. The use of different phosphine and alkene additives have demonstrated positive effects on reaction rates and productivity, indicating …

Taking The Red Pill: A Content Analysis Of Ambivalent Sexism And Precarious Manhood In Alpha Male Podcasts, Madalen Lea Fields

Graduate Theses, Dissertations, and Problem Reports (ETD)

Podcasts have become increasingly popular across various platforms (e.g., Spotify or Apple podcasts). A more recent trend is the emergence of “alpha male” podcasts. The goal of these podcasts is to instruct young men how to stop being “betas” and on achieving “alpha male” status. These podcasts are a subset of the manosphere, a term used to describe media focused especially on hegemonic masculinity, which is characterized by their promotion of misogynistic beliefs and sexist rhetoric. Drawing upon social science research, three forms of sexism (i.e., ambivalent sexism, precarious manhood and violence against women) serve as analytical frameworks for understanding …

Life Cycle Impacts Of Hardwood Forest Resources For Sustainable Bioenergy And Bioproducts In The Eastern United States, Jinghan Zhao

Graduate Theses, Dissertations, and Problem Reports (ETD)

A life-cycle impact assessment of hardwood resources across the eastern United States was conducted based on the life-cycle inventory data for hardwood forest resource management and was integrated with the Forest Vegetation Simulator (FVS). This integration allowed for the analysis of forest carbon dynamics in the four subregions: northeast (NE), mid-Atlantic (MA), southeast (SE), and northcentral (NC). The system boundary was selected to be consistent with the A1 module (extraction and upstream production) required by an Environmental Product Declaration (EPD) for wood products. The results indicated that uneven-aged management (UA) yielded higher carbon stocks than even-aged management (EA) across all …

Low Power Remote Sensing System For Ceramic Thermocouples, Syed Khaleduzzaman

Graduate Theses, Dissertations, and Problem Reports (ETD)

The ceramic thermocouple sensor is a promising alternative to traditional thermocouple due to their corrosion resistance and cost-effective manufacturing. Currently, no electronic Interface or Integrated Circuit solution is commercially available which can be used to interface these thermocouples at low-cost and low power for accurate temperature measurement. An electronic system is needed to use these ceramic sensors which consumes less amount of power for an extensive period of time with remote monitoring option.

This thesis proposes a low-power electronic remote sensing system that works for ceramic thermocouples. The system consists of three parts. They are battery-operated sensor node electronic circuit, …

Experimental And Chemical Modeling Of Applied Dc Electric Field Induced H2 – Air Axisymmetric Laminar Co-Flow Diffusion Flames With Low Carbon Impurities, Susith Dilshan Pathmasiri Gunamuni Halowitage

Graduate Theses, Dissertations, and Problem Reports (ETD)

The effect of externally applied DC electric fields on flame structure was investigated in a stationary atmospheric axisymmetric laminar H₂–Air flame with less than 100 ppm carbon equivalent impurities. Flame OH chemiluminescence signals were recorded using a UV-sensitive CCD array as a function of voltage (+10 to -10 kV) applied to a stainless-steel ring electrode placed around the burner nozzle. Changes in chemiluminescence signal are reported as a function of electrode height above the burner, airflow, and fuel composition. Significant changes in OH* distributions were observed for voltages below -5 kV. Under optimum conditions, the height of the …

Studies In Nonlinear Chemical Dynamics Of Propagating Precipitation Waves, Md Boshir Ahmed

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation explores the intricate dynamics of pattern formation in nonlinear chemical systems, specifically focusing on the phenomena of propagating waves and Liesegang patterns in aluminum and zinc hydroxide systems. Through a combination of experimental setups and theoretical models, the study delves into the mechanisms driving these patterns, providing insights into their formation, evolution, and underlying principles.

The research begins with an introduction to nonlinear dynamics and pattern formation, emphasizing the significance of these concepts in understanding complex natural systems. It then moves into a detailed examination of Liesegang bands, discussing classical and reverse systems, and introducing the redissolution process …