Digital Commons Network^™

Rapid Increases In Obesity In Jamaica, Compared To Nigeria And The United States, Ramón A. Durazo-Arvizu, Amy Luke, Richard S. Cooper, Guichan Cao, Lara Dugas, Adebowale Adeyemo, Michael Boyne, Terrence Forrester

Faculty Publications

Background. Weight gain in adulthood is now common in many populations, ranging from modest gains in developing countries to a substantial percentage of body weight in some Western societies. To examine the rate of change across the spectrum of low to high-income countries we compared rates of weight change in samples drawn from three countries, Nigeria, Jamaica and the United States. Methods. Population samples from Nigeria (n = 1,242), Jamaica (n = 1,409), and the US (n = 809) were selected during the period 1995-1999 in adults over the age of 19; participation rates in the original survey were 96%, …

Maximal Exercise Electrocardiography Responses And Coronary Heart Disease Mortality Among Men With Diabetes Mellitus, G. William Lyerly, Xuemei Sui, Timothy S. Church, Carl J. Lavie, Gregory A. Hand, Steven N. Blair

Faculty Publications

Background - An abnormal ECG during maximal exercise testing has been shown to be a powerful predictor of future coronary heart disease (CHD) mortality in asymptomatic men. However, little is known about the relationship between exercise ECG responses and CHD risk in men with diabetes mellitus.

Methods and Results - We examined the association between exercise ECG responses and mortality in 2854 men with documented diabetes mellitus (mean age 49.5 years) who completed a maximal treadmill exercise test during the period from 1974 to 2001 and who were without a previous cardiovascular disease (CVD) event at baseline. Mortality due to …

Themes And Trends Of Journal Of Family And Economic Issues: A Review Of Twenty Years (1988–2007), Jeffrey P. Dew

Faculty Publications

This review article examines the progress and impact of the Journal of Family and Economic Issues (JFEI) between 1988–2007. Over the past 20 years, JFEI has become a major journal publishing articles on the relationship between families and economic systems. JFEIcontributed to both the economic and family studies disciplines by publishing articles that explore the interface of these two disciplines. Between 1988 and 2007, JFEI published articles on a variety of themes not often found in other economic or family studies journals such as family resource management, consumer attitudes and behaviors, and economic issues and family relationships. Other unique …

The Changing Role Of Physicians In Disaster Management And Hospital Incident Command, F. Matthew Mihelic, M. David Stockton, Stephen A. Cole, Gregory H. Blake

Faculty Publications

Recent changes in governmental policy toward disaster medicine and hospital incident command foreshadow a significant change in the role that physicians will play in disaster preparedness and response. The distinct discipline of Disaster Medicine has received authoritative recognition and promotion in the recent Homeland Security Presidential Directive 21, and recently established guidelines for incident command within hospitals have included a new position designated as “Medical/Technical Specialist(s)” that will assist the Incident Commander in disaster-related decision-making. This is a multidisciplinary position, and its functions can be filled by one or more individuals. As physician training and competency in Disaster Medicine increases, …

Genome Analysis Of The Platypus Reveals Unique Signatures Of Evolution, Wesley C. Warren, La Deana W. Hillier, Jennifer A. Marshall Graves, Ewan Birney, Chris P. Ponting, Frank Grützner, Katherine Belov, Webb Miller, Laura Clarke, Asif T. Chinwalla, Shiaw Pyng Yang, Andreas Heger, Devin P. Locke, Pat Miethke, Paul D. Waters, Frédéric Veyrunes, Lucinda Fulton, Bob Fulton, Tina Graves, John Wallis, Xose S. Puente, Carlos López-Otín, Gonzalo R. Ordóñez, Evan E. Eichler, Lin Chen, Ze Cheng, Janine E. Deakin, Amber Alsop, Katherine Thompson, Patrick Kirby, Anthony T. Papenfuss, Matthew J. Wakefield, Tsviya Olender, Doron Lancet

Faculty Publications

We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a coat of fur adapted to an aquatic lifestyle; platypus females lactate, yet lay eggs; and males are equipped with venom similar to that of reptiles. Analysis of the first monotreme genome aligned these features with genetic innovations. We find that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypus …

En-Gendering The Couple-Deity Relationship: Clinical Implications Of Power And Process, Brandt C. Gardner, Mark H. Butler, Ryan B. Seedall

Faculty Publications

Spiritual practices are increasingly accommodated by therapists working with religious couples. While research documents potential benefits, spiritual practices such as prayer may invoke an interpretive couple-God relationship distorted by pathogenic processes in one or both spouses. A survey administered to 78 religious couples examined the influence of power/gender as it relates to couples’ harmful triangulation with Deity. Results suggest that harmful triangulation with Deity does occur to some degree in couple relationships, that there are significant differences by gender, and that spouses’ tendencies to triangulate are correlated with one another. We discuss these results from a systemic-feminist perspective, and offer …

Can Megavoltage Computed Tomography Reduce Proton Range Uncertainties In Treatment Plans For Patients With Large Metal Implants?, Wayne D. Newhauser, Annelise Giebeler, Katja M. Langen, Dragan Mirkovic, Radhe Mohan

Faculty Publications

Treatment planning calculations for proton therapy require an accurate knowledge of radiological path length, or range, to the distal edge of the target volume. In most cases, the range may be calculated with sufficient accuracy using kilovoltage (kV) computed tomography (CT) images. However, metal implants such as hip prostheses can cause severe streak artifacts that lead to large uncertainties in proton range. The purposes of this study were to quantify streak-related range errors and to determine if they could be avoided by using artifact-free megavoltage (MV) CT images in treatment planning. Proton treatment plans were prepared for a rigid, heterogeneous …

The Practical Effects Of Delegation: Agencies And The Zoning Of Public Land And Seas, Josh Eagle

Faculty Publications

No abstract provided.

Physical Activity And Neighborhood Resources In High School Girls, Russell R. Pate, Natalie Colabianchi, Dwayne E. Porter, Maria João C. A. Almeida, Felipe Lobelo, Marsha Dowda

Faculty Publications

Background - Physical activity behavior is influenced by a person's physical environment, but few studies have used objective measures to study the influences of the physical environment on physical activity behavior in youth. The purpose of this study was to examine the relationship between selected neighborhood physical activity resources and physical activity levels in high school girls.

Methods - Participants were students in schools that had participated in a large physical activity intervention trial. The 3-Day Physical Activity Recall was completed by 1506 12th-grade girls. Data on physical activity facilities and resources in the participating communities were collected using a …

Temperature-Dependent Development, Survival, And Potential Distribution Of Ischnodemus Variegatus (Hemiptera: Blissidae), A Herbivore Of West Indian Marsh Grass, Rodrigo Diaz, William A. Overholt, J. P. Cuda, Paul D. Pratt, Alison Fox

Faculty Publications

The bug Ischnodemus variegatus (Signoret) (Hemiptera: Blissidae) is an adventive herbivore, native to South America that feeds in the invasive grass Hymenachne amplexicaulis (Rudge) Nees (Poaceae). This grass is a problematic weed in Florida and Australia, but it is a highly valued forage in Mexico, Cuba, and Venezuela. We studied the influence of nine constant temperatures (8-38°C) on the developmental time and survival of I. variegatus. Complete egg and nymphal mortality occurred at temperatures ≤20.5°C and at 38°C. Developmental time decreased linearly with temperature until 28-30°C and then increased at 33°C. Mortality of first, second, and third instars was high …

Chiral Recognition Of Amino Acids By Use Of A Fluorescent Resorcinarene, Gerald I. Richard, Hadi M. Marwani, Shan Jiang, Sayo O. Fakayode, Mark Lowry, Robert M. Strongin, Isiah M. Warner

Faculty Publications

The spectroscopic properties of a chiral boronic acid based resorcinarene macrocycle employed for chiral analysis were investigated. Specifically, the emission and excitation characteristics of tetraarylboronate resorcinarene macrocycle (TBRM) and its quantum yield were evaluated. The chiral selector TBRM was investigated as a chiral reagent for the enantiomeric discrimination of amino acids using steady-state fluorescence spectroscopy. Chiral recognition of amino acids in the presence of the macrocycle was based on diastereomeric complexes. Results demonstrated that TBRM had better chiral discrimination ability for lysine as compared to the other amino acids. Partial least squares regression modeling (PLS-1) of spectral data for macrocycle-lysine …

Post-Allergen Challenge Inhibition Of Poly(Adp-Ribose) Polymerase Harbors Therapeutic Potential For Treatment Of Allergic Airway Inflammation, A. S. Naura, C. P. Hans, M. Zerfaoui, D. You, S. A. Cormier, M. Oumouna, A. H. Boulares

Faculty Publications

Background: Identifying therapeutic drugs that block the release or effects of T-helper type 2 (Th2) cytokines after allergen exposure is an important goal for the treatment of allergic inflammatory diseases including asthma. We recently showed, using a murine model of allergic airway inflammation, that poly(ADP-ribose) polymerase (PARP) plays an important role in the pathogenesis of asthma-related lung inflammation. PARP inhibition, by single injection of a novel inhibitor, thieno[2,3-c]isoquinolin-5-one (TIQ-A), before ovalbumin (OVA) challenge, prevented airway eosinophilia in C57BL/6 mice with concomitant suppression of Th2 cytokine production and mucus secretion. Objective: To evaluate the efficacy of the drug when it is …

Culture-Independent Identification Of Gut Bacteria In Fourth-Instar Red Imported Fire Ant, Solenopsis Invicta Buren, Larvae, Albert H. Lee, Claudia Husseneder, Linda Hooper-Bùi

Faculty Publications

Red imported fire ants (RIFA), Solenopsis invicta Buren, are medical, urban, and agricultural pests from South America. They are successful invaders due to their preference for disturbed habitats, high reproductive rates, and the ability to feed on a wide variety of food items (omnivorous). Fourth-instar larvae are used by the colony to digest solid food and then regurgitate it for consumption by workers and queens. Larvae are an ideal source of investigations of endosymbiotic bacteria possibly involved in nutrient distributions. Our study utilized 16S rDNA sequencing to describe the composition of the bacterial community in fourth-instar ant larvae in order …

Race Differences In Activity, Fitness, And Bmi In Female Eighth Graders Categorized By Sports Participation Status, John R. Sirard, Karin A. Pfeiffer, Marsha Dowda, Russell R. Pate

Faculty Publications

The purpose of this study was to identify racial differences in physical activity (PA), fitness, and BMI in female 8th-grade sports participants and nonparticipants. Girls from 31 South Carolina middle schools (N=1,903, 48% White; mean age=13.6 ± 0.63) reported PA and previous year sports-team participation, completed a submaximal fitness test, and had height and weight measured. Sports team participation was positively associated with PA and negatively associated with television viewing and BMI, in a dose-response manner. Compared with Whites, African-Americans reported less PA and more television viewing, and had greater BMI scores. Whereas PA intervention programs that incorporate …

Sexual Harassment Experiences And Harmful Alcohol Use In A Military Sample: Differences In Gender And The Mediating Role Of Depression, Jaimie L. Gradus, Amy E. Street, Kacie Kelly, Jane Stafford

Faculty Publications

The current investigation identified the genderspecific prevalence of sexual harassment and assault experienced during U.S. military service and the negative mental and physical health correlates of these experiences in a sample of former reservists. We surveyed a stratified random sample of 3,946 former reservists about their experiences during military service and their current health, including depression, posttraumatic stress disorder, somatic symptoms, and medical conditions. Prevalence estimates and confidence intervals of sexual harassment and assault were calculated. A series of logistic regressions identified associations with health symptoms and conditions. Both men and women had a substantial prevalence of military sexual harassment …

Making The Implicit Explicit: Creating Performance Expectations For The Dissertation, Debra S. Gentry

Faculty Publications

No abstract provided.

Paripartum Cardiomyopathy: Implications For Nps, Jeffrey A. Goss, A. Elaine Bond, Renea L. Beckstrand, Lynn C. Callister

Faculty Publications

Peripartum cardiomyopathy (PPCM), the fifth leading cause of death in pregnancy, is often overlooked or misdiagnosed because of vague symptoms and a lack of specific criteria for diagnosis. The authors performed a literature review of articles published between January 2000 and November 2007, and found that early diagnosis via echocardiography and interventions with specific treatment modalities can reduce mortality. Dobutamine stress testing may be prognostic for left ventricular (LV) dysfunction. Standard heart failure (HF) drug regimens, heart transplantation, and mechanical assist devices are viable treatment modalities, depending on individual needs. Subsequent pregnancies must be followed closely. The authors recommend that …

Reducing Stray Radiation Dose To Patients Receiving Passively Scattered Proton Radiotherapy For Prostate Cancer, Phillip J. Taddei, Jonas D. Fontenot, Yuanshui Zheng, Dragan Mirkovic, Andrew K. Lee, Uwe Titt, Wayne D. Newhauser

Faculty Publications

Proton beam radiotherapy exposes healthy tissue to stray radiation emanating from the treatment unit and secondary radiation produced within the patient. These exposures provide no known benefit and may increase a patient's risk of developing a radiogenic second cancer. The aim of this study was to explore strategies to reduce stray radiation dose to a patient receiving a 76 Gy proton beam treatment for cancer of the prostate. The whole-body effective dose from stray radiation, E, was estimated using detailed Monte Carlo simulations of a passively scattered proton treatment unit and an anthropomorphic phantom. The predicted value of E was …

Gold Nanoparticle Sensor For Homocysteine Thiolactone-Induced Protein Modification, Arther T. Gates, Sayo O. Fakayode, Mark Lowry, Gabriela M. Ganea, Abitha Murugeshu, James W. Robinson, Robert M. Strongin, Isiah M. Warner

Faculty Publications

Homocysteine thiolactone-induced protein modification (HTPM) is a unique post-translational protein modification that is recognized as an emergent biomarker for cardiovascular disease. HTPM involves the site-specific acylation of proteins at lysine residues by homocysteine thiolactone (HTL) to produce protein homocystamide, which has been found at elevated levels in patients with coronary heart disease. Herein, we report the development of a novel gold nanoparticle (GNP) biochemical sensor for detection of protein homocystamide in an in vitro serum protein-based model system. Human serum albumin (HSA) and human sera were subjected to HTPM in vitro to produce HSA-homocystamide or serum protein homocystamide, respectively, which …

Obesity Reduction And Its Possible Consequences: What Can We Learn From Cuba's Special Period?, Manuel Franco, Pedro Orduñez, Benjamín Caballero, Richard S. Cooper

Faculty Publications

No abstract provided.

Yes/No Recognition, Forced-Choice Recognition, And The Human Hippocampus, P. J. Bayley, J. T. Wixted, Ramona O. Hopkins, L. R. Squire

Faculty Publications

Two recent studies reported that yes/no recognition can be more impaired by hippocampal lesions than forced-choice recognition when the targets and foils are highly similar. This finding has been taken in support of two fundamental proposals: (1) yes/no recognition tests depend more on recollection than do forced-choice tests; and (2) the hippocampus selectively supports the recollection process. Using the same stimulus materials as in the earlier studies, we tested five memory-impaired patients with circumscribed hippocampal lesions and 15 controls. As in the earlier studies, participants studied 12 pictures of objects and then took either a 12-item forced-choice test with four …

Effects Of Imperfect Dynamic Clamp: Computational And Experimental Results., Bettencourt Jc, Lillis Kp, Stupin Lr, White Ja

Faculty Publications

No abstract provided.

Artificial Synaptic Conductances Reduce Subthreshold Oscillations And Periodic Firing In Stellate Cells Of The Entorhinal Cortex., Fernandez Fr, White Ja

Faculty Publications

No abstract provided.

Seeing Inside The Mountains: Cynthia Rylant's Appalachian Literature And The "Hillbilly" Stereotype, Karen Roggenkamp

Faculty Publications

If Ob, as a West Virginia native, possesses the ability to see The Mysteries where others see only primitivistic whittling or, more pejoratively, tacky wooden trash cluttering the yards of mountain families, then Rylant's Appalachian works likewise depict characters who possess an ability to see beyond external markers and predictable interpretations, and who seek an emotional and spiritual interiority based on family, love, and sense of place. Rylant's words in The Relatives Came, When I Was Young in the Mountains, and Missing May work to restore the integrity of Appalachia as a place of "interior" values, a setting that symbolizes …

Four Lessons From The Whole Foods Case, Thom Lambert

Faculty Publications

One of the most maligned antitrust decisions in history involved a merger of grocery store chains. Indeed, even those voices inclined toward substantial antitrust intervention believe the U.S. Supreme Court erred in its 1966 Von's Grocery decision, which condemned the merger of the third- and sixth-largest grocery store chains in Los Angeles. For example, the president of the reliably interventionist American Antitrust Institute conceded that the Supreme Court "probably went too far" and acknowledged that "if Von's Grocery had remained the rule, all of our industries would be highly fragmented and consumers would have lost out on many cost-cutting efficiencies." …

The Effect Of Diets Varying In Dietary Cation-Anion Difference Fed In Late Gestation And In Lactation On Sow Productivity, M. L. Roux, S. L. Johnston, R. D. Lirette, T. D. Bidner, L. L. Southern, P. W. Jardon

Faculty Publications

© 2008 American Registry of Professional Animal Scientists. Eighty-six primiparous or multiparoussows and their pigs were used to evaluatethe effects of changing DCAD in late gestation and in lactation on sow productivity.Sows were allotted to treatment based on parity and their farrowing date. Experiment 1 was a preliminary experiment conducted to determine the level of DCAD that would reduce urinary pH. Twenty sows were used in Exp. 1, and the dietary treatments consisted of a corn-soybean meal diet with 4 levels of DCAD (140, 103, 80, and 56 mEq/kg). These DCAD were achieved by addition of 4 levels of chloride …

First Report Of Multiple Drug Resistance In Trichostrongyles Affecting Sheep Under Field Conditions In Italy (Parasitology Research (2007) 101, 6, (1713-1716) Doi: 10.1007/S00436-007-0707-4), Donato Traversa, Barbara Paoletti, Domenico Otranto, James Miller

Faculty Publications

No abstract provided.

Legal Theoretic Inadequacy And Obesity Epidemic Analysis, David Yosifon

Faculty Publications

This Article explores crucial analytic and normative limitations in presently dominant and ascendant approaches to legal theory. The approaches' failure to provide a satisfying framework for analyzing the obesity epidemic presently raging undeterred in American society reveals these limitations. Conventional law and economics scholars writing on the subject have deployed familiar frameworks to reach predictable conclusions that are neither intellectually nor morally justifiable. This Article argues that recent theoretical innovations promulgated within the burgeoning law and behavioralism movement have thus far provided no more reliable a framework for legal analysis of the obesity epidemic than has conventional law and economics. …

Trendspotting And Microtrends In Academic Libraries, Nicole A. Cooke, P. Hawthorne

Faculty Publications

No abstract provided.

Substantive Due Process Limits On Punitive Damage Awards: "Morals Without Technique"?, F. Patrick Hubbard

Faculty Publications

In a series of cases decided over the last two decades, the Supreme Court has used the Due Process Clause to establish a procedural and substantive framework for awarding punitive damages. Initially, the substantive aspects of this framework were sufficiently clear and flexible that they required little change in the system and probably generated a helpful level of debate and uniformity as to some basic requirements for awards. However, in BMW of North America, Inc. v. Gore, the Court adopted an approach characterized by a lack of clarity and consistency, an inadequate basis in theory and policy, and ad hoc …