Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Electronic Theses and Dissertations

Discipline
Institution
Keyword
Publication Year

Articles 871 - 900 of 11607

Full-Text Articles in Entire DC Network

Optimizing E-Payment Applications For Older Adults: User-Centered Solutions To Improve Security, Privacy, Usability, And Accessibility, Urvashi Kishnani Nov 2023

Optimizing E-Payment Applications For Older Adults: User-Centered Solutions To Improve Security, Privacy, Usability, And Accessibility, Urvashi Kishnani

Electronic Theses and Dissertations

In an increasingly digital world, older adults are rapidly becoming a vital demographic in the realm of electronic financial transactions. It is imperative to address their unique needs and challenges to ensure their financial well-being. Older adults can be more vulnerable to various online threats, making security and privacy paramount. As they adapt to the digital age, understanding their specific privacy concerns and preferences is crucial for creating trustworthy e-payment systems. Moreover, enhancing the usability of e-payment applications for older adults promotes financial independence and inclusion, contributing to their overall quality of life. By focusing on these critical dimensions, we …


The Impact Of Self-Compassion Strategies To Reduce Stress And Support The Transition To Practice For New Graduate Nurses: A Pilot Project, Charity Michelle Ballmann Nov 2023

The Impact Of Self-Compassion Strategies To Reduce Stress And Support The Transition To Practice For New Graduate Nurses: A Pilot Project, Charity Michelle Ballmann

Electronic Theses and Dissertations

Abstract The purpose of the study was to analyze the impact of self-compassion exercises to reduce stress and support the transition to practice for new graduate nurses. As the years pass, one thing remains a consistent topic in healthcare, and the need for nurses remains constant. The nursing staffing shortage gap seemingly widened further as the COVID-19 pandemic created additional challenges for healthcare systems, patient care, and employees. Retention of the workforce and an intentional focus on new graduate nurses' well-being have become increasingly important. New graduate nurses are a pipeline for the nursing workforce. Supporting the transition to practice …


Seeking Sisterhood: An Exploratory Qualitative Inquiry Into The Sorority Rejection Experiences Of Black Women, Jasmine Michelle Pulce Nov 2023

Seeking Sisterhood: An Exploratory Qualitative Inquiry Into The Sorority Rejection Experiences Of Black Women, Jasmine Michelle Pulce

Electronic Theses and Dissertations

In response to a call to fill the gap left by previous studies on collegiate sorority rejection, this study explored the meaning Black women ascribe to experiences of rejection from historically Black sororities. Using Black feminist thought and sista circle methodology, this study introduced narratives from five Black women who came together to comprise a collective standpoint. To better understand this phenomenon, study participants completed individual interviews, two Sista Circles, and one reflection survey. Three main findings were the interconnectedness of Black Greek-letter organizations and Black subcommunities at predominantly white institutions, the nonlinear nature of the Black sorority rejection experience, …


Assessment Of Self-Efficacy And Practice Change Following Pressure Injury Education In A Long-Term Care Facility, Charity L. Booker Nov 2023

Assessment Of Self-Efficacy And Practice Change Following Pressure Injury Education In A Long-Term Care Facility, Charity L. Booker

Electronic Theses and Dissertations

The purpose of this scholarly project was to evaluate if pressure injury education improved nursing knowledge and self-efficacy in the prevention and management of pressure injuries with the intent to improve practice. A literature review was conducted to evaluate educational interventions for adult learners and nursing roles in the care process. Existing studies indicated that patient outcomes are improved when nurses have adequate knowledge in pressure injury prevention. This quality improvement project was implemented in a long-term care facility with 28 nursing staff. The Agency for Healthcare Research and Quality pressure injury best practices presentation was the basis for the …


The Politics Of Preservation: Stewarding Artifacts In Archives, Kollynn Hendry Nov 2023

The Politics Of Preservation: Stewarding Artifacts In Archives, Kollynn Hendry

Electronic Theses and Dissertations

Kay Bailey Hutchison served Texas and the United States in many capacities during her political career. She vastly impacted Texas, as well as Nacogdoches, Texas in particular, through her time serving as a member of the Texas House of Representatives and as a United States Senator. In 2012, she donated her massive collection of gifts and memorabilia to the East Texas Research Center, a regional archive at Stephen F. Austin State University. The university honored her donation by creating a room to display the collection and interpret her influence on East Texas. Due to a rushed timeline, administrative interference, and …


Mothers In Law: A Critical Discourse Analysis Of Mothers In Law School, Sarah M. Jordon Nov 2023

Mothers In Law: A Critical Discourse Analysis Of Mothers In Law School, Sarah M. Jordon

Electronic Theses and Dissertations

Mothers are an increasing student population in higher education but an extensively under-researched population. While research examining motherhood is limited, the dearth of studies examining motherhood in higher education is especially limited, with even less available in the legal field and the institutions that provide legal education. This study examined how mothers in law school made meaning of their experiences utilizing a postmodernist epistemological framework, postmodernism and performance as a theoretical framework, and critical discourse analysis as a methodology. Data collection took place over the 2022-2023 academic year. Eight mothers participated in this qualitative study representing a range of ability …


Digital Twins Of The Living Knee: From Measurements To Model, Thor Erik Andreassen Nov 2023

Digital Twins Of The Living Knee: From Measurements To Model, Thor Erik Andreassen

Electronic Theses and Dissertations

Modern medicine has dramatically improved the lives of many. In orthopaedics, robotic surgery has given clinicians superior accuracy when performing interventions over conventional methods. Nevertheless, while these and many other methods are available to ensure treatments are performed successfully, far fewer methods exist to predict the proper treatment option for a given person. Clinicians are forced to categorize individuals, choosing the best treatment on “average.” However, many individuals differ significantly from the “average” person, for which many of these treatments are designed. Going forward, a method of testing, evaluating, and predicting different treatment options' short- and long-term effects on an …


Kinematic Analysis Of Gait And Deep Knee Flexion For Pre- And Post-Operative Total Knee Arthroplasty, Samantha Collins Nov 2023

Kinematic Analysis Of Gait And Deep Knee Flexion For Pre- And Post-Operative Total Knee Arthroplasty, Samantha Collins

Electronic Theses and Dissertations

Osteoarthritis (OA) is a form of arthritis that develops in the joint due to overuse and aging causing pain, discomfort, and disability. Total Knee Arthroplasty (TKA) is a surgical procedure performed when OA symptoms are severe with an estimated 600,000 patients in the United States currently receiving TKA. Studies have reported dissatisfaction of the knee for 14-39% of patients. This study collected knee kinematics before and after surgery using stereo radiography for precise measurement of gait and deep knee flexion activities. Results showed healthy knee kinematics were not restored and no significant changes could be seen from OA kinematics in …


Computational Methodology For Generating Patient-Specific Soft Tissue Representations, Ahilan Anantha Krishnan Nov 2023

Computational Methodology For Generating Patient-Specific Soft Tissue Representations, Ahilan Anantha Krishnan

Electronic Theses and Dissertations

This dissertation focused on modeling specimen-specific soft tissue structures in the context of joint replacement surgery. The research addressed four key aspects. The first study involved developing a workflow for creating finite element models of the hip capsule to replicate its torque-rotational response. Experimental data from ten cadaveric hips were used to calibrate the models, resulting in improved accuracy and relevance for surgical planning and implant design. The second study tackled the challenge of expediting the calibration of mechanical properties of the hip capsule to match patient-specific laxities. A statistical shape function model was proposed to generate patient-specific finite element …


Exploration Of Motion Capture System To Investigate Human Shoulder Kinematics, Ola Alsaadi Nov 2023

Exploration Of Motion Capture System To Investigate Human Shoulder Kinematics, Ola Alsaadi

Electronic Theses and Dissertations

The glenohumeral joint (GH) is commonly conceptualized as a ball-and-socket joint [1], and its center of rotation (COR) is presumed to coincide with the geometric center of the medial-superior region of the humeral head [2]. Recent research has endorsed improvements in COR estimation through invasive and noninvasive techniques, including cadaver studies, stereophotogrammetry, and motion capture (MOCAP) systems. Despite increased interest in wearable technology within human movement analysis, the problem of COR estimation employing MOCAP systems and its validation against bi-planar fluoroscopy remains relatively unexplored.

This study employed a marker-based MOCAP system to compare the accuracy, error, and precision of three …


An Educational Program To Improve African American Women’S Knowledge And Self Efficiency In Seeking Treatment For Endometrial Cancer, Lauren Elise Rosenthall Nov 2023

An Educational Program To Improve African American Women’S Knowledge And Self Efficiency In Seeking Treatment For Endometrial Cancer, Lauren Elise Rosenthall

Electronic Theses and Dissertations

In the United States, there is a significant difference in the survival rate for endometrial cancer for African American women when compared to women of other ethnic groups, specifically White women. There is supporting evidence that supports that morbidity and mortality rates for endometrial cancer increase if diagnosed in later stages. There are many contributing factors to a patient receiving an early diagnosis of a disease. One of the key determinants to early diagnosis of endometrial cancer is understanding risk factors, and what symptoms require further evaluation. An educational program was developed to identify knowledge deficits in the African American …


The Sustainability Of African American Female-Owned Businesses, Chantelle Daniel Thibeaux Nov 2023

The Sustainability Of African American Female-Owned Businesses, Chantelle Daniel Thibeaux

Electronic Theses and Dissertations

African American women–owned small businesses fail more often than non-Black-owned
businesses. The purpose of this phenomenological qualitative study was to describe successful
African American women small business owners’ leadership styles, traits, strategies, and
behaviors. Additionally, this study aimed to provide insights into specific leadership traits,
strategies, and behaviors that affect the sustainability of African American women–owned
businesses. Three leadership styles that have contributed to their business success were used to
frame this study: transformational, transactional, and situational leadership. All three of these
styles of leadership have been shown to help businesses succeed. Data were collected from
African American women business …


Is Conventional Colonoscopy More Effective Than Computed Tomography Colonography In The Screening Of Colorectal Cancer Among Young African American Adults?, Abena Abrafi Nimako Oct 2023

Is Conventional Colonoscopy More Effective Than Computed Tomography Colonography In The Screening Of Colorectal Cancer Among Young African American Adults?, Abena Abrafi Nimako

Electronic Theses and Dissertations

Healthcare journalist Brenda Goodman’s article on CNN Health on October 10, 2022, about a new study examining the effectiveness of colonoscopies, essentially concluded that the efficacy of conventional colonoscopy is in question. This research sought to establish whether conventional colonoscopy is more effective than computed tomography (CT) colonography in screening colorectal cancer among young African American adults. The researcher employed a literature review and a case-control research design to gather data on the subject. Data were collected from literature, the SEER database, the CDC, and the American Cancer Society websites. The study sample consisted of African Americans between the ages …


School Superintendents’ Perspectives Regarding Subordinates Developing, Utilizing, And Implementing Gifted Identification Equity, Vincent T. Landrum Oct 2023

School Superintendents’ Perspectives Regarding Subordinates Developing, Utilizing, And Implementing Gifted Identification Equity, Vincent T. Landrum

Electronic Theses and Dissertations

This study’s focus was the lived experiences of school superintendents about inconsistencies in gifted and talented education policy and ensuring the superintendents’ direct subordinates develop, utilize, and implement equitable gifted identification policies and practices, specifically for culturally, linguistically, and economically disadvantaged (CLED) students. Specifically, the researcher investigated the following: (a) the superintendents’ involvement in ensuring direct subordinates develop, utilize, and implement equitable gifted identification policies and practices for CLED students; (b) the superintendents’ involvement in ensuring their direct subordinates develop, utilize, and implement equitable gifted identification policies and practices for CLED students through professional development for those subordinates; and (c) …


Do Metrics Improve When Continuity Of Care Nurses Follow Chronic Disease Patients In The Ambulatory Setting?, Lura Cynthia Lunsford Sep 2023

Do Metrics Improve When Continuity Of Care Nurses Follow Chronic Disease Patients In The Ambulatory Setting?, Lura Cynthia Lunsford

Electronic Theses and Dissertations

Navigating the complex, fragmented U.S. healthcare system presents patient challenges that result in increased utilization and consequent increases in the cost of care. This program evaluation was conducted to determine the impact of ambulatory assigned continuity of care nurses (COCN) on patient outcomes in terms of length of stay, return visits to the emergency department, and readmissions to the hospital within 30 days of discharge. Between June 1, 2020, and May 31, 2022, there were 26,912 admissions with general risk scores between 1 and 100. Undersampling technique was conducted to create a 1:2 balance of 3,502 patients admitted with an …


Understanding Immigration-Based Intractable Conflict Behaviors Through The Lenses Of Social Identity And Emotions, Caryn Cade Moir Sep 2023

Understanding Immigration-Based Intractable Conflict Behaviors Through The Lenses Of Social Identity And Emotions, Caryn Cade Moir

Electronic Theses and Dissertations

The purpose of this post-intentional phenomenological study was to understand how participants experience social identity, emotions, and cognitive freezing in the context of immigration-based conflict. Immigration-based conflict in the United States exemplifies intractable conflict; it increases polarization, negative emotions, and intolerance among individuals in the United States. This study included action research; learning more about how participants experienced immigration-based conflict contributed knowledge that mediators can use to better serve parties in conflict, particularly during premediation interviews. The researcher used semistructured interviews to gather data from six participants. The data indicated that immigration-based conflict in the United States is consistent with …


Exploring Habits Of Well-Being Rooted In Resiliency Among Ministry Leaders Having Experienced A Leadership Transition Of Senior Pastor In The Church: A Case Study, Eric D. Willis Sep 2023

Exploring Habits Of Well-Being Rooted In Resiliency Among Ministry Leaders Having Experienced A Leadership Transition Of Senior Pastor In The Church: A Case Study, Eric D. Willis

Electronic Theses and Dissertations

This qualitative phenomenological single case study sought to understand potential influence of well-being and resilience of ministry leaders where an unplanned leadership transition had occurred. With an interest in personal well-being of ministry leaders, the researcher was curious how those who remained on church staff endured a 2-year period between the departure of one senior pastor and the hiring of a new senior pastor. Much of the existing research on church leadership transitions focused on the negative factors associated with failures. Generally, there is a lack of understanding of the positive influences of well-being and resiliency. The researcher sought to …


Mental Health Education For Nurses Caring For Adults With Severe Mental Illness, Juliet O. Onyia Sep 2023

Mental Health Education For Nurses Caring For Adults With Severe Mental Illness, Juliet O. Onyia

Electronic Theses and Dissertations

The focus of this study was on mental health education for nurses who care for adults with severe mental illness. Severe mental illness is rising, and nurses cannot adequately provide quality patient-centered care to the population due to poor knowledge. In this study, the knowledge and perceptions of mental illness and care among registered nurses in the community were assessed before and immediately after a mental illness educational session. A non-experimental quantitative descriptive study was conducted using convenience sampling in a home health setting. Dorothea Orem's self-care theory was the theoretical framework that guided the project. Instruments included the Mental …


Analyzing Pseudomonas Aeruginosa With Bacteriophage Tags Using Photoacoustic Flow Cytometry, Jennifer C. Schinke Aug 2023

Analyzing Pseudomonas Aeruginosa With Bacteriophage Tags Using Photoacoustic Flow Cytometry, Jennifer C. Schinke

Electronic Theses and Dissertations

The number of daily bacterial infections is climbing and the CDC explains that this is due to the antibiotic-resistant threat in the United States. Finding a faster way of bacterial identification is necessary as it currently takes 1-4 days for a medical lab to culture and identify bacteria. Photoacoustic flow cytometry (PAFC) can be used as an alternative method resulting in swift identification within an hour (Edgar, 2019). Pseudomonas aeruginosa, cell line PA01, will be coated in up to a few hundred red dyed phages making it detectible by the photoacoustic flow cytometry system. Bacteriophages (phages) are viruses that …


Equity Of Access To Higher Education: An Examination Of Racial Minority And Socioeconomic Status Student Enrollment Trends, Jason Stack Aug 2023

Equity Of Access To Higher Education: An Examination Of Racial Minority And Socioeconomic Status Student Enrollment Trends, Jason Stack

Electronic Theses and Dissertations

The purpose of this quantitative research study was to examine the enrollment trends of racial minority and low socioeconomic enrollment, and the equity of higher education access at a four-year private institution in western Pennsylvania. The study concentrated on two student populations over a five-year period at a four-year private institution in western Pennsylvania, enrolled and accepted but not enrolled students of various racial minorities and socioeconomic backgrounds. The research was informed by the theoretical frameworks of Human Capital Theory, Meritocracy Theory, and Net Price Theory. The research questions that guided the study were the following: What are the enrollment …


Examining School Nurses' Knowledge And Confidence Related To Their Intention To Screen For And Report Child Sexual Abuse: A Descriptive Cross-Sectional Study, Suzanne Ackers Aug 2023

Examining School Nurses' Knowledge And Confidence Related To Their Intention To Screen For And Report Child Sexual Abuse: A Descriptive Cross-Sectional Study, Suzanne Ackers

Electronic Theses and Dissertations

Background: Child sexual abuse (CSA) in a preventable national public health problem that results in adverse health consequences. Research suggests many victims are currently attending school. Screening for early detection of health issues is integral to school nurse (SN) practice but there is little evidence that screening for CSA is occurring in schools despite recommendations that it should be. Lack of confidence and knowledge related to screening for suspected CSA contribute to a SN’s missed opportunity for early intervention.

Purpose: To describe SNs knowledge and self-efficacy associated with screening for and reporting CSA in school settings.

Methods: A descriptive cross-sectional …


Examining The Effectiveness Of Using Point-Of-View Video Modeling On Mathematics Improvement In Students With Learning Disabilities In Saudi Arabia, Tirad Alsaluli Aug 2023

Examining The Effectiveness Of Using Point-Of-View Video Modeling On Mathematics Improvement In Students With Learning Disabilities In Saudi Arabia, Tirad Alsaluli

Electronic Theses and Dissertations

Video Modeling (VM) is one of the most widely used approaches by researchers to improve many skills, such as academic skills in students with Learning Disabilities (LD; Boon et al., 2020). As the incidence rate of individuals with LD in Saudi Arabia increase (Almedlij & Rubinstein-Ávila, 2018), the need for evidence-based math interventions focused on the math development of individuals with LD also increases. Although VM is recognized as an Evidence-based Practice (EBPs), a limited number of studies have implemented VM as an intervention to improve mathematic skills. Implementing VM as a math intervention strategy would explore its effects on …


The Significance Of A Minority Professional Development Internship Program: A Case Study Evaluation On African American/Black Males Career Trajectory At A Predominately White Institution, Marla Bradford Aug 2023

The Significance Of A Minority Professional Development Internship Program: A Case Study Evaluation On African American/Black Males Career Trajectory At A Predominately White Institution, Marla Bradford

Electronic Theses and Dissertations

This qualitative study aimed to investigate the significance of the Minority Professional Development Internship Program at a Predominately White Institution (PWI) of higher learning in southwestern Pennsylvania. The program was developed because many PWIs struggle to attract, recruit, and retain African Americans/Black and historically marginalized community members to lead their institutions in curriculum development, mentoring, recruitment, and governance (Reyes & Rios, 2005). Other research studies on African American/Black administrators’ lack of representation at PWIs attributed systemic barriers impeding their recruitment and advancement (Jones, 2007; Perna et al., 2007). Furthermore, Levin et al. (2013) suggest minimal progress in hiring African American/Black …


Spatial Structure Formation By The Post-Transcriptional Gene Regulator Rsme In Pseudomonas Fluorescens Pf0-1, Anton Evans Aug 2023

Spatial Structure Formation By The Post-Transcriptional Gene Regulator Rsme In Pseudomonas Fluorescens Pf0-1, Anton Evans

Electronic Theses and Dissertations

Microorganisms are often found in microbial communities we call biofilms. Organisms living in these crowded environments have significant evolutionary pressure to retain access to the resources necessary to sustain life. My research uses the bacterium Pseudomonas fluorescens Pf0-1 to study how organisms evolve strategies to solve this crowding problem as aging colonies repeatedly generate mutant patches. These mutants expand the reach of the colony resulting in decreased local density as they push themselves up to the resource rich surface. These spatial structures result from social interactions between the mutant and the parental cells mediated through extracellular secretions, resulting in the …


[3+2]-Cycloadditions Of Tertiary Amine N-Oxides And Dipolarophiles Providing An Efficient Route To Heterocyclics And 1,2-Diamines, And Nickel Catalayzed Transformations, Sarah Hejnosz Aug 2023

[3+2]-Cycloadditions Of Tertiary Amine N-Oxides And Dipolarophiles Providing An Efficient Route To Heterocyclics And 1,2-Diamines, And Nickel Catalayzed Transformations, Sarah Hejnosz

Electronic Theses and Dissertations

Nitrogen containing compounds are ubiquitous in nature as well as pharmaceuticals. These structures exhibit rich bioactive and chemical properties boasting an array of practical applications. As a result, the synthetic methods of forming nitrogen containing compounds are highly sought after. More efficient syntheses of these structures could result in less expensive industrial processes, particularly in the pharmaceutical industry. Roussi and coworkers established a highly efficient synthetic route forming nitrogen containing heterocycles in a single step from commercially available reagents, however this chemistry has not be used since its discovery in the 1980. Herein, this work greatly expanded Roussi’s method and …


Glycerophosphocholine Is Used For Lipid And Phosphate Metabolism By Candida Albicans, Will King Aug 2023

Glycerophosphocholine Is Used For Lipid And Phosphate Metabolism By Candida Albicans, Will King

Electronic Theses and Dissertations

The metabolism of phosphatidylcholine (PC), a major eukaryotic membrane lipid, has been shown to be an important aspect of pathogenesis in Candida albicans. Of note, PC turnover product, glycerophosphocholine (GPC), is abundant renal metabolite available within the host. GPC is readily imported by C. albicans, and deletion of the major GPC transporter, Git3, leads to decreased virulence in a bloodstream infection model. Here I have characterized two potential metabolic fates of internalized GPC. The first metabolic fate explored is internalized GPC can be hydrolyzed to release Pi. To determine if GPC import and subsequent metabolism impact phosphate …


Multiphasic Molecular Mechanisms Regulate Expression Of Interleukin 1Β, As Well As Other Immediate-Early Genes, In Monocytes And Macrophages, David Macar Aug 2023

Multiphasic Molecular Mechanisms Regulate Expression Of Interleukin 1Β, As Well As Other Immediate-Early Genes, In Monocytes And Macrophages, David Macar

Electronic Theses and Dissertations

Interleukin 1β (IL-1β), an important cytokine in both health and disease, functions as a major proinflammatory mediator of pathological challenges, including involvement in the cytokine storm associated with Macrophage Activation Syndrome, Hemophagocytic Lymphohistiocytosis and the severe secondary effects of SARS-CoV-2 infection. Therapeutic approaches to limiting the effects of IL-1β protein have focused either on specific protein neutralization before release from activated macrophages (by general metabolic inhibitors and inflammasome inhibition) or after release by ligand and receptor obstruction (e.g., Canakinumab, Anakinra and Rilonacept). Although these approaches are efficacious, they inhibit steps after gene expression. Since a single gene expresses …


Investigating The Impact On Private Water Supply Of Hydraulic Fracturing Communication With An Abandoned Conventional Gas Well In New Freeport, Pa, Kiley Miller Aug 2023

Investigating The Impact On Private Water Supply Of Hydraulic Fracturing Communication With An Abandoned Conventional Gas Well In New Freeport, Pa, Kiley Miller

Electronic Theses and Dissertations

In June of 2022 a “frac out” occurred in New Freeport, PA when an unconventional gas well under development by hydraulic fracturing, communicated with an abandoned gas well to the surface. An initial “zone of impact” encompassed much of the town’s main thoroughfare. Water samples were obtained from 17 private water wells, 5 springs and 1 pond (31 total samples) and analyzed for cations, anions, and light hydrocarbons. Methane was found in 18 of the samples, both located within and outside of the “zone of impact”. Mass ratio analyses indicated contamination from both unconventional and conventional wells. Interferometric Synthetic Aperture …


The Effects Of Transcranial Direct Current Stimulation (Tdcs) On Facial Expression Approach/Avoidance In College Students And Faculty With Broad Autism Phenotype, Nicole R. Baker Aug 2023

The Effects Of Transcranial Direct Current Stimulation (Tdcs) On Facial Expression Approach/Avoidance In College Students And Faculty With Broad Autism Phenotype, Nicole R. Baker

Electronic Theses and Dissertations

Transcranial Direct Current Stimulation (tDCS) has been proposed as an alternative noninvasive therapy for individuals with autism. This study trained brain activity in college students and / or faculty with Broad Autism Phenotype (BAP) while eye tracking data was collected. The purpose of this study was to determine if tDCS training to the frontal lobes could increase approach toward social interactions in adults classified as BAP as demonstrated by eye-tracking measures in response to faces and gaze fixation. The study included 21 total participants recruited from the Science, Technology, Engineering, and Math (STEM) courses / professions at a Regional East …


Development Of Air-Jetting System For Bioprinting Of Alginate Micro-Droplets, Nathan Lingenfelter Aug 2023

Development Of Air-Jetting System For Bioprinting Of Alginate Micro-Droplets, Nathan Lingenfelter

Electronic Theses and Dissertations

Transplantation of organoids has been demonstrated to be a promising cure to many diseases including Type-1 diabetes. However, achieving consistent and robust derivations of mature organoids from human pluripotent stem cells (hPSCs) is challenging. Cellular mechano-transduction, where mechanical stimuli is sensed and converted to biochemical signaling, has been proposed to overcome this challenge. This pathway relies on encapsulating hPSCs in a small volume of a biomaterial such as alginate, which has been widely used as cell encapsulation materials due to its biocompatibility and selective permeability. In this project, we focused on developing an air-jetting based technique to generate small and …