Digital Commons Network^™

A Phenomenological Inquiry Into Healthcare Professionals Who Are Experts In Cannabinoid Therapy And The Endocannabinoid System (Ecs), Courtney Collins

Electronic Theses and Dissertations

Cannabis is a prevalent alternative treatment for many symptoms and conditions given its medicinal qualities and few side effects. As legalization for both medical and recreational purposes continue to develop quickly across the United States of America, there is serious discrepancy between legalization and clinical research. Clinical data is difficult since the U.S. federal government still classifies cannabis as a Drug Enforcement Agency (DEA) Schedule I drug with no clearly established medical value. This lag in evidence-base data has affected cannabinoid therapy and endocannabinoid system education (ECS) for healthcare professionals. There are gaps in medical school and continuing medical education …

The Words. Or Holes. Or Both: Writing As An Integrative Methodology For Trauma, Daniel A. Castle

Electronic Theses and Dissertations

This project seeks to identify methods authors have used to integrate their traumatic experiences. My work will analyze the genre of War Literature and specific authors like J.R.R. Tolkien and Kurt Vonnegut to explore the way writers describe the trauma of combat. Using insights from neuroscience and psychology, I will expand the field of Cognitive Literary Studies from a focus on the reader to a focus on the writer by linking neurological functions with narrative tools.

Fatigue And Fracture Of Electron Beam Melting Ti-6al-4v, William A. Grell

Electronic Theses and Dissertations

For applications in the aerospace field, selection of materials for a given design requires an understanding of critical properties, like fatigue and fracture, in addition to static mechanical and physical properties. With the ongoing advancements in metallic additive manufacturing techniques and the interest in applying the process to aerospace applications, there is a clear need to fully characterize properties. Arguably, the most attractive alloy for applications in aerospace is the Ti-6Al-4V alloy. The current dissertation examines the mechanical properties of the alloy, made by the Electron Beam Melting (EBM) Powder Bed Fusion (PBF) method. As illustrated in this work, the …

Hemodynamic Assessment Of Y-Incision Aortic Root Enlargement Using Computational Simulations, Astitwa Ghimire

Electronic Theses and Dissertations

The Yang procedure is a new aortic root enlargement technique used to enlarge the aortic annulus by multiple valve sizes. The procedure prevents patient prosthesis mismatch and establishes a viable platform for future valve-in-valve implantation. This study used the Yang procedure to investigate the hemodynamics in the aortic root and bioprosthetic valve regions after aortic root enlargement. Results indicate the velocity magnitude at the sinus regions of a patient who underwent the Yang procedure was slower, indicating risks of flow stasis and thrombosis. Simulation results denote computational models can be created for optimization of surgical procedures.

Taiwanese International Students In Clinical Supervision: A Phenomenological Study, Joey Chiao-Yin Hsiao

Electronic Theses and Dissertations

The population of international students has continued to grow in the past two decades and become an important segment of U.S. university enrollment (Ng & Smith, 2001). Altogether, there is limited literature that is devoted to international students’ experience in clinical supervision and merely any international students studies specifically focused on the Taiwanese international student subgroup. This study examined the experiences of Taiwanese international students in clinical supervision. Interpretative Phenomenological Analysis (IPA) was used to extract the phenomenon of participants’ lifeworld and qualitative data were collected from individual semi-structured interviews with Taiwanese international students (N=6). Data analysis led to four …

Consensus-Based Active And Reactive Power Control And Management Of Microgrids, Shruti Singh

Electronic Theses and Dissertations

Microgrids incorporating distributed generation and renewable energy sources offer potential solutions to the energy crisis while modernizing traditional grids. Despite cost-effectiveness in some technologies, financial support remains crucial for expensive ones like PV, fuel cells, and storage technologies. Microgrids bring economic benefits, efficiency, reduced emissions, and improved power quality. Their success hinges on cost reductions in renewables, storage, reliability, and energy management systems, enabling operation both with and without the utility grid.

Economic Dispatch optimizes system costs, considering all constraints. Various methods tackle this problem, including quadratic convex functions, Lagrangian relaxation, and quadratic programming. For microgrids with distributed generators, seamless …

Controllable Language Generation Using Deep Learning, Rohola Zandie

Electronic Theses and Dissertations

The advent of deep neural networks has sparked a revolution in Artificial Intelligence (AI), notably with the creation of Transformer models like GPT-X and ChatGPT. These models have surpassed previous methods in various Natural Language Processing (NLP) tasks. As the NLP field evolves, there is a need to further understand and question the capabilities of these models. Text generation, a crucial part of NLP, remains an area where our comprehension is limited while being critical in research.

This dissertation focuses on the challenging problem of controlling the general behaviors of language models such as sentiment, topical focus, and logical reasoning. …

Do-It-Together: Informal Transformative Sustainability Education, Derek Brannon

Electronic Theses and Dissertations

The Climate Crisis is an urgent and inescapable reality students are thrust into. Learners must be prepared adequately for their futures, not only for their sakes but also because collective and transformative change is required. Transformative sustainability education provides one pathway to this transformation and focuses on radically altering students’ perceptions about the world and their agency in effecting change on ecological issues. The field of transformative sustainability education is emergent and thus is still fragmented, leaving gaps in the literature. Little research has been conducted on how informal and nonformal university spaces can be used to create transformative experiences …

Terrain And Adversary-Aware Autonomous Robot Navigation, Aniekan Ufot Inyang

Electronic Theses and Dissertations

In autonomous robot navigation, the robot is able to understand the environment around it for intelligent navigation. From its world model of this environment, it generates a global plan for navigation from a position to a goal based on different factors. This research aims to implement autonomous robot navigation by learning terrain affordances: traversability (moving quickly) and concealment (staying hidden from an adversary) using the Preference-based Inverse Reward Learning (PbIRL) methodology. The PbIRL methodology reduces the barrier of generating initial demonstration data to learn the terrain affordances by using a human expert’s preferences to learn individual weights over the terrain …

International Doctoral Student Experiences In Educational Administration Programs In The United States: A Phenomenological Study, Ping Robert

Electronic Theses and Dissertations

Background: In recent years, more international students are enrolling in Educational Administration (EA) programs in the United States. While EA programs wish to recruit and retain international students, more research is needed on supporting international graduate students in graduate education programs and EA programs specifically. Purpose: The present phenomenological study aims to understand the experience of international doctoral students in U.S. EA programs. The present research was guided by the question: “What is the essence of international postgraduate student experiences in EA programs in the United States?” Methodology: The present study used hermeneutic phenomenology to describe and interpret data from …

The Gender And Race Intersectional Disproportionality-Tool (Grid-T): An Exploration Of Practitioners’ Access To And Use Of High-Quality Data For Special Education Placement, Audrey J. Ford

Electronic Theses and Dissertations

Disproportionality in special education (SPED) is upheld by systems and individuals, policies, and practices that both reflect and shape the local communities within which it exists. Even with many proposed solutions for disproportionality, it persists. This two-manuscript dissertation explores two characteristics that make disproportionality difficult to solve (e.g., inconsistent findings and persistence) and proposes a tool to inform data-based decision making in interventions for disproportionality in SPED.

Manuscript One (M1) includes a literature review and development of the Gender and Race Intersectionality Disproportionality- Tool (GRID-T). Based on the findings of the literature review about inconsistence and persistence, I crafted three …

“Long Live Ear X-Tacy!”: An Oral History Study Of Rhetorics Of Nostalgia And Place., Aubrie Warner

Electronic Theses and Dissertations

This study aims to explore rhetorical placemaking through how people understand and construct narratives around places that no longer exist. In doing so, it examines the relationship between nostalgia and place — how rhetorical construction of place is influenced and/or informed by rhetorics of nostalgia, how our experiences influence our sense of place (past and present), and how we create continuity for ourselves in the construction and maintenance of particular narratives. This study contributes to the emerging field of rhetorics of nostalgia and places it in direct conversation with rhetorics of place and unpacks how these two are more connected …

A Machine Learning Approach To Constructing Ramsey Graphs Leads To The Trahtenbrot-Zykov Problem., Emily Hawboldt

Electronic Theses and Dissertations

Attempts at approaching the well-known and difficult problem of constructing Ramsey graphs via machine learning lead to another difficult problem posed by Zykov in 1963 (now commonly referred to as the Trahtenbrot-Zykov problem): For which graphs F does there exist some graph G such that the neighborhood of every vertex in G induces a subgraph isomorphic to F? Chapter 1 provides a brief introduction to graph theory. Chapter 2 introduces Ramsey theory for graphs. Chapter 3 details a reinforcement learning implementation for Ramsey graph construction. The implementation is based on board game software, specifically the AlphaZero program and its …

Evaluating Chatgpt For Recommendation: How Does The Ability To Converse Impact Recommendation?, Kyle Spurlock

Electronic Theses and Dissertations

Recommendation algorithms have become an absolute necessity in the modern world to avoid information overload. However, the interaction between the human and the system is largely superficial and without any real contact. If you are given poor recommendations, you have no choice but to sift through mountains of content on your own until the model learns to accommodate your tastes more. This is bad for business as well as the consumer. Recently, large language models like ChatGPT have seen a significant rise in popularity due to their ease of use and wide range of knowledge. It has now become nearly …

Development And Application Of A Microfluidic Platform For Quantifying Intra-Tumoral Compressive Stress., Zachary P. Fowler

Electronic Theses and Dissertations

Cancer progression is linked to the emergence of aberrant mechanical signaling in the tumor microenvironment. Modulation of extrinsic signals, such as ECM stiffness and composition, have been thoroughly explored. However, the development of solid stresses within the tumor remains poorly understood. To address this, we have developed a microfluidic platform that generates deformable alginate microbeads that allow for the quantification of compressive stresses generated within a growing glioblastoma (GBM) tumorsphere. PDMS microfluidic devices were fabricated via SU-8 mold with channels ranging from 10µm-40µm in diameter. Fluorescently labeled sodium alginate underwent a cross-linking reaction within the device to generate monodisperse beads …

Design And Evaluation Of A Multi-Functional Surgical Device For Microgravity Surgeries., Sienna Shacklette

Electronic Theses and Dissertations

No abstract provided.

Investigation Of Possible Inflammatory Response After Ultrasound And Microbubble Procedure In The Spinal Cord., Jenna Wilkerson

Electronic Theses and Dissertations

The purpose of this experiment is to explore the inflammatory effects of focused ultrasound paired with intravenously delivered microbubbles when used in the lumbar spinal cord. There are currently very few pharmaceuticals that can successfully enter the blood spinal cord barrier (BSCB). This technique used at the lumbar enlargement might allow targeted treatment of pathologies involving the spinal cord.

To test the possible inflammatory response of this technique, an animal experiment was performed. 15 animals were given a T12 laminectomy and allowed to fully recover. Once recovered, all animals received FUS+MB at L2 and were euthanized in groups of five …

Addition Of Process Control Experiment To Unit Operations Ii Laboratory., Bradley Esselman

Electronic Theses and Dissertations

Process control is an essential aspect of manufacturing, contributing to improved process safety, efficiency, product consistency, and energy optimization. Chemical engineers are often responsible for ensuring the safe, efficient, and cost-effective operation of industrial processes, and process control plays a pivotal role in accomplishing this.

Chemical engineering students at the University of Louisville complete the course, Elements of Process Control, during the second semester of their fourth year. This lecture-based course offers limited hands-on, practical experience. To supplement the lack of hands-on experience in the classroom, a new process control experiment was designed and implemented into the Unit Operations …

Insights Into The Structural And Electronic Properties Of 2d Polar Sic/Gec Heterostructures And Asxp1−X Alloys., Kazi Jannatul Tasnim

Electronic Theses and Dissertations

Due to the unique structural and electronic properties along with the practical applications in current and near future, investigations about the group-IV graphene-like two-dimensional (2D) sheets have been accelerated. Among them, 2D SiC and GeC sheets are polar materials with in-plane charge transfer from Si (Ge) to C atoms. An interesting question is how the electrostatic force, triggered by such in-plane charge transfer, plays a role in stabilizing the vertical heterostructures formed by 2D SiC and GeC sheets beyond vdW interaction. To answer this question, we have systematically investigated, in my PhD research projects, the effects of the electrostatic interaction …

Public Space And Well-Being: An Empirical Study Of Central Park In Old Louisville., Maryam Entezam

Electronic Theses and Dissertations

Urban green spaces have been receiving attention in urban planning and the health profession in the 21^st century as environmental elements that contribute to well-being. This dissertation explored the relationship between green space usage and individuals’ physical, mental, and social well-being. This empirical research focused on Central Park in Old Louisville to examine how residents use the park and whether it contributes to the well-being of residents. After exploring the existing literature, I identified four well-being indices: (1) perceived health (PHI), (2) health outcome (HOI), (3) mental well-being (MWI), and (4) social well-being (SWI). Frequent Park usage is expected …

Lightweight Blockchains And Their Network Impact On Vehicular Ad-Hoc Network-Based Blockchain Applications, Edgar Bowlin

Electronic Theses and Dissertations

Vehicular Ad-hoc Networks (VANETs) provide networks for smart vehicles and will enable future systems to provide services that enhance the overall transportation experience. However, these applications require consideration to possible damage to both property and human life. Communication between vehicles requires data immutability and user privacies to provide safe operation of the system. Blockchains can provide these properties and more to create a more secure and decentralized system. However, a chain’s security comes from the chain length. VANETs’ ephemeral connections provide harm limits how much data can be exchanged during vehicle rendezvous. This thesis investigates lightweight blockchains that operate with …

A Qualitative Content Analysis Of Nigerian Popular Music Genres: A Culture And Heritage Approach To Nation Branding, Cecilia Ashibel

Electronic Theses and Dissertations

This thesis explores the potential of Nigerian popular music as an approach to nation branding. The study employs qualitative content analysis to analyze select Nigerian music genres to examine how Nigeria is portrayed to international audiences and the economic benefits that can be derived from this form of branding. The analysis focuses on narrative themes of “the value of hard work,” “ethnic pride,” “lavish lifestyle,” and the impact of differences which were derived from the data. Findings indicate that Nigeria is globally reckoned for its musical prowess and rich cultural heritage. In highlighting the role of music in Nigeria’s political …

Characteristics Of Refractivity And Sea State In The Marine Atmospheric Surface Layer And Their Influence On X-Band Propagation, Douglas Matthew Pastore

Electronic Theses and Dissertations

Predictions of environmental conditions within the marine atmospheric surface layer (MASL) are important to X-band radar system performance. Anomalous propagation occurs in conditions of non-standard atmospheric refractivity, driven by the virtually permanent presence of evaporation ducts (ED) in marine environments. Evaporation ducts are commonly characterized by the evaporation duct height (EDH), evaporation duct strength, and the gradients below the EDH, known as the evaporation duct curvature. Refractivity, and subsequent features, are estimated in the MASL primarily using four methods: in-situ measurements, numerical weather and surface layer modeling, boundary layer theory, and inversion methods.

The existing refractivity estimation techniques often assume …

Visibility Based Hospital Inpatient Unit Design., Uttam Karki

Electronic Theses and Dissertations

Patient fall is one of the adverse events in an inpatient unit of a hospital that can lead to disability and/or mortality. Healthcare literature suggests that increased visibility of patients by unit nurses is essential to improve patient monitoring and, in turn, reduce falls. However, such research has been descriptive in nature and does not provide an understanding of the characteristics of an optimal inpatient unit layout from a visibility-standpoint. This dissertation fills significant voids in this domain and adds much-needed realism to develop insights that hospital decision-makers can use to design their inpatient unit layout. Our first contribution (Chapter …

Epitranscriptomic Regulation In Breast Cancer And Pcb-Induced Liver Disease., Belinda Petri

Electronic Theses and Dissertations

Post-transcriptional RNA modifications including N6-methyladenosine (m6A) regulate mRNA stability, splicing, and translation. My research examined m6A in two disease models: breast cancer (BCa) and non-alcoholic fatty liver disease (NAFLD). Acquired resistance to endocrine therapies (ET) develops in approximately 20% of BCa patients with estrogen receptor α positive (ER+) tumors following treatment. The mechanisms by which tumor cells evade ET are not completely understood. Using a cell line model, we investigated the role of an m6A reader protein, HNRNPA2B1 (A2B1) that is upregulated in ET-resistant ER+ BCa cells. Stable overexpression of A2B1 in ET-sensitive MCF-7 cells (MCF-7-A2B1), results in ET resistance, …

Measurement Of Conduction, Radiation, And Convection Thermal Energy To Assess Baking Performance In Residential Ovens., Sean Simpson

Electronic Theses and Dissertations

Residential ovens are complicated thermal environments capable of delivering convection, conduction, and radiation heat transfer to food. The amount and mode of heat transfer can change based on the design of the oven cavity, cooling systems, and oven cycle algorithms. Studies have shown that the changes in one heat transfer mode can have an impact on the quality of baked goods. The many variables involved make designing residential ovens a time consuming and costly process. The goal of this study is to adapt thermal energy sensing technology to collect energy data from a residential oven and develop correlations to quality …

Changes To Water Quality And Discharge In An Urban Stream In Southwest Jefferson County., Karina Henson

Electronic Theses and Dissertations

Mill Creek is the largest watershed in Southwest Jefferson County, where thousands of people live and work. Streams in the watershed have historically been channelized and altered to promote drainage, and stream health is of major concern. Louisville MSD is currently developing a watershed plan for Mill Creek by seeking understanding of current stream conditions. This paper will focus on historical trends in stream discharge and water quality. Peak and daily discharge, dissolved oxygen, specific conductance, and temperature data from USGS gages at Mill Creek and the Mill Creek Cutoff was analyzed to understand how water quality and flow rates …

Cannabidiol Tweet Miner: A Framework For Identifying Misinformation In Cbd Tweets., Jason Turner

Electronic Theses and Dissertations

As regulations surrounding cannabis continue to develop, the demand for cannabis-based products is on the rise. Despite not producing the psychoactive effects commonly associated with THC, products containing cannabidiol (CBD) have gained immense popularity in recent years as a potential treatment option for a range of conditions, particularly those associated with pain or sleep disorders. However, due to current federal policies, these products have yet to undergo comprehensive safety and efficacy testing. Fortunately, utilizing advanced natural language processing (NLP) techniques, data harvested from social networks have been employed to investigate various social trends within healthcare, such as disease tracking and …

Use Of Transposon Screening For Salicylic Acid-Assisted Desiccation Killing In Salmonella, Shannon D. Elliott

Electronic Theses and Dissertations

Salmonella enterica serovar Typhimurium is one of the most prevalent food-borne pathogens, affecting millions around the world every year, making it a threat to global health. Salmonella possesses the ability to survive the normally lethal condition of desiccation, however, discovery of the genes and mechanisms behind this phenomenon are still ongoing. Using a transposon mutagenesis approach to construct a broad transposon library, this study aimed to uncover genes that may be contributing to changes in Salmonella’s survivability under desiccation, particularly when exposed to the antimicrobial molecule salicylic acid. Building on previous findings showing salicylic acid can alter cell viability …

Comparison Of The 2022 Monkeypox (Mpox) Outbreak Using Mathematical Modeling And Time Series Clustering, Mark-Daniels Tamakloe

Electronic Theses and Dissertations

Monkeypox virus (MPXV) is the causative agent of monkeypox (mpox), a rare viral disease that affects humans [1]. It is primarily found in Africa and is transmitted to humans through contact with sick animals, particularly rodents and monkeys, or through human-to-human transmission [2]. From the beginning of May 2022, cases of mpox have been recorded from non-endemic nations, and the illness has continued to be reported in other endemic nations. Majority of confirmed cases have been recorded in Europe and North America. In this thesis, we compare the spread of the outbreak across the top ten countries using a combination …