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A Mechanism For Establishment And Maintenance Of The Meridional Overturning In The Upper Ocean, Timour Radko
A Mechanism For Establishment And Maintenance Of The Meridional Overturning In The Upper Ocean, Timour Radko
Journal of Marine Research
A two-dimensional analytical residual-mean model of the meridional overturning in the upper ocean is presented which illustrates dynamics of the interaction between the Northern and Southern hemispheres. The theory is based on the semi-adiabatic approximation in which all diabatic processes are confined to the upper mixed layer. The overturning circulation is driven directly by the wind forcing which, in our model, is affected by the sea-surface temperature distribution. The surface boundary conditions are symmetric with respect to the equator, and therefore one of the steady state solutions represents a symmetric flow characterized by the absence of the inter-hemispheric buoyancy fluxes. …
Equatorial Deep Jets Triggered By A Large Vertical Scale Variability Within The Western Boundary Layer, Marc D'Orgeville, Bach Lien Hua, Hideharu Sasaki
Equatorial Deep Jets Triggered By A Large Vertical Scale Variability Within The Western Boundary Layer, Marc D'Orgeville, Bach Lien Hua, Hideharu Sasaki
Journal of Marine Research
The response of the deep equatorial ocean to an oscillatory baroclinic western boundary current is investigated in a continuously stratified primitive equation model. The symmetry of the current about the equator is such that mixed Rossby-gravity (MRG) waves are excited in the western part of the equatorial ocean. Depending on the forcing frequency, short to long scale (when compared to equatorial Rossby radius) monochromatic MRG waves are selected. The subsequent MRG wave destabilization generally leads to a much higher vertical mode response than the forced MRG wave mode. In a channel, short MRG waves are destabilized by shear instability (Hua …
Mean Jets, Mesoscale Variability And Eddy Momentum Fluxes In The Surface Layer Of The Antarctic Circumpolar Current In Drake Passage, Y. D. Lenn, T. K. Chereskin, J. Sprintall, E. Firing
Mean Jets, Mesoscale Variability And Eddy Momentum Fluxes In The Surface Layer Of The Antarctic Circumpolar Current In Drake Passage, Y. D. Lenn, T. K. Chereskin, J. Sprintall, E. Firing
Journal of Marine Research
High-resolution Acoustic Doppler Current Profiler (ADCP) observations of surface-layer velocities in Drake Passage, comprising 128 sections over a period of 5 years, are used to study the surface-layer circulation of the Antarctic Circumpolar Current (ACC). These observations resolve details of the mean flow including the topographic control of the mean Subantarctic Front (SAF) and the multiple filaments of the Polar Front (PF) and Southern ACC Front (SACCF) that converge into single mean jets as the ACC flows through Drake Passage. Subsurface definitions of the SAF and PF applied to expendable bathythermograph temperatures generally coincide with mean jets, while the SACCF …
Plankton Accumulation And Transport In Propagating Nonlinear Internal Fronts, A. Scotti, J. Pineda
Plankton Accumulation And Transport In Propagating Nonlinear Internal Fronts, A. Scotti, J. Pineda
Journal of Marine Research
Accumulation and transport of plankton in fronts propagating across-shore is a process of considerable ecological importance for many inhabitants of the littoral zone, since it links the offshore larval pool with the juvenile and adult inshore habitat. Several field studies have shown that larval plankton accumulates in fronts, but have failed to give a conclusive proof that effective Lagrangian transport takes place. A few process-oriented numerical studies have lent support to the idea, but the scope of their results is limited by the two-dimensional nature of the flows considered and by the simple model used to account for the behavior …
Near-Bottom Horizontal Transfer Of Particulate Matter In The Palamós Submarine Canyon (Nw Mediterranean), J. Martin, A. Palanques, P. Puig
Near-Bottom Horizontal Transfer Of Particulate Matter In The Palamós Submarine Canyon (Nw Mediterranean), J. Martin, A. Palanques, P. Puig
Journal of Marine Research
From March to November 2001, six current meters equipped with turbidimeters were moored 12 meters above the bottom inside the Palamós submarine canyon and on the adjacent slope. Horizontal particle fluxes were calculated from current and suspended sediment concentration data. This work aims to evaluate the advective sediment fluxes taking place in the Palamós canyon region, and to discern the nature and time-scales of the processes involved in the across-margin transfer of particles over the study period. Near-bottom currents inside the canyon were constrained by the local topography and displayed a high spatio-temporal variability. The net near-bottom transport of suspended …
Simulations Of Phytoplankton Species And Carbon Production In The Equatorial Pacific Ocean 1. Model Configuration And Ecosystem Dynamics, Baris Salihoglu, Eileen E. Hofmann
Simulations Of Phytoplankton Species And Carbon Production In The Equatorial Pacific Ocean 1. Model Configuration And Ecosystem Dynamics, Baris Salihoglu, Eileen E. Hofmann
Journal of Marine Research
The primary objective of this research is to investigate phytoplankton community response to variations in physical forcing and biological processes in the Cold Tongue region of the equatorial Pacific Ocean at 0N, 140W. This research objective was addressed using a one-dimensional multicomponent lower trophic level ecosystem model that includes detailed algal physiology, such as spectrally-dependent photosynthetic processes and iron limitation on algal growth. The ecosystem model is forced by a one-year (1992) time series of spectrally-dependent light, temperature, and water column mixing obtained from a Tropical Atmosphere-Ocean (TAO) Array mooring. Autotrophic growth is represented by five algal groups, which have …
Influence Of Environmental Forcings On The Seasonality Of Dissolved Oxygen And Nutrients In The Bay Of Bengal, S. Sardessai, N. Ramaiah, S. Prasanna Kumar, S. N. De Sousa
Influence Of Environmental Forcings On The Seasonality Of Dissolved Oxygen And Nutrients In The Bay Of Bengal, S. Sardessai, N. Ramaiah, S. Prasanna Kumar, S. N. De Sousa
Journal of Marine Research
Studies on seasonal variability of oxygen and nutrients during three seasons namely SW monsoon, fall intermonsoon and spring intermonsoon indicate influence of physical forcings on the distribution of these hydrochemical properties in the subsurface layer. In the open ocean the Minimum Oxygen Layer (MOL ≤10 mu Mol L-1) during the southwest monsoon and fall intermonsoon is mostly confined to the north of 11N due to the penetration of high salinity water in the deeper waters of the central Bay. During spring intermonsoon MOL is mostly confined to the northern region between 14 to 20N with a narrow band …
A Fast Numerical Solution To The General Mass-Conservation Equation For Solutes And Solids In Aquatic Sediments, Peter Berg, Dennis Swaney, Søren Rysgaard, Bo Thamdrup, Henrik Fossing
A Fast Numerical Solution To The General Mass-Conservation Equation For Solutes And Solids In Aquatic Sediments, Peter Berg, Dennis Swaney, Søren Rysgaard, Bo Thamdrup, Henrik Fossing
Journal of Marine Research
Mathematical modeling of species transformations in aquatic sediments is usually based on numerical solutions to the same general one-dimensional mass-conservation equation and is likely to require substantial computation time. In this paper we present a fast numerical solution to this equation. The solution is suited for both single and multi-component models and it is based on an implicit control volume discretization of the general mass-conservation equation. The solution consists of two algorithms, one that decomposes the discretization matrix once and one that subsequently produces multiple solutions with minimal computational effort. A unique feature of these algorithms is that values of …
An Assessment Of The Use Of Sediment Traps For Estimating Upper Ocean Particle Fluxes, Ken O. Buesseler, Avan N. Antia, Min Chen, Scott W. Fowler, Wilford D. Gardner, Orjan Gustafsson, Koh Harada, Anthony F. Michaels, Michiel Rutgers Van Der Loeff, Manmohan Sarin, Deborah K. Steinberg, Thomas Trull
An Assessment Of The Use Of Sediment Traps For Estimating Upper Ocean Particle Fluxes, Ken O. Buesseler, Avan N. Antia, Min Chen, Scott W. Fowler, Wilford D. Gardner, Orjan Gustafsson, Koh Harada, Anthony F. Michaels, Michiel Rutgers Van Der Loeff, Manmohan Sarin, Deborah K. Steinberg, Thomas Trull
Journal of Marine Research
This review provides an assessment of sediment trap accuracy issues by gathering data to address trap hydrodynamics, the problem of zooplankton "swimmers," and the solubilization of material after collection. For each topic, the problem is identified, its magnitude and causes reviewed using selected examples, and an update on methods to correct for the potential bias or minimize the problem using new technologies is presented. To minimize hydrodynamic biases due to flow over the trap mouth, the use of neutrally buoyant sediment traps is encouraged. The influence of swimmers is best minimized using traps that limit zooplankton access to the sample …
Mismatch Between Community Respiration And The Contribution Of Heterotrophic Bacteria In The Ne Atlantic Open Ocean: What Causes High Respiration In Oligotrophic Waters?, Xosé Anxelu G. Morán, Valesca Pérez, Emilio Fernández
Mismatch Between Community Respiration And The Contribution Of Heterotrophic Bacteria In The Ne Atlantic Open Ocean: What Causes High Respiration In Oligotrophic Waters?, Xosé Anxelu G. Morán, Valesca Pérez, Emilio Fernández
Journal of Marine Research
Heterotrophic bacteria have long been considered as the major respirers of the open ocean. During a survey in the eastern N Atlantic Subtropical Gyre we measured 3H-leucine heterotrophic bacterial production (BP), 14C particulate primary production (PPP) and the O2 community metabolism rates: gross primary production (GPP), net community production (NCP) and community respiration (CR). We estimated heterotrophic bacterial respiration (BR) from BP and literature models of bacterial growth efficiency [BGE = BP/(BP + BR)]. BP was an order of magnitude lower than PPP (integrated means of 17 ± 2 and 207 ± 29 mg C m−2 …
Hurricane-Induced Destratification And Restratification In A Partially-Mixed Estuary, Ming Li, Liejun Zhong, William C. Boicourt, Shunli Zhang, Da-Lin Zhang
Hurricane-Induced Destratification And Restratification In A Partially-Mixed Estuary, Ming Li, Liejun Zhong, William C. Boicourt, Shunli Zhang, Da-Lin Zhang
Journal of Marine Research
Hurricane Isabel made landfall at the Outer Banks of North Carolina and moved past Chesapeake Bay on 18 –19 September 2003. The baroclinic response of this partially-mixed estuary to the passage of Isabel is investigated using the output from a regional atmosphere-ocean model. The hurricane-forced winds caused gradual deepening of the surface mixed layer, followed by rapid destratification in the water-column. The mixed-layer deepening appears to be driven by velocity shear and can be interpreted by a gradient Richardson number. Although strong winds caused complete mixing locally, a large longitudinal salinity gradient of about 10-4 psu m-1 persisted …
The Variability And Heat Budget Of The Upper Ocean Under The Chile-Peru Stratus, Keir Colbo, Robert Weller
The Variability And Heat Budget Of The Upper Ocean Under The Chile-Peru Stratus, Keir Colbo, Robert Weller
Journal of Marine Research
The persistent stratus clouds found west of Chile and Peru are important for the coupling of the ocean and atmosphere in the eastern Pacific and thus in the climate of the region. The relatively cool sea-surface temperatures found west of Peru and northern Chile are believed to play a role in maintaining the stratus clouds over the region. In October 2000 a buoy was deployed at 20S, 85W, a site near the center of the stratus region, in order to examine the variability of sea-surface temperature and the temporal evolution of the vertical structure of the upper ocean. The buoy …
Simulated Fiddler-Crab Sediment Mixing, Katherine Huang, Bernard P. Boudreau, Daniel C. Reed
Simulated Fiddler-Crab Sediment Mixing, Katherine Huang, Bernard P. Boudreau, Daniel C. Reed
Journal of Marine Research
Using a lattice-automaton model, we simulate the effects of fiddler crabs on the distribution of excess 210Pb in marsh sediments. Three previously-identified modes of bioturbation are investigated: (1) removal-and-fill, where material is excavated to the sediment-water interface and burrows, when abandoned, are subsequently filled by surface material, (2) removal-and-collapse, where the infilling occurs by collapse of the burrow walls, and (3) partial-compaction-and-collapse, where part of the excavated sediment is packed into the burrow wall and abandoned burrows subsequently collapse. These various mixing modes lead to somewhat different laterally-integrated 210Pbex profiles, which are also influenced …
Field Investigation On Seawater Temperature Variability In Relation To Horizontal Optical Gradient, Maciej Matciak, Bozena Wojtasiewicz
Field Investigation On Seawater Temperature Variability In Relation To Horizontal Optical Gradient, Maciej Matciak, Bozena Wojtasiewicz
Journal of Marine Research
The spatial variability of radiant energy absorption in seawater can result from the non-homogeneity of the concentration of its optically active components, such as chlorophyll or dissolved organic matter. This non-homogeneity leads to local changes in the radiant heating rate and consequent changes in water temperature. Besides a simple dependence, for instance when a higher phytoplankton concentration is accompanied by a temperature rise, a relation that is more complex may occur. A theoretical analysis suggested that sufficiently strong horizontal changes in seawater absorption may cause, in their close proximity, an additional increase or decrease in the heating rate. To confirm …
Thermohaline Structure And Variability In The Eastern Nansen Basin As Seen From Historical Data, David Walsh, Igor Polyakov, Leonid Timokhov, Eddy Carmack
Thermohaline Structure And Variability In The Eastern Nansen Basin As Seen From Historical Data, David Walsh, Igor Polyakov, Leonid Timokhov, Eddy Carmack
Journal of Marine Research
Newly available historical Russian data are used to quantify year-to-year variations in the structure and properties of the halocline and Atlantic Water layers in the eastern Nansen Basin. The data come from a series of aerial surveys of the central Arctic Ocean done during winter between 1973 and 1979, and repeated "Polygon" surveys of the shelf, slope, and basin north of Severnaya Zemlya in the 1980s, and thus allow a perspective on shelf-basin exchange. A water-mass census shows substantial survey-to-survey variability in several water-mass categories, with volumetric fluctuations of ∼17% in the Upper Polar Deep Water category, ∼14% in Atlantic …
Spatial Continuity Of Measured Seawater And Tracer Fluxes Through Nares Strait, A Dynamically Wide Channel Bordering The Canadian Archipelago, Andreas Münchow, Kelly K. Falkner, Humfrey Melling
Spatial Continuity Of Measured Seawater And Tracer Fluxes Through Nares Strait, A Dynamically Wide Channel Bordering The Canadian Archipelago, Andreas Münchow, Kelly K. Falkner, Humfrey Melling
Journal of Marine Research
Freshwater delivered as precipitation and runoff to the North Pacific and Arctic oceans returns to the Atlantic principally via the Canadian polar shelf and Fram Strait. It is conveyed as ice or freshened seawater. Here we use detailed ship-based measurements to calculate a snap-shot of volume, freshwater, and tracer fluxes through Nares Strait, a 500-km long waterway separating Greenland and Ellesmere Island. We use quasi-synoptic observations of current by ship-mounted acoustic Doppler current profiler (ADCP), of salinity and temperature by CTD probe and of dissolved nutrients by rosette bottle sampler on four cross-sections between 82 and 78N latitude. Data were …
Stigma Perceived By Persons With Human Immunodeficiency Virus Attending The Infectious Diseases Clinic Of Centre Hospitalier Universitaire De Fann In Dakar, Senegal, Nana Akua Asafu-Agyei
Stigma Perceived By Persons With Human Immunodeficiency Virus Attending The Infectious Diseases Clinic Of Centre Hospitalier Universitaire De Fann In Dakar, Senegal, Nana Akua Asafu-Agyei
Yale Medicine Thesis Digital Library
Human Immunodeficiency Virus (HIV)-associated stigma is pervasive throughout the world. This stigma affects the ability of HIV-positive individuals to cope with their illness and it also affects behaviors around sexual practices, disclosure to others and the use of healthcare. The purpose of the research project was to examine the experience of internalized stigma among HIV-positive persons and their perceptions of stigmatizing attitudes in the community. The study also examined disclosure of HIV serostatus and identified factors contributing to disclosure and stigma in Senegal, a low prevalence Muslim country in West Africa. A cross-sectional study was conducted at Centre Hospitalier Universitaire …
The Role Of Westward Intensification In Potential Vorticity Homogenization, Toshihiro Sakamoto
The Role Of Westward Intensification In Potential Vorticity Homogenization, Toshihiro Sakamoto
Journal of Marine Research
Using a two-layer quasigeostrophic model with weak interfacial and bottom friction we propose a mechanism for potential vorticity homogenization in a non-eddying, wind-driven gyre closed through a viscous western boundary layer, to which the previous theory based on the Prandtl–Batchelor theorem cannot be applied. It is shown that there exist steady states in which the lower-layer potential vorticity in a large pool of closed geostrophic contours becomes substantially uniform. The homogenization process is dominated by advection and thus completed within a single passage through the gyre. This is because an O (1) anomaly of potential vorticity that is comparable to …
Dissipation In Hydraulic Transitions In Flows Through Abyssal Channels, S. A. Thorpe
Dissipation In Hydraulic Transitions In Flows Through Abyssal Channels, S. A. Thorpe
Journal of Marine Research
There is growing evidence from observations that mixing occurs in hydraulic jumps, or flow transitions, downstream of sills within channels connecting deep ocean basins or within submarine canyons on the flanks of mid-ocean ridges. Models with continuous profiles of velocity and density upstream and downstream of a transition, but conforming to continuity conditions, are devised to represent the mixing that occurs in a hydraulic jump in a stratified shear flow of finite depth moving over a horizontal boundary in a deep fluid. These are used to assess the conditions in which transitions may occur and to provide an estimate of …
Oxygen And Nitrogen Cycling In The Northeast Pacific – Simulations And Observations At Station Papa In 2003/2004, N. Steiner, S. Vagle, K. Denman, C. Mcneil
Oxygen And Nitrogen Cycling In The Northeast Pacific – Simulations And Observations At Station Papa In 2003/2004, N. Steiner, S. Vagle, K. Denman, C. Mcneil
Journal of Marine Research
A long-term air-sea exchange mooring has been maintained in the North Pacific near Ocean Station Papa (OSP, 145W, 50N) since September 2002 as part of the Canadian Surface Ocean Lower Atmosphere Study (C-SOLAS). The mooring provides a new long-term data set for gas measurements. In addition to Conductivity, Temperature and Depth (CTD) recorders at two depths, the mooring is equipped with ProOceanus Gas Tension Devices (GTDs) measuring the total gas pressure at four different depths, two oxygen sensors, two fluorometers for chlorophyll estimates, and an upward-looking 200 kHz echo-sounder for bubble measurements. Chlorophyll data have been added using SeaWiFS imagery …
Phytoplankton Pigment Distribution In The Northwestern Alboran Sea And Meteorological Forcing: A Remote Sensing Study, D. Macías, G. Navarro, F. Echevarría, C. M. García, J. L. Cueto
Phytoplankton Pigment Distribution In The Northwestern Alboran Sea And Meteorological Forcing: A Remote Sensing Study, D. Macías, G. Navarro, F. Echevarría, C. M. García, J. L. Cueto
Journal of Marine Research
A set of weekly-composite SeaWiFS (Sea-viewing Wide Field of view Sensor) imagery (from 1998 to 2004) has been used to asses the temporal and spatial variability of the surface chlorophyll distribution in the Northwestern Alboran Sea. Empirical Orthogonal Function (EOF) analysis of the images series shows the existence of three different regions in which surface chlorophyll presents a homogeneous temporal behavior in the neighborhood of the Strait of Gibraltar.The temporal patterns of surface chlorophyll concentrations in each region have been characterized by studying the role of several forcing factors, mainly the zonal component of the wind field.The first identified region …
The Geography Of Linear Baroclinic Instability In Earth’S Oceans, K. Shafer Smith
The Geography Of Linear Baroclinic Instability In Earth’S Oceans, K. Shafer Smith
Journal of Marine Research
Satellite observations reveal a mesoscale oceanic circulation dominated by turbulence that is correlated, in most cases, with local baroclinicity. Linear baroclinic instability theory has proved useful in understanding the time and space scales of atmospheric eddies. The question addressed here is, to what degree can the observed oceanic eddy activity be understood through a local, linear stability analysis? This question is addressed as follows. A local quasigeostrophic linear stability calculation is performed on a grid of wavenumbers, ranging in magnitude about the local deformation wavenumber, for each vertical profile in a dataset of neutral density for the world's oceans. The …
Transient Tracer Dynamics In A Lattice-Automaton Model Of Bioturbation, Daniel C. Reed, Bernard P. Boudreau, Katherine Huang
Transient Tracer Dynamics In A Lattice-Automaton Model Of Bioturbation, Daniel C. Reed, Bernard P. Boudreau, Katherine Huang
Journal of Marine Research
Mixing of sediments by benthic fauna represents a dominant transport process of solids in the majority of surficial marine deposits. Short-term mixing rates are often determined by fitting a transient, diffusive model of bioturbation to vertical profiles of introduced particles (e.g., luminophores). Previous field studies adopting this approach have noted that mixing intensity decreases with time and the nature of mixing progresses from advective or nonlocal transport to diffusive mixing. These observations have been attributed to "age-dependent" mixing. The present study employs a lattice-automaton model to investigate the short-term behavior of conservative transient tracers. Simulations demonstrate that despite constant, indiscriminate …
Effects Of The New Histone Deacetylase Inhibitor Pxd101 In Bladder Cancer, Hristos Zacharias Kaimakliotis
Effects Of The New Histone Deacetylase Inhibitor Pxd101 In Bladder Cancer, Hristos Zacharias Kaimakliotis
Yale Medicine Thesis Digital Library
Histone deacetylase inhibitors (HDACIs) mediate gene expression and chromatin assembly, and induce growth arrest and apoptosis of tumor cells, thus representing a new strategy for human cancer therapy. Changes in apoptosis signaling pathways and the effect on cell growth and cell-cycle arrest of a new HDACI, PXD101, on T-24 bladder cancer cells form the basis of this study. T-24 cells were incubated with PXD101 at varying concentrations and times, and viable cell count and proliferation curves were constructed. Cell cycle analysis was conducted with Fluorescent Activated Cell Sorting and changes in apoptosis signaling proteins that were previously found to be …
On The Vorticity Cycle Of The Loop Current, A. Lugo-Fernández, A. Badan
On The Vorticity Cycle Of The Loop Current, A. Lugo-Fernández, A. Badan
Journal of Marine Research
The inrushing/retraction behavior of the Loop Current (LC) in the eastern Gulf of Mexico can be represented by a recurrent cycle of vorticity input/output with a time scale of 0 to 16 months. This cycle is brought about as a balance between the accumulation of absolute vorticity in the LC and deep advection of vorticity to the Caribbean Sea. The vorticity time scale is directly proportional to the change in circulation around the LC and 2πH/Q0(f0 + ζ0); where H (∼800 m) is the thickness of the LC, Q0 is …
The Enso Signature In Sea-Surface Temperature In The Gulf Of California, Hugo Herrera-Cervantes, Daniel B. Lluch-Cota, Salvador E. Lluch-Cota, Guillermo Gutiérrez-De-Velasco S
The Enso Signature In Sea-Surface Temperature In The Gulf Of California, Hugo Herrera-Cervantes, Daniel B. Lluch-Cota, Salvador E. Lluch-Cota, Guillermo Gutiérrez-De-Velasco S
Journal of Marine Research
We analyzed 21 years of sea-surface temperature satellite images to explore the spatial signature of the El Niño-Southern Oscillation signal in the Gulf of California. We used empirical orthogonal function analysis to extract the principal mode of the nonseasonal sea-surface temperature variability and compared it to the spatial signature of the Southern Oscillation Index. The first mode accounted for 80% of nonseasonal variability and its amplitude time series was significantly correlated to the Southern Oscillation Index (r = −0.58,P < 0.01). The amplitude of this mode and its statistical relation to the El Niño is stronger during winter, which suggests that forcing of sea-surface temperature variability occurs through the disruption of the wind-driven upwelling corridor along the eastern coast due to El Niño-related atmospheric teleconnections. We also examined weekly time series of coastal sea-surface temperature coastal anomalies along the coast of North America, including the interior of the Gulf of California, during the strong 1997–98 El Niño. We found a poleward propagating signal that reached the mouth of the Gulf of California at the end of spring and continued its poleward propagation along the west coast of the peninsula slightly delayed; it also resulted in warming inside the Gulf of California. This observation may provide an explanation for the variable extension of the El Niño signature along the Pacific coast of North America.
Water Column Stability And Spring Bloom Dynamics In The Gulf Of Alaska, Stephanie A. Henson
Water Column Stability And Spring Bloom Dynamics In The Gulf Of Alaska, Stephanie A. Henson
Journal of Marine Research
The initiation of the Gulf of Alaska phytoplankton spring bloom is light limited, and therefore the onset of stratification is critical to primary productivity. A stability ratio, which represents the balance between mixing (tide and wind) and buoyancy (heat and freshwater) processes, is defined. When buoyancy dominates over mixing, stratification is possible. Use of model- and satellite-derived data allows maps of the spatial and temporal development of stratification to be constructed. Spatial variability in the dominant forcing components is also mapped. The onset of water column stability is closely linked to the timing of the phytoplankton spring bloom. Consideration of …
Medicine@Yale September/October 2007 Volume 3, Issue 5, Yale School Of Medicine Office Of Communications
Medicine@Yale September/October 2007 Volume 3, Issue 5, Yale School Of Medicine Office Of Communications
Medicine@Yale - development newsletter
Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.
Medicine@Yale November/December 2007 Volume 3, Issue 6, Yale School Of Medicine Office Of Communications
Medicine@Yale November/December 2007 Volume 3, Issue 6, Yale School Of Medicine Office Of Communications
Medicine@Yale - development newsletter
Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.
Gene Expression Patterns In Patients With High-Altitude Pulmonary Edema: A Gene Microarray Analysis, Lauren Kendall Krause
Gene Expression Patterns In Patients With High-Altitude Pulmonary Edema: A Gene Microarray Analysis, Lauren Kendall Krause
Yale Medicine Thesis Digital Library
Multiple modulating genes and environmental factors have been implicated in the pathogenesis of high-altitude pulmonary edema (HAPE). However, at the present time, there exists an incomplete understanding of the molecular mechanisms and pathways which underlie constitutional susceptibility. Genome-wide measurements of gene expression in peripheral blood mononuclear cells (PBMCs) were performed using microarray technology. Comparison of gene expression profiles of HAPE-susceptible and resistant individuals resulted in the identification of several previously undescribed candidate genes. RhoA and Rho-kinase (ROCK), regulators of vascular smooth muscle contraction, were differentially regulated in the HAPE-susceptible cohort, as compared to both HAPE-resistant patients with acute mountain sickness …