Digital Commons Network^™

Dxa Body Composition Is Weakly Related To Blood Lipids, Blood Pressure, And Glucose In Firefighters, Kalen A. Johnson

International Journal of Exercise Science: Conference Proceedings

Current published data are inconclusive regarding whether DXA body composition measures of fat, lean, and regional fat mass are predictive of other CVD risk factors. PURPOSE: To determine if DXA measures can be used in a cardiovascular risk-predictive manner to indicate unhealthy levels of circulating lipoproteins in firefighters. METHODS: 256 male firefighters (age=35±10; ht=179±6.6 cm; wt=94±16 kg; BMI=29.9±4.6; fat mass=27.5±10.4 kg; lean mass=63±7.5 kg; gynoid%fat=28.7±6.5%; android%fat=36±11.3%; glucose=85±12.9 mg/dL; SBP=128±9 mmHg) underwent an annual cardiovascular risk profile screening and DXA scan; resting BP was also measured. We drew fasting blood samples, analyzed by a clinically certified lab, to determine glucose, HDL, …

Physician Assistant Students’ Perceptions Of The Fitness Industry And Lifestyle Medicine, Alyssa Abreu, Sarah-Ann Keyes, Mark Faries

International Journal of Exercise Science: Conference Proceedings

With nearly two-thirds of all chronic disease having a lifestyle cause, there is spurred interest in curricular changes for Physician Assistants (PA) and other medical providers to learn Lifestyle Medicine (LM) - the therapeutic use of lifestyle changes to prevent, treat and reverse disease. A key competency in LM practice involves an interdisciplinary approach, including aid from fitness professionals. Yet, perceptions of the fitness industry might hinder such a relationship. PURPOSE: To assess PA students' knowledge of LM and perceptions of the fitness industry, to guide curriculum implementation efforts. METHODS: An online survey was advertised to all PA students at …

Dexa Body Composition And Cardiovascular Risk Factors Weakly Related In Police Officers, Alison Mcguire, Stephen F. Crouse, Steven E. Martin, Allison Donnell, Daniel Mohnke, John S. Green Ph.D.

International Journal of Exercise Science: Conference Proceedings

There is currently little research on whether fat mass and distribution is a predictive factor of cardiovascular risk. PURPOSE: To determine if obesity measures, such as fat mass and distribution (android vs gynoid), could be used to predict cardiovascular risk, particularly lipid levels, systolic blood pressure (SBP) and blood glucose. Our hypothesis was that fat mass is not an accurate predictor of these cardiovascular risk factors. METHODS: 182 police officers (166 males, 16 females; age 37.6±8.1 yrs; ht 1.7±0.1 m; wt 92.2±17.8 kg; BMI 28.9±4.8) were part of an annual cardiovascular risk profile testing group. We measured resting heart rate …

Associations Of Objectively Measured Light-Intensity Activity On Metabolic Risk Factors In Female Adults, Matthew O. Mccullough, Megan E. Mcclendon, Thomas L. Andre, Michelle R. Umstattd, Cindy Wu, Shana M. Walsh, Rodney G. Bowden

International Journal of Exercise Science: Conference Proceedings

Metabolic syndrome (MetSy) has been defined as a collection of metabolic irregularities that increase the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality. Women are at an even greater risk for developing MetSy when compared to men with prevalence increasing with age. Moderate to vigorous physical activity (MVPA) has shown consistent association with decreases in risk of MetSy; however, light physical activity (LPA) has been studied less often in comparison. PURPOSE: The purpose of this study was to examine relationships between accelerometer-determined LPA and MetSy risk factors (waist circumference (WC), glucose, high density lipoprotein (HDL), triglycerides, systolic blood …

Effect Of Block Design On Swimming Relay Start Performance, Nathan D. Townsend, Shelby R. Hall, Jimmy C. Smith, Scott P. Mclean

International Journal of Exercise Science: Conference Proceedings

Starting blocks used in competitive swimming often incorporate a wedge for the rear foot to push against when performing flat starts. In most competitions, this wedge cannot be removed so relay starts must be performed with the wedge in place despite the common addition of an approach step during a relay starts. The presence of the wedge constrains the length of the approach step but does provide an inclined surface from which to push which may improve propulsive force development. PURPOSE: The purpose of this study was to evaluate the effect of using a wedge in relay start performance. METHODS: …

Dietary Enrichment Of Fish-Oils Attenuates Diet-Induced Obesity And Hepatic Steatosis, Dakota R. Kamm, Megan L. Schaller, Matthew P. Harris, Kenneth A. Witt, Karin E. Sandoval, Joshua S. Wooten

International Journal of Exercise Science: Conference Proceedings

Non-alcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess hepatic fat, exceeding 5% of total liver mass. NAFLD is present in one-third of Americans and up to 90% in those who are obese. NAFLD develops largely in part to consumption of a Western diet, defined as 40-60% kcal from saturated fats; however, a diet rich in fish-oils may prevent and reverse the development of steatosis. PURPOSE: To determine the effects of fish oils on the development of NAFLD. METHODS: C57BL/6 (n=91) mice were randomly assigned to four dietary groups for 32-weeks: 10% lard (LFL), 10% …

Impaired Sweating Responses To A Passive Whole-Body Heat Stress In Individuals With Multiple Sclerosis, Dustin R. Allen, Mu Huang, Iqra M. Parupia, Ariana R. Dubelko, Elliot M. Frohman, Scott L. Davis

International Journal of Exercise Science: Conference Proceedings

Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system (CNS), disrupting autonomic function. PURPOSE: The aim of this study was to test the hypothesis that individuals with MS have blunted control of thermoregulatory reflex increases in sweat rate (SR) and cutaneous vasodilation compared to controls during a passive whole-body heat stress (WBH). METHODS: Eighteen individuals with relapsing-remitting MS and 18 healthy controls (CON) participated in the study. Core temperature (T_core), skin temperature, heart rate, arterial blood pressure (10 min intervals), skin blood flow (laser-Doppler flowmetry: LDF), and SR were continuously measured during normothermic baseline …

Comparison Of Hamstring And Quadriceps Muscle Activity In Men And Women Performing A Body Weight Squat, Emma E. Albin, Jimmy C. Smith, Scott P. Mclean

International Journal of Exercise Science: Conference Proceedings

Multiple studies support the idea that women use a more quadriceps dominant activation pattern at the knee during stabilizing movements which may predispose them to a greater risk of ACL injury. A body weight squat is a common exercise used to strengthen knee musculature in attempt to minimize the risk of ACL injury. However, it is not clear whether this exercise activates the knee musculature in a manner that would not exacerbate the quadriceps dominance often observed in women. PURPOSE: To determine if women are more quadriceps dominant than men when performing a two-legged body weight squat. METHODS: Seven male …

Assessing The Qualitative Validity Of A Non-Invasive Ultrasound Technique For Estimating Muscle Glycogen Change, Jakob R. Allen

International Journal of Exercise Science: Conference Proceedings

Intramuscular glycogen is a primary fuel source for intense exercise and the use of an invasive muscle biopsy is still the gold-standard of measurement. PURPOSE: To assess the qualitative validity of a proprietary algorithm from ultrasound images (MuscleSound^®)(MS) for determination of intramuscular glycogen concentration compared to the body of literature reporting muscle glycogen depletion from exercise and subsequent recovery. METHODS: 12 healthy recreational students (n=1 female) (25.5 ± 1.2y, 74.0 ± 2.6kg, 174 ± 4.48cm) were recruited from campus for participation in this study. Subjects performed six bouts of six-minute efforts on a stationary cycle ergometer at 84% …

Effects Of Multi-Ingredient Pre-Workout Supplements On Repetitions-In-Reserve And Subjective Measures Of Energy, Fatigue, And Focus During Lower-Body Resistance Exercise, Amy Hurtado, Matthew Hamm, Jose G. Pineda, Austin Martin, Austin Cross, Victor Uribe, Ty B. Palmer, Grant Tinsley

International Journal of Exercise Science: Conference Proceedings

Approximately 50% of the U.S. population regularly consumes dietary supplements to enhance their health and well-being. One popular category of dietary supplements is called “pre-workout” supplements, which claims to increase subjective feelings of energy and exercise performance. PURPOSE: The purpose of the study was to examine whether two commercially available pre-workout supplements could beneficially modify resistance exercise-specific perceived exertion and subjective measures of energy, focus, and fatigue during an acute bout of lower-body resistance exercise. METHODS: This was a counterbalanced, double blind, placebo-controlled trial. Resistance-trained (i.e. 2+ hours per week of weight training over the past 6 months) females and …

Omega-3 Supplementation, Menstrual Cycle, And Acute Eccentric Exercise On Plasma Lipid Profiles, Mehul D. Nathubhai, Sarah Mckinley Barnard Phd, Yonghyeon Jo, Darryn Willoughby Phd, Yunsuk Koh Phd

International Journal of Exercise Science: Conference Proceedings

Omega-3 fatty acids supplementation and the menstrual cycle may independently influence plasma lipids and lipoproteins following acute exercise. PURPOSE: The current study investigated the effects of dietary fish oil supplement and acute eccentric exercise on plasma lipids and lipoproteins during two different phases of the menstrual cycle [mid-follicular (MF) vs. mid-luteal phase (ML)]. METHODS: As a double-blind, placebo-controlled design, 22 healthy young females (age= 20.86±1.39 years) volunteered. Participants were randomly assigned to either the fish oil (N=11) or the placebo (N=11) group. The fish oil group took a total of 6 capsules of fish oil per day (6g …

High Fat Diet Induced Obesity Impairs Skeletal Muscle Glycogen And Lipid Preservation After Adiponectin Incubation, Cesar Meza, Cynthia Montenegro, Catalina De La Peña, Lannie O'Keefe, Shaan Naughton, Anna Simcocks, Deanne Hryciw, Michael Mathai, Andrew Mcainch, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

High fat diets have been attributed as critical factors contributing to obesity and type 2 diabetes, characterized by increased lipid accumulation, impaired glucose uptake, and defects in glycogen storage in skeletal muscle. Adiponectin, an adipokine, has been shown to have antidiabetic effects by improving fat oxidation and glucose uptake. PURPOSE: To investigate the effects of adiponectin incubation, in high fat diet induced obese rats, on measures of skeletal muscle substrate metabolism including glycogen, glucose transporter 4 (GLUT4), lipid, and mitochondrial contents. METHODS: Male Sprague Dawley rats were fed a Western-style (21% fat by weight; 41% total energy) high …

Lower Skeletal Muscle Mitochondrial Content After A High Fat Diet Rich In Polyunsaturated Fatty Acids Compared To A High Fat Diet Rich In Monounsaturated Fatty Acids, Catalina De La Pena, Cesar Meza, Cynthia Montenegro, Anna Simcocks, Shaan Naughton, Lannie O'Keefe, Deanne Skelly, Michael Mathai, Andrew Mcainch, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

High fat diet (HFD) has been associated with weight gain, insulin resistance, and type 2 diabetes. The composition of fatty acids in various diets (monounsaturated, polyunsaturated, saturated) influence levels of blood insulin, glucose, and the onset of metabolic and cardiovascular diseases. PURPOSE: Determine the effects of high fat diets with alterations in the major dietary fatty acid content (a mixed fat western diet, a polyunsaturated fatty acid diet or a monounsaturated fatty acid diet) on skeletal muscle glycogen, lipid, glucose transporter 4 (GLUT4), and mitochondrial content. METHODS: Male Sprague Dawley rats were fed a 21% (by weight; 41% total …

Effects Of Impaired Peripheral Vision On Running, Ariana Weeks, Scott Mclean, Jimmy Smith

International Journal of Exercise Science: Conference Proceedings

The extent to which peripheral vision is used in the control of gait is not well understood. PURPOSE: To investigate the effect of impairing peripheral vision on gait characteristics and running economy. METHODS: Twelve college students (20.3±1.2yrs, 73.5±13.1kg, 177.6±13cm) able to complete a 5K in 31 min or faster were asked to participate in this study. After providing informed consent, participants ran on a treadmill at 6 mph until steady state VO2 was achieved for a minimum of two minutes. During the final minute of running, VO2, heart rate and heel contact times were recorded. This test was completed under …

Validity Of Wrist-Worn Physical Activity Monitors To Measure Heart Rate, Jacelyn C. Patton, Terri E. Shay, Martin G. Schmidt, Brook L. Massey, Alexander S. Davis, Nicolas Giovannitti, Merrill D. Funk, Robert S. Thiebaud

International Journal of Exercise Science: Conference Proceedings

Numerous physical activity monitors exist and are used to track and improve fitness levels. Due to the increasing popularity of these devices, newer products have been developed that measure heart rate (HR) at the wrist. Little is known about how accurate these devices are at measuring HR at the wrist and how they compare to each other. PURPOSE: To determine how accurately HR was measured by three different wrist-worn physical activity monitors. METHODS: Recreationally active men (n=9) and women (n=3) participated in this study. The average age and weight of participants was 22 ± 3 years and 73.9 ± 12 …

Acute Responses To High Intensity Interval Exercise And Moderate Aerobic Exercise On Anaerobically And Aerobically Trained Athletes, Stephanie M. Holloway, Matthew V. Bliss, Christopher M. Hearon

International Journal of Exercise Science: Conference Proceedings

High Intensity Interval Training (HIIT) is emerging as the popular method of training recently for its ability to deliver an exercise that still elicits almost the same health benefits, when compared to traditional methods of training. Those who are trained possess higher lactate thresholds than those who are not trained. However, there is little research on males whom are trained as anaerobically or aerobically, and their differences on lactate or blood glucose recovery. PURPOSE: The purpose of this study is to compare the acute effects of high intensity interval exercise and moderate aerobic exercise on lactic acid and blood glucose …

The Acute Effects Of A Dynamic Whole Body Vibration Warm-Up Combined With Blood Flow Restriction On Muscle Peak Torque, Vertical Jump Power, Heart Rate (Hr), And Blood Pressure (Bp), Maria F. De La Rosa Miss, Juanita Deese, Briana Hoysick, Alondra Chapa

International Journal of Exercise Science: Conference Proceedings

Warm-ups are crucial for minimizing risks, such as injuries, and increasing performance. Performing warm-ups on a Whole Body Vibration (WBV) platform have shown to improve performance and strength by recruiting reflex triggered contractions. PURPOSE: The purpose of this study was to observe the effects of dynamic whole body vibration with blood flow restriction on muscle peak torque (strength) and vertical jump power. METHODS: Eight females (Mean ± STDEV age = 21.8 ± 4.3 years; height = 159.7 ± 4.6 cm; Weight = 58.0 ± 16.0 kg) and eight males (Mean ± STDEV age = 21.8 ± 2.9 years; height = …

Plasma Glucose And Lipid Profiles Following High-Fat Diet And Acute Aerobic Exercise, Benjamin Son, Yonghyeon Jo, Ashton Waddell, Eric O'Neal, Yunsuk Koh

International Journal of Exercise Science: Conference Proceedings

PURPOSE: To examine the effects of a 3-week high-fat (HF) diet on plasma glucose, lipids, and lipoproteins following an acute bout of aerobic exercise in middle-aged men. METHODS: Physically active (non-elite, competitive marathon runners), male participants (N=8, age=39.5±9.9 years) volunteered for the study. Participants maintained their habitual high-carbohydrate (HC) diet (60-70% caloric intake from carbohydrate) prior to switching to the HF diet (70% caloric intake from fat, not exceeding 50g of carbohydrates) for 3 weeks. At the end of each diet trial, participants performed an acute bout of aerobic exercise, which consisted of running at varying paces (personal …

Improvement In Heart Rate Variability During Mild Cognitive Task Following Concussion, Madison S. Ferraro, Mu Huang, Justin Michael Frantz, Tonia Sabo, Kathleen Bell, Sushmita Purkayastha

International Journal of Exercise Science: Conference Proceedings

Cognitive rest is widely recommended following concussion until symptoms resolve. Unlike return-to-play protocols, there is a lack of clear guideline for return-to-learn in student athletes. Heart rate variability (HRV) is an index of cardiac health and reduced HRV is associated with disturbances in the autonomic nervous system (ANS) following concussion. PURPOSE: Therefore, the purpose of our study was to examine ANS modulation utilizing HRV at rest and during mild cognitive task in concussed and non-injured control athletes. METHODS: Nineteen collegiate athletes (20 ± 1 years) with a physician-diagnosed sports-related concussion were enrolled in the study acutely (4 ± …

Age-Associated Changes In Training Volume And Athletic Performance: Cross-Sectional And Longitudinal Analyses Of Masters Swimmers, Stephanie Lapierre, Brett Baker, Hirofumi Tanaka

International Journal of Exercise Science: Conference Proceedings

Masters athletes make every effort to maintain or even improve the athletic performance they accomplished when they were young. However, a decline in athletic performance is one of the inevitable consequences of aging. Precise physiological mechanisms of age-related decrease in athletic performance are not known but it is thought to be driven by decreases in exercise training stimuli. PURPOSE: We determined the influence of changes in training volume with aging on swimming performance by using both cross-sectional and longitudinal approaches. METHODS: Competitive swimmers who were members of the US Masters Swimming association were included if they had logged their yearly …

Cerebral Vasoreactivity Is Impaired Beyond Symptom Resolution Following Concussion In Collegiate Athletes, Justin Michael Frantz, Madison Ferraro, Tonia Sabo, Peter F. Davis, Kathleen Bell, Sushmita Purkayastha

International Journal of Exercise Science: Conference Proceedings

Compromised cerebral blood flow (CBF) regulation is linked to impaired functional outcome following concussion. Cerebral vasoreactivity (CVR), an important mechanism in CBF regulation, is the ability of cerebral blood vessels to alter blood flow during dynamic changes in arterial carbon-dioxide (CO₂). PURPOSE: The purpose of this study was to examine CVR in an ongoing prospective cohort of collegiate athletes during acute (day-3) and sub-acute (day-21) phases following concussion and compare them with non-injured athletes. METHODS: Sixteen male and female collegiate athletes (21±1 years) with sports-related concussion and 16 sports matched non-injured controls (21±1 years) were enrolled in …

High Fat Diet Rich In Saturated Fatty Acids, But Not Monounsaturated Fatty Acids, Impairs Glycogen Preservation After Adiponectin Treatment, Cynthia Montenegro, Catalina De La Pena, Cesar Meza, Shaan Naughton, Anna Simcocks, Lannie O'Keefe, Deanne Skelly, Michael Mathai, Andrew Mcainch, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

High fat diet (HFD) is associated with the progression of obesity, type 2 diabetes and diminished insulin sensitivity, which is characterized by a lower glucose uptake and glycogen synthesis capacity in skeletal muscle. Adiponectin (Ad), on the other hand, is a cytokine secreted by adipose tissue that promotes glucose uptake and fatty acid oxidation in skeletal muscle. PURPOSE: To determine the effects of Ad on skeletal muscle glycogen, GLUT 4, mitochondrial and lipid content in animals fed with a HFD but with alterations in dietary fatty acids (mixed fat western diet and predominately monounsaturated fatty acid). METHODS: Male Sprague Dawley …

The Validity Of A Novel Staged Exercise Test For Measuring Lactate Metabolism And Performance In Cyclists, Jacob B. Harp, Joe Gillespie, Max Sanderford, Jennifer Blevins-Mcnaughton

International Journal of Exercise Science: Conference Proceedings

Several types of lactate threshold (T_lac) protocols have been developed over the years to maximize accuracy and reliability while maintaining ease of measurement and application to training and performance. PURPOSE: The purpose of this study was to determine the validity of a novel staged maximal lactate steady state exercise test (sMLSS) in predicting the MLSS using the Lactate Plus® (Nova Biomedical, Waltham, MA) analyzer. METHODS: Blood lactate concentration (BLC) was measured in duplicate for all tests. Seven trained cyclists (20 miles per week) performed a V̇O_2max test starting at 100W and increasing by 30W every …

The Evaluation Of Repetitive Overhead Movements In Heating Ventilation And Air Conditioning Technicians, Joshua T. Kuehne, Sakiko Oyama

International Journal of Exercise Science: Conference Proceedings

Air conditioning technicians are the most non-fatally injured amongst construction workers. It has been identified that the shoulder is one of joints most commonly affected areas in industrial workers. While repetitive overhead movements have been evaluated in construction workers, it has not been described in air conditioning (AC) technicians. PURPOSE: To describe repetitive arm movement performed by AC technicians using inertial measurement unit (IMU) system, throughout a full work day. METHODS: An IMU is a small portable motion detection monitor that combines information from triaxial accelerometers, gyroscopes, and magnetometers to track translational movements. Six AC technicians participated on six …

Differences In Neuromuscular Adaptations After Two Weeks Of Conventional Vs Blood Flow Restriction Resistance Training, Danny D. Dominguez, Patrick G. Murphy, Brittany N. Esparza, Gabriela Soto, Roberto Osornio, Ulku Karabulut, Murat Karabulut

International Journal of Exercise Science: Conference Proceedings

PURPOSE: The purpose of the study was to determine the neuromuscular changes in the rectus femoris (RF) muscle as measured by electromyography (EMG) following short-term resistance training with and without blood flow restriction (BFR). METHODS: 12 males (age = 27.4 ± 6.3 years; height = 171 ± 7 cm; weight = 79.8 ± 13.2 kg) performed six sessions of lower body unilateral resistance training using a leg extension machine. The leg on which BFR was applied was determined through randomization leg dominance Each training session consisted of unilateral knee extensions with and without blood flow restriction. Electromyography data …

The Effects Of Short-Term Resistance Training With & Without Blood Flow Restriction On Neuromuscular Adaptations, Gabriela A. Soto, Roberto Osornio Iv, Ashley Taylor, Delisha Horne, Pedro Vasquez, Danny Dominguez, Hugo Santana, Murat Karabulut

International Journal of Exercise Science: Conference Proceedings

ABSTRACT

Initial changes in muscle strength following resistance training are proven to be due to neuromuscular adaptations in muscle fibers. For Health Fitness Specialists, there will always be a need to discover new methods for improving neuromuscular adaptations in potential clients. Resistance training with blood flow restriction is a relatively new method of training that promotes neuromuscular adaptation. PURPOSE: To investigate the neuromuscular adaptations in quadriceps muscles after short-term resistance training with and without blood flow restriction (BFR). METHODS: Twelve males (age = 27.4 ± 6.3 years; height = 171 ± 7 cm; weight = 79.8 ± 13.2 …

Effects Of Dietary Fish-Oil Supplement And Acute Eccentric Exercise On Inflammatory Markers During Different Phases Of Menstrual Cycle, Yonghyeon Jo, Sarah Mckinley Barnard, Darryn Willoughby, Yunsuk Koh

International Journal of Exercise Science: Conference Proceedings

Fish-oil supplementation may play a positive role in inflammation. Matrix Metalloproteinases (MMPs) are important in controlling tumor growth, metastasis, angiogenesis, and inflammation. Several tissue inhibitors of MMPs (TIMPs) are known to regulate the activity of specific MMPs. PURPOSE: To examine the effects of dietary fish-oil supplementation and acute eccentric exercise on MMP-1, -2, -9, and -10 and TIMP-1, -2, -3, and -4 during two different phases of menstrual cycle. METHODS: As a randomized, double-blind, and placebo-controlled design, 22 college-aged women (age= 20.86 ± 1.39 years) were randomly assigned to either a fish oil (FOG, N=11) or a placebo …

Response Time And Puzzle Solving Skills In Gamers Vs. Non- Gamers, Ashlea R. Rosenbaum, Daniel Joseph Burt

International Journal of Exercise Science: Conference Proceedings

Video gaming requires rapid response times, problem solving skills, adaptive learning and attention to detail by continuously engaging cognitive and physical reactions to cues provided via visual stimuli. Gaming more than nine hours a week has been said to positively affect individuals’ reaction times and problem solving skills. Given the advancements of technology and video gaming, an increase in research on the effects gaming has on motor and cognitive skills has yet to come. PURPOSE: To compare the response times and problem solving skills between gamers and non-gamers. METHODS : Subject (N=68) were required to complete a survey, the …

Omega-3-Fatty Acids Hold Therapeutic Potential For The Prevention And Treatment Of Diabetic Neuropathy, J. Claire Maciejewski, Matthew P. Harris, Megan L. Schaller, David S. Umbaugh, Karin E. Sandoval, Kenneth A. Witt, Joshua S. Wooten, Brianne L. Guilford

International Journal of Exercise Science: Conference Proceedings

Diabetic neuropathy is a debilitating complication of diabetes, affecting over 50% of diabetic patients. Overweight humans display manifestations of diabetic neuropathy before developing overt diabetes and mice fed a high fat diet exhibit signs of neuropathy including mechanical hindpaw hypersensitivity and neuronal inflammation, suggesting fat diet-induced inflammation may play a role in the development of neuropathy. Omega-3 (n-3) fatty acids have anti-inflammatory properties and may hold therapeutic potential as a preventative treatment for prediabetic and diabetic patients at risk for neuropathy. PURPOSE: Investigate the impact of diet composition on signs of neuropathy. We hypothesized that a diet rich in n-3 …

Relationship Between Matrix Metalloproteinases And Tissue Inhibitor Of Metalloproteinases Following High-Fat Diet And Acute Exercise, Rayomand Katrak, Yonghyeon Jo, Eric O'Neal, Yunsuk Koh

International Journal of Exercise Science: Conference Proceedings

Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix of the tissue and inflammation. Several tissue inhibitors of MMPs (TIMPs) are known to inhibit the activity of MMPs. PURPOSE: The current study investigated the responses of MMP-1, -2, -9, and -10 and TIMP-1, -2, -3, and -4 after a 3-week high-fat, low-carbohydrate (HFLC) diet following an acute aerobic exercise. METHODS: Physically active (unprofessional, competitive marathon runners) male subjects (N=8, age= 39.5 ± 9.9 years) volunteered for the study. Subjects maintained their habitual high carbohydrate (HC) diets before switching to the HFLC diet (70% total caloric …