Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (5388)
- Social and Behavioral Sciences (2000)
- Life Sciences (1170)
- Education (907)
- Dentistry (838)
-
- Psychology (776)
- Physical Sciences and Mathematics (751)
- Arts and Humanities (701)
- Medical Specialties (517)
- Medical Sciences (473)
- Sociology (452)
- Pharmacy and Pharmaceutical Sciences (334)
- Engineering (325)
- Higher Education (324)
- Public Health (316)
- Race and Ethnicity (296)
- Public Affairs, Public Policy and Public Administration (239)
- Art and Design (218)
- Nursing (197)
- Diseases (190)
- Clinical Psychology (183)
- Geriatrics (175)
- Social Work (171)
- Psychiatry and Psychology (168)
- Medical Pharmacology (155)
- Urban Studies and Planning (153)
- Educational Leadership (151)
- Biomedical Engineering and Bioengineering (149)
- Epidemiology (148)
- Biochemistry, Biophysics, and Structural Biology (147)
- Keyword
-
- Dentistry (419)
- Virginia Commonwealth University (290)
- Bulletin (193)
- Catalog (193)
- Medicine (142)
-
- Epidemiology (115)
- Geriatrics (92)
- Depression (87)
- Commencement Program (81)
- Case Study (76)
- Mental health (74)
- Cancer (71)
- Education (71)
- Contents (67)
- Anxiety (66)
- Obesity (59)
- Book review (57)
- Other (56)
- Community (55)
- Race (55)
- Virginia (55)
- Inflammation (54)
- Alcohol (53)
- Psychology (51)
- Community engagement (50)
- Richmond (49)
- Gender (46)
- Women (44)
- Trauma (43)
- Neuroscience (42)
- Publication Year
- Publication
-
- Theses and Dissertations (4473)
- Commonwealth Times, 1969- (1804)
- MCV/Q, Medical College of Virginia Quarterly (828)
- Biology and Medicine Through Mathematics Conference (430)
- VCU Board of Visitors Minutes (424)
-
- Proscript, 1940-1969 (312)
- Virginia Dental Journal (276)
- UROP Posters (261)
- VCU Today, 1972-1988 (258)
- The Medicovan, 1948-1973 (228)
- VCU Bulletins (210)
- VCU Voice, 1988-1998 (190)
- The Scarab, 1952-2010 (189)
- Sanger Historical Files (1859-1865), Excerpts (141)
- Internal Medicine Publications (131)
- Bulletin of the Virginia State Dental Association (126)
- Explorations in Ethnic Studies (119)
- Graduate Research Posters (111)
- Case Studies from Age in Action (103)
- Health Sciences Education Symposium (97)
- Journal of Social Theory in Art Education (96)
- GEHLI - 2026 VCUL Team Project Publications (92)
- Master of Urban and Regional Planning Capstone Projects (90)
- VCU Commencement Programs (81)
- The X-Ray (MCV, 1913-2010) (79)
- The Atlas, 1929-1939 (77)
- VCU Magazine, 1971-1993 (77)
- Explorations in Sights and Sounds (72)
- Psychiatry Publications (71)
- Microbiology and Immunology Publications (69)
- Publication Type
- File Type
Articles 7321 - 7350 of 14290
Full-Text Articles in Entire DC Network
Characterization And Development Of A Stroke-Induced Model Of Acquired Epilepsy In Organotypic Hippocampal Slice Cultures: Role Of The Cannabinoid Cb1 Receptors In Modulation Of Neuronal Excitation And Inhibition, Julie Ziobro
Theses and Dissertations
Stroke is the most common cause of acquired epilepsy in persons 35 and older. The massive increase in extracellular glutamate during stroke causes a cascade of intracellular events that can lead to cell death or the molecular changes that initiate the development of epilepsy. In addition, many studies point to a modulatory role of the endocannabinoid system in controlling seizures. Animal models of stroke induced acquired epilepsy have been difficult to develop. Therefore, this dissertation was initiated to develop an organotypic hippocampal slice culture model of acquired epilepsy and examine the changes in distribution and function of the endogenous CB1 …
Commonwealth Times 2010-10-28 [Front Page Has 2010-11-28]
Commonwealth Times 2010-10-28 [Front Page Has 2010-11-28]
Commonwealth Times, 1969-
No abstract provided.
The Impact Of Hurricane Katrina On The Nurse Anesthesia Community In New Orleans, Marjorie Geisz-Everson
The Impact Of Hurricane Katrina On The Nurse Anesthesia Community In New Orleans, Marjorie Geisz-Everson
Theses and Dissertations
Hurricane Katrina devastated New Orleans in 2005. Certified Registered Nurse Anesthetists (CRNAs) and Student Registered Nurse Anesthetists (SRNAs) were impacted by the storm. CRNAs were required to be on duty during the storm and SRNAs’ education was disrupted by the storm. This dissertation is a compilation of three papers that represent the initial exploratory research into the impact of natural disasters on CRNAs and future CRNAs. The first article was a focused ethnography utilizing focus groups and described the shared experiences of CRNAs who were on duty in New Orleans during Hurricane Katrina and the psychosocial impact the storm had …
Determination Of Structure Of Hepatitis B Virus E Antigen, Asheel Patel
Determination Of Structure Of Hepatitis B Virus E Antigen, Asheel Patel
Theses and Dissertations
Hepatitis B virus is a member of the hepadnavirus family. The hepatitis B virus core gene codes for two proteins viz. core protein and pre-core protein. These proteins assemble to form particles viz. HBcAg and HBeAg respectively. The structure of the HBcAg has been widely studied but very little is known about the structure of HBeAg. Therefore, the aim of this study was to identify the disulfide bonding patterns in HBeAg. Recombinant HBeAg was isolated from E.coli and used for this study along with various mutants of HBeAg. There are four cysteines present in HBeAg each at position -7, 48, …
Adenovirus-5 Infection Affects Lipid Metabolism In Hepatic And Adipose Tissues, Marianna Sukholutsky
Adenovirus-5 Infection Affects Lipid Metabolism In Hepatic And Adipose Tissues, Marianna Sukholutsky
Theses and Dissertations
Our recent studies have shown a link between Adenovirus-5 (Ad-5) and elevated lipids, which prompted the hypothesis that Ad-5 infection might augment hepatic and/or adipose tissue lipid metabolism. To test our hypothesis, mice were infected with Ad-5 and screened for changes in lipogenesis and plasma markers associated with the metabolic syndrome. We observed increased expression of sterol regulatory element binding protein 1 (SREBP-1) in infected liver tissues, but not in adipose tissues and this correlated with elevated plasma and hepatic triglyceride levels. Elevated expression of adiponectin was seen in Ad-5 infected adipose tissues and this correlated with phosphorylated AMPK in …
High-Pressure And High-Temperature Density Measurements Of N-Pentane, N-Octane, 2,2,4-Trimethylpentane, Cyclooctane, N-Decane, And Toluene, Yue Wu
Theses and Dissertations
Information on the density of hydrocarbons at high pressures and temperatures is of great importance in many fields, such as the study of ultra-deep reservoirs up to ~240 MPa and 250°C. However, density data at such high pressures and temperatures are often not available in the literature. In this study, experimental densities are reported for n-pentane, n-octane, 2,2,4-trimethylpentane, cyclooctane, n-decane, and toluene to ~280 MPa and ~250°C. These experimental densities are in good agreement with available literature data, although the literature data for many of these fluids do not extend to the pressures and temperatures utilized in this study.
Brachytherapy Seed And Applicator Localization Via Iterative Forward Projection Matching Algorithm Using Digital X-Ray Projections, Damodar Pokhrel
Brachytherapy Seed And Applicator Localization Via Iterative Forward Projection Matching Algorithm Using Digital X-Ray Projections, Damodar Pokhrel
Theses and Dissertations
Interstitial and intracavitary brachytherapy plays an essential role in management of several malignancies. However, the achievable accuracy of brachytherapy treatment for prostate and cervical cancer is limited due to the lack of intraoperative planning and adaptive replanning. A major problem in implementing TRUS-based intraoperative planning is an inability of TRUS to accurately localize individual seed poses (positions and orientations) relative to the prostate volume during or after the implantation. For the locally advanced cervical cancer patient, manual drawing of the source positions on orthogonal films can not localize the full 3D intracavitary brachytherapy (ICB) applicator geometry. A new iterative forward …
Individual Contributions To Stigma And Attitudes Toward Help-Seeking Among Rural Emerging Adult College Students, Margaret Gsell
Individual Contributions To Stigma And Attitudes Toward Help-Seeking Among Rural Emerging Adult College Students, Margaret Gsell
Theses and Dissertations
Rural communities are by definition less densely populated and more geographically isolated than non-rural communities, which often translates into higher rates of poverty and poor access to health care, especially mental health care. Previous research has found that persons residing in rural communities endorse higher rates of stigmatized beliefs towards individuals with mental illness and subsequently lower rates of professional help-seeking when compared to persons residing in non-rural communities. This study evaluated whether these attitudes were also present among emerging adults (18-24 years old) who had lived in a rural community for at least 10 years and were currently enrolled …
Mothers' Adaptation In The Neonatal Intensive Care Unit: An Examination Of The Effects Of Meaning Making, Control And Self-Enhancement On Depression, Claire Russell
Theses and Dissertations
With over 400,000 infants being hospitalized in the NICU annually, it is important to understand adjustment in their mothers. Taylor’s cognitive theory of adaptation asserts that three factors, meaning making, control, and self-enhancement, influence positive adjustment in a crisis situation such as a NICU hospitalization. Since it has never been examined, the purpose of the current study was to test the utility of Taylor’s model in mothers with an infant in the NICU. Data was collected from mothers with an infant in the NICU (N = 181) and the main hypothesis was that meaning making, control, and self-enhancement would explain …
Utilization Patterns And Economic Impact Of Iv Iron And Erythropoiesis Stimulating Agents In Chronic Kidney Disease Patients: A Multi-Hospital Study, Avani Joshi
Theses and Dissertations
Background: Chronic kidney disease (CKD) affects approximately 20 million Americans and is the cause of significant morbidity and mortality. Anemia, common in CKD, develops early in the disease process. It contributes to increased risk of cardiovascular disease, hospitalization, mortality, and diminishes health-related quality of life. Intravenous iron and Erythropoiesis Stimulating Agents (ESAs) are recommended for anemia management in CKD. The utilization patterns of IV iron and ESA, and their impact on hospital costs and length of stay merits investigation. Objectives: There were five general objectives of this investigation. The rate and extent of utilization of IV iron in anemic CKD …
The Regulation Of The Alternative Splicing Of Caspase 9, Rachel Goehe
The Regulation Of The Alternative Splicing Of Caspase 9, Rachel Goehe
Theses and Dissertations
The pro-apoptotic, caspase 9a, and the anti-apoptotic, caspase 9b, are derived from the caspase 9 gene by alternative splicing. This study demonstrates that the alternative splicing of caspase 9 is dysregulated in a large percentage of non-small cell lung cancer (NSCLC) tumors of the adenocarcinoma type. Furthermore, modulation of the levels of splice variants of caspase 9 had dramatic effects on the anchorage-independent growth and tumorigenic capacity of NSCLC cells. Due to these findings, the molecular mechanisms regulating the post-transcriptional processing of caspase 9 were therefore examined and an exonic splicing silencer (ESS) regulating the pre-mRNA processing of caspase 9 …
Antifolate Modulators Of Amp-Activated Protein Kinase Signaling As Cancer Therapeutics, Scott Rothbart
Antifolate Modulators Of Amp-Activated Protein Kinase Signaling As Cancer Therapeutics, Scott Rothbart
Theses and Dissertations
Since its discovery, it was appreciated that the antifolate pemetrexed had multiple targets within folate metabolism. This laboratory was instrumental in showing that pemetrexed elicited its primary action as a thymidylate synthase inhibitor. Unusual for an antifolate, pemetrexed showed significant clinical activity against malignant pleural mesothelioma and non-small cell lung cancer. Accordingly, the FDA recently issued first-line approvals for pemetrexed in these diseases, leading us to question whether the effects of pemetrexed on other folate-dependent targets could explain this atypical clinical activity of the drug. Studies in this dissertation showed that in addition to thymidylate synthase inhibition, pemetrexed was also …
B Cell Adam10 Activity Is Increased By Kainate Receptor Activation: Potential Role Of This Pathway In Th2 Immunity And Cancer, Jamie Sturgill
B Cell Adam10 Activity Is Increased By Kainate Receptor Activation: Potential Role Of This Pathway In Th2 Immunity And Cancer, Jamie Sturgill
Theses and Dissertations
CD23 has long been appreciated to be a natural, negative regulator of IgE synthesis. This understanding is due in part to animal models in which CD23 deficient or CD23 transgenic animals display exacerbated or reduced IgE levels respectively. Interestingly, CD23 is susceptible to proteolytic cleavage from the cell surface. When this occurs, CD23 loses its regulatory capability and the solubilized form can lead to pro-inflammatory events through its cytokinergic activity on macrophages. Thus, targeting this specific cleavage would be beneficial to the control of allergic disease by stabilizing CD23 at the cell surface. Inhibitor studies performed by our group as …
The Predictive Relationship Between Temperament, School Adjustment, And Academic Achievement: A 2-Year Longitudinal Study Of Children At-Risk, Maha Al-Hendawi
The Predictive Relationship Between Temperament, School Adjustment, And Academic Achievement: A 2-Year Longitudinal Study Of Children At-Risk, Maha Al-Hendawi
Theses and Dissertations
Individual differences in temperament can be a risk or a protective factor for a child, especially for children at-risk who possess single or multiple risk factors that may interfere with their educational success and affect their healthy development and their life-long outcomes. This research study examined the concurrent and longitudinal relationships between temperament, school adjustment, and academic achievement in children at-risk. Seventy-seven children, ages five to 11 years, were reassessed two years after an initial study. Their teachers completed the Temperament Assessment Battery for Children (TABC), the Behavior Assessment System for Children (BASC), and reported on the children's academic achievement. …
Geropsychiatric Nursing Staff: The Role Of Empowerment, Geriatric Caregiving Self-Efficacy, And Emotional Labor At Work, Ann Smolen-Hetzel
Geropsychiatric Nursing Staff: The Role Of Empowerment, Geriatric Caregiving Self-Efficacy, And Emotional Labor At Work, Ann Smolen-Hetzel
Theses and Dissertations
The current research examined the influence of the emotional labor strategies of faking emotion and suppression of emotion, empowerment, and geriatric caregiving self-efficacy on the relationship between work stress and emotional exhaustion—one dimension of burnout—for a sample of nursing staff members employed in a state-level geriatric psychiatric hospital. The total sample included 79 participants, which included registered nurses (n = 15), licensed practical nurses (n = 23) , and human service care workers (n = 41) who completed the Stress in General scale (Stanton, Balzer, Smith, Parra, & Ironson, 2001), Maslach Burnout Inventory (Human Services Survey; Maslach, Jackson & Leiter, …
Ink (2010-09)
Ink, 2008-
The student-run features magazine covering the fashion, art, music and culture worlds at VCU and in Richmond. Published annually in print and updated regularly online.
[2010-08-26] August 26, 2010 Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors
[2010-08-26] August 26, 2010 Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors
VCU Board of Visitors Minutes
Official minutes of the VCU Board of Visitors and its Executive Committee.
[2010-08-26] Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors
[2010-08-26] Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors
VCU Board of Visitors Minutes
Official minutes of the VCU Board of Visitors and its Executive Committee.
The Roads Are Bumpy Ones: A Study Of Body Image Through Abstract Performance, Alexis Goldstein
The Roads Are Bumpy Ones: A Study Of Body Image Through Abstract Performance, Alexis Goldstein
Theses and Dissertations
An overwhelming number of contemporary adolescents struggle with difficult issues. Many of these problems are socially related whereas others can be directly related to the degradation of the family unit. Among the most damaging of issues is distorted body image, which infect youth, often causing them to communicate aggressively, and even landing them in compromising situations. I have sought to challenge my students to redefine themselves through expressive movement and the creation of abstract rhythmic sounds. In teaching these techniques, I have given my former students the means to combat negative thoughts and actions, as well as an excellent tool …