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Articles 7291 - 7320 of 14290
Full-Text Articles in Entire DC Network
A Novel Method To Detect Functional Subgraphs In Biomolecular Networks, Sterling Thomas
A Novel Method To Detect Functional Subgraphs In Biomolecular Networks, Sterling Thomas
Theses and Dissertations
Several biomolecular pathways governing the control of cellular processes have been discovered over the last several years. Additionally, advances resulting from combining these pathways into networks have produced new insights into the complex behaviors observed in cell function assays. Unfortunately, identification of important subnetworks, or “motifs”, in these networks has been slower in development. This study focused on identifying important network motifs and their rate of occurrence in two different biomolecular networks. The two networks evaluated for this study represented both ends of the spectrum of interaction knowledge by comparing a well defined network (apoptosis) with and poorly studied network …
An Analysis Of Ada Title I Allegations Of Workplace Discrimination As Filed With The Eeoc By Persons With Mental Illness, Jessica E. Hurley
An Analysis Of Ada Title I Allegations Of Workplace Discrimination As Filed With The Eeoc By Persons With Mental Illness, Jessica E. Hurley
Theses and Dissertations
ABSTRACT AN ANALYSIS OF ADA TITLE I ALLEGATIONS OF WORKPLACE DISCRIMINATION AS FILED WITH THE EEOC BY PERSONS WITH MENTAL ILLNESS Jessica Erin Hurley A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Health Related Sciences—Rehabilitation Leadership Virginia Commonwealth University, 2011 Dissertation Chair: Brian T. McMahon, Ph.D., CRC This study explores employment discrimination as experienced by persons with mental illness who filed allegations under Title I (the employment provisions) of the Americans with Disabilities Act (ADA) of 1990. The entire universe of employment discrimination allegations filed under Title I of the ADA …
Depth And Time Related Variations Of Microbial Communiites In An Emergent Freshwater Wetland, Amy Jenkins
Depth And Time Related Variations Of Microbial Communiites In An Emergent Freshwater Wetland, Amy Jenkins
Theses and Dissertations
Soils, and the microbial communities contained within them, are vital for most chemical, physical, and biological processes. This study investigated how microbial community structure responded to environmental changes, such as hydrology, across vertical space (depth) and time in an emergent fresh water wetland. Research was conducted in a non-tidal freshwater wetland along the James River (Charles City County, Virginia) by establishing plots in two areas that experienced different hydrologic regimes and plant communities. Soil cores (30 cm) were collected monthly from January 2008 to February 2009, and then every two to three months thereafter until October 2009, for a total …
Approaches To Identify Surface Proteins Of Anaplasma Phagocytophilum Dense-Cored Organisms As Adhesins To Human P-Selectin Glycoprotein Ligand-1, Matthew Troese
Approaches To Identify Surface Proteins Of Anaplasma Phagocytophilum Dense-Cored Organisms As Adhesins To Human P-Selectin Glycoprotein Ligand-1, Matthew Troese
Theses and Dissertations
Anaplasma phagocytophilum is an obligatory intracellular bacterium that infects neutrophils to cause human granulocytic anaplasmosis. Sialyl Lewis x (sLex)-modified P-selectin glycoprotein ligand-1 (PSGL-1) is the confirmed receptor utilized by A. phagocytophilum to bind and invade human neutrophils and myeloid cell lines. As an obligate intracellular pathogen, the binding of A. phagocytophilum to a host cell receptor is a prerequisite step for entry and replication, and thus its survival. However, the bacterial adhesins mediating this process have yet to be identified. In this study, we sought to identify surface proteins of A. phagocytophilum as putative adhesins. A. phagocytophilum undergoes a biphasic …
Phytoremediation Of Copper Contaminated Waste Water Using Lemna Minor, Mark Apelt
Phytoremediation Of Copper Contaminated Waste Water Using Lemna Minor, Mark Apelt
Theses and Dissertations
The use of natural remediation methods to remove contaminants from waste water is becoming more popular. Plants have been used for several decades, yet their use for municipal waste water contaminated by heavy metals is limited to a few studies which focus on the Mercury and Chromium (Bennicelli, et.al, 2004). This study specifically attempted to determine the viability for using Lemna minor to remediate municipally generated wastewater contaminated with copper. The study used 100 ml samples of wastewater, artificially spiked with 8 mg/L of copper sulfate and seeded with approximately 100 Lemna minor fronds. Each treatment was repeated 15 times …
Inhibition Of Cytomegalovirus Genome Maturation By The Halogenated Benzimidazoles, Anne Sauer
Inhibition Of Cytomegalovirus Genome Maturation By The Halogenated Benzimidazoles, Anne Sauer
Theses and Dissertations
Current FDA approved anti-cytomegalovirus antivirals are ganciclovir, foscarnet, and cidofovir. These drugs target the viral polymerase to inhibit DNA synthesis. Halogenated benzimidazoles target a step later in viral replication during packaging and cleavage of the viral genome. The compounds 2-Bromo-5,6-dichloro-1-(β-D-ribofuranosyl)benzimidazole (BDCRB) and 2,5,6-trichloro-1-(β-D-ribofuranosyl)benzimidazole (TCRB) are novel inhibitors of human cytomegalovirus (HCMV) and resistance to these compounds are found within the human cytomegalovirus viral terminase. Terminase is unique to the virus and in theory provides a good target for antiviral development. Beginning with a BDCRB resistant guinea pig cytomegalovirus observations found a single mutation located in the viral terminase gene UL89 …
Eight Years Of Ubiquitous Technology Access And Digital Curricula: Business And Marketing High School Teachers’ Perspective, Eckert Mary
Theses and Dissertations
This research was conducted during the 2009-2010 school term as a case study of a large school division’s technology initiative after eight years to chronicle its effect on high school business and marketing teachers’ use and integration of technology. The 18 teachers were business and marketing teachers from eight high schools, two technical centers and one alternative school who participated in the one-to-one laptop initiative from its inception and who were asked to participate in the study. A web-based survey on technology use and adoption was administered to 18 high school business and marketing teachers. The researcher conducted a total …
Perceptions Of Teachers Regarding The Importance And Existence Of Researched-Based Program Characteristics In Alternative High Schools And Teacher’S Perceptions Of Efficacy In The Commonwealth Of Virginia, Robert Lowerre
Theses and Dissertations
The purpose of this research was to determine teachers’ perceptions of the degree to which research-based characteristics exist in alternative high schools and programs in the Commonwealth of Virginia and the importance of these characteristics to effective education. In addition, this research investigated whether or not these perceptions were related to the teachers’ perception of efficacy. These seven characteristics were (a) clearly identified enrollment criteria, (b) low ratio of student to teachers, (c) one-to-one interactions between staff and students, (d) social skills instruction, (e) effective academic instruction, (f) parental involvement and parental support programs, and (g) specific training for teachers …
Intrinsic Features Of The Multisensory Cortical Area Lrss In The Ferret, Alexandru Ioan Cojanu
Intrinsic Features Of The Multisensory Cortical Area Lrss In The Ferret, Alexandru Ioan Cojanu
Theses and Dissertations
Environmental events simultaneously transduced by more than one sensory modality underlie multisensory processing in the CNS. While most studies of multisensory processing examine functional effects, none have evaluated the influence of local or columnar circuitry. The goal of the present study is to examine of local features of the ferret lateral rostral suprasylvian sulcus (LRSS), a multisensory cortex. Immunostaining revealed the cytoarchitectonic features of the LRSS: thick supragranular layers, a narrow layer IV, and moderately stained but differentiated infragranular layers. Golgi-Cox techniques were used with light microscopy and digital reconstruction to document neuronal morphology. Among the 90 reconstructed neurons, 4 …
The Decision Making Process Of Informal Caregivers Of Dementia Family Members Regarding Nursing Home Placement, Rebecca Merritt
The Decision Making Process Of Informal Caregivers Of Dementia Family Members Regarding Nursing Home Placement, Rebecca Merritt
Theses and Dissertations
The purpose of this study was to understand the decision making process of caregivers placing their elderly family members in a nursing home facility. Experiential Learning Theory (ELT) was used, as well as the Critical Incident Technique (CIT). ELT was utilized in an effort to understand the learning that took place during the caregiving experiences, and CIT was used to better understand the critical incidents that led the caregivers to seek nursing home placement. A sample of twelve former informal dementia caregivers between the ages of fifty-seven and eighty-seven was drawn from the metropolitan Richmond, Virginia area. In-depth interviews were …
Compensation And Organizational Outcomes: Examining The Relationship Between Teacher Salaries And Student Achievement For School Divisions In Virginia, Matthew Steele
Theses and Dissertations
This research presents the results of general linear modeling (GLM) of 131 school divisions in Virginia. The purpose of this research is to answer the question: What is the relationship between teacher salaries and student achievement as measured by Adequate Yearly Progress (AYP)? Utilizing an equity theory and distributive justice perspective, data related to achievement in English and mathematics by high school students, as measured by the requirements of AYP, were culled from the Virginia Department of Education for every school division in Virginia in the subjects of reading, writing, algebra I, geometry, and algebra II. These data represent the …
The Stockbridge-Munsee Tote At The National Museum Of The American Indian, Corinne Mcveigh
The Stockbridge-Munsee Tote At The National Museum Of The American Indian, Corinne Mcveigh
Theses and Dissertations
This thesis constructs the cultural biography of the National Museum of the American Indian’s Stockbridge-Munsee tote, a twentieth-century souvenir craft, in order to examine the tote’s cultural and cross-cultural associated meanings and how these associated meanings shift from one context to another. It follows the tote’s history including its production, purchase, and transfer. This thesis briefly recounts the Stockbridge-Munsee Indians’ history and focuses on a few examples of craft objects produced prior to the 1960s, when the Stockbridge-Munsee tote was made. Wisconsin Indian Craft, a craft cooperative formed in the 1960s, produced objects such as the Stockbridge-Munsee tote. This tote, …
Ernst Ludwig Kirchner (1880-1938): Early Female Nudes In Landscapes, Kathryn Rogge
Ernst Ludwig Kirchner (1880-1938): Early Female Nudes In Landscapes, Kathryn Rogge
Theses and Dissertations
This thesis examines how Ernst Ludwig Kirchner reconceived the female nude within the two contexts of Expressionism and the German nudist movement. In particular, it looks to Kirchner’s early paintings, executed between 1909 and 1914, of female nudes in landscape settings to determine how Kirchner operated within and departed from the conventions of the female nude. This thesis challenges the feminist critique of Expressionist painting and Kirchner’s female nudes. It also examines how Kirchner’s female nudes in landscapes are complicated by the early twentieth-century development of German nudism. While these paintings are often categorized as bathers following nineteenth-century French precedent, …
[2010-11-11] Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors
[2010-11-11] Meeting Of The Board Of Visitors Of Virginia Commonwealth University, Virginia Commonwealth University. Board Of Visitors
VCU Board of Visitors Minutes
Official minutes of the VCU Board of Visitors and its Executive Committee.
Ethnic Identity Development Among Rural Adolescent Youth, Adam Iglesias
Ethnic Identity Development Among Rural Adolescent Youth, Adam Iglesias
Theses and Dissertations
The current study evaluated the factor analytic structure and developmental trajectory of ethnic identity, as measured by the Multigroup Ethnic Identity Measure, (MEIM) among early rural adolescents. The convergent validity of the measure for rural youth was also examined. The sample for this study was drawn from a larger longitudinal study focusing on violence prevention efforts with an early adolescent sample residing in rural Florida. The final sample size for these secondary analyses was 5,695 participants. The sample was 53 % Caucasian, 24% Latino, 15% African American, and 8% Other. The mean age of the students was 11.3 years. Data …
[2010-11-10] Meeting Of The Academic And Health Affairs Policy Committee, Virginia Commonwealth University. Board Of Visitors
[2010-11-10] Meeting Of The Academic And Health Affairs Policy Committee, Virginia Commonwealth University. Board Of Visitors
VCU Board of Visitors Minutes
Official minutes of the VCU Board of Visitors and its Executive Committee.
[2010-11-10] Meeting Of The External Relations Committee, Virginia Commonwealth University. Board Of Visitors
[2010-11-10] Meeting Of The External Relations Committee, Virginia Commonwealth University. Board Of Visitors
VCU Board of Visitors Minutes
Official minutes of the VCU Board of Visitors and its Executive Committee.
[2010-11-10] Meeting Of The Finance, Investment And Property Committee, Virginia Commonwealth University. Board Of Visitors
[2010-11-10] Meeting Of The Finance, Investment And Property Committee, Virginia Commonwealth University. Board Of Visitors
VCU Board of Visitors Minutes
Official minutes of the VCU Board of Visitors and its Executive Committee.
Utilization Of Simulation To Teach Pelvic Examination Skills To Medical Students: Implications For Medical Education, Brenda Seago
Utilization Of Simulation To Teach Pelvic Examination Skills To Medical Students: Implications For Medical Education, Brenda Seago
Theses and Dissertations
Medical education is changing. Physicians have less time for teaching clinical skills and for direct observation of medical students, due to sicker patients in the hospital, shorter hospital stays, competing demands of research and patient care, and implementation of the eighty hour work week for residents. The consumer movement increased awareness of medical errors, patient safety and quality of healthcare. Teaching the pelvic examination is ethically complex. Questions have arisen about medical students learning to conduct the pelvic examination on actual patients. This study utilizes the pelvic examination simulator and genital teaching associates (GTAs) to teach pelvic exam skills to …
The Impact Of Deployment And Psychological Well-Being On Family Relationships: A Secondary Analysis Of Air Force Community Assessment Data, Keita Franklin
The Impact Of Deployment And Psychological Well-Being On Family Relationships: A Secondary Analysis Of Air Force Community Assessment Data, Keita Franklin
Theses and Dissertations
Airmen serving in the U.S. Air Force have made significant contributions to the overall war efforts in Afghanistan and Iraq. Deployment, combat exposure, and subsequent combat-related mental health issues can have effects that extended beyond the airmen to the family. The primary aim of this study was to determine the path through which such effects occur within the context of risk and protective factors. The risk factors identified in this study were: deployment length and frequency and psychological symptomology. The construct of social support was also examined as an identified protective factor. This study examined the relationships between all of …
Making Authenticity: Polk Miller And The Evolution Of American Popular Culture, Jacques Vest
Making Authenticity: Polk Miller And The Evolution Of American Popular Culture, Jacques Vest
Theses and Dissertations
This thesis examines the life and musical career of James "Polk" Miller of Richmond Virginia, a Confederate veteran, and successful pharmacist. Miller claimed to offer the only authentic version of antebellum slave music, and was renowned as a convincing "negro delineator." In his focus on race, performance, and authenticity, Miller straddled a number of cultural currents linking him to his nineteenth century predecessors as well as the cultural milieu of the twentieth century. About the turn of the century, he added a black quartet to his act in order to more fully capture his conception of the "authentic" slave music …
Power And Sample Size For Three-Level Cluster Designs, Tina Cunningham
Power And Sample Size For Three-Level Cluster Designs, Tina Cunningham
Theses and Dissertations
Over the past few decades, Cluster Randomized Trials (CRT) have become a design of choice in many research areas. One of the most critical issues in planning a CRT is to ensure that the study design is sensitive enough to capture the intervention effect. The assessment of power and sample size in such studies is often faced with many challenges due to several methodological difficulties. While studies on power and sample size for cluster designs with one and two levels are abundant, the evaluation of required sample size for three-level designs has been generally overlooked. First, the nesting effect introduces …
Do General, Community Hospitals Compete By Specializing In High Volume, High Revenue-Generating Service Lines?, Nancy J. Muller
Do General, Community Hospitals Compete By Specializing In High Volume, High Revenue-Generating Service Lines?, Nancy J. Muller
Theses and Dissertations
To determine if general, community hospitals show evidence of specializing in the nation's six highest volume, highest revenue-generating service lines, 2003-2007 data of hospitals throughout Florida, Virginia, and Nevada were analyzed using backward deletion, stepwise regression. Service lines selected for study were cardiac surgery, cardiology, invasive cardiology, orthopedics, labor and delivery, and pulmonary services. Results do show evidence of specialization, but characteristics of hospitals vary by service line. Findings suggest that the general, community hospital, traditionally a full-service provider, may be undergoing transformation including specialization. The study demonstrates the usefulness of studying specialization at the service line level.
Ink (2010-11)
Ink, 2008-
The student-run features magazine covering the fashion, art, music and culture worlds at VCU and in Richmond. Published annually in print and updated regularly online.