Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (3291)
- Food Science (769)
- Nutrition (650)
- Agriculture (545)
- Animal Sciences (506)
-
- Plant Sciences (500)
- Social and Behavioral Sciences (399)
- Physical Sciences and Mathematics (382)
- Medicine and Health Sciences (316)
- Biology (267)
- Education (260)
- Environmental Sciences (234)
- Ecology and Evolutionary Biology (232)
- Dietetics and Clinical Nutrition (166)
- Agricultural Science (122)
- Dairy Science (118)
- Engineering (117)
- Psychology (101)
- Earth Sciences (98)
- Forest Sciences (86)
- Sociology (86)
- Food Processing (79)
- Soil Science (57)
- Human and Clinical Nutrition (56)
- Biomedical Engineering and Bioengineering (53)
- Arts and Humanities (51)
- Public Health (48)
- Civil and Environmental Engineering (46)
- Agricultural Economics (45)
- Horticulture (42)
- Keyword
-
- Utah State University (432)
- USU (349)
- Newspaper (318)
- The Utah Statesman (295)
- Statesman (292)
-
- Agenda (229)
- Utah (227)
- Utah State University Extension (212)
- Nutrition (188)
- Educational Policies Committee (179)
- Minutes (141)
- Faculty senate (137)
- Curriculum Subcommittee (135)
- USU Extension (121)
- Agriculture (108)
- Food (89)
- Garden (79)
- Horticulture (79)
- Vegetables (79)
- Utah State (78)
- General Catalog (67)
- Commencement (66)
- Graduation (62)
- Cattle (56)
- Milk (56)
- Alfalfa (54)
- Educational policies committee (53)
- Cheese (52)
- Scanning electron microscopy (52)
- Beef (49)
- Publication Year
- Publication
-
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (1606)
- All Current Publications (626)
- The Utah Statesman (321)
- Educational Policies Committee (298)
- All Archived Publications (192)
-
- Utah Science (190)
- Undergraduate Honors Capstone Projects (150)
- Biology (137)
- Food Structure (132)
- Nutrition, Dietetics, and Food Sciences Faculty Publications (129)
- University Catalogs (121)
- All Graduate Plan B and other Reports, Spring 1920 to Spring 2023 (120)
- Faculty Senate & Faculty Senate Executive Committee (114)
- All Graduate Theses and Dissertations, Fall 2023 to Present (110)
- UAES Bulletins (105)
- Wildland Resources Faculty Publications (96)
- Human–Wildlife Interactions (94)
- Student Research Symposium (77)
- Commencement Programs (67)
- Scanning Microscopy (66)
- Aspen Bibliography (55)
- Plants, Soils, and Climate Faculty Publications (47)
- Environment and Society Faculty Publications (44)
- Natural Resources and Environmental Issues (44)
- Faculty Honor Lectures (40)
- Biology Faculty Publications (39)
- Utah State Magazine (35)
- Wildlife Damage Management Conference (35)
- Annual Reports (29)
- Economic Research Institute Study Papers (29)
- Publication Type
- File Type
Articles 3841 - 3870 of 6098
Full-Text Articles in Entire DC Network
Utah State University Commencement 1998 – Main Campus, Utah State University
Utah State University Commencement 1998 – Main Campus, Utah State University
Commencement Programs
105th Commencement of Utah State University
Phylogenetic Characterization Of Endosymbionts In Psyllids (Hemiptera: Sternorrhyncha), Allen W. Spaulding
Phylogenetic Characterization Of Endosymbionts In Psyllids (Hemiptera: Sternorrhyncha), Allen W. Spaulding
Biology
Most sternorrhynchan insects harbor endosymbiotic bacteria in specialized cells (bacteriocytes) near the gut, which provide essential nutrients for hosts. In lineages investigated so far with molecular methods (aphids, mealybugs, whiteflies), endosymbionts apparently have arisen from independent infections of common host ancestors and cospeciated with their hosts. Some endosymbionts also exhibit putatively negative genetic effects from their symbiotic association. In this study, the identity of endosymbionts in one major sternorrhynchan lineage, psyllids (Psylloidea), was investigated to determine their position in eubacterial phylogeny and relationship to other sternorrhynchan endosymbionts. Small-subunit ribosomal RNA genes (16S rDNA) from bacteria in three psyllid species (families …
Expression And Iron Loading Of Recombinant Ferritin Homopolymers, Jia-Hsin Guo
Expression And Iron Loading Of Recombinant Ferritin Homopolymers, Jia-Hsin Guo
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Ferritin is an iron storage protein consisting of H and L chains to form a 24-subunit heropolymer. Ceruloplamin oxidizes Fe(II) and then loads the iron into ferritin. This research was conducted to determine which ferritin subunit is involved and whether a proposed iron-loading channel is required for iron loading by ceruloplasmin.
Recombinant rat liver H and L chain ferritin homopolymers, designated as rH-Ft and rL-Ft, respectively, were produced using insect cell-baculovirus and Escherichia coli expression systems. The expressed rH-Ft strongly suppressed the growth of the host. The rH-Ft expressed in the E. coli contained approximately 150 iron atoms/ferritin and was …
Protein Production In The Milk Of Genetically Engineered Animals, Katherine M. Bates
Protein Production In The Milk Of Genetically Engineered Animals, Katherine M. Bates
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
There are numerous proteins that have potential uses in commercial and scientific applications that are not utilized to their full potential. this is partly because it is not economically feasible to isolate some of these proteins from their natural sources or to produce them using bacterial fermentation methods. The purpose of this research was to target recombinant protein expression to the mammary glands of genetically engineered or transgenic animals. Foreign protein expression has been achieved in the mammary glands of rabbits, sheep, cows, and swine. By using a strong mammary gland promoter and signal peptide fused to the protein, it …
Predicting Transpiration Rates Of Hydroponically-Grown Plant Communities In Controlled Environments, Oscar Monje
Predicting Transpiration Rates Of Hydroponically-Grown Plant Communities In Controlled Environments, Oscar Monje
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Canopy transpiration is a major factor determining crop evapotranspiration and energy budgets. Unfortunately the development of robust models of canopy transpiration is hindered by a lack of reliable data due to the difficulties of making canopy-scale measurements. However, measurements of canopy water vapor and carbon fluxes via gas exchange techniques are possible in controlled environments. Simultaneous measurements of transpiration, photosynthesis, and canopy temperature were made in wheat and soybean communities. These data were used to calculate chamber aerodynamic and canopy stomata! conductances, and to model the response of canopy transpiration to CO2concentration and vapor pressure deficit. Canopy stomata! …
Limitations On Canada Goose Production At Fish Springs National Wildlife Refuge, Utah, Dorie S. Stolley
Limitations On Canada Goose Production At Fish Springs National Wildlife Refuge, Utah, Dorie S. Stolley
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Canada geese (Branta canadensis) recently have become management problems in some areas due to overpopulation. At Fish Springs National Wildlife Refuge (NWR), managers are concerned with the opposite situation. Despite attempts to boost production, only 18 to 34 goslings of the western Canada goose (B. c. moffitti) were produced per year, from 1989 to 1993. I studied the breeding population from March to July in 1996 and 1997. Results suggest that production is limited in 3 ways: low gosling survival, low nesting success for ground nests, and low number of breeding pairs.
Gosling survival to fledging …
Identification Of Non-Nuclear Receptors For 1,25-Dihydroxyvitamin D3 In Chick Kidney And Brain, Zhiheng Jia
Identification Of Non-Nuclear Receptors For 1,25-Dihydroxyvitamin D3 In Chick Kidney And Brain, Zhiheng Jia
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
1,25-dihydroxyvitamin D3 (1,25(OH)2D3) has been shown to mediate the rapid, non-nuclear stimulation of calcium and phosphate transport in chick intestine through binding to a receptor localized in the basal lateral membrane. By using an antibody to the N-terminus of the membrane receptor, studies were undertaken to determine whether a comparable protein exists in kidney and brain, and whether it is present in a particular subcellular fraction.
The first step was to establish fractionation protocols to separate subcellular organelles as judged by marker enzyme analyses. Differential centrifugation and Percoll gradient fractions were prepared from chick kidney …
Antioxidant Activity Of Carnosine And Phytate: Application As Meat Preservatives, Beom Jun Lee
Antioxidant Activity Of Carnosine And Phytate: Application As Meat Preservatives, Beom Jun Lee
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The antioxidant activity of carnosine and phytic acid was investigated using several model systems. Carnosine and phytic acid alone inhibited metal ion-catalyzed deoxyribose degradation. Carnosine strongly inhibited metal ion-catalyzed lipid peroxidation in liposomes and in ground beef homogenates. Phytic acid facilitated oxidation of Fe (II) to Fe (III), and it inhibited hemeprotein + H2O2-catalyzed lipid peroxidation in linoleic acid micelles.
Antioxidant and color stabilizing effects of carnosine and phytate were investigated in a beef model system. Both compounds increased the rate of pH decline in pre-rigor beef muscle and stabilized fresh meat color by inhibiting metmyoglobin …
Why Long-Term Marriages Last: A Review, Paula Gabell
Why Long-Term Marriages Last: A Review, Paula Gabell
Undergraduate Honors Capstone Projects
Marriage is a social institution experienced by most adults at least once in their life-time. Like any other type of institution marriage has its own set of norms and roles that are culturally specific to the area where it is being practiced. Marriage has existed in some form in almost every culture throughout time. There are four major types of marriages practiced in the world today. They are polygynous (one husband and many wives), polyandrous (one wife and several husbands), multilateral (several people of both sexes existing as a part of one marriage) and monogamous (two partners usually one male …
Protein-Based Diets: Fact Or Fiction?, Melanie Douglass
Protein-Based Diets: Fact Or Fiction?, Melanie Douglass
Undergraduate Honors Capstone Projects
Protein-based diets are once again popular among the those vulnerable to quick weight loss schemes. Advocates for these diets claim quick, permanent weight loss, disease prevention, improved physical performance, and even enhanced mental productivity. It is claimed that a diet high in carbohydrate contributes to hyperinsulinemia, fat storage, and "bad" eicosanoid production among other things. However, the detrimental effect of a low carbohydrate, high protein diet is rarely discussed. Subjects who follow protein-based diets are prone to a state of ketosis, which causes them to lose an unhealthy amount of nutrients and water. In general the protein-based diets are a …
Parental And Teacher Priorities For Children's Requisite Kindergarten Entry Skills, Kelly J. O'Claire-Esparza
Parental And Teacher Priorities For Children's Requisite Kindergarten Entry Skills, Kelly J. O'Claire-Esparza
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
This study examined mothers', fathers ', preschool teachers', and kindergarten teachers' opinions regarding children's requisite kindergarten entry skills. Participants were 101 preschool teachers from eight counties in northern Utah, as well as 113 kindergarten teachers and 286 parents of kindergartners from five school districts in northern Utah. Questionnaires were administered to assess opinions regarding (a) the preschool teachers' role in preparing children for kindergarten, (b) the parental role in preparing children for kindergarten, (c) priorities for requisite kindergarten entry skills, (d) the importance of specific skills emphasized in preschool, and (e) the importance of specific skills emphasized in kindergarten.
Findings …
Refeeding Syndrome, Christina H. Sperry
Refeeding Syndrome, Christina H. Sperry
Undergraduate Honors Capstone Projects
Refeeding syndrome is a syndrome of electrolyte abnormalities, which occurs in patients who are fed orally, enterally, or parenterally (1). Patients at high risk of getting refeeding syndrome include people with chronic malnutrition-underfeeding, classic kwashiorkor, classic marasmus, anorexia nervosa, chronic alcoholism, morbid obesity with massive weight loss, patients unfed in 7-10 days with evidence of stress and depletion, patients with prolonged fasting, and patients with prolonged intravenous hydration (1,2). Characteristics or complications of refeeding syndrome include congestive heart failure, hypercapnia, hyperglycemia, rebound hypoglycemia, hypophosphatemia, hypokalemia, hypomagnesemia, and hypocalcemia. Prevention is the key in refeeding syndrome and it can be done …
Vegetarianism, Kimberly A. Folkman
Vegetarianism, Kimberly A. Folkman
Undergraduate Honors Capstone Projects
Although vegetarian eating has been around throughout recorded history, in recent years, interest in this eating style has gone up dramatically. As the number of individuals adopting vegetarian dietary practices increases, healthcare professionals are called upon to provide guidance and advice. It is the position of The American Dietetic Association that appropriately planned vegetarian diets are healthful, are nutritionally adequate, and provide health benefits in the prevention and treatment of certain diseases. Both vegetarian and nonvegetarian eating patterns can be healthful-or detrimental to your health. Studies indicate that vegetarians often have lower morbidity and mortality rates from several chronic degenerative …
Plant-Availability Fractionation Of Nickel For Bioremediation, Jason Henrie
Plant-Availability Fractionation Of Nickel For Bioremediation, Jason Henrie
Undergraduate Honors Capstone Projects
The bioremediation of contaminated soils or the biomining of waste tillings has been explored through the use of hyperaccumulating plants such as S. polygaloides which is a nickel hyperaccumulator. However, it is important to discover which soils are well-suited for this type of process by determining the plant-availability of the nickel. By extracting the nickel sequentially with increasing severity it is possible to determine the chemical distribution, or fractionation, of nickel in a soil. One fraction is already suspected to be plant-available and correlates very well with the results of a previous plant-availability study. A calcareous Millville silt loam which …
Antioxidants And Alcohol In The Progression Of Acquired Immunodeficiency Syndrome, Laura Lynne Prestwich
Antioxidants And Alcohol In The Progression Of Acquired Immunodeficiency Syndrome, Laura Lynne Prestwich
Undergraduate Honors Capstone Projects
Wasting syndrome in acquired immunodeficiency syndrome (AIDS) appears to play a role in decline of immune function. Along with poor appetite, HIV infected individuals seem to have a tendency to be heavy alcohol drinkers which may be immunosuppressive and cause malnutrition. Altered macronutrient metabolism visibly contributes to wasting; however, micronutrient deficiencies also appear to play a role. Micronutrient deficiency has also been known to decrease immune function. As part of their role as antioxidants, P-carotene, vitamin C, vitamin E, and selenium may be helpful in altering cell production and response to cytokines and other secretions. This may decrease viral replication …
The Maternal Diet Can Prevent Neural Tube Defects, Shannon Michelle Gardner
The Maternal Diet Can Prevent Neural Tube Defects, Shannon Michelle Gardner
Undergraduate Honors Capstone Projects
Maternal diet and nutritional status have a direct impact on pregnancy course and outcome. Nutrition is critical to the development of the human embryo and fetus. Each year in the United States, approximately 4000 pregnancies are affected by neural tube defects (NTD). The most important finding in recent years has been the relationship between maternal folic acid status and NTDs. Other studies have found an association between zinc deficiency and an increased risk for having an NTD-affected pregnancy. Furthermore, some of the latest research has linked maternal obesity with the development of NTDs. The cumulative data from several studies have …
Targeting Minority Groups In Community Nutrition, Trisha Sisson Brimhall
Targeting Minority Groups In Community Nutrition, Trisha Sisson Brimhall
Undergraduate Honors Capstone Projects
A community nutritionist takes on the immense task of "improving the nutrition, and ... health of individuals and groups within communities" (1). These objectives are generally met by private sector sponsors such as health care facilities, work-site wellness programs and food banks. If the arena of public health is included, then the dietitian's scope is enlarged to include federally-funded agencies designed to improve public health and disease prevention (1). Skills required of these community dietitians not only include clinical knowledge and assessment skills, but marketing, education, and research competencies. The challenges of community nutrition range from counseling an individual on …
Herbs: What Is My Choice?, Brooke Dipoma Bouwhuis
Herbs: What Is My Choice?, Brooke Dipoma Bouwhuis
Undergraduate Honors Capstone Projects
Medicating oneself with herbal remedies has become and increasing popular phenomenon. It is estimated sales of herbal products were $3.2 million in 1997 (8). One third of educated, upper income Americans aged 25-49 years old are using these products each year (8). This paper is a compilation of information regarding the herbal industry. An overview of food and drug regulations as well as reviewing the 1994 Dietary Supplement Health Education Act clarify where industry is at today. A discussion regarding Germany's Commission E and their contribution to the herbal industry as well as reasons why the US is not following …
Ailing Hearts, Go Home: Ethnographic Storytelling And The Levels Of Experience, Bryan D. Tilt
Ailing Hearts, Go Home: Ethnographic Storytelling And The Levels Of Experience, Bryan D. Tilt
Undergraduate Honors Capstone Projects
I visited Primary Children's Medical Center on a fresh snow morning near the beginning of last winter. The hospital was not where it had been in my childhood, a quiet neighborhood in "the avenues" section of Salt Lake City; several years ago the hospital moved to a new location farther east on the Wasatch Mountain foothills, near the University of Utah Medical Center. The old brick building now sits sedate and empty at the top of a shaded hill. My memory of the old hospital is as a bright and oppressive place, full of the stuff of life and death. …
Syndrome X: A Review Of The Cluster Of Abnormalities, Diagnosis, And Treatment, Kathryn Lundgren Gurney
Syndrome X: A Review Of The Cluster Of Abnormalities, Diagnosis, And Treatment, Kathryn Lundgren Gurney
Undergraduate Honors Capstone Projects
Syndrome X is a cluster of abnormalities including insulin resistance, hypertension, dyslipidemia, upper-body obesity, increased levels of plasminogen activator inhibitor 1, decreased levels of tissue plasminogen activator, and hyperuricemia. The combined effect of these abnormalities greatly increases risk for Type 2 diabetes and coronary artery disease. Individuals at risk for Syndrome X are those with any of the abnormalities (not necessarily all) or with a family history of diabetes, hypertension, or early-onset coronary artery disease. Treatment of Syndrome X should be early and aggressive, starting with lifestyle changes. Exercise, proper diet, and weight loss all improve insulin resistance and thereby …
The Use Of Carnitine And Pyruvate In Weight Management, Karen Phyllis Bergs
The Use Of Carnitine And Pyruvate In Weight Management, Karen Phyllis Bergs
Undergraduate Honors Capstone Projects
Carnitine has been a naturally occurring compound since the beginning of the century, and was considered to be an essential nutrient for quite some time. Carnitine has many essential roles in the body. Carnitine transports fatty acids into the mitochondria for energy, controls ketogenesis, and modulates the acyl-CoA/free CoA ratio. Studies have postulated that exercise decreases carnitine in the body, therefore leading to a deficiency in athletes. Carnitine has also been used as a weight loss product because of its fatty acid oxidation function. Many nutritional supplement companies have marketed on these functions of carnitine, resulting in a big business. …
The Beneficial Effects Of Supplemental Vitamins C And E In Diabetic Subjects, Jessica Rupp Gibbons
The Beneficial Effects Of Supplemental Vitamins C And E In Diabetic Subjects, Jessica Rupp Gibbons
Undergraduate Honors Capstone Projects
Few reviews have been written related to the benefits of supplementing vitamin C and E in diabetic individuals. Excessive protein glycosylation is seen in persons with diabetes, and vitamin E and C have been shown to be beneficial in decreasing the glycosylation of proteins. In addition, vitamins E and Care potent antioxidants and actively reduce oxidation, triglycerides, and free fatty acid levels in diabetics. Diabetics may benefit from supplementing vitamins E and C.
Obesity: Environment Vs. Genetics, Kammi Marie Reeder Hansen
Obesity: Environment Vs. Genetics, Kammi Marie Reeder Hansen
Undergraduate Honors Capstone Projects
The prevalence of overweight and obese individuals is rising. Between 1980 and 1990 there was an 8% increase in the prevalence of obesity. Obesity is associated with many diseases such as hypertension, type 2 diabetes, heart disease and cancer. Over $39 billion dollars is spent annually on the illnesses associated with obesity. Our American culture has been blamed for the rise in obesity, yet there are obviously many people living in the American culture that are not obese. Researchers have turned to genetics to explain this phenomenon. This article will examine the many environmental factors that contribute to obesity and …
Parameter Estimation Of The Mountain Pine Beetle-Host Tree System, Zy Frederick Biesinger
Parameter Estimation Of The Mountain Pine Beetle-Host Tree System, Zy Frederick Biesinger
Undergraduate Honors Capstone Projects
The spatial redistribution of organisms in an ecosystem is often a complex process. Many ecosystems exhibit spatial complexity on a broad range of scales, driven by the physical environment and biotic interactions [1]. As different species aggregate and disperse in spatially complex ways, even an initially uniform environment will soon evolve spatial heterogeneity.
Sexual Differences In Survival And Competition In Grasshoppers, Marianne Harris
Sexual Differences In Survival And Competition In Grasshoppers, Marianne Harris
Undergraduate Honors Capstone Projects
A study was conducted to determine if the proportional survival of the sexes of the grasshopper, Melanoplus sanguinipes (Orthoptera, Acrididae), differs. By stocking cages in the field with grasshoppers with different body size, sex and density combinations, proportional survival could be estimated. This study revealed that, in the absence of predation, there was a lower proportional survival when both sexes were together at high densities as compared to when they together were at low densities, and when both sexes were separate at either density. Even though females, on average, are larger than males, this study found size to be insignificant. …
Sexual Differences In Survival And Competition In Grasshopers, Marianne Harris
Sexual Differences In Survival And Competition In Grasshopers, Marianne Harris
Undergraduate Honors Capstone Projects
A study was conducted to determine if the proportional survival of the sexes of the grasshopper, Melanoplus sanguinipes (Orthoptera, Acrididae), differs. By stocking cages in the field with grasshoppers with different body size, sex and density combinations, proportional survival could be estimated. This study revealed that, in the absence of predation, there was a lower proportional survival when both sexes were together at high densities as compared to when they together were at low densities, and when both sexes were separate at either density. Even though females, on average, are larger than males, this study found size to be insignificant. …
Therapy Videotape Presentation For Eating Disorder Clients: Development And Evaluation, Benita J. Quakenbush
Therapy Videotape Presentation For Eating Disorder Clients: Development And Evaluation, Benita J. Quakenbush
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Eating disorder clients show low motivation, poor follow-through, and inordinate premature dropout rates in treatment. Earlier studies support the use of pretherapy training to help clients understand the tasks and challenges of therapy. However, a pretherapy intervention, such as showing prospective clients a video that outlines recovery issues and themes, had not yet been developed specifically for the prevalent, recalcitrant problem of eating disorders. Thus, of particular interest to clinicians who treat eating disorders may be the development of a theoretically sound, pretherapy videotape that outlines recovery issues.
One of the purposes of this study was to review prior investigations …
Management Of Microbial Nitrate Production In Agricultural Soils, Wei Shi
Management Of Microbial Nitrate Production In Agricultural Soils, Wei Shi
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Nitrate (NO3-) is of central importance in the internal soil nitrogen (N) cycle. While animal wastes and nitrification inhibitors have been used in modern agriculture for decades, their effects on soil NO3- concentrations in relation to microbial NO3- production have not been well characterized. The objective of this research was to determine microbial NO3- production in relation to ammonium (NH4+) availability and nitrifier population activity in agricultural soils receiving animal wastes or nitrification inhibitors.
Several laboratory and field studies assessed the impacts of variously treated dairy wastes and …
The Role Of Ammonia In Reproductive Inefficiency In High-Producing Dairy Cows Fed Excess Rumen Degraded Protein, Douglas Scott Hammon
The Role Of Ammonia In Reproductive Inefficiency In High-Producing Dairy Cows Fed Excess Rumen Degraded Protein, Douglas Scott Hammon
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
The role of ammonia in reproductive inefficiency in early lactation dairy cows was studied in a series of experiments designed to determine the concentrations of ammonia in normal bovine follicular fluid (bFF), to determine the effects of ammonia on the bovine embryo during specific stages of development, and to test the hypothesis that elevated plasma urea nitrogen concentration is associated with elevated ammonia and urea nitrogen concentrations in the reproductive fluids.
In the first study, ammonia concentration in different size follicles and the effect of ammonia during in vitro maturation on embryo development were determined. Ammonia concentration in the bFF …
The Effects Of Retinoic Acids On The Angiogenic Growth Factors Produced By Solid Tumors, Lynn C. Burgess
The Effects Of Retinoic Acids On The Angiogenic Growth Factors Produced By Solid Tumors, Lynn C. Burgess
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
These studies investigated the effects of retinoic acid (RA) on angiogenesis. Three human, neoplastic cell lines were used to examine angiogenic promotion and/or inhibition. The cell lines, U-373MG glioblastoma, DU-145 prostate carcinoma, and TCCSUP bladder transitional cell carcinoma, were treated with the following: all-trans, 9-cis, or 13-cis RA, at doses from 0.0001 to 100 μM. Hypoxia was used to assist the expression of the angiogenic phenotype. Conditioned media (CM) were prepared by growing the tumor cells in the presence of RA and hypoxia for 24 hours, and then the CM was transferred to bovine, capillary endothelial …