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Utilization Of Alpha-1-Acid Glycoprotein Levels In The Serum As A Parameter For In Vivoassay Of Influenza Virus Inhibitors. Antivir Chem Chemother, R. W. Sidwell, M. H. Wong, K. W. Bailey, Dale L. Barnard, M. K. Jackson, Donald F. Smee

Animal, Dairy, and Veterinary Science Faculty Publications

Alpha-1-acid glycoprotein (AGP), an acute phase protein in serum assayed by single radial immunodiffusion using a commercially available kit, was found to significantly increase in mice infected with influenza A and B viruses. Experiments were run to determine the rate of increase of serum AGP and its relation to other influenza disease parameters, including lung consolidation, development of lung virus titres, decline in arterial oxygen saturation (SaO2), histopathological changes in the lung, and death of the animal. Maximal AGP levels occurred by day 3 in the animals, at about the same time lung virus titres reached their peak and inflammatory …

Inhibition Of Measles Virus Replication By 5'-Norcarbocyclic Nucleoside Analogs, Dale L. Barnard, V. Stowell, K. L. Seley, V. R. Hegde, R. Subha, P. Rajappan, S. W. Schneller, Donald F. Smee, R. W. Sidwell

Animal, Dairy, and Veterinary Science Faculty Publications

Despite intense efforts to increase vaccine coverage, measles virus (MV) still causes significant morbidity and mortality in the world, sometimes as the result of severe, chronic, lethal disease. In an effort to develop therapies to supplement immunization strategies, a number of 5′-nor carbocyclic adenosine analogues were evaluated for anti-MV activity in CV-1 monkey kidney cells. Of those compounds tested, those either unsubstituted at C4 or possessing a hydroxyl, azido or amino substituent at that position were the most active, with particularly significant inhibition of MV, strain Chicago-1. The EC50 values against this strain ranged from100 mg/ml in actively growing and …

Radio-Telemetry And Geographical Information Systems To Assess Urban Deer Zoonoses, Karmen M. Hollis, Christopher L. Anchor, James E. Chelsvig, Dwayne R. Etter, J. P. Dubey, Richard E. Warner, Laura L. Hungerford

Wildlife Damage Management Conference

Urban white-tailed deer (Odocoileus virginianus) populations can influence the epidemiology of many zoonotic diseases because they affect the distribution and abundance of pathogens and vectors. The risk of emerging zoonotic pathogens increases with human populations, as people have closer contact with wildlife in urban environments. We used radio-telemetry to study deer behavior and population dynamics in Chicago, IL. We monitored home-range use and habitat patterns for 43 radio-collared deer from 2 study sites, 1995-1999. Deer serology was conducted to test for various zoonotic diseases, such as babesiosis, encephalitis, and toxoplasmosis for 12 study locations. To analyze potential disease exposures for …

Comprehensive Management Of Commensal Bats, Stephen C. Frantz, Brian R. Laniewicz

Wildlife Damage Management Conference

This paper reviews the basic concepts behind a comprehensive management approach to managing commensal species, and then considers how this approach is applied to bats that live within and about the built environment. Management activities should take into consideration the whole environment in which the target species is active, including the periodic changes that occur within that environment. Comprehensive management includes a clear understanding of: the biology, behavior and ecology of the species to be managed; the environment in which that species is active (especially harborage location); and the appropriate intervention methods used to manage such species. Interventions fall under …

Ornamental And Turf Pest Control, Larry A. Sagers

All Archived Publications

No abstract provided.

Insights, Spring, 2000, Utah State University

Discovery Magazine

Bi-annual alumni newsletter for the College of Science of Utah State University in Logan.

The Efficacy Of Group Bereavement Interventions: An Integrative Review Of The Research Literature, Jim D. Sharpnack

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study involves a meta-analysis of the extant English language literature reporting studies of the effectiveness of bereavement therapeutic interventions. Twenty-six studies (20 adult studies; 6 child studies) were located and served as the database for the current meta-analytic study. Questions asked of the studies in this meta-analysis included:

1. Describe background variables of subjects seeking bereavement group interventions.
2. Describe leader variables of persons leading bereavement group interventions.
3. Describe intervention variables in bereavement group interventions.

The major finding of the meta-analysis was that children and adult experimental subjects benefitted from the grief interventions in comparison to their control counterparts. The ratio …

The Impact Of Minority Group Membership On Changes In Selected Health Outcomes Among Midlife Americans With Type 2 Diabetes, Brenda H. Ralls

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Minority ethnic groups have disproportionately high rates of diabetes prevalence and complications. This study examined the degree, nature, and mediation of ethnic differences in changes over time in four health outcomes: functional limitations, emotional symptomatology, psychosomatic symptomatology, and self-reported health status. The theoretical context incorporated tenets from the social characteristics and the minority status perspectives.

Data were drawn from two rounds (1992 and 1996) of the Health and Retirement Survey, a national plane survey of midlife Americans. The study focused on a subsample of 744 respondents who had been diagnosed with diabetes or high blood sugar by the time of …

Assessing The Risk Of Surface And Ground Water Contamination From Livestock Yards Management, Utah State University Extension

All Archived Publications

No abstract provided.

Assessing The Risk Of Surface And Ground Water Contamination From Livestock Manure Storage & Utilization, Utah State University Extension

All Archived Publications

No abstract provided.

1991-1992 & 1996 Utah Usage Of Ems Services By Children: Year Iii Research Report, Intermountain Injury Control Research Center, U.S. Department Of Commerce

All U.S. Government Documents (Utah Regional Depository)

This study examined how Utah children used emergency medical services (EMS) and related hospital care in 1991-1992. The EMS and hospital records were linked using special software (probabilistic linkage) . The principal findings of the study concerned the care of young children less than 5 years of age. They received fewer procedures prior to being transported to a hospital and required more time at the scene for assessment. Some interventions such as splinting of fractured arms prior to transport to a hospital were related to reduced hospital charges. Ambulance and hospital charges for children were estimated to by $35,000,000 not …

Abortion In Cattle, Clell Bagley

All Current Publications

Abortion is the premature expulsion of the fetus from the dam and usually occurs because the fetus has died in-utero. If death occurs at 1-2 months of gestation, it is usually termed “early embryonic death.”

Zoonosis Facts, Jill Webster

All Current Publications

Zoonosis is defined as “an infectious disease transmissible under natural conditions between vertebrate animals and human beings” (Mast 95). There are more than 150 diseases recognized under the umbrella of zoonosis. Some of the better known examples include: anthrax, bursilosis, hunta virus, bubonic plage, hemoragic fevers like ebola, rabies, and even AIDS.

Why Long-Term Marriages Last: A Review, Paula Gabell

Undergraduate Honors Capstone Projects

Marriage is a social institution experienced by most adults at least once in their life-time. Like any other type of institution marriage has its own set of norms and roles that are culturally specific to the area where it is being practiced. Marriage has existed in some form in almost every culture throughout time. There are four major types of marriages practiced in the world today. They are polygynous (one husband and many wives), polyandrous (one wife and several husbands), multilateral (several people of both sexes existing as a part of one marriage) and monogamous (two partners usually one male …

Antioxidants And Alcohol In The Progression Of Acquired Immunodeficiency Syndrome, Laura Lynne Prestwich

Undergraduate Honors Capstone Projects

Wasting syndrome in acquired immunodeficiency syndrome (AIDS) appears to play a role in decline of immune function. Along with poor appetite, HIV infected individuals seem to have a tendency to be heavy alcohol drinkers which may be immunosuppressive and cause malnutrition. Altered macronutrient metabolism visibly contributes to wasting; however, micronutrient deficiencies also appear to play a role. Micronutrient deficiency has also been known to decrease immune function. As part of their role as antioxidants, P-carotene, vitamin C, vitamin E, and selenium may be helpful in altering cell production and response to cytokines and other secretions. This may decrease viral replication …

Cat Plague - Veterinarian Caution, Clell Bagley

All Current Publications

Plague has been in the news from several areas in the much from world. The Center for Disease Control has become especially concerned about two aspects of plague (and these concerns affect veterinarians in Utah very directly); first, plague has been increasing in recent years in the western states and second, cats are being recognized more often as being associated with human plague cases.

Infectious Cattle Diseases And Vaccines, Clell Bagley

All Current Publications

Vaccines are available for 20 to 30 infectious diseases of cattle. With the various brand names and different combinations available, the choice of vaccines can become very complicated. Calves vaccinated under 6 months of age should generally be re-vaccinated again after that age to provide a longer lasting immunity.

Interaction Of The Human Serine Protease Inhibitor Alpha-1-Antitrypsin With Cryptosporidium Parvum, John Russell Forney

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The human serine protease inhibitor (serpin) alpha-1-antitrypsin (AAT) was studied for potential interaction with components of the protozoan parasite Cryptosporidium parvum. A homogenate prepared from C. parvum oocysts was incubated with purified human AAT, and complexes formed between the serpin and components of the homogenate were detected using an enzyme-linked immunosorbent assay (ELISA). Serpin:parasite infections were effectively blocked by preincubating AAT with a cognate target enzyme, porcine pancreatic elastase, prior to performing the ELISA on the homogenate. Incubation of a mixture of C. parvum oocysts and sporozoites with AAT demonstrated preferential fluorescence labeling of the sporozoite surface membrane by indirect …

Evaluation Of Methods Used In Meat Iron Analyses And Iron Content Of Raw, Cooked, And Cured Meats, Eldred Merlyn Clark

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This research project was divided into three parts. In the first part, heme, nonheme, and total iron methodologies for meats were evaluated. The accuracy, precision, and specificity of each method were determined by spike recoveries of heme and nonheme iron, and by analysis of National Institute of Science and Technology standard reference materials. The most reliable and practical methods were then used to determine the total, nonheme, and heme iron contents of various meats before and after cooking. The meats analyzed were beef, pork, lamb, chicken, and turkey. The wet-ashing technique was a novel procedure in which nitric acid was …

Quantitation Of Bovine Serum Albumin In Cow's-Milk-Based Infant Formulas And Removal Of Bovine Serum Albumin From Cow's Milk And Whey Protein Isolates, Patricia Z. Marincic

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Early introduction of cow's-milk-based infant formulas, in particular the ABBOS epitope of bovine serum albumin (BSA), has been implicated as an autoimmune trigger in the pathogenesis of insulin dependent diabetes mellitus (IDDM). A direct enzyme-linked immunosorbant assay (ELISA), using polyclonal anti-BSA antibodies, was developed to determine the BSA content of cow's milk and 15 infant formulas. Powdered high-whey (60%) formulas averaged 41 mg BSA/100 ml; 2% milk contained 52 mg BSA/100 ml; and the high-casein formulas averaged 13 mg/100 ml. BSA content of powdered polymeric formulas and cow's milk varied directly with the whey protein concentration (correlation coefficient = 0.8445, …

The Fate And Disposition Of Metolachlor And 2, 4-D Under Irrigated Corn And Turf, Ghassan R. Musharrafieh, Richard C. Peralta, Robert W. Hill, Howard M. Deer

Civil and Environmental Engineering Faculty Publications

A field lysimeter experiment was conducted during the summers of 1993 and 1994, at the River Laboratory, Utah State University, Logan, Utah. The intent was to study the fate and disposition of metolachlor and 2,4-D in a one dimensional soil system. Metolachlor was applied to corn and 2,4-D was applied to turf. The mobility, persistence, and degradation of these herbicides were investigated in the field lysimeters using four irrigation treatment levels on corn and two irrigation levels on turf. The four irrigation levels applied to corn were 0, 30, 60, and 120 percent of potential evapotranspiration. The two irrigation levels …

Cat Plague - Veterinarians Caution, Clell V. Bagley

All Archived Publications

No abstract provided.

Bovine Respiratory Disease, Clell Bagley

All Current Publications

Disease of the respiratory tract is a major problem for cattle and it continues to cause serious economic losses for producers. Bovine respiratory disease (BRD) causes increased death losses as well as medication costs, labor, and lost production. Many different infectious agents may cause similar clinical signs. Multiple agents are often involved in the development of BRD.

The Effect Of A Nutrition And Fitness Program On The Dietary Habits, Fitness Level, And Health Status Of Ute Indian Youth, Alison K. Lemon

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Lifestyle changes from traditional diet and activities to modem diets high in fat and sugar, and sedentary habits have increased inherited health risk for diabetes and obesity among Native American youth. Nutrition education and physical activity programs have been recommended to help reduce health-risk factors. This study evaluated a summer nutrition education and fitness program for effectiveness in improving the dietary habits, nutrition knowledge, fitness level, and health status of American Indian children ages 9-14 living on or near the Uintah-Ouray Reservation in Uintah and Duchesne Counties of Eastern Utah.

A 6-week nutrition and fitness program was conducted through the …

Where Language Touches The Earth: Folklore And Ecology In Tohono O'Odham Plant Emergence Narratives, Jennifer L. Hughes

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The historical and ecological relationships between the Tohono O'odham and the Sonoran desert landscape are expressed in the stories they tell. The Tohono O'odham have lived in the deserts of southwestern Arizona and northern Mexico for centuries, interacting with their environment and gaining intimate knowledge of desert botanical communities. Many of these interactions are dramatized in their traditional oral narratives. I have characterized those traditional oral narratives that illustrate and articulate Tohoro O'odham interrelationships with Sonoran desert botanical communities as "plant emergence narratives." These stories embody and express the reciprocal relationship between the Tohono O'odham and the plants they cultivate …

Biofilm Mediated Calculus Formation In The Urinary Tract, Robert J. C. Mclean, David J. Stickler, J. Curtis Nickel

Cells and Materials

Mineralization and subsequent calculus formation is a common complication of biofilm infections. In the urinary tract, these infected calculi often arise from infections by urease-producing bacteria. Ammonia, liberated by bacterial urease activity, increases urine pH, resulting in the precipitation of Ca and Mg as carbonateapatite {Ca₁₀(PO₄,CO₃)₆(OH,CO₃)₂} and struvite (NH₄MgP0₄·6H₂O). These minerals become entrapped in the organic matrix which surrounds the infecting organisms and ultimately grow into mature calculi. When the causative organisms grow on urinary catheters and stents, the resulting mineralization can …

Vertebrate Animal Pest Control, Usu Extension

All Current Publications

Vertebrate pest control deals with animals possessing a backbone. Vertebrate pests include any vertebrate, native or introduced, domestic or wild, which affects human health, well-being, or conflicts in some way with human activities. This conflict can be either real or perceived.

Expression Of Hamster Retinoic Acid Receptor Β2 And Β4 During Development And The Effect Of Retinoic Acid, Dolores Diaz

Biology

The retinoic acid receptors (RARs) constitute a group of nuclear proteins that belong to the steroid and thyroid-hormone receptor superfamily. They act as ligand-inducible transcriptional regulatory factors and provide a model for the molecular mechanism of action of retinoids (vitamin A derivatives). The objective of this study was to identify one or more isoforms of the retinoic acid receptor β (RARβ) in hamster embryos, and to study their expression during development and after retinoic acid (RA) treatment. Total RNA was extracted from a 12-day-old hamster embryo, reverse transcribed and tailed with dGTP. The resulting cDNA was subjected to anchored-polymerase chain …

Conjunctival Impression Cytology Assessment Of Vitamin A Status Of Migrant Children, Laura Nihan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Subclinical vitamin A deficiency was assessed in 65 Hispanic children attending four migrant Head Start programs in Utah. Subjects aged 2 to 6 years (median 3 years 10 months) were examined for evidence of vitamin A deficiency by conjunctival impression cytology. Biochemical indices for serum vitamin A, retinol-binding protein, zinc, and iron were performed.

Of eight children (12.5%) with subclinical vitamin A deficiency, one child had a marginal serum vitamin A of 11 μg/dl. Retinol-binding protein concentrations were significantly lower in two subjects with abnormal conjunctival impression cytology. Serum zinc, which when low can mimic signs of ocular vitamin …

Biomaterials Associated Infections: The Scale Of The Problem, David J. Stickler, Robert J. C. Mclean

Cells and Materials

The biomaterials used in the manufacture of implanted prosthetic devices profoundly impair the host's ability to opsonise and phagocytose invading microbes. As a result, while these devices generally provide effective relief from painful, crippling and life-threatening disorders, they can also induce vulnerability to infection in the recipients. The surfaces of the implants are susceptible to colonisation by microbial biofilms. The cells in the biofilm.s are further protected against opsonophagocytosis and are also resistant to antibacterials. Device associated infections thus tend to be refractile to antibiotic therapy and in many cases the device has to be removed before the infection will …