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The Effect Of Chlorhexidine Mouthwash Vs Propolis Mouthwash On The Nitrate-Reducing Activity Of Oral Bacteria And Vascular Control In Healthy Individuals, Stephanie Ellis Jul 2021

The Effect Of Chlorhexidine Mouthwash Vs Propolis Mouthwash On The Nitrate-Reducing Activity Of Oral Bacteria And Vascular Control In Healthy Individuals, Stephanie Ellis

The Plymouth Student Scientist

Nitrate and nitrite molecules are involved in the synthesis of nitric oxide (NO), a gaseous vasodilatory molecule, via the nitrate-nitrite-NO pathway. Oral bacteria are responsible for the reduction of nitrate to nitrite making them important regulators in NO production and vascular control. This paper aimed to investigate whether a laboratory-made propolis mouthwash maintained the oral nitrate reducing capacity (ONRC) of commensal bacteria compared with a chlorhexidine (CHX) mouthwash and the effects of this on vascular function in healthy individuals. Twenty-eight healthy participants visited the laboratory on two occasions where anthropometric, ONRC, blood pressure and vascular function data were collected. Between …


The Role Of Social Connectedness In Pro-Environmental Behaviours At A Trait And Situational Level, Bethany Pinnell Jul 2021

The Role Of Social Connectedness In Pro-Environmental Behaviours At A Trait And Situational Level, Bethany Pinnell

The Plymouth Student Scientist

This study investigated the effect of trait and situational social connectedness on participants pro-environmental behaviours (PEB). There were 90 participants split equally into two conditions, a socially included condition, used to create the feeling of social connection, and a socially excluded condition. Participants started by completing a social connectedness scale (SCS) to measure their feeling of trait social connectedness in everyday life. They then played the cyberball game on the computer which they were told was against two other participants, however it just virtual characters. In the Cyberball game participants were either included or excluded. After this they did a …


Acalabrutinib For Treatment Of Diffuse Large B-Cell Lymphoma: Results From A Phase Ib Study, P Strati, S De Vos, J Ruan, Kj Maddocks, Et Al Jul 2021

Acalabrutinib For Treatment Of Diffuse Large B-Cell Lymphoma: Results From A Phase Ib Study, P Strati, S De Vos, J Ruan, Kj Maddocks, Et Al

Peninsula Medical School

No abstract provided.


Exploring The Evidence For Broad-Spectrum Effectiveness Of Perampanel: A Systematic Review Of Clinical Data In Generalised Seizures, Eugen Trinka, Simona Lattanzi, Kate Carpenter, Tommaso Corradetti, Bruna Nucera, Fabrizio Rinaldi, Rohit Shankar, Francesco Brigo Jul 2021

Exploring The Evidence For Broad-Spectrum Effectiveness Of Perampanel: A Systematic Review Of Clinical Data In Generalised Seizures, Eugen Trinka, Simona Lattanzi, Kate Carpenter, Tommaso Corradetti, Bruna Nucera, Fabrizio Rinaldi, Rohit Shankar, Francesco Brigo

Peninsula Medical School

Background: The effectiveness of adjunctive perampanel has not been systematically assessed in seizure types other than its approved indications of focal seizures and primary generalised tonic–clonic seizures (PGTCS) in idiopathic generalised epilepsies (IGEs). Objective: We aimed to identify and review available evidence on outcomes with perampanel in generalised seizures and epilepsies to examine its potential as a broad-spectrum anti-seizure medication. Methods: Bibliographic databases of publications, clinical trials, and conference abstracts were searched up to August 2020 to identify studies reporting seizure or safety outcomes in patients of any age, with any type of epilepsy-associated generalised seizures treated with perampanel. Data …


Looking Through The Covid-19 Window Of Opportunity: Future Scenarios Arising From The Covid-19 Pandemic Across Five Case Study Sites, Isabell Richter, A Avillonosa, Victoria Cheung, Hong Ching Goh, Sofia Johari, Susan Kay, Carya Maharja, Th Nyguyen, Sabine Pahl, J Sugarjito, Joel Sumeldan, Qv Nguyen, Hien Thuc Vu, Wnswm Ariffin, Melanie C. Austen Jul 2021

Looking Through The Covid-19 Window Of Opportunity: Future Scenarios Arising From The Covid-19 Pandemic Across Five Case Study Sites, Isabell Richter, A Avillonosa, Victoria Cheung, Hong Ching Goh, Sofia Johari, Susan Kay, Carya Maharja, Th Nyguyen, Sabine Pahl, J Sugarjito, Joel Sumeldan, Qv Nguyen, Hien Thuc Vu, Wnswm Ariffin, Melanie C. Austen

School of Psychology

The COVID-19 pandemic has caused (and continues to cause) severe disruption in global and local economies and has forced countries, societies, and individuals to adapt quickly to the unprecedented and unpredictable situations. Despite the obvious negative consequences of the pandemic, many have called for efforts to identify transformative opportunities for sustainable development throughout this disorderly time. In the present paper, we explore such potential opportunities in the context of an interdisciplinary, international research project, which is focusing on sustainable marine management in biosphere reserves and marine parks in Southeast Asia. During a virtual workshop conducted as part of the GCRF …


Nutritional Support For Patients Recovering From Covid-19: A Consensus Process With Health And Social Care Sector And Patient Representatives, M Hickson, Ya Tronco-Hernandez, J Murphy, Ce Weekes, A Julian, G Frost Jul 2021

Nutritional Support For Patients Recovering From Covid-19: A Consensus Process With Health And Social Care Sector And Patient Representatives, M Hickson, Ya Tronco-Hernandez, J Murphy, Ce Weekes, A Julian, G Frost

School of Health Professions

No abstract provided.


Differentiation Of South African Coastal Rock Pool Ochthebius Is Associated With Major Ocean Currents (Coleoptera: Hydraenidae), David T. Bilton Jul 2021

Differentiation Of South African Coastal Rock Pool Ochthebius Is Associated With Major Ocean Currents (Coleoptera: Hydraenidae), David T. Bilton

School of Biological and Marine Sciences

A number of non-marine coastal invertebrate species have been found to constitute (semi-) cryptic species complexes in recent years. Here it is revealed that rather than a single widespread species, distributed from the Namibian border to the Cape south coast, South African coastal rock pool Ochthebius Leach, 1815 previously referred to Ochthebius capicola (Péringuey, 1892) comprise two distinct taxa. Ochthebius capicola (s. str.) is apparently restricted to the Benguela Ecoregion on the west coast, being replaced by Ochthebius mlamboi sp. nov., in south and east coast localities influenced by the Agulhas Current, including areas of the Eastern Cape province well …


Quantum Computer: Hello, Music!, Eduardo Reck Miranda Jul 2021

Quantum Computer: Hello, Music!, Eduardo Reck Miranda

School of Art, Design and Architecture

No abstract provided.


Eye Movement Desensitisation And Reprocessing Therapy For People With Intellectual Disability In The Treatment Of Emotional Trauma And Post Traumatic Stress Disorder: A Scoping Review, An Smith, R Laugharne, K Oak, R Shankar Jul 2021

Eye Movement Desensitisation And Reprocessing Therapy For People With Intellectual Disability In The Treatment Of Emotional Trauma And Post Traumatic Stress Disorder: A Scoping Review, An Smith, R Laugharne, K Oak, R Shankar

Peninsula Medical School

Introduction: Individuals with intellectual disability (ID) are at significant risk of developing emotional trauma and post-traumatic stress disorder (PTSD) due to altered neuropsychological functioning, increased chance of experiencing adverse life events, difficulty expressing emotions, diagnostic overshadowing and institutional failures. Eye Movement Desensitization and Reprocessing Therapy (EMDR) is efficacious in the general population, but research lacks evidence to suggest EMDR remains effective in ID. This paper assesses the evidence available on the use of EMDR to treat PTSD in ID and provide direction for future research. Methods: A scoping review using PRISMA guidance was conducted. PsychInfo, Embase and Medline were completed …


The Meaning Of Confidence From The Perspective Of Older People Living With Frailty: A Conceptual Void Within Intermediate Care Services, Frazer Underwood, Jos M. Latour, Bridie Kent Jul 2021

The Meaning Of Confidence From The Perspective Of Older People Living With Frailty: A Conceptual Void Within Intermediate Care Services, Frazer Underwood, Jos M. Latour, Bridie Kent

School of Nursing and Midwifery

No abstract provided.


Approved Mental Health Professionals, Best Interests Assessors And People With Lived Experience - An Exploration Of Professional Identities And Practice, A Report Prepared For Social Work England, J Hemmington, M Graham, A Marshall, A Brammer, K Stone, S Vicary Jul 2021

Approved Mental Health Professionals, Best Interests Assessors And People With Lived Experience - An Exploration Of Professional Identities And Practice, A Report Prepared For Social Work England, J Hemmington, M Graham, A Marshall, A Brammer, K Stone, S Vicary

More Faculty of Health Research

No abstract provided.


State Space Analysis Of Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen Jul 2021

State Space Analysis Of Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen

School of Engineering, Computing and Mathematics

No abstract provided.


Development Of The My Cult-Rural Toolkit, John Martin, Dominica Williamson, Klara Łucznik, John Adam Guy Jul 2021

Development Of The My Cult-Rural Toolkit, John Martin, Dominica Williamson, Klara Łucznik, John Adam Guy

Professional Services

The EU H2020 RURITAGE project takes 20 case studies, considered to be Role Models (RMs) of successful heritage-led rural regeneration from Europe, to analyze them and transfer knowledge and learning to a network of Replicators (Rs). To quantify the success of these RURITAGE interventions, a monitoring framework has been developed which includes a range of Key Performance Indicators (KPI) and a co-monitoring program. This program takes a bottom-up approach working with key stakeholders to understand their values. The My Cult-Rural Toolkit described in this paper has been designed and developed to support the co-monitoring program. The toolkit includes various methods …


Effects Of Rising Co2 On Algae In Japan, J Hall-Spencer, B Harvey, S Wada, L Porzio, S Agostini Jul 2021

Effects Of Rising Co2 On Algae In Japan, J Hall-Spencer, B Harvey, S Wada, L Porzio, S Agostini

School of Biological and Marine Sciences

No abstract provided.


Tourist Security, Terrorism Risk Management And Tourist Safety, S-J Agarwal, S Page, R Mawby Jul 2021

Tourist Security, Terrorism Risk Management And Tourist Safety, S-J Agarwal, S Page, R Mawby

Plymouth Business School

Tourists are easy targets for terrorists. Drawing on the example of the 2015 Sousse(Tunisia) shootings, and using a conceptual framework informed by tourist security, terrorism risk management including terrorism risk assessment, communication and due care, we analyse the management of the terror induced security risks, and the factors influencing this process. This is achieved through a firstin-the field tourism study that applies narrative analysis to legal discourse. We show tourist security was compromised by a lack of terrorism risk communication, poor policing, and limited integration of counter-terrorism strategies (e.g.inadequate implementation of environmental mitigation). Implications for terrorism risk assessment, management and …


Assessing The Impact Of A New Central Venous Access Device Training Program For Nurses: A Quasi-Experimental Evaluation Study, Wendy Burt, Lucy Spowart Jul 2021

Assessing The Impact Of A New Central Venous Access Device Training Program For Nurses: A Quasi-Experimental Evaluation Study, Wendy Burt, Lucy Spowart

Peninsula Medical School

No abstract provided.


Judging Me And You: Task Design Modulates Self-Prioritization, M Golubickis, Cn Macrae Jul 2021

Judging Me And You: Task Design Modulates Self-Prioritization, M Golubickis, Cn Macrae

School of Psychology

An extensive literature has revealed the benefits of self-relevance during stimulus processing. Compared to material associated with other persons (e.g., friend, mother), self-relevant information elicits faster and more accurate responses (i.e., the self-prioritization effect). Probing the boundary conditions of this effect, recent research has sought to identify whether the advantages of self-relevance can be attenuated (or even eliminated) under certain circumstances. Continuing in this tradition, here we explored the extent to which basic aspects of the task design modulate self-prioritization. The results of two experiments demonstrated just such an effect. During both simultaneous (i.e., Expt. 1) and sequential (i.e., Expt. …


How To Tie Dangerous Surgical Knots: Easily. Can We Avoid This?, E Drabble, S Spanopoulou, E Sioka, E Politaki, Et Al Jul 2021

How To Tie Dangerous Surgical Knots: Easily. Can We Avoid This?, E Drabble, S Spanopoulou, E Sioka, E Politaki, Et Al

Peninsula Medical School

Objective Secure knots are essential in all areas of surgical, medical and veterinary practice. Our hypothesis was that technique of formation of each layer of a surgical knot was important to its security. Design Equal numbers of knots were tied, by each of three groups, using three techniques, for each of four suture materials; a standard flat reef knot (FRK), knots tied under tension (TK) and knots laid without appropriate hand crossing (NHCK). Each knot technique was performed reproducibly, and tested by distraction with increasing force, till each material broke or the knot separated completely. Setting Temporary knot tying laboratory. …


Effects Of Vegetation, Sediment Supply And Sea Level Rise On The Morphodynamic Evolution Of Tidal Channels, A Sgarabotto, A D'Alpaos, S Lanzoni Jul 2021

Effects Of Vegetation, Sediment Supply And Sea Level Rise On The Morphodynamic Evolution Of Tidal Channels, A Sgarabotto, A D'Alpaos, S Lanzoni

School of Geography, Earth and Environmental Sciences

Tidal channels play a leading role in the morphodynamic evolution of tidal environments by driving the exchange of water, sediments, and nutrients within these systems. Despite their fundamental function on landscape construction, current knowledge on their plano‐altimetric evolution in response to environmental forcing is still limited. We developed a mathematical model to address the interplay of biogeomorphic processes on the plano‐altimetric equilibrium of a straight tidal channel flanked by adjacent intertidal platforms. The model couples a one‐dimensional hydrodynamic model with a bed evolution model. The former describes the flow field within the channel and the storage contribution of lateral shoals. …


Scramble: Sweep Comparison Research Application For Multiple Back-Gated Field Effect Measurements Of Graphene Field Effect Transistors, B O’Driscoll Jul 2021

Scramble: Sweep Comparison Research Application For Multiple Back-Gated Field Effect Measurements Of Graphene Field Effect Transistors, B O’Driscoll

School of Engineering, Computing and Mathematics

Graphene Field Effect Transistors (GFETs) are active electronic components which exploit the modulation of charge carriers in a graphene channel for a wide variety of applications such as electronic switching, amplification and biosensing. Herein describes a new software package SCRAMBLE, written in Python and developed with a graphical user interface, to speed up the routine processing of multiple back-gated electrical measurements from GFETs. For forward and reverse sweeps, SCRAMBLE automatically determines the Dirac points, positions of maximum transconductance and calculates the field effect mobilities for electrons and holes.


Phase 1b Study Of Tirabrutinib In Combination With Idelalisib Or Entospletinib In Previously Treated B-Cell Lymphoma., F Morschhauser, Mjs Dyer, Hs Walter, Et Al Jul 2021

Phase 1b Study Of Tirabrutinib In Combination With Idelalisib Or Entospletinib In Previously Treated B-Cell Lymphoma., F Morschhauser, Mjs Dyer, Hs Walter, Et Al

Peninsula Medical School

No abstract provided.


Approved Mental Health Professionals, Best Interests Assessors And People With Lived Experience - An Exploration Of Professional Identities And Practice, A Report Prepared For Social Work England, J Hemmington, M Graham, A Marshall, Et Al Jul 2021

Approved Mental Health Professionals, Best Interests Assessors And People With Lived Experience - An Exploration Of Professional Identities And Practice, A Report Prepared For Social Work England, J Hemmington, M Graham, A Marshall, Et Al

School of Health Professions

Social Work England was established under The Children and Social Work Act 2017. It is the specialist regulator for social workers in England. Social Work England officially took over from the Health and Care Professions Council (HCPC) in December 2019. It is a non-departmental public body, operating at arm’s length from the government. Social Work England has become the professional regulator for Approved Mental Health Professionals (AMHPs) and Best Interests Assessors (BIAs). In 2020 -21, Social Work England has been developing the regulatory framework to support AMHPs and the new specialism of Approved Mental Capacity Professional (AMCP), which will succeed …


Ethercat Implementation Of A Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen Jul 2021

Ethercat Implementation Of A Variable-Stiffness Tendon Drive With Non-Back-Drivable Worm-Gear Motor Actuation, Ian S. Howard, Martin F. Stoelen

School of Engineering, Computing and Mathematics

No abstract provided.


Structural Analysis Of The Challenges In Operating Pre-Positioned Warehouses For Humanitarian Relief Logistics, S Roh, D-W Kwak Jun 2021

Structural Analysis Of The Challenges In Operating Pre-Positioned Warehouses For Humanitarian Relief Logistics, S Roh, D-W Kwak

Plymouth Business School

Purpose : Operating pre-positioned warehouses for humanitarian relief logistics is often considered to be a high-risk strategy despite its advantages regarding the ability to respond to crises more rapidly. This study aims to analyze the critical challenges involved in operating such facilities to understand how such challenges arise, interact, and amplify. Research design, data, and methodology : An interpretive structural modelling (ISM) method integrated with empirical data collection is adopted to analyze seventeen representative challenges. These are deemed to be isolated as primary threats to the efficient management of pre-positioned warehouses, but are interpreted by examining their interconnectedness in a …


Recommender Systems And The Amplification Of Extremist Content, Joe Whittaker, Seán Looney, Alastair Reed, Fabio Votta Jun 2021

Recommender Systems And The Amplification Of Extremist Content, Joe Whittaker, Seán Looney, Alastair Reed, Fabio Votta

School of Law, Humanities and Social Sciences

No abstract provided.


A Report From The Nihr Uk Working Group On Remote Trial Delivery For The Covid-19 Pandemic And Beyond, J Masoli, S Hudson, Jt O’Brien, Jd Williamson, Ca Young, Cb Carroll Jun 2021

A Report From The Nihr Uk Working Group On Remote Trial Delivery For The Covid-19 Pandemic And Beyond, J Masoli, S Hudson, Jt O’Brien, Jd Williamson, Ca Young, Cb Carroll

Peninsula Medical School

No abstract provided.


A Clinical Study To Optimise A Sand Fly Biting Protocol For Use In A Controlled Human Infection Model Of Cutaneous Leishmaniasis (The Flybite Study), Vivak Parkash, Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Georgina Jones, Nina Martin, Elizabeth Greensted, Victoria Allgar, Shaden Kamhawi, Jesus G. Valenzuela, Alison M. Layton, Charles L. Jaffe, Petr Volf, Paul M. Kaye, Charles J.N. Lacey Jun 2021

A Clinical Study To Optimise A Sand Fly Biting Protocol For Use In A Controlled Human Infection Model Of Cutaneous Leishmaniasis (The Flybite Study), Vivak Parkash, Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Georgina Jones, Nina Martin, Elizabeth Greensted, Victoria Allgar, Shaden Kamhawi, Jesus G. Valenzuela, Alison M. Layton, Charles L. Jaffe, Petr Volf, Paul M. Kaye, Charles J.N. Lacey

Peninsula Medical School

Background: Leishmaniasis is a globally important yet neglected parasitic disease transmitted by phlebotomine sand flies. With new candidate vaccines in or near the clinic, a controlled human challenge model (CHIM) using natural sand fly challenge would provide a method for early evaluation of prophylactic efficacy. Methods: We evaluated the biting frequency and adverse effects resulting from exposure of human volunteers to bites of either Phlebotomus papatasi or P. duboscqi, two natural vectors of Leishmania major. 12 healthy participants were recruited (mean age 40.2 ± 11.8 years) with no history of significant travel to regions where L. major-transmitting sand flies are …


Self-Perceived Competence Of New Dental Graduates In Pakistan – A Multi-Institution Study, Haroon Shahid Qazi, Kamran Ali, Josephine Cockerill, Daniel Zahra Jun 2021

Self-Perceived Competence Of New Dental Graduates In Pakistan – A Multi-Institution Study, Haroon Shahid Qazi, Kamran Ali, Josephine Cockerill, Daniel Zahra

Peninsula Dental School

No abstract provided.


Evaluation Of A Neonatal Resuscitation Training Programme For Healthcare Professionals In Zanzibar, Tanzania: A Pre-Post Intervention Study, Xiang Ding, Li Wang, Mwinyi I. Msellem, Yaojia Hu, Jun Qiu, Shiying Liu, Mi Zhang, Lihui Zhu, Jos M. Latour Jun 2021

Evaluation Of A Neonatal Resuscitation Training Programme For Healthcare Professionals In Zanzibar, Tanzania: A Pre-Post Intervention Study, Xiang Ding, Li Wang, Mwinyi I. Msellem, Yaojia Hu, Jun Qiu, Shiying Liu, Mi Zhang, Lihui Zhu, Jos M. Latour

School of Nursing and Midwifery

No abstract provided.


Combining Realist Approaches And Normalization Process Theory To Understand Implementation: A Systematic Review, Sonia Michelle Dalkin, Rebecca J.L. Hardwick, Catherine A. Haighton, Tracy L. Finch Jun 2021

Combining Realist Approaches And Normalization Process Theory To Understand Implementation: A Systematic Review, Sonia Michelle Dalkin, Rebecca J.L. Hardwick, Catherine A. Haighton, Tracy L. Finch

Peninsula Medical School

Abstract Background Realist approaches and Normalization Process Theory (NPT) have both gained significant traction in implementation research over the past 10 years. The aim of this study was therefore to explore how the approaches are combined to understand problems of implementation, to determine the degree of complementarity of the two approaches and to provide practical approaches for using them together. Methods Systematic review of research studies combining Realist and NPT approaches. Realist methodology is concerned with understanding and explaining causation, that is, how and why policies, programmes and interventions achieve their effects. NPT is a theory of implementation that explains …