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Articles 3181 - 3210 of 10245
Full-Text Articles in Entire DC Network
The Contribution Of Poly(Adp-Ribose)Polymerase-1 Activity In The Nucleotide Excision Repair Pathway, Brenee S. King
The Contribution Of Poly(Adp-Ribose)Polymerase-1 Activity In The Nucleotide Excision Repair Pathway, Brenee S. King
Biomedical Sciences ETDs
Exposure to ultraviolet radiation (UVR) promotes the formation of UVR-induced, DNA helix distorting photolesions such as (6-4) pyrimidine-pyrimidone photoproducts (6-4 PPs) and cyclobutane pyrimidine dimers (CPDs). Effective repair of such lesions by the nucleotide excision repair (NER) pathway is required to prevent DNA mutations and chromosome aberrations. Poly(ADP-ribose)polymerase-1 (PARP-1) is a zinc-finger protein with well documented involvement in base excision repair (BER). PARP-1 is activated in response to DNA damage and catalyzes the formation of poly(ADP-ribose) subunits (PAR) that assist in the assembly of DNA repair complexes at sites of damage. In this dissertation, I present evidence for PARP-1 contributions …
Mindfulness-Based Stretching And Deep Breathing Exercises Normalize Serum Cortisol Levels And Reverse Symptoms Of Ptsd: A Prospective Randomized-Controlled Trial, Sang Hwan Kim
Health, Exercise, and Sports Sciences ETDs
Context: Cortisol, the human glucocorticoid, plays a key role in the pathophysiology of posttraumatic stress disorder (PTSD). It is known that individuals with chronic PTSD suffer from low basal cortisol levels. Endogenic normalization of basal cortisol concentration through exercise may have a therapeutic effect on treating PTSD symptoms, yet little is known about the association between exercise-induced endogenic increase of cortisol and PTSD symptom reduction. Objective: To identify whether mindfulness-based stretching and deep breathing exercise (MBX) increases basal cortisol levels, examine if MBX reduces PTSD symptom severity, and evaluate MBX as a complementary intervention for PTSD. Design: Prospective, randomized, controlled. …
President's Weekly Perspective, 11/5/2012, Robert G. Frank
President's Weekly Perspective, 11/5/2012, Robert G. Frank
President Frank's Administration
No abstract provided.
Gpsa Council Meeting, 10/27/2012, Graduate And Professional Student Association
Gpsa Council Meeting, 10/27/2012, Graduate And Professional Student Association
GPSA Meeting Agendas and Minutes
No abstract provided.
Wetland And Riparian Management Plan, Alcalde/Velarde Valley, Upper Rio Grande, New Mexico, Jessica C. Johnston
Wetland And Riparian Management Plan, Alcalde/Velarde Valley, Upper Rio Grande, New Mexico, Jessica C. Johnston
Water Resources Professional Project Reports
In New Mexico, riverine wetlands are generally associated with riparian areas found in the floodplains or once floodplains, of the Rio Grande and associated tributaries. Riverine wetlands are supported with water provided by over bank flow from the river, connection to the shallow groundwater, and/or acequia systems. Wetland and riparian areas are impacted by land uses, hydromodification and other activities that occur within a watershed. Wetland and riparian areas play an important role within a watershed by providing many beneficial environmental functions. This paper examines watershed issues affecting the quality of remaining wetland and riparian resources in the valley and …
President's Weekly Perspective, 10/22/2012, Robert G. Frank
President's Weekly Perspective, 10/22/2012, Robert G. Frank
President Frank's Administration
No abstract provided.
Bill To Protect Sierra Caral Remains Stalled In Congress, Louisa Reynolds
Bill To Protect Sierra Caral Remains Stalled In Congress, Louisa Reynolds
NotiCen
No abstract provided.
Full Proceedings, Vijaya R. Sharma, Mukti P. Upadhyay, Jeffrey Drope, Naresh Nepal
Full Proceedings, Vijaya R. Sharma, Mukti P. Upadhyay, Jeffrey Drope, Naresh Nepal
Himalayan Policy Research Conference
Papers, abstracts and proceedings of the Seventh Annual Himalayan Policy Research Conference, Thursday, October 11, 2012, Madison Concourse Hotel and Governors' Club, Preconference Venue of the 41st South Asian Conference at the University of Wisconsin-Madison
Determining Carbon Abatement Cost Through The Integration Of Remotely Sensed Land Cover Observations And Biogeochemical Model, Keshav Bhattarai
Determining Carbon Abatement Cost Through The Integration Of Remotely Sensed Land Cover Observations And Biogeochemical Model, Keshav Bhattarai
Himalayan Policy Research Conference
This paper estimates the economic returns of carbon abatement through biological sequestration in the forests of Nepal under future REDD policy. Using sequential remotely sensed land cover observations and a biogeochemical model, this paper attempts to estimate the contemporary and future ecosystem carbon trends. The paper applies the General Ensemble Biogeochemical Modeling System (GEMS) and examines how effective carbon sequestration can be through a sustainable forest management approach. This study uses a case example of the Bara district of Nepal for the period of 1970-2010.
Bill To Protect Sierra Caral Remains Stalled In Congress, Louisa Reynolds
Bill To Protect Sierra Caral Remains Stalled In Congress, Louisa Reynolds
NotiEn: An Analytical Digest About Energy Issues in Latin America
This article discusses the conservation efforts to protect Sierra Caral, the most biodiverse forest remnant in Guatemala, from severe deforestation. This is occurring largely due to the forced displacement of campesinos by narco-ranchers in the Motagua Valley. In addition, the article provides the bill's aspects and an in-depth look at what the Sierra Caral conservationists are proposing in their efforts to be sensitive to the displaced residents.
Papers, Abstracts, And Proceedings Of The Seventh Annual Himalayan Policy Research Conference, Vijaya R. Sharma, Mukti P. Upadhyay, Jeffry Drope, Naresh Nepal, Alok Bohara
Papers, Abstracts, And Proceedings Of The Seventh Annual Himalayan Policy Research Conference, Vijaya R. Sharma, Mukti P. Upadhyay, Jeffry Drope, Naresh Nepal, Alok Bohara
Himalayan Research Papers Archive
Papers and abstracts from the Seventh Annual Himalayan Policy Research Conference (HPRC) held at the Madison Concourse Hotel and Governor's Club in Madison, WI. The event was a pre-conference proceeding of the 41st South Asian Conference at the University of Wisconsin, Madison on October 11, 2012. Session topics included South-South Cooperation and Developmental Issues, Resources and Environment, Political and Administrative Restructuring, and Gender, Ethnic, Health and Education Issues.
President's Weekly Perspective, 10/8/2012, Robert G. Frank
President's Weekly Perspective, 10/8/2012, Robert G. Frank
President Frank's Administration
No abstract provided.
Nanoscience & Microsystems 2012 Apr Self-Study & Documents, University Of New Mexico
Nanoscience & Microsystems 2012 Apr Self-Study & Documents, University Of New Mexico
UNM Academic Program Review
UNM Nanoscience & Microsystems APR self-study and review team report for Fall 2012, fulfilling requirements of the Higher Learning Commission.
“Indians, In A Jurisdictional Sense”: Tribal Citizenship And Other Forms Of Non-Indian Consent To Tribal Criminal Jurisdiction, Paul Spruhan
“Indians, In A Jurisdictional Sense”: Tribal Citizenship And Other Forms Of Non-Indian Consent To Tribal Criminal Jurisdiction, Paul Spruhan
Faculty Scholarship
Can tribes exert criminal jurisdiction over non- Indians who consent, by whatever means, to adhere to tribal laws? Has federal Indian law, and tribes’ reaction to it, changed the universe of tribal jurisdiction so significantly that non-Indians can truly never be subject to tribal criminal law? This article explores the concept of consent as a still viable theory of tribal criminal jurisdiction. I first examine some historical examples of non-Indian consent through adoption or naturalization under tribal law, and reactions to such consent by federal officials. I then discuss modern examples of tribal law theories of consent, primarily through recent …
Gpsa Council Meeting, 9/29/2012, Graduate And Professional Student Association
Gpsa Council Meeting, 9/29/2012, Graduate And Professional Student Association
GPSA Meeting Agendas and Minutes
No abstract provided.
Faculty Senate Summarized Minutes, 9/25/2012, Unm Faculty Senate
Faculty Senate Summarized Minutes, 9/25/2012, Unm Faculty Senate
Faculty Senate Meeting Minutes, 1920 - 2013
No abstract provided.
Gpsa Legislative Steering Committee Meeting, 9/18/2012, Graduate And Professional Student Association
Gpsa Legislative Steering Committee Meeting, 9/18/2012, Graduate And Professional Student Association
GPSA Meeting Agendas and Minutes
No abstract provided.
Adobe Medicus 2012 5 September-October, Health Sciences Library And Informatics Center
Adobe Medicus 2012 5 September-October, Health Sciences Library And Informatics Center
adobe medicus
No abstract provided.
Factors Related To Successful Course Completion In An Online Program For Returning High School Dropouts, Barbara Rothweiler
Factors Related To Successful Course Completion In An Online Program For Returning High School Dropouts, Barbara Rothweiler
Organization, Information and Learning Sciences ETDs
Dropping out of high school has been declared an educational crisis in the United States with national and individual consequences. In New Mexico, adult dropouts only option for a high school credential has been a GED. In August 2010, Graduate New Mexico (GNM), an online asynchronous program, was implemented to help adult dropouts earn a high school diploma. The program was closed in March 2011. The purpose of this study is to determine the factors related to successful course completion of the GNM program that helped returning dropout students complete online course work. Using a qualitative design and interviews as …
Viscous Flow Past Plates, Xu Ling
Viscous Flow Past Plates, Xu Ling
Mathematics & Statistics ETDs
I devise a numerical method of high order in space (FDMHS) to simulate flow past a finite plate and a semi-infinite plate. The method solves the incompressible Navier-Stokes equation in the stream function-vorticity formulation. The focus is to study a fundamental problem in fluid dynamics, namely, flow past sharp edges. Resolving this flow structure is difficult, in particular at early times. The difficulty is due to the fact that large velocity gradients and vorticity are present in a very thin boundary layer attached to the plate initially. FDMHS is a splitting method, implicit in time and uses compact fourth order …
A New Class Of Neural Architectures To Model Episodic Memory : Computational Studies Of Distal Reward Learning, Shawn Taylor
A New Class Of Neural Architectures To Model Episodic Memory : Computational Studies Of Distal Reward Learning, Shawn Taylor
Electrical and Computer Engineering ETDs
A computational cognitive neuroscience model is proposed, which models episodic memory based on the mammalian brain. A computational neural architecture instantiates the proposed model and is tested on a particular task of distal reward learning. Categorical Neural Semantic Theory informs the architecture design. To experiment upon the computational brain model, embodiment and an environment in which the embodiment exists are simulated. This simulated environment realizes the Morris Water Maze task, a well established biological experimental test of distal reward learning. The embodied neural architecture is treated as a virtual rat and the environment it acts in as a virtual water …
Vers Une Ecocritique Postcoloniale Africaine: L’Environnement Dans Les Litteratures Africaines De Langue Française, Marie Chantale Mofin Noussi
Vers Une Ecocritique Postcoloniale Africaine: L’Environnement Dans Les Litteratures Africaines De Langue Française, Marie Chantale Mofin Noussi
Foreign Languages & Literatures ETDs
This work was motivated by two major facts: the African environment is at the heart of the continents relationships with colonialism, neocolonialism and globalization; but there is not enough literary emphasis on this environmental centrality. This work contributes in bridging the gap between African Francophone Literatures and the environmental discourses. This dissertation is the literary analysis of the representation, the transformation, and the exploitation of the African environment in the operating policies of colonial, neocolonial and global power structures. These environmental policies in the colonial and current global world tend to mold the African environment in a way that the …
Structure To Function: Case Studies Of Hotdog-Fold Superfamily Thioesterases From Escherichia Coli, John A. Latham
Structure To Function: Case Studies Of Hotdog-Fold Superfamily Thioesterases From Escherichia Coli, John A. Latham
Chemistry and Chemical Biology ETDs
My doctoral research primarily focuses on the Escherichia coli hotdog-fold thioesterases ydiI and ybgC. The ydiI gene is colocalized in the operon ydiHIJ. A substrate screen provided evidence that YdiI prefers aryl-CoA substrates and discriminated against the analogous aryl-ACP, unlike the paralog YbdB which works on 2,4-DHB-EntB in the enterobactin synthesis pathway. A bioinformatic approach showed that in some bacteria, ydiI is colocalized with genes from the menaquinone pathway. YdiI was shown to catalyze the hydrolysis of DHNA-CoA with physiological relevance (kcat/KM ~ 105). Furthermore, the E. coli YdiI- strain was shown to …
Alkynal Involved Organocatalytic Reactions, Xinshuai Zhang
Alkynal Involved Organocatalytic Reactions, Xinshuai Zhang
Chemistry and Chemical Biology ETDs
During the past twenty years, vast progress has been achieved in the field of organocatalysis. One of the fruitful areas is iminium catalysis using α, β-unsaturated aldehydes as essential reactants. Enals involved enantioselective reactions (including single-step reactions and cascade/tandem reactions) represent an enormous and fruitful research branch. In contrast, the protocols for the corresponding alkynals, even in single-step conjugate addition reactions, are extremely rare. Toward this end, my Ph. D. research work mainly focuses on the development of alkynal involved organocatalytic reactions and expands the scope of organocatalysis by uncovering new activation modes. Unlike enals, ynals with sp hybridized C≡C …
The Effects Of Acetate Concentrations On Competition Between Microbial Populations In Enhanced Biological Phosphorus Removal From Wastewater, Yunjie Tu
Civil Engineering ETDs
Enhanced biological phosphorus removal (EBPR) is a popular modification of the activated sludge process, and has been studied and applied for decades. It was hypothesized that the bacteria responsible for EBPR, polyphosphate accumulating organisms (PAOs), have an advantage over their competitors, the glycogen accumulating organisms (GAOs). Because research EBPR systems have been primarily sequencing batch reactors (SBRs), which include rapid feed addition and relatively high substrate concentrations, while full scale systems often include complete mix reactors, which yield generally lower substrate concentrations due to instantaneous dilution of influent, evaluating this hypothesis has both fundamental and applied implications. The primary objectives …
In Vitro Cytotoxicity And Skin Irritation Testing Of Antimicrobial Conjugated Electrolytes : Interactions With Mammalian Cells, Kristin N. Wilde
In Vitro Cytotoxicity And Skin Irritation Testing Of Antimicrobial Conjugated Electrolytes : Interactions With Mammalian Cells, Kristin N. Wilde
Chemical and Biological Engineering ETDs
An estimated 19,000 deaths and $3-4 billion in health care costs per year in the U.S. are attributed to methicillin-resistant Staphylococcus aureus (MRSA) infections. Certain cationic phenylene ethynylene (CPE)-based polymers (PPEs) and oligomers (OPEs) have been demonstrated to exhibit dark and light-activated antimicrobial activity. Envisioned applications of these CPEs include the fabrication of antimicrobial surfaces to reduce or prevent the spread of potentially untreatable strains of bacteria. Until recently, it was unknown if the polymers or oligomers would exhibit similar biocidal activity toward mammalian cells. This work examines the toxicity of CPEs to mammalian cells at three levels: cytoxicity testing …
Methods Of Cellular Integration And Techniques For Improving Encapsulated Cell Viability For The Purpose Of Developing Living Materials And Cell Based Bio-Sensing Materials, Travis J. Savage
Chemical and Biological Engineering ETDs
Living materials offer the potential for detection-reporter systems based on living cells that are genetically tailored to sense target analytes with high levels of specificity and accuracy. A biotic or living material would allow the development of simple, hand held devices that could be utilized for many applications including industrial process monitoring, environmental remediation, military and defense applications and drug delivery. Many living materials have been developed and characterized but they still lack heightened and prolonged encapsulated cell viability necessary to make the material a candidate for widespread use. One particular material offers several advantages to increase yeast cell viability …
Nutrient Dynamics In A Headwater Stream : Use Of Continuous Water Quality Sensors To Examine Seasonal, Event, And Diurnal Processes In The East Fork Jemez River, Nm, Lauren R. Sherson
Nutrient Dynamics In A Headwater Stream : Use Of Continuous Water Quality Sensors To Examine Seasonal, Event, And Diurnal Processes In The East Fork Jemez River, Nm, Lauren R. Sherson
Earth and Planetary Sciences ETDs
Stream water quality can change substantively over seasonal, event, and diurnal scales. Multiple biogeochemical processes operate on a 24-hour timescale, and also may be influenced by local weather and precipitation events. Increased sampling frequency, made possible by recent developments in continuous water quality monitors, allows us to better understand biogeochemical responses to these events. Continuous water quality sensors were deployed in the East Fork Jemez River (located in northern New Mexico) from 2010 – 2011 to investigate the temporal variability of nutrient concentrations and biogeochemical parameters and the controls on this variation. This thesis is split into two chapters representing …
The Relationship Of Multimodal Executive Function Measurement And Associated Neuroanatomical Factors In Preschoolers Born Very Low Birth Weight And Full Term, Susanne Duvall
Psychology ETDs
Objective: The current study investigated executive function (EF) in preschoolers born very low birth weight (VLBW) and full term by examining the dimensionality of EF and the relationship between multimodal measures of EF. Additionally, we investigated the neuroanatomical factors that may relate to EF in this population. Participants and methods: The sample included 101 preschoolers: 61 VLBW and 40 full term (mean=45.98 months (SD=5.05). EF measures included: Bear Dragon, Gift Touch, Gift Peek, Progressive Executive Categorization Battery, parent rated EF (BRIEF-P), and Child Compliance observational coding. Magnetic resonance imaging (MRI) data were analyzed through voxel-based morphometry (VBM) for a subset …
Keeping Faith : Factors Contributing To Spiritual Transformation, Identity, And Maturity In Church-Attending Adolescents, Glory Emmanuel
Keeping Faith : Factors Contributing To Spiritual Transformation, Identity, And Maturity In Church-Attending Adolescents, Glory Emmanuel
Psychology ETDs
The current research study investigated factors associated with spiritual development among church-attending adolescents. Eighty five participants (12 — 19 years) attending church youth groups in the Albuquerque area were asked to complete a questionnaire measuring spiritual transformation, identity, and maturity as well as demographics, personality, religious social support, and personal devotional activities. The purpose of this research was to understand how religious social support (family, friends, church, mentorship) and personal devotional activities (prayer, worship, study of sacred texts) were related to a spiritual transformation experience, spiritual identity, and spiritual maturity. It was hypothesized that adolescents who reported having had a …