Digital Commons Network^™

Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski

Biomedical Engineering Faculty Patents

A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in the fluid bath for at least 1,000 cycles. The articulation may be performed in three stages. In the first, the implant is articulated under a load of substantially 0.1-500 Newtons with sliding speeds of substantially 0.01-0.5 meters per second. During a second stage the articulation takes place under a load of substantially 200-2,500 …

College Of Law Commencement Program, 1996, University Of Kentucky

Graduation Programs

No abstract provided.

Phenylbutyl Nitrone Compositions And Methods For Prevention Of Gastric Ulceration, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient, are disclosed for treating or preventing gastric ulceration caused by ingestion of non-steroidal anti-inflammatories. Based on animal studies, the dosage is in the range of 3 to 300 mg/kg and is administered prior to, simultaneously, or shortly after ingestion of the NSAID compounds(s). In the preferred embodiment, the range is between 10 and 30 mg/kg, depending on the dosage unit required to protect the mucosa. The preferred method of administration is orally, alone or in combination with the non-steroidal anti-inflammatory. It is believed …

Plastic Heart, Black Box, Iron Cage: Instrumental Reason And The Artificial Heart Experiment, Thomas Strong

disClosure: A Journal of Social Theory

No abstract provided.

Coated-Products With Potent Anti-Hiv And Antimicrobial Properties, George Digenis, Alexander G. Digenis

Pharmaceutical Sciences Faculty Patents

A composition which has potent anti-HIV activity. The composition is a high energy coprecipitate of nonoxynol-9 oligomers, polyvinyl-pyrrolidone (PVP) and iodine or PVP-I and shows a pronounced synergistic, anti-HIV effect between the compounds of the composition. The invention also includes paper and plastic products coated with the composition of the invention.

Reproductive Freedom: Abortion Rights Of Incarcerated And Non-Incarcerated Women, Sarah Tankersley

Kentucky Law Journal

No abstract provided.

A Feminist Social Justice Approach To Reproduction-Assisting Technologies: A Case Study On The Limits Of Liberal Theory, Joan C. Callahan, Dorothy E. Roberts

Kentucky Law Journal

No abstract provided.

Evaluation Of The Crop Growth Component Of The Root Zone Water Quality Model For Corn In Ohio, Sue E. Nokes, Feliks M. Landa, Jon D. Hanson

Biosystems and Agricultural Engineering Faculty Publications

The Root Zone Water Quality Model (RZWQM) is a computer model developed to simulate water, chemical, and biological processes in the root zone of agricultural management systems. As of this writing RZWQM is in the beta-testing phase of development. This article reports on a parameterization and evaluation study performed in Ohio on field corn for the crop growth component of RZWQM. The generic crop growth model in RZWQM had not previously been parameterized or tested on field corn. This article reports the results of such a study. One year of data was used to calibrate RZWQM, and two additional years …

Monitoring The Dynamics Of Scaled Vehicles Using A Sonic Digitizer, Michael J. Bader, Larry G. Wells, Linus R. Walton

Biosystems and Agricultural Engineering Faculty Publications

Certain dynamic stability characteristics of an alternate method of mounting a front-end loader to a farm tractor were compared to those of a conventionally mounted front-end loader operating on a specified terrain. One objective of the study was to determine if the alternate method of mounting a front-end loader resulted in better stability characteristics and, in turn, safer operation than a conventional front-end loader. Another objective was to determine if a three-dimensional sonic digitizer could monitor the motion of the scale model tractor-loader systems accurately enough to perform a comparison between the systems. This article describes the second objective of …

Comparison Of Daily Water Table Depth Prediction By Four Simulation Models, Eric D. Desmond, Andrew D. Ward, Norman R. Fausey, Stephen R. Workman

Biosystems and Agricultural Engineering Faculty Publications

The Agricultural Drainage And Pesticide Transport (ADAPT) model was compared to the water management simulation models DRAINMOD, SWATREN, and PREFLO. SWATREN and PREFLO are one-dimensional finite-difference models while ADAPT and DRAINMOD are one-dimensional mass balance models. ADAPT, an extension of the computer model GLEAMS, also provides chemical transport information. All four models were tested against field data from Aurora, North Carolina. Observed water table depth data were collected during 1973 through 1977 from a water table management field experiment with three subsurface drain spacing treatments of 7.5, 15, and 30 m.

Both the standard error of estimate and the average …

Performance Of Vegetative Filter Strips With Varying Pollutant Source And Filter Strip Lengths, Puneet Srivastava, Dwayne R. Edwards, Tommy C. Daniel, Philip A. Moore Jr., Thomas A. Costello

Biosystems and Agricultural Engineering Faculty Publications

Vegetative filter strips (VFS) can reduce runoff losses of pollutants such as nitrogen (N) and phosphorus (P) from land areas treated with fertilizers. While VFS effectiveness is considered to depend on lengths of pollutant source and VFS areas, there is little experimental evidence of this dependence, particularly when the pollutant source is manure-treated pasture. This study assessed the effects of pollutant source area (fescue pasture treated with poultry litter) length and VFS (fescue pasture) length on VFS removal of nitrate N (NO₃-N), ammonia N (NH₃-N), total Kjeldahl N (TKN), ortho-P (PO₄-P), total P (TP), …

1x27 Cartoons About Science, Mark S. Coyne

Plant and Soil Sciences Faculty Book Gallery

A tongue-in-cheek look at the world of natural science.

Hydrogeology, Hydrogeochemistry, And Spoil Settlement At A Large Mine-Spoil Area In Eastern Kentucky: Star Fire Tract, David R. Wunsch, James S. Dinger, Page B. Taylor, Daniel I. Carey, C. Douglas R. Graham

Report of Investigations--KGS

An applied research program at the Star Fire surface mine in eastern Kentucky, owned and operated by Cypress-AMAX Coal Co., defined spoil characteristics to develop and monitor water resources, which will help identify a reliable water supply for future property development. Water stored in the mine spoil may provide a usable ground-water supply, and the spoil could also be engineered to provide base flow to surfacewater reservoirs.

Ground-water recharge enters the spoil by way of sinking streams, ground-water flow from bedrock in contact with the mine spoil, and a specially designed infiltration basin. Ground water discharges predominantly from springs and …

Fish Lateral Line Neurophysiological And Neurobehavioral Responses As A Sensitive Water Quality Monitoring System, Hong Y. Yan

KWRRI Research Reports

Cadmium is a heavy metal ion that can cause deleterious effects on aquatic animals. This study uses both electrophysiological recordings from lateral line nerves and videotaping of schooling behavior to investigate the effects of cadmium exposure on fish. The fathead minnows were exposed to cadmium at a concentration of 450 μg/1 over a 24-hr period. Extracellular recording with a silver hook electrode was used to record compound action potentials from the lateral lines of control and experimental fish. After a short time exposure (24 hr) to cadmium ions, all of the electrophysiological activities of the lateral line nerves were suppressed. …

So You Want To Be A Soil Microbiologist?, Mark S. Coyne

Plant and Soil Sciences Faculty Book Gallery

A tongue-in-cheek look at soil microbiology.

The Kentucky Board Of Bar Examiners' Character And Fitness Certification Questionnaire: Are Mental Health Inquiries A Violation Of The Americans With Disabilities Act?, Lanny King

Kentucky Law Journal

No abstract provided.

An Examination Of The Training And Reliability Of The Narcotics Detection Dog, Robert C. Bird

Kentucky Law Journal

No abstract provided.

A Multilateralist Method Of Choice Of Law, Scott Fruehwald

Kentucky Law Journal

No abstract provided.

The Status Of Women Under International Human Rights Law And The 1995 Un World Conference On Women, Beijing, China, Margaret Plattner

Kentucky Law Journal

No abstract provided.

"The Cornerstone Of A New Civilization": The First International Council Of Women And The Campaign For "Social Purity", Kathi L. Kern

Kentucky Law Journal

No abstract provided.

The Case For A "Strong" Regulatory Compliance Defense, Richard C. Ausness

Law Faculty Scholarly Articles

Federal administrative agencies have established safety standards or licensing procedures for airplanes, motor vehicles, pesticides, drugs, medical devices, and a variety of other products. At the same time, product sellers are subject to tort liability even though their products comply with applicable federal safety standards. Product sellers maintain that compliance with federal safety standards ought to protect them from liability under state tort law and have relied upon several legal principles to support this claim. The first, and most successful, theory is federal preemption. Under this concept, Congress may expressly or impliedly assert the primacy of federal law under the …

A Direct, Approximate Solution To The Modified Green-Ampt Infiltration Equation, Puneet Srivastava, Thomas A. Costello, Dwayne R. Edwards

Biosystems and Agricultural Engineering Faculty Publications

Accurately predicting the rainfall-runoff process is of vital importance for water quality models as well as for correct design of various types of hydraulic structures. This article presents a method of describing the cumulative infiltration process as an explicit function of time using an approximation to the modified Green-Ampt equation given by Mein and Larson (1971). The resulting equation is helpful in predicting cumulative infiltration and therefore infiltration capacity for computer simulation models. The proposed method takes about 50% less time than the usual iterative technique for the same degree of accuracy. The maximum error due to approximation was 1% …

Simulation Of Runoff Transport Of Animal Manure Constituents, Yang Wang, Dwayne R. Edwards, Tommy C. Daniel, H. Don Scott

Biosystems and Agricultural Engineering Faculty Publications

Runoff losses of land-applied animal manure constituents can adversely affect the quality of downstream waters. Reliable mathematical simulation models can help estimate runoff losses of animal manure constituents and identify management measures to reduce these losses. The objective of this study was to develop and calibrate an event-based simulation model to describe the runoff transport of solids (soil and manure particles) and nutrients (nitrogen and phosphorus) from areas treated with animal manure. The resulting model, consisting of linked hydrology, soil/manure transport, and nutrient transport components, is process-oriented and uses measurable parameters to the greatest degree possible. The three components of …

Quality Of Runoff From Four Northwest Arkansas Pasture Fields Treated With Organic And Inorganic Fertilizer, Dwayne R. Edwards, Tommy C. Daniel, John F. Murdoch, Philip A. Moore Jr.

Biosystems and Agricultural Engineering Faculty Publications

Long-term land application of animal manures, even at agronomic rates, can promote accumulation of soil phosphorus (P) which can, in turn, contribute to increased P loadings to downstream waters. The objective of this study was to assess the soil and runoff effects of replacing animal manure as a soil amendment with inorganic fertilizer (ammonium nitrate, NH₄NO₃) on fields that had been treated previously with animal manures. Runoff from two pairs of small fields (0.57 to 1.46 ha) was sampled from September 1991 to April 1994. All fields had been treated previously with animal manures; after runoff …

Poultry Litter-Treated Length Effects On Quality Of Runoff From Fescue Plots, Dwayne R. Edwards, Philip A. Moore Jr., Tommy C. Daniel, Puneet Srivastava

Biosystems and Agricultural Engineering Faculty Publications

Using experimental data and/or mathematical simulation models to identify practices that reduce pollution from manure-treated areas is sometimes perceived as limited by the unknown validity of extrapolating plot-scale data to larger areas and by uncertainties in modeling transport of various pollutants. The objectives of this study were to assess the effect of length of manure treatment on runoff concentrations of poultry litter constituents and to define the modes of transport (particulate versus soluble) for nitrogen (N), phosphorus (P), carbon (C), and solids. Poultry litter was applied to three 1.5- x 18.3-m fescue (Festuca arundinacea Schreb.) plots with runoff collection …

Application Of Simplified Phosphorus Transport Models To Pasture Fields In Northwest Arkansas, Dwayne R. Edwards, C. T. Haan, Andrew N. Sharpley, John F. Murdoch, Tommy C. Daniel, Philip A. Moore Jr.

Biosystems and Agricultural Engineering Faculty Publications

Runoff transport of phosphorus (P) is often predicted from simple equations with parameters determined from data applicable primarily to row-cropped and fallow cover conditions. The applicability, accuracy, and precision of such P transport prediction equations under pasture situations are less well defined. The objectives of this study were to determine parameters of simplified runoff P transport equations for pasture fields and to assess the accuracy and precision of the equations. Runoff, sediment yield, soluble P transport, and particulate P transport data were collected from four pasture fields in northwestern Arkansas. Runoff event enrichment ratios and extraction coefficients were computed, and …

Development Of A Biologically Based Aerobic Composting Simulation Model, Dennis P. Stombaugh, Sue E. Nokes

Biosystems and Agricultural Engineering Faculty Publications

A relatively simple dynamic model based on microbial process kinetics has been developed for aerobic composting. Differential equations describing microbial, substrate, and oxygen concentrations, as well as moisture and temperature profiles have been derived as a function of vessel size and aeration rate. Microbial biomass growth was described using Monod growth kinetics as a function of degradable substrate concentration, oxygen concentration, moisture content, and compost temperature. Facility and fan operating costs have been included to permit economic optimization of the process. Predicted results demonstrated the ability of the model to quantify and describe the influence of multiple interacting factors (temperature, …

Phenyl Butyl Nitrone Compositions And Methods For Treatment Of Oxidative Tissue Damage, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions for treating tissue damage from ischemia contain PBN, or active derivatives thereof, which are active during ischemia in preventing ATP depletion of the cells which predisposes them to subsequent injury during reperfusion, and which are active during reperfusion as oxygen radical scavengers, in a suitable pharmaceutical carrier for systemic or local administration, especially to the CNS, spinal column and eyes. Based on animal studies, the dosage for treating damage due to stroke is in the range of 10 to 300 mg/kg. Similar dosages are useful in treating damage resulting from free radical generation during inflammation, either as a product …

Polyamine-Polyamine And Polyamine-Protein Transport Inhibitor Conjugates And Their Use As Pharmaceuticals And In Research Relating To Polyamine Transport, Shewan M. Aziz, Mark N. Gillespie

Pharmaceutical Sciences Faculty Patents

Novel classes of inhibitors which selectively inhibit the cellular transport of normally transported substances, specifically polyamines are taught which comprise (i) polymers of the transported substance or (ii) protein or polypeptide conjugates of the transported substance. These inhibitors may be used in vitro to assess the effect of the transported substance on cellular functions and in vivo for treating disease conditions involving transport of the particular substance, e.g., a polyamine.

Involvement Of P59FynT In Interleukin-5 Receptor Signaling, Mark W. Appleby, James D. Kerner, Sylvia Chien, Charles R. Maliszewski, Subbarao Bondada, Roger M. Perlmutter

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Previous studies implicate the nonreceptor protein tyrosine kinase (PTK) p59fyn in the propagation of signals from the B cell antigen receptor. To elucidate the functions of this kinase, we examined B cell responsiveness in mice engineered to lack the hematopoietic isoform of p59fyn. Remarkably, antigen receptor signaling was only modestly defective in fyn^Tnull B cells. In contrast, signaling from the interleukin (IL)-5 receptor which ordinarily provides a comitogenic stimulus with antiimmunoglobulin, was completely blocked. Our results document the importance of p59fyn^T in IL-5 responses in B cells, and they support a general model …