Digital Commons Network^™

Breaking The Perpetual Social Injustice Cycle By Implementing Race-Neutral Alternatives As A Means To Create Equitable Admissions Practices In Higher Education, Jazmin B. C. Jardim-Phipps

Cardozo Journal of Equal Rights & Social Justice

The article argues that higher education institutions can still achieve the compelling state interest of diversity while complying with the Students for Fair Admissions (SFFA) rulings by replacing race-based admissions with narrowly tailored, race-neutral alternatives. It proposes a model that redefines merit and prioritizes socioeconomic and first-generation status while eliminating legacy preferences to break cycles of systemic social injustice.

The Crucial Role Of Machine Learning Models In Predicting Current Childhood Asthma: Model Comparison, Calibration, And Shap-Based Interpretation, Aditya Chakraborty, A. K.M. Raquibul Bashar

Epidemiology, Biostatistics, & Environmental Health Faculty Publications

Background: Asthma is one of the most prominent chronic diseases in children and one of the most challenging ailments to diagnose in infants and preschoolers in the United States. Predictive models can be instrumental in improving early diagnosis, personalized treatment strategies, and disease progression. By utilizing nationalized data, this study focuses on building and comparing high-performing analytical predictive models based on the relevant risk factors and identifying the most influential predictors.

Methods: We analyzed cross-sectional BRFSS Asthma Call-Back Survey data (2011-2020; N = 9,813) and randomly split participants into training and testing sets. An XGBoost model (hyperparameters tuned via grid …

Intratracheal Interleukin-10 Administration Reduces Acute Lung Injury Induced By Sulfur Dioxide Exposure In Mice, Amy J. Nelson, Todd A. Wyatt, Bradley W. Richmond, Belinda Diaz, Angela Gleason, Michael J. Duryee, Geoffrey M. Thiele, Ted R. Mikuls, Jill A. Poole

Journal Articles: Environmental, Agricultural & Occupational Health

Therapies capable of reducing acute high-consequence airborne chemical exposure-induced lung disease are lacking. This study seeks to determine the therapeutic potential of interleukin (IL)-10 administered following acute sulfur dioxide (SO₂) exposure in mice. C57BL/6 male and female mice were exposed to SO₂ gas at 125 ppm for 4 h and subsequently treated 2-3 h later with IL-10 (1 μg) or vehicle control by intratracheal instillation for a total of 3 doses over 2 days with comparisons to sham-treated mice (N = 20 mice/group). IL-10 treatment reduced SO₂-induced weight loss with corresponding reductions in SO_{2 …}

Microbiota Characterization Of Zostera Marina Seeds At Early Stage Development, Gina Chaput, Torrie Hanley, Jonathan A. Eisen, E. Maggie Sogin, A. Randall Hughes, Cynthia G. Hays

Biology Faculty Publications

Understanding seagrass seed microbiomes is crucial for developing microbial-mediated methods to improve germination in restoration efforts. Here, we used 16S rRNA gene and ITS2 amplicon sequencing to characterize the bacterial and fungal communities of seeds from the model seagrass, Zostera marina.

Teaching Students To Prompt Ai For Understanding: Evidence-Based Strategies From A Calculus Course, Jared Campbell, Joo Young Park Ph.D

Teaching & Learning with AI

No abstract provided.

Place Matters: Investigating The Social And Environmental Drivers Of Hypertension In Nashville, Marquinta Harvey, Michael D. Oliver, Tatum Brown, Deya Rassul, Thomas Strickler, Jarod Parrish, Catherine Bass

Funded Scholarship

Hypertension disparities persist across communities, driven by interactions between social determinants of health (SDOH) and behavioral factors. This study examines geographic and demographic patterns of hypertension in Nashville, Tennessee, to assess how socioeconomic, environmental, and behavioral factors contribute to inequities in prevalence, treatment, and control. Granular ZIP code-level analyses highlight community-specific drivers and the need for policy reforms to advance health equity.

Investigating The Potential Neurotoxic Effects Of Cell-Free Factors By Batrachochytrium Dendrobatidis On Locomotion In Xenopus Laevis, Anna Lennon, Laura K. Reinert, Louise A. Rollins-Smith, Will Best, Chase T. Kinsey Phd

Funded Scholarship

Chytridiomycosis is a contributor to amphibian population declines. Diseased amphibians show symptoms of lethargy and loss of righting reflexes, likely due to ion imbalance across the skin. However, it is possible developing zoosporangia release toxins that affect neuromuscular activity. Using Xenopus laevis as a model, we hypothesized that locomotor performance would be affected by injection of Bd supernatant factors. X. laevis were injected and then filmed performing a swimming escape response with high-speed cameras at 4 hours, 24 hours, and 1- week post-injection. Average maximum swimming velocity and escape latency were digitized using high speed video. Despite no difference in …

Correlates Of Recovery Capital Among Women In Jails: Leveraging A Dimensional Recovery Framework, Amanda Fallin-Bennett, Martha Tillson, Jaxin Annett, Hartley Feld, Michele Staton

Nursing Faculty Publications

Background: Recovery capital encompasses internal and external factors that support recovery from substance use disorder, such as employment, social support, and physical and mental health. There is a need for more research on recovery capital among women who are incarcerated, who often face complex barriers to recovery, such as poverty, unemployment, and histories of trauma.

Methods: Women (N ¼ 900) were recruited from Kentucky jails as part of the broader NIDA-funded Kentucky Justice Community Opioid Innovation Network (JCOIN) cooperative project. Measures from baseline interviews (during incarceration) were selected in alignment with the Substance Abuse Mental Health Service Administration (SAMHSA)’s four …

Micrornas Regulated By Pregnancy Target Antiviral And Cancer Immunity Overlapping With The Hiv Interactome, Paula F. T. Cezar-De-Mello, Jonathan M. Dreyfuss, Pai-Lien Chen, Hidemi Yamamoto, Xiaoming Gao, Hui Pan, Charles Morrison, Gustavo F. Doncel, Robert L. Barbieri, Raina N. Fichorova

CONRAD Publications

Innate immunity predictors of HIV-1 risk and pathogenesis vary with reproductive hormones, pregnancy, and lactation, yet the underlying mechanisms remain unclear. We hypothesized that pregnancy-associated physiological adaptations alter systemic microRNA (miRNA) expression, thereby regulating immunity, pathogenesis and susceptibility to infection. We analyzed 174 serum samples from 88 participants in a longitudinal cohort from Uganda and Zimbabwe across pre-pregnancy (PP), pregnancy (P), and postpartum breastfeeding (BF). Cell-free peripheral blood miRNAs (n = 2083) were profiled using HTG EdgeSeq. Pregnancy-specific miRNAs were identified by intersecting differentially expressed (DE) miRNAs from P vs. PP and P vs. BF comparisons. miRNA targets and pathways …

Comparison Of Enrichment Interaction Duration Between Male And Female Panthera Leo Leo, Maegen G. Meldrum

Undergraduate Honors Thesis Projects

African lion (Panthera leo leo) populations have declined significantly over the past century within their natural habitats, increasing the importance of effective management strategies for individuals in human care. Environment enrichment is a critical tool for promoting species typical behavior in human care; however, enrichment practices are often generalized and may not account for sex-specific differences. This study examined how sex, enrichment types, behaviors, and time of day influenced enrichment interaction duration in a small pride of African lions (n = 4) housed at the Columbus Zoo and Aquarium. Two enrichment types were evaluated: cognitive/occupational (CO, a manipulable barrel) …

Tick Lipocalin Triggers Mammalian Igfbp-3-Mediated Apoptosis In Macrophages And Keratinocytes, Krittika Nandy, P. P. Mahesh, Lichao Liu, Daniel E. Sonenshine, Hameeda Sultana, Girish Neelakanta

Biological Sciences Faculty Publications

Ticks secrete several molecules, including lipocalins, in their saliva during blood feeding on a vertebrate host. In this study, we provide novel evidence on the role of Ornithodoros turicata americanus tick lipocalin (Otlip) in modulating cytokine expression and in triggering apoptosis in mammalian macrophages and keratinocytes. The cytokine array analysis revealed significantly increased secretion of insulin-like growth factor-binding protein 3 (IGFBP3) from murine macrophage cell line upon treatment with recombinant Otlip protein (rGST-Otlip) when compared to the secretion noted from cells treated with a control protein (rGST). Similar observation with cytokine protein array analysis was noted when murine macrophages were …

Microarray Analysis Of Human Abdominal Aortic Aneurysm With Emphasis On Cardiovascular Genes Revealed Differentially Expressed Genes, Song Lu, Li Ping Li, John V. White, Xiaoying Zhang, Ifeyinwa Nwaneshiudu, Adaobi Nwaneshiudu, Nectaria Ntaoula, John Gaughan, Dimitri S. Monos, Wan-Lu Lin, Charalambos C. Solomides, Emilia L. Oleszak, Chris D. Platsoucas

Biological Sciences Faculty Publications

Background/Aim: We examined gene expression profiles in abdominal aortic aneurysm (AAA) lesions vs. normal aortas by cDNA microarray and real-time quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR).

Materials and Methods: Phosphorus (32P)-labeled cDNA from AAA specimens (mean AAA size 6.65 cm) and normal aortas were hybridized with a 588-gene microarray primarily of the cardiovascular system. The results were validated by qRT-PCR.

Results: A total of 35 out of the 588 genes were differentially expressed, with either log2 ratio of AAAs/controls ≥1 (upregulated; 20 genes) or ≤−1 (downregulated; 15 genes) in AAA lesions vs. normal aorta, and 25 of these were significantly …

Challenging And Diagnosing Structured Population Models By Testing Predictions From Stochastic Demography, Stephen P. Ellner, Robin E. Snyder, Daniel T. Blumstein, Dylan Z. Childs, Joshua C. Fowler, Christina M. Hernández, Julien G. A. Martin, María Paniw, Yngvild Vindenes

Biological Sciences Faculty Publications

1. Structured population models are parameterized to accurately project expected population sizes, stage/state distributions and population growth rates, but they also predict the variation in outcomes among individuals, such as the variance and skewness of lifetime reproductive output (LRO) and lifespan, the probability of never reproducing, and many other life-history metrics.

2. Testing such predictions about individual outcomes can be very useful model 'stress tests', because they depend on how components of the model (e.g. submodels for survival and fecundity) interact over multiple time steps, not just on the accuracy of the submodels. Because data on among-individual variation is rarely …

Predicting Oil Contamination In Water Using Machine Learning On Microbial Compositions, Tong Gao, Isaac Bigcraft, Stephen Techtmann, Issei Nakamura

Michigan Tech Publications

We present a compact and generative machine-learning framework that predicts oil contamination based on microbial community compositions from experimental samples. Our method combines dimensionality reduction with data augmentation and generative modeling to address high-dimensional, non-linear, and sparse microbial data. To reduce the 503-dimensional bacterial composition dataset, we compared three dimensionality reduction techniques: feature importance from random forest, principal component analysis (PCA), and t-distributed stochastic neighbor embedding (t-SNE). Feature importance outperformed PCA and t-SNE, improving predictive performance and identifying microbial species most strongly correlated with oil contamination. To mitigate data scarcity, we augmented the training data using an augmented data neural …

Cerebellar Motor And Non-Motor Contributions To Dystonia Pathophysiology And Treatment, Linda H Kim, Cheryl Brandenburg, Roy V Sillitoe

Duncan NRI Faculty and Staff Publications

Dystonia is a complex neurological disorder characterized by sustained or intermittent abnormal movements and/or postures. However, dystonia's non-motor symptoms, particularly the sleep disturbances, are critical yet underexplored concerns that affect all ages. Here, we synthesize current knowledge on the motor and non-motor domains of dystonia, emphasizing the functional interconnections and plasticity within cerebellar motor, cognitive, and sleep-associated circuits to motivate more comprehensive and effective treatments that improve overall quality of life.

Optimal Control Analysis Of Malaria Transmission In The Presence Of Insecticide Resistance And Climate Variability In Kenya, Lorna Chepkemoi, Titus Okello Orwa, Samuel Mwalili, Rachel Waema Mbogo, Steeven Belvinos Affognon, Daisy Salifu, Henri E.Z. Tonnang

All Peer-Reviewed Publications

Malaria remains a major public health concern in Kenya, where changing climatic conditions, insecticide resistance, and mosquito behavioral adaptations continue to challenge control efforts. This study develops and analyzes a climate-sensitive malaria transmission model that incorporates mosquito behavior, insecticide resistance, and vector–human ecological dynamics to identify optimal control strategies for the Kenyan context. The model’s well-posedness was established, the basic reproduction number (R0) computed using the next-generation matrix method, and the stability of equilibrium points assessed. Spatial analysis of R0 was performed using temperature and rainfall raster data to map transmission risk across Kenya under varying insecticide use scenarios. Results …

Behavioral And Electrophysiological Responses Of Fall Armyworm Larval Parasitoid Coccygidium Luteum To Maize And Companion Plant Volatiles, Emmanuel Peter, Sevgan Subramanian, Abdullahi Yusuf, Samira A. Mohamed, Baldwyn Torto, Emily A. Martin, Amanuel Tamiru

All Peer-Reviewed Publications

Companion cropping and biological control are among the best agronomic practices recommended for ecologically sustainable management of the invasive fall armyworm (FAW), Spodoptera frugiperda J.E. Smith (Lepidoptera: Noctuidae). Companion plants may suppress the FAW population by repelling the pest, disrupting host-plant location and recruiting biocontrol agents such as parasitoids. These interactions are primarily mediated by plant-derived volatile organic compounds (VOCs). Understanding parasitoids’ responses to VOCs emitted by companion plants enables selection of suitable cultivars to enhance biological control and design appropriate intercropping systems for effective FAW management. This study investigated behavioral and electrophysiological responses of a key FAW larval parasitoid, …

Taxonomy, Distribution And Ecology, Biology, Nutritional Composition, And Conservation Status Of Critically Endangered Lake Chala Tilapia Oreochromis Hunteri (Günther, 1889): Implications For Aquaculture Development, Jonathan Munguti, Mavindu Muthoka, Domitila Kyule, Esther Magondu, Jacob O. Iteba, Kevin Obiero, Paul Orina, Menaga Meenakshisundaram, Tanga M. Chrysantus

All Peer-Reviewed Publications

Oreochromis hunteri Günther, 1889, commonly known as Lake Chala tilapia, is an endemic cichlid restricted to the small crater lake, Lake Chala, on the border of Kenya and Tanzania. This review synthesizes existing knowledge on the taxonomy, and phylogenetic placement, distribution and ecology, and biology including nutritional composition, and conservation status of O. hunteri and identifies knowledge gaps to assess its potential for aquaculture development. The knowledge gaps include its reproductive biology, population structure, and adaptive capacity to environmental and climatic variability. As the type species of the genus Oreochromis, O. hunteri is a unique, genetically isolated lineage within a …

Insect Farming Innovations: A Pathway To Self-Reliance In Agrifood Systems In Africa, Zewdu Abro, Menale Kassie, Dennis Beesigamukama, Shaphan Yong Chia, Ermias Engida Legesse, Subramanian Sevgan, Julius Ecuru, Chrysantus M. Tanga

All Peer-Reviewed Publications

Insect farming as an innovative approach to transforming agrifood systems

Insect farming has emerged as a transformative and sustainable approach to addressing the interconnected challenges of food insecurity, environmental degradation, and economic vulnerability in Africa’s agrifood systems. By converting organic waste into high-value products (protein-rich feed, frass fertilizers, and bioactive compounds), insect farming offers an efficient circular economy solution that bridges nutrition, livelihoods, and ecological resilience (Lalander et al. 2025; Mei et al. 2024; Barragán-Fonseca et al. 2022; Xia et al. 2021; Van Huis 2020; Barragán-Fonseca et al. 2017; Van Huis and Oonincx 2017; Yi et al. 2014). Almost all …

Pathways, Outputs And Impact Of Nih-Supported Bioinformatics And Genomics Graduate Trainees In Africa, Daudi Jjingo, Andrew Walakira, Suhaila Hashim, Cisse Cheickna, Ronald Galiwango, Caleb Kibet, Florence N. Kivunike, Gerald Mboowa, Fredrick Elishama Kakembo, Babajide Ayodele, Jean Baka Domelevo Entfellner, Santie De Villiers, Karen Wambui, Segun Fatumo, Tinashe Chikowore, John Mukisa, Alfred Ssekagiri, Nicholas Bbosa, Julius Mulindwa, Samuel Kyobe, Mike Nsubuga, Grace Kebirungi, Eric Katagirya, Savannah Mwesigwa, Ibra Lujumba, Rogers Kamulegeya, Samuel Kirimunda, Stephen Kanyerezi, Shahiid Kiyaga, Ivan Sserwadda, Davis Kiberu, Daniel Masiga

All Peer-Reviewed Publications

Global biomedical and health research is increasingly relying on genomic and computational approaches, largely driven by the increasing volumes of nucleic acid sequencing. Concurrently, epidemiological studies and clinical records are generating enormous amounts of data amenable to disease modeling, machine learning, and artificial intelligence techniques. Bioinformatics and data science expertise is therefore essential for improved population health. Accordingly, in 2012, the US National Institutes of Health (NIH) in partnership with the Wellcome Trust, and with support from the African Society for Human Genetics, initiated the H3Africa (Human Heredity and Health in Africa) consortium. One of its key goals was to …

Ecological Intensification Of Maize-Kale Systems In Kenya By Biofertilization And Push-Pull Management Shifts Nematode Communities, Agnes Kiriga, Johnnie Van Den Berg, Frank Chidawanyika, Solveig Haukeland, Bianca Greyvenstein, Dennis Beesigamukama, Chrysantus M. Tanga, Sevgan Subramanian, Daniel M. Mutyambai

All Peer-Reviewed Publications

Plant-parasitic nematodes (PPNs) pose a persistent threat to vegetable production in Kenya, contributing to reduced yields and soil degradation. The management of PPNs in vegetables in Kenya has largely remained unaddressed. The integration of ecological intensification strategies such as the vegetable integrated push-pull (VIPP) system and the use of black soldier fly frass fertilizer (BSFF) is gaining traction in sustainable agriculture. The aim of this study was to determine the effects of integrating VIPP and BSFF on nematode abundance and diversity in maize-kale cropping systems. Field trials were conducted in two different agroecological zones in Kenya. Field treatments involved plots …

The Association Between Social Vulnerability And Racial Disparities In Preterm Birth, Anita Pershad, Gabby Adams, Lindsay Robbins, George Saade, Tetsuya Kawakita

Department of Obstetrics & Gynecology Faculty Publications

Objective

To evaluate the association between county-level social vulnerability and preterm birth and assess whether racial disparities vary across levels of vulnerability.

Methods

This cross-sectional study utilized restricted Centers for Disease Control and Prevention natality data from 2023. We included Black or White births with singleton pregnancies across 3123 US counties from 50 US states and the District of Columbia. Participants were grouped into quartiles based on the county-level Social Vulnerability Index (SVI), with quartile 4 representing the most socially vulnerable populations. The primary outcome was preterm birth, defined as delivery before 37 weeks. Secondary outcomes included small for gestational …

Brief Therapy Dog Interactions May Increase Self-Efficacy And Lower Perceived Stress And Cortisol In High School Students: A Preliminary Study, Dawn Melzer, Deirdre Yeater, Madison Derubis, Christiana Rose Kohlroser, Barbara J. Pierce

Psychology Faculty Publications

The present study examined changes in high schoolers’ perceived stress, general self-efficacy and cortisol levels after a brief interaction with a certified therapy dog. High school students completed self-report measures of perceived stress and general self-efficacy and provided salivary cortisol samples both before and after a 10-min interaction with a certified therapy dog. Following the interaction, students reported reductions in perceived stress scores, exhibited lower salivary cortisol concentrations and demonstrated increases in self-efficacy scores compared to before the interaction. Although higher self-efficacy scores were observed, general self-efficacy is generally regarded as a stable construct; therefore, these findings may reflect a …

Llamoco: Instruction Tuning Of Large Language Models For Optimization Code Generation, Zeyuan Ma, Yue-Jiao Gong, Hongshu Guo, Jiacheng Chen, Yining Ma, Zhiguang Cao

Research Collection School Of Computing and Information Systems

Recently, combining the strength of large language models (LLMs) and Evolutionary Computation (EC) has shown promising results for addressing optimization problems. It typically involves either iterative next-step solution seeking or directly prompting LLMs to generate critical optimization codes. However, these methods often suffer from low computational efficiency, high sensitivity to prompt design, and a lack of domain-specific knowledge. We introduce LLaMoCo, the first instruction-tuning framework designed to adapt LLMs for solving optimization problems in a code-to-code manner. LLaMoCo features a comprehensive instruction set that includes code-style problem descriptions as input prompts and robust optimization codes from expert EC optimizers as …

Graduate Student Retention: Examining Why Master’S Students Leave And What Motivates Their Return In A Large Public University System, Sonja Prophete

Theses and Dissertations

Graduate student persistence is a relatively unexplored area in the literature of higher education studies; specifically, at a multi-institutional scale at the master's level. This research study examines the factors which cause students to discontinue their master's degrees, and what conditions could possibly support them returning to their program at a large urban public university system. The current study was guided by Hoyt and Winn's (2004) distinction between non-returning students, and Bean & Metzner's (1985) theoretical model of student attrition. A sequential mixed-methods study was conducted to examine the institutional and environmental influences on students' decision-making processes.

The quantitative data …

The Gendered Path Of Least Resistance: First Entry And Exit Behaviors Of Public And Nonprofit Employees, Tiana Marrese, Ying Liu, Femida Handy

Political Science Faculty Publications

Public and nonprofit organizations exhibit high rates of female employment often attributed to sector structures and social roles. To better understand how individual behaviors dynamically contribute to these distinctive ratios, we deconstruct public and nonprofit employment into gendered patterns of attraction and attachment. Using duration analysis and following a cohort from the National Longitudinal Survey of Youth 1997, this research finds that women demonstrate a higher attraction to their first public and nonprofit job compared to men, evidenced through a faster rate of entry into this employment. There are no significant gender differences when considering the duration of an individual's …

All-Inside Arthroscopic Technique For Repairing Radial Meniscus Tears At The Anterior Horn-Body Junction, Brandon Omari Boyd, Robert M. Walker, Harrison A. Volaski, Ferdinand J. Chan

Department of Medicine Faculty Publications

Radial meniscus tears are a common tear pattern that, if left untreated, can ultimately lead to accelerated degenerative changes and disability. There is well-established evidence that supports meniscal preservation in patients with radial meniscus tears. Various surgical techniques are used to repair radial tears, including inside-out, outside-in, and all-inside methods. Self-retrieving all-inside devices are a safe option when repairing radial tears. However, radial tears at the junction of the anterior horn and body present a unique surgical challenge, as surgeons may have difficulty maneuvering the jaws of the self-retrieving suture device around the anterior limb of the meniscal tear. We …

Recent Technological Advances In Monitoring And Neuromodulation Of Non-Malignant And Neurogenic Bladder Conditions, Chang Liu, Yifan Wang, Mario Romero-Ortega, Argyrios Stampas, Yingchun Zhang, Philippe Zimmern, Zhengwei Li

Faculty, Staff and Student Publications

Neurogenic bladder and lower urinary tract (LUT) dysfunctions encompass a wide variety of urinary disorders resulting from nervous system impairments. Unfortunately, conventional treatments are still limited and can have significant complication rates, especially when stent implantations or other surgical procedures are involved. Therefore, there is a critical need to develop novel therapeutic strategies and pharmacological approaches to address these challenging urological conditions. Recent technological advances offer promising solutions to overcome some of these challenges faced by patients with bladder and LUT dysfunction. This review summarizes recent progress in advanced urotechnologies, focusing on bladder monitoring and neuromodulation approaches, advanced medical instruments …

Environmental Load In Technology-Rich Classrooms: A Practitioner Reflection On Student Attention, Cognitive Fatigue, And Instructional Design, Christopher Morales

Essays in Education

This practitioner essay examines student disengagement in technology-rich classrooms through the lens of cognitive load and environmental demand. Rather than interpreting all off-task behavior as laziness, avoidance, or lack of motivation, the essay argues that some students may be responding to cumulative overload created by screens, transitions, digital platforms, visual clutter, noise, lighting, and fragmented instructional routines. Drawing from classroom observation and cognitive load theory, the essay introduces environmental load as a practical concept for educators seeking to preserve student attention without lowering academic expectations. The essay offers reflective questions and instructional adjustments that can help teachers and school leaders …

No Groundwater, No Fish: The Critical Role Of Groundwater In Supporting Non-Glacial, Salmon-Bearing Rivers In South-Central Alaska, Tyelyn Brigino, Kai Rains, Edgar Guerron-Orejuela, Jacob Argueta, Syverine Bentz, Coowe Walker, Mark Rains

School of Geosciences Faculty and Staff Publications

Groundwater discharge plays an important role in the hydrologic and ecologic functioning of rivers including sustaining streamflow and related habitat year-round. Simultaneously, groundwater supports the increasing demands of people as the global population continues to grow. Balancing the needs of users becomes increasingly important as climate change introduces greater uncertainty in water resources and fisheries, especially for economically important anadromous species that depend on freshwater resources. We investigated the seasonal and regional variability of groundwater contributions to six non-glacial mainstem salmon-bearing rivers in south-central Alaska. We hypothesized that groundwater contributes more than half of the annual streamflow, and nearly all …