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Articles 29371 - 29400 of 36199
Full-Text Articles in Entire DC Network
The Role Of Cd5 In Experimental Autoimmune Encephalitomyelitis, Robert C. Axtell
The Role Of Cd5 In Experimental Autoimmune Encephalitomyelitis, Robert C. Axtell
All ETDs from UAB
The regulation of activation, differentiation and persistence of effector T-cells are critical for the development of Experimental Autoimmune Encephalomyelitis (EAE), the animal model of Multiple Sclerosis. Until now, the function of CD5 was accepted to be a negative regulator of T-cell activation. This dissertation reports that CD5 has an addi-tional role in T-cell responses, which is to promote cell survival. Observations from EAE experiments revealed that mice deficient in CD5 exhibited decreased disease severity which was associated with the inability of activated T-cells to survive. Moreover, block-ing the engagement of CD5 in mice led to enhanced activation induced cell death …
Cd8+ T-Lymphocytes And The Control Of Cytomegalovirus Infection Of The Newborn Central Nervous System, Glenn Robert Burgner Bantug
Cd8+ T-Lymphocytes And The Control Of Cytomegalovirus Infection Of The Newborn Central Nervous System, Glenn Robert Burgner Bantug
All ETDs from UAB
Congenital HCMV infection of the developing brain is the leading viral cause of mental retardation and sensorineural hearing loss. To elucidate the pathogenesis of congenital HCMV CNS infections, we developed a small animal model of CMV infection where newborn Balb/c mice are peripherally inoculated with murine cytomegalovirus. In this model we observed transient deficits in cerebellar/hindbrain development as well as the recruitment of peripheral immune effector cells to the CNS parenchyma. CD8+ T-lymphocytes were the predominant mononuclear cellular infiltrates in the brain and immune-depletion of CD8+ cells resulted in increased viral genome copy numbers in the CNS. CD8+ T-lymphocytes exhibited …
Learning With Meaning: A Case Study Of The Use Of Engaging Instruction In A Suburban School District In The Southeastern United States, Esther Ruth Beenken
Learning With Meaning: A Case Study Of The Use Of Engaging Instruction In A Suburban School District In The Southeastern United States, Esther Ruth Beenken
All ETDs from UAB
This qualitative case study was conducted to explore educators’ perceptions of the implementation of Engaging Instruction in a suburban school district in the Southeastern United States. It addresses gaps in the literature regarding Engaging Instruction and discusses current research. It highlights implementation, use of design qualities, innovative teaching, student empowerment, change, and the challenges of Engaging Instruction. The theoretical framework that guided this study included the research and the writing of Phillip Schlechty, Shaking up the Schoolhouse (2001) and Inventing Better Schools (1997). His theory of Engaging Instruction addresses student engagement with a student-oriented philosophy of teaching. This philosophy encourages …
Green Tea Polyphenols Are Associated With Changes In Genetic And Epigenetic Anti-Cancer Mechanisms In Vitro And In Vivo, Joel Bradford Berletch
Green Tea Polyphenols Are Associated With Changes In Genetic And Epigenetic Anti-Cancer Mechanisms In Vitro And In Vivo, Joel Bradford Berletch
All ETDs from UAB
Human chromosomes are protected from degradation associated with cell division by hexameric repeats of 5’-TTAGGG-3’ termed telomeres. During cellular replication human chromosomes undergo the loss of up to 300 bp of DNA with each division, reaching a critical length which leads to senescence and apoptosis. Most cancer cells bypass this lifespan regulatory mechanism by the expression of telomerase, a protein complex that adds telomeres through the reverse transcriptase activity of its catalytic subunit, hTERT. Approximatly 90% of all cancers express the hTERT gene making it an attractive target for novel cancer therapies. The objective of this dissertation was to help …
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta
All ETDs from UAB
Persistent infection with certain “high-risk” types of human papillomavirus (HPV) infection is central to the development of cervical cancer. Human immunodeficiency virus (HIV)-infected women are at a higher risk of HPV infection, high grade cervical intraepithelial lesions, and cervical cancer. This study examined type-specific distribution of prevalent and incident HPV infections, clearance rates, and associated factors using novel molecular assays for HPV detection and genotyping in a cohort of 280 HIVinfected women in Alabama. First, we described the cohort’s sociodemographic characteristics and behavioral risk profile for HIV and other sexually transmitted infections, and assessed the factors associated with HIV-1 viral …
A Dental Student At Work In The School Of Dentistry Clinic, Circa 1958, Uab Archives
A Dental Student At Work In The School Of Dentistry Clinic, Circa 1958, Uab Archives
Images of the Month from UAB Archives
Image ID: P11, #033
A dentistry student works on a patient
December 18, 2006 Reporter, University Of Alabama At Birmingham
December 18, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
December 4, 2006 Reporter, University Of Alabama At Birmingham
December 4, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
University Hospital, Circa 1967, Uab Archives
University Hospital, Circa 1967, Uab Archives
Images of the Month from UAB Archives
Image ID: P7.3.5: #092
Outside of University Hospital decordated with greenery
November 20, 2006 Reporter, University Of Alabama At Birmingham
November 20, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
November Photo Op: Uab's Jefferson Tower Lights Up Pink And Blue, Celebrating Prematurity Awareness Month, Staff
Browse All News
No abstract provided.
November 6, 2006 Reporter, University Of Alabama At Birmingham
November 6, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
The Uab Mascot Entertains Fans At A Blazer Basketball Game, Circa 1981, Uab Archives
The Uab Mascot Entertains Fans At A Blazer Basketball Game, Circa 1981, Uab Archives
Images of the Month from UAB Archives
Image ID: P6, #001
A rooster mascot shows an eye chart to the crowd at a basketball game
Suits 4 Success, Staff
Jim 'N Nick's, Uab Angel Squad Team Up For Breast Cancer Education, Staff
Jim 'N Nick's, Uab Angel Squad Team Up For Breast Cancer Education, Staff
Browse All News
No abstract provided.
October 16, 2006 Reporter, University Of Alabama At Birmingham
October 16, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Uab's Brian F. Geiger Named Health Educator Of The Year, Staff
Uab's Brian F. Geiger Named Health Educator Of The Year, Staff
Browse All News
No abstract provided.
Uab School Of Business Featured In "Best 282 Business Schools", Staff
Uab School Of Business Featured In "Best 282 Business Schools", Staff
Browse All News
No abstract provided.
Feldman Named Clear Director, Staff
Uab Study To 'Adapt' To Treat High Blood Pressure, Staff
Uab Study To 'Adapt' To Treat High Blood Pressure, Staff
Browse All News
No abstract provided.
October 2, 2006 Reporter, University Of Alabama At Birmingham
October 2, 2006 Reporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Uab Nursing - Fall 2006, University Of Alabama At Birmingham
Uab Nursing - Fall 2006, University Of Alabama At Birmingham
UAB Nursing magazine
No abstract provided.
Directions - Fall 2006, Mervyn H. Sterne Library
Directions - Fall 2006, Mervyn H. Sterne Library
Directions (Sterne Library, 1985-2015)
No abstract provided.
Commencement Ceremony For The Medical College Of Alabama, October 25, 1946, Uab Archives
Commencement Ceremony For The Medical College Of Alabama, October 25, 1946, Uab Archives
Images of the Month from UAB Archives
Image ID:
A male and female graduate look at a degree
Uab Launches Promising Brain Tumor Trial, Staff
Street, Till In New Community Affairs Posts At The Uab Comprehensive Cancer Center, Staff
Street, Till In New Community Affairs Posts At The Uab Comprehensive Cancer Center, Staff
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No abstract provided.
Short Film By Uab Student Honored At Sidewalk Film Festival, Staff
Short Film By Uab Student Honored At Sidewalk Film Festival, Staff
Browse All News
No abstract provided.
Uab Home To Advanced Center For Parkinson's Research, Staff
Uab Home To Advanced Center For Parkinson's Research, Staff
Browse All News
No abstract provided.
Uab Hospital 'Consumer's Choice', Staff
Fillingim Wins Uab Distinguished Alumni Prize In Psychology, Staff
Fillingim Wins Uab Distinguished Alumni Prize In Psychology, Staff
Browse All News
No abstract provided.