Digital Commons Network^™

Predicting Success Or Failure Of Immunotherapy For Cancer: Insights From A Clinically Applicable Mathematical Model, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

The objective of this study was to create a clinically applicable mathematical model of immunotherapy for cancer and use it to explore differences between successful and unsuccessful treatment scenarios. The simplified predator-prey model includes four lumped parameters: tumor growth rate, g; immune cell killing efficiency, k; immune cell signaling factor, λ; and immune cell half-life decay, μ. The predator-prey equations as functions of time, t, for normalized tumor cell numbers, y, (the prey) and immunocyte numbers, x, (the predators) are: dy/dt = gy – kx and dx/dt = λxy – μx. A parameter estimation procedure that capitalizes on available clinical …

An Analysis Of Step, Jt, And Pdf Format Translation Between Constraint-Based Cad Systems With A Benchmark Model, Dillon Mckenzie-Veal

Department of Computer Graphics Technology Degree Theses

This research was conducted to provide greater depth into the ability of STEP AP 203 Edition 2, JT, and 3D PDF to translate and preserve information while using a benchmark model. The benchmark model was designed based on four industry models and created natively in the five industry leading 3D CAD programs. The native CAD program models were translated using STEP, JT, and 3D PDF. Several criteria were analyzed along the paths of translation from one disparate CAD program to another. Along with the analysis of the three interoperable file formats a survey was conducted to determine how well the …

Social Media Marketing In A Small Business: A Case Study, Sarah Cox

Department of Computer Graphics Technology Degree Theses

In today’s social media driven environment, it is essential that small businesses understand Facebook, Twitter, and the strategies behind using social media for growing their business. Unfortunately, many small businesses do not have a strategy when they begin using social media. The purpose of this study is to understand how the owner of a small business, recognized for using social media to grow the business, uses social media to engage consumers. A case study is presented, followed by an in-depth interview with the small business owner, and accompanied by an analysis of the business’s Facebook and Twitter posts. The results …

Developing A Forensic Method Of Acquisition And Analysis Of The Motorola Xoom Tablet, Justin A. Tolman

Purdue Polytechnic Masters Theses

There is currently no forensically sound method for analyzing the Motorola Xoom tablet. The purpose of this research is to determine whether a forensically sound method can be developed for the Motorola Xoom tablet running the Ice Cream Sandwich Android operating system. This research is important for investigators as the more forensically sound method offers greater protection relating to an individual’s privacy rights. Furthermore, tablets are a relatively new form of digital devices that are rising quickly in the public. This research sets the groundwork for investigating tablets in a forensically sound manner. The tablet is used in such a …

Frequent Flier Perceptions And Air Travel Satisfaction: The Airline Passenger Survey 2012, Erin E. Bowen, Brent D. Bowen, Dean E. Headley

Airline Passenger Surveys

The Airline Passenger Survey is an annual survey of frequent fliers who visit the web site for the Airline Quality Rating. Since 2009, over 4,000 passengers have responded to researchers’ request to provide a consumer perspective on the quality of today’s air travel experience. Airline Quality Rating researchers at Purdue University and Wichita State University compare the consumer experience of air travel with the objective rankings of the Airline Quality Rating (www.airlinequalityrating.com). These detailed findings are provided publicly and periodically released to the media.

Experimental Assessment Of Metal Foam And Louvered Fins As Air-Side Heat Transfer Enhancement For Miniaturized Condensers, Guilherme Borges Ribeiro, Jader Barbosa Jr.

International Refrigeration and Air Conditioning Conference

An experimental investigation was conducted to evaluate and compare the thermal-hydraulic performances of crossflow microchannel condensers using louvered fins and metal foams as extended surfaces. Three copper foam surfaces with pore densities of 10 and 20 PPI and porosities of 89.3% and 94.7% were compared with three aluminum louvered fins with lengths of 27 and 32 mm (in the flow direction) and heights of 5 and 7.5 mm. The experiments were carried out in a closed loop wind-tunnel calorimeter equipped with a R-600a refrigeration loop. A condensing temperature of 45°C was used in all tests, with face velocities ranging from …

Simultaneous Heat And Mass Transfer In A Wetted Heat Exchanger, Part I: Experiments, Feini Zhang, Jessica Bock, Anthony M. Jacobi, Hailing Wu

International Refrigeration and Air Conditioning Conference

Using an induced open-loop wind tunnel and a full cone water spray nozzle, the performance of a brazed aluminum heat exchanger with louvered fins is studied experimentally for wet conditions. The total capacity, pressure drop and water drainage behavior under various water usage rates and air face velocities are explored and compared to dry-condition data. The impact on spray orientation is also studied. The results are presented as plots of performance against water usage rate or water spray rate per unit heat transfer area. Fouling on the fin surface was observed in the experiment, and fouling distribution characteristics are discussed …

Thermal-Hydraulic Performance Of Metal Foam Heat Exchangers, Kashif Nawaz, Jessica Bock, Anthony M. Jacobi

International Refrigeration and Air Conditioning Conference

Due to their large surface-area-to-volume ratio and tortuous structure, metal foams hold promise for heat transfer applications. Both of these factors increase the heat transfer by enhancing the mixing and surface area. The main disadvantage associated with their thermal-hydraulic performance is relatively higher pressure drop, resulting in larger pumping power requirements if they are used in a heat exchanger. In this paper, open-cell aluminum metal foam is considered as a highly compact replacement for conventional fins in brazed aluminum heat exchangers. SEM techniques are used to characterize the foam characteristics such as pore and ligament diameter. Experiments are conducted by …

Dual-Mode Wicking Structures For Enhanced Evaporative Heat Transfer, Shankar Krishnan, Ward E. Tegrotenhuis

International Refrigeration and Air Conditioning Conference

This paper reports on conceptual design and thermo-fluid characteristics of two-phase flow devices enabled by dualmode wicks. In dual-mode wicking structures, liquid and vapor flow paths are integrated on the same plane and segregated flow of the two-phases is achieved by having networks of pores of multiple length-scales. When a mixture of a gas and a liquid flow through this media and the wick material wets the liquid, then the liquid will preferentially segregate to and flow through the mode with the smaller effective pore size. The gas will flow through the paths with the larger effective pore size. These …

Security Implications Of The Cisco Nexus 1000v, Benjamin D. Peterson

Purdue Polytechnic Masters Theses

Virtualization is a technology that has become increasingly popular with those wishing to reduce the energy consumption of their datacenters. This is especially true since virtualization technology allows multiple physical servers to be consolidated onto a single physical server in the form of virtual machines. Virtual networking devices have been created to allow these virtual machines to communicate amongst each other and with outside networks. Initially these virtual networking devices were crude; however, partnerships such as the one between Cisco and VMware have led to products such as the Nexus 1000V that have improved this network functionality. Despite the creation …

Biology And Nursing Students’ Perceptions Of A Web-Based Information Literacy Tutorial, Sharon A. Weiner, Nancy Pelaez, Karen Chang, John M. Weiner

Libraries Faculty and Staff Scholarship and Research

This study examined the perceptions of two groups of students to obtain different perspectives on the online information literacy tutorial, CORE (Comprehensive Online Research Education, to plan for its update. The CORE tutorial includes seven modules: “Planning Your Project,” “Topic Exploration,” “Types of Information,” “Search Tools,” “Search Strategies,” “Evaluating Sources,” and “Copyright, Plagiarism, and Citing Sources.” First-year students in biology and nursing courses responded to a survey after completing the CORE modules. Students indicated that they liked learning through an online tutorial. However, they thought that the tutorial could be improved with shorter modules and the addition of video and …

Middle Managers And Major Gifts: Fundraising For Academic Librarians, Tomalee Doan

Libraries Faculty and Staff Scholarship and Research

Abstract

Purpose: Share successful strategies for mid-level management academic librarians and archivists for raising major gifts from individual donors

Design: Demonstrate growing need for fundraising in university libraries and participating in fundraising activities as an increasing expectation of librarians; provide case studies of successful fundraising by librarian and archivist including their work with donors and collaboration with development professionals; conclude with suggestions for maintaining donor relations

Findings: Fundraising is increasingly rapidly as an expected activity of librarians but a slowly growing part of their education. More literature is also needed on the topic. Successful fundraising is dependent …

Knowledge-Enabled Engineering Design: Toward An Integrated Model, Michael Fosmire, David Radcliffe

Libraries Faculty and Staff Scholarship and Research

Librarians and engineering faculty have long understood that design is one of the defining processes of the engineering profession. In an increasingly knowledge-driven society, students need to efficiently locate, assess and integrate relevant information into their design process so that they can develop innovation solutions to emerging complex, global grand challenges. Increasingly, engineering curricula are incorporating design as early as the first year, but a question remains as to how effectively information literacy is being integrated into these early experiences of design. For example, the Engineering Change study found there has been very little improvement to lifelong learning skills in …

The Librarian And The Designer: Working Together To Create A Showcase For Contemporary Learning, Tomalee Doan

Libraries Faculty and Staff Scholarship and Research

Many institutions of higher education are designing spaces that reflect the established correlation between learning spaces and student achievement, mastery, and retention (Hunley & Schaller, 2006). In this case study of a renovation of an 18,327 square foot business library space into a dynamic learning environment, Melinda McGee, the Interior Designer for the project, and Tomalee Doan, the Associate Professor and Head Librarian of the business library, share the experience of their successful partnership that required a creative and an in-depth collaboration with each other and with several other stakeholders not usually found in an academic setting. Their goal is …

Information Literacy Beyond The Library: Organizations To Watch, Sharon A. Weiner

Libraries Faculty and Staff Scholarship and Research

The need for an information-literate society is increasingly apparent to educators, employers, policy makers, and other leaders. Colleges and undergraduate libraries are well positioned to collaborate with a variety of constituencies on addressing this need. Academic librarians can benefit from an awareness of reports, conferences, and newsletters of organizations outside of libraries that recognize the importance of effectively finding, using, and communicating information. This column describes four organizations. By examining the Websites and subscribing to the online updates for each, librarians can have current information about topics that relate to information literacy and incorporate it into their libraries’ information literacy …

Solid State Microchp Based On Thermophotovoltaic And Thermoelectric Conversion, William M. Worek, Christopher Brown, Rebecca Trojanowski, Thomas Butcher, Edward Horne

International Refrigeration and Air Conditioning Conference

MicroCHP involves the coproduction of both heat and electric power in (typically) residential heating systems. A range of different energy conversion technologies are currently receiving attention for this application including Stirling engines, internal combustion engines, fuel cells, and Rankine cycles with steam or organic compounds as working fluids. In this work the use of ThermoPhotoVoltaic (TPV) and ThermoElectric (TE) conversion devices either alone or in combination for power production in an oil-fired heating system have been explored. The focus of this work to date has been on sufficient electric power output to achieve self-powering of the appliance with the consideration …

Characteristics Of R718 Thermocompression Refrigerating / Heat Pump Systems With Two-Phase Ejectors, Vasko Nikola Sarevski, Milan Nikola Sarevski

International Refrigeration and Air Conditioning Conference

The paper describes the investigations of the R718 thermocompression refrigerating cycle with two-phase ejector as a compression device. The complex thermal and flow phenomena connected with compression and condensation inside the two-phase ejector flow field are investigated and performance characteristics are estimated. The thermodynamic processes are shown in pressure – enthalpy and temperature – entropy diagrams. Based on the described thermodynamic model, a computational procedure was generated to evaluate the performance characteristics of this R718 refrigerating system. The implementation of the proposed R718 twophase ejector refrigerating / heat pump systems for utilization of low temperature heat and waste heat is …

Cooling Performance Improvement Of The Heat Driven Type Metal Hydride Refrigerator-Heat Transfer Enhancement Influence Of Metal Hydride Sheet Loading Into A Metal Hydride Particle Bed, Sangchul Bae, Masafumi Katsuta, Ikuto Homma, Eiji Morita

International Refrigeration and Air Conditioning Conference

In the refrigeration and air conditioning fields, the demands of energy conservation and renewable energy have been increased recently. In this study, we aim at the development of the heat driven type metal hydride (abbr., MH) that can be driven by the low temperature exhaust or solar heat under 100ᵒC. In order to use this system commercially, heat transfer enhancement of MH particle bed, activation characteric improvement and production cost reduction of MH must be achieved. In this study, we use the two heat transfer enhancement methods for improving the low effective thermal conductivity of MH particle bed. One is …

Compact High Efficiency Adsorption Heat Pump, Ward E. Tegrotenhuis, Paul H. Humble, Josh B. Sweeney

International Refrigeration and Air Conditioning Conference

An innovative adsorption cycle heat pump technology is presented that is compact and capable of achieving high energy efficiency for integrated space heating, air conditioning, and water heating. High energy efficiency is accomplished by effectively recuperating heat within the system to minimize energy consumption. This substantially reduces the thermodynamic losses that occur when the sorbent beds are thermally cycled without effective heat recuperation. Furthermore, equipment cost is reduced by thermally cycling the sorbent beds very rapidly using embedded microchannel heat exchangers, which reduces size and cost of the beds. Performance of the cycle is assessed for ammonia refrigerant and carbon …

Resolving Structure And Mechanical Properties At The Nanoscale Of Viruses With Frequency Modulation Atomic Force Microscopy, David Martinez-Martin, Carolina Carrasco, Mercedes Hernando-Pérez, P. J. De Pablo, Júlio Gómez-Herrero, Rebeca Pérez, Mauricio Garcia Mateu, José López Carrascosa, Daniel Roy Kiracofe, John C. Melcher, Arvind Raman

School of Mechanical Engineering Faculty Publications

Structural Biology (SB) techniques are particularly successful in solving virus structures. Taking advantage of the symmetries, a heavy averaging on the data of a large number of specimens, results in an accurate determination of the structure of the sample. However, these techniques do not provide true single molecule information of viruses in physiological conditions. To answer many fundamental questions about the quickly expanding physical virology it is important to develop techniques with the capability to reach nanometer scale resolution on both structure and physical properties of individual molecules in physiological conditions. Atomic force microscopy (AFM) fulfills these requirements providing images …

Open-Cell Metal Foams For Use In Dehumidifying Heat Exchangers, Xiaohong Han, Nawaz Kashif, Jessica Bock, Anthony M. Jacobi

International Refrigeration and Air Conditioning Conference

Metal foams with an open-cell structure have physical and mechanical properties suggesting they might have advantages over conventional fin materials for use in air-cooling heat exchangers. For example, metal foams are low weight, have high to very high specific surface area (up to over 10000 m2/m3), have high gas permeability, and have relatively high thermal conductivity (for open-cell bodies). Due to these properties, open-cell metal foams have been studied for many heat transfer applications, especially as a material for constructing efficient compact heat exchangers. In this work, dynamic dips tests are undertaken to explore the water-drainage behavior of the metal …

Exergy Analysis Of An Absorption Refrigeration System Using An Iconic Liquid As A Working Fluid In The Chemical Compressor, Yoon Jo Kim, Sarah Kim, Yogendra K. Joshi, Andrei G. Fedorov, Paul A. Kohl

International Refrigeration and Air Conditioning Conference

The first and second law of thermodynamics are applied to an ionic-liquid (IL) based absorption refrigeration system for high power electronics cooling. The IL is a salt in a liquid state usually with an organic cation and inorganic anion. It provides an alternative to the normally toxic working fluids used in the chemical compression loop, such as ammonia in conventional absorption systems. The use of ILs also eliminates crystallization and metal-compatibility problems of the water/LiBr system. In this study, mixtures of refrigerants and imidazolium-based ILs are theoretically explored as the working fluid pairs in a miniature absorption refrigeration system, so …

Preliminary Study Of A Novel Compact R718 Water Chiller With Integration Of A Single Stage Centrifugal Compressor And Two-Phase Ejectors, Milan Nikola Sarevski, Vasko Nikola Sarevski

International Refrigeration and Air Conditioning Conference

A novel compact R718 water chiller with integration of a centrifugal compressor stage and two phase ejectors as a second stage compression device is proposed. The paper describes the investigations of this R718 refrigerating cycle. The limitations of the R718 centrifugal compressor stage pressure ratio are discussed, and possibilities for introduction of two-phase ejectors in the R718 refrigerating systems with direct evaporation and condensation are analyzed. The complex thermal and flow phenomena connected with additional compression, desuperheating and condensation inside the two-phase ejector flow field are investigated and performance characteristics are estimated. The thermodynamic processes are shown in pressure – …

Development Of Suction Pipe Design Criterion To Secure Oil Return To Compressor, Tiandong Guo, Jin Yong Jang, Sangchul Do, Ji Hwan Jeong, Bongjun Choi

International Refrigeration and Air Conditioning Conference

In the present work, phenomena associated with counter current flow limitation (CCFL) were experimentally investigated using small diameter tubes in order to suggest criterion for which the oil return is secured. The test section is made of Pyrex glass tube to allow visual observation. The inner diameter of the test tube is 7mm and the height is 1m. The inclination of test tubes varied from vertical to crank type with various horizontal lengths. Waterair flow and lubricant oil-air flow were examined through a series of experiment at various liquid flow rates. In this experimental study, flow reversal and flooding phenomena …

Bibliography For The Study Of Text And Image In Modern European Culture, Natasha Grigorian

CLCWeb Library

No abstract provided.

Wandering On The Web-Free Cloud Storage, Amy J.W. Slowik

Against the Grain

No abstract provided.

Listening To Revise: What A Study About Text-To-Speech Software Taught Us About Students' Expectations For Technology Use In The Writing Center, Tammy Conard-Salvo, John M. Spartz

The Writing Center Journal

No abstract provided.

Information For Authors

The Writing Center Journal

No abstract provided.

Bringing Balance To The Table: Comprehensive Writing Instruction In The Tutoring Session, Bethany Bibb

The Writing Center Journal

No abstract provided.

Announcements

The Writing Center Journal

No abstract provided.