Digital Commons Network^™

A Comparative Study Of Two Prediction Models For Brain Tumor Progression, Deqi Zhou, Loc Tran, Jihong Wang, Jiang Li, Karen O. Egiazarian (Ed.), Sos S. Agaian (Ed.), Atanas P. Gotchev (Ed.)

Electrical & Computer Engineering Faculty Publications

MR diffusion tensor imaging (DTI) technique together with traditional T1 or T2 weighted MRI scans supplies rich information sources for brain cancer diagnoses. These images form large-scale, high-dimensional data sets. Due to the fact that significant correlations exist among these images, we assume low-dimensional geometry data structures (manifolds) are embedded in the high-dimensional space. Those manifolds might be hidden from radiologists because it is challenging for human experts to interpret high-dimensional data. Identification of the manifold is a critical step for successfully analyzing multimodal MR images.

We have developed various manifold learning algorithms (Tran et al. 2011; Tran et al. …

A Pharmacology-Based Enrichment Program For Undergraduates Promotes Interest In Science, Elizabeth A. Godin, Stephanie V. Wormington, Tony Perez, Michael M. Barger, Kate E. Snyder, Laura S. Richman, Rochelle Schwartz-Bloom, Lisa Linnenbrink-Garcia

Educational Leadership & Workforce Development Faculty Publications

There is a strong need to increase the number of undergraduate students who pursue careers in science to provide the “fuel” that will power a science and technology–driven U.S. economy. Prior research suggests that both evidence-based teaching methods and early undergraduate research experiences may help to increase retention rates in the sciences. In this study, we examined the effect of a program that included 1) a Summer enrichment 2-wk minicourse and 2) an authentic Fall research course, both of which were designed specifically to support students' science motivation. Undergraduates who participated in the pharmacology-based enrichment program significantly improved their knowledge …

Liver Perilipin 5 Expression Worsens Hepatosteatosis But Not Insulin Resistance In High Fat-Fed Mice, Michelle B. Trevino, David Mazur-Hart, Yui Machida, Timothy King, Joseph Nadler, Elena V. Galkina, Arjun Poddar, Sucharita Dutta, Yumi Imai

Mathematics & Statistics Faculty Publications

Perilipin 5 (PLIN5) is a lipid droplet (LD) protein highly expressed in oxidative tissues, including the fasted liver. However, its expression also increases in nonalcoholic fatty liver. To determine whether PLIN5 regulates metabolic phenotypes of hepatosteatosis under nutritional excess, liver targeted overexpression of PLIN5 was achieved using adenoviral vector (Ad-PLIN5) in male C57BL/6J mice fed high-fat diet. Mice treated with adenovirus expressing green fluorescent protein (GFP) (Ad-GFP) served as control. Ad-PLIN5 livers increased LD in the liver section, and liquid chromatography with tandem mass spectrometry revealed increases in lipid classes associated with LD, including triacylglycerol, cholesterol ester, and phospholipid classes, …

Interactive Effects Of Climate Change With Nutrients, Mercury, And Freshwater Acidification On Key Taxa In The North Atlantic Landscape Conservation Cooperative Region, Alfred E. Pinkey, Charles T. Driscoll, David C. Evers, Michael J. Hooper, Jeffrey Horan, Jess W. Jones, Rebecca S. Lazarus, Harold G. Marshall, Andrew Milliken, Barnett A. Rattner, John Schmerfold, Donald W. Sparling

Biological Sciences Faculty Publications

The North Atlantic Landscape Conservation Cooperative LCC (NA LCC) is a public-private partnership that provides information to support conservation decisions that may be affected by global climate change (GCC) and other threats. The NA LCC region extends from southeast Virginia to the Canadian Maritime Provinces. Within this region, the US National Climate Assessment documented increases in air temperature, total precipitation, frequency of heavy precipitation events, and rising sea level, and predicted more drastic changes. Here, we synthesize literature on the effects of GCC interacting with selected contaminant, nutrient, and environmental processes to adversely affect natural resources within this region. Using …

Protein Recycling In Bering Sea Algal Incubations, Eli K. Moore, H. Rodger Harvey, Jessica F. Faux, David R. Goodlett, Brook L. Nunn

OES Faculty Publications

Protein present in phytoplankton represents a large fraction of the organic nitrogen and carbon transported from its synthesis in surface waters to marine sediments. Yet relatively little is known about the longevity of identifiable protein in situ, or the potential modifications to proteins that occur during bloom termination, protein recycling and degradation. To address this knowledge gap, diatom-dominated phytoplankton was collected during the Bering Sea spring blooms of 2009 and 2010, and incubated under darkness in separate shipboard degradation experiments spanning 11 and 53 d, respectively. In each experiment, the protein distribution was monited over time using shotgun proteomics, …

The Influence Of Shelter, Conspecifics, And Threat Of Predation On The Behavior Of The Long-Spined Sea Urchin (Diadema Antillarum), Meredith D. Kintzing, Mark J. Butler Iv

Biological Sciences Faculty Publications

The interplay of competition and predation often affects prey habitat use, which may concentrate prey in safer areas with indirect consequences on their foraging efficiency and the effects of their foraging on the community. Predation is intense on coral reefs where competition for limited space and food is severe. The sea urchin Diadema antillarum, an inhabitant of Caribbean coral reefs, uses crevice shelters and often aggregates with conspecifics for protection against predators, which appears to reflect a conflicting balance between group defense versus competition for limited shelter. A series of laboratory experiments was used to determine how the availability of …

Graduate News, Office Of Graduate Studies, Old Dominion University

Graduate News

October/November 2014 issue of Graduate News from the Office of Graduate Studies (now, ODU Graduate School).

Editor And Journal Information

Virginia Journal of Science

Editor and journal information from Virginia Journal of Science, vol. 65, no. 3 & 4, Fall/Winter 2014

Circulation, Vol. 20, No. 1, Center For Coastal Physical Oceanography, Old Dominion University, Teresa Updyke

CCPO Circulation

Fall 2014 issue of CCPO Circulation featuring article "Surface Current Mapping Using Radar Technology" by Teresa Updyke.

A Comparison Of Techniques Measuring Stress In Birds, Deborah A. O'Dell, Michael A. Carlo, Abigail Kimmitt, Ellen Bikowski, Katherine R. Morris, Andrew Dolby

Virginia Journal of Science

Free-living birds are subjected to both external and internal stresses which can affect their health, activity, and reproductive success. To study stress in free living birds, they must be captured in nets and handled by the researcher to take blood samples for commonly used measures of stress, an activity which itself can induce stress and confound results. This study compares the effects of handling time on three different measures of stress: levels of the stress hormone corticosterone (CORT), levels of Heat Shock Protein 60 (HSP 60) and the ratio of heterophils to lymphocytes (H/L ratio) in tufted titmouse (Baeolophus bicolor …

Survey Of The Ectoparasites Of The Invasive Small Indian Mongoose (Herpestes Auropunctatus [Carnivora: Herpestidae]) On St. John, U.S. Virgin Islands, Kelsey L. Townsend, Karen E. Powers

Virginia Journal of Science

In March 2012, live trapping surveys were conducted for invasive small Indian mongoose (Herpestes auropunctatus) on St. John, U.S. Virgin Islands. Forty mongoose were sampled (31%, 9&) for ectoparasites, and cat fleas (Ctenocephalides felis) were discovered on 17 individuals. There was no difference in the number of ectoparasites per mongoose across age classifications (r = 0.109, P = 0.579). However, males had more cat fleas than females, even when mass was taken into account (males are generally heavier). Future behavioral studies may explain these sex differences. Although management suggestions from this research are limited, these …

Announcement: Vas Symposium Of State Of Virginia's Environment

Virginia Journal of Science

Announcement of and speakers scheduled for the Virginia Academy of Science Symposium on State of Virginia’s Environment Thursday, May 21, 2015 at James Madison University.

Current Status And Long-Term Trends In Water Quality And Living Resources In The Virginia Tributaries And Chesapeake Bay Mainstem From 1985 Through 2013, Daniel M. Dauer, Todd A. Egerton, John R. Donat, Michael F. Lane, Suzanne C. Doughten, Cindy Johnson, Monika Arora

Status and Trends for Virginia Chesapeake Bay

The period prior to the implementation of the Chesapeake Bay Monitoring Program was characterized by a marked decline in the water quality of the Chesapeake Bay. The disappearance of submerged aquatic vegetation in certain regions of the Bay, declines in the abundance of some commercially and recreationally important species, increases in the incidence of low dissolved oxygen events, changes in the Bay's food web, and other ecological problems have been related to the deteriorating water quality (e.g. USEPA, 1982,1983;Officer et al.,1984; Orth and Moore, 1984). The results of concentrated research efforts in the late 1970s and early 1980s stimulated the …

The Transfenestrational Imaginary: Periodizing Vineland’S Sixties, Johanna Isaacson

Reconstruction: Studies in Contemporary Culture

"The Transfenestrational Imaginary: Periodizing Vineland's Sixties" argues that the representational strategy in Vineland has much in common with Fredric Jameson's sixties periodization strategy, and offers a sustained analogy between narrative strategy and historiography. I suggest that Vineland is most productively seen as a continuation of the anti-literary genres of the sixties underground press and manifesto forms, genres that were necessarily temporary and politicized, and became opaque when separated from the context of active political social movements. The paper focuses on two key figures in the novel, Frenesi Gates and Zoyd Wheeler, and argues that the two are associated with …

Covington Is The Non-Place For Me: Walker Percy’S Topophilia In The Deserts Of Theory And Consumption, Chris Margrave

Reconstruction: Studies in Contemporary Culture

[First paragraph]

In a short, seemingly one-off essay, "Why I Live Where I Live," Walker Percy writes that particular cities can either aid or restrict a writer's ability to make sense of one's existence in the tumultuous twentieth century. For Percy, the ghosts of the past can inundate a place. He advised writers, especially Southern ones, to "avoid the horrors of total placement." In citing Charleston, South Carolina, and Mobile, Alabama, as places where a Southern writer's family has lived for 200 years, Percy remarks that such cities are prone to be haunted places where "ancestors perch on your shoulder" …

Review Of Eat It: Sex, Food And Women's Writing, Edited By Nicole Baute And Brianna Goldberg, Marc Ouellette

Reconstruction: Studies in Contemporary Culture

[First paragraph]

Simply put, Eat It: Sex, Food and Women's Writing surpasses its rather immodest claims. This is no mean feat, for the editors allow that they have collected short stories, non-fiction shorts and poetry that, as the back claims offers, hinge "on the carnal." More than that, the gathered works purportedly address the ways in which experiencing food entails nothing short of "power, biology, social obligation, experimentation, nourishment, pain and pleasure." The authors treat the topics, ranging from the politics of potatoes to tricks for field dressing deer, with a blend of seriousness and humour befitting the material. What …

Enhanced Breast Cancer Therapy With Nspefs And Low Concentrations Of Gemcitabine, Shan Wu, Jinsong Guo, Wendong Wei, Jue Zhang, Jing Fang, Stephen J. Beebe

Bioelectrics Publications

Chemotherapy either before or after surgery is a common breast cancer treatment. Long-term, high dose treatments with chemotherapeutic drugs often result in undesirable side effects, frequent recurrences and resistances to therapy. The anti-cancer drug, gemcitabine (GEM) was used in combination with pulse power technology with nanosecond pulsed electric fields (nsPEFs) for treatment of human breast cancer cells in vitro. Two strategies include sensitizing mammary tumor cells with GEM before nsPEF treatment or sensitizing cells with nsPEFs before GEM treatment.Breast cancer cell lines MCF-7 and MDA-MB-231 were treated with 250 65 ns-duration pulses and electric fields of 15, 20 or 25 …

Engineering Design: A Cognitive Process Approach, Greg Joseph Strimel

STEMPS Theses & Dissertations

The intent of this dissertation was to identify the cognitive processes used by advanced pre-engineering students to solve complex engineering design problems. Students in technology and engineering education classrooms are often taught to use an ideal engineering design process that has been generated mostly by educators and curriculum developers. However, the review of literature showed that it is unclear as to how advanced pre-engineering students cognitively navigate solving a complex and multifaceted problem from beginning to end. Additionally, it was unclear how a student thinks and acts throughout their design process and how this affects the viability of their solution. …

Predictors Patterns And Processes Of Extinction Risk In Porgies And Seabreams (Family: Sparidae), Mia Theresa B. Conteros

Biological Sciences Theses & Dissertations

A variety of human-induced changes are having profound impacts on the marine environment, and no area on the planet remains unaffected by the detrimental effects of our activities. These stressors can potentially lead to synergistic effects, causing accelerated biodiversity loss and diminished ecosystem functioning. Identification and understanding of the factors that drive species to heightened risk of extinction are important goals in conservation.

The Sparidae are commercially important and ecologically complex marine fishes; global extinction risk assessments using the IUCN Red List of Threatened Species methodology show that 9% (13 species) have increased vulnerability to population declines from intense fishing …

The Role Of Chemical Attractants In The Use Of Tick Traps For Life Stages Of Tick Species Ixodes Scapularis, Dermacentor Variabilis And Amblyomma Maculatum, Pamela C. Kelman

Biological Sciences Theses & Dissertations

Amblyomma maculatum, Ixodes scapularis and Dermacentor variabilis are three of the hard-bodied ticks found in the United States. This study explored three aspects of the appetence process of these tick species: attraction, desiccation survival, and locomotive activity. The first portion of this work was to improve one of the standard methods used for collecting ticks from the environment, the tick trap. To determine the attractants needed to capture all life stages of the three chosen species of ticks in the field using tick traps, a series of experiments were conducted using laboratory-reared larval, nymphal and adult A. maculatum, I. scapularis …

A Molecular Framework Phylogeny For Ptilotus (Amaranthaceae), Timothy A. Hammer

Biological Sciences Theses & Dissertations

Ptilotus (Amaranthaceae) is an Australian genus with over 100 species, most of which occur in arid Western Australia. Ptilotus has been a taxonomically difficult genus; despite rigorous morphological studies into the genus over many years, previous workers have found it difficult to delimit infrageneric groups due to inconsistent morphological variation. With the goal to establish a phylogenetic framework for the genus, 100 taxa were sampled, including 87 Ptilotus spp., and the ITS nrDNA and matK cpDNA were sequenced. The phylogeny was reconstructed using Bayesian, maximum likelihood and maximum parsimony analyses on separate and concatenated datasets. Morphological characters were assessed and …

Data Completion Methods For Improved Developmental Stage Annotation Of Drosophila Embryos In Images, Chitsanu Janyalikit

Electrical & Computer Engineering Theses & Dissertations

Drosophila melanogaster is a dominant model organism for studying the function of animal genes in initial stages of embryogenesis. Usually, images containing Drosophila gene expression patterns are captured at different developmental stages to study the interconnection of animal genes. To achieve most biologically meaningful results, gene expression images from a similar stage should be compared. Currently, biologists manually classify embryos in images into different stages, which is time intensive and infeasible for current massively produced gene expression images. Therefore, there is a need to develop an automatic system for the annotation.

Gene expression information in embryo images usually appears as …

Predation Thresholds In Marine Microbial Communities Applied To Environments With Low Prey Abundances, Bonnie Bailey

OES Theses and Dissertations

Prokaryotes (Bacteria and Archaea) comprise the largest component of biomass in the world's oceans. Their abundances are controlled by resource availability, viral infections and protist grazing. Many pico- and nano-eukaryotic predators grow almost as quickly as their prey, and greatly increase in numbers as soon as their prey do, leading in tum to depletion in prokaryotes. It is still unclear however, as to what extent microbial predators are able to feed in low prey environments, most prominently in the largest biome on Earth, the deep sea (below l 000 m depth). It has been hypothesized that in low prey environments, …

Protective Effects Of Social Support And Self-Esteem On Sexual Minority Young Adults' Mental Health, Sara Bock

Psychology Theses & Dissertations

Existing research has established that lesbian, gay and bisexual (LGB) youths experience higher rates of mental illness. However, fewer studies have examined what influences these disparate outcomes. Meyer's (2003) minority stress theory suggests that social factors, such as social support, and internal resources, such as self-esteem, are important potential moderators that may buffer the detrimental effects of stigma-related stress for sexual minority individuals. This study examined the potential protective effects peer support, parent support, school support, and self-esteem in adolescence in explaining mental health disparities between sexual minority and heterosexual young adults. Mental health outcomes included alcohol consumption, depressive symptoms, …

The Effects Of Primary And Secondary Assortative Mating For Alcohol Misuse On Relationship Satisfaction Alcohol Use And Alcohol Consequences, Michelle Katherine Holt Crewe

Psychology Theses & Dissertations

This study examined undergraduate, emerging-adult men and women between the ages of 18 and 30 and their dating partners. The AUDIT (Babor, Higgens-Biddle, Saunders, & Monteiro, 2001) was used to assess their own and their partners' reports of hazardous alcohol misuse. Four types of couples were identified: alcohol misusing participants with alcohol misusing partners (i.e., alcohol concordant couples), alcohol misusing female participants with a non-alcohol misusing partner, alcohol misusing male participants with an non-alcohol misusing partner and non-alcohol misusing women and men (i.e., non misuse concordant couples). Participants and their relationship partners were also assessed for their status as an …

Friends Of The Libraries Newsletter, September 2014, Fern Mcdougal (Editor)

Friends of the Libraries Newsletters

September 2014 Newsletter of the Friends of the Old Dominion University Libraries

State Of The University Address, 2014, John R. Broderick

State of the University Addresses

President John R. Broderick's 2014 State of the University Address and Faculty Welcome.

Biological Condition Of Money Pont Benthic Communities, Southern Branch Of The Elizabeth River (2010 And 2013), Daniel M. Dauer

Elizabeth River Reports

Executive Summary

The subtidal macrobenthic communities off Money Point in the Southern Branch of the Elizabeth River were quantitatively sampled in summer 2010 (Dauer 2011). The designated Money Point study area was part of a sediment contaminant remediation effort. The primary objectives of the present study were to: (1) characterize the biological health of the benthos of Money Point comparing pre-remediation (2010) and post-remediation (2013) conditions and (2) assess the effectiveness of the sediment contamination remediation efforts with respect to Money Point benthos. In this report the macrobenthic communities off Money Point were resampled in the summer of 2013 after …

Anammox Polishing In Mainstream Wastewater Treatment To Meet Stringent Ammonia And Total Nitrogen Limits, Rebecca Mary Holgate

Civil & Environmental Engineering Theses & Dissertations

As nitrogen discharge limits are becoming more stringent there is a need for new processes that are sustainable and cost effective. Since anaerobic ammonia oxidizing bacteria (anammox) were discovered in the mid 1990s, there has been considerable success implementing anammox in many wastewater treatment plants to treat internally generated nitrogen rich waste streams (e.g. centrate). Recently, there has also been discussion of implementing anammox in mainstream wastewater treatment to exploit the benefits of autotrophic nitrogen removal.

A two stage A/B pilot study was conducted that included a high-rate activated sludge (HRAS) process followed by a two-stage de-ammonification process incorporating nitrite-shunt …

Preparing Future Faculty Program (Pff) Annual Report, 2013-2014, Wie Yusuf

Career Pathways

It is the mission of the Preparing Future Faculty (PFF) Program at Old Dominion University (ODU) to introduce graduate students and post-doctoral fellows to the diverse roles, the responsibilities, and the rewards of an academic career. In doing so it focuses particularly on the teaching and service roles sometimes not included in doctoral training. Fundamental research skills, such as grant writing, publishing, and academic job searching, are also addressed.

The PFF program offers a ‘Preparing Future Faculty Certificate’ to graduate students who document completion of specific activities related to preparing for an academic career. Any ODU and NSU degree-seeking graduate …