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Synthesis Of Systematically Varied Nucleosides As A Logical Approach Toward Inhibitor Design For Nucleoside Transport Proteins, Lars P. C. Nielsen, Dr. Morris J. Robins Feb 2014

Synthesis Of Systematically Varied Nucleosides As A Logical Approach Toward Inhibitor Design For Nucleoside Transport Proteins, Lars P. C. Nielsen, Dr. Morris J. Robins

Journal of Undergraduate Research

Glucose transporter proteins constitute one class of transmembrane integral proteins that have received much attention in the current chemical literature. Many prominent groups have set out to explore their mechanisms, kinetics, and active sites. Studies have focussed on one of these in particular, Human Glucose Transporter I, the most common and efficient at mediating cellular glucose concentrations. Studies have also proven that certain nucleoside transporters exist, analogous to the sugar proteins, which regulate nucleoside and nucleotide concentrations in cells.

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Book Review: The Royal American Regiment: An Atlantic Microcosm, 1755-1772, Kevin Grimm Feb 2014

Book Review: The Royal American Regiment: An Atlantic Microcosm, 1755-1772, Kevin Grimm

Swiss American Historical Society Review

No abstract provided.

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Okuizumi Eizaburo At The University Of Maryland Libraries, 1974-1984, Frank Joseph Shulman Feb 2014

Okuizumi Eizaburo At The University Of Maryland Libraries, 1974-1984, Frank Joseph Shulman

Journal of East Asian Libraries

No abstract provided.

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Book Review: John Sutter: A Life On The North American Frontier, Evan C. Rothera Feb 2014

Book Review: John Sutter: A Life On The North American Frontier, Evan C. Rothera

Swiss American Historical Society Review

No abstract provided.

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The Federal Charter Of 1291 And The Founding Of The Swiss State, Albert Winkler Feb 2014

The Federal Charter Of 1291 And The Founding Of The Swiss State, Albert Winkler

Swiss American Historical Society Review

M ost countries have a national holiday to celebrate their identity or independence, often symbolized by some heroic event or defining moment. Switzerland's day of remembrance is August 1, which commemorates the creation of an alliance in 1291 when the states of Uri, Schwyz, and Nidwalden (part of Unterwalden) established a "perpetual league" by authorizing the "Federal Charter" or Bundesbrief. This pact was perhaps an early step toward the founding of the Swiss state, because it helped define the policies relating to sovereignty, internal affairs, mutual aid, and resistance to external threats. However, the document's nature, authenticity, and actual significance …

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Quantitative Genetics Of Response To Novelty And Other Stimuli By Infant Rhesus Macaques (Macaca Mulatta) Across Three Behavioral Assessments, G. L. Fawcett, A. M. Dettmer, D. Kay, M. Raveendran, James Dee Higley, N. D. Ryan, J. L. Cameron, J. Rogers Feb 2014

Quantitative Genetics Of Response To Novelty And Other Stimuli By Infant Rhesus Macaques (Macaca Mulatta) Across Three Behavioral Assessments, G. L. Fawcett, A. M. Dettmer, D. Kay, M. Raveendran, James Dee Higley, N. D. Ryan, J. L. Cameron, J. Rogers

Faculty Publications

Primate behavior is influenced by both heritable factors and environmental experience during development. Previous studies of rhesus macaques (Macaca mulatta) examined the effects of genetic variation on expressed behavior and related neurobiological traits (heritability and/or genetic association) using a variety of study designs. Most of these prior studies examined genetic effects on the behavior of adults or adolescent rhesus macaques, not in young macaques early in development. To assess environmental and additive genetic variation in behavioral reactivity and response to novelty among infants, we investigated a range of behavioral traits in a large number (N = 428) of pedigreed infants …

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High-Efficiency Thermodynamic Power Cycles For Concentrated Solar Power Systems, Marc T. Dunham, Brian Iverson Feb 2014

High-Efficiency Thermodynamic Power Cycles For Concentrated Solar Power Systems, Marc T. Dunham, Brian Iverson

Faculty Publications

This paper provides a review of high-efficiency thermodynamic cycles and their applicability to concentrating solar power systems, primarily focusing on high-efficiency single and combined cycles. Novel approaches to power generation proposed in the literature are also highlighted. The review is followed by analyses of promising candidates, including regenerated He-Brayton, regenerated CO2-Brayton, CO2 recompression Brayton, steam Rankine, and CO2-ORC combined cycle. Steam Rankine is shown to offer higher thermal efficiencies at temperatures up to about 600 ˚C but requires a change in materials for components above this temperature. Above this temperature, CO2 recompression Brayton cycles are shown to have very high …

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Preparation Of Green Fluorescent Protein Constructs For The Determination Of The Mechanism Of The Excision Of A Novel Intron, John Daniel Clinger, Dr. Daniel L. Simmons Jan 2014

Preparation Of Green Fluorescent Protein Constructs For The Determination Of The Mechanism Of The Excision Of A Novel Intron, John Daniel Clinger, Dr. Daniel L. Simmons

Journal of Undergraduate Research

Recent advances have greatly increased the utility of bioluminescence as a qualitative and quantitative tool in scientific research. The genes encoding fluorescent proteins in several organisms have been identified, cloned, modified, and inserted into several different vectors; thus allowing them to be used in a variety of diagnostic techniques. One such protein, isolated from aequorea victoria, is green fluorescent protein (GFP). Since GFP is encoded by a small gene, 720 base pairs, and fluoresces brightly when irradiated by ultraviolet light; it was seen as good candidate for the study of a novel pre-mRNA splicing mechanism.

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The Deification Of Man In Early Christianity, William Laduke, Dr. James L. Siebach Jan 2014

The Deification Of Man In Early Christianity, William Laduke, Dr. James L. Siebach

Journal of Undergraduate Research

Although I have not yet researched the subject as thoroughly as I had planned, I have discovered some interesting things about the deification of man in early Christianity. I began by searching the secondary literature and found that there was much more written on the subject than I had expected. The idea of deification was commonplace; for many, it was synonymous with salvation.

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Comparative Resistance Of Human Papilloma Virus To Inactivation By Selected Chemical Disinfectants, Elisabeth Tillman, Dr. Richard A. Robinson Jan 2014

Comparative Resistance Of Human Papilloma Virus To Inactivation By Selected Chemical Disinfectants, Elisabeth Tillman, Dr. Richard A. Robinson

Journal of Undergraduate Research

Cervical cancer is the fifth most common cancer in humans as well as the second most common cause of cancer death in women [3]. In developing countries, cervical cancer is actually the most common female disease, constituting 30% of female cancers [1]. In the United States, cervical cancer is diagnosed in approximately 15,000 women and is responsible for 4,600 deaths each year [2]. At least 90% of all cervical carcinomas are related to human papilloma virus (HPV) infection. The purpose of my study is to reduce the dangerous spread of HPV through effective disinfection.

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Determining Optical Constants With An Euv Polarimeter, Fabian Walter, Dr. R. Steven Turley Jan 2014

Determining Optical Constants With An Euv Polarimeter, Fabian Walter, Dr. R. Steven Turley

Journal of Undergraduate Research

Characterizing mirrors is of great importance when designing optical devices. In order to control the reflectivity, these mirrors are made of multilayer structures. The index of refraction n, which allows for the calculation of the reflectivity, depends on the wavelength of the light. In the XUV (extreme ultraviolet) regime, n is not well known and experiments to determine it have to be done under vacuum due to the absorption of XUV light by air. This complicates the performing of experiments with light of that wavelength.

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The Development Of An Active Noise Control System For A Small Axial Fan, Kent L. Gee, Dr. Scott D. Sommerfeldt Jan 2014

The Development Of An Active Noise Control System For A Small Axial Fan, Kent L. Gee, Dr. Scott D. Sommerfeldt

Journal of Undergraduate Research

Axial cooling fans used in computers, projectors, and printers often contribute significantly to background noise levels in both the workplace and classroom because of the distinct and often annoying tones they produce. These tones are principally caused by spatially unsteady flow through the fan, due to finger guards and other obstructions. Active noise control (ANC) lends itself as a viable approach to fan tonal noise reduction because of the low frequency nature of the noise, which limits the effectiveness and practicality of more traditional “passive” means of controlling noise. An ANC system cancels or attenuates unwanted noise by creating “antinoise” …

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Macrocycle-Substituted Resorcinarenes As Primary Functional Groups In Ion Chromatography, Arlo Mcginn, John D. Lamb Jan 2014

Macrocycle-Substituted Resorcinarenes As Primary Functional Groups In Ion Chromatography, Arlo Mcginn, John D. Lamb

Journal of Undergraduate Research

Ion chromatography is an instrumental technique known for its ability to determine and quantify mixtures of ions in solution. In ion chromatography, a solution containing different ions is passed through a column packed with a stationary phase containing active groups (chemical compounds that exhibit binding properties). These active groups show affinity for the various ions in solution. Chemical separations are achieved in ion chromatography by means of electrostatic interactions and coordinate covalent bond formation between the active groups in the stationary phase of the chromatography column and the ions present in the mobile phase or eluent. Strong interactions effectively slow …

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Four Poems, Four Voices: Fragmented Authorship In Fernando Pessoa, James Peter Rasmussen, Dr. Steven P. Sondrup Jan 2014

Four Poems, Four Voices: Fragmented Authorship In Fernando Pessoa, James Peter Rasmussen, Dr. Steven P. Sondrup

Journal of Undergraduate Research

The poetry of Fernando Pessoa contributes in a highly original way to a significant twentieth-century aesthetic development: the attempt to overthrow Romantic conceptions of authorship. Through the creation of his “heteronyms”—invented poets with a large degree of independence in style, form, imagery, and thought to whom he attributes his poetry—Pessoa’s poetry fragments into many distinct voices and thus challenges the notion of coherent authorial identity. Fernando Pessoa’s heteronymic structure itself is thus a quintessentially modern voice. The heteronyms challenge, as critic Darlene J. Sadlier writes, “the notion of coherent identity” (118).1 With the fragmentation of the poetic voice, the romantic …

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The Art Of Healing: An Inquiry Into And The Implications Of Practical Knowledge Grounded In Morality, Dennis Packard, Dr. Jared Inouye Jan 2014

The Art Of Healing: An Inquiry Into And The Implications Of Practical Knowledge Grounded In Morality, Dennis Packard, Dr. Jared Inouye

Journal of Undergraduate Research

I proposed to articulate the art of healing by examining the relationship between morality and practical knowledge. I proposed to examine this relationship by extensively interviewing and working with a local neurosurgeon. I hypothesized that his reputation as an excellent surgeon—a healer—was grounded in his moral way of being. One of the practical applications of my project was to show that if doctors are to be healers, then a doctor’s formal education usually isn’t sufficient and that measures to morally educate doctors ought to be taken. Another one of the practical applications was to show that the education doctors receive …

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The Reception Of Western Legal Reform In Bulgaria A Qualitative Study, Paul Edwards, Dr. Vanya Illieva Kalaidjieva Jan 2014

The Reception Of Western Legal Reform In Bulgaria A Qualitative Study, Paul Edwards, Dr. Vanya Illieva Kalaidjieva

Journal of Undergraduate Research

The research I did ultimately seeks to answer the question whether the door to the West is open for Bulgaria. Bulgaria is not a Western country, even though it is in Europe. In fact it has never been a Western country.

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Finding Poland In Stanis³Aw Wyspianski’S Wesele, Nicholas G. Newton, Walter Whipple Jan 2014

Finding Poland In Stanis³Aw Wyspianski’S Wesele, Nicholas G. Newton, Walter Whipple

Journal of Undergraduate Research

Towards the end of Stanis³aw Wyspianski’s Wesele (The Wedding), “the Poet”, speaking to the newly married bride describes Poland as something that you can only find in your heart. “A to Polska w³asnie”. The turn of the 19th century in Poland, when this wedding took place, was a very turbulent time in Poland’s history. In 1795, only four years after Poland wrote Europe’s first constitution, the final division of Poland was made by Russia, Prussia and Austria leaving nothing of the former Polish republic. Cracow, part of the Austrian province of Galicia, created a unique place where the ideas of …

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Selenium Alters Nf- B-Regulated Gene Expression In Human Prostate Cancer Cells, Aimee L. Taylor, Dr. Merrill J. Christensen Jan 2014

Selenium Alters Nf- B-Regulated Gene Expression In Human Prostate Cancer Cells, Aimee L. Taylor, Dr. Merrill J. Christensen

Journal of Undergraduate Research

The American Cancer Society estimates that prostate cancer will account for 30% of new cancers in men, totaling over 189,000 new cases, with 30,200 deaths in 2002 (1). Because of its high prevalence and long latency time prostate cancer is an ideal candidate for chemoprevention (2). Recent research suggests an inverse relationship between high dietary selenium (Se) intake or status and risk for prostate cancer. However, the mechanisms for Se’s protective effects against prostate cancer have not yet been determined. This project focused sharply on a single mechanism by which Se may alter gene expression and affect risk for prostate …

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Identifying Protein-Binding Sites In The Enhancer Region Of The Col11a2 Gene, Trevor Ellison, Dr. Laura C. Bridgewater Jan 2014

Identifying Protein-Binding Sites In The Enhancer Region Of The Col11a2 Gene, Trevor Ellison, Dr. Laura C. Bridgewater

Journal of Undergraduate Research

An enhancer is a DNA sequence that regulates a gene’s expression. It is the binding of proteins to a gene’s enhancer region (at its protein-binding sites) that regulates that gene’s expression in the cell. The Col11a2 gene is activated almost solely in chondrocytes (cartilage cells) (Lui et al., 1995) through this same type of protein binding. The Col11a2 gene is responsible, in part, for the formation of type XI collagen. Mutations in this gene have been shown to cause abnormalities ranging from skeletal deformities to hearing loss.

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French Utopian Socialists Coming To America: The Transformation Of Etienne Cabet’S Icarian Colony In Nauvoo, John Mccorquindale, Dr. Daryl Lee Jan 2014

French Utopian Socialists Coming To America: The Transformation Of Etienne Cabet’S Icarian Colony In Nauvoo, John Mccorquindale, Dr. Daryl Lee

Journal of Undergraduate Research

While many of the definitively American utopian groups have received a good deal of curious attention in the past century, the Icarian colonies are relatively unknown. Maybe it is because of their less accessible French background, or because their iconoclastic leader Etienne Cabet (who once garnered 95, 000 votes in the French presidential elections), died in total obscurity, that this mysterious community has disappeared almost entirely from the American consciousness and social tapestry. Whatever the reason, a unique cultural collision that provides insight into the effects of location on beliefs and practices is often overlooked, by both historians and sociologists …

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Defining Gender Differences In Suriname Through Language, Shaun Hunley, Dr. David Bowie Jan 2014

Defining Gender Differences In Suriname Through Language, Shaun Hunley, Dr. David Bowie

Journal of Undergraduate Research

For the people of Suriname, the word “Sranan” is more than just a word, it is a symbol of national pride and independence. “Sranan” is the native word for Suriname, a small country on the northeastern coast of South America. Throughout its remarkable history, Suriname has transformed into a nation rich in culture and values. Its unique society bears the scars of Dutch colonialism while absorbing facets of African, Indian, and Indonesian cultures.

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What I Meant To Say… My Experiment In Writing A First Novel, Olivia Debbie Birdsall, Dr. Louise Plummer Jan 2014

What I Meant To Say… My Experiment In Writing A First Novel, Olivia Debbie Birdsall, Dr. Louise Plummer

Journal of Undergraduate Research

I find it difficult to begin this report with a generalization about my topic of study, as most ORCA recipients do, because there is no generalization that seems appropriate for the subject of writing, or what my experience with it over the last year has been. Writing a novel, especially your first, is bound to be as unique an experience for each writer as the novels they produce. One great quandary simply doesn’t exist, nor does one great solution, nor one infallible technique or manner of writing. I did not set out to solve a problem that affects all of …

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Fa’Asamoa And Western Institutions: A Comparative Study Between American Samoa And (Western) Samoa, Henrietta P. Emerson, Dr. Ray C. Christensen Jan 2014

Fa’Asamoa And Western Institutions: A Comparative Study Between American Samoa And (Western) Samoa, Henrietta P. Emerson, Dr. Ray C. Christensen

Journal of Undergraduate Research

In most literature on the political systems of American Samoa and (Western) Samoa, the two countries are rarely grouped in the same study despite their shared cultural identity. An unincorporated territory of the United States, American Samoa tends to be classified with other U.S. territories which include Guam, the Northern Marianas, and the Virgin Islands (Cook 1995; Van Cleve 1993). Meanwhile, Samoa, an independent state since 1962, is more commonly compared to other independent Pacific island states (Lawson 1996; White and Linstrom 1997). While different colonial experiences clearly point out the reason for this separation, the inherent pervasiveness of Samoan …

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I Get Mad Just Thinking About It: Comparing Students’ Emotions And Beliefs Evoked By Anger In Mozambique And At Brigham Young University’S, Ryan Curtis, Dr. Matthew Spackman Jan 2014

I Get Mad Just Thinking About It: Comparing Students’ Emotions And Beliefs Evoked By Anger In Mozambique And At Brigham Young University’S, Ryan Curtis, Dr. Matthew Spackman

Journal of Undergraduate Research

An emotion consists of many things. Research in emotion has been a constant debate between those who believe that emotions are more biologically based, and those who believe emotions are more culturally based. Cross-cultural studies of emotion have been used from the beginning of this debate to assess the effect of culture on emotions. The purpose of this study was to help determine the role of culture in emotions. Specifically, it studies 1) the effect of culture on the appraisal of anger, and 2) the effect of culture on the experience of secondary emotions that come from remembering an anger …

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Time Vindicated: Looking Behind The Masque, Amy Elizabeth Jensen, Dr. Megan Sanborn Jones Jan 2014

Time Vindicated: Looking Behind The Masque, Amy Elizabeth Jensen, Dr. Megan Sanborn Jones

Journal of Undergraduate Research

The English courtly masque was an elaborate theatrical form of poetry, dance, music, and scenery that flourished under the reign of the Stuarts, James (1603–1625) and Charles I (1625– 1649). The masque’s spectacle, both highly theatrical and financially extravagant, reflected the magnificence of the king and the ideals of the court. Courtiers and royalty took part on stage as well as in the audience. The masques were also self-reflective; attention moved between the audience and the performers as each watched the other. As masque writer Ben Jonson wrote, masques were “the mirrors of man’s life.” Through the masque’s unique relationship …

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A Symbolic Study Of Van Eyck’S Annunciation, David Amott, Dr. Martha Peacock Jan 2014

A Symbolic Study Of Van Eyck’S Annunciation, David Amott, Dr. Martha Peacock

Journal of Undergraduate Research

The Northern Renaissance artist who best understood iconography’s potential in painting was Jan van Eyck (1390-1441), whose Annunciation (1434) is a masterpiece of Netherlandish art and one of the most important paintings of the Northern Renaissance. Integrated into this work is symbolism that refers to the Trinity, the Old and New Testament, and events leading up to the birth of Christ. Outside of the painting’s major symbolic cycle, however, are a number of other details that add further meaning to the scene. Among these are the rainbow colored wings of the Archangel Gabriel embellished with peacock feathers. These details are …

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Collisional Dynamic Elements Of The Pyrazine - N2o System:Middle And Low J States, La Moyne Tyler Mix Jan 2014

Collisional Dynamic Elements Of The Pyrazine - N2o System:Middle And Low J States, La Moyne Tyler Mix

Theses and Dissertations

Unimolecular reactions based on the Lindemann - Hinchelwood mechanism are important to understanding combustion and atmospheric processes. The main feature of this mechanism is the energy transfer probability distribution function, P(E',E). We have chosen to study P(E',E) through gas phase collisional dynamics probed with IR transient absorption spectroscopy. Post-collision absorption line widths for the pyrazine-N2O system are used to calculate lab frame translational temperatures. The translational temperatures reveal that collisions with large rotational energy transfer also transfer large amounts of translational energy. For J states >47 the relationship is linear indicating a constant impact parameter. Line widths for J=47 through …

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Some Reflections On The Revelation Of John In Mormon Thought: Past, Present, And Future, Grant Underwood Jan 2014

Some Reflections On The Revelation Of John In Mormon Thought: Past, Present, And Future, Grant Underwood

Studies in the Bible and Antiquity

No abstract provided.

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Mormon Studies And Method: The Rigors Of The Academic Study Of Religion And The Maturity Of Mormon Studies, Stephen C. Taysom Jan 2014

Mormon Studies And Method: The Rigors Of The Academic Study Of Religion And The Maturity Of Mormon Studies, Stephen C. Taysom

Mormon Studies Review

No abstract provided.

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Front Matter, Mormon Studies Review Jan 2014

Front Matter, Mormon Studies Review

Mormon Studies Review

No abstract provided.

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