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2020-10-04_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-10-03_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-10-03_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-10-02_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

2020-10-02_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Nadph-Quinone Oxidoreductase-1 Mediates Benzo-[A]-Pyrene-1,6-Quinone-Induced Cytotoxicity And Reactive Oxygen Species Production In Human Ea.Hy926 Endothelial Cells, Halley Shukla, Gabriella Gaje, Ashkon Koucheki, Ho Young Lee, Xiaolun Sun, Michael A. Trush, Hong Zhu, Y R. Li, Zhenquan Jia

Osteopathic Medicine, Jerry M. Wallace School of

Numerous studies conducted in the past have reported deaths in the human population due to cardiovascular diseases (CVD) on exposure to air particulate matter (APM). BP-1,6-quinone (BP-1,6-Q) is one of the significant components of APM. However, the mechanism(s) by which it can exert its toxicity in endothelial cells is not yet completely understood. NAD(P)H: quinone oxidoreductase-1 (NQO1) is expressed highly in myocardium and vasculature tissues of the heart and plays a vital role in maintaining vascular homeostasis. This study, demonstrated that BP-1,6-Q diminishes NQO1 enzyme activity in a dose-dependent manner in human EA.hy926 endothelial cells. The decrease in the NQO1 …

Handel’S Messiah: Stepping Stones Between Now And Then, Ariela Policastro, Emma Boze, Nathan Maras

2020 Festschrift: Georg Frideric Handel's "Messiah"

Original style and intent of period music can often be lost as modern performers attempt to recreate a centuries-old composition. In this paper Messiah by George Frideric Handel is discussed, offering insight in how to perform this piece while still honoring the full integrity of what the composer intended. Through an examination of past and current performances and opinions, it becomes clear that there are many distinct differences in ways this oratorio has been performed including stylistic choices, instrumentation, religious affiliation, and more.

Role Of Peroxiredoxins In Protecting Against Cardiovascular And Related Disorders, Y R. Li, Hong Zhu, Igor Danelisen

Osteopathic Medicine, Jerry M. Wallace School of

Peroxiredoxin (Prx) refers to a family of thiol-dependent peroxidases that decompose hydrogen peroxide, lipid hydroperoxides, as well as peroxynitrite, and protect against oxidative and inflammatory stress. There are six mammalian Prx isozymes (Prx1-6), classified as typical 2-Cys, atypical 2-Cys, or 1-Cys Prxs based on the mechanism and the number of cysteine residues involved during catalysis. In addition to their well-established peroxide-scavenging activity, some Prxs also participate in the regulation of various cell signaling pathways. Extensive animal studies employing primarily gene knockout models provide substantial evidence supporting a critical protective role of Prxs in various disease processes involving oxidative and inflammatory …

2020-10-01_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Csci 49380/79526: Fundamentals Of Reactive Programming- Assignment 1, Raffi Khatchadourian

Open Educational Resources

No abstract provided.

Csci 49380/79526: Fundamentals Of Reactive Programming- Syllabus, Raffi Khatchadourian

Open Educational Resources

No abstract provided.

Csci 49380/79526: Fundamentals Of Reactive Programming - Assignment 2, Raffi Khatchadourian

Open Educational Resources

No abstract provided.

Decorin Production By The Human Decidua: Role In Decidual Cell Maturation, C. D. Halari, P. Nandi, M. J. Jeyarajah, S. J. Renaud, P. K. Lala

Paediatrics Publications

Decidualization involves the proliferation and differentiation of fibroblast-like endometrial stromal cells into epithelioid-shaped and secretory ‘decidual’ cells in response to steroid hormones. Human decidual cells produce insulin-like growth factor-binding protein-1 and prolactin (PRL), two well-recognized markers of decidual cell maturation and a proteoglycan decorin (DCN). We reported that DCN restrains the human trophoblast renewal, migration, invasion and endovascular differentiation needed for uterine arterial remodeling during normal pregnancy. DCN overproduction by the decidua is associated with a hypo-invasive placenta and a serious pregnancy disorder, pre-eclampsia (PE). Furthermore, elevated maternal plasma DCN levels during the second trimester is a predictive biomarker of …

Density Functional Calculation Of The Molecular Properties Of The [Au20-C60-Au20]N? (N = 0, 1, 2, 3) Model Complexes, Jairo Castillo-Chará

College of Health, Science, and Technology

We have calculated molecular geometries, HOMO-LUMO gaps, Fermi levels and vibrational frequencies for the ?-linear, ?-bent and ?-coordinated [Au20-C60-Au20]n? (n = 0–3) complexes using the density functional B3LYP method and LANL2DZ basis sets. Our calculations showed that the ?-bent ?1(b)-[Au20-C60-Au20]3? complex is the global minimum structure with Au-C distances of 2.27 and 2.97 Å, respectively. The C60 calculated bouncing frequencies for the [Au20-C60-Au20]n? (n = 0–3) complexes appear at 18–60 cm?1 and compare well with the experimental value of 40 cm?1. The calculations of Mulliken charges indicate that the electrostatic interaction of the C60n? ions with the Au20 clusters plays …

Low Use Of Vacuum Extraction: Health Care Professionals’ Perspective In A University Hospital, Dar Es Salaam, Henrik Makokha-Sandell, Andrew Mgaya, Johanna Belachew, Helena Litorp, Hussein Kidanto, Birgitta Essén

Faculty of Health Sciences, East Africa

Background Use of vacuum extraction (VE) has been declining in low and middle income countries. At the highest referral hospital Tanzania, 54% of deliveries are performed by caesarean section (CS) and only 0.8% by VE. Use of VE has the potential to reduce CS rates and improve maternal and neonatal outcomes but causes for its low use is not fully explored.

Method During November and December of 2017 participatory observations, semi-structured in-depth interviews (n = 29) and focus group discussions (n = 2) were held with midwives, residents and specialists working at the highest referral hospital in Tanzania. Thematic analysis …

Letter To Editor Regarding: “Decrease In Neurosurgical Program Volume During Covid-19: Residency Programs Must Adapt”, Bukkambudhi V. Murlimanju, Adesh Shrivastava, Luis Rafael Moscote-Salazar, Md Moshiur Rahman

Open Access archive

No abstract provided.

Nephrology In Africa: Forgotten No More, Saraladevi Naicker, Vivekanand Jha

Open Access archive

No abstract provided.

Agreement And Repeatability Of Icare Ic100 Tonometer, Judy Jose, Ramesh S. Ve, H. Vijaya Pai, Sayantan Biswas

Open Access archive

Purpose: To find the agreement and repeatability of Icare ic100 tonometer. Methods: We included 150 subjects above the age of 18 years for this cross-sectional, multicenter study with intraocular pressure (IOP) ≥7 mmHg. After the initial ophthalmic examination, two masked examiners took five IOP measurements using three different instruments; Icare ic100, Icare TA01i, and Goldmann applanation tonometer (GAT) in only one eye of the participants. Comparison of agreement of IOP using different instruments was quantified with intraclass correlation coefficient (ICC) using the two-way random effects models of absolute agreement and Cronbach's alpha. The test-retest variability of the instruments was assessed …

Advances In Molecular Diagnosis Of Tuberculosis, Emily Maclean, Mikashmi Kohli, Stefan F. Weber, Anita Suresh

Open Access archive

Molecular tests for tuberculosis (TB) have the potential to help reach the three million people with TB who are undiagnosed or not reported each year and to improve the quality of care TB patients receive by providing accurate, quick results, including rapid drug-susceptibility testing. The World Health Organization (WHO) has recommended the use of molecular nucleic acid amplification tests (NAATs) tests for TB detection instead of smear microscopy, as they are able to detect TB more accurately, particularly in patients with paucibacillary disease and in people living with HIV. Importantly, some of these WHO-endorsed tests can detect mycobacterial gene mutations …

Hydroxychloroquine In Covid-19: Potential Mechanism Of Action Against Sars-Cov-2, Sairaj Satarker, Tejas Ahuja, Madhuparna Banerjee, Vignesh Balaji E

Open Access archive

Purpose of Review: The rapid spread of virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has turned out to be a global emergency. Symptoms of this viral infection, coronavirus disease 2019 (COVID-19), include mild infections of the upper respiratory tract, viral pneumonia, respiratory failure, multiple organ failure and death. Till date, no drugs have been discovered to treat COVID-19 patients, and therefore, a considerable amount of interest has been shown in repurposing the existing drugs. Recent Findings: Out of these drugs, chloroquine (CQ) and hydroxychloroquine (HCQ) have demonstrated positive results indicating a potential antiviral role against SARS-CoV-2. Its mechanism of …

Transient Analysis Of Systems Exhibiting Inverse Response And Their Control With Cstr As A Case Study, Rohan Lakhani, C. R. Srinivasan, Srividya Ra

Open Access archive

In this paper the phenomenon of inverse response from systems was investigated and its transient response thoroughly analyzed. Inverse response is shown by non-minimum phase systems and some minimum phase systems. Transient analysis of these systems is lacking in literature A case study was done for a non-linear, non-minimum phase CSTR (Continuous Stirred Tank Reactor), which was identified. Different control schemes were also implemented on other systems as well, which exibhit inverse responses, including model reference adaptive control. The finding shows that PID goes with the inverse response, is unable to suppress it and requires large control effort which can …

Impact Of Covid-19 On Academic Activities And Way Forward In Indian Optometry, Vidyut Rajhans, Usman Memon, Vidula Patil, Aditya Goyal

Open Access archive

Purpose: Academia is experiencing massive reforms globally amid lockdown in COVID-19 outbreak. This study is aimed to apprehend the enabling and impeding factors of these reforms, with a focus on optometry education. It brings together how the Indian optometry educational system has responded to COVID-19 disruptions with findings of the 2020 survey, in light of similar survey done in 2018. Methodology: A cross-sectional survey was designed to find changes in optometry training and adaptations of Indian optometry educators amid COVID 19 lockdown. In the last week of April 2020, on the observation that the majority of optometry institutions have switched …

A Circular Monopole Patch Antenna Loaded With Inverted L-Shaped Stub For Gps Application, G. A. Sowmya, Akshtha Kamath, Anala Keshava, Om Prakash Kumar

Open Access archive

This article introduces a planar monopole patch antenna for global positioning system (GPS) application. Our design has a circular patch with a stub of inverted L-shape which is used as the radiating portion and partial ground. Our proposed design of the stub allows the antenna to operate at a frequency of 1.5 GHz. The circular monopole is fed by an offset feeding to have an impedance match of 50 ohms. The compact antenna has been designed and simulated on RT Duroid 6006 material with relative permittivity (ɛr) of 6.15 and 0.0019 as the loss tangent. Our antenna has a dimension …

Genome Protection: Histone H4 And Beyond, Kundan Kumar, Romila Moirangthem, Rupinder Kaur

Open Access archive

Histone proteins regulate cellular factors’ accessibility to DNA, and histone dosage has previously been linked with DNA damage susceptibility and efficiency of DNA repair pathways. Surplus histones are known to impede the DNA repair process by interfering with the homologous recombination-mediated DNA repair in Saccharomyces cerevisiae. Here, we discuss the recent finding of association of methyl methanesulfonate (MMS) resistance with the reduced histone H4 gene dosage in the pathogenic yeast Candida glabrata. We have earlier shown that while the low histone H3 gene dosage led to MMS susceptibility, the lack of two H4-encoding ORFs, CgHHF1 and CgHHF2, led to resistance …

Salivary 8-Hydroxyguanosine Levels In Smokers And Non-Smokers With Chronic Periodontitis, Jothi Varghese, Vinutha Bhat, Yousef Rezaei Chianeh, V. Kamath

Open Access archive

This case-controlled clinical trial was performed on the salivary 8-hydroxyguanosine (8-OHdG) levels in smokers and non-smokers with chronic periodontitis after non-surgical periodontal therapy. Subjects (N = 40) with periodontitis (smokers and non-smokers) and with clinically healthy conditions (smokers and non-smokers) were assigned to this study. At baseline, clinical periodontal parameters (plaque index, gingival index, pocket probing depth and clinical attachment levels) were evaluated. Saliva samples were obtained pre- and post-treatment to quantify the 8-OHdG levels using Elisa technique. Subjects diagnosed with chronic periodontitis with smoking habit (CPs) and non-smokers (CPns) received scaling and root planing. In clinically healthy subjects with …

Experiencing The Ancient Indian Healthcare Science Of Ayurveda Through The Immersive Experiential Prism Of A Scholar From The Global North West Visiting An Ayurveda Centre In Coastal Karnataka, Basavaraj S. Hadapad, Anupama V. Nayak, Chaitanya Sanjay Mishra

Open Access archive

Ayurveda is an ancient age-old practice that for many centuries has developed to become the principle teaching of how to live a healthy lifestyle: “Ayurveda, the ancient traditional medicine of India, defines health as a state of complete physical, mental and spiritual well-being. The focus of Ayurveda is on a predictive, preventive and personalized medicine. This is obtained through low-cost personalized counseling about lifestyle measures (diet, activities, etc.), trying to involve the patient directly in the process of healing, increasing his self-awareness and good relationships with other people and nature”. Ayurveda approaches health from a holistic perspective. Its goal is …

Stress Related Temporomandibular Joint Disorders-A Comparative Study Between Preclinical And Clinical Undergraduate Students Of Dentistry, Munazza Sharfuddin, Ayshwarya Muralidharan, Premalatha Shetty, Aditya Nandan

Open Access archive

Objective: This cross-sectional study compared the proportion and severity of stress related TMD, gender predilection and influence of parafunctional habits in preclinical and clinical undergraduate students of dentistry. Method: The data was collected using Fonseca’s Anamnestic index and Zung’s Self-rating Anxiety Scale. The results were analyzed as proportions and percentage. Chi square test was used. A ‘p value’ of less than 0.05 was considered as significant. Results: Mild to moderate anxiety levels were seen in 6.4% females and 3.4% males.According to the FAI, 48.2% females and 67.8% males did not have TMD. Mild, moderate and severe TMD were seen in …

Knowledge, Attitude And Practice Of Undergraduate Students Regarding Toothbrush Contamination And Disinfection, Swapna Bettanapalya Venkatesh, Vignesh Kamath, Shibani Shetty, Smitha Sammith Shetty

Open Access archive

Background: Toothbrushes play a significant role in disease transmission as they act as a reservoir for microorganisms and aid in increasing the risk of infection in any individual. In recent years, the necessity of toothbrush disinfection has gained importance. Toothbrush disinfection should be recommended as a routine practice for all individuals. This study aimed to assess the knowledge, attitude, and practice of undergraduate students regarding toothbrush contamination and disinfection. Materials and methods: This study involved 446 undergraduate students between the age group of 18 to 23 years. A validated questionnaire was used to assess the knowledge, attitude, and practice of …

Evaluation Of Hepatoprotective Effect Of A Polyherbal Megakutki Against Paracetamol-Induced Hepatotoxicity, Asha Elizabeth Giri, Vanishree Rao, Sandeep Singhal, Karthik Gourishetti

Open Access archive

Background: Megakutki® (MK) is a polyherbal preparation of 11 standardized extracts that are individually proven for hepatoprotection scientifically. Aim: Study evaluated MK’s hepatoprotective potential against paracetamol (PCM) in in-vitro on Hep G2 cells using cell viability, cell cycle analysis and apoptotic studies and in in-vivo in Wistar rats using liver function tests, histological and DNA fragmentation study. Materials and Methods: In in-vitro studies, IC50 (50% inhibition in viability) values of silymarin, MK and PCM were found out by MTT assay. In-vitro hepatoprotection was found out by pretreating the cells with below-IC50 concentrations of MK and silymarin for 24h followed by …

A Treatment Protocol For Minimizing Duration And Complications Of Adenoviral Epidemic Keratoconjunctivitis, Chidanand Kulkarni, Kirthinath Ballal

Open Access archive

PURPOSE: The purpose of the study was to assess the treatment protocol of topical 2.5% Povidone-Iodine (PovI) and 0.1% fluorometholone (FluM) for Adenoviral Epidemic keratoconjunctivitis (EKC) in reducing the duration and severity of the disease as compared to conventional treatment. This was a retrospective case-control study. MATERIALS AND METHODS: Cases were defined as patients with EKC receiving the treatment protocol and conjunctival swab taken for polymerase chain reaction. Controls were defined as similar patients receiving conventional treatment protocol. Forty-one cases and 35 controls were identified for analysis. Cases were treated with a protocol using 2.5% povidone-iodine eye drops and 0.1% …