Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- The Texas Medical Center Library (25830)
- Thomas Jefferson University (14938)
- Chulalongkorn University (11393)
- Washington University School of Medicine (10583)
- Aga Khan University (9507)
-
- University of Kentucky (8643)
- TÜBİTAK (8080)
- Walden University (6121)
- Western Michigan University (5805)
- Virginia Commonwealth University (5389)
- University of Nebraska - Lincoln (5204)
- Edith Cowan University (5076)
- American Dental Association (4410)
- Western Kentucky University (4358)
- Lehigh Valley Health Network (4097)
- University of Texas Rio Grande Valley (4037)
- Nova Southeastern University (4005)
- Himmelfarb Health Sciences Library, The George Washington University (3652)
- Universitas Indonesia (3627)
- University of Nebraska Medical Center (3620)
- Old Dominion University (3548)
- University of Nevada, Las Vegas (3358)
- Marquette University (3249)
- University of South Carolina (3146)
- University of Alabama at Birmingham (3145)
- Children's Mercy Kansas City (3010)
- Wright State University (2936)
- HCA Healthcare (2908)
- Western University (2905)
- University of North Dakota (2886)
- Keyword
-
- Humans (25827)
- Female (11946)
- Male (10553)
- Animals (7822)
- COVID-19 (7422)
-
- Adult (6218)
- Middle Aged (5245)
- Mice (5167)
- ICTS (Institute of Clinical and Translational Sciences) (5165)
- Aged (4699)
- Child (3583)
- Adolescent (3122)
- United States (2932)
- Michigan (2883)
- Nursing (2620)
- Education (2580)
- Obesity (2502)
- Mental health (2430)
- Depression (2373)
- Public health (2307)
- Retrospective Studies (2275)
- English (2266)
- Pregnancy (2216)
- Cancer (2192)
- Thomas Jefferson University (2032)
- Children (2007)
- Treatment Outcome (1918)
- Young Adult (1840)
- Infant (1768)
- Occupational therapy (1694)
- Publication Year
-
- 2026 (15662)
- 2025 (24599)
- 2024 (27212)
- 2023 (27449)
- 2022 (23770)
-
- 2021 (21408)
- 2020 (20658)
- 2019 (16116)
- 2018 (15442)
- 2017 (14547)
- 2016 (12732)
- 2015 (11981)
- 2014 (9578)
- 2013 (7937)
- 2012 (7324)
- 2011 (6784)
- 2010 (5707)
- 2009 (4385)
- 2008 (3703)
- 2007 (3122)
- 2006 (2765)
- 2005 (2797)
- 2004 (2219)
- 2003 (1917)
- 2002 (1800)
- 2001 (1650)
- 2000 (1582)
- 1999 (1656)
- 1998 (1488)
- 1997 (1145)
- Publication
-
- Faculty, Staff and Student Publications (13671)
- Faculty, Staff and Students Publications (7831)
- 2020-Current year OA Pubs (7437)
- Walden Dissertations and Doctoral Studies (5875)
- Turkish Journal of Medical Sciences (4871)
-
- Theses and Dissertations (4195)
- Chulalongkorn Medical Journal (4154)
- Turkish Journal of Veterinary & Animal Sciences (3209)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (3086)
- International Journal of Exercise Science: Conference Proceedings (2674)
- The Thai Journal of Veterinary Medicine (2529)
- All ETDs from UAB (2525)
- Research outputs 2022 to 2026 (2400)
- Journal Articles (2396)
- Faculty Publications (2316)
- Electronic Theses and Dissertations (2239)
- Henry Ford Hospital Medical Journal (2151)
- Dissertations (1937)
- Loma Linda University Electronic Theses, Dissertations & Projects (1807)
- School of Medicine Publications (1705)
- Doctor of Nursing Practice Projects (1587)
- What's Happening (1535)
- Research outputs 2014 to 2021 (1525)
- Publications and Research (1511)
- Masters Theses (1503)
- Manuscripts, Articles, Book Chapters and Other Papers (1467)
- Dissertations and Theses (Open Access) (1411)
- Dartmouth Scholarship (1400)
- Reproductive Health (1317)
- Rehabilitation Practice and Science (1276)
- Publication Type
Articles 8941 - 8970 of 326449
Full-Text Articles in Entire DC Network
Integration Of The Science Of Team Science (Scits) With Applied Healthcare Frameworks: Interprofessional Education Through A University-Based Head Injury Clinic, Part Ii: Mixed Methods, Emily Balog, Susan Paparella, Natalia Noce, Stephanie Hubbell, Kelly Pena
Integration Of The Science Of Team Science (Scits) With Applied Healthcare Frameworks: Interprofessional Education Through A University-Based Head Injury Clinic, Part Ii: Mixed Methods, Emily Balog, Susan Paparella, Natalia Noce, Stephanie Hubbell, Kelly Pena
Translational Science in Occupation
Introduction: Effective healthcare delivery requires clinicians to function within high-performing, collaborative teams. To support this, interprofessional education (IPE) must provide opportunities that move beyond siloed training. This paper details the clinical application of a team science-informed educational intervention designed to prepare students for interprofessional practice (IPP) through a university-based head injury head injury clinic. Methods: The research team conducted a mixed methods case study with a convergent design to evaluate student outcomes. Eighteen graduate students from occupational therapy, physical therapy, and speech-language pathology participated in a 10-week clinic. Faculty delivered training in IPEC competencies, TeamSTEPPS® tools, and clinical processes before …
Editors' State Of The Journal: Making Academic Writing Accessible, Nicole Martino, Nancy E. Krusen, Stacy Smallfield
Editors' State Of The Journal: Making Academic Writing Accessible, Nicole Martino, Nancy E. Krusen, Stacy Smallfield
Translational Science in Occupation
No abstract provided.
Pedaling Through Discomfort: A Feasibility Study Of Faculty-Led Spin Classes And Their Impact On Student Engagement, Resilience, And Faculty-Student Relationships, Gabriela Baza, Elizabeth Hathaway
Pedaling Through Discomfort: A Feasibility Study Of Faculty-Led Spin Classes And Their Impact On Student Engagement, Resilience, And Faculty-Student Relationships, Gabriela Baza, Elizabeth Hathaway
Pursuit - The Journal of Undergraduate Research at The University of Tennessee
This study explored the feasibility and impact of faculty-led Spin classes on college students’ engagement, well-being, and connection with faculty. Offered twice weekly at 7 AM during Fall 2024, the classes aimed to promote physical activity, resilience, and faculty-student relationships. Twenty-six students attended at least one class, with a median attendance of 4.5 sessions. Post-semester surveys (88% response rate) assessed perceived exertion, interest, enjoyment, challenge, improvement, and instructor encouragement. Students reported high levels of engagement and positive challenge (RPE = 15.3; challenge = 6.4/7). Those attending 7 or more sessions reported significantly greater perceived improvement than those attending fewer sessions …
Conjoined Twins And Abortion Restrictions: Navigating 'Ban State' Challenges, A Case Report, Beau Morgan Nrp
Conjoined Twins And Abortion Restrictions: Navigating 'Ban State' Challenges, A Case Report, Beau Morgan Nrp
Pursuit - The Journal of Undergraduate Research at The University of Tennessee
This case report highlights an unusual scenario of a conjoined twin pregnancy resulting from intrauterine insemination in a state with restrictive abortion laws. Despite a diagnosis deemed not compatible with life, the patient faced legal barriers preventing termination within their home state. Forced to seek care out-of-state, the patient underwent a successful termination at ten weeks and three days after lengthy and expensive travel. This case stresses the complex challenges posed by restrictive abortion laws, impacting patient access to essential medical interventions. The case demonstrates the critical intersections between medical care, medical ethics, legal constraints, and patient outcomes in managing …
Investigating Corollaries Between Streptococcus Gallolyticus Subsp. Gallolyticus Virulence And Colorectal Cancer, Tyler G. Myers
Investigating Corollaries Between Streptococcus Gallolyticus Subsp. Gallolyticus Virulence And Colorectal Cancer, Tyler G. Myers
Pursuit - The Journal of Undergraduate Research at The University of Tennessee
Streptococcus gallolyticus subsp. gallolyticus (Sgg) is a gram-positive, non-beta-hemolytic bacterium that belongs to the Lancefield group D of streptococcal pathogens. For the past several decades, associations between Sgg bacteremia and colorectal cancer (CRC) have been apparent, with gastroenterologists routinely recommending colonoscopies for positive cases of Sgg in either blood or stool samples. However, current research has not wholly established whether Sgg acts as a causative agent of CRC or if pre-existing cancers make the lumen of the colon more hospitable to its colonization. Regardless, Sgg has been implicated in the modulation of host inflammatory pathways and subsequent remodeling …
Lsu Health New Orleans School Of Dentistry Welcomes Esperanza Academy For Give Kids A Smile Day
Lsu Health New Orleans School Of Dentistry Welcomes Esperanza Academy For Give Kids A Smile Day
New Orleans Dental Association News
LSU Health New Orleans School of Dentistry (LSUSD) reinforced its long standing commitment to community oral health by welcoming approximately 120 first, second, and third graders from Esperanza Academy for this year’s Give Kids a Smile Day—a national initiative dedicated to expanding access to dental care and oral health education for children
The article showcases the event services, activities, contributors, and fun photos full of costumes.
Sun Life U.S. And Dentaquest Announce 2025 Recipients Of The Health Access Hero Awards
Sun Life U.S. And Dentaquest Announce 2025 Recipients Of The Health Access Hero Awards
New Orleans Dental Association News
Sun Life and DentaQuest's Health Access Hero Awards recognize nonprofits and individual change-makers working to broaden access to health services and improve health outcomes for communities in need. One of the 2025 Health Access Hero Award winners is in NODA's own backyard: Dr. Douglas Cross, Dental Director at EXCELth Inc. Learn about both Dr. Cross and the awards in the article.
Noda News March 2026
New Orleans Dental Association News
New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.
2025 Noda Honor Dentist: James “Jimmy” Edward Burns, D.D.S., David J. Hildebrandt D.D.S.
2025 Noda Honor Dentist: James “Jimmy” Edward Burns, D.D.S., David J. Hildebrandt D.D.S.
New Orleans Dental Association News
The New Orleans Dental Association Honors & Awards committee is pleased to announce the recipient of the 2025 Honor Dentist: Dr. James "Jimmy" E. Burns. Dr. Burns is an LSU graduate and avid LSU football fan. He is a member of many professional dental groups and an advocate of organized dentistry. Within the article he credits several professional mentors and his father as role models.
The NODA Honor Dentist Award is presented annually “In Recognition of Outstanding Contributions And Exemplary Conduct in the Profession of Dentistry”.
Noda News February 2026
New Orleans Dental Association News
New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.
Perioperative Fluid Management In Cardiac Surgery: Contemporary Evidence And Clinical Controversies, Hussein Ali Hussein Al-Hchaimi, Hussein Alkhfaji, Majid Fakhir Al-Hamaidah, Mohammad Ali Hassan Jassim, Ammar Hoom Mahdi, Fatima Al-Sharwood, Sunder Etta
Perioperative Fluid Management In Cardiac Surgery: Contemporary Evidence And Clinical Controversies, Hussein Ali Hussein Al-Hchaimi, Hussein Alkhfaji, Majid Fakhir Al-Hamaidah, Mohammad Ali Hassan Jassim, Ammar Hoom Mahdi, Fatima Al-Sharwood, Sunder Etta
AUIQ Complementary Biological System
Perioperative fluid therapy is a cornerstone of anesthetic management in cardiac surgery, where both hypovolemia and hypervolemia are associated with increased morbidity, forming a ``U-shaped'' relationship with outcomes. This narrative review synthesizes evidence from peer-reviewed literature (2000–2024) identified via PubMed, Scopus, and the Cochrane Database, focusing on randomized trials, meta-analyses, and guidelines for adult cardiac surgery. A central debate persists regarding fluid choice. Current evidence supports the preferential use of balanced crystalloids over normal saline, as large-volume saline is linked to hyperchloremic acidosis and reduced renal perfusion. Colloids like albumin and hydroxyethyl starch (HES) offer efficient volume expansion but require …
Interdisciplinary Management Of Severe Pediatric Subglottic Stenosis: A Case Report Of Endoscopic Balloon Dilation Under Shared Airway Conditions, Margaretha Gunawan, Syahrial Marsintha Hutauruk, Fauziah Fardizza, Christopher Kapuangan, Mikhael Yosia
Interdisciplinary Management Of Severe Pediatric Subglottic Stenosis: A Case Report Of Endoscopic Balloon Dilation Under Shared Airway Conditions, Margaretha Gunawan, Syahrial Marsintha Hutauruk, Fauziah Fardizza, Christopher Kapuangan, Mikhael Yosia
AUIQ Complementary Biological System
Pediatric acquired subglottic stenosis is a high-risk airway condition that requires close coordination between anesthesiology and otorhinolaryngology teams, particularly during endoscopic interventions performed under shared-airway conditions. This report describes the interdisciplinary management and anesthetic–surgical coordination in a child with severe acquired subglottic stenosis undergoing endoscopic balloon dilation, highlighting key decision points and airway management strategies. A 2-year-old boy with a history of prolonged and repeated endotracheal intubations presented with persistent dyspnea and noisy breathing, consistent with fixed extrathoracic airway obstruction. The case was reviewed in a multidisciplinary pediatric difficult-airway meeting, and operative management consisted of endoscopic airway evaluation and balloon …
Factors Associated With Immediate Postnatal Care In Lao People’S Democratic Republic: An Analysis Of The 2017 Lao People’S Democratic Republic Multiple Indicator Cluster Survey, Tressa Quayle, Jinyoung Kim, Jennifer Pharr, Rebecca Benfield
Factors Associated With Immediate Postnatal Care In Lao People’S Democratic Republic: An Analysis Of The 2017 Lao People’S Democratic Republic Multiple Indicator Cluster Survey, Tressa Quayle, Jinyoung Kim, Jennifer Pharr, Rebecca Benfield
Nursing Faculty Research
Background: The World Health Organization recognizes that approximately half of all maternal deaths occur in the immediate postnatal period or 24 h after birth. Forty-seven percent of Lao women aged 15–49 who delivered a baby in the last two years received a postnatal health check in the frst two days after delivery. After leaving the presence of a provider, 98.5% of these women never received another postnatal check. The maternal mortality ratio (MMR) in Lao PDR was 126 deaths per 100,000 live births in 2020. Immediate postnatal care (PNC) is a crucial step to improving maternal mortality. The aim of …
Implementation Of Centering-Based Antenatal Group Care In Flanders (Belgium): Experiences Of Women And Health Care Providers; Modalities For Sustainable Integration Into The Health Care System, Bianca Eerens, Astrid Van Damme, Nathalie Leister, Florence Talrich, Christine Mccourt, Deborah Lynn Billings Phd, Marsha Orgill, Matty Crone, Marlies Rijnders, Katrien Beeckman
Implementation Of Centering-Based Antenatal Group Care In Flanders (Belgium): Experiences Of Women And Health Care Providers; Modalities For Sustainable Integration Into The Health Care System, Bianca Eerens, Astrid Van Damme, Nathalie Leister, Florence Talrich, Christine Mccourt, Deborah Lynn Billings Phd, Marsha Orgill, Matty Crone, Marlies Rijnders, Katrien Beeckman
Faculty Publications
In Belgium, antenatal care is characterized by one-to-one care; with limited integration of community-based approaches. Centering-Based Group Care (CBGC), derived from the CenteringPregnancy® model, offers an alternative by combining clinical follow-up, health education, and peer support in group sessions. This study focuses on the experiences of participants and facilitators with the implementation of CBGC in three Flemish cities (Aalst, Gent, Leuven) as part of the European Union GC_1000 project. We explored the experience regarding the implementation process along with factors influencing sustainable integration into the health care system.
Methods
A total of 193 women participated in 30 CBGC trajectories …
The Impact Of Foot Care Education Within The Unhoused Female Population: A Community-Based Nursing Intervention, Bertha Karina Coronel Barragan, Jessica Sandoval, Afia Margaret Darko, Alexandra Elizabeth Lucero, Gloria Yeyoung Kim, Anyanka T. Ziegler
The Impact Of Foot Care Education Within The Unhoused Female Population: A Community-Based Nursing Intervention, Bertha Karina Coronel Barragan, Jessica Sandoval, Afia Margaret Darko, Alexandra Elizabeth Lucero, Gloria Yeyoung Kim, Anyanka T. Ziegler
Nursing Leadership in Community Engagement Projects
The Impact of Foot Care Education Within the Unhoused Female Population: A Community-based Nursing Intervention
The unhoused population is a vulnerable community that faces many obstacles in accessing healthcare (Benadda et al., 2025). Many of these individuals face stigmas related to their economic and housing conditions. It is important for nurses to be able to identify risk factors that may increase the prevalence of health-related problems, including using public health models to implement disease prevention. When discussing this population, one crucial preventative measure includes foot care, which aids in the deterrence of infections and promotes overall health (Coates et al., …
Trust Before Treatment: Educating Nurses On Trauma-Informed Care For Sex Trade Survivors, Matthew George Ditchik, Monserrat Castaneda, Daniela Tirado Osorio, Emily Haynes, Dani Salazar Tuparan, Joie Ikuzwe Mburu
Trust Before Treatment: Educating Nurses On Trauma-Informed Care For Sex Trade Survivors, Matthew George Ditchik, Monserrat Castaneda, Daniela Tirado Osorio, Emily Haynes, Dani Salazar Tuparan, Joie Ikuzwe Mburu
Nursing Leadership in Community Engagement Projects
Trust Before Treatment: Educating Nurses on Trauma-Informed Care for Sex Trade Survivors
Survivors of the sex trade often seek healthcare during some of the most vulnerable times in their lives, yet many report experiences of judgment, dismissal, or re-traumatization within clinical settings. Trauma-informed care is an approach that recognizes the lasting impact trauma can have on a person’s physical and emotional well-being and calls healthcare professionals to adjust their practices to promote safety, trust, autonomy, and empowerment. Research shows that implementing trauma-informed care improves patient well-being, enhances staff collaboration, and reduces the risk of further harm (Huo et al., 2023). …
An Individualized Approach To Medication Adherence And Safety For A Community Recovering From Addiction, Neena Marcus, Paige Kessler, Alexa Nehren, Anna Matushevskiy, Tianna Thompson, Veniamin Drozhzhyn
An Individualized Approach To Medication Adherence And Safety For A Community Recovering From Addiction, Neena Marcus, Paige Kessler, Alexa Nehren, Anna Matushevskiy, Tianna Thompson, Veniamin Drozhzhyn
Nursing Leadership in Community Engagement Projects
An Individualized Approach to Medication Adherence and Safety for a Community Recovering from Addiction
Adherence to prescribed medications is essential for the effective treatment and prevention of medical conditions. A study conducted in British Columbia, Canada, estimated that 50% of patients worldwide do not take their medications as prescribed (Zeitouny et al., 2023). Further, having substance use disorder can increase this risk (Mehdinia et al., 2020). Research with patients who are affected by polypharmacy found that pillboxes can support medication adherence (FarzanehRad et al., 2024). With these statistics in mind, our nursing student team developed a leadership project around pillbox …
Optimizing Healthcare Utilization: Distinguishing Between Emergency And Urgent Care, Madilyn Calkins, Molly Dupar, Wintana Gherie, Marcin Janczak, Angela Lee, Lena Zhang
Optimizing Healthcare Utilization: Distinguishing Between Emergency And Urgent Care, Madilyn Calkins, Molly Dupar, Wintana Gherie, Marcin Janczak, Angela Lee, Lena Zhang
Nursing Leadership in Community Engagement Projects
Optimizing Healthcare Utilization: Distinguishing Between Emergency and Urgent Care
Over the past two months, our group of six nursing students worked with a local transitional housing program for families. Per the facility report, a large portion of the program’s current residents are immigrants and have had little to no exposure to the American healthcare system and their options for care. The issue we targeted for our project is the increased number of 911 calls and emergency room (ER) visits for non-emergent healthcare concerns by our target population. By creating education materials on self-triaging, ER vs. Urgent Care services, and how …
Pediatric Thyroid Disorders: What Pediatricians Need To Know About Diagnosis, Referral, And Surgical Care, Michael Smith, John Dahl
Pediatric Thyroid Disorders: What Pediatricians Need To Know About Diagnosis, Referral, And Surgical Care, Michael Smith, John Dahl
Pediatrics in Practice: A CME Podcast
Pediatric thyroid disorders can present subtly but have significant implications if missed. In this episode, Jake Dahl, MD, PhD, MBA, discusses how pediatric thyroid disease differs from adult presentations, when pediatricians should consider specialty referral, and how endocrinology and surgery work together to guide care. The conversation offers practical insights to help pediatricians recognize red flags, navigate referrals, and support families through diagnosis and treatment.
Click here to stream the podcast episode.
Defining A Multi-Omic, Ai-Enabled Stool Screening Paradigm For Colorectal Cancer: A Consensus Framework For Clinical Translation, Arturo Loaiza-Bonilla, Yan Leyfman, Viviana Cortiana, Rhys Crawford, Shivani Modi
Defining A Multi-Omic, Ai-Enabled Stool Screening Paradigm For Colorectal Cancer: A Consensus Framework For Clinical Translation, Arturo Loaiza-Bonilla, Yan Leyfman, Viviana Cortiana, Rhys Crawford, Shivani Modi
Einstein Health Papers
Colorectal cancer (CRC) develops through both conventional adenoma-carcinoma and serrated neoplasia pathways, yet noninvasive screening still under-detects the advanced precursor lesions that enable true cancer prevention. Stool-based screening reduces CRC mortality, but its preventive impact remains constrained by limited detection of advanced precancerous lesions (APLs), including advanced adenomas and sessile serrated lesions. Next-generation multitarget stool DNA assays (mt-sDNA; e.g., Cologuard Plus) have established high sensitivity for CRC and specificity approaching 94%, leaving improved APL detection as the principal opportunity for innovation. This review presents a consensus framework for a multi-omic stool screening paradigm that integrates host epigenetic markers (DNA methylation) …
Communication Challenges Experienced By Telephone Triage Registered Nurses Providing Assessment Of Health Symptoms, Stacy Huddleston
Communication Challenges Experienced By Telephone Triage Registered Nurses Providing Assessment Of Health Symptoms, Stacy Huddleston
Walden Dissertations and Doctoral Studies
Telephone triage nurses routinely assess symptoms and make clinical decisions without visual contact, which introduces complex communication challenges. Language differences, emotional distress, cultural misunderstandings, and the absence of visual cues may influence how symptoms are described, interpreted, and acted upon during telephone encounters. The purpose of this qualitative interpretive description study, guided by Peplau’s theory of interpersonal relations, was to explore how RNs experience and manage communication barriers in telephone triage practice. Six RNs with recent experience in telephone triage participated in semistructured interviews, and the data were analyzed using interpretive description and thematic analysis. Findings indicated that participants relied …
94th Annual Georgia Public Health Association Meeting And Conference Report, Angela H. Peden, Beverley Townsend, Patrina L. Bowles, Sarah L. Mosley
94th Annual Georgia Public Health Association Meeting And Conference Report, Angela H. Peden, Beverley Townsend, Patrina L. Bowles, Sarah L. Mosley
Journal of the Georgia Public Health Association
The 94th Annual Meeting and Conference of the Georgia Public Health Association (GPHA) was held in Jekyll Island, Georgia, at the Jekyll Island Convention Center, on May 1-3, 2024. The goal of the 2024 Georgia Public Health Association Annual Meeting and Conference was to assemble public health professionals, students, County Board of Health members, and stakeholders for networking and educational opportunities to support the mission and vision of GPHA.
The theme for the 2024 Georgia Public Health Association Annual Meeting and Conference was selected by the GPHA Executive Board during a meeting in the early fall of 2023: “Lighting the …
Ulk4 And Cdkn2a Polymorphisms Influence The Risk Of Developing Monoclonal Gammopathy Of Undetermined Significance, José Manuuel Sánchez-Maldonado, Angelica Macauda, Antonio José Cabrera-Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany Van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz-Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero-Fernández, Elena Cabezudo, Fernando Reyes-Zurita, Alyssa I. Clay-Gilmour, Et. Al.
Ulk4 And Cdkn2a Polymorphisms Influence The Risk Of Developing Monoclonal Gammopathy Of Undetermined Significance, José Manuuel Sánchez-Maldonado, Angelica Macauda, Antonio José Cabrera-Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany Van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz-Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero-Fernández, Elena Cabezudo, Fernando Reyes-Zurita, Alyssa I. Clay-Gilmour, Et. Al.
Faculty Publications
Monoclonal gammopathy of undetermined significance (MGUS) is a necessary precursor condition to multiple myeloma (MM). Given the role of autophagy in modulating MM risk, we investigated whether genetic variation in autophagy-related genes influences susceptibility to MGUS. We analyzed the association of 34,042 common autophagy-related single nucleotide polymorphisms (SNPs) with MGUS across six independent cohorts, five from Europe and one from North America, comprising 2317 MGUS cases and 282,358 controls. We also assessed their impact on immune parameters, including absolute counts of 91 blood-derived immune cell subsets and 103 circulating immunological proteins. Meta-analysis revealed a genome-wide significant association between the ULK4 …
Impact Of Medicaid Enrollment Timing On Tumor Stage At Diagnosis And Survival In Breast, Colorectal, And Lung Cancer, Gabriel A. Benavidez, Stella Coker Watson Self Ph.D., Ms, Anthony Alberg Ph.D., M.P.H., Janice Probst, Jan Marie Eberth
Impact Of Medicaid Enrollment Timing On Tumor Stage At Diagnosis And Survival In Breast, Colorectal, And Lung Cancer, Gabriel A. Benavidez, Stella Coker Watson Self Ph.D., Ms, Anthony Alberg Ph.D., M.P.H., Janice Probst, Jan Marie Eberth
Faculty Publications
Background: Medicaid-insured patients experience higher rates of late-stage cancer diagnosis and worse survival than non-Medicaid patients. The impact of Medicaid enrollment timing on cancer outcomes is less clear. This study examines the association between Medicaid enrollment and timing with tumor stage and cancer-specific survival for breast, colorectal, and lung cancers. Methods: We analyzed SEER-Medicaid linked data for 276,755 breast, 104,784 colorectal, and 101,058 lung cancer patients < 65 years of age. Patients were categorized as non-Medicaid enrollees, pre-diagnosis enrollees (≥12 months before), or post-diagnosis enrollees (≤12 months after). Multivariable logistic regression estimated odds ratios of late-stage diagnosis, and cause-specific Cox proportional hazards models were used to assess cancer-specific survival, adjusting for demographic and socioeconomic factors. Results: Compared to non-Medicaid enrollees, post-diagnosis enrollees had the highest odds of late-stage diagnosis (breast cancer: OR: 3.41; colorectal cancer: OR: 3.78; lung cancer: OR: 1.87). Pre-diagnosis enrollees also had increased odds, but the …
Brain-Engrafted Monocyte-Derived Macrophages From Blood And Skull-Bone Marrow Exhibit Distinct Properties, Siling Du, Feiya Ou, Antoine Drieu, Eric Z Xu, Yumeng Cheng, Steffen E Storck, Tornike Mamuladze, Jay Cao, Nora Abduljawad, Bishan Bhattarai, Justin Rustenhoven, Niall Mortimer, Simone Brioschi, Khai Nguyen, Patrick Fernandes Rodrigues, Igor Smirnov, Daniel Gibson, J Michael White, Wandy Beatty, David Denardo, Qingyun Li, Michael Meers, Claudia Z Han, Na Sun, Florent Ginhoux, Marina Cella, Marco Colonna, Jonathan Kipnis
Brain-Engrafted Monocyte-Derived Macrophages From Blood And Skull-Bone Marrow Exhibit Distinct Properties, Siling Du, Feiya Ou, Antoine Drieu, Eric Z Xu, Yumeng Cheng, Steffen E Storck, Tornike Mamuladze, Jay Cao, Nora Abduljawad, Bishan Bhattarai, Justin Rustenhoven, Niall Mortimer, Simone Brioschi, Khai Nguyen, Patrick Fernandes Rodrigues, Igor Smirnov, Daniel Gibson, J Michael White, Wandy Beatty, David Denardo, Qingyun Li, Michael Meers, Claudia Z Han, Na Sun, Florent Ginhoux, Marina Cella, Marco Colonna, Jonathan Kipnis
The Brown Foundation: Institute of Molecular Medicine
Microglia arise from yolk sac progenitors and are thought to persist throughout life with minimal input from adult hematopoiesis. However, whether brain-engrafted monocyte-derived macrophages (MDMs) exist at homeostasis and during turnover and how they function relative to yolk-sac-derived microglia (YSMs) remain unsettled. Here, we combine lineage tracing, pharmacological microglia depletion, and multi-omics profiling to define the ontogeny, identity, and function of brain parenchymal macrophages. Despite sharing the parenchymal milieu, MDMs display transcriptional and epigenetic landscapes distinct from YSMs. Fate-mapping reveals that brain-engrafted MDMs transiently express CD206, echoing a developmental stage of microglial precursors. MDM engraftment and polarization are modulated by …
Schistosome Esophageal Gland Factor Meg-82 Drives Host Cell Lysis And Interacts With Host Immune Proteins, Pallavi Yadav, Sabona B Simbassa, Ryan Sloan, Phillip A Newmark, Jayhun Lee
Schistosome Esophageal Gland Factor Meg-82 Drives Host Cell Lysis And Interacts With Host Immune Proteins, Pallavi Yadav, Sabona B Simbassa, Ryan Sloan, Phillip A Newmark, Jayhun Lee
Faculty, Staff and Student Publications
Schistosomes are blood flukes that ingest large amounts of host blood during their intra-mammalian stage. The ingested blood contains leukocytes that can be harmful, yet the parasites survive inside the host for decades, reflecting superb immune evasion mechanisms that remain poorly understood. Our previous work discovered that FoxA, a forkhead transcription factor, drives the production of the esophageal gland, an anterior digestive organ essential for degrading ingested leukocytes and for in vivo survival. However, a comprehensive molecular makeup of the esophageal gland remains unclear. Importantly, the esophageal gland factors responsible for degrading ingested leukocytes, their mechanisms of action, and how …
Perspectives On Choice Of Law Challenges In Multistate Precision Medicine Research, Laura M. Beskow, Catherine Hammack-Aviran, James W. Hazel, Leslie E. Wolf
Perspectives On Choice Of Law Challenges In Multistate Precision Medicine Research, Laura M. Beskow, Catherine Hammack-Aviran, James W. Hazel, Leslie E. Wolf
Law Faculty Scholarship
This empirical legal study investigates challenges related to determining applicable law in multistate precision medicine research. Through interviews with experts in law, research ethics, and human subjects protections, the authors examine how differences in state laws governing research, genetic privacy, and data protection may affect participant rights and research practices. Interviewees reported varying levels of awareness regarding state law variation and expressed differing views on its significance. The findings suggest that uncertainty surrounding applicable legal frameworks can complicate research design, informed consent processes, and institutional oversight. The study calls for further legal and policy analysis to address these challenges and …
Adolescent And Parent Dyad Perceptions On The Utility And Implementation Ability To Use Cellphone-Based Technology To Reduce Distracted Driving In Philadelphia, Pennsylvania, Usa, Kevin Rix, Rachel Solomon, Mallory Lacy, M Kit Delgado, Jeffrey P Ebert, Douglas J Wiebe, Catherine Claire Mcdonald
Adolescent And Parent Dyad Perceptions On The Utility And Implementation Ability To Use Cellphone-Based Technology To Reduce Distracted Driving In Philadelphia, Pennsylvania, Usa, Kevin Rix, Rachel Solomon, Mallory Lacy, M Kit Delgado, Jeffrey P Ebert, Douglas J Wiebe, Catherine Claire Mcdonald
Faculty, Staff and Student Publications
Introduction: Losing focus while driving, including cellphone-based distractions (phone calls, text messages, other apps), is a prominent problem for adolescent drivers. Internal cellphone-based technologies designed to reduce distractions are prominent, but little is known about how parents and their children feel about their ability to successfully reduce distracted driving. This study interviews parents and adolescents to understand the utility and what is needed for implementation of these technologies.
Methods: Twenty (20) adolescent-parent dyads participated in semistructured qualitative interviews. Participants reflected adolescent drivers and their parents who previously had been documented as ranging from 'very low' risk drivers to 'very high' …
Current State And Needs Of Clinical Laboratories In Latin America: A Cross-Country Assessment., Alejandro R Molinelli, Elizabeth L Palavecino, José C Jara-Aguirre, Kerry Cosby, Allison Targowski, Barbara M Goldsmith, Rosa Sierra-Amor, Juan D García, Alicia Algeciras-Schimnich, Eugenio H Zabaleta, Veronica I Luzzi, Jessica M Colón-Franco
Current State And Needs Of Clinical Laboratories In Latin America: A Cross-Country Assessment., Alejandro R Molinelli, Elizabeth L Palavecino, José C Jara-Aguirre, Kerry Cosby, Allison Targowski, Barbara M Goldsmith, Rosa Sierra-Amor, Juan D García, Alicia Algeciras-Schimnich, Eugenio H Zabaleta, Veronica I Luzzi, Jessica M Colón-Franco
Ambulatory and Primary Care Articles
The Association for Diagnostics & Laboratory Medicine (ADLM) aims to improve health by providing education to laboratory scientists worldwide. Different regions of the world face unique challenges shaped by their national and regional contexts. However, the needs of clinical laboratories worldwide remain largely understudied. To address this gap, we conducted a comprehensive needs assessment survey among laboratory professionals in the Latin American region. The survey was distributed to over 2708 individuals across Latin American countries and yielded 148 responses. Most respondents were from urban areas (74%) and worked in private hospital laboratories (45%), with microbiology (25%) and chemistry (23%) identified …
Rates And Predictors Of Intention To Get Preventive Screenings Among Individuals In Recovery From Substance Use Disorders, Afsha Hossain, Ban A. Majeed, Lia Pierson Bruner
Rates And Predictors Of Intention To Get Preventive Screenings Among Individuals In Recovery From Substance Use Disorders, Afsha Hossain, Ban A. Majeed, Lia Pierson Bruner
Journal of the Georgia Public Health Association
Background: Individuals with substance use disorders (SUDs) are at greater risk for chronic disease but often face barriers to access and uptake of preventive screenings, so the aim of this study was to identify rates and predictors for intention to get preventive screenings among residents at two recovery centers.
Methods: We used a cross-sectional survey (N=95, response rate 51%) to determine previous screening rates and the intention to get recommended preventive screenings among residents of two long-term recovery programs in Athens, GA, using bivariate analysis with chi-square to look for associations with intention.
Results: Prior use of preventive health services …