Digital Commons Network^™

The Importance Of Behavioral Interventions And Stimulant Medication Effects On Reducing Attention Deficit Hyperactivity Disorder, Elizabeth Alvarez

Graduate Research Papers

Overall, various avenues of research state that ADHD is a complex disorder that requires treatment by multiple modalities. Most research states that a combination of medication and behavior therapy is necessary to resolve the symptoms. It should be noted that the dose of stimulant medication prescribed to a child with ADHD should be adjusted based on the child's response to a behavioral intervention, as well as the combination of the behavioral and pharmacological treatments. Rapport et al. (1982), as well as others, have found that medication alone will not "cure" ADHD. But with multiple methods of treatment the symptoms will …

A School Psychologist's Role In Decreasing Eating Disorder Prevalence In School-Aged Children, Natalie Muth

Graduate Research Papers

Eating disorders have dramatically increased over the last 20 years, resulting in prevalence rates exceeding other high-incidence medical conditions treated in the educational setting. Chapter 2 presents a review of literature covering eating disorder identification, history, prevalence and epidemiological data. Theoretical perspectives, risk and protective factors, symptoms, and medical complications are also reviewed. Current assessment measures used for screening and diagnosing anorexia and bulimia is additionally presented along with a summary of school-based primary prevention programs. The second chapter concludes with a brief overview of eating disorder treatment.

A summary is presented in chapter 3 along with implications for school …

Polymerase Chain Reaction: An Emerging Tool For Research In Pharmacology, Rishi Sharma, Manjeet Singh, Ajay Sharma

Pharmacy Faculty Articles and Research

Polymerase chain reaction (PCR) is a technique that can amplify a specific DNA segment in vitro using two site specific primers that hybridise to opposite DNA strands. The method produces large amounts of specific DNA from a complex DNA template in a single enzymatic reaction within a matter of hours. Reaction mixture contains a double helix DNA, two target specific primers, dNTPs, a DNA polymerase and a Mg2+ containing buffer. PCR is carried out in three distinct steps i.e. denaturation step, annealing step and extension step, which are repeated many times. The efficiency of PCR is measured in terms of …

The End Of The Fertility Transition In The Developing World, John Bongaarts

Poverty, Gender, and Youth

Fertility declines are now underway in many developing countries, and the focus of the debate about future fertility trends is shifting from the early to the later phases of the transition. This study examines patterns and determinants of fertility in the developing world using UN estimates of the total fertility rates for 143 developing countries from 1950 to 2000. The main objective is to identify regularities in the past record that may provide clues to future trends. Three key findings emerge from this analysis. First, the pace of fertility decline decelerates as countries reach the later stages of the transition. …

What About Us? Bringing Infertility Into Reproductive Health Care, Okonofua Friday, Bishakha Datta

Poverty, Gender, and Youth

Infertility is a major reproductive health problem throughout much of the world. Despite the prevalence and seriousness of infertility, the population and reproductive health field has largely neglected this problem. National policies and international donor organizations have been one-sided in their focus on programs designed to prevent unwanted pregnancies. This issue of Quality/Calidad/Qualité, with clinic-based narratives and case reports from India and Nigeria, illustrates what is involved in trying to address the problem of infertility in developing countries. A possible framework for incorporating limited infertility care into a family planning or reproductive health program includes providing education and counseling, preliminary …

Cancer Dose-Response Modeling Of Low Dose Radiation Exposure, Gizelle Susette Baker

MUSC Theses and Dissertations

Many late effects from exposure to ionizing radiation, including cancers, have been described in the literature. The identification and quantification of radiation-induced health effects is an important and complex issue. Recommendations for radiation safety and protection from the International Commission on Radiological Protection are made using a linear no threshold risk model on epidemiological data. A major obstacle in this process is the limited availability of data to directly measure the health effects of radiation on human populations. One way to circumvent this problem IS to use experimental data from laboratory animals and extrapolate across species to man. The cancer …

A Culturally Appropriate Breast Health Educational Intervention Program For African American Women., Mary Ann Kelley

All ETDs from UAB

No abstract provided.

A Question Of Revenge: Munchausen Syndrome By Proxy And A Proposed Diminished Capacity Defense For Homicidal Mothers, E. Selene Steelman

Cardozo Journal of Equal Rights & Social Justice

The note argues that Munchausen Syndrome by Proxy (MSBP) should be legally recognized as a severe mental disorder, allowing defendants to use a diminished capacity defense in cases of accidental filicide. The author critiques the legal system's inconsistent treatment of MSBP, which often focuses on the physical harm to the child while neglecting the mother's mental state. By acknowledging MSBP as a psychiatric disorder, the law could achieve more nuanced outcomes that consider both the act and the defendant's mental condition, reducing stigma and promoting fairness in criminal liability assessments.

Plasmid-Mediated Expression Of Foreign Genes In Ehrlichia Canis, Langston Dolphus Hull

LSU Doctoral Dissertations

Ehrlichia canis is the etiologic agent of “tropical canine pancytopenia”, or canine ehrlichiosis. The impetus for this research was to overcome the lack of any reliable means of elucidating the genetic profiles of these illusive and historically difficult to manipulate organisms. The use of a broad-host range plasmid greatly facilitated the determination of an electro-transformation protocol. The transforming plasmid possesses a chloramphenicol antibiotic resistance gene marker (chloramphenicol acetyltransferase [CAT] gene), and a visual reporter gene marker, the Green Fluorescent Protein (GFP) gene. With primer sets designed to specifically amplify these two plasmid encoded gene markers, thus verifying the presence of …

Outlook Magazine, Summer 2002

Outlook Magazine

No abstract provided.

Health Professions Division Catalog Academic Year 2002-2003, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Coccidian Parasites (Apicomplexa: Eimeriidae) Of Select Rodents Of Western And Southwestern Arkansas And Northeastern Texas, Chris T. Mcallister, Joshua E. Kessler

Journal of the Arkansas Academy of Science

No abstract provided.

Parasites Of Four Endemic Plethodon From Arkansas And Oklahoma, Chris T. Mcallister, Charles R. Bursey, Stanley E. Trauth

Journal of the Arkansas Academy of Science

No abstract provided.

Molecular Investigation Of Genetic Variability Among Borrelia Infecting Ticks In Florida Using Base Exision Sequence Scanning, Larry W. Martin

All Volumes (2001-2008)

Lyme disease (LD), the most commonly reported arthropod-associated illness in the U.S., is a multi-system tick-borne illness caused by the spirochete Borrelia burgdorferi. In the eastern U.S. the agent is transmitted by the blacklegged tick, Ixodes scapuiaris, and primarily maintained in nature by rodent reservoirs. Although the majority of human cases has been concentrated in the northeastern U.S., hundreds have also been reported in southern states. Some of these cases represent exposures that occurred elsewhere in the country. However, many were from endemic exposures, from which numerous indigenous cases have been confirmed in the Southeast. Putative B. burgdorferi …

Biomarkers Of Bone Turnover In Vegetarians And Omnivores, Susan Kim Louie Lue

Loma Linda University Electronic Theses, Dissertations & Projects

A cross-sectional study on fasting serum and 24-hour urine samples were used to determine whether biochemical markers of bone turnover, resorption and formation, differed in a group of 50 healthy premenopausal Caucasian women eating vegan, lactoovovegetarian(LOV) and omnivorous diets.

The women, ages 20-42, had participated in a study of bone mineral density(BMD). The three groups were comparable in mean age, BMI, calorie intake, calories spent in exercise, kcal/kg body weight, protein/day, protein/kg body weight and urinary creatinine.

Biomarkers included those of bone resorption—pyridinoline, deoxypyridinoline, and N-telopeptides, and of bone turnover—serum and urinary osteocalcin(OC), skeletal alkaline phosphatase, and propeptide-type-I-carboxyterminal-procollagen(PICP). In all …

Prosocial Development In Early Adulthood: A Longitudinal Study, Nancy Eisenberg, Ivanna K. Guthrie, Amanda Cumberland, Bridget C. Murphy, Stephanie A. Shepard, Qing Zhou, Gustavo Carlo

Department of Psychology: Faculty Publications

Consistency of measures of a prosocial personality and prosocial moral judgment over time, and the interrelations among them, were examined. Participants’ and friends’ reports of prosocial characteristics were obtained at ages 21– 22, 23–24, and 25–26 years. In addition, participants’ prosocial judgment was assessed with interviews and with an objective measure of prosocial moral reasoning at several ages. Reports of prosocial behavior and empathy-related responding in childhood and observations of prosocial behavior in preschool also were obtained. There was interindividual consistency in prosocial dispositions, and prosocial dispositions in adulthood related to empathy/sympathy and prosocial behavior at much younger ages. Interview …

Predictors Of Young Women's Attitudes Toward Sexual Health Practices, Alison G. Dougall

Theses : Honours

The present study examined whether cognitive (beliefs), affective (emotions) and I or behavioural processes predicted young women's attitudes towards their sexual health practices. For pragmatic reasons, safer sex promotion has largely relied on the provision of factual information to promote behaviour change. Although the importance of emotional and behavioural influences has been indicated, these elements have not traditionally been included in sexual health interventions. In order to examine this issue, Zanna and Rempel's (1988) tripartite model of attitude formation was used. A convenience sample of female participants (N=98) aged 18 to 29 years was asked to rate their attitudes towards …

Evaluating A Medical Error Taxonomy, Juliana Brixey, Todd R. Johnson, Jiajie Zhang

Faculty, Staff and Student Publications

Healthcare has been slow in using human factors principles to reduce medical errors. The Center for Devices and Radiological Health (CDRH) recognizes that a lack of attention to human factors during product development may lead to errors that have the potential for patient injury, or even death. In response to the need for reducing medication errors, the National Coordinating Council for Medication Errors Reporting and Prevention (NCC MERP) released the NCC MERP taxonomy that provides a standard language for reporting medication errors. This project maps the NCC MERP taxonomy of medication error to MedWatch medical errors involving infusion pumps. Of …

Current Status Of Defensins And Their Role In Innate And Adaptive Immunity, Periathamby A. Raj, Andrew R. Dentino

School of Dentistry Faculty Research and Publications

Naturally occurring antimicrobial cationic polypeptides play a major role in innate and adaptive immunity. These polypeptides are found to be either linear and unstructured or structured through disulfide bonds. Among the structured antimicrobial polypeptides, defensins comprise a family of cysteine-rich cationic polypeptides that contribute significantly to host defense against the invasion of microorganisms in animals, humans, insects and plants. Their wide-spread occurrence in various tissues of these diverse organisms, and their importance in innate and adaptive immunity have led to their identification, isolation and characterization. A large volume of literature is available on defensins’ occurrence, structural characterization, gene expression and …

Role Of Bcl-2 Family Members In Caspase-Independent Apoptosis Due To Chlamydia Infection, Jean-Luc Perfettini, John C. Reed, Nicole Israel, Jean-Claude Martinou, Alice Dautry-Varsat, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Infection with an obligate intracellular bacterium, the Chlamydia trachomatis lymphogranuloma venereum (LGV/L2) strain or the guinea pig inclusion conjunctivitis serovar of Chlamydia psittaci, leads to apoptosis of host cells. The apoptosis is not affected by a broad-spectrum caspase inhibitor, and caspase-3 is not activated in infected cells, suggesting that apoptosis mediated by these two strains of Chlamydia is independent of known caspases. Overexpression of the proapoptotic Bcl-2 family member, Bax, was previously shown to induce caspase-independent apoptosis, and we find that Bax is activated and translocates from the cytosol to the mitochondria in C. psittaci-infected cells. C. psittaci-induced apoptosis is …

Cognitive And Somatic Item Response Pattern Of Orofacial Pain Patients Compared To Fibromyalgia Patients And A Non-Pain Control Group, Morten Hadsel

University of Kentucky Master's Theses

Previous work has suggested that chronic pain patients report psychological distress through higher endorsement of somatic rather than cognitive signs of anxiety and depression. The present study compared female Non-Pain (11=52), Orofacial Pain (n=3 17) and Fibromyalgia (n=50) groups. on SCL-90-R Somatization, Anxiety and Depression raw scores and cognitive-somatic symptom patterning of the Anxiety and Depression scales. Comparisons were also made amongst orofacial pain diagnostic subgroups and subgroups based on Multidimensional Pain Inventory (MPI) classification groups. The Somatization. Anxiety and Depression scores were higher in the OroFacial Pain and Fibromyalgia than Non-Pain group and higher in the Dysfunctional than Adaptive …

Small Glutamine-Rich Protein/Viral Protein U–Binding Protein Is A Novel Cochaperone That Affects Heat Shock Protein 70 Activity, Peter C. Angeletti, Doriann Walker, Antonito T. Panganiban

Nebraska Center for Virology: Faculty Publications

Molecular chaperone complexes containing heat shock protein (Hsp) 70 and Hsp90 are regulated by cochaperones, including a subclass of regulators, such as Hsp70 interacting protein (Hip), C-terminus of Hsp70 interacting protein (CHIP), and Hsp70-Hsp90 organizing factor (Hop), that contain tetratricopeptide repeats (TPRs), where Hsp70 refers to Hsp70 and its nearly identical constitutive counterpart, Hsc70, together. These proteins interact with the Hsp70 to regulate adenosine triphosphatase (ATPase) and folding activities or to generate the chaperone complex. Here we provide evidence that small glutamine-rich protein/viral protein U–binding protein (SGT/UBP) is a cochaperone that negatively regulates Hsp70. By “Far-Western” and pull-down assays, SGT/UBP …

Influence Of Protein Tyrosine Kinases On Cell Volume Change-Induced Taurine Release, Herminia Pasantes-Morales, Rodrigo Franco

School of Veterinary and Biomedical Sciences: Faculty Publications

Taurine efflux occurs in association with cell swelling in both hyposmotic and isosmotic conditions and during cell shrinkage in apoptotic death. Release occurs through a leak pathway, is largely Ca²⁺-independent and is sensitive to Cl^– channel blockers. Taurine efflux elicited by hyposmolarity is reduced or suppressed by tyrosine kinase blockers and increased by tyrosine phosphatase inhibitors. The specific kinases involved are still unknown and may be different in the various cell types. Non-receptor and scr-related protein kinases have been identified in some cells as elements that directly phosphorylate the taurine efflux pathway. Possible tyrosine kinase targets are …

Methods And Compositions For Protection Against Bovine Viral Diseases, Subramaniam Srikumaran

School of Veterinary and Biomedical Sciences: Faculty Publications

The present invention relates to methods and compositions for eliciting an immune response against bovine viral epitopes. The methods comprise combining at least one heat shock protein with at least one bovine viral epitope to form a purified epitope/heat shock protein complex and administration of an immune system stimulating amount of the purified epitope/heat shock protein complex. The compositions comprise, a purified epitope/heat shock protein complex comprising at least one bovine viral epitope complexed with at least one heat shock protein, and a pharmaceutically acceptable carrier, diluent or excipient.

Effect Of Zinc On The Treatment Of Plasmodium Falciparum Malaria In Children: A Randomized Controlled Trial, F. Sempertegui, B. Estrella, F.R. Toapanta, D.S. Torres, D.E. Calahorrano, K. Yeboah-Antwi, E. Addo-Yobo, P. Arthur, S. Newton, Zul Premji, M. Hubert, C.S. Makwaya, F. Ssengooba, J. Konde-Lule, E. Mukisa, D.H. Hamer, W. Macleod, C. Duggan, W. Fawzi, J. Simon, V. Mwanakasale, M. Mulenga, T. Sukwa, J. Tshiula

Pathology, East Africa

Background: Zinc supplementation in young children has been associated with reductions in the incidence and severity of diarrheal diseases, acute respiratory infections, and malaria.

Objective: The objective was to evaluate the potential role of zinc as an adjunct in the treatment of acute, uncomplicated falciparum malaria; a multicenter, double-blind, randomized placebo-controlled clinical trial was undertaken.

Design: Children (n = 1087) aged 6 mo to 5 y were enrolled at sites in Ecuador, Ghana, Tanzania, Uganda, and Zambia. Children with fever and ≥ 2000 asexual forms of Plasmodium falciparum/μL in a thick blood smear received chloroquine and were randomly assigned to …

Detection Of Giardia Duodenalis Antigen In Coprolites Using A Commercially Available Enzyme-Linked Immunosorbent Assay, Marcelo Luiz Carvalho Gonçalves, Adauto Araújo, Rosemere Duarte, Joaquim Pereira Da Silva, Karl Reinhard, Françoise Bouchet, Luis Fernando Ferreira

Karl Reinhard Publications

The objective of this experiment was to assess the utility of a commercially available enzyme-linked immunosorbent assay (ELISA) kit for diagnosis of giardiasis in archaeological human remains. The kit, a monoclonal antibody assay, is used to detect the presence of Giardia-specific antigen 65 (GSA65) in human feces. We utilized the assay in ancient fecal material. The material included desiccated feces found in mummies or in archaeological sites, and sediments from latrines. A total of 83 specimens, previously examined microscopically for parasites, were examined. The ELISA detected 3 positive samples, dated to about 1200 AD, 1600 AD, and 1700 AD. …

Multidisciplinary Coprolite Analysis, Karl Reinhard, Dennis R. Danielson, Mark Daniels, Sérgio Augusto De Miranda Chaves

Karl Reinhard Publications

Coprolite analysis, as reviewed by Reinhard and Bryant (1992), contributes unique and detailed information regarding diet and parasitic disease. We present here an analysis of dietary components of coprolites from Bighorn Cave using macroscopic remains, pollen concentrations, and phytoliths. In addition, we analyzed Bighorn Cave coprolites for evidence of parasitic organisms, especially intestinal worms. Such analyses of coprolites have become important methods for reconstructing past dietary and medicinal practices. Pollen concentration and phytolith quantification techniques have recently been developed, but until this report no known attempt has been made to synthesize pollen, macroscopic, and phytolith data from a single coprolite …

Evidence For Infanticide In Bottlenose Dolphins Of The Western North Atlantic, Dale G. Dunn, Susan G. Barco, D. Ann Pabst, William A. Mclellan

Biological Sciences Faculty Publications

Nine bottlenose dolphin (Tursiops truncatus) calves that stranded in Virginia in 1996 and 1997 died of severe blunt-force trauma. Injuries were concentrated on the head and chest and multiple rib fractures, lung lacerations, and soft tissue contusions were prominent. Skeletal and/or soft tissue trauma occurred bilaterally in all of the calves. One had a bite wound across the left mandible that exhibited deep punctures consistent with the tooth placement in an adult bottlenose dolphin. The lesions were not compatible with predation, boat strike, fisheries interactions, rough-surf injury, or blast injury. However, they were similar to traumatic injuries described in stranded …

Nitric Oxide Ii: Therapeutic Uses And Clinical Applications, Ayşe Baysal

Turkish Journal of Medical Sciences

Nitric oxide is a biological mediator in human organisms which plays important roles in tissue and organ hemostasis. Recent advances in the therapeutic uses of inhaled nitric oxide in lung diseases and other pathologic states urges the efficient and appropriate use of nitric oxide in hospitals. This study is a literature search based on a keyword search and the abstracts in English in Medline. The therapeutic indications for inhaled nitric oxide and various clinical applications are summarized. Subsequently, adverse effects and toxicity for inhaled nitric oxide and contraindications for its use are discussed.

Development Of Dose Coefficients For Radionulides Produced In Spallation Neutron Sources: Annual Report, Phillip W. Patton, Mark Rudin

Transmutation Sciences Physics (TRP)

The University of Nevada, Las Vegas (UNLV) Transmutation Research Program has been tasked to support U.S. Department of Energy (DOE) efforts to assess the health risks associated with the operation of each of their accelerator-driven nuclear facilities for both NEPA and PSAR development. Quantifying the radiological risks to workers will have to be addressed during the design and siting of each of these facilities. U.S. Environmental Protection Agency (EPA) Federal Guidance Report No. 11 “Limiting Values of Intake and Air Concentration and Dose Conversion Factors for Inhalation, Submersion, and Ingestion”, developed two derived guides, Annual Limit on Intake (ALI) and …