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A French Canadian Family With Multiple Endocrine Neoplasia Type 2 Syndromes, Maurice B. Verdy, Marcel Cadotte, Walter Schurch, William C. Sturtridge, Jacques Cantin, Andrée M. Weber, André Lacroix, Cynthia Forster-Gibson

Henry Ford Hospital Medical Journal

No abstract provided.

Scintigraphy With 1-131 Mibg As An Aid To The Treatment Of Pheochromocytomas In Patients With The Multiple Endocrine Neoplasia Type 2 Syndromes, James C. Sisson, Brahm Shapiro, William H. Beierwaltes

Henry Ford Hospital Medical Journal

We reviewed the scintigraphic images made after injections of 1-131 metaiodobenzylguanidine (MIBG) or 1-123 MIBG in patients with multiple endocrine neoplasia (MEN) types 2A and 2B. The information we obtained was applied to three questions about the treatment of pheochromocytoma in patients affected with these syndromes. Our first question "When should adrenal gland(s) be removed?" was not directly answered. However, adrenalectomy generally should not be contemplated unless distinct abnormalities are present in the scintigraphic images. With experience it may be possible to approximate, from the stage of pheochromocytoma depicted by scintigraphy, how many years will elapse before symptoms or hypertension …

The Molecular Basis Of Polypeptide Hormone Production By Medullary Thyroid Cancer, C. J. M. Lips, P. H. Steenbergh, J. W. M. Höppener, J. Zandberg, H. S. Jansz

Henry Ford Hospital Medical Journal

Using recombinant DNA techniques, we analyzed the structure of human calcitonin (CT)-encoding DNA. The sequence of nucleotides derived from the messenger RNA (mRNA) predict the amino acid sequence of the entire human CT precursor protein. The complete CT gene could be isolated from a DNA library of the human genome. The CT precursor encoding sequences (exons) as well as the noncoding intervening sequences (introns) could be identified. Another sequence, called human calcitonin gene-related peptide (hCCRP), could be located near this CT-encoding DNA. A genomic fragment encoding hCCRP was used as a probe to detect and isolate the corresponding mRNA in …

Genetic Studies Of Multiple Endocrine Neoplasia Type 2 Syndromes: A Workshop Commentary, Nancy E. Simpson

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 1984-1985), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 1984-1985 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Founders Day/ Alumni Weekend
• Portrait of a President
• Highlights of Founders Day/Alumni Weekend
• Galen S. Young, Sr., DO
• Reunions and Reminiscences
• Sherman Leis, DO
• News from the OMCP
• News from the Alumni Office
• Faculty Notes
• Alumni News Briefs
• In Memoriam
• Coming Events

The Modified Index Of Severity Scale, Marion Gamundoy

Loma Linda University Electronic Theses, Dissertations & Projects

[No Abstract Included]

Correspondence, Jack R. Fecteau To William Bergen, D.O., 1984 November 28, Jack R. Fecteau

William F. Bergen, D.O. Collection

Letter from Jack R. Fecteau to William Bergen, D.O. regarding his experiences with the founding of the University of New England College of Osteopathic Medicine.

Correspondence, William K. Seldon To William Bergen, D.O., 1984 November 28, William K. Seldon

William F. Bergen, D.O. Collection

Letter from William K. Seldon to William Bergen, D.O. relating his experiences with the founding of the University of New England College of Osteopathic Medicine.

Correspondence, Howard L. Collier To William Bergen, D.O., 1984 November 27, Howard L. Collier

William F. Bergen, D.O. Collection

Letter from Howard L. Collier, Vice President of Finance at the Medical College of Ohio to William Bergen, D.O. describing his experience as a member of the AOA site visit team during the creation of the University of New England College of Osteopathic Medicine.

Correspondence, Between William Bergen, D.O. And M. Carmen Pettapiece, D.O., 1984 November 20, William Bergen D.O., M. Carmen Pettapiece D.O.

William F. Bergen, D.O. Collection

Letter to Carmen Pettapiece, D.O. from William Bergen, D.O. and his response regarding Dr. Bergen's attempt to gather stories of the founding of the New England College of Osteopathic Medicine.

A Comparison Of Selected Nutrition Factors Of Personal Care Residents With Nutrition For The Elderly Residents., Jill Kay Costin

Masters Theses & Specialist Projects

Persons in the Nutrition for the Elderly program in Barren River Area Development District in Kentucky and personal care residents at Lakeview Nursing Home, Morgantown, Kentucky, and Glasgow Rest Home, Glasgow, Kentucky participated I this study on a voluntary basis. The population consisted of an intact sample of sixty-eight persons: forty-six personal care residents (PC residents) and twenty-two Nutrition for the Elderly participants (NE participants). The Ne participants and Pc residents were compared to determine which received the best nutritional care. Selected parameters of nutritional assessment were compared for the two groups be means of a t test. The groups …

Genetics And Epidemiology Of Gallbladder Disease In New World Native Peoples, K M Weiss, R E Ferrell, C L Hanis, P N Styne

Faculty, Staff and Student Publications

Native peoples of the New World, including Amerindians and admixed Latin Americans such as Mexican-Americans, are highly susceptible to diseases of the gallbladder. These include cholesterol cholelithiasis (gallstones) and its complications, as well as cancer of the gallbladder. Although there is clearly some necessary dietary or other environmental risk factor involved, the pattern of disease prevalence is geographically associated with the distribution of genes of aboriginal Amerindian origin, and levels of risk generally correspond to the degree of Amerindian admixture. This pattern differs from that generally associated with Westernization, which suggests a gene-environment interaction, and that within an admixed population …

Correspondence: Nh Professional Matters: Portsmouth Hospital, John M. Shearman M.D.

William Kirmes, D.O. Collection

A letter from Dr. Shearman, Medical Director Portsmouth Rehabilitation Center, to Dr. Kirmes regarding a program, Treatment Strategies for Occupationally Related Injuries of the Lumbar Spine.

Vital Signs, Fall 1984, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1984), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1984 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• PCOM's Fifth President
• Mayor Proclaims Osteopathic Medicine Week
• Honoring Galen S. Young, DO
• Founders Day/Alumni Weekend Schedule
• Meet the Class of 1988
• Beth Mulvihill
• Living a Dream
• DO Wins Award
• Philadelphia Fair
• Fighter Doc Earns Medal
• News from the OMCP
• Faculty Notes
• Alumni News Briefs
• New Appointments
• In Memoriam
• Synapsis Ad

Developing An Integrated Natural Language Database For Gastrointestinal Disease, Peter J. Feczko, Laurens V. Ackerman, Robert D. Halpert, Stuart M. Simms

Henry Ford Hospital Medical Journal

Using a mainframe computer connected to the Henry Ford Hospital computer network, we developed a database for gastrointestinal disease which includes data from radiologic and endoscopic gastrointestinal examinations, along with corresponding pathologic diagnosis. Because of the large volume of procedures in our practice, we developed several unique features for our system. The user enters data by responding to a series of question-and-answer sets constructed by the clinical staff, who do not have experience in computer programming. Data is stored in a hierarchical format using natural language. Boolean logic is used to retrieve data so that different procedures can be correlated …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Cooperation Between A Radiology Computer Consortium And A Computer Manufacturer In The Development Of A Radiology Information System, Matthew W. Burke, Laurens V. Ackerman

Henry Ford Hospital Medical Journal

This article reports on the formation of a Radiology Information System Consortium (RISC) by 13 hospitals and medical centers in the United States, including Henry Ford Hospital in Detroit, and the cooperation between this consortium and a major manufacturer of computers and software. Digital Equipment Corporation (DEC), for the common goal of developing a state-of-the-art radiology information system.

Computer-Assisted Methods For Design Optimization Of Cardiac Bioprosthetic Valves, Mohamed S. Hamid, Hani N. Sabbah, Paul D. Stein

Henry Ford Hospital Medical Journal

Excessive mechanical stresses on valvular leaflets are considered an important factor in the degeneration of cardiac porcine bioprosthetic valves. This study describes a computer-assisted numerical model of a bioprosthetic valve which estimates the magnitude and distribution of leaflet stresses. The study also describes our initial attempts to determine the influence of stent height upon leaflet stresses. Whereas lowering stent heights has been suggested to improve hemodynamics in the bioprosthetic valve region, results indicate that an increase in leaflet stresses can accompany reductions of stent height.

Automating The Expertise Of The Neuropsychologist, Kenneth M. Adams, Gregory G. Brown

Henry Ford Hospital Medical Journal

No abstract provided.

Distributed Computing In A Hospital Environment, Steven R. Lund, Laurens V. Ackerman, James B. Martin

Henry Ford Hospital Medical Journal

Obtaining appropriate information in a timely fashion in medical practice has always been a burden for the practitioner. In a large hospital which undertakes major computer projects, this burden is intensified because information is not always available in a form directly usable by the physician or support personnel; it is now accumulated on diverse magnetic media where it is moved and processed as electronic pulses. This paper describes a solution which freely allows continued automation at different rates throughout a large hospital while expediting the movement of information where it is needed in a form understandable by the recipient.

Intracerebral Hemorrhage After Carotid Endarterectomy, José Biller, Andrew C. Hayes, Fred N. Littooy, William H. Baker

Henry Ford Hospital Medical Journal

Intracerebral hemorrhage (ICH) is a rare complication of carotid endarterectomy (CE). In our multicenter series of 1,180 CE (Baker-Littooy), three ICH occurred, of which two were fatal. One patient was receiving anticoagulants because ofa prosthetic aortic valve; another had rupture of a known ipsilateral intracranial aneurysm. Both occurred more than six weeks postoperatively. The third patient, who was hypertensive, had a nonfatal ipsilateral thalamic hemorrhage on the third postoperative day. Though these three patients represent only 0.25% of our series, they constitute 12% of our total strokes. ICH constitutes the largest percentage of nontechnically-related strokes and noncardiac deaths after CE.

A Microcomputer Database In A Clinical Environment, Dennis R. Ownby, Thomas A. Burnett

Henry Ford Hospital Medical Journal

No abstract provided.

Medical Applications Of Computers In The Hospital, Laurens V. Ackerman, Michael E. Somand

Henry Ford Hospital Medical Journal

No abstract provided.

Computer Applications In The Vascular Registry Of Henry Ford Hospital: Use Of A Simplified Access Method, Joseph P. Elliott Jr., Kunwar Kapoor, John G. Hageman, D. Emerick Szilagyi, Roger F. Smith, Michalene Mcpharlin

Henry Ford Hospital Medical Journal

The Vascular Registry of Henry Ford Hospital was initiated by one of the authors in 1957 to provide a consistent and accurate method of documenting and correlating the clinical results of the treatment of occlusive and aneurysmal arterial diseases. Data collection for each patient includes demographic information, treatment of clinical problems, and followup observations. Initially, the system consisted of keypunch cards and eventually magnetic tape processing. By 1980, it was necessary to further update the system because of the increase in patient volume, the need to minimize manual manipulations, and the demand for research data. The present system uses institutional …

Development Of A Nephrology And Hypertension Information System, Francis Dumler, Gerard Zasuwa, Nathan W. Levin

Henry Ford Hospital Medical Journal

This article describes our experience in the development and implementation of a computerized information system specifically designed for a Division of Nephrology and Hypertension. Specific issues related to planning and implementation are discussed, and potential pitfalls in setting up such a system are addressed. The combination of a mainframe and a miniframe as integral parts of the system and the development of peripheral support in specific applications using a personal microcomputer are also described. The important area of user/computer interface and of user motivation is discussed in the light of the experience acquired while implementing the current system.

Cardiac Papillary Fibroelastoma: A Source Of Coronary Artery Emboli And Myocardial Infarction, Gerald Fine, Shoba R. Pai

Henry Ford Hospital Medical Journal

Cardiac papillary fibroelastomas, although generally small and asymptomatic, have been suspected of being responsible for cerebral accidents, angina, and sudden death. The diagnosis of tumor embolization, considered in a number of cases, has been based on circumstantial evidence in all instances except for one case of sudden death due to embolism to the left anterior descending coronary artery. In all other cases, angina and sudden death have been related to a ball valve-type obstruction of a coronary ostium by tumor. The present case documents tumor embolism to peripheral right coronary arteries with associated, clinically silent myocardial changes.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

A Comparison Of Enamel Detachments After Debonding Between Unitek's "Dynalok" Bracket And A Foil-Mesh Bracket: A Scanning Electron Microscope Study, Robert E. Meister

Loma Linda University Electronic Theses, Dissertations & Projects

The intent of this paper was to: 1. Evaluate the mode of adhesive failure when debonding both flexible and rigid base orthodontic brackets. 2. Evaluate the bracket bases for enamel detachments. 3. Measure the enamel detachments.

After preforming shear test on flexible and rigid base orthodontic brackets mounted to extracted human teeth it was determined that failure occurred at the enamel/adhesive interface 30% of the time, at the bracket/adhesive interface 10% of the time and a combination of these 60% of the time for both groups.

Five brackets from each group were evaluated for enamel detachments using energy dispersive x-ray …