Digital Commons Network^™

Age-Related Changes Of Neurites In Meissner Corpuscles Of Diabetic, Vicky R. Ras

Loma Linda University Electronic Theses, Dissertations & Projects

This thesis is based on a qualitative and quantitative study of the neural component of Meissner corpuscles of diabetic and non-diabetic mice. Age-related changes were also documented in these mechanoreceptors. Corpuscles from forty-six diabetic mice and forty-six non-diabetic mice ranging from 2.5 to 17 months old were studied. Forepaw index digital pads were formalin-fixed and frozen-sectioned parallel to each digit and perpendicular to the skin. Serial sections were then silver-impregnated to allow light microscopic examination of the neurites in the corpuscles.

Neurites became more coarse, tortuous, branched, varicose, and thus more complex until middle age. Corpuscle size appeared greatest at …

New Mexico Location List Of Alumni And Former Housestaff, Unm Medical School Alumni Office

University of New Mexico School of Medicine Location Report

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 1984), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 1984 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• From the Chairman of the Board
• Lasers at PCOM
• The 93rd Commencement
• Commencement Photos
• The Honorary Degree Recipient
• The Commencement Dinner Dance
• Award Winners
• Families
• The Class of 1984 and Internship Hospitals
• News from the OMCP
• Interns/Residents Luncheon
• Faculty Notes
• Alumni News Briefs
• In Memoriam
• Synapsis Ad

The Effects Of Tri-O-Cresyl Phosphate On 2',3'-Cyclicnucleotide-3'-Phosphohydrolase Activity In Neural And Non-Neural Tissue Of The Rat, Mark K. Schlager

Chemistry & Biochemistry Theses & Dissertations

A total of 44 Long-Evans rats received 5.7 g/kg tri-O-cresyl phosphate (TOCP) orally every 3 days for 6 days. A second group of 13 rats received 4.6 g/kg orally every 3 days for 6 days. Animals were administered atropine sulfate (10 mg/kg) intraperitoneally every 6 hours or as needed to alleviate cholinergic symptoms. Ten control animals were given corn oil orally. Eight rats (18%) survived the 5.7 g/kg dose regimen and 5 rats (38%) survived the 4.6 g/kg dose regimen. Surviving rats were killed at 30-33 days post-dose. Signs of delayed neuropathy included ataxia and motor impairment.

The CNP activity …

Correspondence: Unecom: Aldrich To Kirmes 1984-6-6, Harrison F. Aldrich D.O.

William Kirmes, D.O. Collection

A letter from Dr. Harrison Aldrich, Chairman of the UNECOM Admissions Committee, to Dr. Kirmes updating him on the work of the Admissions Committee.

Influenza: Prevention And Therapy, William M. Valenti

Henry Ford Hospital Medical Journal

No abstract provided.

Immunology Of The Acquired Immunodeficiency Syndrome, Patrick W. Mclaughlin, Carl B. Lauter

Henry Ford Hospital Medical Journal

The Acquired Immunodeficiency Syndrome (AIDS) first recognized in 1981, has been extensively studied, and the most recent studies have demonstrated that its defects extend well beyond the apparent deficient cell-mediated immunity to include humoral immunity, autoimmunity, and abnormal immunoregulation. The recent discovery of a retrovirus, HTLV III, as a possible etiologic agent is discussed in relation to other viruses known to cause immunodeficiency. Simian AIDS, an animal model of virus-induced immunodeficiency, is also discussed. Recommendations are made regarding the interpretation and limitations of immune testing in AIDS, including a discussion of how apparently healthy homosexuals and groups at risk develop …

Medical Education In The United States: Some Current Problems And An Uncertain Future, Richard J. Reitemeier

Henry Ford Hospital Medical Journal

No abstract provided.

An Overview Of The Newer Antibiotics, Ramon Del Busto

Henry Ford Hospital Medical Journal

The introduction of a large number of new antibiotics has made selecting the one most appropriate for treatment a confusing task for the practicing physician. One problem is that the differences in pharmacokinetics, in vitro activity, and clinical indications between some of these agents may be relatively minor; this is especially true of the new cephalosporins. Another problem is that the generic names of the cephalosporins are so similar that it is impractical, even for the infectious diseases specialist, to be familiar with all of them. This review attempts to summarize the most important characteristics of these new antibiotics and …

Viral Hepatitis: Update On Prevention, Miriam J. Alter

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Infectious Diseases And The Persisting Microbial Challenge, Louis D. Saravolatz

Henry Ford Hospital Medical Journal

No abstract provided.

Prospects For The Medical Use Of Interferon In 1984, Bosko Postic, Julio C. Arroyo

Henry Ford Hospital Medical Journal

Interferon, a natural and wide spectrum antiviral polypeptide that was discovered in 1957, has been extensively described. In addition to its antiviral effect, interferon has been found to suppress tumor growth and modulate the immune response. Until 1980, interferon was primarily prepared for clinical trials in human leukocytes derived from the buffy coat of whole blood. A major breakthrough occurred in the late 1970s when human interferon was produced by DNA recombinant methods in such heterologous cells as bacteria (genetic engineering). Interferon is not commercially available in 1984, but it may, based on clinical trials in humans, become part of …

Congenital Seminal Vesicle Cyst: A Specific Diagnosis By Computed Tomography, Leo Drolshagen, Michael A. Sandler

Henry Ford Hospital Medical Journal

Computed tomography (CT) has been shown to be of great value in the assessment of the urinary tract. However, this modality has been primarily used in the evaluation of renal masses and the staging of urinary tract carcinomas. It may also be useful in less common abnormalities, such as mesonephric duct anomalies including congenital seminal vesicle cysts. These lesions are associated with renal agenesis and may produce urinary tract symptoms, or be discovered incidentally. We present a case of a congenital vesicle cyst associated with ipsilateral renal agenesis with characteristic CT findings allowing for a specific diagnosis.

A Case Of Ige Myeloma: Methodology And Review Of The Literature, Pat A. Allevato, Michael J. Deegan, Jau-Wen Chu, Mary B. Perry, Carolyn L. Barth

Henry Ford Hospital Medical Journal

A 56-year-old man presented with a one-year history of progressive weakness predominantly affecting his extremities and persistent low back pain. Ouchterlony immunodiffusion of the concentrated urine detected a marked increase in lambda light chains. A sternal bone marrow documented a diagnosis of multiple myeloma. Screening high resolution agarose gel electrophoresis revealed diffuse hypogammaglobulinemia and, retrospectively, an equivocal, faint band which migrated in the fast gamma region. By using a combination of Immunoelectrophoresis and immunofixation electrophoresis, this questionable band was determined to represent an IgE lambda monoclonal protein. Radioimmunoassay for IgE documented a serum concentration of 50.6 mg/dl. No intact IgE …

Rapidly Progressive Pancytopenia, Hepatomegaly, And Abnormal Lung Uptake Of Colloid In Systemic Lupus Erythematosus: Possible Saturation Of Reticuloendothelial System With Blood Elements, Tetsushi Sakurai, Kiyoshi Fukuda, Ichiro Kono, Teizo Kabashima, Kazuhide Yamane, Heihachiro Kashiwagi

Henry Ford Hospital Medical Journal

A patient with systemic lupus erythematosus developed severe abdominal pain and tender hepatomegaly associated with progressive pancytopenia and elevated serum levels of circulating immune complexes. Liver scintigram demonstrated extreme hepatomegaly with poor colloid uptake and splenomegaly with increased colloid uptake. An unusual accumulation of colloid in the lungs was also noted. Subsequent clinical and laboratory studies raised the possibility of saturation of the reticuloendothelial system in the liver by circulating immune complexes and blood cells, a condition demonstrated in experimental animals, but not hitherto well documented in the human immune complex disorder.

Tubal Lavage In The Management Of Ectopic Pregnancy, Samuel A. Motanya, William H. Pfeffer, Emile Sandelin, C. James Chuong

Henry Ford Hospital Medical Journal

No abstract provided.

Clinical Trials: I. Design And Ethical Issues, Barbara Tilley

Henry Ford Hospital Medical Journal

No abstract provided.

Editorial, Raymond C. Mellinger

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Temporomandibular Joint Relations Of Bone And Lateral Pterygoid Muscle : A Computerized Tomography Study, Duane K. Yamashiro

Loma Linda University Electronic Theses, Dissertations & Projects

This study utilized the imaging technique of computerized tomography (CT). Scans taken with a GE CT/N 8800 scanner of an adult cadaver and a 12-patient group were obtained through the Loma Linda University School of Dentistry, TMJ Department, and Loma Linda University Medical Center, Department of Neuroradiology.

The lateral scout image and a lateral cephalogram of the cadaver were compared using six angular measurements for facial type from Ricketts' Cephalometric Analysis. The six measurements, Maxillary Depth, Facial Depth, Mandibular Arc, Mandibular Plane, Lower Face Height and Facial Axis, were found to be similar. This allowed the investigator to rely exclusively …

Third Molar Eruption Prediction, Michael L. Jacobsen

Loma Linda University Electronic Theses, Dissertations & Projects

The diagnosis and treatment of third molars has often been cited as a special problem to the orthodontist. If the prognosis of third molars could be determined, orthodontic treatment could progress on a more positive basis.

This study was designed to provide a method of deciding whether developing third molars will erupt or become impacted.

Records from 130 orthodontically treated cases of Dr. Fredsall⁸ were studied. Several factors were evaluated and measured using the patients' cephalometric radiographs.

The actual fate of the third molars were recorded in the hope it could be used to predict what to expect from …

How Registered Nurses In Skilled Nursing Facilities Rate The Importance Of And The Frequency Engaged In Specific Nursing Behaviors Related To Their Role, Christine Anne Heine

Ellmer School of Nursing Theses & Dissertations

Registered nurses in skilled nursing facilities were surveyed using the Six-Dimension Scale of Nursing Performance to determine: (1) how they rated the importance of specific nursing behaviors related to their role, (2) how they rated the frequency engaged in the same specific nursing behaviors related to their role, and (3) if there was a relationship between how they rated the specific nursing behaviors for importance and frequency. There were five subgroups of nursing behaviors: (a) leadership, (b) nursing process, (c) teaching and collaboration, (d) interpersonal relations and communication, and (e) professional development. Registered nurses rated all of the behaviors as …

Inhibition Of Growth Of Toxoplasma Gondii In Cultured Fibroblasts By Human Recombinant Gamma Interferon., E. R. Pfefferkorn, Paul M. Guyre

Dartmouth Scholarship

The growth of Toxoplasma gondii in cultured human fibroblasts was inhibited by recombinant human gamma interferon at concentrations of 8 to 16 U/ml. The interferon was titrated by observing a total inhibition of parasite plaque formation 7 days after infection. Inhibition of the growth of T. gondii in the early days after infection was measured by marked reductions in the incorporation of radioactive uracil, a precursor that can only be used by the parasites. This assay showed that when cells were pretreated with gamma interferon for 1 day and then infected, inhibition of T. gondii growth could be readily detected …

Vital Signs, Spring 1984, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Intracranial Tumour In An Infant Presenting As Iron Deficiency Anaemia, Rashid Jooma, D N. Grant

Section of Neurosurgery

No abstract provided.

Screening Of Patients At High Risk For Cancer, Robert M. O'Bryan

Henry Ford Hospital Medical Journal

A cancer other than non-melanoma skin cancer will occur in one of every seven persons. Individuals with higher risks for cancer are those with increasing age, hereditary disorders, and a family history of cancer. Lifestyle, especially the use of tobacco and alcohol, diet, and perhaps behavioral patterns influence the risk. Less well understood but clearly pertinent risk factors include environmental and occupational exposures. The risk factors specific for breast cancer include a positive family history of breast cancer, history of mastopathy, age at first pregnancy greater than 35 years, early menarche with late menopause, and history of carcinoma of the …

Brief Communication: Streptokinase For Deep Venous Thrombosis, Barry Lesser, Maria A. Sawdyk

Henry Ford Hospital Medical Journal

No abstract provided.

Pericardial Tamponade In Acute Myeloid Leukemia, R. P. Warrier, K. R. Kini, R. Singh, K. Maeda, I. Barr, F. M. Jara

Henry Ford Hospital Medical Journal

We are reporting a case of acute myeloid leukemia in a child with pericardial effusion and cardiac tamponade, with a review of the literature. Morphologic and cytochemical evidence was used to diagnose acute myeloid leukemia, and radiologic, electrocardiographic, echocardiographic, cytologic, and histologic evidence confirmed the diagnosis of tamponade and pericardial leukemic involvement. Pericardiotomy and pericardial window drainage successfully relieved the tamponade, and conventional chemotherapy was used to induce a remission.

Cushing's Disease Due To Pituitary Carcinoma, M. Saeed Zafar, R. C. Mellinger, J. L. Chason

Henry Ford Hospital Medical Journal

Criteria for the diagnosis of pituitary carcinoma are subject to controversy. Some authors do not accept the demonstration of cellular anaplasia alone as sufficient to establish the diagnosis but require evidence of metastatic disease in order to label a pituitary tumor as malignant. However, pituitary tumors can metastasize even in the absence of anaplasia. The present case of Cushing's disease and pituitary carcinoma had no clinical evidence of metastases when first reported. Partial surgical removal of the tumor followed by irradiation resulted in clinical remission of the Cushing's syndrome, but two years later progressive uncontrollable recurrence of the disease ended …