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Artificial Insemination Of Beef Heifers With Multi-Sire Semen, Dempster Christenson, Jordan M. Thomas, Daniel J. Kelly, Richard N. Funston Jan 2025

Artificial Insemination Of Beef Heifers With Multi-Sire Semen, Dempster Christenson, Jordan M. Thomas, Daniel J. Kelly, Richard N. Funston

Nebraska Beef Cattle Reports

This study compared pregnancy rates of beef heifers artificially inseminated with multi-sire semen to single-sire semen. It was hypothesized pregnancy rates resulting from multi-sire semen would be increased compared to single-sire semen. Heifers were artificially inseminated with semen from one of three single-sires or semen from a combination of the same three sires. Pregnancy rates did not significantly differ. Paternity testing suggests sire parentage can be unequal when semen is mixed from multiple sires. In summary, producers can expect similar pregnancy rates using single-sire and multi-sire semen, but progeny may have unequal sire representation.


Impact Of Overwinter Gain On Growth And Reproductive Performance In March-Born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. Mccarthy Jan 2025

Impact Of Overwinter Gain On Growth And Reproductive Performance In March-Born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. Mccarthy

Nebraska Beef Cattle Reports

Summary with Implications

Heifers developed to lower rates of overwinter gain may reduce development costs without growth and reproduction impacted. A 3-year study was conducted to evaluate different overwinter rates of gain on heifer growth rates, reproductive, and economic performance. Heifers were managed together and individually supplemented (January-May) with dried distillers grains to achieve either a low (0.75 lb/d) or high (1.50 lb/d) average daily gain. At breeding, high gain heifers were heavier than low gain heifers. Average daily gain and body condition score were similar between treatments. Overwinter treatment did not impact attainment of puberty, pregnancy rates, or the …


Impact Of Pre- And Post-Breeding Supplementation On Performance Of May-Born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. Mccarthy Jan 2025

Impact Of Pre- And Post-Breeding Supplementation On Performance Of May-Born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. Mccarthy

Nebraska Beef Cattle Reports

Summary with Implications This 3-year study compared growth, reproductive performance, and economics of May-born yearling heifers that either received 2.00 lb/ heifer/ per d of a dried distillers grain supplement from pre-breeding (July) through breeding (August) or no supplement. Supplementation was offered approximately 24 days before breeding, averaging 55 days total. Heifer body weight was unaffected by supplementation. Supplementation increased average daily gain until pregnancy diagnosis, but no differences were noted after pregnancy diagnosis. Providing dried distillers grain increased the percentage of heifers that were cycling before breeding; however, no differences in pregnancy rates, percent that gave birth in the …


Interaction Of Backgrounding System And Implant Use On Growing Calf Performance, Sydney T. Vanderhoff, Braden C. Troyer, Rebecca L. Mcdermott, Mitchell M. Norman, Brandon L. Nuttelman, Galen E. Erickson, Mary E. Drewnoski, James C. Macdonald Jan 2025

Interaction Of Backgrounding System And Implant Use On Growing Calf Performance, Sydney T. Vanderhoff, Braden C. Troyer, Rebecca L. Mcdermott, Mitchell M. Norman, Brandon L. Nuttelman, Galen E. Erickson, Mary E. Drewnoski, James C. Macdonald

Nebraska Beef Cattle Reports

Summary with Implications

A two-year study utilized 480 weaned steers each year targeted to gain either 1 or 2 lb/d during the winter followed by ad libitum forage intake during the summer to determine the effects of winter rate of gain and implant strategy during the winter backgrounding and summer phases on steer performance, forage intake, and compensatory gain. During the winter, steers received a Revalor-G or no implant. In the summer, steers either received a Revalor-IS or no implant. The use of Revalor-G and increased rate of gain during the winter backgrounding phase had additive effects to increase animal …


Quantifying Cereal Rye Pastures Biomass With Image Analysis, Pedro Henrique J. Fernandes, Shelby L. Davies-Jenkins, Biquan Zhao, Wei‑Zhen Liang, Mary E. Drewnoski, Yijie Xiong Jan 2025

Quantifying Cereal Rye Pastures Biomass With Image Analysis, Pedro Henrique J. Fernandes, Shelby L. Davies-Jenkins, Biquan Zhao, Wei‑Zhen Liang, Mary E. Drewnoski, Yijie Xiong

Nebraska Beef Cattle Reports

Summary with Implications

By accurately assessing the amount of forage available, producers can estimate the pasture carrying capacity to make informed decisions on management. To provide producers with a feasible and efficient approach to estimate forage mass, this project evaluated performance of two image analysis tools, Crop Canopy Image Analyzer (CCIA) and Canopeo, in estimating forage mass for cereal rye. Forage mass measured by clipping the forage (areas with 5.625 ft2) was correlated with plant cover analyzed by the two tools using photos of the forage taken 37 in above the ground. Results obtained have supported the feasibility …


Impact Of Constant Versus Variable Inclusions Of Modified Distillers Grains Plus Solubles On Feedlot Cattle Performance And Carcass Characteristics, Paige M. Madison, Rebecca L. Mcdermott, Isaque F. Vicci, Joshua R. Benton, James C. Macdonald, Galen E. Erickson Jan 2025

Impact Of Constant Versus Variable Inclusions Of Modified Distillers Grains Plus Solubles On Feedlot Cattle Performance And Carcass Characteristics, Paige M. Madison, Rebecca L. Mcdermott, Isaque F. Vicci, Joshua R. Benton, James C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

Summary with Implications

A finishing trial was conducted to evaluate the effects of varying dietary inclusion of modified distillers grains plus solubles compared to a constant inclusion throughout the entire feeding period on finishing cattle performance. Treatments were arranged as a 2 × 2 + 1 factorial with two inclusions of modified distillers grains plus solubles (10% and 25%) that were constant or varying in dietary inclusion, and a corn control (0% modified distillers grains plus solubles). Increasing the inclusion of distillers grains from 0 to 25% increased both DMI and ADG when fed at a constant inclusion of 10 …


Impact Of Full-Fat Wet Distillers Grains Inclusion In Steam-Flaked Corn Based Finishing Diets, Gatlin Hissong, Bill Dicke, Doug Smith, Andrea Watson, Galen E. Erickson Jan 2025

Impact Of Full-Fat Wet Distillers Grains Inclusion In Steam-Flaked Corn Based Finishing Diets, Gatlin Hissong, Bill Dicke, Doug Smith, Andrea Watson, Galen E. Erickson

Nebraska Beef Cattle Reports

Summary with Implications

Steam-flaked corn and distillers grains are common feed ingredients in finishing rations, but the interaction between the two is not well understood. A finishing trial at a commercial feedlot using 700 calf-fed heifers was conducted to evaluate cattle performance when fed 18 or 30% (dry matter basis) full-fat wet distillers grains plus solubles in steam-flaked corn based diets with 8% roughage (hay + corn silage). No effects on cattle performance were observed due to distillers grains inclusion in the diet. Final body weight, dry matter intake, average daily gain, feed conversion, and hot carcass weight were not …


Effect Of Feeding Palm Oil On Finishing Cattle Performance, Carcass Characteristics, And Methane Production, Anna M. Kobza, Rebecca L. Mcdermott, Mitchell C. Norman, Joshua R. Benton, Long Zou, James C. Macdonald, Galen E. Erickson Jan 2025

Effect Of Feeding Palm Oil On Finishing Cattle Performance, Carcass Characteristics, And Methane Production, Anna M. Kobza, Rebecca L. Mcdermott, Mitchell C. Norman, Joshua R. Benton, Long Zou, James C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

Summary with Implications

Increased demand for biofuel production has increased demand and price of commonly fed supplemental fat sources in beef operations. This finishing study evaluated the effect of feeding palm oil products on performance, carcass characteristics and methane production of feedlot finishing steers. Dietary treatments were feeding no supplemental fat or feeding one of the following fat sources at 4% of diet dry matter: whole palm oil, palm stearin, palm olein, or corn oil. Feeding supplemental fat, regardless of source, increased final body weight, average daily gain, and hot carcass weight. Feeding supplemental fat had no effect on dry …


Effect Of Feeding Two Different Feed Additives (Optipartum C+ And Prime Force) On Finishing Cattle Performance And Carcass Characteristics, Sofia Suarez-Lorences, Rebecca L. Mcdermott, Joshua R. Benton, Robert Bondurant, Willard Lemaster, James C. Macdonald, Galen E. Erickson Jan 2025

Effect Of Feeding Two Different Feed Additives (Optipartum C+ And Prime Force) On Finishing Cattle Performance And Carcass Characteristics, Sofia Suarez-Lorences, Rebecca L. Mcdermott, Joshua R. Benton, Robert Bondurant, Willard Lemaster, James C. Macdonald, Galen E. Erickson

Nebraska Beef Cattle Reports

Summary with Implications

A feedlot study was conducted to evaluate the effects of adding two different natural feed additives, Prime Force and Optipartum C+, on finishing cattle performance and carcass characteristics. Treatments were applied as a 2×2 factorial that included a control diet with no additive; a diet containing Prime Force; a diet containing Optipartum C+; and a diet containing both Prime Force and Optipartum C+ combined. Treatment diets were fed the last 67 d prior to slaughter as designed. Cattle fed Prime Force had greater live final body weight, carcass weight, intake, and average daily gain compared to cattle …


Effects Of Replacing Wet Corn Distillers Grains With A Purefield Distillers Grains® At 15% And 30% (Dm Basis) In Feedlot Diets, Sofia A. Canafoglia, Pablo L. Loza Jan 2025

Effects Of Replacing Wet Corn Distillers Grains With A Purefield Distillers Grains® At 15% And 30% (Dm Basis) In Feedlot Diets, Sofia A. Canafoglia, Pablo L. Loza

Nebraska Beef Cattle Reports

Summary with Implications

A 2×2 +1 factorial experiment was performed to evaluate the effects of replacing wet corn distillers grain (WCDGS) with PureField distillers grains, a proprietary blend of wet distillers grains plus wheat middlings (Purefield LLC, Kansas, United States) at 15% or 30% of the diet (DM basis), on finishing performance and carcass characteristics. The inclusion of either byproduct resulted in improved steer performance, and carcass characteristics when compared to the treatment without the byproduct inclusion. No interactions between byproduct and inclusion level were observed for steer performance or carcass characteristics. A tendency for higher average daily gains was …


2025 Beef Cattle Report Jan 2025

2025 Beef Cattle Report

Nebraska Beef Cattle Reports

Cow-calf Nutrition, Reproduction, and Management

Artificial Insemination of Beef Heifers with Multi-sire Semen, Dempster M. Christenson, Jordan M. Thomas, Daniel J. Kelly, Rick N. Funston

Impact of Overwinter Gain on Growth and Reproductive Performance in March- born Heifers, Josie N. Crouch, J. Travis Mulliniks, Jacki A. Musgrave, Kacie L. McCarthy

Impact of Pre- and Post-breeding Supplementation on Performance of May-born Heifers, Josie N. Crouch, J. Travis. Mulliniks, Jacki A. Musgrave, Kacie L. McCarthy

Growing Calf and Yearling Management

Effects of Allocation Frequency on Cattle Performance and Forage Utilization when Swath Grazing a Sorghum-Sudangrass Hybrid in Eastern Nebraska, Thomas E. Aquino, …


Effect Of Using Whole Soybeans, Roasted Soybeans, Or Soybean Meal In Finishing Cattle Diets, Melissa K. Bausch, James C. Macdonald, Galen E. Erickson, Pablo L. Loza Jan 2025

Effect Of Using Whole Soybeans, Roasted Soybeans, Or Soybean Meal In Finishing Cattle Diets, Melissa K. Bausch, James C. Macdonald, Galen E. Erickson, Pablo L. Loza

Nebraska Beef Cattle Reports

Summary with Implications

A feedlot study compared the effect of using whole or roasted soybeans at two inclusion rates (12% and 16% of diet dry matter), soybean meal, distillers grains, or a dry-rolled corn with urea control in finishing cattle diets. Steers fed the diet with the 16% inclusion of roasted soybeans had better average daily gain, feed conversion, and hot carcass weight. All other diets resulted in similar performance to the dry-rolled corn and distillers grains treatments. Roasted soybeans fed at a 16% inclusion improved F:G over the 12% roasted soybeans as compared to the whole soybeans which were …


Size Of Age-0 Sander Vitreus Pre And Post Dreissena Polymorpha Infestation On Brainerd And Bemidji Area Lakes, Quady Bernu Jan 2025

Size Of Age-0 Sander Vitreus Pre And Post Dreissena Polymorpha Infestation On Brainerd And Bemidji Area Lakes, Quady Bernu

Journal of Earth and Life Science

Walleye Sander vitreus is the Minnesota state fish and a vital predator fish in lake ecology. Zebra mussels, Dreissena polymorpha were first found in Minnesota inland lakes in the 1980’s. These mussels have had huge impacts on water clarity as well as phytoplankton and zooplankton population levels which affect how age-0 fish feed, especially a low light feeding predator fish like walleye. A study took place on age-0 walleye size and it supported the conclusion that age-0 walleye were negatively impacted by zebra mussels in Minnesota’s large lakes. The goals of this study were to determine how the size of …


Microsatellites Reveal The Population Genetic Structure Of Yellow Perch In Minnesota, Megan Boche Jan 2025

Microsatellites Reveal The Population Genetic Structure Of Yellow Perch In Minnesota, Megan Boche

Journal of Earth and Life Science

When analyzing a population’s genetic makeup, looking at variation of individuals and populations is a crucial factor. The management of yellow perch will be aided by this information particularly in regard to stocking or relocation. Microsatellite loci were used to analyze the genetic population structure of yellow perch Perca flavescens within and among 29 sampling areas throughout Minnesota’s basins. Seven microsatellite DNA loci were evaluated, with heterozygosities ranging from 0.41 to 0.78. The Lower Mississippi basin samples showed higher numbers of alleles per locus and greater expected heterozygosities compared to other basins, with Lake Pepin (PEP) exhibiting the highest average …


Marine Heatwave Response Plan For Western Australia’S Wild Capture Fisheries And Aquaculture, Department Of Primary Industries And Regional Development, Western Australia Jan 2025

Marine Heatwave Response Plan For Western Australia’S Wild Capture Fisheries And Aquaculture, Department Of Primary Industries And Regional Development, Western Australia

Fisheries Management Papers

The purpose of the Western Australian wild capture fisheries and aquaculture marine heatwave response plan (the Plan) is to document the Department’s approach for identifying and responding to the hazard of a marine heatwave on wild catch fisheries (commercial, recreational, charter and customary) and aquaculture resources within the geographic boundaries of WA. It provides risk reduction strategies and establishes best-practice processes for each stage of the hazard management and response continuum, ensuring that DPIRD is able to adequately prepare for, respond to, and recover from marine heatwave events. This Plan operates in conjunction with WA’s existing aquatic resource management framework, …


Advancing Clinical Trial Readiness In White Matter Disease And Related Dementias: Key Steps For Future Research Progress, Pradoldej Sompol, Gregory A. Jicha, Jason D. Hinman, Adam M. Brickman, Steven M. Greenberg, Konstantinos Arfanakis, Marion S. Buckwalter, Irene Lorenzo Llorente, Jeff D. Williamson, Michael S. Wolf, Eric E. Smith, Aditi Gupta, Margaret E. Flanagan, Miguel A. Vazquez, Jeffrey M. Burns, S. Thomas Carmichael, Frank C. Barone Jan 2025

Advancing Clinical Trial Readiness In White Matter Disease And Related Dementias: Key Steps For Future Research Progress, Pradoldej Sompol, Gregory A. Jicha, Jason D. Hinman, Adam M. Brickman, Steven M. Greenberg, Konstantinos Arfanakis, Marion S. Buckwalter, Irene Lorenzo Llorente, Jeff D. Williamson, Michael S. Wolf, Eric E. Smith, Aditi Gupta, Margaret E. Flanagan, Miguel A. Vazquez, Jeffrey M. Burns, S. Thomas Carmichael, Frank C. Barone

Pharmacology and Nutritional Sciences Faculty Publications

White matter disease, a broad-spectrum term that covers various types of white matter lesions and degeneration, is strongly related to age-related neurodegenerative disorders including Alzheimer’s disease (AD), and vascular contributions to cognitive impairment and dementia (VCID) and Alzheimer’s related dementias (ADRD). There is no specific treatment for white matter disease. Therefore, basic research and clinical studies are essential for future outcomes. Since its formation in 2020, the Albert Research Institute for White Matter and Cognition (ARIWMC) mission has been to support white matter research by providing a forum for communication where basic and clinical scientists meet to discuss and debate …


Developmental Regulation Of Corazonin, Eclosion Hormone, And Bursicon Messages And Rnai Suppression Of Corazonin In Adult Female American Dog Ticks, Dermacentor Variabilis, Anirudh Dhammi, Brooke Bissinger, Loganathan Ponnusamy, Daniel E. Sonenshine, R. Michael Roe Jan 2025

Developmental Regulation Of Corazonin, Eclosion Hormone, And Bursicon Messages And Rnai Suppression Of Corazonin In Adult Female American Dog Ticks, Dermacentor Variabilis, Anirudh Dhammi, Brooke Bissinger, Loganathan Ponnusamy, Daniel E. Sonenshine, R. Michael Roe

Biological Sciences Faculty Publications

The insect molting process is critical to growth and development and is regulated in part by the neuropeptides corazonin, eclosion hormone, and α and β bursicon. We found messages in a synganglion transcriptome from adult, female American dog ticks, Dermacentor variabilis (that do not molt), with a high similarity to the larval insect neuropeptides that control molting. The phylogenetic analysis of the tick putative neuropeptides compared to other arthropods is discussed in detail. The relative gene expression of these peptides was determined by quantitative PCR during the following adult developmental stages: (i) virgin, unfed 0–24 h after entering the adult …


Living A Lie: The Truth Behind Isohydnocera Curtipennis (Newman) And Other Historically Confused Species Of Phyllobaenus Dejean, With The Description Of The New Genus Neohydnocera (Coleoptera: Cleridae: Clerinae: Hydnocerini: Hydnocerina), John M. Leavengood Jr. Jan 2025

Living A Lie: The Truth Behind Isohydnocera Curtipennis (Newman) And Other Historically Confused Species Of Phyllobaenus Dejean, With The Description Of The New Genus Neohydnocera (Coleoptera: Cleridae: Clerinae: Hydnocerini: Hydnocerina), John M. Leavengood Jr.

Insecta Mundi

Taxonomic changes in the New World Hydnocerina (Coleoptera: Cleridae: Clerinae: Hydnocer­ini) at the species and genus level are presented. Phyllobaenus suturalis (Klug, 1842) and Hydnocera limbata Spinola, 1844 are designated junior synonyms of P. pallipennis (Say, 1825), new synonymy. Phyllobaenus nigrescens (Schaeffer, 1909) is designated a junior synonym of P. verticalis (Say, 1835), new synonymy. Iso­hydnocera curtipennis (Newman, 1840), P. lineaticollis Spinola, 1844, and Clerus brachypterus Klug, 1842, are re-established as junior synonyms of P. verticalis (Say, 1835), status reinstated, and I. curtipennis is accordingly reassigned to Phyllobaenus Dejean as P. curtipennis …


Lack Of Consistent Diurnal Trends In Acoustic Metrics From Restored Coral Reefs, Jeremy Velázquez-Alvarado, Valentina Pérez-García, Javier S. Tellechea, Joni T. Backstrom, Alex Mercado-Molina Jan 2025

Lack Of Consistent Diurnal Trends In Acoustic Metrics From Restored Coral Reefs, Jeremy Velázquez-Alvarado, Valentina Pérez-García, Javier S. Tellechea, Joni T. Backstrom, Alex Mercado-Molina

Gulf and Caribbean Research

Once vibrant ecosystems, coral reefs are degrading at unprecedented rates due to natural and human—induced disturbances, necessitating immediate restoration and conservation efforts. Evaluating the success of these projects often involves assessing changes in reef biodiversity. Bioacoustics has emerged as a promising, non—invasive method for such evaluations, though its efficacy remains debated. This study aimed to determine whether the diurnal soundscapes of restored coral reefs are consistent across different time frames (months) and spatial scales (reefs), which is crucial for developing reliable monitoring tools for reef health. To achieve this, 2 commonly used acoustic indices, the Acoustic Complexity Index (ACI) and …


Elucidating The Genetic Regulation Of Zebrafish Type Ii Collagen Alpha 1 B, Angelina Renee Carcione Jan 2025

Elucidating The Genetic Regulation Of Zebrafish Type Ii Collagen Alpha 1 B, Angelina Renee Carcione

Dissertations

Type II collagens (Col2) are essential proteins providing flexibility and structure to vertebrate animals. During development type II collagens play a vital role in the formation of many structures, such as the cartilage of the skeleton, the notochord, the retina and many other tissues. Conserved throughout vertebrates, cartilage is composed of two main cell types: chondrocytes, which make up the bulk of the structure, and perichondral cells, which form the epithelial layer that surrounds chondrocytes and is essential for bone growth and joint protection. While much is known about the expression and regulation of type II collagens in chondrocytes, specifically …


Forage News [2025-07], University Of Kentucky Jan 2025

Forage News [2025-07], University Of Kentucky

Forage News

No abstract provided.


Body Size Distributions Of Riverine Freshwater Plankton Communities, Staci Ann Reynolds Jan 2025

Body Size Distributions Of Riverine Freshwater Plankton Communities, Staci Ann Reynolds

Dissertations and Theses

The individual size distribution (ISD) is an individual based model that estimates the relative abundance of individual body sizes in a community. ISD’s slope or lambda (λ) gives insight into the communities’ food web and energy transfer. Climate change is expected to shift mean body sizes and λ as it increases individuals’ energy demands. Alterations in food webs and spatial distribution throughout the middle Missouri River basin may also have an impact on these communities λ. In a mesocosm experiment and field study, planktonic communities were sampled and had body sizes measured. Generalized linear mixed models were fit to calculate …


Snake Venoms As Models For Understanding The Origins And Evolution Of Gene Regulatory Networks, Siddharth S. Gopalan Jan 2025

Snake Venoms As Models For Understanding The Origins And Evolution Of Gene Regulatory Networks, Siddharth S. Gopalan

Biology Dissertations - Archive

Understanding the relationship between genotype and phenotype is a fundamental goal of biology. However, the vastly complex nature of eukaryotic gene regulation can make deriving precise relationships between genotype and phenotype challenging. The gene regulatory architecture of snake venom systems provide an opportunity to study this problem in a phenotypic system with immense variation in phenotypes and the underlying genetics. Using a set of integrated functional genomic approaches with snake venoms as a central model, in this dissertation, I provide several examples of the regulatory mechanisms by which diversity in phenotypes arises. Specifically, I identify how gene expression heterogeneity between …


Genetic Analysis Of Methionine Restriction-Associated Mitochondrial Unfolded Protein Response Signaling., Josh D. Dodge Jan 2025

Genetic Analysis Of Methionine Restriction-Associated Mitochondrial Unfolded Protein Response Signaling., Josh D. Dodge

Biology Dissertations - Archive

The lifespan of an organism is dictated by various genetic and environmental factors. One such determinant is the health of mitochondria which are organelles that mediate various critical cell functions including a significant role in generating the vast supply of cellular energy. Indeed, the gradual decline of mitochondrial function is believed to be a hallmark and possible cause of aging. Paradoxically, mild mitochondrial dysfunction early in life extends lifespan in various model organisms. Cells use diverse approaches to promote mitochondrial homeostasis, including the transcriptional reprogramming of cells by mitochondrial unfolded protein response (UPRmt) to mitigate mitochondrial stress. Consistently, UPRmt activation …


The Effects Of Speed, Grade And Footwear On Knee Adduction Moment And Tibial Shock, Alexis C. Gant Jan 2025

The Effects Of Speed, Grade And Footwear On Knee Adduction Moment And Tibial Shock, Alexis C. Gant

Kinesiology Dissertations - Archive

Knee osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage deterioration, chronic pain, and reduced mobility. Alterations in gait mechanics, particularly increased knee adduction moment (KAM) and tibial shock, are strongly associated with OA onset and progression. These biomechanical markers reflect abnormal joint loading and provide valuable insights for developing non-invasive interventions. This dissertation investigates how modifiable external factors, specifically walking slope, footwear type, and walking speed, influence knee joint loading patterns. The goal is to inform rehabilitation strategies that can decrease joint stress, alleviate symptoms, and slow disease progression.

Study 1 examines the effects of walking slope …


The Role Of Sodium Butyrate As An Inflammatory Regulator And Its Effect On Long Noncoding Rnas In Neuroinflammation, Angel Covarrubias Jan 2025

The Role Of Sodium Butyrate As An Inflammatory Regulator And Its Effect On Long Noncoding Rnas In Neuroinflammation, Angel Covarrubias

Chemistry & Biochemistry Theses - Archive

Inflammation is a crucial homeostatic process that contributes to both the elimination of foreign invaders and tissue repair. Inflammation at sites of tissue injury or infection is initiated by the detection of a harmful stimulus, triggering vital inflammatory immune signaling pathways and a cascade of cytokines and inflammatory mediators. The dysregulation of this process, however, can result in inappropriate inflammatory responses manifesting in tissue damage and compromised cell function. Dysregulation of the inflammatory response is seen frequently in many human diseases such as Diabetes, Cancer, cardiovascular disease, and neurodegenerative diseases.

In the context of the Central Nervous system, inflammation is …


The Evolution Of The Stress Response In The Trinidadian Killifish: Ecological Drivers And Maternal Mediation, Mikaela E. Feder Jan 2025

The Evolution Of The Stress Response In The Trinidadian Killifish: Ecological Drivers And Maternal Mediation, Mikaela E. Feder

Biology Dissertations - Archive

Ecological variables can induce the stress response in organisms. Yet, few studies have tested for evolutionary shifts in stress responses across ecological gradients. In these studies, we used Trinidadian killifish found in sites with predators (high predation, HP) and sites where they are the only fish present (killifish only, KO). HP and KO populations differ in a suite of behavioral and life-history traits, making the Trinidadian killifish an excellent model to examine evolutionary physiology. My dissertation addresses the knowledge gap by examining: (1) how baseline cortisol differs in wild-caught Trinidadian killifish found in HP and KO sites, (2) the influence …


Atorvastatin Alters Neuronal Morphology Data Set, Carolyn L. Pytte Jan 2025

Atorvastatin Alters Neuronal Morphology Data Set, Carolyn L. Pytte

Publications and Research

Statins are highly effective and widely prescribed cholesterol lowering drugs. However, statins cross the blood-brain barrier and decrease neural cholesterol in animal models, raising concern that long-term statin use may impact cholesterol-dependent structures and functions in the brain. Cholesterol is a fundamental component of cell membranes and experimentally decreasing membrane cholesterol has been shown to alter cell morphology in vitro. In addition, brain regions that undergo adult neurogenesis rely on local brain cholesterol for the manufacture of new neuronal membranes. Thus neurogenesis may be particularly vulnerable to long-term statin use. Here we asked whether oral statin treatment impacts neurogenesis …


Examining Purkinje Cell Modulation Of The Vor: An Optogenetic Study, Ben Davis, D Garcia, B Haack, J Lewis, J Jackson, C Worthington, Trace Stay Jan 2025

Examining Purkinje Cell Modulation Of The Vor: An Optogenetic Study, Ben Davis, D Garcia, B Haack, J Lewis, J Jackson, C Worthington, Trace Stay

Library/Life Sciences Undergraduate Poster Competition 2025

The vestibulo-ocular reflex (VOR) is coordinated eye movement to maintain a stable gaze during head rotation. This reflex can be adapted in behavioral training by using repeated head movements and shifting visual stimuli.

Previous research (Kimpo et al., 2014) implicates cerebellar output as critical to VOR adaptation, but it is unclear whether Purkinje cell (PC) output paired with a vestibular or visual stimulus is sufficient for driving reflex adaptation.

We hypothesize that PC output is sufficient for driving gain up behavioral VOR adaptation when paired with peak ipsiversive head movement in mice. Stimuli include a rotating vestibular environment or visual …


Population Monitoring Of Packera Castoreus, Autumn Gudmundsen, Madison Huie, Steve Flinders, Loreen Allphin Jan 2025

Population Monitoring Of Packera Castoreus, Autumn Gudmundsen, Madison Huie, Steve Flinders, Loreen Allphin

Library/Life Sciences Undergraduate Poster Competition 2025

Packera castoreus is a rare flowering plant, endemic to high elevations in the Belknap volcanic substrates of the Tushar Mountains of Utah (fig.1 & 2).

  • The species has been classified as high priority for monitoring and conservation by the Utah Native Plant Society.1

There have been conservation concerns for rare alpine species recently due to increased threats, primarily:

  • Grazing from large ungulates (mountain goats, deer, & elk)2
  • Human impacts (especially hiking)1
  • Climate change1

To better understand the impacts of these various threats on P. castoreus, we monitored populations from 2018-2022 and assessed plant morphology, community composition, and population …