Digital Commons Network^™

Speed Of Intravenous Fluid On Glycocalyx Integrity And Central Blood Volume In A Porcine Septic Shock Model, Yosef Levenbrown, Md Jobayer Hossain, Paul T. Fawcett, Marjorie Postell, Anne M. Hesek, Lynell S. Jones, James P. Keith, Thomas H. Shaffer

Department of Pediatrics Faculty Papers

BACKGROUND: It is unclear whether the rate of intravenous fluid (IVF) administration in sepsis influences glycocalyx breakdown. This study aimed to measure the effect of rapid versus slow fluid bolus in a septic pig model on the integrity of the glycocalyx by measuring the serum levels of heparan sulfate and syndecan-1, breakdown products of the glycocalyx. Because endothelial glycocalyx is composed of apical cell membrane-bound proteoglycans such as syndecan-1, covalently bound with long linear glycosaminoglycans such as heparan sulfate, shedding of these different glycocalyx components is closely related. Additionally, we measured central blood volume (blood volume in the heart and …

Navigating Study Abroad: Improving Western Michigan University Students' Understanding Of University-Approved Provider Programs Through A Website Redesign, Gillian Gold

Honors Theses

Study abroad is a valuable opportunity for students' personal and professional development and is offered in various study abroad models and frameworks, including university-run or externally-run. Western Michigan University offers various options, including Faculty-Led Programs, WMU Exchange Programs, Partner Study Abroad Programs, University-Approved Provider Programs, International Internships, and Independent Study Abroad Opportunities. The University-Approved Provider Programs option at WMU allows students to study abroad through a provider that could more directly meet their interests and goals due to the personalized options available. Despite the benefits of the University-Approved Provider Programs, participation in these programs is low. The information about this …

Development Of Purposeful Movement Breaks And Sensory Pathways To Enhance Student Engagement And Participation, Ashlyn Houck

Capstone Projects

Children in school settings frequently spend extended periods seated in classrooms, which can make it difficult to meet their sensory and movement needs throughout the school day. When these needs are unmet, students may demonstrate behaviors that disrupt learning and limit participation in classroom activities. This capstone project addressed the need for sensory and movement opportunities within the school environment. Objectives included establishing a baseline of teacher knowledge related to the sensory systems, implementing movement breaks within daily classroom routines, and introducing sensory opportunities in hallways to support smoother transitions. The project was implemented with second- and third-grade classrooms. Outcomes …

Practical Exploration Of The Role Of Occupational Therapy In A Nature-Based School Setting, Emma Campbell

Capstone Projects

School-based occupational therapy (OT) plays a critical role in supporting children’s participation, development, and engagement in educational environments. However, non-traditional school settings often lack therapeutic supports, such as OT services. The purpose of this doctoral capstone experience (DCE) is to explore and expand the role of occupational therapy within a non-traditional academic setting, specifically a nature-based preschool program. Sunflower Farm’s preschool program provides a unique learning environment that supports children’s development through farm-based learning. While this setting offers rich opportunities for exploration and growth, additional supports are needed to facilitate students’ sensory processing, self-regulation, and participation.

The objectives of this …

High Performance Ae-Cnn Model Enhanced Via Gaussian Augmentation For Rssi-Dependent Indoor Positioning In Wireless Sensor Networks, Kahlaa K. Al-Nassrawy, Ghaidaa A Al-Sultany

Karbala International Journal of Modern Science

Precise indoor positioning system remains a significant challenge within Wireless Sensor Networks (WSNs) due to the instability and noise sensitivity of Received Signal Strength Indicator (RSSI) data. This paper proposes an advanced hybrid deep learning framework designed for 2D indoor localization, utilizing RSSI measurements to predict human or object position. Furthermore, to enhance the robustness of the model against signal variance and promote its generalization capability under this uncertainty, a data augmentation strategy is applied using three methods: Gaussian Noise Injection (GNI), Gaussian Mixture Model (GMM), and Bayesian Gaussian Mixture Model (BGMM). The purpose of data augmentation is to simulate …

Danza Azteca As A Form Of Resistance To White Settler Colonialism, Miguel Martínez

International Journal of Human Rights Education

White settler colonialism is a systematic process by which Europeans and their descendants migrate to and settle in a new land with the explicit expectation of taking over the land, regardless of any Indigenous peoples that may live on the land (Speed, 2017; Wolfe, 2006). The Indigenous people who reside there can be exploited for labor, removed, exterminated or some combination of the three. In the process of settling the land, the settlers rename places, transform land use, create a new sense of cultural identity, and work to eliminate any remnants of what had existed prior to their arrival. Indigenous …

Mayan Language Pods: Language Preservation As A Human Right With Indigenous Latinx Mothers And Their Children, Johanna Estrella, Rosa M. Jiménez

International Journal of Human Rights Education

Public schools are facing a new diaspora of immigrant students entering their schools—Indigenous Latinx youth. There is considerable literature on immigrant communities and immigrant students, particularly the Latinx origin youth who are overwhelmingly classified as “English Learners.” Much less attention has been paid to Indigenous immigrant youths’ educational and lived experiences. In response, indigenous families are seeking alternative ways to preserve their language and culture. This qualitative study documents a planned non-formal language preservation project with Mam Indigenous mothers and their children. Using Human Rights in Education (HRE) and Linguistic Rights frameworks, we analyze the Mam Language project as a …

Making Fun Of The Leader Of The Free World: South Park And Its Critique Of Donald Trump, Kenneth H. Mcmillen

Linfield University Student Symposium: A Celebration of Scholarship and Creative Achievement

South Park is one of the cornerstones of American television. It also is a show that doesn’t shy away from controversy or social commentary. In its runtime it has taken aim at celebrities, world leaders, movements, and entire groups of people. The latest of its targets is President Donald Trump, who has been one of the central subjects of the shows two 2025 seasons. To examine how these episodes manage to critique trump so thoroughly without alienating his supporters, I ask the following research question: How does South Park use parody to make critiques about Donald Trump’s ego?  I …

Steven Universe & The Phenomenon Of Family, Jabari J. Whipple

GS4 Student Scholars Symposium

This research analyzes Steven Universe, a modern animated television series created by Rebecca Sugar, through a sociological lens to explore how contemporary media redefines the concept of family. The study examines how nontraditional caregiving structures and emotionally based kinship challenge the boundaries of the nuclear family model. Using the theoretical frameworks of symbolic interactionism and feminist theory, this paper interprets family as a social construction formed through love, care, and shared experience rather than biology alone. A purposive sample of fifteen episodes across seasons one, three, and five was analyzed for depictions of caregiving, gender roles, and emotional labor. Findings …

Assessing Decision Making Under Risk And Dynamic Task Environments In Humans, Dylan J. Cato

GS4 Student Scholars Symposium

This research evaluates the theoretical foundations of recent embodied and enacted decision- making models(Baker., et al  2022) , specifically investigating whether "urgency" serves as a domain-general mechanism for reward-rate maximization. Across three experiments using a reward-performance contingency, we compare traditional decision-making frameworks with urgency-based theories to determine how participants navigate task demands and whether optimality assumptions hold (Reynaud, et al 2020). A primary focus involves testing whether motor excitability increases directly with evidence, or if "higher-level" deliberation occurs in parallel with se Using the Generalized Drift-Diffusion Model (GDDM) framework via PyDDM  (Shinn, et al 2020), we will …

Assessment Of Airborne Cultural Fungi Indoors And Outdoors In A Rural Veterinary Clinic, Elena Ortez, Oluwatosin Jegede, Dorothy Seybold, Daeshjea Mcgee, Atin Adhikari, Ally Holmes

GS4 Student Scholars Symposium

Background and Objectives: Veterinary clinics can inadvertently release and propagate bacteria through several mechanisms, primarily due to contaminated surfaces, insufficient cleaning protocols, and, in some instances, direct transmission from infected animals or staff. Given that these clinics are high-traffic environments, they can serve as hotspots for clinic-acquired infections if rigorous hygiene practices are not upheld. This study evaluated airborne bacterial concentrations in different areas of a veterinary clinic compared to outdoor ambient air by calculating the indoor-to-outdoor ratios.

Methods: Airborne culturable bacterial samples were collected using a Biostage Impactor across eight internal zones including waiting areas, treatment rooms, and wards …

Let's Talk About Age, Baby!, Kathryn Ravasio, Hector Mendoza

Undergraduate Research and Engagement Symposium

The Longevity Gap refers to the intriguing difference in life expectancy between males and females. In C. elegans, XX chromosome animals live longer than those with XO chromosomes. This study examines if XOL-1, the protein that acts as the master regulator of sex determination, is involved in this difference in aging.

Morphological Identification Of Echinostomas Found Within Dabbler And Diving Ducks, Sammy Schneider, Emma Harms, Miana Risser, Madison Becker

Research & Creative Achievement Day

Most ducks can be separated into two categories, dabblers or divers, depending on their feeding guild. Dabbler ducks are surface feeders and consume vegetation while diver ducks feed below the surface and consume aquatic animals. The Echinostoma species present in ducks may vary depending on their feeding guild. Three species of ducks from various regions of Wisconsin were donated by hunters for examination of endoparasites, particularly those from the genus Echinostoma. The sites of collection included Trempealeau, Marionette, and Onalaska. One species of dabbler duck, Gadwall (Mareca strepera), and two species of diver ducks, Lesser Scaup (Aythya affinis) and Canvasback …

The Evolution Of Accounting: Historical Bookkeeping And Double Entry, Linda N. Moua

Research & Creative Achievement Day

In present-day accounting, technology  has transformed the efficiency and effectiveness of transaction recording.  Microsoft Excel has become a standard tool since its launch in the 1980s and has  quickly replaced handwritten work. This research aims to analyze the origins  of accounting, specifically in bookkeeping and double-entry, and how it has  proven to be the language of business from the beginning. This research will  initially look at stone tablets from the Mesopotamian Era and into the  development of double entry, with how its evolved origins are still similar  and different today. Other than the history of bookkeeping and double entry,  there …

Comparing Dissection Vs Literature Data Of Cestodes In Ducks, Sophia B. Cross

Research & Creative Achievement Day

Cestodes are a class of parasites that are often found in vertebrate animals, specifically ducks. Research conducted by Winona State University students showed that cestodes were the most prevalent type of parasites found within ducks. However, outside research provides controversy as to whether this is actually true. Ducks were dissected by Winona State students over the past seven years, and their internal organs were carefully inspected under a light microscope. Ducks were donated by hunters, mostly harvested along the Mississippi River, from Buffalo City, WI to Winona, MN. Parasites were obtained, stored, and labelled from each duck. A dichotomous key …

Reframing Alpha-Gal Syndrome As A One Health Oral Health Risk: A Theoretical Model For Dental Safety And Policy Reform, Oyebolu Aderinola Akinkugbe, Akuchinyere Titus-Okpanachi, Oluwatosin Marylyn Oduneye

Liberty University Research Week

No abstract provided.

Manual Tissue Slicer Designed For Ovarian Tissue Cryopreservation, Levon Shukrian, Caleb Anene, Daniel Archer, Derek Works, Jack Durham, Joby Anthony, Jumana Rizk, Maria Mendoza Lopez, Shanice Rerrie

Liberty University Research Week

Fertility preservation techniques such as ovarian tissue cryopreservation and autotransplantation provide important options for patients at risk of primary ovarian insufficiency due to medical treatments or disease. A critical step in this process is the preparation of uniform ovarian cortical slices (0.5–1.5 mm thick) that preserve follicular architecture prior to cryopreservation. However, the discontinuation of the Stadie-Riggs tissue slicer, previously used for fresh tissue slicing, has created a significant gap in both translational research and clinical practice. To address this need, a compact manual ovarian tissue slicer was designed and constructed using biocompatible 316L stainless steel and borosilicate glass. The …

Artificial Meaning?, Thomas R. Lee, Jesse Egbert

Florida Law Review

The textualist turn is increasingly an empirical one—an inquiry into ordinary meaning in the sense of what is commonly or typically ascribed to a given word or phrase. Such an inquiry is inherently empirical. And empirical questions call for replicable evidence produced by transparent methods—not bare human intuition or an arbitrary preference for one dictionary definition over another. Both scholars and judges have begun to make this turn. They have started to adopt the tools used in the field of corpus linguistics—a field that studies language usage by examining large databases (corpora) of naturally occurring language.

This turn is now …

Identification Of An Unknown Bacterial Species From A Sink Handle, Angelo Ricarte, Ahman Dye

Undergraduate Research and Engagement Symposium

This project aims to identify an unknown bacterial species isolated from a sink handle. Using a series of tests, the bacterium’s physical appearance, growth conditions, and metabolic characteristics will be examined. Its shape, colony appearance, and responses to different biochemical tests will help narrow down its identity. By comparing these results with the profiles of known bacteria, this project aims to determine which species is present and better understand the types of microbes commonly found on everyday objects.

Non-Alcoholic Fatty Liver Disease, Diet And Contributing Factors: A Narrative Literature Review, Rachel Joseph, Ashley Tharpe, Sherri Ann Walker

Wisdom & Compassion: The LUSON Journal

Objectives: The purpose of this narrative literature review is to explore the relationship between Non-alcoholic fatty liver disease (NAFLD) and dietary habits, and identify factors that contribute to the development, progression, and potential management of NAFLD.

Methods: Search terms such as non-alcoholic fatty liver disease (NAFLD), diet, and nutrition, including plant-based and vegetarian diets, were used to identify 45 peer-reviewed publications published within the last five years.

Results: Dietary factors, biological, environmental, obesity, mental health, and genetic factors can contribute to the development of NAFLD. This multisystem problem can have economic, social, and psychological consequences that affect a person’s quality …

Multi-Omics Systems-Guided Insights Of Withanolide And Other Bioactives Contributions To Anti-Stress And Endurance Outcomes In Withania Somnifera, Deepak Mundkinajeddu

Oxford ICSB

Conventional Ashwagandha standardization is largely focused on total withanolide quantification, without insights on the functional contribution of other phytochemical fractions. In this discovery-driven development program, orthogonal array–based model combined with predictive transcriptomics was used to delineate the relative biological roles of withanolide and other bioactive components within Withania somnifera extracts. Validated animal models showed that withanolide-enriched fractions significantly reduced serum cortisol (p< 0.05), while other bioactive-enriched fractions significantly increased run-time to exhaustion (p< 0.05), confirming anti-stress and endurance mechanisms. By linking the phytochemical profile with predicted biological pathway activity, the composition of the extract is rationally optimized for the development of a standardized extract (Ashwa.30), designed to deliver both anti-stress and endurance benefits at a dose of 30 mg. Clinical evaluation of the Ashwagandha extract demonstrated significant reductions in perceived stress scores and circulating cortisol levels, alongside measurable improvements in endurance parameters compared to placebo (p< 0.05), confirming translational alignment from preclinical discovery to human outcomes. Untargeted metabolomic profiling revealed enrichment of glycine and serine metabolism, methionine metabolism, phenylalanine and tyrosine metabolism, and homocysteine degradation pathways. These integrated metabolic changes worked together to improve energy production, support mitochondrial repair, maintain antioxidant balance, and help reset the body’s stress response system. This work presents a systems-biology–based approach to holistic Ashwagandha standardization, integrating withanolides and complementary bioactivities. It establishes a precision-driven framework for clinically validated adaptogenic efficacy.

Temporal Variation In Dna Methylation Over 115 Years Post Introduction Facilitate Success Of House Sparrows, M. Ellesse Lauer, J. Dylan Maddox, Kevin D. Kohl, Mark Ravinet, Lynn B. Martin, Aaron W. Schrey

GS4 Student Scholars Symposium

House sparrows (Passer domesticus) have colonized most continents within the last 200 years. As such, they represent a unique study system for understanding the role that epigenetic mechanisms play in an individual’s responses to rapid environmental changes. DNA methylation facilitates the introduction success of non-native sparrows by compensating for reduced genetic diversity and supporting changes to phenotypes. In non-native populations of house sparrows, more recently introduced populations have higher variance in DNA methylation and respond to simulated infections with a greater magnitude of change in DNA methylation. To determine how DNA methylation changes temporally across 115 years post …

Briefly Noted: Raven And Crow: The Mythology, Art And Science Of Our Favorite Black Birds By Ellen W. Williams By Ellen W. Williams, Janet Croft

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

Review of Raven and Crow: The Mythology, Art and Science of Our Favorite Black Birds by Ellen W. Williams, McFarland, 2025.

Russell Hoban: Faithful To The Strange By Graeme Wend-Walker, Nicholas Birns

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

This is a review of David Wend-Walker's critical book on the fiction of Russell Hoban.

From Viðkenning To Valarindi: The Enigma Of Goldberry And The River-Woman, Derek Simon

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

THIS IS A TWO-PART ARTICLE. IN ORDER TO READ OR DOWNLOAD THE OTHER PART, FOLLOW THE LINK AT THE END OF THIS ABSTRACT.

Building upon the previous examination of the eddic and skaldic contours of Goldberry’s River kenning names, this reading of Goldberry’s enigma focuses on the mythological referents of her kinship relations and their narrative consistency in the legendarium.  Tending to the intrinsic connection between “[t]he incarnate mind, the tongue, and the tale” (Tolkien, On Fairy Stories, 41), I contend that the poetics of kenning diction sustain if not demand a reading of the River-woman references mythologically through …

What Are C.S. Lewis's Eldila And Why Do They Matter?, Joseph Weigel

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

This article explores the eldila from C.S. Lewis’s Ransom Trilogy. Many of the eldila in the trilogy are angelic beings. However, Lewis uses the nine orders of angels in the trilogy and different eldils correspond to different types of angels within the hierarchy. Additionally, eldila, on occasion, can refer to the entirety of the supernatural realm, including the mysterious longaevi. Through the trilogy, Lewis is portraying the rich supernatural worldview presented in the Scriptures that is so often ignored, even by Christians. For Lewis, angels, devils, and the whole realm of spirits, was a reality of the cosmos, …

Pier’S Barn And Aslan’S Stable: Satire And Sublimity In Langland’S Piers Plowman And Lewis’S The Last Battle, Tiffany E. Schubert

Mythlore: A Journal of J.R.R. Tolkien, C.S. Lewis, Charles Williams, and Mythopoeic Literature

The stable in The Last Battle is rather mysterious. It seems a random bit of architecture plopped in Narnia, whose primary structures are cozy caves or castles by the sea. Of course, the stable is an important Christian symbol, the humble birthplace of Christ himself. Nevertheless, Lewis’s stable does not function in any straightforward way as the Narnian version of “Away in a Manger.” Rather, it is a place of deception and violence, housing the false Aslan and serving as the focal point of an apocalyptic battle that ends with the destruction of all Narnia. There is medieval precedent for …

Unmasking Ashwagandha Controversy: Safety, Toxicity, And Adulteration, Tahir Maqbool Mir

Oxford ICSB

Ashwagandha (Withania somnifera) is an adaptogenic shrub valued for its roots, which support systemic health. Increasing use has raised safety concerns about adulteration and hepatotoxicity. The roots of ashwagandha are primarily preferred for systemic health, while the leaves were traditionally reserved for topical applications to treat joint inflammation and promote wound healing.  Although generally considered safe, ashwagandha supplements have been linked to drug-induced liver injury, including cholestasis, jaundice, and pruritus. Reports from various organizations like LARB in the Netherlands indicate a rise in liver toxicity cases, possibly due to cytotoxic withafrin A and DNA-damaging withanone. A major concern is widespread …

Advancements In Botanical Toxicology, Characterization, And Regulatory Frameworks, Paula Brown

Oxford ICSB

No abstract provided.

Determinants Of Opioid-Relevant Exposure From 7-Hydroxymitragynine Products In The Evolving U.S. Marketplace, Igor Koturbash, Scott Alsbrook, George Pro

Oxford ICSB

Kratom’s U.S. market has rapidly evolved from largely botanical powders and capsules to products enriched in 7-hydroxymitragynine (7-OH), a potent mu-opioid receptor agonist that is typically present only at trace levels in leaf material. To quantify downstream behavioral health burden and contextualize it with real-world signals of product diffusion, we analyzed National Survey on Drug Use and Health (NSDUH) data (2021-2023) alongside public health alert trends and systematic online product surveillance. In NSDUH, 5.8% of adults met criteria for serious mental illness (SMI). SMI increased by 150% among adults with combined opioid use disorder (OUD) and kratom use between 2021 …