Digital Commons Network^™

Leveraging Neutrosophic Uncertainty Theory Toward Choosing Biodegradable Dynamic Plastic Product In Various Arenas, Mona Mohamed, Karam M. Sallam

Neutrosophic Systems with Applications

Numerous studies in recent years have documented the negative effects of plastic waste on the environment and human wellness. Due to their widespread usage in daily life, particularly in packaging, and their rising direct or indirect discharge into the environment, plastics are recognized as an emerging environmental hazard. Thus, this point is considered the first problem in this study. As a result, efforts to replace traditional plastics with bioplastics have intensified. However, studies regarding the effects of conventional and bioplastics (BioPs) are also important. Hence, biodegradable polymers for industrial and commercial usage are essential in the present day as an …

Modelling Filter Response Of Galactic Emission Line Spectra, Jessica Johnson, Christian Draper

Utah Space Grant Consortium

The overall goal of our research is to begin to make a map of the universe in order to find evidence for the cold dark matter theory. Dark matter, which is 85% of all matter, does not interact with light, making it invisible to telescopes. However, we know it exists due to its gravitational effects on visible matter, which can be hard to detect.

The Bio-Light; Increasing Auto-Bioluminescence, Paul Rodriguez, Lane Law

Utah Space Grant Consortium

Bioluminescence is a fascinating capability that has benefited society in a number of ways. One way bioluminescence has been used is in the medical field, where researchers use it to mark cancer cells in animal models. However, bioluminescence could be harnessed for another application. In this project, we will generate bioluminescent E.coli that can produce unnatural amounts of light. These auto-bioluminescent bacteria could rival NASA low activity lights on shuttles, that produce 20 to 300 lux of light. To achieve the minimum of 20 lux in a liquid culture of E.coli, we must first introduce a plasmid that contains the …

Hollow Hair And How Its Structure Helps Big Game Animals Thermoregulate, Taylor Millett, Wendy Schatzberg, Samuel Tobler

Utah Space Grant Consortium

The Pronghorn antelope is the animal known to have hollow hair strands among hunters and conservationists, yet no one seems to know what it actually looks like on the inside. In this study we examined what a hollow hair strand looks like under a microscope and how it helps with an animal’s thermoregulation. Thermoregulation is the ability to regulate body temperature within a livable range even when external temperatures fluctuate. We studied animals like Mule deer, Rocky Mountain elk, and Pronghorn antelope, as well as other big game animals, as they exhibit this trait in a unique manner. These animals …

Modeling The Effects Of Space Travel On The Cardiovascular System Using A Bio-Mimetic In Vitro Hagfish Protein Model Of The Myocardium, Emilee Rickabaugh, Elizabeth Vargis

Utah Space Grant Consortium

Long-term space travel is a harsh experience for the human body. Astronauts exposed to the effects of space travel often experience bone and muscle loss, as well as an increased risk of diseases, including heart disease[1]. While the human heart has shown an impressive ability to adapt to spaceflight, many of the long-term effects on cardiovascular health are unknown [2]. To plan for missions requiring longer flight durations, understanding these effects is neccessary to assess the risk to the astronauts undertaking these missions. However, evaluating these risks is difficult due to the lack of a sufficiently accurate model. While animal …

Using Landsat And Sentinel To Investigate Drivers Of Algal Growth In Utah Lake, Kaylee B. Tanner

Utah Space Grant Consortium

Earth observation satellites provide a valuable opportunity to study spatial and temporal water quality trends in ways that are not possible with research based on in-situ water sampling. We used data from Sentinel 2 and the Landsat missions to analyze algae blooms on Utah Lake, a large, shallow, freshwater lake in Utah that is experiencing water quality challenges. We found that algae blooms mainly occur in the shallow bays and along the eastern shoreline of the lake, and are correlated with water temperature and turbidity. Our results suggest a need for further research and use of remote sensing data to …

Multiple And Consecutive Genome Editing Using I-Gonad And Breeding Enrichment Facilitates The Production Of Genetically Modified Mice, Carolina R Melo-Silva, Cory J Knudson, Lingjuan Tang, Samita Kafle, Lauren E. Springer, Jihae Choi, Christopher M. Snyder, Yajing Wang, Sangwon V. Kim, Luis J. Sigal

Department of Microbiology and Immunology Faculty Papers

Genetically modified (GM) mice are essential tools in biomedical research. Traditional methods for generating GM mice are expensive and require specialized personnel and equipment. The use of clustered regularly interspaced short palindromic repeats (CRISPR) coupled with improved-Genome editing via Oviductal Nucleic Acids Delivery (i-GONAD) has highly increased the feasibility of producing GM mice in research laboratories. However, genetic modification in inbred mouse strains of interest such as C57BL/6 (B6) is still challenging because of their low fertility and embryo fragility. We have successfully generated multiple novel GM mouse strains in the B6 background while attempting to optimize i-GONAD. We found …

Do Plants Have The Cognitive Complexity For Sentience?, Ricard V. Solé

Animal Sentience

Are plants sentient? Like other aspects of the cognitive potential of plants, this is a controversial issue, often driven by analogies and seldom supported on solid theoretical grounds. Sentience is understood in cognitive sciences as the capacity to feel. I suggest that because of plants’ evolved adaptations to morphological plasticity, sessile nature and ecological constraints, they are unlikely to have the requisite cognitive complexity for sentience.

Advancing The Economic And Environmental Sustainability Of The Newgenerator Nonsewered Sanitation System, Shion Watabe, Hannah A. C. Lohman, Yalin Li, Victoria L. Morgan, Lewis Stetson Rowles, Tyler Stephen, Hsiang-Yang Shyu, Robert A. Bair, Cynthia J. Castro, Roland D. Cusick, Daniel H. Yeh, Jeremy S. Guest

Civil Engineering & Construction: Faculty Publications

Achieving safely managed sanitation and resource recovery in areas that are rural, geographically challenged, or experiencing rapidly increasing population density may not be feasible with centralized facilities due to space requirements, site-specific concerns, and high costs of sewer installation. Nonsewered sanitation (NSS) systems have the potential to provide safely managed sanitation and achieve strict wastewater treatment standards. One such NSS treatment technology is the NEWgenerator, which includes an anaerobic membrane bioreactor (AnMBR), nutrient recovery via ion exchange, and electrochlorination. The system has been shown to achieve robust treatment of real waste for over 100 users, but the technology’s relative life …

Downstream Hydrochemistry And Irrigation Water Quality Of The Syr Darya, Aral Sea Basin, South Kazakhstan, Bagdat Satybaldiyev, Baimurat Ismailov, Nurbek Nurpeisov, Kairat Kenges, Daniel D. Snow, Arindam Malakar, Omirzhan Taukebayev, Bolat Uralbekov

Daugherty Water for Food Global Institute: Faculty Publications

New hydrochemical measurements from the Syr Darya provide insights into factors affecting the composition and quality of a major freshwater source replenishing the Aral Sea. This river is heavily used for power and irrigation and crosses territories of four Central Asia republics. It is intensely managed, draining several major tributaries, many reservoirs, and numerous irrigation distribution systems and canals. Analysis of seasonal changes in dissolved ion concentrations using geochemical diagrams, elemental ratios, statistical correlation, and equilibrium modeling allowed the characterization of mineral formation processes that control the dissolved chemical composition. Measured water hydrochemistry and composition type differs substantially from previous …

An Incremental Based Approach For 3d Multi-Angle Point Cloud Stitching Using Icp And Knn, Pankti K. Patel

Theses and Dissertations

The basic principle of stitching is joining or merging any two materials or objects. 3D point cloud stitching is basically stitching two 3D point cloud together. 3D point cloud stitching is an emerging topic and there are multiple ways to achieve it. There are various methods for stitching which all have changes throughout the time. The existing methods do have shortcomings and have ignored the multiangle stitching of a same model or an object. This shortfall leads to many deficiencies in the ability of a stitching algorithm to maintain accuracy over the period. In this work I have introduced a …

Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Sydney Ruth Rester, Shelby Lynn Berry

Honors Theses

Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …

Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Shelby Lynn Berry, Sydney Ruth Rester

Honors Theses

Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …

A Study Of Biochar Production Via Continuous Vacuum-Assisted Pyrolysis, Max Wohlgenant

Graduate Theses & Non-Theses

The present study focuses upon the design, fabrication, and feasibility of the bulk production of scientific biochar for mobile delivery. In the 2022 annual report, the National Academies of Science, Engineering, and Medicine recommended the integration of mobile, decentralized reactors that employ flexible manufacturing and circular economic principles. Biochar production, involving the thermal degradation of biomass under an inert atmosphere to yield remediation media is an ideal material to satisfy this recommendation. Many potential application sites, such as abandoned mines, are remote and limit the construction of large infrastructure. The continuous vacuum-assisted pyrolysis (CVAP) reactor was designed to: increase biochar …

Dense & Attention Convolutional Neural Networks For Toe Walking Recognition, Junde Chen, Rahul Soangra, Marybeth Grant-Beuttler, Y. A. Nanehkaran, Yuxin Wen

Physical Therapy Faculty Articles and Research

Idiopathic toe walking (ITW) is a gait disorder where children’s initial contacts show limited or no heel touch during the gait cycle. Toe walking can lead to poor balance, increased risk of falling or tripping, leg pain, and stunted growth in children. Early detection and identification can facilitate targeted interventions for children diagnosed with ITW. This study proposes a new one-dimensional (1D) Dense & Attention convolutional network architecture, which is termed as the DANet, to detect idiopathic toe walking. The dense block is integrated into the network to maximize information transfer and avoid missed features. Further, the attention modules are …

Anticancer Activities Of Tetra-, Penta-, And Hexacyclic Phenothiazines Modified With Quinoline Moiety., Małgorzata Jel, Beata Morak-Młodawska, Rafał Korlacki

Department of Electrical and Computer Engineering: Faculty Publications

The quinoline molecule is a chemical motif showing a highly promising pharmacological potential. Its numerous derivatives introduced into medicine revolutionized in the treatment of many entities of disease. The presence of the quinoline system in the structure of phenothiazines made it possible to obtain new aza- and diazaphenothiazine derivatives that show promising anticancer potential. The aza-analogs of the phenothiazines are structurally modified phenothiazines by the substitution of one or both benzene rings in the phenothiazine ring system with various azine rings. This approach to the strategy of obtaining new substances with biological potential can be classified as molecular hybridization methods …

Understanding The Effect Of Nanointerfaces On Nanostructure And Mechanical Properties Of Semicrystalline Polymers Using Coarse-Grained Molecular Dynamic Simulations, Nayoung Kim

Honors College Theses

Polymer crystallization is a classical problem of polymer research. Many synthetic and natural polymers take the semi-crystalline form. Crystallization of polymers is a complex process associated with the partial alignment of their molecular chains. The final physical properties of semicrystalline polymers are determined by the degree of crystallinity and the size and orientation of the crystallites (nano- to micro-sized crystalline regions). Although it has been studied for many years, we still lack a fundamental understanding of the types of factors that influence the semicrystalline structure and how the structure affects the final properties. It is difficult because crystalline polymers are …

Implementation Of Methods For Cell Therapy Research And Assessment Of The Impact Of Cryopreservation, Samantha Lynes

Master's Theses

Cell therapy is the administration of living cells into a patient to prevent or treat a variety of diseases and illnesses. The cell therapy industry is rapidly expanding, and continued research is necessary for manufacturing safe and effective therapies. Although cell therapy manufacturing generally involves cryopreservation processes for storage, there are limited standards for cryopreservation processes and assays required to evaluate cell therapies post-thaw, and limited understanding exists about how a recovery period post-thaw could impact cell health. The overall goal of this thesis was to evaluate the effect of cryopreservation and potential subsequent recovery time on cell viability.

Because …

Detecting Pathobiomes Using Machine Learning, Valerie Jackson, Valerie Jackson

Industrial Engineering Undergraduate Honors Theses

Machine learning is a field with high growth potential due to the overall continuous progressions, developments, advancements, and improvements caused by the way it is used to help interpret and use large amounts of data [1]. One type of data that can be collected and analyzed by these machine learning models is data that is associated with DNA and information that the DNA gives. The research will be focusing specifically on using machine learning technology to detect pathobiomes indicative of salmonella pork. The pathobiome associated with salmonella is very similar to others, and this causes a problem for classification/detection with …

Development Of 3d Ovarian Cancer Spheroids In Vitro And Investigation Of Their Physiological Relevance As Models Of Inherent Chemoresistance, Amanda Murray

Honors College Theses

Ovarian cancer is the sixth leading cause of death among women worldwide, with an average 5-year survival rate of less than 48%. Current clinical treatment methods for this disease are often deemed ineffective because of the innate chemoresistance of tumors due to their microenvironment and architecture. Accurately mimicking chemoresistance with traditional 2D cultures is difficult; therefore, recent years have seen an increase in 3D culturing methods that create cellular spheroids. These spheroids can serve as models of in vivo tumor characteristics due to their hypoxic core, acidic microenvironment, and increased cell-to-cell interactions. This research aims to (1) refine a 3D …

Geophysical Assessment Of Internal Erosion Damage At The Crawford County Levee, Samuel Ross Hokett

Graduate Theses and Dissertations

Levee failures during flooding events can result in catastrophic loss of life and property. Soil erosion during high water events is a primary cause of levee failures. Accordingly, this research focuses on the geophysical assessment of internal erosion damage in levees. This thesis presents a case study utilizing Capacitively Coupled Resistivity (CCR), Direct Current Electrical Resistivity Tomography (DC ERT), and Multichannel Analysis of Surface Waves (MASW) to assess internal erosion damage at the Crawford County Levee System in Van Buren, AR, that occurred during the 2019 Arkansas River flood. Geophysical surveys acquired included longitudinal CCR, DC ERT, and MASW lines …

An In Vivo Biocompatibility Analysis Of A Novel Tissue Regeneration Matrix Using A Pig Model, Shamar Thomas

All Theses

The goal of this project is to develop an injectable bead scaffold to promote tissue regeneration in the void created by lumpectomy and to alleviate post lumpectomy problems by preventing local recurrence and minimizing surgical-related infections. Microbeads were synthesized from collagen type I and crosslinked with tannic acid to form the basis for this injectable therapeutic. Tannic acid acts as a therapeutic anticancer agent. The action mechanisms of tannins in breast cancer cells have been studied with studies showing tannins to be cytotoxic to cancer cells in a dose-dependent manner. Tannic acid induces apoptosis in breast cancer cells via caspase …

Guided Data Augmentation For Improved Semi-Supervised Image Classification In Low Data Regime., Fadoua Khmaissia

Electronic Theses and Dissertations

Deep learning models have achieved state of the art performances, especially for computer vision applications. Much of the recent successes can be attributed to the existence of large, high quality, labeled datasets. However, in many real-world applications, collecting similar datasets is often cumbersome and time consuming. For instance, developing robust automatic target recognition models from infrared images still faces major challenges. This is mainly due to the difficulty of acquiring high resolution inputs, sensitivity to the thermal sensors' calibration, meteorological conditions, targets' scale and viewpoint invariance. Ideally, a good training set should contain enough variations within each class for the …

Improving Inference Speed Of Perception Systems In Autonomous Unmanned Ground Vehicles, Bradley Selee

All Theses

Autonomous vehicle (AV) development has become one of the largest research challenges in businesses and research institutions. While much research has been done, autonomous driving still requires extensive amounts of research due to its immense, multi-factorial difficulty. Autonomous vehicles rely on many complex systems to function, make accurate decisions, and, above all, provide maximum safety. One of the most crucial components of autonomous driving is the perception system.

The perception system allows the vehicle to identify its surroundings and make accurate, but safe, decisions through the use of computer vision techniques like object detection, image segmentation, and path planning. Due …

Exploring The Effects Of Microarchitecture On Astrocyte Behavior And Vascular Remodeling In Spinal Cord Injury, Devin Gerber

Biomedical Engineering Undergraduate Honors Theses

Spinal cord injury (SCI) is a common condition and is characterized by traumatic and progressive damage that results in limited neuron regeneration and thus a restricted recovery. In SCI, the vasculature is also severely damaged, which exacerbates inflammation at the injury site. Specifically, insufficient angiogenesis occurs at the site of injury due to the fibrotic pathological microenvironment1 . SCI also leads to the formation of a fluid-filled cavity and thus gliosis and fibrosis, forming a dense glial and fibrotic scar around the cavity. The microenvironment at the injury site plays a significant role in astrocyte behavior, promoting the transformation of …

Analyzing The Influence Of Stale Data On Autonomous Intelligent Transportation Systems, August St. Louis

All Theses

Intelligent transportation has been at the forefront of recent technological advancement. Individuals have developed a number of algorithms intended to automate and improve essential intelligent transportation functions. New developments include the incorporation of vehicle platooning and path planning algorithms within a number of use cases. Data perturbation can affect both algorithms significantly. We define data perturbation as any natural or unnatural phenomenon that causes the data to be skewed in any way. Perturbations within either system can cause its respective algorithm to operate with stale or incorrect data. This can significantly affect performance. This paper conducts a fault injection campaign …

Effect Of Human Decellularized Skeletal Muscle On Recovery From Volumetric Muscle Loss Injury, Jacob Schluns

Graduate Theses and Dissertations

Volumetric muscle loss (VML) overwhelms muscle’s robust capacity for regeneration. A key event in the etiology of VML injury is the bulk loss of structural cues provided by the underlying extracellular matrix (ECM). While muscle is a highly structured tissue, with cell and ECM alignment in the direction of contractile force production, the impact of scaffold alignment on recovery remains unclear. Bulk human decellularized skeletal muscle (DSM) tissues were sectioned into 10 x 1-2 mm fibers. VML defects were repaired using multi-fiber implants consisting of approximately 8 fibers per defect arranged into two layers. Fibers were oriented 1) to the …

Mitral Valve Imaging And Biomechanics: A Workflow Towards Computational Modeling And Validation, Sam Stephens

Graduate Theses and Dissertations

The mitral valve serves a critical role in healthy cardiac function by ensuring the unidirectional flow of oxygenated blood from the left atrium into the left ventricle. It experiences the highest pressures found within the heart and its closure is the result of a complex interaction of several different structures that, furthermore, are unique to each individual. Despite the valve’s vital role however, the specific function of these constituent structures is not fully understood. This, confounded by its asymmetric, personalized nature, make surgical interventions for the mitral valve far less effective than for its neighboring aortic valve. Efforts to overcome …

Innovation For The Air: A Brief History Of Worldwide Aviation, Lauren Plumley

Honors Program: Senior Projects (Public)

The purpose of this report is to present a brief but comprehensive overview of the variety of innovations related to aviation, and to discuss their impact on scientific progress over the course of human history. Relevant discoveries from the fields of physics and aerodynamics, and the numerous technologies built based upon these discoveries, are discussed over a period ranging from ancient times to the twenty-first century. The scope of this report is an overview of the development of powered and unpowered aircraft, including lighter-than-air, heavier-than-air, and aerospace technologies. Aviation developments were generally not limited to one specific country or person, …

Closed-Loop, Recyclable Plastics From Ethyl Cyanoacrylate, Allison Joy Christy

Boise State University Theses and Dissertations

Ethyl cyanoacrylate, commonly known as super glue, has held a prominent role as an adhesive for decades due to its propensity to rapidly polymerize into poly(ethyl cyanoacrylate) (PECA) under ambient conditions. Ethyl cyanoacrylate monomers and their resulting PECA polymers are bio-friendly, which has allowed them to be used as medical adhesives and to be applied to drug delivery systems. However, PECA has not been used as a plastic material due to the perceived difficulty of handling the ethyl cyanoacrylate monomer. Here, we present a novel PECA plastic that displays thermal stability and tensile strength values that are comparable to atactic …